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Описание

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Метронидазол Реневал таб., 250 мг, 24 шт.

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5.0
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Коротко о товаре

Артикул Маркета
3123167471
Тип препарата
Назначение
абсцессы, амебиаз, бактериальные инфекции ЦНС, бактериальные инфекции костной и соединительной ткани, бактериальные инфекции органов брюшной полости и гепатобилиарной системы, бактериальный менингит, бактериальный эндокардит, пневмония, протозойные инфекции, профилактика послеоперационных осложнений, трихомониаз, эмпиема, язвенная болезнь желудка и 12-перстной кишки, ассоциированная с Helicobacter pylori (в составе комбинированной терапии)
Действующее вещество
Возраст
от 6 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"12034363978401216214":{"specItems":[{"name":"Артикул Маркета","value":"3123167471","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"абсцессы, амебиаз, бактериальные инфекции ЦНС, бактериальные инфекции костной и соединительной ткани, бактериальные инфекции органов брюшной полости и гепатобилиарной системы, бактериальный менингит, бактериальный эндокардит, пневмония, протозойные инфекции, профилактика послеоперационных осложнений, трихомониаз, эмпиема, язвенная болезнь желудка и 12-перстной кишки, ассоциированная с Helicobacter pylori (в составе комбинированной терапии)","transition":{"type":"list","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["36476390:36618912,36618778,36618687,36618619,36618541,36618526,36618519,36618390,36618289,36617565,36617546,36617298,36617284"]}}},{"name":"действующее вещество","value":"Метронидазол","transition":{"type":"list","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28708554"]}}},{"name":"возраст","value":"от 6 лет"},{"name":"форма выпуска","value":"таблетки"},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"12034363978401216214":{"specItems":[{"name":"Артикул Маркета","value":"3123167471","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Действующее вещество","value":"Метронидазол","transition":{"type":"list","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28708554"]}}},{"name":"Возраст","value":"От 6 лет"},{"name":"Форма выпуска","value":"Таблетки"}]}},"fullSpecs":{"12034363978401216214":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27272850:1,0"]}}},{"name":"Назначение","value":"абсцессы, амебиаз, бактериальные инфекции ЦНС, бактериальные инфекции костной и соединительной ткани, бактериальные инфекции органов брюшной полости и гепатобилиарной системы, бактериальный менингит, бактериальный эндокардит, пневмония, протозойные инфекции, профилактика послеоперационных осложнений, трихомониаз, эмпиема, язвенная болезнь желудка и 12-перстной кишки, ассоциированная с Helicobacter pylori (в составе комбинированной терапии)","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["36476390:36618912,36618778,36618687,36618619,36618541,36618526,36618519,36618390,36618289,36617565,36617546,36617298,36617284"]}}},{"name":"Органы и системы","value":"дыхательная система, опорно-двигательная система, пищеварительная система, половая система"},{"name":"Показания к применению","value":"• Протозойные инфекции: внекишечный амебиаз (включая амебный абсцесс печени),\u003Cbr\u003Eкишечный амебиаз (амебная дизентерия), трихомониаз.\u003Cbr\u003E• Инфекции, вызываемые Bacteroides spp. (в том числе B. fragilis, B. distasonis,\u003Cbr\u003EB. ovatus, B. thetaiotaomicron, B. vulgatus); инфекции костей и суставов; инфекции центральной\u003Cbr\u003Eнервной системы (ЦНС), в том числе менингит, абсцесс мозга; бактериальный эндокардит;\u003Cbr\u003Eпневмония, эмпиема и абсцесс легких; сепсис.\u003Cbr\u003E• Инфекции, вызываемые Clostridium spp., Peptococcus niger, Peptostreptococcus spp.: инфекции\u003Cbr\u003Eбрюшной полости (перитонит, абсцесс печени), инфекции органов малого таза (эндометрит,\u003Cbr\u003Eабсцесс фаллопиевых труб и яичников, инфекции свода влагалища).\u003Cbr\u003E• Псевдомембранозный колит, связанный с применением антибиотиков.\u003Cbr\u003E• Гастрит или язва двенадцатиперстной кишки, связанные с Helicobacter pylori (в составе\u003Cbr\u003Eкомплексной терапии).\u003Cbr\u003E• Профилактика послеоперационных осложнений (особенно после операций на ободочной\u003Cbr\u003Eкишке, в параректальной области, аппендэктомии, гинекологических операций)."},{"name":"Противопоказания","value":"Гиперчувствительность к метронидазолу, к другим производным нитроимидазола, к имидазолам\u003Cbr\u003Eи к другим компонентам препарата; органические поражения ЦНС (в том числе эпилепсия);\u003Cbr\u003Eлейкопения (в том числе в анамнезе); печеночная недостаточность (в случае назначения больших\u003Cbr\u003Eдоз); беременность, период лактации; детский возраст до 6 лет."},{"name":"Состав","value":"Состав на одну таблетку\u003Cbr\u003EДействующее вещество: метронидазол – 250,0 мг; вспомогательные вещества: крахмал картофельный, стеариновая кислота, тальк."},{"name":"Действующее вещество","value":"Метронидазол","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28708554"]}}},{"name":"Способ применения и дозы","value":"Метронидазол принимают внутрь, до или после еды, запивая достаточным количеством воды.\u003Cbr\u003EПри кишечном амебиазе метронидазол применяют в суточной дозе 1500 мг (разделенной на 3\u003Cbr\u003Eприема) в течение 7 дней.\u003Cbr\u003EПри острой амебной дизентерии суточная доза составляет 2250 мг (разделенная на 3 приема).\u003Cbr\u003EДетям от 6 до 15 лет назначают суточную дозу 500 мг (разделенную на 2 приема).\u003Cbr\u003EПри абсцессе печени и других внекишечных формах амебиаза максимальная суточная доза\u003Cbr\u003Eсоставляет 2500 мг (разделенная на 3 приема) в течение 3-5 дней, в комбинации с\u003Cbr\u003Eтетрациклиновыми антибиотиками и другими методами терапии. Детям от 6 до 15 лет назначают\u003Cbr\u003Eсуточную дозу 500 мг (разделенную на 2 приема).\u003Cbr\u003EПри трихомониазе у женщин (уретрит и вагинит) метронидазол назначают однократно в дозе 2 г\u003Cbr\u003Eили в виде курсового лечения по 250 мг 2 раза в сутки в течение 10 дней.\u003Cbr\u003EПри трихомониазе у мужчин (уретрит) метронидазол назначают однократно в дозе 2 г или в\u003Cbr\u003Eвиде курсового лечения по 250 мг 2 раза в сутки в течение 10 дней.\u003Cbr\u003EЛечение анаэробных инфекций обычно начинают с внутривенных инфузий с последующим\u003Cbr\u003Eпереходом на таблетки. Для взрослых доза препарата составляет 500 мг 3 раза в сутки. Длительность\u003Cbr\u003Eлечения составляет до 7 дней.\u003Cbr\u003EДля лечения псевдомембранозного колита метронидазол назначают по 500 мг 3-4 раза в сутки.\u003Cbr\u003EДлительность лечения определяется врачом.\u003Cbr\u003EДля эрадикации Helicobacter pylori метронидазол назначают по 500 мг 3 раза в сутки в составе\u003Cbr\u003Eкомбинированной терапии (например, с амоксициллином).\u003Cbr\u003EДля профилактики послеоперационных осложнений метронидазол назначают в суточной дозе\u003Cbr\u003E750-1500 мг (разделенной на 3 приема) за 3-4 дня до операции. Через 1-2 дня после операции\u003Cbr\u003E(когда уже разрешен прием внутрь) метронидазол назначают по 750 мг в сутки в течение 7 дней."},{"name":"Побочные действия","value":"Нарушения со стороны желудочно-кишечного тракта\u003Cbr\u003E• Боли в эпигастрии, тошнота, рвота, диарея.\u003Cbr\u003E• Воспаление слизистой оболочки полости рта (глоссит, стоматит), нарушения вкусовых\u003Cbr\u003Eощущений («металлический» привкус во рту), снижение аппетита, анорексия, сухость слизистой\u003Cbr\u003Eоболочки полости рта, запор.\u003Cbr\u003E• Панкреатит (обратимые случаи).\u003Cbr\u003E• Изменение цвета языка / «обложенный» язык (из-за чрезмерного роста грибковой\u003Cbr\u003Eмикрофлоры).\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003E• Ангионевротический отек, анафилактический шок.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003E• Периферическая сенсорная нейропатия.\u003Cbr\u003E• Головная боль, судороги, головокружение.\u003Cbr\u003E• Сообщалось о развитии энцефалопатии (например, спутанность сознания) и подострого\u003Cbr\u003Eмозжечкового синдрома (нарушение координации и синергизма движений, атаксия, дизартрия,\u003Cbr\u003Eнарушения походки, нистагм и тремор), которые подвергаются обратному развитию после отмены\u003Cbr\u003Eметронидазола.\u003Cbr\u003E• Асептический менингит.\u003Cbr\u003EНарушения психики\u003Cbr\u003E• Психотические расстройства, включая спутанность сознания, галлюцинации.\u003Cbr\u003E• Депрессия, бессонница, раздражительность, повышенная возбудимость.\u003Cbr\u003EНарушения со стороны органа зрения\u003Cbr\u003E• Преходящие нарушения зрения, такие как диплопия, миопия, нечеткость зрения,\u003Cbr\u003Eснижение остроты зрения, нарушение цветового восприятия.\u003Cbr\u003E• Нейропатия/неврит зрительного нерва.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003E• Нарушения слуха/потеря слуха (включая нейросенсорную глухоту).\u003Cbr\u003E• Шум в ушах.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы\u003Cbr\u003E• Агранулоцитоз, лейкопения, нейтропения и тромбоцитопения.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003E• Повышение активности «печеночных» ферментов (аспартатаминотрансферазы (АСТ) и\u003Cbr\u003Eаланинаминотрансферазы (АЛТ), щелочной фосфатазы), развитие холестатического или смешанного гепатита, гепатоцеллюлярного поражения печени, иногда сопровождавшегося\u003Cbr\u003Eжелтухой.\u003Cbr\u003E• У пациентов, получавших лечение метронидазолом в комбинации с другими\u003Cbr\u003Eантибиотиками, наблюдались случаи развития печеночной недостаточности, потребовавшей\u003Cbr\u003Eпроведения трансплантации печени.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003E• Сыпь, зуд, приливы крови к кожным покровам, гиперемия кожи, крапивница.\u003Cbr\u003E• Пустулезная кожная сыпь.\u003Cbr\u003E• Фиксированная лекарственная сыпь.\u003Cbr\u003E• Синдром Стивенса-Джонсона, токсический эпидермальный некролиз.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003E• Возможно окрашивание мочи в коричнево-красноватый цвет, обусловленное наличием в\u003Cbr\u003Eмоче водорастворимого метаболита метронидазола.\u003Cbr\u003E• Дизурия, полиурия, цистит, недержание мочи, кандидоз.\u003Cbr\u003EОбщие расстройства\u003Cbr\u003E• Лихорадка, заложенность носа, артралгии, слабость.\u003Cbr\u003EЛабораторные и инструментальные данные\u003Cbr\u003E• Уплощение зубца Т на ЭКГ."},{"name":"Фармакологическое действие","value":"Метронидазол является производным 5-нитроимидазола. Механизм действия заключается в биохимическом восстановлении 5-нитрогруппы внутриклеточными транспортными протеинами анаэробных микроорганизмов и простейших. Восстановленная 5-нитрогруппа взаимодействует с дезоксирибонуклеиновой кислотой (ДНК) клетки микроорганизмов, ингибируя синтез их нуклеиновых кислот, что ведет к гибели бактерий.\u003Cbr\u003EАктивен в отношении Trichomonas vaginalis, Entamoeba histolytica, а также грамотрицательных анаэробов Bacteroides spp. (в т.ч. Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp. и некоторых грамположительных анаэробов (чувствительные штаммы Eubacterium spp., Clostridium spp., Peptococcus niger., Peptostreptococcus spp.). Минимальная подавляющая концентрация для этих штаммов составляет 0,125-6,25 мкг/мл.\u003Cbr\u003EВ сочетании с амоксициллином проявляет активность в отношении Helicobacter pylori (амоксициллин подавляет развитие резистентности к метронидазолу).\u003Cbr\u003EК метронидазолу не чувствительны аэробные микроорганизмы и факультативные анаэробы, но в присутствии смешанной флоры (аэробы и анаэробы) метронидазол действует синергически с антибиотиками, эффективными против обычных аэробов."},{"name":"Фармакологическая группа","value":"противомикробное и противопротозойное средство"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 6 лет"},{"name":"Условия хранения","value":"В оригинальной упаковке (контурная ячейковая упаковка в пачке) при температуре не выше 30 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Сообщалось о приеме внутрь разовых доз метронидазола до 12 г при суицидальных попытках и\u003Cbr\u003Eслучайных передозировках.\u003Cbr\u003EСимптомы: рвота, атаксия, небольшая дезориентация.\u003Cbr\u003EЛечение: специфического антидота при передозировке метронидазолом не существует. В случае\u003Cbr\u003Eподозрения на значительное превышение дозы следует проводить симптоматическую и\u003Cbr\u003Eподдерживающую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Поскольку метронидазол проходит через плацентарный барьер и его действие на органогенез плода человека неизвестно, применение препарата Метронидазол Реневал во время беременности противопоказано.\u003Cbr\u003EМетронидазол проникает в грудное молоко, поэтому применение препарата в период грудного вскармливания противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Учитывая риск развития таких побочных реакций, как спутанность сознания, головокружение, галлюцинации, нарушения зрения, рекомендуется во время лечения воздержаться от управления автомобилем, от занятий другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Поскольку одновременный прием метронидазола с алкоголем (этанолом) может оказывать эффект, аналогичный эффекту дисульфирама (гиперемия кожных покровов, приливы крови к кожным покровам, рвота, тахикардия), следует предупредить пациентов о том, что во время лечения и в течение хотя бы одного дня после окончания применения препарата не следует употреблять алкогольные напитки или лекарственные препараты, содержащие этанол.\u003Cbr\u003EСледует тщательно взвешивать показания для длительного приема препарата (более 10 дней) и при отсутствии строгих показаний избегать его длительного применения. Если при наличии строгих показаний (тщательно взвесив соотношение между ожидаемым эффектом и потенциальным риском возникновения осложнений), препарат применяется более длительно, чем это обычно рекомендуется, то лечение следует проводить под контролем гематологических показателей (особенно лейкоцитов) и побочных реакций, таких как периферическая или центральная нейропатия, проявляющихся парестезиями, атаксией, головокружением, судорогами, при появлении которых лечение должно быть прекращено.\u003Cbr\u003EПри лечении трихомонадного вагинита у женщин и трихомонадного уретрита у мужчин необходимо воздерживаться от половых контактов. Обязательно одновременное лечение половых партнеров. Лечение не прекращается во время менструаций. После терапии трихомониаза следует провести контрольные пробы в течение 3 очередных циклов до и после менструации.\u003Cbr\u003EСообщалось о развитии тяжелой гепатотоксичности / острой печеночной недостаточности (включая случаи с летальным исходом) у пациентов с синдромом Коккейна. Следует с\u003Cbr\u003Eосторожностью и только в случае отсутствия альтернативного лечения применять метронидазол у данной категории пациентов.\u003Cbr\u003EИсследования функции печени следует проводить в начале лечения, во время лечения и в течение 2 недель после окончания лечения.\u003Cbr\u003EПациентам с синдромом Коккейна следует рекомендовать немедленно сообщать врачу о развитии любых симптомов потенциального поражения печени (таких как впервые выявленная сохраняющаяся боль в животе, анорексия, тошнота, рвота, лихорадка, недомогание, желтуха, потемнение мочи или кожный зуд).\u003Cbr\u003EНеобходимо принимать во внимание, что метронидазол может иммобилизировать трепонемы, что приводит к ложноположительному тесту Нельсона.\u003Cbr\u003EС осторожностью\u003Cbr\u003EПеченочная энцефалопатия; острые и хронические заболевания периферической и центральной\u003Cbr\u003Eнервной системы (риск утяжеления неврологической симптоматики); почечная недостаточность."},{"name":"Взаимодействие","value":"С дисульфирамом\u003Cbr\u003EСообщалось о развитии психотических реакций у пациентов, получавших одновременно\u003Cbr\u003Eметронидазол и дисульфирам (интервал между применением этих лекарственных препаратов\u003Cbr\u003Eдолжен быть не менее 2 недель).\u003Cbr\u003EС этанолом\u003Cbr\u003EВозможно возникновение дисульфирамоподобных реакций (гиперемия кожных покровов,\u003Cbr\u003Eприливы крови к кожным покровам, рвота, тахикардия).\u003Cbr\u003EС непрямыми антикоагулянтами (варфарин)\u003Cbr\u003EУсиление антикоагулянтного эффекта и повышение риска развития кровотечения, связанного со\u003Cbr\u003Eснижением печеночного метаболизма непрямых антикоагулянтов, что может приводить к\u003Cbr\u003Eудлинению протромбинового времени. В случае одновременного применения метронидазола и\u003Cbr\u003Eнепрямых антикоагулянтов требуется более частый контроль протромбинового времени и при\u003Cbr\u003Eнеобходимости коррекция доз антикоагулянтов.\u003Cbr\u003EС препаратами лития\u003Cbr\u003EПри одновременном применении метронидазола с препаратами лития может повышаться\u003Cbr\u003Eконцентрация последнего в плазме крови. При одновременном применении следует\u003Cbr\u003Eконтролировать концентрации лития, креатинина и электролитов в плазме крови.\u003Cbr\u003EС циклоспорином\u003Cbr\u003EПри одновременном применении метронидазола с циклоспорином может повышаться\u003Cbr\u003Eконцентрация циклоспорина в плазме крови. В случае необходимости одновременного\u003Cbr\u003Eприменения метронидазола и циклоспорина следует контролировать концентрации циклоспорина\u003Cbr\u003Eи креатинина в плазме крови.\u003Cbr\u003EС циметидином\u003Cbr\u003EЦиметидин ингибирует метаболизм метронидазола, что может привести к повышению его\u003Cbr\u003Eконцентрации в плазме крови и увеличению риска развития побочных явлений.\u003Cbr\u003EС лекарственными препаратами, индуцирующими изоферменты микросомального окисления в\u003Cbr\u003Eпечени (фенобарбитал, фенитоин)\u003Cbr\u003EОдновременное применение метронидазола с лекарственными препаратами, индуцирующими\u003Cbr\u003Eизоферменты микросомального окисления в печени (фенобарбитал, фенитоин), может ускорять\u003Cbr\u003Eвыведение метронидазола, в результате чего снижается его концентрация в плазме крови.\u003Cbr\u003EС фторурацилом\u003Cbr\u003EМетронидазол уменьшает клиренс фторурацила, приводя к увеличению его токсичности.\u003Cbr\u003EС бусульфаном\u003Cbr\u003EМетронидазол повышает концентрацию бусульфана в плазме крови, что может приводить к\u003Cbr\u003Eразвитию тяжелого токсического действия бусульфана.\u003Cbr\u003EС недеполяризующими миорелаксантами (векурония бромид)\u003Cbr\u003EНе рекомендуется применять с недеполяризующими миорелаксантами (векурония бромид).\u003Cbr\u003EС сульфаниламидами\u003Cbr\u003EСульфаниламиды усиливают противомикробное действие метронидазола."},{"name":"Регистрационный номер","value":"ЛC-002069"},{"name":"Дата государственной регистрации","value":"04.03.2021"},{"name":"Владелец регистрационного удостоверения","value":"ПФК Обновление","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["34324371:35649313","7893318:16815730"]}}},{"name":"Изготовитель","value":"ПФК Обновление"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Метронидазол","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["17796364:18036848"]}}},{"name":"Срок годности","value":"37 мес."}]}},"fullSpecsGrouped":{"12034363978401216214":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Назначение","value":"абсцессы, амебиаз, бактериальные инфекции ЦНС, бактериальные инфекции костной и соединительной ткани, бактериальные инфекции органов брюшной полости и гепатобилиарной системы, бактериальный менингит, бактериальный эндокардит, пневмония, протозойные инфекции, профилактика послеоперационных осложнений, трихомониаз, эмпиема, язвенная болезнь желудка и 12-перстной кишки, ассоциированная с Helicobacter pylori (в составе комбинированной терапии)"},{"name":"Органы и системы","value":"дыхательная система, опорно-двигательная система, пищеварительная система, половая система"},{"name":"Показания к применению","value":"• Протозойные инфекции: внекишечный амебиаз (включая амебный абсцесс печени),\u003Cbr\u003Eкишечный амебиаз (амебная дизентерия), трихомониаз.\u003Cbr\u003E• Инфекции, вызываемые Bacteroides spp. (в том числе B. fragilis, B. distasonis,\u003Cbr\u003EB. ovatus, B. thetaiotaomicron, B. vulgatus); инфекции костей и суставов; инфекции центральной\u003Cbr\u003Eнервной системы (ЦНС), в том числе менингит, абсцесс мозга; бактериальный эндокардит;\u003Cbr\u003Eпневмония, эмпиема и абсцесс легких; сепсис.\u003Cbr\u003E• Инфекции, вызываемые Clostridium spp., Peptococcus niger, Peptostreptococcus spp.: инфекции\u003Cbr\u003Eбрюшной полости (перитонит, абсцесс печени), инфекции органов малого таза (эндометрит,\u003Cbr\u003Eабсцесс фаллопиевых труб и яичников, инфекции свода влагалища).\u003Cbr\u003E• Псевдомембранозный колит, связанный с применением антибиотиков.\u003Cbr\u003E• Гастрит или язва двенадцатиперстной кишки, связанные с Helicobacter pylori (в составе\u003Cbr\u003Eкомплексной терапии).\u003Cbr\u003E• Профилактика послеоперационных осложнений (особенно после операций на ободочной\u003Cbr\u003Eкишке, в параректальной области, аппендэктомии, гинекологических операций)."},{"name":"Противопоказания","value":"Гиперчувствительность к метронидазолу, к другим производным нитроимидазола, к имидазолам\u003Cbr\u003Eи к другим компонентам препарата; органические поражения ЦНС (в том числе эпилепсия);\u003Cbr\u003Eлейкопения (в том числе в анамнезе); печеночная недостаточность (в случае назначения больших\u003Cbr\u003Eдоз); беременность, период лактации; детский возраст до 6 лет."},{"name":"Состав","value":"Состав на одну таблетку\u003Cbr\u003EДействующее вещество: метронидазол – 250,0 мг; вспомогательные вещества: крахмал картофельный, стеариновая кислота, тальк."},{"name":"Действующее вещество","value":"Метронидазол"},{"name":"Способ применения и дозы","value":"Метронидазол принимают внутрь, до или после еды, запивая достаточным количеством воды.\u003Cbr\u003EПри кишечном амебиазе метронидазол применяют в суточной дозе 1500 мг (разделенной на 3\u003Cbr\u003Eприема) в течение 7 дней.\u003Cbr\u003EПри острой амебной дизентерии суточная доза составляет 2250 мг (разделенная на 3 приема).\u003Cbr\u003EДетям от 6 до 15 лет назначают суточную дозу 500 мг (разделенную на 2 приема).\u003Cbr\u003EПри абсцессе печени и других внекишечных формах амебиаза максимальная суточная доза\u003Cbr\u003Eсоставляет 2500 мг (разделенная на 3 приема) в течение 3-5 дней, в комбинации с\u003Cbr\u003Eтетрациклиновыми антибиотиками и другими методами терапии. Детям от 6 до 15 лет назначают\u003Cbr\u003Eсуточную дозу 500 мг (разделенную на 2 приема).\u003Cbr\u003EПри трихомониазе у женщин (уретрит и вагинит) метронидазол назначают однократно в дозе 2 г\u003Cbr\u003Eили в виде курсового лечения по 250 мг 2 раза в сутки в течение 10 дней.\u003Cbr\u003EПри трихомониазе у мужчин (уретрит) метронидазол назначают однократно в дозе 2 г или в\u003Cbr\u003Eвиде курсового лечения по 250 мг 2 раза в сутки в течение 10 дней.\u003Cbr\u003EЛечение анаэробных инфекций обычно начинают с внутривенных инфузий с последующим\u003Cbr\u003Eпереходом на таблетки. Для взрослых доза препарата составляет 500 мг 3 раза в сутки. Длительность\u003Cbr\u003Eлечения составляет до 7 дней.\u003Cbr\u003EДля лечения псевдомембранозного колита метронидазол назначают по 500 мг 3-4 раза в сутки.\u003Cbr\u003EДлительность лечения определяется врачом.\u003Cbr\u003EДля эрадикации Helicobacter pylori метронидазол назначают по 500 мг 3 раза в сутки в составе\u003Cbr\u003Eкомбинированной терапии (например, с амоксициллином).\u003Cbr\u003EДля профилактики послеоперационных осложнений метронидазол назначают в суточной дозе\u003Cbr\u003E750-1500 мг (разделенной на 3 приема) за 3-4 дня до операции. Через 1-2 дня после операции\u003Cbr\u003E(когда уже разрешен прием внутрь) метронидазол назначают по 750 мг в сутки в течение 7 дней."},{"name":"Побочные действия","value":"Нарушения со стороны желудочно-кишечного тракта\u003Cbr\u003E• Боли в эпигастрии, тошнота, рвота, диарея.\u003Cbr\u003E• Воспаление слизистой оболочки полости рта (глоссит, стоматит), нарушения вкусовых\u003Cbr\u003Eощущений («металлический» привкус во рту), снижение аппетита, анорексия, сухость слизистой\u003Cbr\u003Eоболочки полости рта, запор.\u003Cbr\u003E• Панкреатит (обратимые случаи).\u003Cbr\u003E• Изменение цвета языка / «обложенный» язык (из-за чрезмерного роста грибковой\u003Cbr\u003Eмикрофлоры).\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003E• Ангионевротический отек, анафилактический шок.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003E• Периферическая сенсорная нейропатия.\u003Cbr\u003E• Головная боль, судороги, головокружение.\u003Cbr\u003E• Сообщалось о развитии энцефалопатии (например, спутанность сознания) и подострого\u003Cbr\u003Eмозжечкового синдрома (нарушение координации и синергизма движений, атаксия, дизартрия,\u003Cbr\u003Eнарушения походки, нистагм и тремор), которые подвергаются обратному развитию после отмены\u003Cbr\u003Eметронидазола.\u003Cbr\u003E• Асептический менингит.\u003Cbr\u003EНарушения психики\u003Cbr\u003E• Психотические расстройства, включая спутанность сознания, галлюцинации.\u003Cbr\u003E• Депрессия, бессонница, раздражительность, повышенная возбудимость.\u003Cbr\u003EНарушения со стороны органа зрения\u003Cbr\u003E• Преходящие нарушения зрения, такие как диплопия, миопия, нечеткость зрения,\u003Cbr\u003Eснижение остроты зрения, нарушение цветового восприятия.\u003Cbr\u003E• Нейропатия/неврит зрительного нерва.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003E• Нарушения слуха/потеря слуха (включая нейросенсорную глухоту).\u003Cbr\u003E• Шум в ушах.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы\u003Cbr\u003E• Агранулоцитоз, лейкопения, нейтропения и тромбоцитопения.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003E• Повышение активности «печеночных» ферментов (аспартатаминотрансферазы (АСТ) и\u003Cbr\u003Eаланинаминотрансферазы (АЛТ), щелочной фосфатазы), развитие холестатического или смешанного гепатита, гепатоцеллюлярного поражения печени, иногда сопровождавшегося\u003Cbr\u003Eжелтухой.\u003Cbr\u003E• У пациентов, получавших лечение метронидазолом в комбинации с другими\u003Cbr\u003Eантибиотиками, наблюдались случаи развития печеночной недостаточности, потребовавшей\u003Cbr\u003Eпроведения трансплантации печени.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003E• Сыпь, зуд, приливы крови к кожным покровам, гиперемия кожи, крапивница.\u003Cbr\u003E• Пустулезная кожная сыпь.\u003Cbr\u003E• Фиксированная лекарственная сыпь.\u003Cbr\u003E• Синдром Стивенса-Джонсона, токсический эпидермальный некролиз.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003E• Возможно окрашивание мочи в коричнево-красноватый цвет, обусловленное наличием в\u003Cbr\u003Eмоче водорастворимого метаболита метронидазола.\u003Cbr\u003E• Дизурия, полиурия, цистит, недержание мочи, кандидоз.\u003Cbr\u003EОбщие расстройства\u003Cbr\u003E• Лихорадка, заложенность носа, артралгии, слабость.\u003Cbr\u003EЛабораторные и инструментальные данные\u003Cbr\u003E• Уплощение зубца Т на ЭКГ."},{"name":"Фармакологическое действие","value":"Метронидазол является производным 5-нитроимидазола. Механизм действия заключается в биохимическом восстановлении 5-нитрогруппы внутриклеточными транспортными протеинами анаэробных микроорганизмов и простейших. Восстановленная 5-нитрогруппа взаимодействует с дезоксирибонуклеиновой кислотой (ДНК) клетки микроорганизмов, ингибируя синтез их нуклеиновых кислот, что ведет к гибели бактерий.\u003Cbr\u003EАктивен в отношении Trichomonas vaginalis, Entamoeba histolytica, а также грамотрицательных анаэробов Bacteroides spp. (в т.ч. Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp. и некоторых грамположительных анаэробов (чувствительные штаммы Eubacterium spp., Clostridium spp., Peptococcus niger., Peptostreptococcus spp.). Минимальная подавляющая концентрация для этих штаммов составляет 0,125-6,25 мкг/мл.\u003Cbr\u003EВ сочетании с амоксициллином проявляет активность в отношении Helicobacter pylori (амоксициллин подавляет развитие резистентности к метронидазолу).\u003Cbr\u003EК метронидазолу не чувствительны аэробные микроорганизмы и факультативные анаэробы, но в присутствии смешанной флоры (аэробы и анаэробы) метронидазол действует синергически с антибиотиками, эффективными против обычных аэробов."},{"name":"Фармакологическая группа","value":"противомикробное и противопротозойное средство"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 6 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В оригинальной упаковке (контурная ячейковая упаковка в пачке) при температуре не выше 30 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Сообщалось о приеме внутрь разовых доз метронидазола до 12 г при суицидальных попытках и\u003Cbr\u003Eслучайных передозировках.\u003Cbr\u003EСимптомы: рвота, атаксия, небольшая дезориентация.\u003Cbr\u003EЛечение: специфического антидота при передозировке метронидазолом не существует. В случае\u003Cbr\u003Eподозрения на значительное превышение дозы следует проводить симптоматическую и\u003Cbr\u003Eподдерживающую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Поскольку метронидазол проходит через плацентарный барьер и его действие на органогенез плода человека неизвестно, применение препарата Метронидазол Реневал во время беременности противопоказано.\u003Cbr\u003EМетронидазол проникает в грудное молоко, поэтому применение препарата в период грудного вскармливания противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Учитывая риск развития таких побочных реакций, как спутанность сознания, головокружение, галлюцинации, нарушения зрения, рекомендуется во время лечения воздержаться от управления автомобилем, от занятий другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Поскольку одновременный прием метронидазола с алкоголем (этанолом) может оказывать эффект, аналогичный эффекту дисульфирама (гиперемия кожных покровов, приливы крови к кожным покровам, рвота, тахикардия), следует предупредить пациентов о том, что во время лечения и в течение хотя бы одного дня после окончания применения препарата не следует употреблять алкогольные напитки или лекарственные препараты, содержащие этанол.\u003Cbr\u003EСледует тщательно взвешивать показания для длительного приема препарата (более 10 дней) и при отсутствии строгих показаний избегать его длительного применения. Если при наличии строгих показаний (тщательно взвесив соотношение между ожидаемым эффектом и потенциальным риском возникновения осложнений), препарат применяется более длительно, чем это обычно рекомендуется, то лечение следует проводить под контролем гематологических показателей (особенно лейкоцитов) и побочных реакций, таких как периферическая или центральная нейропатия, проявляющихся парестезиями, атаксией, головокружением, судорогами, при появлении которых лечение должно быть прекращено.\u003Cbr\u003EПри лечении трихомонадного вагинита у женщин и трихомонадного уретрита у мужчин необходимо воздерживаться от половых контактов. Обязательно одновременное лечение половых партнеров. Лечение не прекращается во время менструаций. После терапии трихомониаза следует провести контрольные пробы в течение 3 очередных циклов до и после менструации.\u003Cbr\u003EСообщалось о развитии тяжелой гепатотоксичности / острой печеночной недостаточности (включая случаи с летальным исходом) у пациентов с синдромом Коккейна. Следует с\u003Cbr\u003Eосторожностью и только в случае отсутствия альтернативного лечения применять метронидазол у данной категории пациентов.\u003Cbr\u003EИсследования функции печени следует проводить в начале лечения, во время лечения и в течение 2 недель после окончания лечения.\u003Cbr\u003EПациентам с синдромом Коккейна следует рекомендовать немедленно сообщать врачу о развитии любых симптомов потенциального поражения печени (таких как впервые выявленная сохраняющаяся боль в животе, анорексия, тошнота, рвота, лихорадка, недомогание, желтуха, потемнение мочи или кожный зуд).\u003Cbr\u003EНеобходимо принимать во внимание, что метронидазол может иммобилизировать трепонемы, что приводит к ложноположительному тесту Нельсона.\u003Cbr\u003EС осторожностью\u003Cbr\u003EПеченочная энцефалопатия; острые и хронические заболевания периферической и центральной\u003Cbr\u003Eнервной системы (риск утяжеления неврологической симптоматики); почечная недостаточность."},{"name":"Взаимодействие","value":"С дисульфирамом\u003Cbr\u003EСообщалось о развитии психотических реакций у пациентов, получавших одновременно\u003Cbr\u003Eметронидазол и дисульфирам (интервал между применением этих лекарственных препаратов\u003Cbr\u003Eдолжен быть не менее 2 недель).\u003Cbr\u003EС этанолом\u003Cbr\u003EВозможно возникновение дисульфирамоподобных реакций (гиперемия кожных покровов,\u003Cbr\u003Eприливы крови к кожным покровам, рвота, тахикардия).\u003Cbr\u003EС непрямыми антикоагулянтами (варфарин)\u003Cbr\u003EУсиление антикоагулянтного эффекта и повышение риска развития кровотечения, связанного со\u003Cbr\u003Eснижением печеночного метаболизма непрямых антикоагулянтов, что может приводить к\u003Cbr\u003Eудлинению протромбинового времени. В случае одновременного применения метронидазола и\u003Cbr\u003Eнепрямых антикоагулянтов требуется более частый контроль протромбинового времени и при\u003Cbr\u003Eнеобходимости коррекция доз антикоагулянтов.\u003Cbr\u003EС препаратами лития\u003Cbr\u003EПри одновременном применении метронидазола с препаратами лития может повышаться\u003Cbr\u003Eконцентрация последнего в плазме крови. При одновременном применении следует\u003Cbr\u003Eконтролировать концентрации лития, креатинина и электролитов в плазме крови.\u003Cbr\u003EС циклоспорином\u003Cbr\u003EПри одновременном применении метронидазола с циклоспорином может повышаться\u003Cbr\u003Eконцентрация циклоспорина в плазме крови. В случае необходимости одновременного\u003Cbr\u003Eприменения метронидазола и циклоспорина следует контролировать концентрации циклоспорина\u003Cbr\u003Eи креатинина в плазме крови.\u003Cbr\u003EС циметидином\u003Cbr\u003EЦиметидин ингибирует метаболизм метронидазола, что может привести к повышению его\u003Cbr\u003Eконцентрации в плазме крови и увеличению риска развития побочных явлений.\u003Cbr\u003EС лекарственными препаратами, индуцирующими изоферменты микросомального окисления в\u003Cbr\u003Eпечени (фенобарбитал, фенитоин)\u003Cbr\u003EОдновременное применение метронидазола с лекарственными препаратами, индуцирующими\u003Cbr\u003Eизоферменты микросомального окисления в печени (фенобарбитал, фенитоин), может ускорять\u003Cbr\u003Eвыведение метронидазола, в результате чего снижается его концентрация в плазме крови.\u003Cbr\u003EС фторурацилом\u003Cbr\u003EМетронидазол уменьшает клиренс фторурацила, приводя к увеличению его токсичности.\u003Cbr\u003EС бусульфаном\u003Cbr\u003EМетронидазол повышает концентрацию бусульфана в плазме крови, что может приводить к\u003Cbr\u003Eразвитию тяжелого токсического действия бусульфана.\u003Cbr\u003EС недеполяризующими миорелаксантами (векурония бромид)\u003Cbr\u003EНе рекомендуется применять с недеполяризующими миорелаксантами (векурония бромид).\u003Cbr\u003EС сульфаниламидами\u003Cbr\u003EСульфаниламиды усиливают противомикробное действие метронидазола."},{"name":"Регистрационный номер","value":"ЛC-002069"},{"name":"Дата государственной регистрации","value":"04.03.2021"},{"name":"Владелец регистрационного удостоверения","value":"ПФК Обновление"},{"name":"Изготовитель","value":"ПФК Обновление"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Метронидазол"},{"name":"Срок годности","value":"37 мес."}]}],"transitionId":"tr_3345836971671305592"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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    Цена 161 ₽ вместо 185
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  • Метронидазол таб., 250 мг, 20 шт.
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    Метронидазол таб., 250 мг, 20 шт.

    Рейтинг товара: 4.6 из 5
    на основе 38 оценок
    Цена 44 ₽
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  • Трихопол таб., 250 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5ptofg3zz3y/toggleWishlist":{"skuId":"228092185","productId":1780859035,"offerId":"NwpM6bSZZyD867P-p9ZjsQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtsnp1r3o0boSEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIm4GX0QYQmdLhbBi53dAHIPfcwQc=","sign":"MM+NbI2UUqRbwU3Tzs9E8cGKZoYbAemM5QSG0JHNQxc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5ptofg3zz3y/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Трихопол таб., 250 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 16 оценок
    Цена 96 ₽
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  • Метронидазол таб., 250 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5fud7x34h4j/toggleWishlist":{"skuId":"101772064080","productId":661915017,"offerId":"YU3BT0Ev__WEF-IVvbGnsQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtsnp1r3o0boSEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIiYvQuwIQ0OrZkPsCGKev2Acg99zBBw==","sign":"hwBC5qzKmGm1zL0EOYyb252/CRbojkTIqSks7mPbh6A="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5fud7x34h4j/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Метронидазол таб., 250 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 18 оценок
    Цена 109 ₽
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  • Метронидазол таб., 250 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ofgag5f8edi/toggleWishlist":{"skuId":"453477103","productId":1780859129,"offerId":"HAJllFgYnmRiohWuNJnU-g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtsnp1r3o0boSEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI+YGX0QYQ74We2AEYm5eQByD33MEH","sign":"D6aEorOg30OMqxpOGQy2ynUUB+xi7m1b3AjBweZcmp0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ofgag5f8edi/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Метронидазол таб., 250 мг, 20 шт.

    Рейтинг товара: 4.7 из 5
    на основе 18 оценок
    Цена 40 ₽
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  • Амоксициллин капс., 500 мг, 16 шт.
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    Амоксициллин капс., 500 мг, 16 шт.

    Рейтинг товара: 4.9 из 5
    на основе 64 оценки
    Цена 115 ₽
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  • Азитромицин капс., 500 мг, 3 шт.
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    Азитромицин капс., 500 мг, 3 шт.

    Рейтинг товара: 4.7 из 5
    на основе 156 оценок
    Цена 96 ₽
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  • Ципрофлоксацин таб. п/о плен., 250 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ot0x7c2xwus/toggleWishlist":{"skuId":"227814594","productId":1434054466,"offerId":"ZBd_bcnTOtVxIpRDG9r60g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtsnp1r3o0boSEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIwt7nqwUQwtnQbBjX8c8GIPfcwQc=","sign":"HLnOHeZJ1vqw5QWjCyKqjNbd/XMuIvJk8y+EAWoWvpg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ot0x7c2xwus/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ципрофлоксацин таб. п/о плен., 250 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 20 оценок
    Цена 44 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ot0x7c2xwus/addToCartButton":{"offerId":"ZBd_bcnTOtVxIpRDG9r60g","skuId":"227814594","pendingCartItem":{"productId":1434054466,"offerId":"ZBd_bcnTOtVxIpRDG9r60g","showPlaceId":"OTNDnItfwRMjN9MRHuEMMjqVp0oOMitJdUewLNR64rp0Dqu0t5D79k6XCOAkR12WTFjm6DzZE7yAfgCJAZZw5zizeEVJYfBk2GlX8BFoiihJ-7Qp1YReLmeXF7oLtNKVl2Hpuvyc6wpHlmqmyf4KzmUpkkixwP6_o0DUNaCZxZqPGipMjueVySrNIxi3tp_Df9ImE6F89z0VP_YtFZzzLg,,","feeShow":"OTNDnItfwRMjN9MRHuEMMjqVp0oOMitJdUewLNR64rp0Dqu0t5D79k6XCOAkR12WTFjm6DzZE7yAfgCJAZZw5zizeEVJYfBk2GlX8BFoiihJ-7Qp1YReLmeXF7oLtNKVl2Hpuvyc6wpHlmqmyf4KzmUpkkixwP6_o0DUNaCZxZqPGipMjueVySrNIxi3tp_Df9ImE6F89z0VP_YtFZzzLg,,","skuId":"227814594","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"44","currency":"RUR"},"hid":"15756919","name":"Ципрофлоксацин таб. п/о плен., 250 мг, 10 шт.","label":"7idarwog0tt","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":3612791,"key":"img_id4603253534710895713.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCkDTJdUMBhxLcrhkF1w97S0Dq4px-uGWx_On5fPKZgdLWQfj6AAujfTC6FeIhbdL4yO8eJxozRTOnx3ZAs57HNb0IPeYvZkfaghSVxhqfv3UkpLVsWIohH7qjxSbPAKeHmUEG-ACQzP0XK0Jiz6SL0_Hd2_MLNEiRw3MrwKykGOmSguAQPJg-SpMLSPo8PdiPe0pPKnBBwDhNbR6VTyVVG96noQkCrAJjIQHdc8BWnBdTvZd2hD6P9nmB6gwvzc2KOOhW3G6uqlME_lQpV-5QWyUt3wu-YX6_669j2_vBTrz4Vq5gwWao_CuW6JRVlGlmeUoC1A6CijFUwMhVg9enDIuZx8vEIHTm1s1PB26cFqJ4mU6s8scPoWR02BGteRiqyhTjuaufMh9pGM8TRntxpAzUOWELO_T98E7Ob-YnOYG191GAT39c5UTOm52fnapHX4KDhaZv_hwBv3IRLqh4ig9evk8jPVi_NhC54HDIu1d8VIv3HEZVyKQ-AQKlxeATyoCykyUhnMSSnKK0RqJsRH5kLcwZIgZwBv7uWGq3atmXsHq8OWCO-D0B3ZGImiU6cEmvktnwhIpct4qrZSFpIVlLnMmB_Qgbddo41z-VymRlR_uXq4o_D8t_ogx2-1cgTfGI7Z9vWb1qbEFmxfODRXqhiT8BSonQbEYG2HCYP_GMCw0Caj98Fed4IFku4i3iSBQRvdjzdN2BN1YTA-G_0CoghVmXEBmWkqztqSy9l6bpM7RAYKsxIaEn4dWUObjVHNqrcvguS01d9eDjGvcH--k2v67YimK1AbWq7vZP6zXBhrebba1TqG0LIC_bcETTYZyfcXdEUIoy52Q8TEnYFrGGCnVS1LX4UBzAvsAw1IqpETUeC79Ntkg0GVFEkPnvH6UpL25GMsf0cB_D3QOdtoBpJWsHYtu9AUGHPUlfqoboThi2SXvMjhvV21hVHwrxUDhggwRHlEIjiFQ9qigGI48JiDvLVDCD-B5bDnLNV7J1irwCZcUNgb227tDLe8KWXwIIEvsbPo-0-vgdCE-GgyGc7_ZHaLPk6xsBs8o8T_A0DtgXR0XdeF4uokwsl9W0iU99xELH8e03zG8yoMLIp55hFgLJyFexUnDSnB_9YOvVhNzJbIq4Ox5cae1eIN7mHK8-jU26xlxhHoIZ8pL1PD887KGfLi8K41esQEeGes9eNYvWhKABmWkpFJCqGwyK_rEW-4uugh7POgSIIjzCwfkJRXIV7Uvdu2IIW-0lZw3h9lYP3ioJ8p2yyFY16eGyerxvMo2aya16O9pBWDLVVSQuuHL_UDZOCgA9D-5f0LayB-wua3dlkaSlVH5_dLVlHWBVPx_aYNISvUCDb2jIAuUwKlQ7yxJbWn8DlCfwNny0GlOoWB_BC0vqotrNr4eRIY-CA3OwCcMQ5hlXazOO5U10jBi58egJlTwr-uxgsJgbE_MvPwiJkAQ3TtgOMG_rFLvkmJmTkQm_obo_TEGQvFxB4m3wMFaaCAlreZXYcqZyt-PuhcOhxyoNdSfr305B5q4vPsfzteeBlfXpttSPDLv3wlSOzmsFdA-ZvSm9q15kLGQq8s4EFetFo36viOXVhspCwYMJtzk0N8nTmeQ9FrcFcbgS-0jmY_9k7XJdVCtnregSdlo5WhQLr1MQw6xw_15p37KUcwF-LbdTnxzeVG86JUzqvey5nan3ttgLgzGkIH8s5SVvfFUYh-YAcFhKdeASs2suuz5ZBFeli1IjMZ7QzDACtVPrbmSkEcMn_DzmI6ajXPvsDnwwneG_is7jwfrMnx4Zy43nu-q0rxOCAHCTkH9Ospm2nZogppxMcrYlyP3KcJeFAkoTugUU6sSREDmsEv3rOZHu2BLKGzBHHNNl_DMGNQ_v4jGBMWWRw34xoUjlKmKE9drGb76j5fHQoyyS8l1VULhjYPMPDlx8HJ1_2WZURljwrVuJbh6z3q4fm4frlNeBWvMQfzsFIy7h2DnsKvqalhnwa3jp4L7GsZr02mnv981WA_8dIMajhLjyTpAKlmvNcn3FXXxI4LLMM91rWhe4zUgFf-kA9pQ5Kpq9zYmLEmMUHIlbb88PfaxlyDz6svTHWD1WZrUFBlxE3CC1I2AJE9dyK0XUjqQLDpo_lChehuVukRlhfksq6HcORLMpbyOYDoBXVqG_ztgcpxrPZcKkdG-5-k1Ov_DBSQ5_3yg9EIKSuQ_3E_xLOZym0XMCzhckwgJmhUbBbscc5gj2rCoJ5tWdq0PHWLyJRzaB5On9DQYG7UQM5nwfzVUTD_0IHbBHqYMKmZ2_QdSyUKUPEjyxXpzKgETFGlvmBA9nKgRtGu12FJfhBCXqb1t62iB2GJrGKfLFfDDAOVgD38JU_qgnkLF21Xbak3o6MLo32AqKLxOuQOGQLcaUsZ1jKvQLHiDv3XfyEBw1knKJ8AFNrhfjHGDsDhUdcfBgxXCud1mY2tHD6F8CrwmdRIHRGvdGjmrgHXMCNj4DBcqwbn0EdbEGqLm1rA3wDjs5LcfpuQgUJS9yMvK0PP6CpLdI6uFItHP_2wZQwXS3QXbaYWDHITaLRIv_ZPjPWC5oIzU41P_0SNMnj0s4goo54K5P1PB_Lw4Ii78DJ9nQVFl7huDOvOGycioQxYXmQ1IJlEMfYlel3ynykpgJ1nPW2omqNVf3rIiV0s6KhOB78bDdjM_Yi2LUPAfjxYWWGorttvrlHKHmw8FAC-lYxq7ewcKtR0ZCmODxHfA9ZdMTfLCSBlNIapiklxYxWC9uWypkfjiuN9uTKCLVQVQvppN4marvQodPy1MFuJccFgO-WRzVIwnu-KIb-PjJXIgtMd-2IBsue5fffm2JCzR8W48rdhDet_wwWzEDLfWE5nfZBsmoUEzdUo9oo80vZotRPrdmSPO0OcWGbAWkQujbvDtD0dmsMx6wqiJ_dP0C9_kKkX7dNEo_t_DuUtpyxLuVQUGyjCY2gbGyPJ4jLb_VLl5I4NdQBxUi1nBwwF8N8HW6mVyWKK9iA1Poe6qjr-0y5g4fHwt47n0HAb_p12fpOgnjSoe/b64e=1/sign=8fe6b5baa67ffbb217e8219fb6b50ff5/keyno=MARKET_1/*","showUid":"17179763179785266541806008","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtsnp1r3o0boSEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIwt7nqwUQwtnQbBjX8c8GIPfcwQc=","sign":"HLnOHeZJ1vqw5QWjCyKqjNbd/XMuIvJk8y+EAWoWvpg="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtsnp1r3o0boSEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIwt7nqwUQwtnQbBjX8c8GIPfcwQc=","sign":"HLnOHeZJ1vqw5QWjCyKqjNbd/XMuIvJk8y+EAWoWvpg="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ot0x7c2xwus/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Левомицетин Реневал таб. п/о плен., 500 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hgr91uummdh/toggleWishlist":{"skuId":"101510541248","productId":1484171071,"offerId":"JDxIpGdwVzK8ek3qJYiIwQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtsnp1r3o0boSEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIv87awwUQwN//k/oCGPKsgggg99zBBw==","sign":"6/fluGtNl8gqIFKRwdGKnvNcT5TDqDkPEIV89NWbFUY="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hgr91uummdh/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Левомицетин Реневал таб. п/о плен., 500 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 15 оценок
    Цена 162 ₽
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  • Тетрациклин Реневал таб. п/о плен., 100 мг, 20 шт.
    –22 %
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    Тетрациклин Реневал таб. п/о плен., 100 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 180 ₽ вместо 230
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  • Азитромицин капс., 250 мг, 6 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-1z6yzr7jvou/toggleWishlist":{"skuId":"226178391","productId":1434054447,"offerId":"dbKT67w1MXmTdVGaIqWkKQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtsnp1r3o0boSEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIr97nqwUQ1+rsaxiEqbIIIPfcwQc=","sign":"PYRVyf6nXBJuo0FcIyxRsyRfYNpGknjT1xRmjoO7LaU="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-1z6yzr7jvou/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Азитромицин капс., 250 мг, 6 шт.

    Рейтинг товара: 5 из 5
    на основе 14 оценок
    Цена 94 ₽
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Инструкция

Показания к применению

• Протозойные инфекции: внекишечный амебиаз (включая амебный абсцесс печени),
кишечный амебиаз (амебная дизентерия), трихомониаз.
• Инфекции, вызываемые Bacteroides spp. (в том числе B. fragilis, B. distasonis,
B. ovatus, B. thetaiotaomicron, B. vulgatus); инфекции костей и суставов; инфекции центральной
нервной системы (ЦНС), в том числе менингит, абсцесс мозга; бактериальный эндокардит;
пневмония, эмпиема и абсцесс легких; сепсис.
• Инфекции, вызываемые Clostridium spp., Peptococcus niger, Peptostreptococcus spp.: инфекции
брюшной полости (перитонит, абсцесс печени), инфекции органов малого таза (эндометрит,
абсцесс фаллопиевых труб и яичников, инфекции свода влагалища).
• Псевдомембранозный колит, связанный с применением антибиотиков.
• Гастрит или язва двенадцатиперстной кишки, связанные с Helicobacter pylori (в составе
комплексной терапии).
• Профилактика послеоперационных осложнений (особенно после операций на ободочной
кишке, в параректальной области, аппендэктомии, гинекологических операций).

Противопоказания

Гиперчувствительность к метронидазолу, к другим производным нитроимидазола, к имидазолам
и к другим компонентам препарата; органические поражения ЦНС (в том числе эпилепсия);
лейкопения (в том числе в анамнезе); печеночная недостаточность (в случае назначения больших
доз); беременность, период лактации; детский возраст до 6 лет.

Способ применения и дозы

Метронидазол принимают внутрь, до или после еды, запивая достаточным количеством воды.
При кишечном амебиазе метронидазол применяют в суточной дозе 1500 мг (разделенной на 3
приема) в течение 7 дней.
При острой амебной дизентерии суточная доза составляет 2250 мг (разделенная на 3 приема).
Детям от 6 до 15 лет назначают суточную дозу 500 мг (разделенную на 2 приема).
При абсцессе печени и других внекишечных формах амебиаза максимальная суточная доза
составляет 2500 мг (разделенная на 3 приема) в течение 3-5 дней, в комбинации с
тетрациклиновыми антибиотиками и другими методами терапии. Детям от 6 до 15 лет назначают
суточную дозу 500 мг (разделенную на 2 приема).
При трихомониазе у женщин (уретрит и вагинит) метронидазол назначают однократно в дозе 2 г
или в виде курсового лечения по 250 мг 2 раза в сутки в течение 10 дней.
При трихомониазе у мужчин (уретрит) метронидазол назначают однократно в дозе 2 г или в
виде курсового лечения по 250 мг 2 раза в сутки в течение 10 дней.
Лечение анаэробных инфекций обычно начинают с внутривенных инфузий с последующим
переходом на таблетки. Для взрослых доза препарата составляет 500 мг 3 раза в сутки. Длительность
лечения составляет до 7 дней.
Для лечения псевдомембранозного колита метронидазол назначают по 500 мг 3-4 раза в сутки.
Длительность лечения определяется врачом.
Для эрадикации Helicobacter pylori метронидазол назначают по 500 мг 3 раза в сутки в составе
комбинированной терапии (например, с амоксициллином).
Для профилактики послеоперационных осложнений метронидазол назначают в суточной дозе
750-1500 мг (разделенной на 3 приема) за 3-4 дня до операции. Через 1-2 дня после операции
(когда уже разрешен прием внутрь) метронидазол назначают по 750 мг в сутки в течение 7 дней.
Полная инструкция
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Метронидазол Реневал таб.
Метронидазол Реневал таб., 250 мг, 24 шт.
5.0
(3)
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3 вопроса
Инструкция

131 ₽

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5.0
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У продавца:3 оценки·1 отзыв
У всех продавцов:26 оценок·18 отзывов
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4 месяца назад • slava puzanoff • Куплен на Маркете
Достоинства: действует
Недостатки: дисбактериоз , горький на вкус (очень)
Посмотреть все отзывы на Маркете
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