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Бацидерм пор. д/нар. прим. фл., 250 МЕ/г+5000 МЕ/г, 10 г

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Коротко о товаре

Артикул Маркета
4951731251
Тип препарата
Назначение
Действующее вещество
Форма выпуска
порошок для наружного применения
Инструкция
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0,00416 г) - 250 ME, неомицин (в форме неомицина сульфата* - 0,00746 г) - 5000 ME.\u003Cbr\u003EВспомогательное вещество: крахмал кукурузный-0,987 г.\u003Cbr\u003E* Количественное содержание в граммах зависит от исходной активности действующих веществ.\u003Cbr\u003EСодержание действующих веществ в граммах указано из расчета активности:\u003Cbr\u003E- 60 МЕ/мг бацитрацина в пересчете на бацитрацина цинк;\u003Cbr\u003E- 670 МЕ/мг неомицина в пересчете на неомицина сульфат."},{"name":"Действующее вещество","value":"Бацитрацин+Неомицин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["27144131:36090540"]}}},{"name":"Способ применения и дозы","value":"Наружно.\u003Cbr\u003EВозможно наносить, не касаясь пораженной поверхности руками. Порошок наносят тонким слоем на пораженные участки 2-4 раза в день взрослым и детям; если это целесообразно - под повязку. Площадь нанесения порошка не должна превышать 1% от площади поверхности тела (что соответствует размеру ладони пациента).\u003Cbr\u003EПродолжительность лечения не должна превышать 7 дней.\u003Cbr\u003EПациенты с нарушением функции печени и/или почек\u003Cbr\u003EПри применении доз, намного превышающих рекомендуемые, необходимо учитывать возможность развития нефро- и/или ототоксических изменений, из-за повышенного риска возможной абсорбции активных веществ, особенно у пациентов с нарушением функции печени и/или почек. Рекомендуется проводить соответствующие анализы мочи и крови или аудиометрические исследования.\u003Cbr\u003EПациенты пожилого возраста (65 лет и старше)\u003Cbr\u003EКоррекция дозы у пожилых пациентов не требуется."},{"name":"Побочные действия","value":"По данным Всемирной организации здравоохранения (ВОЗ) нежелательные эффекты классифицированы в соответствии с их частотой развития следующим образом: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C1/10000); частота неизвестна - по имеющимся данным установить частоту возникновения не представлялось возможным.\u003Cbr\u003EПрепарат обычно хорошо переносится при наружном применении.\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003Eредко: аллергические реакции (при наличии аллергических реакций на неомицин в анамнезе в 50% случаев возможно развитие перекрестной аллергии к другим аминогликозидам);\u003Cbr\u003Eчастота неизвестна: повышение чувствительности к различным веществам, включая неомицин (как правило, наблюдается при использовании в терапии хронических дерматозов), в некоторых случаях аллергические реакции могут выглядеть как отсутствие эффекта от проводимой терапии.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003Eчастота неизвестна: поражение вестибулярного нерва, нейромышечная блокада.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003Eчастота неизвестна: ототоксичность.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003Eредко: аллергические реакции, манифестирующие в виде контактного дерматита, аллергическая реакция на неомицин.\u003Cbr\u003Eчастота неизвестна: аллергические реакции в виде покраснения и сухости кожи, кожных высыпаний и зуда (при длительном применении).\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003Eчастота неизвестна: нефротоксичность.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или отмечаются любые другие побочные эффекты, не указанные в инструкции, следует немедленно сообщить об этом врачу."},{"name":"Фармакологическое действие","value":"Препарат является комбинированным антибактериальным препаратом, предназначенным для наружного применения.\u003Cbr\u003EПрепарат содержит два бактерицидных антибиотика: неомицин и бацитрацин, благодаря комбинации которых достигается синергизм действия.\u003Cbr\u003EБацитрацин главным образом ингибирует синтез муреина в клеточной стенке грамположительных бактерий (и некоторых грамотрицательных бактерий).\u003Cbr\u003EБацитрацин активен преимущественно против грамположительных микроорганизмов: Streptococcus hemolyticus, Staphylococcus spp., Clostridium spp., Corynebacterium diphtheriae, и некоторых грамотрицательных микроорганизмов: Neisseria spp. и Haemophilus influenzae.\u003Cbr\u003EБацитрацин также активен против Treponema pallidum, Actinomyces spp. и Fusobacteria spp.\u003Cbr\u003EРезистентность к бацитрацину встречается чрезвычайно редко.\u003Cbr\u003EЭффективность неомицина частично связана с увеличением проницаемости клеточной мембраны вследствие ингибирования синтеза белка.\u003Cbr\u003EНеомицин активен как против грамположительных, так и грамотрицательных патогенов, таких как Staphylococcus spp., Proteus spp., Enterobacter aerogenes, Klebsiella pneumoniae. Salmonella spp.. Shigella spp., Haemophilus influenzae, Pasteurella, Neisseria meningitidis, Vibrio cholerae. Bordetella pertussis, Bacillus anthracis, Corynebacterium diphtheriae, Streptococcus faecalis, Listeria monocytogenes, Escherichia coli и Mycobacterium tuberculosis. Также активен против Borrelia и Leptospira interrogans (L. icterohaemorrhagiae). Некоторые штаммы стафилококков устойчивы к неомицину.\u003Cbr\u003EБлагодаря использованию комбинации этих двух веществ достигается широкий спектр действия препарата, за исключением действия против псевдомонад, нокардий, грибов и вирусов.\u003Cbr\u003EТканевая переносимость препарата расценивается как хорошая, инактивации биологическими продуктами, кровью и тканевыми компонентами не отмечается.\u003Cbr\u003EЕсли препарат наносится на обширные участки поражения кожи (с нарушением рекомендованного режима дозирования), следует принимать во внимание возможность абсорбции препарата и ее последствия.\u003Cbr\u003EПорошок также обладает подсушивающим, успокаивающим и охлаждающим эффектом."},{"name":"Фармакологическая группа","value":"антибиотик комбинированный"},{"name":"Форма выпуска","value":"порошок для наружного применения"},{"name":"Способ применения/введения","value":"наружный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["35947170:36763741"]}}},{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25°С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При применении в дозах, существенно превышающих рекомендованные, вследствие возможного всасывания активных компонентов порошка следует обратить особое внимание на симптомы, указывающие на нефро- и/или ототоксические реакции."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата во время беременности и в период грудного вскармливания возможно только после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для плода или младенца. Следует помнить, что неомицин, как и все антибиотики аминогликозидного ряда, может проникать через плацентарный барьер. При применении системно высоких доз аминогликозидных антибиотиков было описано внутриутробное снижение слуха плода."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат не оказывает влияния на выполнение потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (в том числе управление транспортными средствами, работа с движущимися механизмами)."},{"name":"Особые указания","value":"Поскольку риск токсических эффектов возрастает при снижении функции печени и/или почек, у пациентов с печеночной и/или почечной недостаточностью следует проводить анализы крови и мочи вместе с аудиометрическим исследованием до и во время терапии препаратом.\u003Cbr\u003EПри всасывании активных компонентов препарата следует обратить особое внимание на потенциальную блокаду нейромышечной проводимости, особенно у больных с ацидозом, сопутствующей тяжелой миастенией (myasthenia gravis) или другими нейромышечными заболеваниями. При этом препараты кальция или неостигмина метилсульфат могут препятствовать развитию таких блокад.\u003Cbr\u003EПри длительном лечении должно уделяться внимание возможному росту устойчивых микроорганизмов. В таких ситуациях следует выбрать соответствующую тактику лечения. В случае применения препарата у детей, пациентов с нарушенной функцией печени и почек, а также при большой площади обрабатываемой поверхности, длительном применении и глубоких поражениях кожи рекомендуется предварительно проконсультироваться с врачом.\u003Cbr\u003EПациентам, у которых развилась аллергия или суперинфекция, препарат должен быть отменен.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EУ пациентов со снижением функции печени и/или почек, ацидозом, тяжелой миастенией или другими нейромышечными заболеваниями."},{"name":"Взаимодействие","value":"При системном всасывании активных компонентов препарата, одновременное применение цефалоспоринов или антибиотиков аминогликозидового ряда может повышать вероятность нефротоксической реакции.\u003Cbr\u003EОдновременное использование с препаратом таких диуретиков, как этакриновая кислота или фуросемид, может провоцировать ото- и нефротоксический эффект.\u003Cbr\u003EВсасывание активных компонентов препарата может усиливать явления блокады нейромышечной проводимости у больных, получающих наркотические вещества, анестетики и или миорелаксанты."},{"name":"Регистрационный номер","value":"ЛП-006253"},{"name":"Дата государственной регистрации","value":"29.12.2020"},{"name":"Владелец регистрационного удостоверения","value":"Тульская фармацевтическая фабрика","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["34324371:35649313","7893318:13877517"]}}},{"name":"Изготовитель","value":"Тульская фармацевтическая фабрика"},{"name":"Фасовщик","value":"Тульская фармацевтическая фабрика"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Срок годности","value":"360 дн."}]}},"fullSpecsGrouped":{"527627324788550768":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"кожа"},{"name":"Назначение","value":"бактериальные инфекции кожи и мягких тканей, инфицированные раны, инфицированные язвы нижних конечностей, пеленочный дерматит, профилактика инфекций после хирургических операций, трофические язвы"},{"name":"Показания к применению","value":"Порошок показан для применения при инфекциях, вызванных микроорганизмами, чувствительными к неомицину и/или бацитрацину.\u003Cbr\u003E- бактериальные инфекции кожи ограниченной распространенности, например, мокнущее контагиозное импетиго, инфицированные трофические язвы нижних конечностей, инфицированная экзема, бактериальный пеленочный дерматит, бактериальные осложнения вирусных инфекций, вызванных Herpes simplex и Herpes zoster, в т.ч. инфицирование везикул при ветряной оспе.\u003Cbr\u003E- профилактика пупочной инфекции у новорожденных.\u003Cbr\u003E- профилактика и лечение инфекции после хирургических (дерматологических) процедур: порошок может применяться для дополнительного лечения в послеоперационном периоде (после иссечения, каутеризации, эпизиотомии, лечения трещин на коже, разрыва промежности и мокнущих ран и швов)."},{"name":"Противопоказания","value":"Повышенная чувствительность к бацитрацину, неомицину, антибиотикам аминогликозидного ряда, к вспомогательным компонентам препарата;\u003Cbr\u003E- обширные поражения кожи, поскольку всасывание препарата может вызвать ототоксический эффект, сопровождающийся потерей слуха;\u003Cbr\u003E- выраженные нарушения выделительной функции вследствие сердечной или почечной недостаточности у пациентов с уже имеющимися поражениями вестибулярной и кохлеарной систем в случаях, если возможно всасывание активных компонентов препарата:\u003Cbr\u003E- инфекции наружного слухового прохода с перфорацией барабанной перепонки;\u003Cbr\u003E- применение порошка для лечения инфекций глаз;\u003Cbr\u003E- одновременное применение с аминогликозидными антибиотиками системного действия (из-за риска кумулятивной токсичности)."},{"name":"Состав","value":"На 1 г:\u003Cbr\u003EДействующие вещества: бацитрацин (в форме бацитрацина цинка* - 0,00416 г) - 250 ME, неомицин (в форме неомицина сульфата* - 0,00746 г) - 5000 ME.\u003Cbr\u003EВспомогательное вещество: крахмал кукурузный-0,987 г.\u003Cbr\u003E* Количественное содержание в граммах зависит от исходной активности действующих веществ.\u003Cbr\u003EСодержание действующих веществ в граммах указано из расчета активности:\u003Cbr\u003E- 60 МЕ/мг бацитрацина в пересчете на бацитрацина цинк;\u003Cbr\u003E- 670 МЕ/мг неомицина в пересчете на неомицина сульфат."},{"name":"Действующее вещество","value":"Бацитрацин+Неомицин"},{"name":"Способ применения и дозы","value":"Наружно.\u003Cbr\u003EВозможно наносить, не касаясь пораженной поверхности руками. Порошок наносят тонким слоем на пораженные участки 2-4 раза в день взрослым и детям; если это целесообразно - под повязку. Площадь нанесения порошка не должна превышать 1% от площади поверхности тела (что соответствует размеру ладони пациента).\u003Cbr\u003EПродолжительность лечения не должна превышать 7 дней.\u003Cbr\u003EПациенты с нарушением функции печени и/или почек\u003Cbr\u003EПри применении доз, намного превышающих рекомендуемые, необходимо учитывать возможность развития нефро- и/или ототоксических изменений, из-за повышенного риска возможной абсорбции активных веществ, особенно у пациентов с нарушением функции печени и/или почек. Рекомендуется проводить соответствующие анализы мочи и крови или аудиометрические исследования.\u003Cbr\u003EПациенты пожилого возраста (65 лет и старше)\u003Cbr\u003EКоррекция дозы у пожилых пациентов не требуется."},{"name":"Побочные действия","value":"По данным Всемирной организации здравоохранения (ВОЗ) нежелательные эффекты классифицированы в соответствии с их частотой развития следующим образом: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C1/10000); частота неизвестна - по имеющимся данным установить частоту возникновения не представлялось возможным.\u003Cbr\u003EПрепарат обычно хорошо переносится при наружном применении.\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003Eредко: аллергические реакции (при наличии аллергических реакций на неомицин в анамнезе в 50% случаев возможно развитие перекрестной аллергии к другим аминогликозидам);\u003Cbr\u003Eчастота неизвестна: повышение чувствительности к различным веществам, включая неомицин (как правило, наблюдается при использовании в терапии хронических дерматозов), в некоторых случаях аллергические реакции могут выглядеть как отсутствие эффекта от проводимой терапии.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003Eчастота неизвестна: поражение вестибулярного нерва, нейромышечная блокада.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003Eчастота неизвестна: ототоксичность.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003Eредко: аллергические реакции, манифестирующие в виде контактного дерматита, аллергическая реакция на неомицин.\u003Cbr\u003Eчастота неизвестна: аллергические реакции в виде покраснения и сухости кожи, кожных высыпаний и зуда (при длительном применении).\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003Eчастота неизвестна: нефротоксичность.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или отмечаются любые другие побочные эффекты, не указанные в инструкции, следует немедленно сообщить об этом врачу."},{"name":"Фармакологическое действие","value":"Препарат является комбинированным антибактериальным препаратом, предназначенным для наружного применения.\u003Cbr\u003EПрепарат содержит два бактерицидных антибиотика: неомицин и бацитрацин, благодаря комбинации которых достигается синергизм действия.\u003Cbr\u003EБацитрацин главным образом ингибирует синтез муреина в клеточной стенке грамположительных бактерий (и некоторых грамотрицательных бактерий).\u003Cbr\u003EБацитрацин активен преимущественно против грамположительных микроорганизмов: Streptococcus hemolyticus, Staphylococcus spp., Clostridium spp., Corynebacterium diphtheriae, и некоторых грамотрицательных микроорганизмов: Neisseria spp. и Haemophilus influenzae.\u003Cbr\u003EБацитрацин также активен против Treponema pallidum, Actinomyces spp. и Fusobacteria spp.\u003Cbr\u003EРезистентность к бацитрацину встречается чрезвычайно редко.\u003Cbr\u003EЭффективность неомицина частично связана с увеличением проницаемости клеточной мембраны вследствие ингибирования синтеза белка.\u003Cbr\u003EНеомицин активен как против грамположительных, так и грамотрицательных патогенов, таких как Staphylococcus spp., Proteus spp., Enterobacter aerogenes, Klebsiella pneumoniae. Salmonella spp.. Shigella spp., Haemophilus influenzae, Pasteurella, Neisseria meningitidis, Vibrio cholerae. Bordetella pertussis, Bacillus anthracis, Corynebacterium diphtheriae, Streptococcus faecalis, Listeria monocytogenes, Escherichia coli и Mycobacterium tuberculosis. Также активен против Borrelia и Leptospira interrogans (L. icterohaemorrhagiae). Некоторые штаммы стафилококков устойчивы к неомицину.\u003Cbr\u003EБлагодаря использованию комбинации этих двух веществ достигается широкий спектр действия препарата, за исключением действия против псевдомонад, нокардий, грибов и вирусов.\u003Cbr\u003EТканевая переносимость препарата расценивается как хорошая, инактивации биологическими продуктами, кровью и тканевыми компонентами не отмечается.\u003Cbr\u003EЕсли препарат наносится на обширные участки поражения кожи (с нарушением рекомендованного режима дозирования), следует принимать во внимание возможность абсорбции препарата и ее последствия.\u003Cbr\u003EПорошок также обладает подсушивающим, успокаивающим и охлаждающим эффектом."},{"name":"Фармакологическая группа","value":"антибиотик комбинированный"},{"name":"Форма выпуска","value":"порошок для наружного применения"},{"name":"Способ применения/введения","value":"наружный"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25°С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При применении в дозах, существенно превышающих рекомендованные, вследствие возможного всасывания активных компонентов порошка следует обратить особое внимание на симптомы, указывающие на нефро- и/или ототоксические реакции."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата во время беременности и в период грудного вскармливания возможно только после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для плода или младенца. Следует помнить, что неомицин, как и все антибиотики аминогликозидного ряда, может проникать через плацентарный барьер. При применении системно высоких доз аминогликозидных антибиотиков было описано внутриутробное снижение слуха плода."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат не оказывает влияния на выполнение потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (в том числе управление транспортными средствами, работа с движущимися механизмами)."},{"name":"Особые указания","value":"Поскольку риск токсических эффектов возрастает при снижении функции печени и/или почек, у пациентов с печеночной и/или почечной недостаточностью следует проводить анализы крови и мочи вместе с аудиометрическим исследованием до и во время терапии препаратом.\u003Cbr\u003EПри всасывании активных компонентов препарата следует обратить особое внимание на потенциальную блокаду нейромышечной проводимости, особенно у больных с ацидозом, сопутствующей тяжелой миастенией (myasthenia gravis) или другими нейромышечными заболеваниями. При этом препараты кальция или неостигмина метилсульфат могут препятствовать развитию таких блокад.\u003Cbr\u003EПри длительном лечении должно уделяться внимание возможному росту устойчивых микроорганизмов. В таких ситуациях следует выбрать соответствующую тактику лечения. В случае применения препарата у детей, пациентов с нарушенной функцией печени и почек, а также при большой площади обрабатываемой поверхности, длительном применении и глубоких поражениях кожи рекомендуется предварительно проконсультироваться с врачом.\u003Cbr\u003EПациентам, у которых развилась аллергия или суперинфекция, препарат должен быть отменен.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EУ пациентов со снижением функции печени и/или почек, ацидозом, тяжелой миастенией или другими нейромышечными заболеваниями."},{"name":"Взаимодействие","value":"При системном всасывании активных компонентов препарата, одновременное применение цефалоспоринов или антибиотиков аминогликозидового ряда может повышать вероятность нефротоксической реакции.\u003Cbr\u003EОдновременное использование с препаратом таких диуретиков, как этакриновая кислота или фуросемид, может провоцировать ото- и нефротоксический эффект.\u003Cbr\u003EВсасывание активных компонентов препарата может усиливать явления блокады нейромышечной проводимости у больных, получающих наркотические вещества, анестетики и или миорелаксанты."},{"name":"Регистрационный номер","value":"ЛП-006253"},{"name":"Дата государственной регистрации","value":"29.12.2020"},{"name":"Владелец регистрационного удостоверения","value":"Тульская фармацевтическая фабрика"},{"name":"Изготовитель","value":"Тульская фармацевтическая фабрика"},{"name":"Фасовщик","value":"Тульская фармацевтическая фабрика"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Срок годности","value":"360 дн."}]}],"transitionId":"tr_2584858958110886668"}}}}
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Инструкция

Показания к применению

Порошок показан для применения при инфекциях, вызванных микроорганизмами, чувствительными к неомицину и/или бацитрацину.
- бактериальные инфекции кожи ограниченной распространенности, например, мокнущее контагиозное импетиго, инфицированные трофические язвы нижних конечностей, инфицированная экзема, бактериальный пеленочный дерматит, бактериальные осложнения вирусных инфекций, вызванных Herpes simplex и Herpes zoster, в т.ч. инфицирование везикул при ветряной оспе.
- профилактика пупочной инфекции у новорожденных.
- профилактика и лечение инфекции после хирургических (дерматологических) процедур: порошок может применяться для дополнительного лечения в послеоперационном периоде (после иссечения, каутеризации, эпизиотомии, лечения трещин на коже, разрыва промежности и мокнущих ран и швов).

Противопоказания

Повышенная чувствительность к бацитрацину, неомицину, антибиотикам аминогликозидного ряда, к вспомогательным компонентам препарата;
- обширные поражения кожи, поскольку всасывание препарата может вызвать ототоксический эффект, сопровождающийся потерей слуха;
- выраженные нарушения выделительной функции вследствие сердечной или почечной недостаточности у пациентов с уже имеющимися поражениями вестибулярной и кохлеарной систем в случаях, если возможно всасывание активных компонентов препарата:
- инфекции наружного слухового прохода с перфорацией барабанной перепонки;
- применение порошка для лечения инфекций глаз;
- одновременное применение с аминогликозидными антибиотиками системного действия (из-за риска кумулятивной токсичности).

Способ применения и дозы

Наружно.
Возможно наносить, не касаясь пораженной поверхности руками. Порошок наносят тонким слоем на пораженные участки 2-4 раза в день взрослым и детям; если это целесообразно - под повязку. Площадь нанесения порошка не должна превышать 1% от площади поверхности тела (что соответствует размеру ладони пациента).
Продолжительность лечения не должна превышать 7 дней.
Пациенты с нарушением функции печени и/или почек
При применении доз, намного превышающих рекомендуемые, необходимо учитывать возможность развития нефро- и/или ототоксических изменений, из-за повышенного риска возможной абсорбции активных веществ, особенно у пациентов с нарушением функции печени и/или почек. Рекомендуется проводить соответствующие анализы мочи и крови или аудиометрические исследования.
Пациенты пожилого возраста (65 лет и старше)
Коррекция дозы у пожилых пациентов не требуется.
Полная инструкция
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Бацидерм пор. д/нар. прим. фл.
Бацидерм пор. д/нар. прим. фл., 250 МЕ/г+5000 МЕ/г, 10 г
5.0
(1)
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