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Моксонидин Реневал таб. п/о плен., 0.2 мг, 90 шт.

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4.9
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Дозировка: 0.2 мг

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Количество штук в упаковке, шт.: 90

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Коротко о товаре

Артикул Маркета
4636591438
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии. Коррекция дозы для пациентов с печеночной недостаточностью не требуется. \u003Cbr\u003E\nНачальная доза для пациентов, находящихся на гемодиализе — 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг в сутки. \u003Cbr\u003E\nПациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин)."},{"name":"Побочные действия","value":"Наиболее частые побочные эффекты у пациентов, принимающих моксонидин: сухость во рту, головокружение, астения и сонливость. Эти симптомы часто уменьшаются по прошествии первых недель терапии.\u003Cbr\u003EУ пациентов, принимавших участие в плацебо-контролируемых клинических исследованиях моксонидина, отмечены следующие побочные эффекты. Частота побочных эффектов, приведенных ниже, определялась соответственно следующему: очень часто (\u003E 1/10); часто (\u003E 1/100, \u003C 1/10); нечасто (\u003E 1/1000, \u003C 1/100); включая отельные сообщения.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003E\nЧасто: головная боль , головокружение (вертиго), сонливость, бессонница.\nНечасто: обморок , повышенная возбудимость.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003E\nНечасто: звон в ушах.\u003Cbr\u003EНарушения со стороны сердца\nНечасто: выраженное снижение АД, ортостатическая гипотензия*, брадикардия.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\nОчень часто: сухость во рту. \u003Cbr\u003E\nЧасто: диарея, тошнота, рвота, диспепсия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003E\nЧасто: кожная сыпь, кожный зуд. \u003Cbr\u003E\nНечасто: ангионевротический отек.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани\u003Cbr\u003E\nЧасто: боль в спине. \u003Cbr\u003E\nНечасто: боль в области шеи.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003E\nЧасто: астения. \u003Cbr\u003E\nНечасто: периферические отеки.\u003Cbr\u003E(* — частота сопоставима с плацебо).\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Моксонидин является гипотензивным средством с центральным механизмом действия. В стволовых структурах мозга (ростральный слой боковых желудочков) моксонидин селективно стимулирует имидазолин-чувствительные рецепторы, принимающие участие в тонической и рефлекторной регуляции симпатической нервной системы. Стимуляция имидазолиновых рецепторов снижает периферическую симпатическую активность и артериальное давление (АД).\u003Cbr\u003E\nМоксонидин отличается от других симпатолитических гипотензивных средств более низким сродством к а2-адренорецепторам, что объясняет меньшую вероятность развития седативного эффекта и сухости во рту.\u003Cbr\u003E\nПрием моксонидина приводит к снижению системного сосудистого сопротивления и АД. Антигипертензивный эффект моксонидина подтвержден в двойных слепых плацебо-контролируемых рандомизированных исследованиях.\u003Cbr\u003E\nРезультаты клинического исследования с участием 42 пациентов с артериальной гипертензией гипертрофией левого желудочка (ГЛК) продемонстрировали, что при сходном снижении артериального давления, применение комбинации антагонистов рецепторов к ангиотензину П с моксонидином позволяет в большей степени уменьшить ГЛ)К по сравнению со свободной комбинацией тиазидного диуретика и блокатора кальциевых каналов (15 % против 11%; р \u003C 0,05).\u003Cbr\u003E\nМоксонидин улучшает на 21% индекс чувствительности к инсулину (в сравнении с плацебо) у пациентов с ожирением, инсулинрезистентностью и умеренной степенью артериальной гипертензии."},{"name":"Фармакологическая группа","value":"гипотензивное средство центрального действия"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 30оС.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Передозировка:\u003Cbr\u003EИмеются сообщения о нескольких случаях передозировки без летального исхода, когда одномоментно применялись дозы до 19,6 мг.\u003Cbr\u003EСимптомы\u003Cbr\u003E\nГоловная боль, седативный эффект, сонливость, выраженное снижение АД, головокружение, астения, брадикардия, сухость во рту, рвота, усталость, боль в эпигастральной области, угнетение дыхания и нарушение сознания.\nКроме того, возможны также кратковременное повышение АД, тахикардия и гипергликемия, как было показано в нескольких исследованиях по изучению высоких доз на животных.\u003Cbr\u003EЛечение\u003Cbr\u003E\nСпецифического антидота не существует. В случае выраженного снижения АД может потребоваться восстановление объема циркулирующей крови за счет введения жидкости и допамина (инъекционно). \u003Cbr\u003E\nБрадикардия может быть купирована атропином (инъекционное введение).\nВ тяжелых случаях передозировки рекомендуется тщательно контролировать нарушения сознания и не допускать угнетения дыхания. \u003Cbr\u003E\nАнтагонисты альфа-адренорецепторов могут уменьшать или устранять парадоксальные гипертензивные эффекты при передозировке моксонидином."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003E\nКлинические данные о применении моксонидина у беременных отсутствуют.\nВ ходе исследований на животных было установлено эмбриотоксическое действие препарата. \u003Cbr\u003E\nМоксонидин следует назначать беременным только после тщательной оценки соотношения риска и пользы, когда польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003E\nМоксонидин проникает в грудное молоко и поэтому не должен назначаться во время кормления грудью. При необходимости применения моксонидина в период лактации, грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследования влияния препарат на способность управлять автомобилем и другими механизмами не проводились. \u003Cbr\u003E\nИмеются сообщения о сонливости и головокружении в период лечения моксонидином. \u003Cbr\u003E\nЭто следует учитывать при выполнении вышеуказанных действий."},{"name":"Особые указания","value":"Во время лечения необходим регулярный контроль АД. \u003Cbr\u003E\nВ постмаркетинговом наблюдении зафиксированы случаи атриовентрикулярной блокады различной степени тяжести у пациентов, принимающих моксонидин. Связь между приемом моксонидина и замедлением атриовентрикулярной проводимости не может быть исключена. Таким образом, при лечении пациентов с предрасположенностью к развитию атриовентрикулярной блокады рекомендуется соблюдать осторожность. \u003Cbr\u003E\nПри необходимости отмены одновременно принимаемых бета-адреноблокаторов и моксонидина сначала отменяют бета-адреноблокаторы и лишь через несколько дней моксонидин. \u003Cbr\u003E\nВ настоящее время нет подтверждения того, что прекращение приема моксонидина приводит к повышению АД. \u003Cbr\u003E\nОднако не рекомендуется прекращать прием моксонидина резко, вместо этого следует постепенно уменьшать дозу препарата в течение двух недель.\nУ пациентов пожилого возраста может быть повышен риск развития сердечно-сосудистых осложнений вследствие применения гипотензивных препаратов, поэтому терапию моксонидином следует начитать с минимальной дозы.\u003Cbr\u003EВспомогательные вещества\u003Cbr\u003E\nПрепарат Моксонидин Реневал содержит лактозы моногидрат. Пациентам с редко встречающимися наследственными заболеваниями, такими как непереносимость галактозы, непереносимость лактозы вследствие дефицита лактазы или синдрома глюкозо-галактозной мальабсорбции, не следует принимать данный лекарственный препарат. \u003Cbr\u003E\nПрепарат Моксонидин Реневал содержит краситель Понсо 4R (E124), который может вызывать аллергические реакции\u003Cbr\u003EС осторожностью: Атриовентрикулярная блокада степени (риск развития брадикардии), заболевания коронарных артерий (в том числе ишемическая болезнь сердца, нестабильная стенокардия, ранний постинфарктный период), заболевания периферического кровообращения (в том числе перемежающаяся хромота, синдром Рейно), эпилепсия, болезнь Паркинсона, депрессия, глаукома; умеренная почечная недостаточность (КК 30-60 мл/мин, креатинин сыворотки 105-160 мкмоль/л), печеночная недостаточность; беременность."},{"name":"Взаимодействие","value":"Совместное применение моксонидина с другими гипотензивными средствами приводит к аддитивному эффекту.\u003Cbr\u003EТрициклические антидепрессанты могут снижать эффективность гипотензивных средств центрального действия, в связи с чем не рекомендуется их прием совместно с моксонидином.\u003Cbr\u003EМоксонидин может усиливать седативное действие трициклических антидепрессантов (необходимо избегать совместного назначения), транквилизаторов, этанола, седативных и снотворных средств.\u003Cbr\u003EМоксонидин способен умеренно улучшать ослабленные когнитивные функции у пациентов, получающих лоразепам.\u003Cbr\u003EМоксонидин может усиливать седативный эффект производных бензодиазепина при их одновременном назначении.\u003Cbr\u003EМоксонидин выделяется путем канальцевой секреции. Поэтому не исключено его взаимодействие с другими препаратами, выделяющимися путем канальцевой секреции."},{"name":"Регистрационный номер","value":"ЛП-007079"},{"name":"Дата государственной регистрации","value":"08.06.2021"},{"name":"Владелец регистрационного удостоверения","value":"ПФК Обновление","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:16815730"]}}},{"name":"Изготовитель","value":"ПФК Обновление"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Моксонидин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:17893175"]}}},{"name":"Срок годности","value":"715 дн."}]}},"fullSpecsGrouped":{"186979339829740277":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия"},{"name":"Показания к применению","value":"артериальная гипертензия."},{"name":"Противопоказания","value":"повышенная чувствительность к действующему веществу и другим компонентам препарата;\u003Cbr\u003Eангионевротический отек в анамнезе;\u003Cbr\u003Eсиндром слабости синусового узла или синоатриальная блокада;\u003Cbr\u003Eтяжелая печеночная недостаточность;\u003Cbr\u003Eвыраженная брадикардия (частота сердечных сокращений (ЧСС) покоя менее 50 уд/мин);\u003Cbr\u003Eатриовентрикулярная блокада II или III степени;\u003Cbr\u003Eострая и хроническая сердечная недостаточность;\u003Cbr\u003Eпериод грудного вскармливания;\u003Cbr\u003Eнаследственная непереносимость галактозы, дефицит лактазы или синдром глюкозогалактозной мальабсорбции;\u003Cbr\u003Eвозраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности)."},{"name":"Состав","value":"действующее вещество: моксонидин - 0,2000 мг, 0,4000 мг;\u003Cbr\u003Eвспомогательные вещества: лактозы моногидрат, кроскармеллоза натрия, повидон К 30, магния стеарат; состав оболочки: OPADRY СОMPLETE FILM COATING SYSTEM 13F240000 PINK [гипромеллоза, тальк, титана диоксид, макрогол 6000, полисорбат 80 (твин 80), краситель пунцовый [Понсо 4R] (E124), краситель хинолиновый желтый (E104)]."},{"name":"Действующее вещество","value":"Моксонидин"},{"name":"Способ применения и дозы","value":"Внутрь, независимо от приема пищи. \u003Cbr\u003E\nВ большинстве случаев начальная доза препарата Моксонидин Реневал составляет 0,2 мг в сутки. Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии. Коррекция дозы для пациентов с печеночной недостаточностью не требуется. \u003Cbr\u003E\nНачальная доза для пациентов, находящихся на гемодиализе — 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг в сутки. \u003Cbr\u003E\nПациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин)."},{"name":"Побочные действия","value":"Наиболее частые побочные эффекты у пациентов, принимающих моксонидин: сухость во рту, головокружение, астения и сонливость. Эти симптомы часто уменьшаются по прошествии первых недель терапии.\u003Cbr\u003EУ пациентов, принимавших участие в плацебо-контролируемых клинических исследованиях моксонидина, отмечены следующие побочные эффекты. Частота побочных эффектов, приведенных ниже, определялась соответственно следующему: очень часто (\u003E 1/10); часто (\u003E 1/100, \u003C 1/10); нечасто (\u003E 1/1000, \u003C 1/100); включая отельные сообщения.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003E\nЧасто: головная боль , головокружение (вертиго), сонливость, бессонница.\nНечасто: обморок , повышенная возбудимость.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003E\nНечасто: звон в ушах.\u003Cbr\u003EНарушения со стороны сердца\nНечасто: выраженное снижение АД, ортостатическая гипотензия*, брадикардия.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\nОчень часто: сухость во рту. \u003Cbr\u003E\nЧасто: диарея, тошнота, рвота, диспепсия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003E\nЧасто: кожная сыпь, кожный зуд. \u003Cbr\u003E\nНечасто: ангионевротический отек.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани\u003Cbr\u003E\nЧасто: боль в спине. \u003Cbr\u003E\nНечасто: боль в области шеи.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003E\nЧасто: астения. \u003Cbr\u003E\nНечасто: периферические отеки.\u003Cbr\u003E(* — частота сопоставима с плацебо).\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Моксонидин является гипотензивным средством с центральным механизмом действия. В стволовых структурах мозга (ростральный слой боковых желудочков) моксонидин селективно стимулирует имидазолин-чувствительные рецепторы, принимающие участие в тонической и рефлекторной регуляции симпатической нервной системы. Стимуляция имидазолиновых рецепторов снижает периферическую симпатическую активность и артериальное давление (АД).\u003Cbr\u003E\nМоксонидин отличается от других симпатолитических гипотензивных средств более низким сродством к а2-адренорецепторам, что объясняет меньшую вероятность развития седативного эффекта и сухости во рту.\u003Cbr\u003E\nПрием моксонидина приводит к снижению системного сосудистого сопротивления и АД. Антигипертензивный эффект моксонидина подтвержден в двойных слепых плацебо-контролируемых рандомизированных исследованиях.\u003Cbr\u003E\nРезультаты клинического исследования с участием 42 пациентов с артериальной гипертензией гипертрофией левого желудочка (ГЛК) продемонстрировали, что при сходном снижении артериального давления, применение комбинации антагонистов рецепторов к ангиотензину П с моксонидином позволяет в большей степени уменьшить ГЛ)К по сравнению со свободной комбинацией тиазидного диуретика и блокатора кальциевых каналов (15 % против 11%; р \u003C 0,05).\u003Cbr\u003E\nМоксонидин улучшает на 21% индекс чувствительности к инсулину (в сравнении с плацебо) у пациентов с ожирением, инсулинрезистентностью и умеренной степенью артериальной гипертензии."},{"name":"Фармакологическая группа","value":"гипотензивное средство центрального действия"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 30оС.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Передозировка:\u003Cbr\u003EИмеются сообщения о нескольких случаях передозировки без летального исхода, когда одномоментно применялись дозы до 19,6 мг.\u003Cbr\u003EСимптомы\u003Cbr\u003E\nГоловная боль, седативный эффект, сонливость, выраженное снижение АД, головокружение, астения, брадикардия, сухость во рту, рвота, усталость, боль в эпигастральной области, угнетение дыхания и нарушение сознания.\nКроме того, возможны также кратковременное повышение АД, тахикардия и гипергликемия, как было показано в нескольких исследованиях по изучению высоких доз на животных.\u003Cbr\u003EЛечение\u003Cbr\u003E\nСпецифического антидота не существует. В случае выраженного снижения АД может потребоваться восстановление объема циркулирующей крови за счет введения жидкости и допамина (инъекционно). \u003Cbr\u003E\nБрадикардия может быть купирована атропином (инъекционное введение).\nВ тяжелых случаях передозировки рекомендуется тщательно контролировать нарушения сознания и не допускать угнетения дыхания. \u003Cbr\u003E\nАнтагонисты альфа-адренорецепторов могут уменьшать или устранять парадоксальные гипертензивные эффекты при передозировке моксонидином."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003E\nКлинические данные о применении моксонидина у беременных отсутствуют.\nВ ходе исследований на животных было установлено эмбриотоксическое действие препарата. \u003Cbr\u003E\nМоксонидин следует назначать беременным только после тщательной оценки соотношения риска и пользы, когда польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003E\nМоксонидин проникает в грудное молоко и поэтому не должен назначаться во время кормления грудью. При необходимости применения моксонидина в период лактации, грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследования влияния препарат на способность управлять автомобилем и другими механизмами не проводились. \u003Cbr\u003E\nИмеются сообщения о сонливости и головокружении в период лечения моксонидином. \u003Cbr\u003E\nЭто следует учитывать при выполнении вышеуказанных действий."},{"name":"Особые указания","value":"Во время лечения необходим регулярный контроль АД. \u003Cbr\u003E\nВ постмаркетинговом наблюдении зафиксированы случаи атриовентрикулярной блокады различной степени тяжести у пациентов, принимающих моксонидин. Связь между приемом моксонидина и замедлением атриовентрикулярной проводимости не может быть исключена. Таким образом, при лечении пациентов с предрасположенностью к развитию атриовентрикулярной блокады рекомендуется соблюдать осторожность. \u003Cbr\u003E\nПри необходимости отмены одновременно принимаемых бета-адреноблокаторов и моксонидина сначала отменяют бета-адреноблокаторы и лишь через несколько дней моксонидин. \u003Cbr\u003E\nВ настоящее время нет подтверждения того, что прекращение приема моксонидина приводит к повышению АД. \u003Cbr\u003E\nОднако не рекомендуется прекращать прием моксонидина резко, вместо этого следует постепенно уменьшать дозу препарата в течение двух недель.\nУ пациентов пожилого возраста может быть повышен риск развития сердечно-сосудистых осложнений вследствие применения гипотензивных препаратов, поэтому терапию моксонидином следует начитать с минимальной дозы.\u003Cbr\u003EВспомогательные вещества\u003Cbr\u003E\nПрепарат Моксонидин Реневал содержит лактозы моногидрат. Пациентам с редко встречающимися наследственными заболеваниями, такими как непереносимость галактозы, непереносимость лактозы вследствие дефицита лактазы или синдрома глюкозо-галактозной мальабсорбции, не следует принимать данный лекарственный препарат. \u003Cbr\u003E\nПрепарат Моксонидин Реневал содержит краситель Понсо 4R (E124), который может вызывать аллергические реакции\u003Cbr\u003EС осторожностью: Атриовентрикулярная блокада степени (риск развития брадикардии), заболевания коронарных артерий (в том числе ишемическая болезнь сердца, нестабильная стенокардия, ранний постинфарктный период), заболевания периферического кровообращения (в том числе перемежающаяся хромота, синдром Рейно), эпилепсия, болезнь Паркинсона, депрессия, глаукома; умеренная почечная недостаточность (КК 30-60 мл/мин, креатинин сыворотки 105-160 мкмоль/л), печеночная недостаточность; беременность."},{"name":"Взаимодействие","value":"Совместное применение моксонидина с другими гипотензивными средствами приводит к аддитивному эффекту.\u003Cbr\u003EТрициклические антидепрессанты могут снижать эффективность гипотензивных средств центрального действия, в связи с чем не рекомендуется их прием совместно с моксонидином.\u003Cbr\u003EМоксонидин может усиливать седативное действие трициклических антидепрессантов (необходимо избегать совместного назначения), транквилизаторов, этанола, седативных и снотворных средств.\u003Cbr\u003EМоксонидин способен умеренно улучшать ослабленные когнитивные функции у пациентов, получающих лоразепам.\u003Cbr\u003EМоксонидин может усиливать седативный эффект производных бензодиазепина при их одновременном назначении.\u003Cbr\u003EМоксонидин выделяется путем канальцевой секреции. Поэтому не исключено его взаимодействие с другими препаратами, выделяющимися путем канальцевой секреции."},{"name":"Регистрационный номер","value":"ЛП-007079"},{"name":"Дата государственной регистрации","value":"08.06.2021"},{"name":"Владелец регистрационного удостоверения","value":"ПФК Обновление"},{"name":"Изготовитель","value":"ПФК Обновление"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Моксонидин"},{"name":"Срок годности","value":"715 дн."}]}],"transitionId":"tr_5152863119645058917"}}}}
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378 ₽

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Вместо:428 ₽
  • 11-13 июня, самовывоз • 0 ₽
POLZAru
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  • Моксонидин Канон таб. п/о плен., 0.4 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-d7ydltwizpj/toggleWishlist":{"skuId":"186557801","productId":1401075448,"offerId":"Su2mRI_bKvYwvVzuGwMvVg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQmrius+LZneyDARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIVCPjtipwFEOnK+lgYzsLZByDX3MEH","sign":"FYe3MasmBRH7H6TeD2qcCe05VH0N4IKCJ9n/gcZVDTI="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-d7ydltwizpj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин Канон таб. п/о плен., 0.4 мг, 28 шт.

    Рейтинг товара: 4.7 из 5
    на основе 23 оценки
    Цена 216 ₽
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  • Моксонидин таб. п/о плен., 0.4 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-4qlz0qijk1w/toggleWishlist":{"skuId":"101872314826","productId":1784965285,"offerId":"Q6cpc41UW3lkQGTNipywHg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQmrius+LZneyDARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCKXRkdMGEMrTwMD7AhiXtvsFINfcwQc=","sign":"6DRUoadLPlaF6pGrj69sjHA8qAN7snouo78/Am3t3EQ="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-4qlz0qijk1w/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин таб. п/о плен., 0.4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 23 оценки
    Цена 239 ₽
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  • Моксонидин таб. п/о плен., 0.2 мг, 14 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mpf3mak5kn/toggleWishlist":{"skuId":"228052574","productId":1401075651,"offerId":"Bfs2xETKc8qIaMQWqYOUeA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQmrius+LZneyDARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIVCMPvipwFEN6c32wYhKmyCCDX3MEH","sign":"jqrCy2faaXtDjMeRw4WmYHqD5SFeMYNtiLpj4BNUck0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mpf3mak5kn/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин таб. п/о плен., 0.2 мг, 14 шт.

    Рейтинг товара: 5 из 5
    на основе 30 оценок
    Цена 148 ₽
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  • Моксонидин-АЛСИ таб. п/о плен., 0.2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6u17z0g1ayt/toggleWishlist":{"skuId":"101474629555","productId":1460168636,"offerId":"YsfCv0uxuqmEj4FmXIZzIA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQmrius+LZneyDARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCLzPobgFELPv74L6AhjH3NAHINfcwQc=","sign":"Md/JSGCPGVEsOuT5uOa2HSZjxxxgjPU8u6uefMQ4zFE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6u17z0g1ayt/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин-АЛСИ таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 8 оценок
    Цена 177 ₽
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  • Моксонидин-Алиум таб. п/о плен., 200 мкг, 14 шт., 1
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    Моксонидин-Алиум таб. п/о плен., 200 мкг, 14 шт., 1

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 89 ₽
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  • Моксонидин-Акрихин таб. п/о плен., 0.2 мг, 30 шт.
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    Моксонидин-Акрихин таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 6 оценок
    Цена 249 ₽
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  • Моксонитекс таб. п/о плен., 0.2 мг, 28 шт.
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    Моксонитекс таб. п/о плен., 0.2 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 319 ₽
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  • Моксонидин Авексима таб. п/о плен., 0.2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ycguff71ol/toggleWishlist":{"skuId":"101392286737","productId":664975014,"offerId":"72zz_9k4YDjBbIX2EojDtw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQmrius+LZneyDARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCKbtir0CEJGIztv5AhjUqdgHINfcwQc=","sign":"X2EMBAfywNhP883kWu49KgIvIWnqmbJUbNq689KR7ro="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ycguff71ol/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин Авексима таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 7 оценок
    Цена 281 ₽
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  • Бисопролол Реневал таб. п/о плен., 5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-96hjxs473yg/toggleWishlist":{"skuId":"101762663758","productId":1754834159,"offerId":"6_EmMXajAMKDm99g_CYjaQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQmrius+LZneyDARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCO/J4sQGEM6KnIz7AhjyrIIIINfcwQc=","sign":"TbkBRt1csxEWhAUCwK5JQ16disGUp63lnpcNGMfRvTE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-96hjxs473yg/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Бисопролол Реневал таб. п/о плен., 5 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 45 оценок
    Цена 99 ₽
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Инструкция

Показания к применению

артериальная гипертензия.

Противопоказания

повышенная чувствительность к действующему веществу и другим компонентам препарата;
ангионевротический отек в анамнезе;
синдром слабости синусового узла или синоатриальная блокада;
тяжелая печеночная недостаточность;
выраженная брадикардия (частота сердечных сокращений (ЧСС) покоя менее 50 уд/мин);
атриовентрикулярная блокада II или III степени;
острая и хроническая сердечная недостаточность;
период грудного вскармливания;
наследственная непереносимость галактозы, дефицит лактазы или синдром глюкозогалактозной мальабсорбции;
возраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности).

Способ применения и дозы

Внутрь, независимо от приема пищи.
В большинстве случаев начальная доза препарата Моксонидин Реневал составляет 0,2 мг в сутки. Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии. Коррекция дозы для пациентов с печеночной недостаточностью не требуется.
Начальная доза для пациентов, находящихся на гемодиализе — 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг в сутки.
Пациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин).
Полная инструкция
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Моксонидин Реневал таб. п/о плен.
Моксонидин Реневал таб. п/о плен., 0.2 мг, 90 шт.
4.9
(12)
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Задать вопрос
Инструкция

378 ₽

Скидка: 12%
–12 %
Вместо:428 ₽
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4.9
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У продавца:12 оценок·4 отзыва
У всех продавцов:43 оценки·15 отзывов
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user avatar
Месяц назад • Наталия М. • Куплен на Маркете
Достоинства: Помогает при высоком давлении
Недостатки: Нет
Комментарий: Хороший препарат, рекомендую.
user avatar
4 дня назад • Лидия Батова • Куплен на Маркете
Комментарий: "Скорая помощь" при высоком давлении. Выписал врач.
user avatar
2 месяца назад • Дмитрий Захаров • Куплен на Маркете
Комментарий: беру второй раз,помогает....вроде .каждому своё !
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