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Описание

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Тидомет форте таб., 250 мг+25 мг, 100 шт.

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5.0
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Коротко о товаре

Артикул Маркета
3123937549
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Необходимо прекратить применение данных препаратов не менее, чем за 2 недели до начала применения препарата Тидомет Форте (за исключением селективных ингибиторов МАО-В (например, селегилина гидрохлорида)).\u003Cbr\u003EЗакрытоугольная глаукома.\u003Cbr\u003EПациенты с подозрением на недиагностированные кожные заболевания или меланомой в анамнезе (поскольку леводопа может стимулировать развитие злокачественной меланомы).\u003Cbr\u003EТяжелый психоз.\u003Cbr\u003EВозраст до 18 лет (безопасности применения у детей не установлена).\u003Cbr\u003EПериод грудного вскармливания."},{"name":"Состав","value":"Активные вещества: леводопа 250 мг, карбидопа 25 мг; вспомогательные вещества: повидон К-30 9 мг, тальк 6 мг, магния стеарат 5,5 мг, крахмал (сухой) 12 мг, кремния диоксид коллоидный 5 мг, целлюлоза микрокристалллическая 85,5 мг."},{"name":"Действующее вещество","value":"Леводопа+Карбидопа","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:36089532"]}}},{"name":"Способ применения и дозы","value":"Внутрь, с небольшим количеством пищи или после еды, запивая водой и не разжевывая. Поскольку существует конкуренция между ароматическими аминокислотами и леводопой при всасывании, во время применения препарата следует избегать потребления большого количества белков.\u003Cbr\u003EСредняя суточная доза карбидопы, необходимая для подавления периферического превращения леводопы, составляет 70-100 мг. Превышение 200 мг карбидопы не влечет за собой дальнейшего усиления терапевтического эффекта. Суточная доза леводопы не должна превышать 2000 мг.\u003Cbr\u003EНачальная доза - по 1/2 таблетки 2 раза в день, при необходимости можно увеличивать на Уг таблетки в день. Как правило, в начале заместительной терапии дневная доза не должна превышать 3-х таблеток в день (по 1-й таблетке 3 раза в день). Применение в этой дозе рекомендуют в начале лечения тяжелых случаев паркинсонизма. Суточная доза препарата в виде исключения может быть увеличена при монотерапии, но не должна превышать 8 таблеток (по 1-й таблетке 8 раз в день). Применение в количестве более чем 6 таблеток в день должно проводиться с большой осторожностью.\u003Cbr\u003EТидомет Форте при замене леводопы\u003Cbr\u003EПием леводопы прекращают за 12 часов до начала лечения препаратом Тидомет Форте, а в случае приема пролонгированных форм левокарбидопы - за 24 часа. Доза препарата Тидомет Форте в этом случае должна составлять не более 20 % от прежней дозы леводопы. Поддерживающая доза составляет 3-6 таблеток в сутки для большинства пациентов."},{"name":"Побочные действия","value":"Наиболее часто - дискинезии, включая непроизвольные движения (в том числе хореиформные, дистонические), а также тошнота.\u003Cbr\u003EРанними признаками, на основании которых может быть принято решение об отмене препарата являются мышечные подергивания и блефароспазм.\u003Cbr\u003EДругие побочные действия:\u003Cbr\u003EСо стороны нервной системы: психотические реакции, включая бред, галлюцинации и параноидальное мышление, злокачественный нейролептический синдром (см. \"Особые указания\"), эпизоды брадикинезии (синдром \"включения-выключения\"), ажитация, парестезии, головокружение, сонливость, нарушение сна, включая кошмарные сновидения, бессонницу; спутанность сознания, головная боль, депрессия (в т.ч. с суицидальными намерениями), деменция, патологические пристрастия, повышение либидо. Сообщалось о развитии судорог, однако причинно-следственная связь с приемом препарата не установлена.\u003Cbr\u003EСо стороны пищеварительной системы: рвота, анорексия, диарея, запор, диспепсия, сухость слизистой оболочки полости рта, изменение вкуса, потемнение слюны, кровотечение из желудочно-кишечного тракта, язва двенадцатиперстной кишки. Со стороны сердечно-сосудистой системы: аритмия и/или ощущение сердцебиения, ортостатические реакции, включая снижение или повышение артериального, давления (АД), обморок; флебит.\u003Cbr\u003EСо стороны системы кроветворения: лейкопения, тромбоцитопения, анемия (в том числе гемолитическая), агранулоцитоз.\u003Cbr\u003EАллергические реакции: ангионевротический отек, крапивница, кожный зуд, геморрагический васкулит (пурпура Шенлейна-Геноха), буллезные высыпания (в том числе реакции сходные с пузырчаткой).\u003Cbr\u003EСо стороны дыхательной системы: одышка, инфекции верхних дыхательных путей. Со стороны кожных покровов: кожная сыпь, повышенная потливость, потемнение пота, алопеция.\u003Cbr\u003EСо стороны мочевыделительной системы: инфекции мочевыводящих путей, частое мочеиспускание, потемнение мочи.\u003Cbr\u003EИзменение лабораторных показателей: снижение гемоглобина и гематокрита, повышение активности аланинаминотрансферазы (AJIT), аспартатаминотрансферазы (ACT), лактатдегидрогеназы, щелочной фосфатазы, гипербилирубинемия, повышение азота мочевины, положительная проба Кумбса, гипергликемия, лейкоцитурия, бактериурия и гематурия.\u003Cbr\u003EПрочие: боль в груди, астения.\u003Cbr\u003EНиже перечислены другие побочные реакции, которые наблюдались при применении только леводопы, а значит, они могут отмечаться при применении препарата Тидомет Форте:\u003Cbr\u003EСо стороны сердечно-сосудистой системы: инфаркт миокарда.\u003Cbr\u003EСо стороны пищеварительной системы: желудочно-кишечная боль, дисфагия, слюнотечение, метеоризм, бруксизм, ощущение жжения языка, изжога, икота.\u003Cbr\u003EСо стороны обмена веществ: отеки, снижение или повышение массы тела.\u003Cbr\u003EСо стороны нервной системы: атаксия, экстрапирамидные расстройства, падения, тревога, нарушение походки, нервозность, снижение остроты мышления, снижение памяти, дезориентация, эйфория, блефароспазм, тризм, усиление тремора, оцепенение, подергивание мышц, активизация латентного синдрома Горнера, периферическая нейропатия.\u003Cbr\u003EСо стороны дыхательной системы: боль в глотке, кашель.\u003Cbr\u003EСо стороны кожных покровов: злокачественная меланома, \"приливы\" крови.\u003Cbr\u003EСо стороны органов чувств: окулогирный криз, диплопия, нарушение зрения, мидриаз. Со стороны мочеполовой системы: задержка мочи, недержание мочи, приапизм.\u003Cbr\u003EПрочие: абдоминальная боль, усталость, слабость, боль в нижних конечностях, одышка, недомогание, охриплость голоса, возбуждение.\u003Cbr\u003EСо стороны лабораторных показателей: лейкопения, гипокалиемия, гиперкреатининемия и гиперурикемия, протеинурия и глюкозурия."},{"name":"Фармакологическое действие","value":"Леводопа представляет собой аминокислоту, образующуюся из L-тирозина. Дофамин образуется непосредственно из леводопы при участии цитоплазматического фермента -декарбоксилазы ароматических L-аминокислот. Конечным результатом влияния дофамина является угнетение нейрональной активности в полосатом теле головного мозга. Леводопа быстро декарбоксилируется в периферических тканях под влиянием зависимой от пиридоксина декарбоксилазы ароматических L-аминокислот, превращаясь в дофамин, который, однако, через гематоэнцефалический барьер не проникает. Карбидопа ингибирует процесс декарбоксилирования леводопы в периферических тканях, при этом не проникает через гематоэнцефалический барьер и не влияет на превращение леводопы в дофамин в центральной нервной системе. Таким образом, комбинация карбидопы и леводопы позволяет увеличивать количество леводопы, поступающее в головной мозг. При совместном приеме внутрь карбидопа удваивает биодоступность леводопы. Введение карбидопы никогда не приводит к полному угнетению декарбоксилазы ароматических L-аминокислот."},{"name":"Фармакологическая группа","value":"противопаркинсоническое средство комбинированное (дофамина предшественник+декарбоксилазы периферической ингибитор)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В сухом, защищенном от света месте, при температуре не выше 30°С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Лечение: промывание желудка, тщательное наблюдение и ЭКГ-контроль для своевременного выявления аритмии; при необходимости - антиаритмическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Влияние препарата на течение беременности у женщин неизвестно. В экспериментальных исследованиях выявлено, что комбинация леводопы и карбидопы вызывает висцеральные и скелетные изменения у животных. Поэтому применение препарата возможно только в случае, когда ожидаемая польза терапии для матери превосходит потенциальный риск для плода.\u003Cbr\u003EНеизвестно, выделяются ли с грудным молоком леводопа и карбидопа. Имеется одно сообщение об экскреции леводопы с грудным молоком у кормящей матери с болезнью Паркинсона. Поэтому из-за возможного серьезного вредного воздействия препарата на ребенка и с учетом важности проведения терапии для матери, при необходимости применения препарата в период лактации следует либо прекратить грудное вскармливание, либо отменить препарат."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При назначении препарата Тидомет Форте рекомендуется воздержаться от вождения автомобиля и управления механизмами, требующими повышенного внимания и скорости психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EПрепарат назначают с осторожностью при эрозивно-язвенных поражениях желудка и/или двенадцатиперстной кишки, эпилептических припадках в анамнезе, инфаркте миокарда с нарушениями ритма сердца в анамнезе, сердечной недостаточности, заболеваниях эндокринной системы (в том числе сахарном диабете), бронхиальной астме, психических нарушениях, а также при тяжелых нарушениях функции печени и почек."},{"name":"Взаимодействие","value":"- одновременное применение с гипотензивными средствами требует специального внимания в связи с опасностью постуральной гипотензии;\u003Cbr\u003E- при одновременном применении леводопы с ингибиторами моноаминооксидазы (МАО) (за исключением ингибиторов МАО-В) возможны нарушения кровообращения (прием ингибиторов МАО должен быть прекращен за 2 нед). Это связано с накоплением под влиянием леводопы дофамина и норэпинефрина, метаболизм которых замедлен ингибиторами МАО, и высокой вероятностью развития ажитации, повышения артериального давления (АД), тахикардии, покраснения лица и головокружения;\u003Cbr\u003E- при совместном применении с трициклическими антидепрессантами может возникнуть артериальная гипертензия и дискинезия, а также уменьшение биодоступности леводопы;\u003Cbr\u003E- при совместном применении с агонистами D2-дофаминовых рецепторов (производные фенотиазина, бутирофенона), а также с изониазидом возможно уменьшение терапевтического эффекта леводопы;\u003Cbr\u003E- может усиливать действие адреномиметиков, в связи с чем рекомендуется снизить их дозу. При одновременном применении леводопы с β-адреномиметиками, средствами для ингаляционной анестезии возможно увеличение риска развития нарушений сердечного ритма;\u003Cbr\u003E- при применении амантадина с леводопой отмечается потенцирующий эффект;\u003Cbr\u003E- метилдопа и леводопа могут потенцировать побочные эффекты друг друга;\u003Cbr\u003E- пиридоксин является кофактором декарбоксилазы ароматических L-аминокислот -фермента, ответственного за периферическое декарбоксилирование леводопы и образование дофамина. При его назначении больным, получающим леводопу (без ингибиторов декарбоксилазы ароматических L-аминокислот), отмечается усиление периферического метаболизма леводопы и меньшее ее количество проникает через гематоэнцефалический барьер. Таким образом, пиридоксин уменьшает терапевтический эффект леводопы, если дополнительно не назначаются ингибиторы периферической декарбоксилазы ароматических L-аминокислот;\u003Cbr\u003E- при дополнительном назначении ингибиторов декарбоксилазы ароматических L-аминокислот суточную дозу леводопы можно уменьшить на 70-80% при сохранении того же клинического результата\u003Cbr\u003E- при совместном применении с диазепамом, фенитоином, клонидином, производными тиоксантена, папаверином, резерпином, м-холиноблокаторами возможно уменьшение противопаркинсонического действия;\u003Cbr\u003E- при одновременном применении с препаратами лития (Li+) повышается риск развития дискинезий и галлюцинаций;\u003Cbr\u003E- соли железа могут снижать биодоступность леводопы и карбидопы; клиническая значимость такого взаимодействия неизвестна;\u003Cbr\u003E- хотя метоклопрамид повышает биодоступность леводопы, ускоряя опорожнение желудка, тем не менее, он может неблагоприятно повлиять на контроль над заболеванием за счет его антагонизма с дофаминовыми рецепторами."},{"name":"Источник","value":"\u003Ca href=\"https://www.vidal.ru\" target=\"_blank\"\u003EСправочник лекарственных препаратов Видаль<\u002Fa\u003E"},{"name":"Регистрационный номер","value":"П N012502/01"},{"name":"Дата государственной регистрации","value":"20.07.2018"},{"name":"Владелец регистрационного удостоверения","value":"Torrent Pharmaceuticals Ltd","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:16002754"]}}},{"name":"Изготовитель","value":"Torrent Pharmaceuticals Ltd"},{"name":"Фасовщик","value":"Torrent Pharmaceuticals Ltd"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Тидомет","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18025869"]}}},{"name":"Срок годности","value":"35 мес."}]}},"fullSpecsGrouped":{"3062382248963951545":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"головной мозг, нервная система"},{"name":"Назначение","value":"болезнь Паркинсона, паркинсонизм"},{"name":"Показания к применению","value":"Лечение болезни Паркинсона и синдрома паркинсонизма."},{"name":"Противопоказания","value":"Противопоказания:\u003Cbr\u003EПовышенная чувствительность к леводопе, карбидопе или любым вспомогательным компонентам препарата.\u003Cbr\u003EОдновременный прием с неселективными ингибиторами МАО. Необходимо прекратить применение данных препаратов не менее, чем за 2 недели до начала применения препарата Тидомет Форте (за исключением селективных ингибиторов МАО-В (например, селегилина гидрохлорида)).\u003Cbr\u003EЗакрытоугольная глаукома.\u003Cbr\u003EПациенты с подозрением на недиагностированные кожные заболевания или меланомой в анамнезе (поскольку леводопа может стимулировать развитие злокачественной меланомы).\u003Cbr\u003EТяжелый психоз.\u003Cbr\u003EВозраст до 18 лет (безопасности применения у детей не установлена).\u003Cbr\u003EПериод грудного вскармливания."},{"name":"Состав","value":"Активные вещества: леводопа 250 мг, карбидопа 25 мг; вспомогательные вещества: повидон К-30 9 мг, тальк 6 мг, магния стеарат 5,5 мг, крахмал (сухой) 12 мг, кремния диоксид коллоидный 5 мг, целлюлоза микрокристалллическая 85,5 мг."},{"name":"Действующее вещество","value":"Леводопа+Карбидопа"},{"name":"Способ применения и дозы","value":"Внутрь, с небольшим количеством пищи или после еды, запивая водой и не разжевывая. Поскольку существует конкуренция между ароматическими аминокислотами и леводопой при всасывании, во время применения препарата следует избегать потребления большого количества белков.\u003Cbr\u003EСредняя суточная доза карбидопы, необходимая для подавления периферического превращения леводопы, составляет 70-100 мг. Превышение 200 мг карбидопы не влечет за собой дальнейшего усиления терапевтического эффекта. Суточная доза леводопы не должна превышать 2000 мг.\u003Cbr\u003EНачальная доза - по 1/2 таблетки 2 раза в день, при необходимости можно увеличивать на Уг таблетки в день. Как правило, в начале заместительной терапии дневная доза не должна превышать 3-х таблеток в день (по 1-й таблетке 3 раза в день). Применение в этой дозе рекомендуют в начале лечения тяжелых случаев паркинсонизма. Суточная доза препарата в виде исключения может быть увеличена при монотерапии, но не должна превышать 8 таблеток (по 1-й таблетке 8 раз в день). Применение в количестве более чем 6 таблеток в день должно проводиться с большой осторожностью.\u003Cbr\u003EТидомет Форте при замене леводопы\u003Cbr\u003EПием леводопы прекращают за 12 часов до начала лечения препаратом Тидомет Форте, а в случае приема пролонгированных форм левокарбидопы - за 24 часа. Доза препарата Тидомет Форте в этом случае должна составлять не более 20 % от прежней дозы леводопы. Поддерживающая доза составляет 3-6 таблеток в сутки для большинства пациентов."},{"name":"Побочные действия","value":"Наиболее часто - дискинезии, включая непроизвольные движения (в том числе хореиформные, дистонические), а также тошнота.\u003Cbr\u003EРанними признаками, на основании которых может быть принято решение об отмене препарата являются мышечные подергивания и блефароспазм.\u003Cbr\u003EДругие побочные действия:\u003Cbr\u003EСо стороны нервной системы: психотические реакции, включая бред, галлюцинации и параноидальное мышление, злокачественный нейролептический синдром (см. \"Особые указания\"), эпизоды брадикинезии (синдром \"включения-выключения\"), ажитация, парестезии, головокружение, сонливость, нарушение сна, включая кошмарные сновидения, бессонницу; спутанность сознания, головная боль, депрессия (в т.ч. с суицидальными намерениями), деменция, патологические пристрастия, повышение либидо. Сообщалось о развитии судорог, однако причинно-следственная связь с приемом препарата не установлена.\u003Cbr\u003EСо стороны пищеварительной системы: рвота, анорексия, диарея, запор, диспепсия, сухость слизистой оболочки полости рта, изменение вкуса, потемнение слюны, кровотечение из желудочно-кишечного тракта, язва двенадцатиперстной кишки. Со стороны сердечно-сосудистой системы: аритмия и/или ощущение сердцебиения, ортостатические реакции, включая снижение или повышение артериального, давления (АД), обморок; флебит.\u003Cbr\u003EСо стороны системы кроветворения: лейкопения, тромбоцитопения, анемия (в том числе гемолитическая), агранулоцитоз.\u003Cbr\u003EАллергические реакции: ангионевротический отек, крапивница, кожный зуд, геморрагический васкулит (пурпура Шенлейна-Геноха), буллезные высыпания (в том числе реакции сходные с пузырчаткой).\u003Cbr\u003EСо стороны дыхательной системы: одышка, инфекции верхних дыхательных путей. Со стороны кожных покровов: кожная сыпь, повышенная потливость, потемнение пота, алопеция.\u003Cbr\u003EСо стороны мочевыделительной системы: инфекции мочевыводящих путей, частое мочеиспускание, потемнение мочи.\u003Cbr\u003EИзменение лабораторных показателей: снижение гемоглобина и гематокрита, повышение активности аланинаминотрансферазы (AJIT), аспартатаминотрансферазы (ACT), лактатдегидрогеназы, щелочной фосфатазы, гипербилирубинемия, повышение азота мочевины, положительная проба Кумбса, гипергликемия, лейкоцитурия, бактериурия и гематурия.\u003Cbr\u003EПрочие: боль в груди, астения.\u003Cbr\u003EНиже перечислены другие побочные реакции, которые наблюдались при применении только леводопы, а значит, они могут отмечаться при применении препарата Тидомет Форте:\u003Cbr\u003EСо стороны сердечно-сосудистой системы: инфаркт миокарда.\u003Cbr\u003EСо стороны пищеварительной системы: желудочно-кишечная боль, дисфагия, слюнотечение, метеоризм, бруксизм, ощущение жжения языка, изжога, икота.\u003Cbr\u003EСо стороны обмена веществ: отеки, снижение или повышение массы тела.\u003Cbr\u003EСо стороны нервной системы: атаксия, экстрапирамидные расстройства, падения, тревога, нарушение походки, нервозность, снижение остроты мышления, снижение памяти, дезориентация, эйфория, блефароспазм, тризм, усиление тремора, оцепенение, подергивание мышц, активизация латентного синдрома Горнера, периферическая нейропатия.\u003Cbr\u003EСо стороны дыхательной системы: боль в глотке, кашель.\u003Cbr\u003EСо стороны кожных покровов: злокачественная меланома, \"приливы\" крови.\u003Cbr\u003EСо стороны органов чувств: окулогирный криз, диплопия, нарушение зрения, мидриаз. Со стороны мочеполовой системы: задержка мочи, недержание мочи, приапизм.\u003Cbr\u003EПрочие: абдоминальная боль, усталость, слабость, боль в нижних конечностях, одышка, недомогание, охриплость голоса, возбуждение.\u003Cbr\u003EСо стороны лабораторных показателей: лейкопения, гипокалиемия, гиперкреатининемия и гиперурикемия, протеинурия и глюкозурия."},{"name":"Фармакологическое действие","value":"Леводопа представляет собой аминокислоту, образующуюся из L-тирозина. Дофамин образуется непосредственно из леводопы при участии цитоплазматического фермента -декарбоксилазы ароматических L-аминокислот. Конечным результатом влияния дофамина является угнетение нейрональной активности в полосатом теле головного мозга. Леводопа быстро декарбоксилируется в периферических тканях под влиянием зависимой от пиридоксина декарбоксилазы ароматических L-аминокислот, превращаясь в дофамин, который, однако, через гематоэнцефалический барьер не проникает. Карбидопа ингибирует процесс декарбоксилирования леводопы в периферических тканях, при этом не проникает через гематоэнцефалический барьер и не влияет на превращение леводопы в дофамин в центральной нервной системе. Таким образом, комбинация карбидопы и леводопы позволяет увеличивать количество леводопы, поступающее в головной мозг. При совместном приеме внутрь карбидопа удваивает биодоступность леводопы. Введение карбидопы никогда не приводит к полному угнетению декарбоксилазы ароматических L-аминокислот."},{"name":"Фармакологическая группа","value":"противопаркинсоническое средство комбинированное (дофамина предшественник+декарбоксилазы периферической ингибитор)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В сухом, защищенном от света месте, при температуре не выше 30°С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Лечение: промывание желудка, тщательное наблюдение и ЭКГ-контроль для своевременного выявления аритмии; при необходимости - антиаритмическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Влияние препарата на течение беременности у женщин неизвестно. В экспериментальных исследованиях выявлено, что комбинация леводопы и карбидопы вызывает висцеральные и скелетные изменения у животных. Поэтому применение препарата возможно только в случае, когда ожидаемая польза терапии для матери превосходит потенциальный риск для плода.\u003Cbr\u003EНеизвестно, выделяются ли с грудным молоком леводопа и карбидопа. Имеется одно сообщение об экскреции леводопы с грудным молоком у кормящей матери с болезнью Паркинсона. Поэтому из-за возможного серьезного вредного воздействия препарата на ребенка и с учетом важности проведения терапии для матери, при необходимости применения препарата в период лактации следует либо прекратить грудное вскармливание, либо отменить препарат."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При назначении препарата Тидомет Форте рекомендуется воздержаться от вождения автомобиля и управления механизмами, требующими повышенного внимания и скорости психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EПрепарат назначают с осторожностью при эрозивно-язвенных поражениях желудка и/или двенадцатиперстной кишки, эпилептических припадках в анамнезе, инфаркте миокарда с нарушениями ритма сердца в анамнезе, сердечной недостаточности, заболеваниях эндокринной системы (в том числе сахарном диабете), бронхиальной астме, психических нарушениях, а также при тяжелых нарушениях функции печени и почек."},{"name":"Взаимодействие","value":"- одновременное применение с гипотензивными средствами требует специального внимания в связи с опасностью постуральной гипотензии;\u003Cbr\u003E- при одновременном применении леводопы с ингибиторами моноаминооксидазы (МАО) (за исключением ингибиторов МАО-В) возможны нарушения кровообращения (прием ингибиторов МАО должен быть прекращен за 2 нед). Это связано с накоплением под влиянием леводопы дофамина и норэпинефрина, метаболизм которых замедлен ингибиторами МАО, и высокой вероятностью развития ажитации, повышения артериального давления (АД), тахикардии, покраснения лица и головокружения;\u003Cbr\u003E- при совместном применении с трициклическими антидепрессантами может возникнуть артериальная гипертензия и дискинезия, а также уменьшение биодоступности леводопы;\u003Cbr\u003E- при совместном применении с агонистами D2-дофаминовых рецепторов (производные фенотиазина, бутирофенона), а также с изониазидом возможно уменьшение терапевтического эффекта леводопы;\u003Cbr\u003E- может усиливать действие адреномиметиков, в связи с чем рекомендуется снизить их дозу. При одновременном применении леводопы с β-адреномиметиками, средствами для ингаляционной анестезии возможно увеличение риска развития нарушений сердечного ритма;\u003Cbr\u003E- при применении амантадина с леводопой отмечается потенцирующий эффект;\u003Cbr\u003E- метилдопа и леводопа могут потенцировать побочные эффекты друг друга;\u003Cbr\u003E- пиридоксин является кофактором декарбоксилазы ароматических L-аминокислот -фермента, ответственного за периферическое декарбоксилирование леводопы и образование дофамина. При его назначении больным, получающим леводопу (без ингибиторов декарбоксилазы ароматических L-аминокислот), отмечается усиление периферического метаболизма леводопы и меньшее ее количество проникает через гематоэнцефалический барьер. Таким образом, пиридоксин уменьшает терапевтический эффект леводопы, если дополнительно не назначаются ингибиторы периферической декарбоксилазы ароматических L-аминокислот;\u003Cbr\u003E- при дополнительном назначении ингибиторов декарбоксилазы ароматических L-аминокислот суточную дозу леводопы можно уменьшить на 70-80% при сохранении того же клинического результата\u003Cbr\u003E- при совместном применении с диазепамом, фенитоином, клонидином, производными тиоксантена, папаверином, резерпином, м-холиноблокаторами возможно уменьшение противопаркинсонического действия;\u003Cbr\u003E- при одновременном применении с препаратами лития (Li+) повышается риск развития дискинезий и галлюцинаций;\u003Cbr\u003E- соли железа могут снижать биодоступность леводопы и карбидопы; клиническая значимость такого взаимодействия неизвестна;\u003Cbr\u003E- хотя метоклопрамид повышает биодоступность леводопы, ускоряя опорожнение желудка, тем не менее, он может неблагоприятно повлиять на контроль над заболеванием за счет его антагонизма с дофаминовыми рецепторами."},{"name":"Источник","value":"\u003Ca href=\"https://www.vidal.ru\" target=\"_blank\"\u003EСправочник лекарственных препаратов Видаль<\u002Fa\u003E"},{"name":"Регистрационный номер","value":"П N012502/01"},{"name":"Дата государственной регистрации","value":"20.07.2018"},{"name":"Владелец регистрационного удостоверения","value":"Torrent Pharmaceuticals Ltd"},{"name":"Изготовитель","value":"Torrent Pharmaceuticals Ltd"},{"name":"Фасовщик","value":"Torrent Pharmaceuticals Ltd"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Тидомет"},{"name":"Срок годности","value":"35 мес."}]}],"transitionId":"tr_2698323156147191771"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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696 ₽

  • Сегодня, самовывоз • 0 ₽
ЕАПТЕКА
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  • Мирапекс ПД таб. пролонг. действ., 0,375 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k1momc2qbic/toggleWishlist":{"skuId":"186879996","productId":1404748470,"offerId":"JkJuLXXJVUglfTCGJEa-fw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUItoXrnQUQ/J+OWRjGtN4HIO3ZwQc=","sign":"/xEAAK9YJncVeIC5NgMHGpoUgCzMCqxSdjAYaCdxVp0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k1momc2qbic/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мирапекс ПД таб. пролонг. действ., 0,375 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    Цена 150 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k1momc2qbic/addToCartButton":{"offerId":"JkJuLXXJVUglfTCGJEa-fw","skuId":"186879996","pendingCartItem":{"productId":1404748470,"offerId":"JkJuLXXJVUglfTCGJEa-fw","showPlaceId":"OTNDnItfwRMjN9MRHuEMMvbf7EzBCuh-VlBhaeLjQUy8QxJ5ofvoC7ndTxoHHer2RmLF9HqLaF3gtJEgYbueoVP44TsGgBDXUYJpi-WRjEk4bDR6AOMq0KcBU4A4C2SlaVWUmejKVi3zGbP_mPK6qaUAtGU3AAttUPFNKCLXRHceFxUTDmpF9tHE6dDxqSHgIY2A7ppFeJ0IiXCP1v25Hg,,","feeShow":"OTNDnItfwRMjN9MRHuEMMvbf7EzBCuh-VlBhaeLjQUy8QxJ5ofvoC7ndTxoHHer2RmLF9HqLaF3gtJEgYbueoVP44TsGgBDXUYJpi-WRjEk4bDR6AOMq0KcBU4A4C2SlaVWUmejKVi3zGbP_mPK6qaUAtGU3AAttUPFNKCLXRHceFxUTDmpF9tHE6dDxqSHgIY2A7ppFeJ0IiXCP1v25Hg,,","skuId":"186879996","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"150","currency":"RUR"},"hid":"15756525","name":"Мирапекс ПД таб. пролонг. действ., 0,375 мг, 10 шт.","label":"9ldfcfn2rjh","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4393885,"key":"img_id573416770212722853.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96UWkyu_L0koKe1nu6_kmXB_fuvMS8samWLDxc0AC_fLNAg64Km3zRtoKmXvEuNe8wpYvESfFnkcHgx1IUns7mDrSw5ukoP4_RXKrZpGknOyXTxo9_tEqfx-iWfosDS1kzV_NRQM1p5LnsEyxZnFA-W6Kwx1J7qFcbSaYESTsRX77lkJR_coMba-pPNKzPyrUMoLMn1gJiVBroOft3Km4cY4gkK63jasfzXErgbZYe-bW60dPkX_C5evipmnPwZg7sf6m55O7U87RmP8MgCruY6mfSnn0LsH5W2pJmh7KnxrG4hy0yNeiAa-H1DLeY4EQVCwMDIaYGt2469YhjHvDzGvtPjafmmsBPrwcRdGa8fTCUTtuZt2zWk22Xkws1HtBi2F9EL4qouU4jYjC6P1DSaRvPhFUCKRmjo-CZ6WDZpvzC2XZ_fdf_xuqQA_DEOJTrvkGjs5pQP6mGxUVvsVw-8IfEoEZkaTySkFZ8inYVdU6l742v6hlQDEOG7uOr88bNW0Sl38T8Y6-27SSy6J7_NTkrGIF3FxBfQyL2Zv-ZiGdtmixNIz00IzzBQj8u_zdQh7yH-Bt_HhfQdi0ojWAor73N6Gchu5LeSrNrbbtQwleX8fjUfDKXhXQvgkCKyFe0GyJQcjUd_XNRJHWZp9rZPW-lgNh5U44dyfct2wV7jMmQXYWtQC0KcCLawe1FYvNjeirnhpNx65xrOxJzJfx0PIJA84W1gMGzvfCd_oBq1O_5fxumQing3ON5IxA97ixhHiKrN-3hFpBAG2PRxdxU0iCWEOawefRLaqk13Flz0CVs7cFu3rbYWQVXmlM7JCWRpoTVMCpQoGo8J94vRpxqCUEOR6CzuXzCxlX-AATlapP1lcx92CDJolkIkxskD-T3nLt5wKT_JsIke7nNtSXfl_Fg4WpDjzkioBTtH0GEXkwC46WyxHRraR4i0-cBHAX9QLhHp9K5jvKLlLsWNxs_fsepFqrIV_zi02yVQUTFCmTxmzEwLEJ4diZgTrQijEFgXC2kyYXmCC_VtnGKZ3tVX3d7it8gZ5fSqNJmu2nLsYbeTbNeFxrK_7Iy_DlpUTHjmCGCOomFcxXszymFNVQwhlk5r9icFE_GUn8SiYcg0NBJCJp-uDTRUhfYyVAehfHeYgibEycSiOj9Hk7SCudlOHCf6xfVj4fxKAAlJBIQR_9KMuJ1CvWz2DG1RNdDPxLbVRWU6ABXS7KpTCGzsMge_7UU9nbph_doTWKei9-8XVfdDaYQZRHPttykjwZ8pj2_GemQ7sXL7biPLNrZvBEv5AH3r1MsuYeZTBmlKjHijOj45xEe3iPnk8F3hTKrJuetEqImm8GCgEfeUofVOjMAi8P6OOV18B50arGPI7OZdewk7f9TnGoL2nViWi1RGxwe5X88frBVXR_BfRXj2LHZ8MlyiDQeR3BLWKaTAO51ncWi7qcJF_JZizEQUUojbMQXYSIhbuP5BuRowu_j2aTLXi1BXSfnffpDOAuP0u5rXAD4hcH8j36fymjsudyPQ1OXhctFUxq4-Stzr3OX3m9_QWwl2wkIEHgOJyUTq3C9FOsvZNPjxTR7TqUqi33LbOkOVwVvoq-oMRIBJV8tfe0BvCREgHs5loidJrxUToZae1CVkIhsDIKJvEXyMMHKAsB9TOcOr9YJpYTeTcqmkAWMEnl06pJFazpnblBtG-aIOetOY9wqzSyq2oDyrkyRQBtjYRf_0Q75FcmX_0yY5yKMtBXuypQpptBXZdN8BtMOQYTUIdVGwQir9VJxRGV80qA0GonQJ2XcKw4eaNBJpDPW53TgNyN7oX3pgbWtT5zf93q6DFCNxZFn8VKjrb99mGZPjBmpxEtRrBpt2yEW7TE-IgNEAXer3XCUQKm0GuejzVZLNH7wlvip_udrwly8gwHU4-otU-OhXV0vXjC9JHcOjmxqlmOyBkmL_cmn5KhQpwvBOVhqN6OFs9tnA3Pea4YSTvMI-C4igx4rktaL6oeGRha_Ks_3uHr8Q9pnpjzra3P_u52DBUGIfpJXdOhYy2gXhSnCrazKNdEkZtsoQPzdqwzy6DP-WpcsngkskOVVu1MOYk91au3CZan4m3fR0S5jk-wFYMmeSfehVl3gGVHAjW1Y_ouzicNsJBY4Ro2OswoF-NmK1eLcKunhiIsrcsT2RQewAVxhRKLekqJRlh568EmBoKvy-8yl2kqzK-r-PbfyLTzvJB4Oe8SwEAgsJSobVKUT1ZaVL2l07dFxJYhBrIZyNt3XdXpuR4dgpMhSi8_ozMmHMgKqK7ZsbKT1Xkq7EQlYd0uVjYVixz7Fet1KK6tT_vApxrBUEAKI414iBfonvIYs0oGBvganYwOEvKqr76hlN9jNaJjiXQujnuiB-RsziMbTASmFmzDd3lf2VHKk6PgBbuzuQMCuf42o-R28d5jyCvnHB9BB3TZXfxELORhNq8XtA-jh4rTv5Ad6Gi11ux75cP1KZBQZQMYb9sVgt6Lc0wCVatlGTgerNhVv0EI1te9rRPVIPsVpxIg2GkbZ6bjQezdJZHddEMSP3eCJUXpdib2e5YNzNYn62GY6tBTfXhfWH56bAa4UqzuLYNZJtzlDUk5rN05CWgsVBvFKqj31edzFgEisOQSMgrrz4ql309-MUUtzrD4nwBb2PO6yklcJbgoqJTtV560blMF3DITp1yH7w5U9pnuMFA4biT-0k9s6BqLXJH_7x3iOOz2G46suQUDwaHnzCpeM744waPcKuCgw-fsS0hITyhOMzsaBUZ3meqXJGzjToaBXfUQBoMl-zVfCSLNgnSoqjf2UEKJuecDiE_qVdT2C3Q7SLdPAKH75EPZmhDz3dFjrRsqY1kpeUp8hwQK97-46lQtGV8J5JTkbFGEIyGQcf4M4gRtvxJKUaxibZ7qO01rMvYfhqFsSgVEjxVkmO-o2znmQnLGpBfRpOEGzSPJANAonhDkYrEg66NGS74c4TnnqwYazyKHXccpCS2XIFqtlm9XsT_fe2RMBZRoHxJKVER7YGUSObP5zgl-F5ILOkuvtfNeG117z0j5K-ypIro4rVtrlZf6Ai8-pj-juyC-a6zUJtXChogXrqH9PSFcc9L3l6cdXCNyDpnPztB6viMak-nXFsvCu95tGBWpZ6z9ckUwEfgPOoFNQ_s3YWvJ-yImU_W6nVjV8sENJ4URGP4jccuA57yMT-M6xa7IfbX6cn2kBp3xRmTjH2CxMAoCgDe2j7eIkEnw-zff98cIXnieIOo-duKLqPqFVaG_S_wnG5X_shOM-vfmEkZ2bqEFYdoPCHApLuQMNZTEwLR2TX2n0flVVfoFBsnVzvKMpgMSXVDSriH/b64e=1/sign=eada0d969eac699bf02637b8165f508e/keyno=MARKET_1/*","showUid":"17179979722807724917106002","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUItoXrnQUQ/J+OWRjGtN4HIO3ZwQc=","sign":"/xEAAK9YJncVeIC5NgMHGpoUgCzMCqxSdjAYaCdxVp0="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUItoXrnQUQ/J+OWRjGtN4HIO3ZwQc=","sign":"/xEAAK9YJncVeIC5NgMHGpoUgCzMCqxSdjAYaCdxVp0="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k1momc2qbic/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Наком таб., 250 мг+25 мг, 100 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-jf8sp2xv7oj/toggleWishlist":{"skuId":"101978096925","productId":1827571268,"offerId":"UU1LYZz9YybVgsLw0wEpdg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIxIy65wYQnYr58vsCGMSc0Acg7dnBBw==","sign":"0Vm/num+V7hLH8w/1soSW2mxofIXUvNhA+UA0UIgqVc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-jf8sp2xv7oj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Наком таб., 250 мг+25 мг, 100 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 1 422 ₽
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  • Армадин лонг таб. с пролонг. высвоб. п/о плен., 375 мг, 30 шт.
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    Армадин лонг таб. с пролонг. высвоб. п/о плен., 375 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 53 оценки
    Цена 718 ₽
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  • Леводопа/Карбидопа/Энтакапон-Тева таб. п/о, 100 мг+25 мг+200 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ylsvg26b2j/toggleWishlist":{"skuId":"101882882956","productId":1792576698,"offerId":"1H-_lGN1pdgycpDDr-Cnxw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIupni1gYQjNfFxfsCGNb9jQcg7dnBBw==","sign":"lpAFWney9qzkpEpbpJLcrBkYBNEG0nhSJto5JasIVzA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ylsvg26b2j/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Леводопа/Карбидопа/Энтакапон-Тева таб. п/о, 100 мг+25 мг+200 мг, 30 шт.

    Рейтинг товара: 4.3 из 5
    на основе 15 оценок
    Цена 3 639 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ylsvg26b2j/addToCartButton":{"offerId":"1H-_lGN1pdgycpDDr-Cnxw","skuId":"101882882956","pendingCartItem":{"productId":1792576698,"offerId":"1H-_lGN1pdgycpDDr-Cnxw","showPlaceId":"OTNDnItfwRMjN9MRHuEMMvbf7EzBCuh-vKCMVHZcAnEB0AU1oSnnnf3VyhHOcZRXjgbMrtwYxOZqpZVy3uO9gwGRfQYBcKpwvclzIJ7RMu8qu_cgKLpgUhErb-PYQ5c0iHzgkRoSLb9sHHjrRDL2BfBSeqXqnPBH3ZrWnEJRR543Sst1sasCu7xjpF6v2mz5Z01sR0ojT1a06k-X289jAw,,","feeShow":"OTNDnItfwRMjN9MRHuEMMvbf7EzBCuh-vKCMVHZcAnEB0AU1oSnnnf3VyhHOcZRXjgbMrtwYxOZqpZVy3uO9gwGRfQYBcKpwvclzIJ7RMu8qu_cgKLpgUhErb-PYQ5c0iHzgkRoSLb9sHHjrRDL2BfBSeqXqnPBH3ZrWnEJRR543Sst1sasCu7xjpF6v2mz5Z01sR0ojT1a06k-X289jAw,,","skuId":"101882882956","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"3639","currency":"RUR"},"hid":"15756525","name":"Леводопа/Карбидопа/Энтакапон-Тева таб. п/о, 100 мг+25 мг+200 мг, 30 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  • Прамипексол таб., 0.25 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-c0h0pkqoju/toggleWishlist":{"skuId":"101703977118","productId":1698374632,"offerId":"Q_BVt2Bfxu27PakdNMR2fA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI6MfsqQYQnpGe8PoCGISpsggg7dnBBw==","sign":"DNcF6Kvn1SRR4Nu9SMloDHSi/XyjU0cX9EMeSV/SHf8="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-c0h0pkqoju/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Прамипексол таб., 0.25 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 23 оценки
    Цена 246 ₽
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  • Ламитор таб., 25 мг, 30 шт.
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    Ламитор таб., 25 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 263 ₽
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  • Бривиак таб. п/о плен., 25 мг, 56 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-55gf260gaz8/toggleWishlist":{"skuId":"228018734","productId":1404748495,"offerId":"GQQ6gh7b9eRZqzsDIDWZrQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIz4XrnQUQrpTdbBig2q4IIO3ZwQc=","sign":"aW/5Pwlwd4ZMIXgUmpl+CQORpZJF4TX92Ym0Ag2v/4A="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-55gf260gaz8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Бривиак таб. п/о плен., 25 мг, 56 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 5 698 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-55gf260gaz8/addToCartButton":{"offerId":"GQQ6gh7b9eRZqzsDIDWZrQ","skuId":"228018734","pendingCartItem":{"productId":1404748495,"offerId":"GQQ6gh7b9eRZqzsDIDWZrQ","showPlaceId":"OTNDnItfwRMjN9MRHuEMMvbf7EzBCuh-QgC8JU5oMicPWnl_aAp9_qhmAguWgWpWOPu8swUaInpCAOPU0ZB0HLZV81ENfdxC6g5B8lSuvcT9M0U3flvIbG-oBIu8Jw-ROVR1ZZTZINnGBr9M8_dNrSpvLaeQncQyFga2INWJtuikFbO-EswVArVh6sXW6ySsxW2ESPL7s2IN9kxo3sH0Nw,,","feeShow":"OTNDnItfwRMjN9MRHuEMMvbf7EzBCuh-QgC8JU5oMicPWnl_aAp9_qhmAguWgWpWOPu8swUaInpCAOPU0ZB0HLZV81ENfdxC6g5B8lSuvcT9M0U3flvIbG-oBIu8Jw-ROVR1ZZTZINnGBr9M8_dNrSpvLaeQncQyFga2INWJtuikFbO-EswVArVh6sXW6ySsxW2ESPL7s2IN9kxo3sH0Nw,,","skuId":"228018734","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"5698","currency":"RUR"},"hid":"15756525","name":"Бривиак таб. п/о плен., 25 мг, 56 шт.","label":"ldr3wbeoit","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":1349652,"key":"img_id6269163059981352320.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96WFVmZtSFtMyb3yJJ0vvI_f_VoLwr8_fQDSzGtzWieo5zD8FURYjK2rGyXidTB0phTeRM53sqDraooMwE-pHDeSt-5W76KtUnJCOnwtplb0PicnK6RGr4IoYq5zCPlEzuAgHIQghWRz-YHaMtsiiQbMvM-880Ad4mUdnRkyvcFYgaHGPDQzJxNiW6yzkQjHWAHrHV8tDxQQyaPOQcOukJZUhX6q9jyicJI7TTCKI_H6rW3f1mmwogHRc69cYzA6j_Ggutyd5WAEhJRJm6XTbgOcdSZ_tViSvnColf1UWLVU9V1MjQnedi_790QCsPM2g79hVmWBjEJueFlMynwCTvV2nJfzLOQE65zDyb747gskptlP3cqLNeJX5V18FGcNQE6uJlI6CegBwH7Y12zUqOQ6NJ1eP79NEx7fsPdVW-EOdjjo4qH8F0J2hra7sIUs8ErfBXhhFp3MuuTXOgrgA1F0BKZbmOzEJl7fNqL3p5Tq8LlTKOf3IdyvKHgOnzTeRssFdAUq72sD_YXDWRx8mTOZbpxOcmOA2JtNxH5L3CPcsiUXgQ6bXZ5Y5UI1-N7ODndteoj3pmj2wbF0DzWncqLw2XN9aHB_vyenhhgQxg2rnAApdQA-1zN94zbs2XANg2h6L0_Z-OVh12l5WKoUb6M9Sz6PjVMrwX0jw9pU6V51lyKtjmhvjyWVXod9kQMcMyG3beTU5MBvveMyHp6ZhIYEjlshiDrodXThBWijOb_mhZRXdM6JgE9wNHXeTKfkhKuGaCWfEEQwmiYZ2Ml525AKH92zySK6uqnbICvW65_u4e4kHQTb1JnMrP2xMBSwdej_xZ1q7iaWZU2aU_pnWNmOQApJNCDgN7X_e-R8miY_1Gc5YK9aI80C0KsSnc8HRxJXOV9GBZ_VV_1YHYEG7jT83ol92m6YJ_vKz1uxTxg4vn5tFGctcOvccyrirJPaYxESUFDdEHW3ia_QGGPIo6KRb0osokT6cg4764h7pnVR1mbyX0I4XhDojOHGKUa4zrXouN1Bq0flVCgVxlRSHLFy0lnLXT0HqESf8-Tc1OmnyA5uFQppq1VGRjcCr648Y-k-XzDypNVQz70U-9yP6HVyZJj_RWQi79hCAnntsIgYxdRQVNfgU5w1aHlmiLmuAiazNUyY2JT5oEN8ltGJWAlK7f34Wv-oeEW_HFhj3vr_0hLUjM-IWGPNuL9ViZ0V8pl5JO-qBeRzKRYpMVJ8hRSY-5FhFf6hZVTLUQHuAEJSrGNn_b7JdqWPJQhidNN_61fr32tTtVYR_x1sA4cFoOI-gtWr5sArnThYRKIRUEQ3EkulRtTJdoeY9eca9Dld7OIbqgx5PtWNNG0g_Vyoy5XZi8doKPBuNG2WzMFaXYid_gucsHcDjVMxEKCbfG78Pb101pG2W2aNHj8ifwSq8HXbDppxx1MNEuPrZlX6GYZST_es8F3tGHYd06QBc93y9_ZYdg7h1C1qWvBCNwcHwTUOGDkE4lTfxPat4lRHoT6pqy6JzCWXObWpmHO9VaYBLmw7FCpgw9jgBfXwWA1KmUjwpU9WRt6NpuwURsE1YMjm28jfCplVq3o2FEyOp1HIbm7Loosd4f5SoHBy23BNnhpZPDJXukbc-YlhI5U-y0Cy7blPWSx6XIVIB2z282YVW4Wt8NjZgdWfs-kpVX0LOaBsMErEIP7rJYJiSzvPi24SNHa1E3d-BQqvzV1ltdKusqf_REq6ycoH7zhL4PL2iPCV0FmEV1c52qgMxtQodbu7OH0MFcezFtKzd-ypZ7syauFuj2MSnZB1EgViouIWLBw5UtngAE0TEfIGzxu8B3QPXunfPH7rubO6YMVaTctV9cvH1yglohpnxBnKprNu4yBZEjbnOJ8EZWZB01IFga7FzzkE_cDx37pLd2eRVT0V4Y7gHiRh68YUtG6y4zFRXg8EqcLWKxNCH-FqW5hKpd346SZIf7oj9fGmW1EO2xBD05Rvk6DkrEu_GLpZkrL4TDqi3HRB6yjIUQI28sinGnEgSopwJPi8vUXWP4iSVRhdA6zXlcbJ0xNkBp9bg0E1XqeuiUxnTsRwwPSwSr-_Q-7cB3wGEvI7AcwjsMCf_DqsvtIzUaE3ZqsmFlekF75_FuNZopc6poEaJzELA1wbCMOKJKYJhH_mUWRjwsD0rh40XotERiphpXAlGlL4z4OL4nY3OVqSk-zwaegsx5gyOVVG-ilS3JFDEczOXdFaGMvycL2wjTnAfF_tBq5WyG-oy7yUbQ6U64IU5485-LsnMDlJMLKlNirhwFB6eD-Y_fsodLFy7bfHfCGsCnSvMxYvjj9sUX8qRrLk7ozCdYLcxBx8GNbZH64BGd-buK3_6JEKixVMyuKPDiQRjGA0j42BtKtGcbidG8eBNe4B7bCCxzbbgZ0fOYtvAvgtcge7kcSCW_FRA3_Y0f03vqbwjVdAqXeXa0kHTz-FFDxWFIdXjvr9_8oy5riuz980-VO8O5W7BeBwpbHITEYKg4HBTnP57EU-rsiufaWfjrEB5frpRoAHb0JqzTqJoTz6S_rHJ9z63jgq3EZaBJukkfNpY5ttzx8XICMNMPRO4usxOVjMuQqCf5BRF8jgQz5vGm0V4DE4e0NwHZ_ZpMD_RYDaIne8JXLkZZ2Zqkn4zsuKx2aDyK0otvT0e6EaMFkmvR_T3glVD1uQxMcYQctLDnWqciEnS5w8lpv7vQtoZldB5zrOqPVGMWnJGQR0I90z0QBFCCmvE2cNK5OYnz6xwBSKEKKqgOGgnyu2j5Qb-TmAajxEmk3KdPJFh7yG615wzBlF_S5BaHGEi0nka4CqIcGKaO_zcdPUL-Z2Hw36XWnvitE8LLItGPRzQl-T_JklXXZ-HRRXCbXlOpxbA2lTpKBU3DU7CsMsZRjobrWbFK48uHQYEHFd9WRMCL7PuovV5E4Jq6p-fGo2xNTMmiR3y7ZwONM-d244NMqy9xd8jyKT6BhhnrMxhLB_WVT2tin6_XdqaLTnUDcj3byyjxladjtGliiqKHxW6pUGq9IrSJMzWeCGdQpQMWLcD4kiARNQcwFGkfY6TvYyuCXhJm5NBzx8mckktThamaZGa0aqa-NHOOZm1-3rOULN0t-VnV5FH1EtdiuGe2-BPr03CEF_68XeSIkwztTWYQJaslfn3XcCs0tD0wgX_xNTVlxnX_CrQz_wYkBDuWfX4TaEDgY-j4_se-u-FIjeXUBtndpoMOju_wueRRC7WP4LtNe-f5yL5fTEfW3hllEQUAwd8npHd1-n1dYiW4FWMMexRZbMuZRM0itNWWHOn07gls5p7AES-u41DgDWhD4,/b64e=1/sign=5508856b794ec703da793b44d0c4c921/keyno=MARKET_1/*","showUid":"17179979722817746214306008","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIz4XrnQUQrpTdbBig2q4IIO3ZwQc=","sign":"aW/5Pwlwd4ZMIXgUmpl+CQORpZJF4TX92Ym0Ag2v/4A="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIz4XrnQUQrpTdbBig2q4IIO3ZwQc=","sign":"aW/5Pwlwd4ZMIXgUmpl+CQORpZJF4TX92Ym0Ag2v/4A="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-55gf260gaz8/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Проноран таб. с контрол. высвоб. п/о, 50 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-x2n9vkioqz/toggleWishlist":{"skuId":"101618541704","productId":1697874464,"offerId":"Jp91ohtXBAod-LfpceAoaw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIoITOqQYQiMm/x/oCGKXe0Acg7dnBBw==","sign":"nbzeYLDRomfbip4LVx1pYWi6Ka6DAww8oWtGrxJILfM="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-x2n9vkioqz/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Проноран таб. с контрол. высвоб. п/о, 50 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 439 ₽
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  • Метостабил таб. п/о плен., 125 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-alur2k3j4oj/toggleWishlist":{"skuId":"101813288735","productId":835941480,"offerId":"FyoblG8eP9yWwa18DvEI8A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07LZs8PjxstwEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI6OjNjgMQn/6tpPsCGISpsggg7dnBBw==","sign":"OsIwfCQx99E1eHV5CqcFVrYdElZVxa+Q+jl1e2BCGDQ="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-alur2k3j4oj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Метостабил таб. п/о плен., 125 мг, 30 шт.

    Рейтинг товара: 4 из 5
    на основе 5 оценок
    Цена 215 ₽
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  • Сердолект таб. п/о, 4 мг, 30 шт.
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    Сердолект таб. п/о, 4 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 1 651 ₽
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Инструкция

Показания к применению

Лечение болезни Паркинсона и синдрома паркинсонизма.

Противопоказания

Противопоказания:
Повышенная чувствительность к леводопе, карбидопе или любым вспомогательным компонентам препарата.
Одновременный прием с неселективными ингибиторами МАО. Необходимо прекратить применение данных препаратов не менее, чем за 2 недели до начала применения препарата Тидомет Форте (за исключением селективных ингибиторов МАО-В (например, селегилина гидрохлорида)).
Закрытоугольная глаукома.
Пациенты с подозрением на недиагностированные кожные заболевания или меланомой в анамнезе (поскольку леводопа может стимулировать развитие злокачественной меланомы).
Тяжелый психоз.
Возраст до 18 лет (безопасности применения у детей не установлена).
Период грудного вскармливания.

Способ применения и дозы

Внутрь, с небольшим количеством пищи или после еды, запивая водой и не разжевывая. Поскольку существует конкуренция между ароматическими аминокислотами и леводопой при всасывании, во время применения препарата следует избегать потребления большого количества белков.
Средняя суточная доза карбидопы, необходимая для подавления периферического превращения леводопы, составляет 70-100 мг. Превышение 200 мг карбидопы не влечет за собой дальнейшего усиления терапевтического эффекта. Суточная доза леводопы не должна превышать 2000 мг.
Начальная доза - по 1/2 таблетки 2 раза в день, при необходимости можно увеличивать на Уг таблетки в день. Как правило, в начале заместительной терапии дневная доза не должна превышать 3-х таблеток в день (по 1-й таблетке 3 раза в день). Применение в этой дозе рекомендуют в начале лечения тяжелых случаев паркинсонизма. Суточная доза препарата в виде исключения может быть увеличена при монотерапии, но не должна превышать 8 таблеток (по 1-й таблетке 8 раз в день). Применение в количестве более чем 6 таблеток в день должно проводиться с большой осторожностью.
Тидомет Форте при замене леводопы
Пием леводопы прекращают за 12 часов до начала лечения препаратом Тидомет Форте, а в случае приема пролонгированных форм левокарбидопы - за 24 часа. Доза препарата Тидомет Форте в этом случае должна составлять не более 20 % от прежней дозы леводопы. Поддерживающая доза составляет 3-6 таблеток в сутки для большинства пациентов.
Полная инструкция
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Тидомет форте таб.
Тидомет форте таб., 250 мг+25 мг, 100 шт.
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3 вопроса
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