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Баннер
ЯндексЯндекс
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Апоквел для собак таблетки (Zoetis) 16 мг. 20 шт. в уп.

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Артикул Маркета
103542547964
Тип препарата
Вид животного
Назначение средства
Форма выпуска
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После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью."},{"name":"Фармакологическое действие","value":"Апоквел относится к лекарственным препаратам группы селективных ингибиторов янус-киназы (JAK). Оклацитиниба малеат, входящий в состав препарата, в терапевтической дозе угнетает функции провоспалительных, проаллергических и пруритогенных (зудогенных) цитокинов, зависимых от ферментативной активности янус-киназы JAK1 или JAK3, целенаправленное воздействие на которые позволяет ингибировать ключевые механизмы возникновения зуда, ассоциированного с аллергией, и способствует устранению симптомов местного воспаления; на цитокины, участвующие в кроветворении и зависимые от JAK2, существенно не влияет. При длительном применении в более высоких дозах оклацитиниб может вызывать угнетение лимфоидной ткани, ингибировать активацию Т-клеток посредством подавления сигнала на уровне рецепторов интерлейкинов IL-2, что характеризует фармакологическое действие соединений данного класса. После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью."},{"name":"Состав","value":"в 1 таблетке в качестве действующего вещества оклацитиниба малеат (в пересчете на оклацитиниб) 16 мг, а также вспомогательные вещества: микрокристаллическую целлюлозу, лактозы моногидрат, карбоксиметил-крахмал натрия, магния стеарат, плёнкообразователь «Opadry II White» и воду очищенную."},{"name":"Показания к применению","value":"Апоквел назначают собакам при дерматите, ассоциированном с аллергией (контактный, пищевой, паразитарный) в целях устранения зуда и уменьшения очаговых изменений кожи, а также для профилактики рецидивов атопического дерматита."},{"name":"Противопоказания","value":"Противопоказанием к применению Апоквела является индивидуальная непереносимость животным его компонентов. Не допускается применение препарата собакам, с признаками иммуносупрессии, такими как гиперадренокортицизм, а также собакам, с прогрессирующими злокачественными новообразованиями. Не следует применять препарат кобелям в период вязки, собакам моложе 12-месячного возраста и/или массой менее 3 кг, а также щенным и кормящим сукам."},{"name":"Побочные действия","value":"Побочные явления и осложнения при кратковременном применении Апоквела могут проявляться угнетенным состоянием, расстройством функции желудочно-кишечного тракта, циститом; у животных, получающих Апоквел более 16 дней, приблизительно в 1 % случаев может наблюдаться повышение аппетита и агрессия, кожные и подкожные новообразования, инфекции кожи, вызванные дрожжевыми грибками, увеличением лимфатических узлов, обострением демодекоза и онкологических заболеваний."},{"name":"Передозировка","value":"При передозировке лекарственного препарата у животного могут наблюдаться следующие симптомы: угнетенное состояние, рвота, диарея, локальные алопеции, утолщение кожной складки, образование струпьев и корочек, межпальцевые кисты, отек конечностей. Специфические антидоты отсутствуют, животному применяют симптоматическое лечение."},{"name":"Взаимодействие","value":"При совместном применении Апоквела с противомикробными, противовоспалительными и противопаразитарными препаратами фармакологического взаимодействия не выявлено. Не следует применять Апоквел совместно с иммунодепрессантами и противосудорожными препаратами."},{"name":"Особые указания","value":"Пустые флаконы из-под лекарственного препарата запрещается использовать для бытовых целей, они подлежат утилизации с бытовыми отходами. Особенности действия при первом применении препарата и при его отмене не выявлены. Следует избегать пропусков при введении очередной дозы препарата, так как это может привести к снижению эффективности. В случае пропуска очередной дозы, применение Апоквела возобновляют в соответствии с настоящей инструкцией. Апоквел не предназначен для применения продуктивным животным."},{"name":"Применение у беременных и кормящих животных","value":"не следует применять сукам в период беременности и лактации"},{"name":"Способ применения и дозы","value":"Апоквел применяют собакам перорально индивидуально с руки, или в смеси с кормом, или вводят принудительно в пасть в разовой дозе 0,4-0,6 мг оклацитиниба на 1 кг массы животного два раза в день, не более 14 суток; в качестве поддерживающей терапии при атопическом дерматите – один раз в сутки в той же дозе, но не более 14 недель. 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Оклацитиниба малеат, входящий в состав препарата, в терапевтической дозе угнетает функции провоспалительных, проаллергических и пруритогенных (зудогенных) цитокинов, зависимых от ферментативной активности янус-киназы JAK1 или JAK3, целенаправленное воздействие на которые позволяет ингибировать ключевые механизмы возникновения зуда, ассоциированного с аллергией, и способствует устранению симптомов местного воспаления; на цитокины, участвующие в кроветворении и зависимые от JAK2, существенно не влияет. При длительном применении в более высоких дозах оклацитиниб может вызывать угнетение лимфоидной ткани, ингибировать активацию Т-клеток посредством подавления сигнала на уровне рецепторов интерлейкинов IL-2, что характеризует фармакологическое действие соединений данного класса. После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью."},{"name":"Фармакологическое действие","value":"Апоквел относится к лекарственным препаратам группы селективных ингибиторов янус-киназы (JAK). Оклацитиниба малеат, входящий в состав препарата, в терапевтической дозе угнетает функции провоспалительных, проаллергических и пруритогенных (зудогенных) цитокинов, зависимых от ферментативной активности янус-киназы JAK1 или JAK3, целенаправленное воздействие на которые позволяет ингибировать ключевые механизмы возникновения зуда, ассоциированного с аллергией, и способствует устранению симптомов местного воспаления; на цитокины, участвующие в кроветворении и зависимые от JAK2, существенно не влияет. При длительном применении в более высоких дозах оклацитиниб может вызывать угнетение лимфоидной ткани, ингибировать активацию Т-клеток посредством подавления сигнала на уровне рецепторов интерлейкинов IL-2, что характеризует фармакологическое действие соединений данного класса. После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью."},{"name":"Состав","value":"в 1 таблетке в качестве действующего вещества оклацитиниба малеат (в пересчете на оклацитиниб) 16 мг, а также вспомогательные вещества: микрокристаллическую целлюлозу, лактозы моногидрат, карбоксиметил-крахмал натрия, магния стеарат, плёнкообразователь «Opadry II White» и воду очищенную."}]},{"name":"Показания и противопоказания","items":[{"name":"Показания к применению","value":"Апоквел назначают собакам при дерматите, ассоциированном с аллергией (контактный, пищевой, паразитарный) в целях устранения зуда и уменьшения очаговых изменений кожи, а также для профилактики рецидивов атопического дерматита."},{"name":"Противопоказания","value":"Противопоказанием к применению Апоквела является индивидуальная непереносимость животным его компонентов. Не допускается применение препарата собакам, с признаками иммуносупрессии, такими как гиперадренокортицизм, а также собакам, с прогрессирующими злокачественными новообразованиями. Не следует применять препарат кобелям в период вязки, собакам моложе 12-месячного возраста и/или массой менее 3 кг, а также щенным и кормящим сукам."},{"name":"Побочные действия","value":"Побочные явления и осложнения при кратковременном применении Апоквела могут проявляться угнетенным состоянием, расстройством функции желудочно-кишечного тракта, циститом; у животных, получающих Апоквел более 16 дней, приблизительно в 1 % случаев может наблюдаться повышение аппетита и агрессия, кожные и подкожные новообразования, инфекции кожи, вызванные дрожжевыми грибками, увеличением лимфатических узлов, обострением демодекоза и онкологических заболеваний."},{"name":"Передозировка","value":"При передозировке лекарственного препарата у животного могут наблюдаться следующие симптомы: угнетенное состояние, рвота, диарея, локальные алопеции, утолщение кожной складки, образование струпьев и корочек, межпальцевые кисты, отек конечностей. Специфические антидоты отсутствуют, животному применяют симптоматическое лечение."},{"name":"Взаимодействие","value":"При совместном применении Апоквела с противомикробными, противовоспалительными и противопаразитарными препаратами фармакологического взаимодействия не выявлено. Не следует применять Апоквел совместно с иммунодепрессантами и противосудорожными препаратами."},{"name":"Особые указания","value":"Пустые флаконы из-под лекарственного препарата запрещается использовать для бытовых целей, они подлежат утилизации с бытовыми отходами. Особенности действия при первом применении препарата и при его отмене не выявлены. Следует избегать пропусков при введении очередной дозы препарата, так как это может привести к снижению эффективности. В случае пропуска очередной дозы, применение Апоквела возобновляют в соответствии с настоящей инструкцией. Апоквел не предназначен для применения продуктивным животным."},{"name":"Применение у беременных и кормящих животных","value":"не следует применять сукам в период беременности и лактации"},{"name":"Способ применения и дозы","value":"Апоквел применяют собакам перорально индивидуально с руки, или в смеси с кормом, или вводят принудительно в пасть в разовой дозе 0,4-0,6 мг оклацитиниба на 1 кг массы животного два раза в день, не более 14 суток; в качестве поддерживающей терапии при атопическом дерматите – один раз в сутки в той же дозе, но не более 14 недель. Схема и длительность курса применения препарата зависят от этиологии и патогенеза дерматита, клинического состояния животного и определяются лечащим ветеринарным врачом."},{"name":"Фармакокинетика","value":"после перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа"}]},{"name":"Условия отпуска и хранения","items":[{"name":"Условия отпуска","value":"без рецепта"},{"name":"Условия хранения","value":"Хранят препарат в закрытой упаковке производителя, в защищенном от прямых солнечных лучей месте, отдельно от продуктов питания и кормов при температуре от 2 ͦС до 25 ͦС."}]},{"name":"Дополнительно","items":[{"name":"Регистрационный номер","value":"840-3-20.20-4711№ПВИ-3-1.16/04707"},{"name":"Дата государственной регистрации","value":"20.02.2021"},{"name":"Дозировка","value":" 16"},{"name":"Комплектация","value":" 20 таблеток"},{"name":"Название серии","value":" Апоквел"},{"name":"Размер животного","value":" Крупный, Малый, Средний"},{"name":"Рецепт","value":" Без рецепта"}]}],"transitionId":"tr_4829330236409264501"}}}}
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Пэй
 
12 500 ₽
 
–29%
без карты
 
8 990 ₽
 
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Таблетки Zoetis Апоквел 16 мг
Апоквел для собак таблетки (Zoetis) 16 мг. 20 шт. в уп.
12 вопросов
Цена с картой Яндекс Пэй:8 900 ₽
Скидка: 29%
–29 %
Вместо:
8 990 ₽12 500 ₽
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Войдите, и станет дешевлеВ аккаунте больше скидок
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ЗооФармацевтика
ЗооФармацевтика
Магазин•4.8 1.4K оценок
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Доставка Маркета
11 июн, по клику  0 ₽
Москва
11 июн, пункт выдачи  0 ₽
Москва
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  • Апоквел для собак таблетки (Zoetis) 16 мг. 20 шт. в уп.
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    Апоквел для собак таблетки (Zoetis) 16 мг. 20 шт. в уп.
    Рейтинг товара: 4.7 из 5на основе 12 оценок
      , 
    Цена 7 029 ₽
    Пэй
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  • Таблетки Zoetis Апоквел, 16 мг, 16 мл, 20шт. в уп., 1уп.
    8 %
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    Таблетки Zoetis Апоквел, 16 мг, 16 мл, 20шт. в уп., 1уп.
    Рейтинг товара: 4.8 из 5на основе 146 оценок
      , 
    Цена 7 326 ₽
    Пэй
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  • Таблетки Zoetis Апоквел, 3.6 мг, 25 г, 20шт. в уп., 1уп.
    1 %
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    Таблетки Zoetis Апоквел, 3.6 мг, 25 г, 20шт. в уп., 1уп.
    Рейтинг товара: 4.9 из 5на основе 122 оценки
      , 
    Цена 3 020 ₽
    Пэй
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  • Таблетки Zoetis Апоквел, 16 мг, 100 мл, 100 г, 100шт. в уп., 1уп., 16 мг
    19 %
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    Таблетки Zoetis Апоквел, 16 мг, 100 мл, 100 г, 100шт. в уп., 1уп., 16 мг
    Рейтинг товара: 4.6 из 5на основе 9 оценок
      , 
    Цена 39 501 ₽
    Пэй
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  • Таблетки Zoetis Апоквел, 5.4 мг, 26 г, 20шт. в уп., 1уп.
    26 %
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    Таблетки Zoetis Апоквел, 5.4 мг, 26 г, 20шт. в уп., 1уп.
    Рейтинг товара: 4.9 из 5на основе 40 оценок
      , 
    Цена 4 037 ₽
    Пэй
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  • Таблетки Zoetis Апоквел, 5.4 мг, 20шт. в уп., 1уп.
    45 %
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    Таблетки Zoetis Апоквел, 5.4 мг, 20шт. в уп., 1уп.
    Рейтинг товара: 4.6 из 5на основе 104 оценки
      , 
    Цена 4 153 ₽
    Пэй
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  • Таблетки Boehringer Ingelheim Превикокс (Previcox) 227 мг, 227 мл, 20 г, 10шт. в уп., 1уп., 227 мг
    38 %
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    Таблетки Boehringer Ingelheim Превикокс (Previcox) 227 мг, 227 мл, 20 г, 10шт. в уп., 1уп., 227 мг
    Рейтинг товара: 4.8 из 5на основе 219 оценок
      , 
    Цена 3 835 ₽
    Пэй
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  • Таблетки Ceva Экзекан 1 мг/10 мг/50 мг/300 мг, 149 г, 16шт. в уп., 1уп.
    1 %
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    Таблетки Ceva Экзекан 1 мг/10 мг/50 мг/300 мг, 149 г, 16шт. в уп., 1уп.
    Рейтинг товара: 4.8 из 5на основе 283 оценки
      , 
    Цена 1 486 ₽
    Пэй
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  • Таблетки Сева Экзекан, 140 г, 16шт. в уп., 1уп.
    1 %
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    Таблетки Сева Экзекан, 140 г, 16шт. в уп., 1уп.
    Рейтинг товара: 5.0 из 5на основе 49 оценок
      , 
    Цена 1 523 ₽
    Пэй
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  • Таблетки Zoetis Трококсил, 20 мг, 20 мл, 40 г, 2шт. в уп., 1уп., 20 мг
    50 %
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    Таблетки Zoetis Трококсил, 20 мг, 20 мл, 40 г, 2шт. в уп., 1уп., 20 мг
    Рейтинг товара: 5.0 из 5на основе 1 оценка
      , 
    Цена 9 900 ₽
    Пэй
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  • Таблетки Zoetis Трококсил, 95 мг, 10 г, 2шт. в уп., 1уп.
    44 %
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    Таблетки Zoetis Трококсил, 95 мг, 10 г, 2шт. в уп., 1уп.
    Рейтинг товара: 5.0 из 5на основе 4 оценки
      , 
    Цена 16 830 ₽
    Пэй
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  • Спрей Ветфарм Кортавет, 80 мл
    1 %
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    Спрей Ветфарм Кортавет, 80 мл
    Рейтинг товара: 4.6 из 5на основе 573 оценки
      , 
    Цена 2 079 ₽
    Пэй
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О товаре

Апоквел для снятия зуда и воспаления при дерматитах. Апоквел (оклацитиниб) - новый лекарственный препарат. Апоквел предназначен для снятия симптома зуда при аллергических дерматитах у собак в возрасте от 12 месяцев и старше. Апоквел устраняет зуд, независимо от его причины, снижает воспаление и отек. Апоквел действует быстро и эффективно! Что такое Апоквел: Апоквел (оклацитиниб) - новый лекарственный препарат. Апоквел предназначен для снятия симптома зуда при аллергических дерматитах у собак в возрасте от 12 месяцев и старше. Апоквел устраняет зуд, независимо от его причины, снижает воспаление и отек. Апоквел в отличии от преднизолона, не влияет на результаты аллергических и серологических тестов. Апоквел позволяет проводить вакцинацию в ходе лечения. Апоквел действует быстро и эффективно в течении 4-х часов! Во время лечения можно с безопасностью применять эндо- и экзопаразитициды, антимикробные и противовоспалительные препараты Апоквел безопасен при длительном применении. Апоквел не вызывает побочных эффектов по сравнению со стероидами, циклоспоринами и антигистаминными препаратами. Апоквел безопасно применять с другими препаратами – он не снижает их эффективности. Внимание! Апоквел снимает зуд. Ваша собака перестает чесаться, но! Важно определить и ликвидировать причину заболевания вашего питомца, подобрать правильное лечение и рацион! Обязательно проконсультируйтесь с Вашим ветеринарным врачом перед применением препарата! Применение: Апоквел можно применять в случае острой, сезонной и хронической аллергии , а так же при атопическом дерматите. В случае острой и краткосрочной сезонной аллергии Апоквел применяют по 1 таблетке 2 раза в день 14 дней подряд. В случае если необходимо длительное лечение (хронические или длительные сезонные аллергии и атопический дерматит), начиная с 15 дня лечения Апоквел применяют по 1 таблетке в день! Пища не влияет на всасывание Апоквела. Вы можете давать препарат самостоятельно или с кормом. Ограничения в применении: Не применять у собак в возрасте до 1 года Не применять у животных весом менее 3х кг Не применять во время вязки Не применять у беременных и лактирующих животных Не применять у животных с раковыми опухолями Не рекомендуется назначать животным с паразитарными инвазиями без предварительного лечения.
Бренд
Zoetis
Тип препарата
лекарственный препарат
Действующее вещество
оклацитиниб
Форма выпуска
таблетки для перорального применения
Количество в упаковке
20 шт.
Объем
16 мл
Вес
100 г
Упаковка
коробка
Назначение средства
для кожи, при аллергии, Для собак, От аллергии, Спасательные, мультивитамины
Вид животного
кошки, собаки
Возраст животного
взрослые, все возрасты, молодые, пожилые
Минимальный возраст применения
12 мес
Минимальный вес животного
13.5 кг
Максимальный вес животного
80 кг
Страна производства
Италия
Описание средства
овальные таблетки белого или почти белого цвета, покрытые пленочной оболочкой, с разделительной бороздкой посередине и c надписью на обеих сторонах таблетки: L
Фармакологическая группа
Фармакотерапевтическая группа: лекарственный препарат группы селективных ингибиторов янус-киназы (JAK). Оклацитиниба малеат, входящий в состав препарата, в терапевтической дозе угнетает функции провоспалительных, проаллергических и пруритогенных (зудогенных) цитокинов, зависимых от ферментативной активности янус-киназы JAK1 или JAK3, целенаправленное воздействие на которые позволяет ингибировать ключевые механизмы возникновения зуда, ассоциированного с аллергией, и способствует устранению симптомов местного воспаления; на цитокины, участвующие в кроветворении и зависимые от JAK2, существенно не влияет. При длительном применении в более высоких дозах оклацитиниб может вызывать угнетение лимфоидной ткани, ингибировать активацию Т-клеток посредством подавления сигнала на уровне рецепторов интерлейкинов IL-2, что характеризует фармакологическое действие соединений данного класса. После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью.
Фармакологическое действие
Апоквел относится к лекарственным препаратам группы селективных ингибиторов янус-киназы (JAK). Оклацитиниба малеат, входящий в состав препарата, в терапевтической дозе угнетает функции провоспалительных, проаллергических и пруритогенных (зудогенных) цитокинов, зависимых от ферментативной активности янус-киназы JAK1 или JAK3, целенаправленное воздействие на которые позволяет ингибировать ключевые механизмы возникновения зуда, ассоциированного с аллергией, и способствует устранению симптомов местного воспаления; на цитокины, участвующие в кроветворении и зависимые от JAK2, существенно не влияет. При длительном применении в более высоких дозах оклацитиниб может вызывать угнетение лимфоидной ткани, ингибировать активацию Т-клеток посредством подавления сигнала на уровне рецепторов интерлейкинов IL-2, что характеризует фармакологическое действие соединений данного класса. После перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа. Апоквел по степени воздействия на организм относится к веществам умеренно опасным (3 класс опасности по ГОСТ 12.1.007) со слабо выраженными кумулятивными свойствами, в рекомендуемой дозе не обладает мутагенной, канцерогенной, эмбриотоксической и тератогенной активностью.
Состав
в 1 таблетке в качестве действующего вещества оклацитиниба малеат (в пересчете на оклацитиниб) 16 мг, а также вспомогательные вещества: микрокристаллическую целлюлозу, лактозы моногидрат, карбоксиметил-крахмал натрия, магния стеарат, плёнкообразователь «Opadry II White» и воду очищенную.
Показания к применению
Апоквел назначают собакам при дерматите, ассоциированном с аллергией (контактный, пищевой, паразитарный) в целях устранения зуда и уменьшения очаговых изменений кожи, а также для профилактики рецидивов атопического дерматита.
Противопоказания
Противопоказанием к применению Апоквела является индивидуальная непереносимость животным его компонентов. Не допускается применение препарата собакам, с признаками иммуносупрессии, такими как гиперадренокортицизм, а также собакам, с прогрессирующими злокачественными новообразованиями. Не следует применять препарат кобелям в период вязки, собакам моложе 12-месячного возраста и/или массой менее 3 кг, а также щенным и кормящим сукам.
Побочные действия
Побочные явления и осложнения при кратковременном применении Апоквела могут проявляться угнетенным состоянием, расстройством функции желудочно-кишечного тракта, циститом; у животных, получающих Апоквел более 16 дней, приблизительно в 1 % случаев может наблюдаться повышение аппетита и агрессия, кожные и подкожные новообразования, инфекции кожи, вызванные дрожжевыми грибками, увеличением лимфатических узлов, обострением демодекоза и онкологических заболеваний.
Передозировка
При передозировке лекарственного препарата у животного могут наблюдаться следующие симптомы: угнетенное состояние, рвота, диарея, локальные алопеции, утолщение кожной складки, образование струпьев и корочек, межпальцевые кисты, отек конечностей. Специфические антидоты отсутствуют, животному применяют симптоматическое лечение.
Взаимодействие
При совместном применении Апоквела с противомикробными, противовоспалительными и противопаразитарными препаратами фармакологического взаимодействия не выявлено. Не следует применять Апоквел совместно с иммунодепрессантами и противосудорожными препаратами.
Особые указания
Пустые флаконы из-под лекарственного препарата запрещается использовать для бытовых целей, они подлежат утилизации с бытовыми отходами. Особенности действия при первом применении препарата и при его отмене не выявлены. Следует избегать пропусков при введении очередной дозы препарата, так как это может привести к снижению эффективности. В случае пропуска очередной дозы, применение Апоквела возобновляют в соответствии с настоящей инструкцией. Апоквел не предназначен для применения продуктивным животным.
Применение у беременных и кормящих животных
не следует применять сукам в период беременности и лактации
Способ применения и дозы
Апоквел применяют собакам перорально индивидуально с руки, или в смеси с кормом, или вводят принудительно в пасть в разовой дозе 0,4-0,6 мг оклацитиниба на 1 кг массы животного два раза в день, не более 14 суток; в качестве поддерживающей терапии при атопическом дерматите – один раз в сутки в той же дозе, но не более 14 недель. Схема и длительность курса применения препарата зависят от этиологии и патогенеза дерматита, клинического состояния животного и определяются лечащим ветеринарным врачом.
Фармакокинетика
после перорального введения препарата оклацитиниба малеат быстро всасывается в желудочно-кишечном тракте (биодоступность составляет 89 %), поступает в системный кровоток, достигая максимальной концентрации в плазме менее чем через 1 час, проникает в большинство органов и тканей, практически не метаболизируется, выводится из организма в неизмененной форме, преимущественно с мочой, период полувыведения составляет 3-4 часа
Условия отпуска
без рецепта
Условия хранения
Хранят препарат в закрытой упаковке производителя, в защищенном от прямых солнечных лучей месте, отдельно от продуктов питания и кормов при температуре от 2 ͦС до 25 ͦС.
Регистрационный номер
840-3-20.20-4711№ПВИ-3-1.16/04707
Дата государственной регистрации
20.02.2021
Дозировка
16
Комплектация
20 таблеток
Название серии
Апоквел
Размер животного
Крупный, Малый, Средний
Рецепт
Без рецепта
Перед покупкой уточняйте характеристики и комплектацию у продавца.
Есть противопоказания, посоветуйтесь с врачом.
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
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Отзывы

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12 оценок•3 отзыва
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user avatar
3 сентября 2024•Ann B•Куплен на Маркете
Достоинства: Единственное, что реально помогает
Недостатки: цена конечно, но другой видимо не будет
user avatar
19 сентября 2024•Анна Бубнова•Куплен на Маркете
Комментарий: оригинал, работает!
user avatar
2 сентября 2024•Вадим Костенко•Куплен на Маркете
Комментарий: Очень хорошие таблетки, нам помогли. Дороговаты.
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Вопросы о товаре
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Войдите в аккаунт

И тогда откроется корзина, а цены на Маркете могут стать ниже
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