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Описание
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Таблетки Zoetis Апоквел, 16 мг, 16 мл, 20шт. в уп., 1уп.

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Артикул Маркета
103796608519
Тип препарата
Вид животного
Назначение средства
Форма выпуска
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После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью."},{"name":"Состав","value":"В 1 таблетке в качестве действующего вещества: оклацитиниба малеат (в пересчете на оклацитиниб) 16 мг, вспомогательные вещества: микрокристаллическую целлюлозу, лактозы моногидрат, карбоксиметил-крахмал натрия, магния стеарат, плёнкообразователь «Opadry II White» и воду очищенную."},{"name":"Показания к применению","value":"АПОКВЕЛ назначают собакам при дерматите, ассоциированном с аллергией (контактный, пищевой, паразитарный) в целях устранения зуда и уменьшения очаговых изменений кожи, а также для профилактики рецидивов атопического дерматита."},{"name":"Противопоказания","value":"Противопоказанием к применению АПОКВЕЛА является индивидуальная непереносимость животным его компонентов. Не допускается применение препарата собакам, с признаками иммуносупрессии, такими как гиперадренокортицизм, а также собакам, с прогрессирующими злокачественными новообразованиями. Не следует применять препарат кобелям в период вязки, собакам моложе 12-месячного возраста и/или массой менее 3 кг, а также щенным и кормящим сукам."},{"name":"Побочные действия","value":"Побочные явления и осложнения при кратковременном применении Апоквела могут проявляться угнетенным состоянием, расстройством функции желудочно-кишечного тракта, циститом; у животных, получающих Апоквел более 16 дней, приблизительно в 1% случаев может наблюдаться повышение аппетита и агрессия, кожные и подкожные новообразования, инфекции кожи, вызванные дрожжевыми грибками, увеличением лимфатических узлов, обострением демодекоза и онкологических заболеваний."},{"name":"Передозировка","value":"При передозировке лекарственного препарата у животного могут наблюдаться следующие симптомы: угнетенное состояние, рвота, диарея, локальные алопеции, утолщение кожной складки, образование струпьев и корочек, межпальцевые кисты, отек конечностей. Специфические антидоты отсутствуют, животному применяют симптоматическое лечение."},{"name":"Взаимодействие","value":"При совместном применении Апоквела с противомикробными, противовоспалительными и противопаразитарными препаратами фармакологического взаимодействия не выявлено. Не следует применять Апоквел совместно с иммунодепрессантами и противосудорожными препаратами."},{"name":"Особые указания","value":"Пустые флаконы из-под лекарственного препарата запрещается использовать для бытовых целей, они подлежат утилизации с бытовыми отходами. Особенности действия при первом применении препарата и при его отмене не выявлены. Следует избегать пропусков при введении очередной дозы препарата, так как это может привести к снижению эффективности. В случае пропуска очередной дозы, применение Апоквела возобновляют в соответствии с настоящей инструкцией. Апоквел не предназначен для применения продуктивным животным."},{"name":"Применение у беременных и кормящих животных","value":"не следует применять сукам в период беременности и лактации"},{"name":"Способ применения и дозы","value":"Апоквел применяют собакам перорально индивидуально с руки, или в смеси с кормом, или вводят принудительно в пасть в разовой дозе 0,4-0,6 мг оклацитиниба на 1 кг массы животного два раза в день, не более 14 суток; в качестве поддерживающей терапии при атопическом дерматите – один раз в сутки в той же дозе, но не более 14 недель. Схема и длительность курса применения препарата зависят от этиологии и патогенеза дерматита, клинического состояния животного и определяются лечащим ветеринарным врачом."},{"name":"Фармакокинетика","value":"после перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа"},{"name":"Условия отпуска","value":"без рецепта"},{"name":"Условия хранения","value":"Хранят препарат в закрытой упаковке производителя, в сухом, защищенном от света месте, отдельно от продуктов питания и кормов при температуре от 0 °С до 25 °С."},{"name":"Регистрационный номер","value":"840-3-20.20-4711№ПВИ-3-1.16/04707"},{"name":"Дата государственной регистрации","value":"20.02.2021"}]}},"fullSpecsGrouped":{"16464407836742971232":{"groups":[{"name":"Общие сведения","items":[{"value":"Zoetis","transition":{"params":{"glfilters":["7893318:13582700"]},"type":"catalog"},"name":"Бренд"},{"value":"лекарственный препарат","transition":{"params":{"glfilters":["34324371:35649313"]},"type":"catalog"},"name":"Тип препарата"},{"name":"Действующее вещество","value":"оклацитиниб"},{"name":"Форма выпуска","value":"таблетки для перорального применения"},{"value":"20 шт.","transition":{"params":{"glfilters":["14805583:20~20"]},"type":"catalog"},"name":"Количество в упаковке"},{"value":"16 мл","transition":{"params":{"glfilters":["24139073:16~16"]},"type":"catalog"},"name":"Объем"},{"name":"Упаковка","value":"банка"},{"value":"для кожи, при аллергии","transition":{"params":{"glfilters":["27143691:37167814,37167342"]},"type":"catalog"},"name":"Назначение средства"},{"value":"кошки, собаки","transition":{"params":{"glfilters":["43903290:44628264,44628228"]},"type":"catalog"},"name":"Вид животного"},{"value":"взрослые","transition":{"params":{"glfilters":["34074939:35635216"]},"type":"catalog"},"name":"Возраст животного"},{"name":"Минимальный возраст применения","value":"12 мес"},{"name":"Размер животного","value":"крупные породы"},{"name":"Минимальный вес животного","value":"13.5 кг"},{"name":"Максимальный вес животного","value":"80 кг"},{"name":"Страна производства","value":"Италия"}]},{"name":"Фармакологические свойства","items":[{"name":"Описание средства","value":"овальные таблетки белого или почти белого цвета, покрытые пленочной оболочкой, с разделительной бороздкой посередине и c надписью на обеих сторонах таблетки: L"},{"name":"Фармакологическая группа","value":"относится к лекарственным препаратам группы селективных ингибиторов янус-киназы (JAK)"},{"name":"Фармакологическое действие","value":"Апоквел относится к лекарственным препаратам группы селективных ингибиторов янус-киназы (JAK). Оклацитиниба малеат, входящий в состав препарата, в терапевтической дозе угнетает функции провоспалительных, проаллергических и пруритогенных (зудогенных) цитокинов, зависимых от ферментативной активности янус-киназы JAK1 или JAK3, целенаправленное воздействие на которые позволяет ингибировать ключевые механизмы возникновения зуда, ассоциированного с аллергией, и способствует устранению симптомов местного воспаления; на цитокины, участвующие в кроветворении и зависимые от JAK2, существенно не влияет. При длительном применении в более высоких дозах оклацитиниб может вызывать угнетение лимфоидной ткани, ингибировать активацию Т-клеток посредством подавления сигнала на уровне рецепторов интерлейкинов IL-2, что характеризует фармакологическое действие соединений данного класса. После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью."},{"name":"Состав","value":"В 1 таблетке в качестве действующего вещества: оклацитиниба малеат (в пересчете на оклацитиниб) 16 мг, вспомогательные вещества: микрокристаллическую целлюлозу, лактозы моногидрат, карбоксиметил-крахмал натрия, магния стеарат, плёнкообразователь «Opadry II White» и воду очищенную."}]},{"name":"Показания и противопоказания","items":[{"name":"Показания к применению","value":"АПОКВЕЛ назначают собакам при дерматите, ассоциированном с аллергией (контактный, пищевой, паразитарный) в целях устранения зуда и уменьшения очаговых изменений кожи, а также для профилактики рецидивов атопического дерматита."},{"name":"Противопоказания","value":"Противопоказанием к применению АПОКВЕЛА является индивидуальная непереносимость животным его компонентов. Не допускается применение препарата собакам, с признаками иммуносупрессии, такими как гиперадренокортицизм, а также собакам, с прогрессирующими злокачественными новообразованиями. Не следует применять препарат кобелям в период вязки, собакам моложе 12-месячного возраста и/или массой менее 3 кг, а также щенным и кормящим сукам."},{"name":"Побочные действия","value":"Побочные явления и осложнения при кратковременном применении Апоквела могут проявляться угнетенным состоянием, расстройством функции желудочно-кишечного тракта, циститом; у животных, получающих Апоквел более 16 дней, приблизительно в 1% случаев может наблюдаться повышение аппетита и агрессия, кожные и подкожные новообразования, инфекции кожи, вызванные дрожжевыми грибками, увеличением лимфатических узлов, обострением демодекоза и онкологических заболеваний."},{"name":"Передозировка","value":"При передозировке лекарственного препарата у животного могут наблюдаться следующие симптомы: угнетенное состояние, рвота, диарея, локальные алопеции, утолщение кожной складки, образование струпьев и корочек, межпальцевые кисты, отек конечностей. Специфические антидоты отсутствуют, животному применяют симптоматическое лечение."},{"name":"Взаимодействие","value":"При совместном применении Апоквела с противомикробными, противовоспалительными и противопаразитарными препаратами фармакологического взаимодействия не выявлено. Не следует применять Апоквел совместно с иммунодепрессантами и противосудорожными препаратами."},{"name":"Особые указания","value":"Пустые флаконы из-под лекарственного препарата запрещается использовать для бытовых целей, они подлежат утилизации с бытовыми отходами. Особенности действия при первом применении препарата и при его отмене не выявлены. Следует избегать пропусков при введении очередной дозы препарата, так как это может привести к снижению эффективности. В случае пропуска очередной дозы, применение Апоквела возобновляют в соответствии с настоящей инструкцией. 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Есть противопоказания, посоветуйтесь с врачом.
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
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Пэй
 
7 141 ₽
 
–1%
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Таблетки Zoetis Апоквел, 16 мг
Таблетки Zoetis Апоквел, 16 мг, 16 мл, 20шт. в уп., 1уп.
Задать вопрос
Цена с картой Яндекс Пэй:7 070 ₽
Скидка: 1%
–1 %
Вместо: 7 141 ₽
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Пушистая Аптека
Магазин•4.7 15 оценок
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Доставка Маркета
13 июн, по клику  0 ₽
Москва
13 июн, пункт выдачи  0 ₽
Москва
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  • Таблетки Zoetis Апоквел, 16 мг, 100 мл, 100 г, 100шт. в уп., 1уп., 16 мг
    19 %
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    Таблетки Zoetis Апоквел, 16 мг, 100 мл, 100 г, 100шт. в уп., 1уп., 16 мг
    Рейтинг товара: 4.6 из 5на основе 9 оценок
      , 
    Цена 39 501 ₽
    Пэй
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  • Таблетки Zoetis Апоквел, 3.6 мг, 25 г, 20шт. в уп., 1уп.
    1 %
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    Таблетки Zoetis Апоквел, 3.6 мг, 25 г, 20шт. в уп., 1уп.
    Рейтинг товара: 4.9 из 5на основе 124 оценки
      , 
    Цена 2 906 ₽
    Пэй
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  • Апоквел для собак таблетки (Zoetis) 16 мг. 20 шт. в уп.
    44 %
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    Апоквел для собак таблетки (Zoetis) 16 мг. 20 шт. в уп.
    Рейтинг товара: 4.8 из 5на основе 142 оценки
      , 
    Цена 9 026 ₽
    Пэй
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  • Таблетки Zoetis Апоквел, 5.4 мг, 26 г, 20шт. в уп., 1уп.
    31 %
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    Таблетки Zoetis Апоквел, 5.4 мг, 26 г, 20шт. в уп., 1уп.
    Рейтинг товара: 4.9 из 5на основе 40 оценок
      , 
    Цена 3 782 ₽
    Пэй
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  • Апоквел для собак таблетки (Zoetis) 16 мг. 20 шт. в уп.
    41 %
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    Апоквел для собак таблетки (Zoetis) 16 мг. 20 шт. в уп.
    Рейтинг товара: 4.7 из 5на основе 13 оценок
      , 
    Цена 7 088 ₽
    Пэй
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  • Таблетки Zoetis Апоквел, 5.4 мг, 20шт. в уп., 1уп.
    40 %
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    Таблетки Zoetis Апоквел, 5.4 мг, 20шт. в уп., 1уп.
    Рейтинг товара: 4.6 из 5на основе 104 оценки
      , 
    Цена 4 528 ₽
    Пэй
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  • Таблетки Ceva Экзекан 1 мг/10 мг/50 мг/300 мг, 149 г, 16шт. в уп., 1уп.
    1 %
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    Таблетки Ceva Экзекан 1 мг/10 мг/50 мг/300 мг, 149 г, 16шт. в уп., 1уп.
    Рейтинг товара: 4.8 из 5на основе 283 оценки
      , 
    Цена 1 486 ₽
    Пэй
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  • Таблетки Zoetis Римадил Р, 100 мг, 100 г, 20шт. в уп., 1уп., 100 мг
    2 %
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    Таблетки Zoetis Римадил Р, 100 мг, 100 г, 20шт. в уп., 1уп., 100 мг
    Рейтинг товара: 4.8 из 5на основе 21 оценка
      , 
    Цена 1 333 ₽
    Пэй
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  • Спрей Ветфарм Кортавет, 80 мл
    1 %
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    Спрей Ветфарм Кортавет, 80 мл
    Рейтинг товара: 4.6 из 5на основе 574 оценки
      , 
    Цена 2 079 ₽
    Пэй
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  • Таблетки Сева Экзекан, 140 г, 16шт. в уп., 1уп.
    1 %
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    Таблетки Сева Экзекан, 140 г, 16шт. в уп., 1уп.
    Рейтинг товара: 5.0 из 5на основе 50 оценок
      , 
    Цена 1 523 ₽
    Пэй
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  • Кортаванс д/нар.прим.
    15 %
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    Кортаванс д/нар.прим.
    Рейтинг товара: 5.0 из 5на основе 9 оценок
      , 
    Цена 6 435 ₽
    Пэй
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  • Таблетки Zoetis Римадил Р 20 мг, 20шт. в уп., 1уп., 20 мг
    49 %
    НИЖЕ РЫНКА
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    Таблетки Zoetis Римадил Р 20 мг, 20шт. в уп., 1уп., 20 мг
    Рейтинг товара: 4.7 из 5на основе 10 оценок
      , 
    Цена 557 ₽
    Пэй
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О товаре

Апоквел – инновационный ветеринарный препарат для снятия аллергического зуда и воспаления кожи у собак в возрасте от 12 месяцев и старше, весом более 3-х кг. Препарат применяется для снятия зуда, воспаления и улучшения состояния кожи при атопическом дерматите.
Апоквел не имеет аналогов! Это единственный ветеринарный препарат класса ингибиторов янус-киназ. Препарат действует на клеточном уровне, блокируя рецептор отвечающий за возникновение зуда у собак.
Апоквел не является гормоном, антигистаминным препаратом или циклоспорином.
Собака больше не чешется и спокойна, а врач может продолжать обследование, чтобы выявить причину основного заболевания.
Бренд
Zoetis
Тип препарата
лекарственный препарат
Действующее вещество
оклацитиниб
Форма выпуска
таблетки для перорального применения
Количество в упаковке
20 шт.
Объем
16 мл
Упаковка
банка
Назначение средства
для кожи, при аллергии
Вид животного
кошки, собаки
Возраст животного
взрослые
Минимальный возраст применения
12 мес
Размер животного
крупные породы
Минимальный вес животного
13.5 кг
Максимальный вес животного
80 кг
Страна производства
Италия
Описание средства
овальные таблетки белого или почти белого цвета, покрытые пленочной оболочкой, с разделительной бороздкой посередине и c надписью на обеих сторонах таблетки: L
Фармакологическая группа
относится к лекарственным препаратам группы селективных ингибиторов янус-киназы (JAK)
Фармакологическое действие
Апоквел относится к лекарственным препаратам группы селективных ингибиторов янус-киназы (JAK). Оклацитиниба малеат, входящий в состав препарата, в терапевтической дозе угнетает функции провоспалительных, проаллергических и пруритогенных (зудогенных) цитокинов, зависимых от ферментативной активности янус-киназы JAK1 или JAK3, целенаправленное воздействие на которые позволяет ингибировать ключевые механизмы возникновения зуда, ассоциированного с аллергией, и способствует устранению симптомов местного воспаления; на цитокины, участвующие в кроветворении и зависимые от JAK2, существенно не влияет. При длительном применении в более высоких дозах оклацитиниб может вызывать угнетение лимфоидной ткани, ингибировать активацию Т-клеток посредством подавления сигнала на уровне рецепторов интерлейкинов IL-2, что характеризует фармакологическое действие соединений данного класса. После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью.
Состав
В 1 таблетке в качестве действующего вещества: оклацитиниба малеат (в пересчете на оклацитиниб) 16 мг, вспомогательные вещества: микрокристаллическую целлюлозу, лактозы моногидрат, карбоксиметил-крахмал натрия, магния стеарат, плёнкообразователь «Opadry II White» и воду очищенную.
Показания к применению
АПОКВЕЛ назначают собакам при дерматите, ассоциированном с аллергией (контактный, пищевой, паразитарный) в целях устранения зуда и уменьшения очаговых изменений кожи, а также для профилактики рецидивов атопического дерматита.
Противопоказания
Противопоказанием к применению АПОКВЕЛА является индивидуальная непереносимость животным его компонентов. Не допускается применение препарата собакам, с признаками иммуносупрессии, такими как гиперадренокортицизм, а также собакам, с прогрессирующими злокачественными новообразованиями. Не следует применять препарат кобелям в период вязки, собакам моложе 12-месячного возраста и/или массой менее 3 кг, а также щенным и кормящим сукам.
Побочные действия
Побочные явления и осложнения при кратковременном применении Апоквела могут проявляться угнетенным состоянием, расстройством функции желудочно-кишечного тракта, циститом; у животных, получающих Апоквел более 16 дней, приблизительно в 1% случаев может наблюдаться повышение аппетита и агрессия, кожные и подкожные новообразования, инфекции кожи, вызванные дрожжевыми грибками, увеличением лимфатических узлов, обострением демодекоза и онкологических заболеваний.
Передозировка
При передозировке лекарственного препарата у животного могут наблюдаться следующие симптомы: угнетенное состояние, рвота, диарея, локальные алопеции, утолщение кожной складки, образование струпьев и корочек, межпальцевые кисты, отек конечностей. Специфические антидоты отсутствуют, животному применяют симптоматическое лечение.
Взаимодействие
При совместном применении Апоквела с противомикробными, противовоспалительными и противопаразитарными препаратами фармакологического взаимодействия не выявлено. Не следует применять Апоквел совместно с иммунодепрессантами и противосудорожными препаратами.
Особые указания
Пустые флаконы из-под лекарственного препарата запрещается использовать для бытовых целей, они подлежат утилизации с бытовыми отходами. Особенности действия при первом применении препарата и при его отмене не выявлены. Следует избегать пропусков при введении очередной дозы препарата, так как это может привести к снижению эффективности. В случае пропуска очередной дозы, применение Апоквела возобновляют в соответствии с настоящей инструкцией. Апоквел не предназначен для применения продуктивным животным.
Применение у беременных и кормящих животных
не следует применять сукам в период беременности и лактации
Способ применения и дозы
Апоквел применяют собакам перорально индивидуально с руки, или в смеси с кормом, или вводят принудительно в пасть в разовой дозе 0,4-0,6 мг оклацитиниба на 1 кг массы животного два раза в день, не более 14 суток; в качестве поддерживающей терапии при атопическом дерматите – один раз в сутки в той же дозе, но не более 14 недель. Схема и длительность курса применения препарата зависят от этиологии и патогенеза дерматита, клинического состояния животного и определяются лечащим ветеринарным врачом.
Фармакокинетика
после перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа
Условия отпуска
без рецепта
Условия хранения
Хранят препарат в закрытой упаковке производителя, в сухом, защищенном от света месте, отдельно от продуктов питания и кормов при температуре от 0 °С до 25 °С.
Регистрационный номер
840-3-20.20-4711№ПВИ-3-1.16/04707
Дата государственной регистрации
20.02.2021
Перед покупкой уточняйте характеристики и комплектацию у продавца.
Есть противопоказания, посоветуйтесь с врачом.
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
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Отзывы

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12 оценок•6 отзывов
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4 июня•Имя скрыто•Куплен на Маркете
Достоинства: Оригинал
user avatar
26 мая•Имя скрыто•Куплен на Маркете
review-photo
Достоинства: Таблетки рабочие
Недостатки: Не соответствует карточке товара
user avatar
5 мая•Дарья•Куплен на Маркете
Достоинства: Нет побочных эффектов
Комментарий: На постоянной основе кошка принимает 2 раза в день. Хорошее лекарство
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Вопросы о товаре
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Войдите в аккаунт

И тогда откроется корзина, а цены на Маркете могут стать ниже
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