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Описание
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Эспа-Нац пор. д/приг. р-ра д/вн. приема, 600 мг, 20 шт.

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Артикул Маркета
103543313063
Тип препарата
Назначение
Действующее вещество
Форма выпуска
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бронхоэктатическая болезнь, бронхиальная астма, хроническая обструктивная болезнь легких (ХОБЛ), бронхиолиты;- муковисцидоз.Острые и хронические синуситы, воспаление среднего уха (средний отит)."},{"name":"Противопоказания","value":"- Повышенная чувствительность к ацетилцистеину или другим компонентам препарата;- язвенная болезнь желудка и двенадцатиперстной кишки в стадии обострения;- кровохарканье, легочное кровотечение;- дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция (препарат содержит сахарозу);- беременность;- период лактации;- детский возраст до 2 лет (для дозировки 200 мг), детский возраст до 14 лет (для дозировки 600 мг)."},{"name":"Состав","value":"для дозировки 200 мг1 пакетик содержит: активное вещество: ацетилцистеин - 200,0 мг;вспомогательные вещества: сахароза - 2744,10 мг, ароматизатор апельсиновый - 50,0 мг, кремния диоксид коллоидный - 3,00 мг, винная кислота - 2,00 мг, натрия хлорид - 0,90 мг.для дозировки 600 мг1 пакетик содержит: активное вещество: ацетилцистеин - 600,0 мг;вспомогательные вещества: сахароза - 2344,10 мг, ароматизатор апельсиновый - 50,0 мг, кремния диоксид коллоидный - 3,00 мг, винная кислота - 2,00 мг, натрия хлорид - 0,90 мг."},{"value":"Ацетилцистеин","transition":{"params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","navnodeId":"72456","glfilters":["27144131:28708568"],"categoryId":"15756357"},"type":"catalog"},"name":"Действующее вещество"},{"name":"Способ применения и дозы","value":"При отсутствии других назначений следует придерживаться следующих рекомендаций. Порошок растворяют в 1 стакане горячей воды, принимают внутрь после еды.Взрослые и дети старше 14 лет: 2-3 раза в день по 1 пакетику (400-600 мг).Дети от 6 до 14 лет: 2 раза в день по 1 пакетику (400 мг).Дети от 2 до 6 лет: 2-3 раза в день по 1/2 пакетика (200-300 мг).При муковисцидозе: Дети от 2 до 6 лет: 2 раза в день по 1 пакетику (400 мг).Дети старше 6 лет: 3 раза в день по 1 пакетику (600 мг)."},{"name":"Побочные действия","value":"По данным Всемирной организации здравоохранения (ВОЗ) нежелательные эффекты классифицированы в соответствии с их частотой развития следующим образом: очень часто (≥ 1/10), часто (≥ 1/100, <1/10), нечасто (≥ 1/1000, <1/100), редко (≥ 1/10000, <1/1000) и очень редко (< 1/10000); частота неизвестна (частоту возникновения явлений нельзя определить на основании имеющихся данных).Со стороны сердечно-сосудистой системы: редко - снижение артериального давления, увеличение частоты сердечных сокращений (тахикардия).Со стороны дыхательной системы: очень редко - развитие легочного кровотечения, как проявление реакции повышенной чувствительности.Аллергические реакции: редко - бронхоспазм (преимущественно у пациентов с гиперреактивной бронхиальной системой при бронхиальной астме), кожная сыпь, зуд и крапивница, экзантема, ангионевртический отек; очень редко - анафилактические реакции вплоть до развития анафилактического шока, синдром Стивенса-Джонсона, токсический эпидермальный некролиз.Со стороны желудочно-кишечного тракта: редко - стоматит, боли в животе, тошнота, рвота и диарея, изжога, диспепсия.Со стороны органов чувств: нечасто - шум в ушах.Прочие: редко - головная боль, лихорадка, единичные сообщения о развитии кровотечений в связи с наличием реакций повышенной чувствительности, снижение агрегации тромбоцитов."},{"name":"Фармакологическое действие","value":"Муколитическое средство, разжижает мокроту, увеличивает ее объем, облегчает отхождение мокроты. Действие связано со способностью свободных сульфгидрильных групп ацетилцистеина разрывать внутри- и межмолекулярные дисульфидные связи мукополисахаридных цепей, что приводит к деполимеризации мукопротеидов и уменьшению вязкости мокроты (в ряде случаев это приводит к значительному увеличению объема мокроты, что требует аспирации содержимого бронхов). Сохраняет активность при гнойной мокроте. Не влияет на иммунитет.Увеличивает секрецию менее вязких сиаломуцинов бокаловидными клетками, снижает адгезию бактерий на эпителиальных клетках слизистой оболочки бронхов.Стимулирует мукозные клетки бронхов, секрет которых лизирует фибрин.Аналогичное действие оказывает на секрет, образующийся при воспалительных заболеваниях ЛОР-органов.Оказывает антиоксидантное действие, обусловленное наличием SH-группы, способной нейтрализовать электрофильные окислительные токсины.Предохраняет альфа-1-антитрипсин (ингибитор эластазы) от инактивирующего воздействия НОС1 - окислителя, вырабатываемого миелопероксидазой активных фагоцитов.Обладает также некоторым противовоспалительным действием (за счет подавления образования свободных радикалов и активных кислородсодержащих веществ, ответственных за развитие воспаления в легочной ткани).Приводит к повышенному синтезу глютатиона, чем объясняется детоксикационное действие при отравлении парацетамолом.При профилактическом применении ацетилцистеина отмечается уменьшение частоты и тяжести обострений у пациентов с хроническим бронхитом и муковисцидозом."},{"name":"Фармакологическая группа","value":"отхаркивающее муколитическое средство"},{"value":"порошок для приготовления раствора для приема внутрь","transition":{"params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","navnodeId":"72456","glfilters":["27141511:35648767"],"categoryId":"15756357"},"type":"catalog"},"name":"Форма выпуска"},{"value":"пероральный","transition":{"params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","navnodeId":"72456","glfilters":["35947170:36763744"],"categoryId":"15756357"},"type":"catalog"},"name":"Способ применения/введения"},{"name":"Условия хранения","value":"При температуре не выше 25 °С.Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При пероральном применении ацетилцистеина в течение трех месяцев в суточной дозе до 11,6 г не было выявлено опасных для жизни побочных явлений. При пероральном приеме ацетилцистеина в дозе до 500 мг/кг веса тела явлений отравления не наблюдалось.Симптомы: изжога и тошнота, рвота, диарея, боли в желудке. У новорожденных существует опасность развития гиперсекреции.Лечение: симптоматическое."},{"name":"Применение при беременности и кормлении грудью","value":"Данные по применению ацетилцистеина в периоды беременности и грудного вскармливания ограничены, поэтому применение препарата при беременности противопоказано.В случае необходимости применения препарата в период лактации следует решить вопрос о прекращении грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В терапевтических дозах не влияет на способность управлять транспортными средствами и механизмами."},{"name":"Особые указания","value":"Больным с бронхиальной астмой и обструктивным бронхитом ацетилцистеин следует назначать с осторожностью под систематическим контролем бронхиальной проходимости.При растворении препарата необходимо пользоваться стеклянной посудой, избегать контакта с металлами, резиной (при контакте образуются сульфиды с характерным запахом), кислородом, легко окисляющимися веществами.При лечении больных сахарным диабетом необходимо учитывать, что в препарате содержится сахароза (в одном пакетике 600 мг содержится 0,20 ХЕ, соответственно).У пациентов с тяжелыми поражениями кожи - синдромом Стивенса-Джонсона или синдрома Лайелла - в ранней фазе могут появляться температура, боль в теле, ринит, кашель и воспаление горла. При симптоматическом лечении возможно ошибочное назначение муколитических средств. Имеются единичные сообщения (< 1/10000) о выявлении синдрома Стивенса-Джонсона и синдрома Лайелла, совпавшие по времени с назначением препарата; однако причинно-следственная связь с приемом препарата отсутствует. При развитии вышеперечисленных синдромов (внезапное появление сыпи и пятен на лице и туловище, которые позже могут распространиться на другие части тела), рекомендуется прекратить лечение и немедленно обратиться за медицинской помощью."},{"name":"Взаимодействие","value":"При одновременном применении ацетилцистеина и противокашлевых средств может возникнуть застой слизи из-за подавления кашлевого рефлекса.Одновременный прием ацетилцистеина с вазодилятирующими средствами и нитроглицерином может привести к усилению сосудорасширяющего действия последнего.Фармацевтически несовместим с антибиотиками (пенициллинами, цефалоспоринами, эритромицином, тетрациклином и амфотерицином В) и протеолитическими ферментами.Уменьшает всасывание пенициллинов, цефалоспоринов, тетрациклина (их следует принимать не ранее чем через 2 часа после приема внутрь ацетилцистеина)."},{"name":"Регистрационный номер","value":"ЛП-003896"},{"name":"Дата государственной регистрации","value":"11.10.2016"},{"value":"ESPARMA","transition":{"params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","navnodeId":"72456","glfilters":["7893318:12525432"],"categoryId":"15756357"},"type":"catalog"},"name":"Бренд"},{"name":"Изготовитель","value":"Lindopharm"},{"name":"Фасовщик","value":"Lindopharm"},{"name":"Страна бренда","value":"Германия"},{"name":"Страна-производитель","value":"Германия"},{"value":"Эспа-Нац","transition":{"params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","navnodeId":"72456","glfilters":["17796364:17983176"],"categoryId":"15756357"},"type":"catalog"},"name":"Название препарата"},{"name":"Срок годности","value":"48 мес."}]}},"fullSpecsGrouped":{"4097267656449134553":{"groups":[{"name":"Общие характеристики","items":[{"name":"Артикул Маркета","value":"103543313063"},{"value":"ESPARMA","transition":{"params":{"glfilters":["7893318:12525432"]},"type":"catalog"},"name":"Бренд"},{"value":"20 шт.","transition":{"params":{"glfilters":["14805583:20~20"]},"type":"catalog"},"name":"Количество штук в упаковке"},{"value":"лекарственный препарат","transition":{"params":{"glfilters":["34324371:35649313"]},"type":"catalog"},"name":"Тип препарата"},{"value":"бронхи, дыхательная система, легкие","transition":{"params":{"glfilters":["34045610:34516014,34516001,34515990"]},"type":"catalog"},"name":"Органы и системы"},{"value":"бронхиальная астма, бронхиолит, бронхит, бронхоэктатическая болезнь, заболевания дыхательных путей, сопровождающиеся нарушением образования и отхождения мокроты, муковисцидоз, пневмония, синусит, средний отит, трахеит, хроническая обструктивная болезнь легких","transition":{"params":{"glfilters":["36476390:36619067,36619005,36618778,36618522,36618515,36618465,36618448,36617928,36617780,36617343,36617320"]},"type":"catalog"},"name":"Назначение"},{"name":"Показания к применению","value":"Заболевания органов дыхания, сопровождающиеся образованием вязкой трудноотделяемой мокроты:- острые и хронические бронхиты, обструктивный бронхит;- трахеит, ларинготрахеит;- пневмония;- бронхоэктатическая болезнь, бронхиальная астма, хроническая обструктивная болезнь легких (ХОБЛ), бронхиолиты;- муковисцидоз.Острые и хронические синуситы, воспаление среднего уха (средний отит)."},{"name":"Противопоказания","value":"- Повышенная чувствительность к ацетилцистеину или другим компонентам препарата;- язвенная болезнь желудка и двенадцатиперстной кишки в стадии обострения;- кровохарканье, легочное кровотечение;- дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция (препарат содержит сахарозу);- беременность;- период лактации;- детский возраст до 2 лет (для дозировки 200 мг), детский возраст до 14 лет (для дозировки 600 мг)."},{"name":"Состав","value":"для дозировки 200 мг1 пакетик содержит: активное вещество: ацетилцистеин - 200,0 мг;вспомогательные вещества: сахароза - 2744,10 мг, ароматизатор апельсиновый - 50,0 мг, кремния диоксид коллоидный - 3,00 мг, винная кислота - 2,00 мг, натрия хлорид - 0,90 мг.для дозировки 600 мг1 пакетик содержит: активное вещество: ацетилцистеин - 600,0 мг;вспомогательные вещества: сахароза - 2344,10 мг, ароматизатор апельсиновый - 50,0 мг, кремния диоксид коллоидный - 3,00 мг, винная кислота - 2,00 мг, натрия хлорид - 0,90 мг."},{"value":"Ацетилцистеин","transition":{"params":{"glfilters":["27144131:28708568"]},"type":"catalog"},"name":"Действующее вещество"},{"name":"Способ применения и дозы","value":"При отсутствии других назначений следует придерживаться следующих рекомендаций. Порошок растворяют в 1 стакане горячей воды, принимают внутрь после еды.Взрослые и дети старше 14 лет: 2-3 раза в день по 1 пакетику (400-600 мг).Дети от 6 до 14 лет: 2 раза в день по 1 пакетику (400 мг).Дети от 2 до 6 лет: 2-3 раза в день по 1/2 пакетика (200-300 мг).При муковисцидозе: Дети от 2 до 6 лет: 2 раза в день по 1 пакетику (400 мг).Дети старше 6 лет: 3 раза в день по 1 пакетику (600 мг)."},{"name":"Побочные действия","value":"По данным Всемирной организации здравоохранения (ВОЗ) нежелательные эффекты классифицированы в соответствии с их частотой развития следующим образом: очень часто (≥ 1/10), часто (≥ 1/100, <1/10), нечасто (≥ 1/1000, <1/100), редко (≥ 1/10000, <1/1000) и очень редко (< 1/10000); частота неизвестна (частоту возникновения явлений нельзя определить на основании имеющихся данных).Со стороны сердечно-сосудистой системы: редко - снижение артериального давления, увеличение частоты сердечных сокращений (тахикардия).Со стороны дыхательной системы: очень редко - развитие легочного кровотечения, как проявление реакции повышенной чувствительности.Аллергические реакции: редко - бронхоспазм (преимущественно у пациентов с гиперреактивной бронхиальной системой при бронхиальной астме), кожная сыпь, зуд и крапивница, экзантема, ангионевртический отек; очень редко - анафилактические реакции вплоть до развития анафилактического шока, синдром Стивенса-Джонсона, токсический эпидермальный некролиз.Со стороны желудочно-кишечного тракта: редко - стоматит, боли в животе, тошнота, рвота и диарея, изжога, диспепсия.Со стороны органов чувств: нечасто - шум в ушах.Прочие: редко - головная боль, лихорадка, единичные сообщения о развитии кровотечений в связи с наличием реакций повышенной чувствительности, снижение агрегации тромбоцитов."},{"name":"Фармакологическое действие","value":"Муколитическое средство, разжижает мокроту, увеличивает ее объем, облегчает отхождение мокроты. Действие связано со способностью свободных сульфгидрильных групп ацетилцистеина разрывать внутри- и межмолекулярные дисульфидные связи мукополисахаридных цепей, что приводит к деполимеризации мукопротеидов и уменьшению вязкости мокроты (в ряде случаев это приводит к значительному увеличению объема мокроты, что требует аспирации содержимого бронхов). Сохраняет активность при гнойной мокроте. Не влияет на иммунитет.Увеличивает секрецию менее вязких сиаломуцинов бокаловидными клетками, снижает адгезию бактерий на эпителиальных клетках слизистой оболочки бронхов.Стимулирует мукозные клетки бронхов, секрет которых лизирует фибрин.Аналогичное действие оказывает на секрет, образующийся при воспалительных заболеваниях ЛОР-органов.Оказывает антиоксидантное действие, обусловленное наличием SH-группы, способной нейтрализовать электрофильные окислительные токсины.Предохраняет альфа-1-антитрипсин (ингибитор эластазы) от инактивирующего воздействия НОС1 - окислителя, вырабатываемого миелопероксидазой активных фагоцитов.Обладает также некоторым противовоспалительным действием (за счет подавления образования свободных радикалов и активных кислородсодержащих веществ, ответственных за развитие воспаления в легочной ткани).Приводит к повышенному синтезу глютатиона, чем объясняется детоксикационное действие при отравлении парацетамолом.При профилактическом применении ацетилцистеина отмечается уменьшение частоты и тяжести обострений у пациентов с хроническим бронхитом и муковисцидозом."},{"name":"Фармакологическая группа","value":"отхаркивающее муколитическое средство"},{"value":"порошок для приготовления раствора для приема внутрь","transition":{"params":{"glfilters":["27141511:35648767"]},"type":"catalog"},"name":"Форма выпуска"},{"value":"пероральный","transition":{"params":{"glfilters":["35947170:36763744"]},"type":"catalog"},"name":"Способ применения/введения"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С.Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При пероральном применении ацетилцистеина в течение трех месяцев в суточной дозе до 11,6 г не было выявлено опасных для жизни побочных явлений. При пероральном приеме ацетилцистеина в дозе до 500 мг/кг веса тела явлений отравления не наблюдалось.Симптомы: изжога и тошнота, рвота, диарея, боли в желудке. У новорожденных существует опасность развития гиперсекреции.Лечение: симптоматическое."},{"name":"Применение при беременности и кормлении грудью","value":"Данные по применению ацетилцистеина в периоды беременности и грудного вскармливания ограничены, поэтому применение препарата при беременности противопоказано.В случае необходимости применения препарата в период лактации следует решить вопрос о прекращении грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В терапевтических дозах не влияет на способность управлять транспортными средствами и механизмами."},{"name":"Особые указания","value":"Больным с бронхиальной астмой и обструктивным бронхитом ацетилцистеин следует назначать с осторожностью под систематическим контролем бронхиальной проходимости.При растворении препарата необходимо пользоваться стеклянной посудой, избегать контакта с металлами, резиной (при контакте образуются сульфиды с характерным запахом), кислородом, легко окисляющимися веществами.При лечении больных сахарным диабетом необходимо учитывать, что в препарате содержится сахароза (в одном пакетике 600 мг содержится 0,20 ХЕ, соответственно).У пациентов с тяжелыми поражениями кожи - синдромом Стивенса-Джонсона или синдрома Лайелла - в ранней фазе могут появляться температура, боль в теле, ринит, кашель и воспаление горла. При симптоматическом лечении возможно ошибочное назначение муколитических средств. Имеются единичные сообщения (< 1/10000) о выявлении синдрома Стивенса-Джонсона и синдрома Лайелла, совпавшие по времени с назначением препарата; однако причинно-следственная связь с приемом препарата отсутствует. При развитии вышеперечисленных синдромов (внезапное появление сыпи и пятен на лице и туловище, которые позже могут распространиться на другие части тела), рекомендуется прекратить лечение и немедленно обратиться за медицинской помощью."},{"name":"Взаимодействие","value":"При одновременном применении ацетилцистеина и противокашлевых средств может возникнуть застой слизи из-за подавления кашлевого рефлекса.Одновременный прием ацетилцистеина с вазодилятирующими средствами и нитроглицерином может привести к усилению сосудорасширяющего действия последнего.Фармацевтически несовместим с антибиотиками (пенициллинами, цефалоспоринами, эритромицином, тетрациклином и амфотерицином В) и протеолитическими ферментами.Уменьшает всасывание пенициллинов, цефалоспоринов, тетрациклина (их следует принимать не ранее чем через 2 часа после приема внутрь ацетилцистеина)."},{"name":"Регистрационный номер","value":"ЛП-003896"},{"name":"Дата государственной регистрации","value":"11.10.2016"},{"value":"ESPARMA","transition":{"params":{"glfilters":["7893318:12525432"]},"type":"catalog"},"name":"Бренд"},{"name":"Изготовитель","value":"Lindopharm"},{"name":"Фасовщик","value":"Lindopharm"},{"name":"Страна бренда","value":"Германия"},{"name":"Страна-производитель","value":"Германия"},{"value":"Эспа-Нац","transition":{"params":{"glfilters":["17796364:17983176"]},"type":"catalog"},"name":"Название препарата"},{"name":"Срок годности","value":"48 мес."}]}],"transitionId":"tr_3274914221628426841"}},"pharma":{"4097267656449134553":{"isPharma":true,"activeSubstance":"Ацетилцистеин"}}}}
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Эспа-Нац пор. д/приг. р-ра д/вн. приема
Эспа-Нац пор. д/приг. р-ра д/вн. приема, 600 мг, 20 шт.
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Цена с картой Яндекс Пэй:382 ₽
Скидка: 1%
–1 %
Вместо: 386 ₽
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Доставка магазина
382 ₽Пэй
Завтра, курьер  99 ₽
Москва
386 ₽
Завтра, самовывоз из аптеки  0 ₽
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ЗдравСити - сервис заказа и выдачи лекарств
Магазин•4.8 402.1K оценок
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    Ацетилцистеин Канон гран. д/пригот. р-ра д/вн. приема пак., 600 мг, 3 г, 10 шт.
    Рейтинг товара: 4.7 из 5на основе 56 оценок
    , 
    Цена 145 ₽
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  • Эйфа АЦ гран. д/приг. р-ра д/вн. приема пак., 200 мг, 3 г, 20 шт.
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    Рейтинг товара: 4.9 из 5на основе 23 оценки
    , 
    Цена 251 ₽
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  • Мукоцил Солюшн Таблетс таб. дисперг., 600 мг, 10 шт.
    1 %
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    Мукоцил Солюшн Таблетс таб. дисперг., 600 мг, 10 шт.
    Рейтинг товара: 4.9 из 5на основе 18 оценок
    , 
    Цена 161 ₽
    Пэй
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  • Ацц пор. д/приг. р-ра д/вн. приема, 600 мг, 3 г, 6 шт., лимон+мед
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    Ацц пор. д/приг. р-ра д/вн. приема, 600 мг, 3 г, 6 шт., лимон+мед
    Рейтинг товара: 4.8 из 5на основе 123 оценки
    , 
    Цена 151 ₽
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  • Флуимуцил гран. д/приг. р-ра д/вн. приема, 200 мг, 30 шт.
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    Флуимуцил гран. д/приг. р-ра д/вн. приема, 200 мг, 30 шт.
    Рейтинг товара: 4.7 из 5на основе 47 оценок
    , 
    Цена 339 ₽
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  • Флуимуцил таб. шип., 600 мг, 10 шт.
    19 %
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    Флуимуцил таб. шип., 600 мг, 10 шт.
    Рейтинг товара: 4.9 из 5на основе 276 оценок
    , 
    Цена 300 ₽
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  • Пентафлуцин гран. д/приг. р-ра д/вн. приема, 5 г, 10 шт.
    9 %
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    Пентафлуцин гран. д/приг. р-ра д/вн. приема, 5 г, 10 шт.
    Рейтинг товара: 4.9 из 5на основе 67 оценок
    , 
    Цена 260 ₽
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  • АЦЦ Лонг таб. шип., 600 мг, 20 шт.
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    АЦЦ Лонг таб. шип., 600 мг, 20 шт.
    Рейтинг товара: 4.9 из 5на основе 226 оценок
    , 
    Цена 450 ₽
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  • Фенипрекс-С пор. д/приг. р-ра д/вн. приема пак., 5 г, 10 шт., малина
    1 %
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    Фенипрекс-С пор. д/приг. р-ра д/вн. приема пак., 5 г, 10 шт., малина
    Рейтинг товара: 4.6 из 5на основе 53 оценки
    , 
    Цена 176 ₽
    Пэй
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  • Рибавирин таб., 20 шт.
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    Рибавирин таб., 20 шт.
    Рейтинг товара: 5.0 из 5на основе 1 оценка
    , 
    Цена 175 ₽
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  • Сафистон Флю пор. д/приг. р-ра д/вн. прием., 500 мг+25 мг+200 мг, 4.95 г, 10 шт., малина
    1 %
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    Сафистон Флю пор. д/приг. р-ра д/вн. прием., 500 мг+25 мг+200 мг, 4.95 г, 10 шт., малина
    , 
    Цена 511 ₽
    Пэй
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  • Микстура от кашля для взрослых сухая пор. д/приг. р-ра д/вн. приема, 1.7 г, 10 шт.
    1 %
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    Микстура от кашля для взрослых сухая пор. д/приг. р-ра д/вн. приема, 1.7 г, 10 шт.
    , 
    Цена 92 ₽
    Пэй
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Инструкция
Артикул Маркета
103543313063
Бренд
ESPARMA
Количество штук в упаковке
20 шт.
Тип препарата
лекарственный препарат
Органы и системы
бронхи, дыхательная система, легкие
Назначение
бронхиальная астма, бронхиолит, бронхит, бронхоэктатическая болезнь, заболевания дыхательных путей, сопровождающиеся нарушением образования и отхождения мокроты, муковисцидоз, пневмония, синусит, средний отит, трахеит, хроническая обструктивная болезнь легких
Показания к применению
Заболевания органов дыхания, сопровождающиеся образованием вязкой трудноотделяемой мокроты:- острые и хронические бронхиты, обструктивный бронхит;- трахеит, ларинготрахеит;- пневмония;- бронхоэктатическая болезнь, бронхиальная астма, хроническая обструктивная болезнь легких (ХОБЛ), бронхиолиты;- муковисцидоз.Острые и хронические синуситы, воспаление среднего уха (средний отит).
Противопоказания
- Повышенная чувствительность к ацетилцистеину или другим компонентам препарата;- язвенная болезнь желудка и двенадцатиперстной кишки в стадии обострения;- кровохарканье, легочное кровотечение;- дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция (препарат содержит сахарозу);- беременность;- период лактации;- детский возраст до 2 лет (для дозировки 200 мг), детский возраст до 14 лет (для дозировки 600 мг).
Состав
для дозировки 200 мг1 пакетик содержит: активное вещество: ацетилцистеин - 200,0 мг;вспомогательные вещества: сахароза - 2744,10 мг, ароматизатор апельсиновый - 50,0 мг, кремния диоксид коллоидный - 3,00 мг, винная кислота - 2,00 мг, натрия хлорид - 0,90 мг.для дозировки 600 мг1 пакетик содержит: активное вещество: ацетилцистеин - 600,0 мг;вспомогательные вещества: сахароза - 2344,10 мг, ароматизатор апельсиновый - 50,0 мг, кремния диоксид коллоидный - 3,00 мг, винная кислота - 2,00 мг, натрия хлорид - 0,90 мг.
Действующее вещество
Ацетилцистеин
Способ применения и дозы
При отсутствии других назначений следует придерживаться следующих рекомендаций. Порошок растворяют в 1 стакане горячей воды, принимают внутрь после еды.Взрослые и дети старше 14 лет: 2-3 раза в день по 1 пакетику (400-600 мг).Дети от 6 до 14 лет: 2 раза в день по 1 пакетику (400 мг).Дети от 2 до 6 лет: 2-3 раза в день по 1/2 пакетика (200-300 мг).При муковисцидозе: Дети от 2 до 6 лет: 2 раза в день по 1 пакетику (400 мг).Дети старше 6 лет: 3 раза в день по 1 пакетику (600 мг).
Побочные действия
По данным Всемирной организации здравоохранения (ВОЗ) нежелательные эффекты классифицированы в соответствии с их частотой развития следующим образом: очень часто (≥ 1/10), часто (≥ 1/100, <1/10), нечасто (≥ 1/1000, <1/100), редко (≥ 1/10000, <1/1000) и очень редко (< 1/10000); частота неизвестна (частоту возникновения явлений нельзя определить на основании имеющихся данных).Со стороны сердечно-сосудистой системы: редко - снижение артериального давления, увеличение частоты сердечных сокращений (тахикардия).Со стороны дыхательной системы: очень редко - развитие легочного кровотечения, как проявление реакции повышенной чувствительности.Аллергические реакции: редко - бронхоспазм (преимущественно у пациентов с гиперреактивной бронхиальной системой при бронхиальной астме), кожная сыпь, зуд и крапивница, экзантема, ангионевртический отек; очень редко - анафилактические реакции вплоть до развития анафилактического шока, синдром Стивенса-Джонсона, токсический эпидермальный некролиз.Со стороны желудочно-кишечного тракта: редко - стоматит, боли в животе, тошнота, рвота и диарея, изжога, диспепсия.Со стороны органов чувств: нечасто - шум в ушах.Прочие: редко - головная боль, лихорадка, единичные сообщения о развитии кровотечений в связи с наличием реакций повышенной чувствительности, снижение агрегации тромбоцитов.
Фармакологическое действие
Муколитическое средство, разжижает мокроту, увеличивает ее объем, облегчает отхождение мокроты. Действие связано со способностью свободных сульфгидрильных групп ацетилцистеина разрывать внутри- и межмолекулярные дисульфидные связи мукополисахаридных цепей, что приводит к деполимеризации мукопротеидов и уменьшению вязкости мокроты (в ряде случаев это приводит к значительному увеличению объема мокроты, что требует аспирации содержимого бронхов). Сохраняет активность при гнойной мокроте. Не влияет на иммунитет.Увеличивает секрецию менее вязких сиаломуцинов бокаловидными клетками, снижает адгезию бактерий на эпителиальных клетках слизистой оболочки бронхов.Стимулирует мукозные клетки бронхов, секрет которых лизирует фибрин.Аналогичное действие оказывает на секрет, образующийся при воспалительных заболеваниях ЛОР-органов.Оказывает антиоксидантное действие, обусловленное наличием SH-группы, способной нейтрализовать электрофильные окислительные токсины.Предохраняет альфа-1-антитрипсин (ингибитор эластазы) от инактивирующего воздействия НОС1 - окислителя, вырабатываемого миелопероксидазой активных фагоцитов.Обладает также некоторым противовоспалительным действием (за счет подавления образования свободных радикалов и активных кислородсодержащих веществ, ответственных за развитие воспаления в легочной ткани).Приводит к повышенному синтезу глютатиона, чем объясняется детоксикационное действие при отравлении парацетамолом.При профилактическом применении ацетилцистеина отмечается уменьшение частоты и тяжести обострений у пациентов с хроническим бронхитом и муковисцидозом.
Фармакологическая группа
отхаркивающее муколитическое средство
Форма выпуска
порошок для приготовления раствора для приема внутрь
Способ применения/введения
пероральный
Условия хранения
При температуре не выше 25 °С.Хранить в недоступном для детей месте.
Передозировка
При пероральном применении ацетилцистеина в течение трех месяцев в суточной дозе до 11,6 г не было выявлено опасных для жизни побочных явлений. При пероральном приеме ацетилцистеина в дозе до 500 мг/кг веса тела явлений отравления не наблюдалось.Симптомы: изжога и тошнота, рвота, диарея, боли в желудке. У новорожденных существует опасность развития гиперсекреции.Лечение: симптоматическое.
Применение при беременности и кормлении грудью
Данные по применению ацетилцистеина в периоды беременности и грудного вскармливания ограничены, поэтому применение препарата при беременности противопоказано.В случае необходимости применения препарата в период лактации следует решить вопрос о прекращении грудного вскармливания.
Влияние на способность управлять транспортом и механизмами
В терапевтических дозах не влияет на способность управлять транспортными средствами и механизмами.
Особые указания
Больным с бронхиальной астмой и обструктивным бронхитом ацетилцистеин следует назначать с осторожностью под систематическим контролем бронхиальной проходимости.При растворении препарата необходимо пользоваться стеклянной посудой, избегать контакта с металлами, резиной (при контакте образуются сульфиды с характерным запахом), кислородом, легко окисляющимися веществами.При лечении больных сахарным диабетом необходимо учитывать, что в препарате содержится сахароза (в одном пакетике 600 мг содержится 0,20 ХЕ, соответственно).У пациентов с тяжелыми поражениями кожи - синдромом Стивенса-Джонсона или синдрома Лайелла - в ранней фазе могут появляться температура, боль в теле, ринит, кашель и воспаление горла. При симптоматическом лечении возможно ошибочное назначение муколитических средств. Имеются единичные сообщения (< 1/10000) о выявлении синдрома Стивенса-Джонсона и синдрома Лайелла, совпавшие по времени с назначением препарата; однако причинно-следственная связь с приемом препарата отсутствует. При развитии вышеперечисленных синдромов (внезапное появление сыпи и пятен на лице и туловище, которые позже могут распространиться на другие части тела), рекомендуется прекратить лечение и немедленно обратиться за медицинской помощью.
Взаимодействие
При одновременном применении ацетилцистеина и противокашлевых средств может возникнуть застой слизи из-за подавления кашлевого рефлекса.Одновременный прием ацетилцистеина с вазодилятирующими средствами и нитроглицерином может привести к усилению сосудорасширяющего действия последнего.Фармацевтически несовместим с антибиотиками (пенициллинами, цефалоспоринами, эритромицином, тетрациклином и амфотерицином В) и протеолитическими ферментами.Уменьшает всасывание пенициллинов, цефалоспоринов, тетрациклина (их следует принимать не ранее чем через 2 часа после приема внутрь ацетилцистеина).
Регистрационный номер
ЛП-003896
Дата государственной регистрации
11.10.2016
Бренд
ESPARMA
Изготовитель
Lindopharm
Фасовщик
Lindopharm
Страна бренда
Германия
Страна-производитель
Германия
Название препарата
Эспа-Нац
Срок годности
48 мес.
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Полная инструкция
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Отзывы

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Вопросы о товаре
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Войдите в аккаунтИ тогда откроется корзина, а цены на Маркете могут стать ниже
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