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Описание

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Гроприносин таб., 500 мг, 20 шт.

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5.0
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Количество штук в упаковке, шт.: 20

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Коротко о товаре

Артикул Маркета
3123137300
Тип препарата
Назначение
Действующее вещество
Возраст
от 3 лет
Инструкция
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подагра;\u003Cbr\u003E- мочекаменная болезнь;\u003Cbr\u003E- хроническая почечная недостаточность;\u003Cbr\u003E- детский возраст до 3 лет (масса тела до 15-20 кг);\u003Cbr\u003E- аритмии;\u003Cbr\u003E- беременность и период грудного вскармливания."},{"name":"Состав","value":"1 таблетка содержит:\u003Cbr\u003EДействующее вещество: инозин пранобекс 500 мг.\u003Cbr\u003EВспомогательные вещества: крахмал картофельный, повидон К 25, магния стеарат."},{"name":"Действующее вещество","value":"Инозин Пранобекс","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["27144131:28710302"]}}},{"name":"Способ применения и дозы","value":"Таблетки принимают внутрь, после еды, запивая небольшим количеством воды. Препарат принимают через равные промежутки времени (8 или 6 часов) 3-4 раза в сутки.\u003Cbr\u003EРекомендованные дозы и схемы применения:\u003Cbr\u003EВзрослые: от 6 до 8 таблеток в сутки, разделенных на 3-4 приема.\u003Cbr\u003EДети от 3 лет и старше (масса тела свыше 15-20 кг): 50 мг/кг массы тела (по 1/2 таблетки на 5 кг массы тела) в сутки, разделенных на 3-4 приема.\u003Cbr\u003EКак у взрослых, так и у детей, при тяжелых инфекционных заболеваниях доза может быть увеличена индивидуально до 100 мг/кг массы тела в сутки, разделенных на 4-6 приемов. Максимальная суточная доза у взрослых составляет 3-4 г в сутки, максимальная суточная доза у детей в возрасте от 3 лет и старше - 50 мг/кг в сутки.\u003Cbr\u003EПродолжительность лечения\u003Cbr\u003EПри острых заболеваниях: лечение обычно продолжается от 5 до 14 дней. После исчезновения симптомов лечение следует продолжить в течение 1-2 дней или более, в зависимости от показаний. При необходимости, длительность лечения может быть увеличена индивидуально под контролем врача.\u003Cbr\u003EПри хронических рецидивирующих заболеваниях: лечение у взрослых и детей проводится курсами продолжительностью 5-10 дней с интервалами 8 дней. Длительность поддерживающего лечения может составить до 30 дней, при этом доза может быть снижена до 500-1000 мг/сут.\u003Cbr\u003EГерпетические инфекцию, лечение продолжается в течение 5-10 дней до исчезновения симптомов. Для уменьшения числа рецидивов в бессимптомный период препарат назначают по 500 мг 2 раза в день на протяжении 30 дней.\u003Cbr\u003EПапилломавирусные инфекции: в качестве монотерапии препарат назначается на протяжении 14-28 дней взрослым в дозе 1000 мг 3 раза в сутки, детям - 250 мг (1/2 таблетки) на 5 кг массы тела 3-4 раза в сутки.\u003Cbr\u003EРецидивирующие остроконечные кондиломы: в качестве монотерапии или в комбинации с хирургическим лечением препарат назначается взрослым в дозе 1000 мг 3 раза в сутки, детям - в дозе 250 мг на 5 кг массы тела в 3-4 приема. Проводят 3 курса по 14-28 дней с интервалом 1 месяц.\u003Cbr\u003EДисплазия шейки матки, ассоциированная с папилломавирусом человека: 2-3 курса по 1000 мг 3 раза в сутки в течение 10 дней с интервалом 10-14 дней.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EПрименение у пожилых пациентов (старше 65 лет)\u003Cbr\u003EНеобходимости в коррекции дозы нет, препарат применяется так же, как у пациентов среднего возраста. Следует учитывать, что у пожилых пациентов чаще происходит повышение концентрации мочевой кислоты в сыворотке крови и в моче, чем у пациентов среднего возраста.\u003Cbr\u003EПрименение у пациентов с почечной и печеночной недостаточностью\u003Cbr\u003EНа фоне лечения препаратом Гроприносин® следует каждые 2 недели проводить контроль содержания мочевой кислоты в сыворотке крови и в моче. Контроль активности печеночных ферментов рекомендуется проводить каждые 4 недели при длительных курсах лечения препаратом."},{"name":"Побочные действия","value":"Частота развития нежелательных реакций после применения препарата классифицирована согласно рекомендациям ВОЗ: очень частые - \u003E10%; частые - \u003E1% и \u003C10%; нечастые - \u003E0,1% и \u003C1% и частота неизвестна (невозможно определить на основании имеющихся данных).\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003EНечасто: ангионевротический отек, крапивница;\u003Cbr\u003EЧастота неизвестна: реакции гиперчувствительности, анафилактические реакции, анафилактический шок.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EЧасто: головная боль, головокружение, утомляемость, плохое самочувствие, слабость;\u003Cbr\u003EНечасто: нервозность, сонливость, бессонница.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003EЧасто: снижение аппетита, тошнота, рвота, боль в эпигастрии;\u003Cbr\u003EНечасто: диарея, запор.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003EЧасто: временное повышение активности трансаминаз и щелочной фосфатазы в плазме крови.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EЧасто: зуд, сыпь;\u003Cbr\u003EНечасто: макулопапулезная сыпь;\u003Cbr\u003EЧастота неизвестна: эритема.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003EНечасто: полиурия.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EЧасто: боль в суставах, обострение подагры.\u003Cbr\u003EЛабораторные и инструментальные данные\u003Cbr\u003EОчень часто: повышение концентрации мочевины в плазме крови, повышение концентрации мочевины в моче;\u003Cbr\u003EЧасто: повышение концентрации азота мочевины крови.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили любые другие нежелательные реакции, не указанные в инструкции, сообщите об этом лечащему врачу."},{"name":"Фармакологическое действие","value":"Инозин пранобекс - синтетическое производное пурина, представляет собой комплекс, содержащий инозин и N,N-диметиламино-2-пропанол в молярном соотношении 1:3. Обладает иммуностимулирующей активностью и неспецифическим противовирусным действием. Эффективность комплекса определяется присутствием инозина, второй компонент повышает его доступность для лимфоцитов.\u003Cbr\u003EВосстанавливает функции лимфоцитов в условиях иммунодепрессии, повышает бластогенез в популяции моноцитов, стимулирует экспрессию мембранных рецепторов на поверхности Т-хелперов, предупреждает снижение активности лимфоцитов под влиянием глюкокортикостероидов, нормализует включение в них тимидина. Инозин пранобекс стимулирует активность Т-лимфоцитов и естественных киллеров, функции Т-супрессоров и Т-хелперов, повышает продукцию иммуноглобулина G (Ig G), интерферона-гамма, интерлейкинов ИЛ-1 и ИЛ-2, снижает образование противовоспалительных цитокинов - ИЛ-4 и ИЛ-10, потенцирует хемотаксис нейтрофилов, моноцитов и макрофагов.\u003Cbr\u003EПрепарат проявляет противовирусную активность in vivo в отношении вируса простого герпеса, цитомегаловируса, вируса кори, вируса Т-клеточной лимфомы человека (тип III), полиовирусов, вирусов гриппа А и В, ЕСНО-вируса (энтероцитопатогенного вируса человека), вирусов энцефаломиокардита и конского энцефалита. Механизм противовирусного действия инозина пранобекса связан с ингибированием вирусной РНК и дигидроптероатсинтетазы, участвующей в репликации некоторых вирусов, усиливает подавленный вирусами синтез мРНК лимфоцитов, что сопровождается уменьшением синтеза вирусной РНК и трансляции вирусных белков, повышает продукцию лимфоцитами обладающих противовирусными свойствами альфа и гамма интерферонов. При комбинированном назначении усиливает действие интерферона-альфа, ацикловира и зидовудина."},{"name":"Фармакологическая группа","value":"иммуностимулирующее средство"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 3 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °C.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"При передозировке показано промывание желудка и симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Гроприносин во время беременности и в период грудного вскармливания противопоказано, так как безопасность применения не установлена."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние инозина пранобекса на психомоторные функции организма и способность управлять транспортными средствами и движущимися механизмами не исследовалось. При применении препарата следует учитывать возможность возникновения головокружения и сонливости."},{"name":"Особые указания","value":"Инозин пранобекс, как и другие противовирусные средства, наиболее эффективен при острых вирусных инфекциях, если лечение начато на ранней стадии болезни (лучше с первых суток).\u003Cbr\u003EПосле двух недель применения препарата следует провести контроль концентрации мочевой кислоты в сыворотке крови и моче.\u003Cbr\u003EПри длительном приеме (после четырех недель применения) целесообразно каждый месяц проводить контроль функции печени и почек (активность трансаминаз, уровень креатинина, мочевой кислоты в сыворотке крови).\u003Cbr\u003EПациенты со значительно повышенной концентрацией мочевой кислоты в организме могут одновременно принимать препараты, понижающие ее концентрацию. На фоне лечения необходимо контролировать концентрацию мочевой кислоты в сыворотке крови при назначении препарата одновременно с препаратами, увеличивающими концентрацию мочевой кислоты или препаратами, нарушающими функцию почек.\u003Cbr\u003EИнозин пранобекс следует с осторожностью применять у пациентов с острой печеночной недостаточностью, поскольку препарат подвергается метаболизму в печени.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EСледует соблюдать осторожность при одновременном назначении с ингибиторами ксантиноксидазы, диуретиками, зидовудином, при острой печеночной недостаточности."},{"name":"Взаимодействие","value":"Иммунодепрессанты ослабляют иммуностимулирующий эффект инозина пранобекса.\u003Cbr\u003EИнозин пранобекс следует применять с осторожностью пациентам, принимающим одновременно ингибиторы ксантиноксидазы (аллопуринол) или препараты, способные блокировать канальцевую секрецию мочевой кислоты, например, \"петлевые\" диуретики (фуросемид, торасемид, этакриновая кислота), так как это может приводить к повышению концентрации мочевой кислоты в сыворотке крови.\u003Cbr\u003EСовместное применение инозина пранобекса с зидовудином приводит к увеличению концентрации зидовудина в плазме крови и удлиняет его период полувыведения. Таким образом, при совместном применении инозина пранобекса с зидовудином может потребоваться коррекция дозы зидовудина."},{"name":"Регистрационный номер","value":"ЛП-№(000277)-(РГ-RU)\nП N005951/01"},{"name":"Дата государственной регистрации","value":"14.03.2023\n17.10.2019"},{"name":"Владелец регистрационного удостоверения","value":"Гедеон Рихтер ОАО","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["34324371:35649313","7893318:17672958"]}}},{"name":"Изготовитель","value":"Гедеон Рихтер"},{"name":"Фасовщик","value":"Гедеон Рихтер"},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Польша"},{"name":"Название препарата","value":"Гроприносин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["17796364:17992145"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"7831776159211327907":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"иммунная система"},{"name":"Назначение","value":"ОРВИ, ветряная оспа, генитальный герпес, герпес, инфекционный мононуклеоз, кератит, контагиозный моллюск, корь, лечение гриппа, лечение инфекций, вызванных вирусом простого герпеса (ВПГ), опоясывающий герпес (лишай), папилломавирусная инфекция, подострый склерозирующий панэнцефалит, профилактика гриппа, профилактика инфекций, вызванных цитомегаловирусом (ЦМВ), цитомегаловирусная инфекция"},{"name":"Показания к применению","value":"- грипп и острые респираторные вирусные инфекции;\u003Cbr\u003E- инфекции, вызванные вирусом простого герпеса 1, 2, 3 и 4 типов: генитальный и лабиальный герпес, герпетический кератит, опоясывающий лишай, ветряная оспа, инфекционный мононуклеоз, вызванный вирусом Эпштейна-Барр;\u003Cbr\u003E- цитомегаловирусная инфекция;\u003Cbr\u003E- корь тяжелого течения;\u003Cbr\u003E- папилломавирусная инфекция: папилломы гортани и голосовых связок (фиброзного типа), генитальные папилломавирусные инфекции у мужчин и женщин, бородавки;\u003Cbr\u003E- подострый склерозирующий панэнцефалит;\u003Cbr\u003E- контагиозный моллюск.\u003Cbr\u003E"},{"name":"Противопоказания","value":"- повышенная чувствительность к инозину пранобексу и другим компонентам препарата;\u003Cbr\u003E - подагра;\u003Cbr\u003E- мочекаменная болезнь;\u003Cbr\u003E- хроническая почечная недостаточность;\u003Cbr\u003E- детский возраст до 3 лет (масса тела до 15-20 кг);\u003Cbr\u003E- аритмии;\u003Cbr\u003E- беременность и период грудного вскармливания."},{"name":"Состав","value":"1 таблетка содержит:\u003Cbr\u003EДействующее вещество: инозин пранобекс 500 мг.\u003Cbr\u003EВспомогательные вещества: крахмал картофельный, повидон К 25, магния стеарат."},{"name":"Действующее вещество","value":"Инозин Пранобекс"},{"name":"Способ применения и дозы","value":"Таблетки принимают внутрь, после еды, запивая небольшим количеством воды. Препарат принимают через равные промежутки времени (8 или 6 часов) 3-4 раза в сутки.\u003Cbr\u003EРекомендованные дозы и схемы применения:\u003Cbr\u003EВзрослые: от 6 до 8 таблеток в сутки, разделенных на 3-4 приема.\u003Cbr\u003EДети от 3 лет и старше (масса тела свыше 15-20 кг): 50 мг/кг массы тела (по 1/2 таблетки на 5 кг массы тела) в сутки, разделенных на 3-4 приема.\u003Cbr\u003EКак у взрослых, так и у детей, при тяжелых инфекционных заболеваниях доза может быть увеличена индивидуально до 100 мг/кг массы тела в сутки, разделенных на 4-6 приемов. Максимальная суточная доза у взрослых составляет 3-4 г в сутки, максимальная суточная доза у детей в возрасте от 3 лет и старше - 50 мг/кг в сутки.\u003Cbr\u003EПродолжительность лечения\u003Cbr\u003EПри острых заболеваниях: лечение обычно продолжается от 5 до 14 дней. После исчезновения симптомов лечение следует продолжить в течение 1-2 дней или более, в зависимости от показаний. При необходимости, длительность лечения может быть увеличена индивидуально под контролем врача.\u003Cbr\u003EПри хронических рецидивирующих заболеваниях: лечение у взрослых и детей проводится курсами продолжительностью 5-10 дней с интервалами 8 дней. Длительность поддерживающего лечения может составить до 30 дней, при этом доза может быть снижена до 500-1000 мг/сут.\u003Cbr\u003EГерпетические инфекцию, лечение продолжается в течение 5-10 дней до исчезновения симптомов. Для уменьшения числа рецидивов в бессимптомный период препарат назначают по 500 мг 2 раза в день на протяжении 30 дней.\u003Cbr\u003EПапилломавирусные инфекции: в качестве монотерапии препарат назначается на протяжении 14-28 дней взрослым в дозе 1000 мг 3 раза в сутки, детям - 250 мг (1/2 таблетки) на 5 кг массы тела 3-4 раза в сутки.\u003Cbr\u003EРецидивирующие остроконечные кондиломы: в качестве монотерапии или в комбинации с хирургическим лечением препарат назначается взрослым в дозе 1000 мг 3 раза в сутки, детям - в дозе 250 мг на 5 кг массы тела в 3-4 приема. Проводят 3 курса по 14-28 дней с интервалом 1 месяц.\u003Cbr\u003EДисплазия шейки матки, ассоциированная с папилломавирусом человека: 2-3 курса по 1000 мг 3 раза в сутки в течение 10 дней с интервалом 10-14 дней.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EПрименение у пожилых пациентов (старше 65 лет)\u003Cbr\u003EНеобходимости в коррекции дозы нет, препарат применяется так же, как у пациентов среднего возраста. Следует учитывать, что у пожилых пациентов чаще происходит повышение концентрации мочевой кислоты в сыворотке крови и в моче, чем у пациентов среднего возраста.\u003Cbr\u003EПрименение у пациентов с почечной и печеночной недостаточностью\u003Cbr\u003EНа фоне лечения препаратом Гроприносин® следует каждые 2 недели проводить контроль содержания мочевой кислоты в сыворотке крови и в моче. Контроль активности печеночных ферментов рекомендуется проводить каждые 4 недели при длительных курсах лечения препаратом."},{"name":"Побочные действия","value":"Частота развития нежелательных реакций после применения препарата классифицирована согласно рекомендациям ВОЗ: очень частые - \u003E10%; частые - \u003E1% и \u003C10%; нечастые - \u003E0,1% и \u003C1% и частота неизвестна (невозможно определить на основании имеющихся данных).\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003EНечасто: ангионевротический отек, крапивница;\u003Cbr\u003EЧастота неизвестна: реакции гиперчувствительности, анафилактические реакции, анафилактический шок.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EЧасто: головная боль, головокружение, утомляемость, плохое самочувствие, слабость;\u003Cbr\u003EНечасто: нервозность, сонливость, бессонница.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003EЧасто: снижение аппетита, тошнота, рвота, боль в эпигастрии;\u003Cbr\u003EНечасто: диарея, запор.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003EЧасто: временное повышение активности трансаминаз и щелочной фосфатазы в плазме крови.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EЧасто: зуд, сыпь;\u003Cbr\u003EНечасто: макулопапулезная сыпь;\u003Cbr\u003EЧастота неизвестна: эритема.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003EНечасто: полиурия.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EЧасто: боль в суставах, обострение подагры.\u003Cbr\u003EЛабораторные и инструментальные данные\u003Cbr\u003EОчень часто: повышение концентрации мочевины в плазме крови, повышение концентрации мочевины в моче;\u003Cbr\u003EЧасто: повышение концентрации азота мочевины крови.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили любые другие нежелательные реакции, не указанные в инструкции, сообщите об этом лечащему врачу."},{"name":"Фармакологическое действие","value":"Инозин пранобекс - синтетическое производное пурина, представляет собой комплекс, содержащий инозин и N,N-диметиламино-2-пропанол в молярном соотношении 1:3. Обладает иммуностимулирующей активностью и неспецифическим противовирусным действием. Эффективность комплекса определяется присутствием инозина, второй компонент повышает его доступность для лимфоцитов.\u003Cbr\u003EВосстанавливает функции лимфоцитов в условиях иммунодепрессии, повышает бластогенез в популяции моноцитов, стимулирует экспрессию мембранных рецепторов на поверхности Т-хелперов, предупреждает снижение активности лимфоцитов под влиянием глюкокортикостероидов, нормализует включение в них тимидина. Инозин пранобекс стимулирует активность Т-лимфоцитов и естественных киллеров, функции Т-супрессоров и Т-хелперов, повышает продукцию иммуноглобулина G (Ig G), интерферона-гамма, интерлейкинов ИЛ-1 и ИЛ-2, снижает образование противовоспалительных цитокинов - ИЛ-4 и ИЛ-10, потенцирует хемотаксис нейтрофилов, моноцитов и макрофагов.\u003Cbr\u003EПрепарат проявляет противовирусную активность in vivo в отношении вируса простого герпеса, цитомегаловируса, вируса кори, вируса Т-клеточной лимфомы человека (тип III), полиовирусов, вирусов гриппа А и В, ЕСНО-вируса (энтероцитопатогенного вируса человека), вирусов энцефаломиокардита и конского энцефалита. Механизм противовирусного действия инозина пранобекса связан с ингибированием вирусной РНК и дигидроптероатсинтетазы, участвующей в репликации некоторых вирусов, усиливает подавленный вирусами синтез мРНК лимфоцитов, что сопровождается уменьшением синтеза вирусной РНК и трансляции вирусных белков, повышает продукцию лимфоцитами обладающих противовирусными свойствами альфа и гамма интерферонов. При комбинированном назначении усиливает действие интерферона-альфа, ацикловира и зидовудина."},{"name":"Фармакологическая группа","value":"иммуностимулирующее средство"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 3 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °C.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"При передозировке показано промывание желудка и симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Гроприносин во время беременности и в период грудного вскармливания противопоказано, так как безопасность применения не установлена."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние инозина пранобекса на психомоторные функции организма и способность управлять транспортными средствами и движущимися механизмами не исследовалось. При применении препарата следует учитывать возможность возникновения головокружения и сонливости."},{"name":"Особые указания","value":"Инозин пранобекс, как и другие противовирусные средства, наиболее эффективен при острых вирусных инфекциях, если лечение начато на ранней стадии болезни (лучше с первых суток).\u003Cbr\u003EПосле двух недель применения препарата следует провести контроль концентрации мочевой кислоты в сыворотке крови и моче.\u003Cbr\u003EПри длительном приеме (после четырех недель применения) целесообразно каждый месяц проводить контроль функции печени и почек (активность трансаминаз, уровень креатинина, мочевой кислоты в сыворотке крови).\u003Cbr\u003EПациенты со значительно повышенной концентрацией мочевой кислоты в организме могут одновременно принимать препараты, понижающие ее концентрацию. На фоне лечения необходимо контролировать концентрацию мочевой кислоты в сыворотке крови при назначении препарата одновременно с препаратами, увеличивающими концентрацию мочевой кислоты или препаратами, нарушающими функцию почек.\u003Cbr\u003EИнозин пранобекс следует с осторожностью применять у пациентов с острой печеночной недостаточностью, поскольку препарат подвергается метаболизму в печени.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EСледует соблюдать осторожность при одновременном назначении с ингибиторами ксантиноксидазы, диуретиками, зидовудином, при острой печеночной недостаточности."},{"name":"Взаимодействие","value":"Иммунодепрессанты ослабляют иммуностимулирующий эффект инозина пранобекса.\u003Cbr\u003EИнозин пранобекс следует применять с осторожностью пациентам, принимающим одновременно ингибиторы ксантиноксидазы (аллопуринол) или препараты, способные блокировать канальцевую секрецию мочевой кислоты, например, \"петлевые\" диуретики (фуросемид, торасемид, этакриновая кислота), так как это может приводить к повышению концентрации мочевой кислоты в сыворотке крови.\u003Cbr\u003EСовместное применение инозина пранобекса с зидовудином приводит к увеличению концентрации зидовудина в плазме крови и удлиняет его период полувыведения. Таким образом, при совместном применении инозина пранобекса с зидовудином может потребоваться коррекция дозы зидовудина."},{"name":"Регистрационный номер","value":"ЛП-№(000277)-(РГ-RU)\nП N005951/01"},{"name":"Дата государственной регистрации","value":"14.03.2023\n17.10.2019"},{"name":"Владелец регистрационного удостоверения","value":"Гедеон Рихтер ОАО"},{"name":"Изготовитель","value":"Гедеон Рихтер"},{"name":"Фасовщик","value":"Гедеон Рихтер"},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Польша"},{"name":"Название препарата","value":"Гроприносин"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_2022317026562000035"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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780 ₽

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  • Инозин Пранобекс таб., 500 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5jmzu4pvxrp/toggleWishlist":{"skuId":"101627150589","productId":766625082,"offerId":"u6X4kwiE5hf88gZ915fefA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ5YDjq+e4jvl/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIuorH7QIQ/YHNy/oCGISpsgggxdjBBw==","sign":"pAl5jPsmBfMo5tDDhbC9AsHdNxfore2UNRv62/H69Mo="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5jmzu4pvxrp/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Инозин Пранобекс таб., 500 мг, 20 шт.

    Рейтинг товара: 4.7 из 5
    на основе 25 оценок
    Цена 694 ₽
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  • Нормомед таб., 500 мг, 20 шт.
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    Нормомед таб., 500 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 55 оценок
    Цена 968 ₽
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  • Гроприносин-Рихтер сироп фл., 50 мг/мл, 150 мл
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    Гроприносин-Рихтер сироп фл., 50 мг/мл, 150 мл

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 720 ₽
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  • Изопринозин таб., 500 мг, 30 шт.
    –21 %
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    Изопринозин таб., 500 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 8 оценок
    Цена 1 418 ₽ вместо 1 795
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  • Валвир таб. п/о плен., 500 мг, 10 шт.
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    Валвир таб. п/о плен., 500 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    Цена 1 249 ₽
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  • Валацикловир-Фармстандарт таб. п/о плен., 500 мг, 40 шт.
    –9 %
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    Валацикловир-Фармстандарт таб. п/о плен., 500 мг, 40 шт.

    Цена 2 086 ₽ вместо 2 295
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  • Валацикловир Канон таб. п/о плен., 500 мг, 10 шт.
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    Валацикловир Канон таб. п/о плен., 500 мг, 10 шт.

    Рейтинг товара: 4.8 из 5
    на основе 73 оценки
    Цена 410 ₽
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  • Нормомед сироп фл. (в компл. с мерным колпачком), 50 мг/мл, 120 мл
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-q8wehaocysn/toggleWishlist":{"skuId":"101285935762","productId":228060838,"offerId":"OacMfpBdwUtviDcyFvxCxQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ5YDjq+e4jvl/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIpt3fbBCS9fKo+QIYoYP6BSDF2MEH","sign":"6ZYPD/i0cuXdPOXGTzDPDxmhiedsBeplNQqMU3pdSAc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-q8wehaocysn/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нормомед сироп фл. (в компл. с мерным колпачком), 50 мг/мл, 120 мл

    Рейтинг товара: 4.9 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 898 ₽ вместо 907
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  • Тилорон-СЗ таб. п/о плен., 125 мг, 10 шт.
    –1 %
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    Тилорон-СЗ таб. п/о плен., 125 мг, 10 шт.

    Рейтинг товара: 4.8 из 5
    на основе 111 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 367 ₽ вместо 371
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  • Панавир р-р для в/в введ. амп., 0.04 мг/мл, 5 мл, 2 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mpk20glmkhd/toggleWishlist":{"skuId":"101291128738","productId":228054938,"offerId":"6DEob71be2q1S1hXu6j12A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ5YDjq+e4jvl/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYImq/fbBCi76+r+QIY+tzQByDF2MEH","sign":"q2pBrgLNLWqwU0SSCPbc9Wh9oZ0K7KwDFarUnTnR4us="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mpk20glmkhd/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Панавир р-р для в/в введ. амп., 0.04 мг/мл, 5 мл, 2 шт.

    Рейтинг товара: 4.7 из 5
    на основе 12 оценок
    Цена 1 799 ₽
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  • Валацикловир таб. п/о плен., 500 мг, 10 шт.
    –6 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ls6x2f0m9f7/toggleWishlist":{"skuId":"101819027055","productId":1770186437,"offerId":"QxYNslJC8aPgD8S80bGrfA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ5YDjq+e4jvl/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIxc2LzAYQ75yMp/sCGKOi2QcgxdjBBw==","sign":"0Vvx4Nz6Bh0C3XLrdM2KqqS0Jd6hMK/lxg9YhVhqFAc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ls6x2f0m9f7/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Валацикловир таб. п/о плен., 500 мг, 10 шт.

    Рейтинг товара: 4.9 из 5
    на основе 36 оценок
    Цена 340 ₽ вместо 361
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Инструкция

Показания к применению

- грипп и острые респираторные вирусные инфекции;
- инфекции, вызванные вирусом простого герпеса 1, 2, 3 и 4 типов: генитальный и лабиальный герпес, герпетический кератит, опоясывающий лишай, ветряная оспа, инфекционный мононуклеоз, вызванный вирусом Эпштейна-Барр;
- цитомегаловирусная инфекция;
- корь тяжелого течения;
- папилломавирусная инфекция: папилломы гортани и голосовых связок (фиброзного типа), генитальные папилломавирусные инфекции у мужчин и женщин, бородавки;
- подострый склерозирующий панэнцефалит;
- контагиозный моллюск.

Противопоказания

- повышенная чувствительность к инозину пранобексу и другим компонентам препарата;
- подагра;
- мочекаменная болезнь;
- хроническая почечная недостаточность;
- детский возраст до 3 лет (масса тела до 15-20 кг);
- аритмии;
- беременность и период грудного вскармливания.

Способ применения и дозы

Таблетки принимают внутрь, после еды, запивая небольшим количеством воды. Препарат принимают через равные промежутки времени (8 или 6 часов) 3-4 раза в сутки.
Рекомендованные дозы и схемы применения:
Взрослые: от 6 до 8 таблеток в сутки, разделенных на 3-4 приема.
Дети от 3 лет и старше (масса тела свыше 15-20 кг): 50 мг/кг массы тела (по 1/2 таблетки на 5 кг массы тела) в сутки, разделенных на 3-4 приема.
Как у взрослых, так и у детей, при тяжелых инфекционных заболеваниях доза может быть увеличена индивидуально до 100 мг/кг массы тела в сутки, разделенных на 4-6 приемов. Максимальная суточная доза у взрослых составляет 3-4 г в сутки, максимальная суточная доза у детей в возрасте от 3 лет и старше - 50 мг/кг в сутки.
Продолжительность лечения
При острых заболеваниях: лечение обычно продолжается от 5 до 14 дней. После исчезновения симптомов лечение следует продолжить в течение 1-2 дней или более, в зависимости от показаний. При необходимости, длительность лечения может быть увеличена индивидуально под контролем врача.
При хронических рецидивирующих заболеваниях: лечение у взрослых и детей проводится курсами продолжительностью 5-10 дней с интервалами 8 дней. Длительность поддерживающего лечения может составить до 30 дней, при этом доза может быть снижена до 500-1000 мг/сут.
Герпетические инфекцию, лечение продолжается в течение 5-10 дней до исчезновения симптомов. Для уменьшения числа рецидивов в бессимптомный период препарат назначают по 500 мг 2 раза в день на протяжении 30 дней.
Папилломавирусные инфекции: в качестве монотерапии препарат назначается на протяжении 14-28 дней взрослым в дозе 1000 мг 3 раза в сутки, детям - 250 мг (1/2 таблетки) на 5 кг массы тела 3-4 раза в сутки.
Рецидивирующие остроконечные кондиломы: в качестве монотерапии или в комбинации с хирургическим лечением препарат назначается взрослым в дозе 1000 мг 3 раза в сутки, детям - в дозе 250 мг на 5 кг массы тела в 3-4 приема. Проводят 3 курса по 14-28 дней с интервалом 1 месяц.
Дисплазия шейки матки, ассоциированная с папилломавирусом человека: 2-3 курса по 1000 мг 3 раза в сутки в течение 10 дней с интервалом 10-14 дней.
Особые группы пациентов
Применение у пожилых пациентов (старше 65 лет)
Необходимости в коррекции дозы нет, препарат применяется так же, как у пациентов среднего возраста. Следует учитывать, что у пожилых пациентов чаще происходит повышение концентрации мочевой кислоты в сыворотке крови и в моче, чем у пациентов среднего возраста.
Применение у пациентов с почечной и печеночной недостаточностью
На фоне лечения препаратом Гроприносин® следует каждые 2 недели проводить контроль содержания мочевой кислоты в сыворотке крови и в моче. Контроль активности печеночных ферментов рекомендуется проводить каждые 4 недели при длительных курсах лечения препаратом.
Полная инструкция
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Гроприносин таб.
Гроприносин таб., 500 мг, 20 шт.
5.0
(23)
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Инструкция

780 ₽

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У продавца:23 оценки·2 отзыва
У всех продавцов:104 оценки·22 отзыва
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user avatar
9 месяцев назад • vredina881mvt96 • Куплен на Маркете
Комментарий: Отличный недорогой препарат. В составе комплексной терапии помог справиться с ВПЧ за 2 месяца. Побочек не выявлено. Анализы уже больше 10 лет сдаю и всё чисто.
user avatar
7 месяцев назад • Яна Румянцева • Куплен на Маркете
Достоинства: Хороший препарат. Принимаю по схеме , назначенной врачом.
Комментарий: Подавляет ВПЧ
Посмотреть все отзывы на Маркете
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