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Ондансетрон-Альтфарм супп. рект., 16 мг, 2 шт.

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Коротко о товаре

Артикул Маркета
4453240105
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Чтобы вынуть суппозиторий из ячейковой упаковки, следует отломить одну ячейку с суппозиторием по насечке и разъединив края ленты, потянуть за них в разные стороны. Суппозиторий вводится в задний проход заостренным концом, по возможности глубоко. Для более удобного введения суппозитория рекомендуется нагнуться, присесть на корточки или лечь на бок, поджав ноги.\u003Cbr\u003E\nВыбор режима дозирования определяется выраженностью эметогенного действия проводимой противоопухолевой терапии.\u003Cbr\u003E\nПри умеренной эметогенной химиотерапии или радиотерапии:\u003Cbr\u003E\n- 16 мг ондансетрона за 1-2 ч до начала проведения основной терапии.\u003Cbr\u003E\nПри высокоэметогенной химиотерапии:\u003Cbr\u003E\nРекомендуемая доза составляет 16 мг одновременно с внутривенным введением 20 мг дексаметазона за 1 -2 часа до начала проведения химиотерапии.\u003Cbr\u003E\nДля профилактики поздней или длительной рвоты возникающей через 24 часа после окончания химиотерапии или радиотерапии, следует продолжить прием препарата в дозе 16 мг один раз в сутки в течение 5 дней.\u003Cbr\u003E\nДети. Ондансетрон в суппозиториях не рекомендован для применения у детей.\u003Cbr\u003E\nПациенты с нарушениями функции печени. Суточная доза ондансетрона для данной категории больных не должна превышать 8 мг в сутки."},{"name":"Побочные действия","value":"Аллергические реакции: крапивница, бронхоспазм, ларингоспазм, ангионевротический отек, анафилаксия.\u003Cbr\u003E\nСо стороны пищеварительной системы: икота, сухость во рту, запор или диарея, иногда бессимптомное преходящее повышение активности аминотрансфераз в сыворотке крови.\u003Cbr\u003E\nСо стороны сердечно-сосудистой системы: боли в грудной клетке, в ряде случаев с депрессией сегмента ST, аритмии, брадикардия, снижение артериального давления.\u003Cbr\u003E\nСо стороны нервной системы: головная боль, головокружение, спонтанные двигательные расстройства и судороги.\u003Cbr\u003E\nМестные реакции: гиперемия, боль, ощущение жжения в области ануса и прямой кишки после введения суппозитория.\u003Cbr\u003E\nПрочие: \"прилив\" крови к коже лица, чувство жара, временное нарушение остроты зрения, гипокалиемия, гиперкреатининемия."},{"name":"Фармакологическое действие","value":"Ондансетрон является селективным антагонистом рецепторов 5НТз (серотонина). Лекарственные средства для цитостатической химиотерапии и радиотерапия могут вызвать повышение уровня серотонина, который путем активации вагусных афферентных волокон, содержащих рецепторы 5-НТ3, вызывает рвотный рефлекс. Ондансетрон тормозит появление рвотного рефлекса путем блокады рецепторов 5-НТ3 на уровне нейронов как центральной, так и периферической нервной системы. По-видимому, на этом механизме действия основано предупреждение и лечение послеоперационной и вызванной цитостатической химио- и радио- терапией рвоты и тошноты."},{"name":"Фармакологическая группа","value":"противорвотное средство - серотониновых рецепторов антагонист"},{"name":"Форма выпуска","value":"суппозитории ректальные"},{"name":"Способ применения/введения","value":"ректальный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763742"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В сухом защищенном от света месте при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Имеется ограниченный опыт передозировки ондансетрона. В большинстве случаев симптомы похожи на побочные реакции при применении препарата в рекомендованных дозах. Лечение: симптоматическая и поддерживающая терапия. Специфический антидот для ондансетрона не известен."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Нет данных."},{"name":"Особые указания","value":"Пациенты, имевшие ранее аллергические реакции на др. селективные блокаторы 5-НТ3- рецепторов, имеют повышенный риск их развития на фоне ондансетрона. Ондансетрон может замедлять моторику толстого кишечника, в связи с чем, его назначение больным с признаками непроходимости кишечника требует особого наблюдения."},{"name":"Взаимодействие","value":"Нет данных о том, что ондансетрон индуцирует или ингибирует метаболизм других препаратов, часто назначаемых в комбинации с ним.\u003Cbr\u003E\nОндансетрон метаболизируется несколькими ферментами системы цитохрома Р450 (CYP3A4, CYP2D6 и CYP1A2): Угнетение или снижение активности одного из ферментов обычно в норме компенсируется другими, в связи с чем значимое снижение общего клиренса ондансетрона маловероятно. Тем не менее, требуется осторожность при совместном применении:\u003Cbr\u003E\n- с ферментативными индукторами Р450 (CYP2D6 и CYP3A) (барбитураты, карбамазепин, каризопродол, глютетимид, гризеофульвин, динитроген оксид, папаверин, фенилбутазон, фенитоин (вероятно и другие гидантоины), рифампицин, толбутамид);\u003Cbr\u003E\n- с ингибиторами ферментов Р450 (CYP2D6 и CYP3A) (аллопуринол, макролидные антибиотики, антидепрессанты - ингибиторы МАО, хлорамфеникол, циметидин, пероральные контрацептивы, содержащие эстрогены, дилтиазем, дисульфирам, вальпроевая кислота, вальпроат натрия, эритромицин, флуконазол, фторхинолоны, изониазид, кетоконазол, ловастатин, метронидазол, омепразол, пропранолол, хинидин, хинин, верапамил).\u003Cbr\u003E\nСпециальные исследования показали, что ондансетрон не взаимодействует с алкоголем, темазепамом, фуросемидом, трамадолом и пропофолом."},{"name":"Источник","value":"\u003Ca href=\"https://www.vidal.ru\" target=\"_blank\"\u003EСправочник лекарственных препаратов Видаль<\u002Fa\u003E"},{"name":"Регистрационный номер","value":"ЛСР-005842/08"},{"name":"Дата государственной регистрации","value":"20.07.2018"},{"name":"Владелец регистрационного удостоверения","value":"Альтфарм","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:16003328"]}}},{"name":"Изготовитель","value":"Альтфарм"},{"name":"Фасовщик","value":"Альтфарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Ондансетрон","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["17796364:17844711"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"18376389779078732178":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"пищеварительная система"},{"name":"Назначение","value":"рвота, тошнота"},{"name":"Показания к применению","value":"Предупреждение и устранение тошноты и рвоты, вызванных цитостатической химиотерапией и радиотерапией."},{"name":"Противопоказания","value":"- Повышенная чувствительность к ондансетрону или любому другому компоненту препарата.\u003Cbr\u003E\n- Беременность и период кормления грудью.\u003Cbr\u003E\n- Детский возраст."},{"name":"Состав","value":"1 суппозиторий содержит: активное вещество: ондансетрон гидрохлорид 4 мг, 8 мг или 16 мг вспомогательные вещества: витепсол Н 15"},{"name":"Действующее вещество","value":"Ондансетрон"},{"name":"Способ применения и дозы","value":"Препарат применяют ректально. 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Для более удобного введения суппозитория рекомендуется нагнуться, присесть на корточки или лечь на бок, поджав ноги.\u003Cbr\u003E\nВыбор режима дозирования определяется выраженностью эметогенного действия проводимой противоопухолевой терапии.\u003Cbr\u003E\nПри умеренной эметогенной химиотерапии или радиотерапии:\u003Cbr\u003E\n- 16 мг ондансетрона за 1-2 ч до начала проведения основной терапии.\u003Cbr\u003E\nПри высокоэметогенной химиотерапии:\u003Cbr\u003E\nРекомендуемая доза составляет 16 мг одновременно с внутривенным введением 20 мг дексаметазона за 1 -2 часа до начала проведения химиотерапии.\u003Cbr\u003E\nДля профилактики поздней или длительной рвоты возникающей через 24 часа после окончания химиотерапии или радиотерапии, следует продолжить прием препарата в дозе 16 мг один раз в сутки в течение 5 дней.\u003Cbr\u003E\nДети. Ондансетрон в суппозиториях не рекомендован для применения у детей.\u003Cbr\u003E\nПациенты с нарушениями функции печени. Суточная доза ондансетрона для данной категории больных не должна превышать 8 мг в сутки."},{"name":"Побочные действия","value":"Аллергические реакции: крапивница, бронхоспазм, ларингоспазм, ангионевротический отек, анафилаксия.\u003Cbr\u003E\nСо стороны пищеварительной системы: икота, сухость во рту, запор или диарея, иногда бессимптомное преходящее повышение активности аминотрансфераз в сыворотке крови.\u003Cbr\u003E\nСо стороны сердечно-сосудистой системы: боли в грудной клетке, в ряде случаев с депрессией сегмента ST, аритмии, брадикардия, снижение артериального давления.\u003Cbr\u003E\nСо стороны нервной системы: головная боль, головокружение, спонтанные двигательные расстройства и судороги.\u003Cbr\u003E\nМестные реакции: гиперемия, боль, ощущение жжения в области ануса и прямой кишки после введения суппозитория.\u003Cbr\u003E\nПрочие: \"прилив\" крови к коже лица, чувство жара, временное нарушение остроты зрения, гипокалиемия, гиперкреатининемия."},{"name":"Фармакологическое действие","value":"Ондансетрон является селективным антагонистом рецепторов 5НТз (серотонина). Лекарственные средства для цитостатической химиотерапии и радиотерапия могут вызвать повышение уровня серотонина, который путем активации вагусных афферентных волокон, содержащих рецепторы 5-НТ3, вызывает рвотный рефлекс. Ондансетрон тормозит появление рвотного рефлекса путем блокады рецепторов 5-НТ3 на уровне нейронов как центральной, так и периферической нервной системы. По-видимому, на этом механизме действия основано предупреждение и лечение послеоперационной и вызванной цитостатической химио- и радио- терапией рвоты и тошноты."},{"name":"Фармакологическая группа","value":"противорвотное средство - серотониновых рецепторов антагонист"},{"name":"Форма выпуска","value":"суппозитории ректальные"},{"name":"Способ применения/введения","value":"ректальный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В сухом защищенном от света месте при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Имеется ограниченный опыт передозировки ондансетрона. В большинстве случаев симптомы похожи на побочные реакции при применении препарата в рекомендованных дозах. Лечение: симптоматическая и поддерживающая терапия. Специфический антидот для ондансетрона не известен."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Нет данных."},{"name":"Особые указания","value":"Пациенты, имевшие ранее аллергические реакции на др. селективные блокаторы 5-НТ3- рецепторов, имеют повышенный риск их развития на фоне ондансетрона. Ондансетрон может замедлять моторику толстого кишечника, в связи с чем, его назначение больным с признаками непроходимости кишечника требует особого наблюдения."},{"name":"Взаимодействие","value":"Нет данных о том, что ондансетрон индуцирует или ингибирует метаболизм других препаратов, часто назначаемых в комбинации с ним.\u003Cbr\u003E\nОндансетрон метаболизируется несколькими ферментами системы цитохрома Р450 (CYP3A4, CYP2D6 и CYP1A2): Угнетение или снижение активности одного из ферментов обычно в норме компенсируется другими, в связи с чем значимое снижение общего клиренса ондансетрона маловероятно. Тем не менее, требуется осторожность при совместном применении:\u003Cbr\u003E\n- с ферментативными индукторами Р450 (CYP2D6 и CYP3A) (барбитураты, карбамазепин, каризопродол, глютетимид, гризеофульвин, динитроген оксид, папаверин, фенилбутазон, фенитоин (вероятно и другие гидантоины), рифампицин, толбутамид);\u003Cbr\u003E\n- с ингибиторами ферментов Р450 (CYP2D6 и CYP3A) (аллопуринол, макролидные антибиотики, антидепрессанты - ингибиторы МАО, хлорамфеникол, циметидин, пероральные контрацептивы, содержащие эстрогены, дилтиазем, дисульфирам, вальпроевая кислота, вальпроат натрия, эритромицин, флуконазол, фторхинолоны, изониазид, кетоконазол, ловастатин, метронидазол, омепразол, пропранолол, хинидин, хинин, верапамил).\u003Cbr\u003E\nСпециальные исследования показали, что ондансетрон не взаимодействует с алкоголем, темазепамом, фуросемидом, трамадолом и пропофолом."},{"name":"Источник","value":"\u003Ca href=\"https://www.vidal.ru\" target=\"_blank\"\u003EСправочник лекарственных препаратов Видаль<\u002Fa\u003E"},{"name":"Регистрационный номер","value":"ЛСР-005842/08"},{"name":"Дата государственной регистрации","value":"20.07.2018"},{"name":"Владелец регистрационного удостоверения","value":"Альтфарм"},{"name":"Изготовитель","value":"Альтфарм"},{"name":"Фасовщик","value":"Альтфарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Ондансетрон"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_14540152778182017612"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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Инструкция

Показания к применению

Предупреждение и устранение тошноты и рвоты, вызванных цитостатической химиотерапией и радиотерапией.

Противопоказания

- Повышенная чувствительность к ондансетрону или любому другому компоненту препарата.
- Беременность и период кормления грудью.
- Детский возраст.

Способ применения и дозы

Препарат применяют ректально. Чтобы вынуть суппозиторий из ячейковой упаковки, следует отломить одну ячейку с суппозиторием по насечке и разъединив края ленты, потянуть за них в разные стороны. Суппозиторий вводится в задний проход заостренным концом, по возможности глубоко. Для более удобного введения суппозитория рекомендуется нагнуться, присесть на корточки или лечь на бок, поджав ноги.
Выбор режима дозирования определяется выраженностью эметогенного действия проводимой противоопухолевой терапии.
При умеренной эметогенной химиотерапии или радиотерапии:
- 16 мг ондансетрона за 1-2 ч до начала проведения основной терапии.
При высокоэметогенной химиотерапии:
Рекомендуемая доза составляет 16 мг одновременно с внутривенным введением 20 мг дексаметазона за 1 -2 часа до начала проведения химиотерапии.
Для профилактики поздней или длительной рвоты возникающей через 24 часа после окончания химиотерапии или радиотерапии, следует продолжить прием препарата в дозе 16 мг один раз в сутки в течение 5 дней.
Дети. Ондансетрон в суппозиториях не рекомендован для применения у детей.
Пациенты с нарушениями функции печени. Суточная доза ондансетрона для данной категории больных не должна превышать 8 мг в сутки.
Полная инструкция
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Ондансетрон-Альтфарм супп. рект.
Ондансетрон-Альтфарм супп. рект., 16 мг, 2 шт.
4.0
(2)
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Задать вопрос
Инструкция

694 ₽

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4.0
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У продавца:2 оценки·2 отзыва
У всех продавцов:5 оценок·3 отзыва
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user avatar
Месяц назад • Елизавета З. • Куплен на Маркете
Комментарий: мне не помогло, увы
user avatar
3 месяца назад • Symhit • Куплен на Маркете
Комментарий: помогает
Посмотреть все отзывы на Маркете
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