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Описание

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Тиоктовая кислота-ВЕРТЕКС таб. п/о плен., 600 мг, 28 шт.

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4.9
(44)
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Коротко о товаре

Артикул Маркета
4453152186
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"9898025339268690060":{"specItems":[{"name":"Артикул Маркета","value":"4453152186","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"алкогольная полинейропатия, диабетическая полинейропатия","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["36476390:36618703,36618693"]}}},{"name":"действующее вещество","value":"Тиоктовая кислота","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28709872"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"таблетки"},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"9898025339268690060":{"specItems":[{"name":"Артикул Маркета","value":"4453152186","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Действующее вещество","value":"Тиоктовая кислота","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28709872"]}}},{"name":"Возраст","value":"От 18 лет"},{"name":"Форма выпуска","value":"Таблетки"}]}},"fullSpecs":{"9898025339268690060":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"кровеносная система","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34045610:34515997"]}}},{"name":"Назначение","value":"алкогольная полинейропатия, диабетическая полинейропатия","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["36476390:36618703,36618693"]}}},{"name":"Показания к применению","value":"- Диабетическая полинейропатия; \u003Cbr /\u003E- алкогольная полинейропатия."},{"name":"Противопоказания","value":"- Повышенная чувствительность к тиоктовой кислоте или к любому другому компоненту препарата; \u003Cbr /\u003E- дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция; \u003Cbr /\u003E- беременность; \u003Cbr /\u003E- период грудного вскармливания (отсутствует достаточный опыт применения препарата); \u003Cbr /\u003E- детский возраст до 18 лет (отсутствуют клинические данные о применении)."},{"name":"Состав","value":"Одна таблетка, покрытая пленочной оболочкой, содержит: \u003Cbr /\u003Eдействующее вещество: тиоктовая кислота (альфа-липоевая кислота) - 600,0 мг; \u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат - 212,0 мг; гипролоза (гидроксипропилцеллюлоза) низкозамещенная - 110,0 мг; целлюлоза микрокристаллическая 102 - 90,0 мг; кремния диоксид коллоидный - 33,0 мг; магния стеарат - 33,0 мг; гипролоза (гидроксипропилцеллюлоза) - 22,0 мг; \u003Cbr /\u003Eпленочная оболочка: [гипромеллоза - 20,000 мг; гипролоза (гидроксипропилцеллюлоза) - 7,760 мг; тальк - 7,704 мг; титана диоксид - 4,348 мг; краситель железа оксид желтый (краситель железа оксид) - 0,188 мг] или [сухая смесь для пленочного покрытия, содержащая гипромеллозу (50%), гипролозу (гидроксипропилцеллюлозу) (19,4%), тальк (19,26%), титана диоксид (10,87%), краситель железа оксид желтый (краситель железа оксид) (0,47%)] - 40,0 мг."},{"name":"Действующее вещество","value":"Тиоктовая кислота","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28709872"]}}},{"name":"Способ применения и дозы","value":"Внутрь, не разжевывая, запивая достаточным количеством воды, за 30 минут до первого приема пищи (натощак). \u003Cbr /\u003EПри диабетической полинейропатии и алкогольной полинейропатии препарат принимают в дозе 600 мг 1 раз в сутки. \u003Cbr /\u003EПри тяжелой диабетической полинейропатии лечение желательно начинать с парентерального введения тиоктовой кислоты в течение 2-4 недель. В дальнейшем следует продолжить лечение пероральным введением препарата в дозе 600 мг 1 раз в сутки."},{"name":"Побочные действия","value":"Классификация частоты развития нежелательных реакций (HP) согласно рекомендациям Всемирной организации здравоохранения (ВОЗ): \u003Cbr /\u003Eочень часто ≥1/10; \u003Cbr /\u003Eчасто от ≥ 1/100 до \u003C 1/10; \u003Cbr /\u003Eнечасто от ≥ 1/1000 до \u003C 1/100; \u003Cbr /\u003Eредко от ≥ 1/10000 до \u003C 1/1000; \u003Cbr /\u003Eочень редко \u003C 1/10000, включая отдельные сообщения; \u003Cbr /\u003Eчастота неизвестна - по имеющимся данным установить частоту возникновения не представляется возможным. \u003Cbr /\u003EНарушения со стороны нервной системы: \u003Cbr /\u003Eчасто - головокружение; \u003Cbr /\u003Eочень редко - изменение или нарушение вкусовых ощущений. \u003Cbr /\u003EЖелудочно-кишечные нарушения: \u003Cbr /\u003Eчасто - тошнота; \u003Cbr /\u003Eочень редко - рвота, боль в животе и гастроинтестинальная боль, диарея. \u003Cbr /\u003EНарушения метаболизма и питания: \u003Cbr /\u003Eочень редко - снижение концентрации глюкозы в крови (из-за улучшения усвоения глюкозы). Сообщалось о жалобах, свидетельствующих о гипогликемическом состоянии, а именно: повышенное потоотделение, головная боль и нарушение зрения. \u003Cbr /\u003EНарушения со стороны иммунной системы: \u003Cbr /\u003Eочень редко - аллергические реакции (вплоть до развития анафилактического шока), кожная сыпь, крапивница (уртикарная сыпь), зуд; \u003Cbr /\u003Eчастота неизвестна - аутоиммунный инсулиновый синдром (АИС), клиническими проявлениями которого могут быть: головокружение, потливость, мышечная дрожь, учащение сердцебиения, тошнота, головная боль, спутанность сознания, нарушение зрительного восприятия, потеря сознания, кома, в условиях наличия аутоантител к инсулину."},{"name":"Фармакологическое действие","value":"Тиоктовая (альфа-липоевая) кислота - эндогенный антиоксидант прямого (связывает свободные радикалы) и непрямого (восстанавливает внутриклеточный уровень глутатиона, повышает активность супероксиддисмутазы) действия. В качестве кофермента митохондриальных мультиферментных комплексов участвует в окислительном декарбоксилировании пировиноградной кислоты и альфа-кетокислот. Способствует снижению содержания глюкозы в плазме крови и увеличению концентрации гликогена в печени, а также снижает инсулинорезистентность.\u003Cbr /\u003E Тиоктовая кислота является эндогенным витаминоподобным веществом и по характеру биохимического действия близка к витаминам группы В. \u003Cbr /\u003EСпособствует защите клетки от токсического действия свободных радикалов, возникающих в процессах обмена веществ; она также обезвреживает экзогенные токсические соединения, проникшие в организм. \u003Cbr /\u003EТиоктовая кислота повышает концентрацию эндогенного антиоксиданта глютатиона, что приводит к уменьшению выраженности симптомов полинейропатии. \u003Cbr /\u003EОказывает гепатопротекторное, гиполипидемическое, гипохолестеринемическое, гипогликемическое действие, улучшает трофику нейронов. \u003Cbr /\u003EРезультатом синергического действия тиоктовой кислоты и инсулина является повышение утилизации глюкозы."},{"name":"Фармакологическая группа","value":"метаболические средства"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить в защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы\u003Cbr /\u003EПри применении очень высоких доз тиоктовой кислоты от 10 до 40 г, могут наблюдаться серьезные признаки интоксикации (генерализованные судорожные припадки, выраженные нарушения кислотно-щелочного баланса, ведущие к лактоацидозу гипогликемическая кома, тяжелые нарушения свертывания крови, приводящие иногда к летальному исходу). \u003Cbr /\u003EПри подозрении на существенную передозировку препарата (дозы, равнозначные более 10 таблеткам для взрослого или более 50 мг/кг массы тела для детей) необходима немедленная госпитализация. \u003Cbr /\u003EЛечение\u003Cbr /\u003EСимптоматическое. При необходимости - противосудорожная терапия, меры по поддержанию функций жизненно важных органов."},{"name":"Применение при беременности и кормлении грудью","value":"Прием тиоктовой кислоты противопоказан во время беременности и в период грудного вскармливания из-за отсутствия достаточного опыта применения."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние приема тиоктовой кислоты на способность управлять транспортными средствами и механизмами не изучалось. Учитывая возможные HP (головокружение и развитие симптомов гипогликемии), необходимо соблюдать осторожность при управлении транспортными средствами и механизмами, а также занятием потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Пациенты с редкой наследственной непереносимостью фруктозы, глюкозо-галактозным синдромом мальабсорбции или глюкозо-изомальтозным дефицитом не должны принимать тиоктовую кислоту.\u003Cbr /\u003EПациентам, принимающим тиоктовую кислоту, следует воздержаться от употребления алкоголя в течение всего курса лечения, а также, по возможности, в перерывах между курсами, поскольку он снижает терапевтическую эффективность препарата и является фактором риска, способствующим развитию и прогрессированию нейропатии.\u003Cbr /\u003EПри развитии гипогликемии необходимо немедленно прекратить прием препарата. \u003Cbr /\u003EПри появлении симптомов повышенной чувствительности необходимо немедленно прекратить прием препарата. При лечении тиоктовой кислотой зарегистрированы случаи АИС. Пациенты с генотипом человеческого лейкоцитарного антигена (аллели HLA- DRB1*04:06 и HLA-DRB1*04:03) более восприимчивы к развитию АИС при лечении тиоктовой кислотой. Аллель HLA-DRB1*04:03 (риск развития АИС выше в 1,6 раза) главным образом встречается у европейцев, чаще в Южной Европе, чем в Северной, и аллель HLA-DRB1*04:06 (риск развития АИС выше в 56,6 раза) чаще встречается у японцев и корейцев. Следует учитывать возможность проявления АИС при дифференциальной диагностике спонтанной гипогликемии у пациентов, принимающих тиоктовую кислоту.\u003Cbr /\u003EУ пациентов с сахарным диабетом необходим постоянный контроль концентрации глюкозы в крови, особенно на начальной стадии терапии. В некоторых случаях необходимо уменьшить дозу инсулина или перорального гипогликемического препарата, чтобы избежать развития гипогликемии."},{"name":"Взаимодействие","value":"При одновременном применении тиоктовой кислоты и цисплатина отмечается снижение эффективности цисплатина. \u003Cbr /Тиоктовая кислота связывает металлы, поэтому ее не следует применять одновременно с препаратами, содержащими металлы (например, препаратами железа, магния, кальция), а также молочными продуктами (из-за содержания в них кальция); интервал между приемом таких препаратов и тиоктовой кислотой должен составлять не менее 2 часов. \u003Cbr /При одновременном применении тиоктовой кислоты и инсулина или пероральных гипогликемических препаратов их действие может усиливаться, поэтому рекомендуется регулярный контроль уровня глюкозы в крови, особенно в начале терапии тиоктовой кислотой. В отдельных случаях допустимо уменьшение дозы гипогликемических препаратов во избежание развития симптомов гипогликемии. \u003Cbr /Этанол и его метаболиты ослабляют действие тиоктовой кислоты."},{"name":"Регистрационный номер","value":"ЛП-005791"},{"name":"Дата государственной регистрации","value":"11.12.2019"},{"name":"Владелец регистрационного удостоверения","value":"Вертекс","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:8514228"]}}},{"name":"Изготовитель","value":"Вертекс"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Тиоктовая кислота","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["17796364:18014576"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"9898025339268690060":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносная система"},{"name":"Назначение","value":"алкогольная полинейропатия, диабетическая полинейропатия"},{"name":"Показания к применению","value":"- Диабетическая полинейропатия; \u003Cbr /\u003E- алкогольная полинейропатия."},{"name":"Противопоказания","value":"- Повышенная чувствительность к тиоктовой кислоте или к любому другому компоненту препарата; \u003Cbr /\u003E- дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция; \u003Cbr /\u003E- беременность; \u003Cbr /\u003E- период грудного вскармливания (отсутствует достаточный опыт применения препарата); \u003Cbr /\u003E- детский возраст до 18 лет (отсутствуют клинические данные о применении)."},{"name":"Состав","value":"Одна таблетка, покрытая пленочной оболочкой, содержит: \u003Cbr /\u003Eдействующее вещество: тиоктовая кислота (альфа-липоевая кислота) - 600,0 мг; \u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат - 212,0 мг; гипролоза (гидроксипропилцеллюлоза) низкозамещенная - 110,0 мг; целлюлоза микрокристаллическая 102 - 90,0 мг; кремния диоксид коллоидный - 33,0 мг; магния стеарат - 33,0 мг; гипролоза (гидроксипропилцеллюлоза) - 22,0 мг; \u003Cbr /\u003Eпленочная оболочка: [гипромеллоза - 20,000 мг; гипролоза (гидроксипропилцеллюлоза) - 7,760 мг; тальк - 7,704 мг; титана диоксид - 4,348 мг; краситель железа оксид желтый (краситель железа оксид) - 0,188 мг] или [сухая смесь для пленочного покрытия, содержащая гипромеллозу (50%), гипролозу (гидроксипропилцеллюлозу) (19,4%), тальк (19,26%), титана диоксид (10,87%), краситель железа оксид желтый (краситель железа оксид) (0,47%)] - 40,0 мг."},{"name":"Действующее вещество","value":"Тиоктовая кислота"},{"name":"Способ применения и дозы","value":"Внутрь, не разжевывая, запивая достаточным количеством воды, за 30 минут до первого приема пищи (натощак). \u003Cbr /\u003EПри диабетической полинейропатии и алкогольной полинейропатии препарат принимают в дозе 600 мг 1 раз в сутки. \u003Cbr /\u003EПри тяжелой диабетической полинейропатии лечение желательно начинать с парентерального введения тиоктовой кислоты в течение 2-4 недель. В дальнейшем следует продолжить лечение пероральным введением препарата в дозе 600 мг 1 раз в сутки."},{"name":"Побочные действия","value":"Классификация частоты развития нежелательных реакций (HP) согласно рекомендациям Всемирной организации здравоохранения (ВОЗ): \u003Cbr /\u003Eочень часто ≥1/10; \u003Cbr /\u003Eчасто от ≥ 1/100 до \u003C 1/10; \u003Cbr /\u003Eнечасто от ≥ 1/1000 до \u003C 1/100; \u003Cbr /\u003Eредко от ≥ 1/10000 до \u003C 1/1000; \u003Cbr /\u003Eочень редко \u003C 1/10000, включая отдельные сообщения; \u003Cbr /\u003Eчастота неизвестна - по имеющимся данным установить частоту возникновения не представляется возможным. \u003Cbr /\u003EНарушения со стороны нервной системы: \u003Cbr /\u003Eчасто - головокружение; \u003Cbr /\u003Eочень редко - изменение или нарушение вкусовых ощущений. \u003Cbr /\u003EЖелудочно-кишечные нарушения: \u003Cbr /\u003Eчасто - тошнота; \u003Cbr /\u003Eочень редко - рвота, боль в животе и гастроинтестинальная боль, диарея. \u003Cbr /\u003EНарушения метаболизма и питания: \u003Cbr /\u003Eочень редко - снижение концентрации глюкозы в крови (из-за улучшения усвоения глюкозы). Сообщалось о жалобах, свидетельствующих о гипогликемическом состоянии, а именно: повышенное потоотделение, головная боль и нарушение зрения. \u003Cbr /\u003EНарушения со стороны иммунной системы: \u003Cbr /\u003Eочень редко - аллергические реакции (вплоть до развития анафилактического шока), кожная сыпь, крапивница (уртикарная сыпь), зуд; \u003Cbr /\u003Eчастота неизвестна - аутоиммунный инсулиновый синдром (АИС), клиническими проявлениями которого могут быть: головокружение, потливость, мышечная дрожь, учащение сердцебиения, тошнота, головная боль, спутанность сознания, нарушение зрительного восприятия, потеря сознания, кома, в условиях наличия аутоантител к инсулину."},{"name":"Фармакологическое действие","value":"Тиоктовая (альфа-липоевая) кислота - эндогенный антиоксидант прямого (связывает свободные радикалы) и непрямого (восстанавливает внутриклеточный уровень глутатиона, повышает активность супероксиддисмутазы) действия. В качестве кофермента митохондриальных мультиферментных комплексов участвует в окислительном декарбоксилировании пировиноградной кислоты и альфа-кетокислот. Способствует снижению содержания глюкозы в плазме крови и увеличению концентрации гликогена в печени, а также снижает инсулинорезистентность.\u003Cbr /\u003E Тиоктовая кислота является эндогенным витаминоподобным веществом и по характеру биохимического действия близка к витаминам группы В. \u003Cbr /\u003EСпособствует защите клетки от токсического действия свободных радикалов, возникающих в процессах обмена веществ; она также обезвреживает экзогенные токсические соединения, проникшие в организм. \u003Cbr /\u003EТиоктовая кислота повышает концентрацию эндогенного антиоксиданта глютатиона, что приводит к уменьшению выраженности симптомов полинейропатии. \u003Cbr /\u003EОказывает гепатопротекторное, гиполипидемическое, гипохолестеринемическое, гипогликемическое действие, улучшает трофику нейронов. \u003Cbr /\u003EРезультатом синергического действия тиоктовой кислоты и инсулина является повышение утилизации глюкозы."},{"name":"Фармакологическая группа","value":"метаболические средства"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить в защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы\u003Cbr /\u003EПри применении очень высоких доз тиоктовой кислоты от 10 до 40 г, могут наблюдаться серьезные признаки интоксикации (генерализованные судорожные припадки, выраженные нарушения кислотно-щелочного баланса, ведущие к лактоацидозу гипогликемическая кома, тяжелые нарушения свертывания крови, приводящие иногда к летальному исходу). \u003Cbr /\u003EПри подозрении на существенную передозировку препарата (дозы, равнозначные более 10 таблеткам для взрослого или более 50 мг/кг массы тела для детей) необходима немедленная госпитализация. \u003Cbr /\u003EЛечение\u003Cbr /\u003EСимптоматическое. При необходимости - противосудорожная терапия, меры по поддержанию функций жизненно важных органов."},{"name":"Применение при беременности и кормлении грудью","value":"Прием тиоктовой кислоты противопоказан во время беременности и в период грудного вскармливания из-за отсутствия достаточного опыта применения."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние приема тиоктовой кислоты на способность управлять транспортными средствами и механизмами не изучалось. Учитывая возможные HP (головокружение и развитие симптомов гипогликемии), необходимо соблюдать осторожность при управлении транспортными средствами и механизмами, а также занятием потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Пациенты с редкой наследственной непереносимостью фруктозы, глюкозо-галактозным синдромом мальабсорбции или глюкозо-изомальтозным дефицитом не должны принимать тиоктовую кислоту.\u003Cbr /\u003EПациентам, принимающим тиоктовую кислоту, следует воздержаться от употребления алкоголя в течение всего курса лечения, а также, по возможности, в перерывах между курсами, поскольку он снижает терапевтическую эффективность препарата и является фактором риска, способствующим развитию и прогрессированию нейропатии.\u003Cbr /\u003EПри развитии гипогликемии необходимо немедленно прекратить прием препарата. \u003Cbr /\u003EПри появлении симптомов повышенной чувствительности необходимо немедленно прекратить прием препарата. При лечении тиоктовой кислотой зарегистрированы случаи АИС. Пациенты с генотипом человеческого лейкоцитарного антигена (аллели HLA- DRB1*04:06 и HLA-DRB1*04:03) более восприимчивы к развитию АИС при лечении тиоктовой кислотой. Аллель HLA-DRB1*04:03 (риск развития АИС выше в 1,6 раза) главным образом встречается у европейцев, чаще в Южной Европе, чем в Северной, и аллель HLA-DRB1*04:06 (риск развития АИС выше в 56,6 раза) чаще встречается у японцев и корейцев. Следует учитывать возможность проявления АИС при дифференциальной диагностике спонтанной гипогликемии у пациентов, принимающих тиоктовую кислоту.\u003Cbr /\u003EУ пациентов с сахарным диабетом необходим постоянный контроль концентрации глюкозы в крови, особенно на начальной стадии терапии. В некоторых случаях необходимо уменьшить дозу инсулина или перорального гипогликемического препарата, чтобы избежать развития гипогликемии."},{"name":"Взаимодействие","value":"При одновременном применении тиоктовой кислоты и цисплатина отмечается снижение эффективности цисплатина. \u003Cbr /Тиоктовая кислота связывает металлы, поэтому ее не следует применять одновременно с препаратами, содержащими металлы (например, препаратами железа, магния, кальция), а также молочными продуктами (из-за содержания в них кальция); интервал между приемом таких препаратов и тиоктовой кислотой должен составлять не менее 2 часов. \u003Cbr /При одновременном применении тиоктовой кислоты и инсулина или пероральных гипогликемических препаратов их действие может усиливаться, поэтому рекомендуется регулярный контроль уровня глюкозы в крови, особенно в начале терапии тиоктовой кислотой. В отдельных случаях допустимо уменьшение дозы гипогликемических препаратов во избежание развития симптомов гипогликемии. \u003Cbr /Этанол и его метаболиты ослабляют действие тиоктовой кислоты."},{"name":"Регистрационный номер","value":"ЛП-005791"},{"name":"Дата государственной регистрации","value":"11.12.2019"},{"name":"Владелец регистрационного удостоверения","value":"Вертекс"},{"name":"Изготовитель","value":"Вертекс"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Тиоктовая кислота"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_3867621630673446069"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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    Цена 415 ₽
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  • Тиогамма таб. п/о плен., 600 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-jlqilc6ee8/toggleWishlist":{"skuId":"227814507","productId":1400799523,"offerId":"LyayekcJC0mnpUGFMGYY_A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQidSXscmfkdxzEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIo4L6mwUQ69jQbBiW4ooRINrZwQc=","sign":"UGfhmQ3mLQABpvaNR2+vTqBan/koawGrJSBHOX3i8fo="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-jlqilc6ee8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тиогамма таб. п/о плен., 600 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 16 оценок
    Цена 990 ₽
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  • Тиоктацид БВ таб. п/о плен., 600 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-tzd0iknyyve/toggleWishlist":{"skuId":"228092173","productId":1400799483,"offerId":"C0v4mnPie5xx3XXoQW_Z7g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQidSXscmfkdxzEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI+4H6mwUQjdLhbBipufkHINrZwQc=","sign":"uM2ObIEgIzdTHssK01+BAz6xJtJopi6uA+fyNIS78YM="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-tzd0iknyyve/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тиоктацид БВ таб. п/о плен., 600 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 22 оценки
    Цена 1 918 ₽
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  • Тиоктовая кислота таб. п/о плен., 300 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vyqp0p0tzh/toggleWishlist":{"skuId":"839526311","productId":1400799779,"offerId":"UwveZU-tDxBY0QvkKfZx1g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQidSXscmfkdxzEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIo4T6mwUQp8+okAMYhKmyCCDa2cEH","sign":"hmQjj6jxdcOM090jUt7sttM37UQoEkgL807YEZMBORw="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vyqp0p0tzh/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тиоктовая кислота таб. п/о плен., 300 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 524 ₽
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  • Октолипен таб. п/о плен., 600 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-15749o4d8y1/toggleWishlist":{"skuId":"650477402","productId":1781572747,"offerId":"frnxcnJLWKOUAhmPe29-Sw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQidSXscmfkdxzEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIi8nC0QYQ2v6VtgIY/sPZByDa2cEH","sign":"MuVxtjCTguGlhwLH9wrwLDN2vhsdWkS15gjIJkUdpx4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-15749o4d8y1/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Октолипен таб. п/о плен., 600 мг, 30 шт.

    Рейтинг товара: 4.4 из 5
    на основе 12 оценок
    Цена 769 ₽
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  • Октолипен капс., 300 мг, 30 шт.
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    Октолипен капс., 300 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 7 оценок
    Цена 411 ₽
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  • Тиоктовая кислота конц. д/приг. р-ра д/инф. амп., 30 мг/мл, 10 мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-0wlfsmsm3rw/toggleWishlist":{"skuId":"265183623","productId":1780857263,"offerId":"RQo6HSTCb8C2-5NU0kkzEw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQidSXscmfkdxzEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIr/OW0QYQh8O5fhiEqbIIINrZwQc=","sign":"38WsTHMSFFB+V3VyffFKvVt/AmpbcibUZd7Z/Qcuyi4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-0wlfsmsm3rw/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тиоктовая кислота конц. д/приг. р-ра д/инф. амп., 30 мг/мл, 10 мл, 10 шт.

    Рейтинг товара: 4.7 из 5
    на основе 20 оценок
    Цена 623 ₽
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  • Пантопразол-Вертекс таб. п/о плен. кш/раств., 20 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-y3ej6njuz4/toggleWishlist":{"skuId":"101520307286","productId":1487470453,"offerId":"5mudUqaGK7UMVQUUY50SXA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQidSXscmfkdxzEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI9f6jxQUQ1ujTmPoCGLTVhwQg2tnBBw==","sign":"UyTBGu9VWzBmuNKZI/iya7+9jmBDvq+cdLjw0HSFYYA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-y3ej6njuz4/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Пантопразол-Вертекс таб. п/о плен. кш/раств., 20 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 9 оценок
    Цена 251 ₽
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  • Тиолипон таб. п/о плен., 300 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gmddyipoerr/toggleWishlist":{"skuId":"265181476","productId":1400799644,"offerId":"tY1nHpNHHi5HNd_TefWhRA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQidSXscmfkdxzEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUInIP6mwUQpLK5fhjo3NAHINrZwQc=","sign":"cU/RMT07FCPH1UVwabd2+qRbV/qe0EVnDSxwL6fqg2E="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gmddyipoerr/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тиолипон таб. п/о плен., 300 мг, 30 шт.

    Рейтинг товара: 4 из 5
    на основе 1 оценка
    Цена 531 ₽
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  • Урсодезоксихолевая кислота-Вертекс капс., 250 мг, 50 шт.
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    Урсодезоксихолевая кислота-Вертекс капс., 250 мг, 50 шт.

    Рейтинг товара: 4.9 из 5
    на основе 18 оценок
    Цена 774 ₽
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Инструкция

Показания к применению

- Диабетическая полинейропатия;
- алкогольная полинейропатия.

Противопоказания

- Повышенная чувствительность к тиоктовой кислоте или к любому другому компоненту препарата;
- дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция;
- беременность;
- период грудного вскармливания (отсутствует достаточный опыт применения препарата);
- детский возраст до 18 лет (отсутствуют клинические данные о применении).

Способ применения и дозы

Внутрь, не разжевывая, запивая достаточным количеством воды, за 30 минут до первого приема пищи (натощак).
При диабетической полинейропатии и алкогольной полинейропатии препарат принимают в дозе 600 мг 1 раз в сутки.
При тяжелой диабетической полинейропатии лечение желательно начинать с парентерального введения тиоктовой кислоты в течение 2-4 недель. В дальнейшем следует продолжить лечение пероральным введением препарата в дозе 600 мг 1 раз в сутки.
Полная инструкция
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Тиоктовая кислота-ВЕРТЕКС таб. п/о плен.
Тиоктовая кислота-ВЕРТЕКС таб. п/о плен., 600 мг, 28 шт.
4.9
(44)
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2 вопроса
Инструкция

663 ₽

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4.9
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У продавца:44 оценки·5 отзывов
У всех продавцов:85 оценок·24 отзыва
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user avatar
2 месяца назад • Марина Трубина • Куплен на Маркете
Недостатки: нет
Комментарий: пришел вовремя, спаибо
user avatar
5 месяцев назад • YURIY G. • Куплен на Маркете
Достоинства: оптимальное цена качество
Недостатки: было бы лучше 30 таблеток
user avatar
4 месяца назад • Лидия Жилина • Куплен на Маркете
Достоинства: цена и качество.
Комментарий: Работает, рекомендую.
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