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Описание

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Эналаприл таб., 5 мг, 28 шт.

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5.0
(5)
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Дозировка: 5 мг

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Коротко о товаре

Артикул Маркета
3123174160
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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гипертензия","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["36476390:36618511,36618237,36618158"]}}},{"name":"Показания к применению","value":"Артериальная гипертензия (в т.ч. реноваскулярная), хроническая сердечная недостаточность (в составе комбинированной терапии).\u003Cbr\u003EЭссенциальная гипертензия.\u003Cbr\u003EХроническая сердечная недостаточность (в составе комбинированной терапии).\u003Cbr\u003EПрофилактика развития клинически выраженной сердечной недостаточности у пациентов с бессимптомной дисфункцией левого желудочка (в составе комбинированной терапии).\u003Cbr\u003EПрофилактика коронарной ишемии у пациентов с дисфункцией левого желудочка с целью уменьшения частоты развития инфаркта миокарда и снижения частоты госпитализаций по поводу нестабильной стенокардии."},{"name":"Противопоказания","value":"Повышенная чувствительность к эналаприлу и другим ингибиторам АПФ, наличие в анамнезе ангионевротического отека, связанного с лечением ингибиторами АПФ, порфирия, беременность, период лактации, возраст до 18 лет (эффективность и безопасность не установлены)."},{"name":"Состав","value":"Действующее вещество: эналаприла малеат – 20 мг\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат — 116,400 мг, магния карбонат — 120,000 мг, желатин — 10,700 мг, кросповидон — 10,700 мг, магния стеарат — 2,200 мг\u003Cbr/\u003EДействующее вещество: эналаприла малеат – 10 мг\u003Cbr\u003EВспомогательные вещества: актоза 139.5 мг, целлюлоза микрокристаллическая 20 мг, повидон 6 мг, кроскармеллоза натрия 8 мг, кремния диоксид коллоидный 2 мг, магния стеарат 2 мг.\u003Cbr/\u003E: Действующее вещество: эналаприла малеат – 5 мг\u003Cbr\u003EВспомогательные вещества: лактоза 139.5 мг, целлюлоза микрокристаллическая 20 мг, повидон 6 мг, кроскармеллоза натрия 8 мг, кремния диоксид коллоидный 2 мг, магния стеарат 2 мг.\u003Cbr/\u003E"},{"name":"Действующее вещество","value":"Эналаприл","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28710182"]}}},{"name":"Способ применения и дозы","value":"Назначают внутрь независимо от времени приема пищи.\u003Cbr\u003EПри монотерапии артериальной гипертензии - начальная доза 5 мг 1 раз в сутки.\u003Cbr\u003EПри отсутствии клинического эффекта через 1-2 недели дозу повышают на 5 мг. После приема начальной дозы больные должны находиться под медицинским наблюдением в течение 2 ч и дополнительно 1 ч, пока не стабилизируется АД. При необходимости и достаточно хорошей переносимости, дозу можно увеличить до 40 мг/сут в 2 приема Через 2- 3 недели переходят на поддерживающую дозу - 10 - 40 мг/сут, разделенную на 1-2 приема. При умеренной артериальной гипертензии средняя суточная доза составляет около 10 мг Максимальная суточная доза препарата составляет 40 мг/сут.\u003Cbr\u003EВ случае назначения пациентам, одновременно получающим диуретики, лечение диуретиком необходимо прекратить за 2-3 дня до назначения Эналаприла. Если это невозможно, то начальная доза препарата должна составлять 2,5 мг/сут.\u003Cbr\u003EБольным с гипонатриемией (концентрация ионов натрия в сыворотке крови менее 130ммоль/л) или концентрацией креатинина в сыворотке крови более 0,14 ммоль/л начальная доза - 2,5 мг 1 раз в сутки.\u003Cbr\u003EПри реноваскулярной гипертензии начальная доза - 2,5 - 5 мг/сут. Максимальная суточная доза - 20 мг.\u003Cbr\u003EПри хронической сердечной недостаточности начальная доза составляет - 2,5 мг однократно, затем дозу увеличивают на 2,5 - 5 мг через каждые 3-4 дня в соответствии с клинической реакцией до максимально переносимых доз в зависимости от величины АД, но не выше 40 мг/сут. однократно или в 2 приема. У больных с низким систолическим АД (менее 110 мм рт.ст.) терапию следует начинать с дозы 1,25 мг. Подбор дозы должен проводиться в течение 2-4 нед. или в более короткие сроки. Средняя поддерживающая доза - 5 -20 мг/сут. за 1-2 приема.\u003Cbr\u003EУ пожилых чаще наблюдается более выраженный гипотензивный эффект и удлинение времени действия препарата, что связано с уменьшением скорости выведения эналаприла, поэтом) рекомендуемая начальная доза пожилым - 1,25 мг.\u003Cbr\u003EПри хронической почечной недостаточности кумуляция наступает при снижении фильтрации менее 10 мл/мин. При клиренсе креатинина (КК) 80-30 мл/мин доза обычно составляет 5 - 10 мг/сут, при КК до 30 -10 мл/мин - 2, 5 - 5 мг/сут, при КК менее 10 мл/мин - 1,25 - 2,5 мг/сут только в дни диализа.\u003Cbr\u003EДлительность лечения зависит от эффективности терапии. При слишком выраженном снижении АД дозу препарата постепенно уменьшают.\u003Cbr\u003EПрепарат применяют как в монотерапии, так и в сочетании с другими антигипертензивными средствами."},{"name":"Побочные действия","value":"Эналаприл в целом хорошо переносится и в большинстве случаев не вызывает побочных действий, требующих отмены препарата.\u003Cbr\u003EСо стороны сердечно-сосудистой системы чрезмерное снижение АД, ортостатический коллапс, редко - загрудинная боль, стенокардия, инфаркт миокарда (обычно связаны с выраженным снижением артериального давления), крайне редко аритмии (предсердная бради- или тахикардия, мерцание предсердий), сердцебиение, тромбоэмболия ветвей легочной артерии.\u003Cbr\u003EСо стороны центральной нервной системы: головокружение, головная боль, слабость, бессонница, тревога, спутанность сознания, повышенная утомляемость, сонливость (2-3%), очень редко при применении высоких доз - нервозность, депрессия, парестезии.\u003Cbr\u003EСо стороны органов чувств: нарушения вестибулярного аппарата, нарушения слуха и зрения, шум в ушах.\u003Cbr\u003EСо стороны пищеварительной системы: сухость во рту, анорексия, диспепсические расстройства (тошнота, диарея или запор, рвота, боль в области живота), кишечная непроходимость, панкреатит, нарушение функции печени и желчевыделения, гепатит, желтуха.\u003Cbr\u003EСо стороны дыхательной системы: непродуктивный сухой кашель, интерстициальный пневмонит, бронхоспазм, одышка, ринорея, фарингит.\u003Cbr\u003EАллергические реакции\\ кожная сыпь, зуд, крапивница, ангионевротический отек, крайне редко дисфония, полиморфная эритема, эксфолиативный дерматит, синдром Стивенса- Джонсона, токсический эпидермальный некролиз, пемфигус, фотосенсибилизация, серозит, васкулиг, миозит, артралгия, артрит, стоматит, глоссит.\u003Cbr\u003EСо стороны лабораторных показателей: гиперкреатининемия, повышение содержания мочевины, повышение активности \"печеночных\" ферментов, гипербилирубинемия, гиперкалиемия, гипонатриемия. Отмечаются в некоторых случаях снижение гематокрита, повышение СОЭ, тромбоцитопения, нейтропения, агранулоцитоз (у больных с аутоиммунными заболеваниями), эозинофилия.\u003Cbr\u003EСо стороны мочевыделительной системы: нарушение функции почек, редко протеинурия. Прочие: алопеция, снижение либидо, приливы."},{"name":"Фармакологическое действие","value":"Эналаприл - антигипертензивный препарат, из группы ингибиторов АПФ. Эналаприл является \"пролекарством\": в результате его гидролиза образуется эналаприлаг, который и ингибирует АПФ. Механизм его действия связан с уменьшением образования из ангиотензина I ангиотензина II, снижение содержания которого ведет к прямому уменьшению выделения альдостерона. При этом понижается общее периферическое сосудистое сопротивление, систолическое и диастолическое артериальное давление (АД), пост - и преднагрузка на миокард.\u003Cbr\u003EРасширяет артерии в большей степени, чем вены, при этом рефлекторного повышения частоты сердечных сокращений не отмечается.\u003Cbr\u003EГипотензивный эффект более выражен при высоком уровне ренина плазмы крови, чем при нормальном или сниженном его уровне. Снижение АД в терапевтических пределах не оказывает влияния на мозговое кровообращение, кровоток в сосудах мозга поддерживается на достаточном уровне и на фоне сниженного артериального давления. Усиливает коронарный и почечный кровоток.\u003Cbr\u003EПри длительном применении уменьшается гипертрофия левого желудочка миокарда и миоцитов стенок артерий резистивного типа, предотвращает прогрессирование сердечной недостаточности и замедляет развитие дилатации левого желудочка. Улучшает кровоснабжение ишемизированного миокарда. Снижает агрегацию тромбоцитов.\u003Cbr\u003EОбладает некоторым диуретическим эффектом.\u003Cbr\u003EВремя наступления гипотензивного эффекта при приеме внутрь - 1 ч, достигает максимума через А-6 ч и сохраняется до 24 ч. У некоторых больных для достижения оптимального уровня артериального давления необходима терапия на протяжении нескольких недель. При сердечной недостаточности заметный клинический эффект наблюдается при длительном лечении - 6 месяцев и более."},{"name":"Фармакологическая группа","value":"ингибиторы АПФ"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить в сухом, защищенном от света, недоступном для детей месте, при температуре не выше 25°С."},{"name":"Передозировка","value":"Симптомы: выраженное снижение АД вплоть до развития коллапса, инфаркта миокарда, острого нарушения мозгового кровообращения или тромбоэмболических осложнений, судороги, ступор.\u003Cbr\u003EЛечение: больного переводят в горизонтальное положение с низким изголовьем. В легких случаях показаны промывание желудка и прием внутрь солевого раствора, в более тяжелых случаях - мероприятия, направленные на стабилизацию АД: внутривенное введение физиологического раствора, плазмозаменителей, при необходимости - введение ангиотензина II, гемодиализ (скорость выведения эналаприлата - 62 мл/мин)."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В начале лечения, до завершения периода подбор дозы, необходимо воздерживаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, т.к. возможно головокружение, особенно после начальной дозы ингибитора АПФ у больных, принимающих диуретические средства."},{"name":"Особые указания","value":"Необходимо соблюдать осторожность при назначении пациентам со сниженным объемом циркулирующей крови (в результате терапии диуретиками, при ограничении потребления поваренной соли, проведении гемодиализа, диарее и рвоте) - повышен риск внезапного и выраженного снижения артериального давления после применения даже начальной дозы ингибиюра АПФ. Транзиторная артериальная гипотензия не является противопоказанием для продолжения лечения препаратом после стабилизации артериального давления (АД). В случае повторного выраженного снижения АД, следует уменьшить дозу или отменить препарат.\u003Cbr\u003EПрименение высокопроточных диализных мембран повышает риск развития анафилактической реакции. Коррекция режима дозирования в дни, свободные от диализа, должна осуществляться в зависимости от уровня АД. До и во время лечения ингибиторами АПФ необходим периодический контроль АД, показателей крови (гемоглобина, калия, креатинина, мочевины, активности ’’печеночных\" ферментов), белка в моче. Следует тщательно наблюдать за больными с тяжелой сердечной недостаточностью, ишемической болезнью сердца и заболеваниями сосудов мозга, у которых резкое снижение АД может привести к инфаркту миокарда, инсульту или нарушению функции почек. Внезапная отмена лечения не приводит к развитию синдрома \"рикошета\" (резкому подъему АД).\u003Cbr\u003EЗа новорожденными и грудными детьми, которые подвергались внутриутробному воздействию ингибиторов АПФ, рекомендуется вести тщательное наблюдение для своевременного выявления выраженного снижения АД, олигурии, гиперкалиемии и неврологических расстройств, возможных вследствие уменьшения почечного и мозгового кровотока при снижении артериального давления, вызываемого ингибиторами АПФ.\u003Cbr\u003EПри олигурии необходимо поддержание АД и почечной перфузии путем введения соответствующих жидкостей и сосудосуживающих средств. Перед исследованием функций паращитовидных желез следует отменить. Алкоголь усиливает гипотензивное действие препарата.\u003Cbr\u003EПеред хирургическим вмешательством (включая стоматологию) необходимо предупредить хирурга/ анестезиолога о применении ингибиторов АПФ.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EС осторожностью применять при первичном гиперальдостеронизме, двустороннем стенозе почечных артерий, стенозе артерии единственной почки, гиперкалиемии, состоянии после трансплантации почки; аортальном стенозе, митральном стенозе (с нарушениями гемодинамики), идиопатическом гипертрофическом субаортальном стенозе, системных заболеваниях соединительной ткани, ишемической болезни сердца, цереброваскулярных заболеваниях, сахарном диабете, почечной недостаточности протеинурия более 1 г/сут.), печеночной недостаточности, у пациентов, соблюдающих диету с ограничением соли или находящихся на гемодиализе, при одновременном приеме с иммунодепрессантами и салуретиками, у пожилых людей (старше 65 лет)."},{"name":"Взаимодействие","value":"При одновременном назначении эналаприла с нестероидными противовоспалительными препаратами (НПВП) возможно снижение гипотензивного эффекта эналаприла; с калийсберегающими диуретиками (спиронолактон, триамтерен, амилорид) может привести к гиперкалиемии; с солями лития - к замедлению выведения лития (показан контроль концентрации лития в плазме крови).\u003Cbr\u003EОдновременный прием с жаропонижающими и болеутоляющими средствами может уменьшить эффективность препарата.\u003Cbr\u003EЭналаприл ослабляет действие препаратов, содержащих теофиллин.\u003Cbr\u003EГипотензивное действие эналаприла усиливают диуретики, бета-адреноблокаторы, метилдола, нитраты, блокаторы \"медленных\" кальциевых каналов дигидропиридинового ряда, гидралазин, празозин.\u003Cbr\u003EИммунодепрессанты, аллопуринол, цитостатики усиливают гематотоксичность. Препараты, вызывающие угнетение костного мозга, повышают риск развития нейтропении и/или агранулоцитоза."},{"name":"Регистрационный номер","value":"ЛCP-001800/07"},{"name":"Дата государственной регистрации","value":"05.07.2018"},{"name":"Владелец регистрационного удостоверения","value":"ПФК Обновление","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:16815730"]}}},{"name":"Изготовитель","value":"ПФК Обновление"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Эналаприл","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:17893201"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"9596161270405262105":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносная система, кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия, хроническая сердечная недостаточность, эссенциальная гипертензия"},{"name":"Показания к применению","value":"Артериальная гипертензия (в т.ч. реноваскулярная), хроническая сердечная недостаточность (в составе комбинированной терапии).\u003Cbr\u003EЭссенциальная гипертензия.\u003Cbr\u003EХроническая сердечная недостаточность (в составе комбинированной терапии).\u003Cbr\u003EПрофилактика развития клинически выраженной сердечной недостаточности у пациентов с бессимптомной дисфункцией левого желудочка (в составе комбинированной терапии).\u003Cbr\u003EПрофилактика коронарной ишемии у пациентов с дисфункцией левого желудочка с целью уменьшения частоты развития инфаркта миокарда и снижения частоты госпитализаций по поводу нестабильной стенокардии."},{"name":"Противопоказания","value":"Повышенная чувствительность к эналаприлу и другим ингибиторам АПФ, наличие в анамнезе ангионевротического отека, связанного с лечением ингибиторами АПФ, порфирия, беременность, период лактации, возраст до 18 лет (эффективность и безопасность не установлены)."},{"name":"Состав","value":"Действующее вещество: эналаприла малеат – 20 мг\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат — 116,400 мг, магния карбонат — 120,000 мг, желатин — 10,700 мг, кросповидон — 10,700 мг, магния стеарат — 2,200 мг\u003Cbr/\u003EДействующее вещество: эналаприла малеат – 10 мг\u003Cbr\u003EВспомогательные вещества: актоза 139.5 мг, целлюлоза микрокристаллическая 20 мг, повидон 6 мг, кроскармеллоза натрия 8 мг, кремния диоксид коллоидный 2 мг, магния стеарат 2 мг.\u003Cbr/\u003E: Действующее вещество: эналаприла малеат – 5 мг\u003Cbr\u003EВспомогательные вещества: лактоза 139.5 мг, целлюлоза микрокристаллическая 20 мг, повидон 6 мг, кроскармеллоза натрия 8 мг, кремния диоксид коллоидный 2 мг, магния стеарат 2 мг.\u003Cbr/\u003E"},{"name":"Действующее вещество","value":"Эналаприл"},{"name":"Способ применения и дозы","value":"Назначают внутрь независимо от времени приема пищи.\u003Cbr\u003EПри монотерапии артериальной гипертензии - начальная доза 5 мг 1 раз в сутки.\u003Cbr\u003EПри отсутствии клинического эффекта через 1-2 недели дозу повышают на 5 мг. После приема начальной дозы больные должны находиться под медицинским наблюдением в течение 2 ч и дополнительно 1 ч, пока не стабилизируется АД. При необходимости и достаточно хорошей переносимости, дозу можно увеличить до 40 мг/сут в 2 приема Через 2- 3 недели переходят на поддерживающую дозу - 10 - 40 мг/сут, разделенную на 1-2 приема. При умеренной артериальной гипертензии средняя суточная доза составляет около 10 мг Максимальная суточная доза препарата составляет 40 мг/сут.\u003Cbr\u003EВ случае назначения пациентам, одновременно получающим диуретики, лечение диуретиком необходимо прекратить за 2-3 дня до назначения Эналаприла. Если это невозможно, то начальная доза препарата должна составлять 2,5 мг/сут.\u003Cbr\u003EБольным с гипонатриемией (концентрация ионов натрия в сыворотке крови менее 130ммоль/л) или концентрацией креатинина в сыворотке крови более 0,14 ммоль/л начальная доза - 2,5 мг 1 раз в сутки.\u003Cbr\u003EПри реноваскулярной гипертензии начальная доза - 2,5 - 5 мг/сут. Максимальная суточная доза - 20 мг.\u003Cbr\u003EПри хронической сердечной недостаточности начальная доза составляет - 2,5 мг однократно, затем дозу увеличивают на 2,5 - 5 мг через каждые 3-4 дня в соответствии с клинической реакцией до максимально переносимых доз в зависимости от величины АД, но не выше 40 мг/сут. однократно или в 2 приема. У больных с низким систолическим АД (менее 110 мм рт.ст.) терапию следует начинать с дозы 1,25 мг. Подбор дозы должен проводиться в течение 2-4 нед. или в более короткие сроки. Средняя поддерживающая доза - 5 -20 мг/сут. за 1-2 приема.\u003Cbr\u003EУ пожилых чаще наблюдается более выраженный гипотензивный эффект и удлинение времени действия препарата, что связано с уменьшением скорости выведения эналаприла, поэтом) рекомендуемая начальная доза пожилым - 1,25 мг.\u003Cbr\u003EПри хронической почечной недостаточности кумуляция наступает при снижении фильтрации менее 10 мл/мин. При клиренсе креатинина (КК) 80-30 мл/мин доза обычно составляет 5 - 10 мг/сут, при КК до 30 -10 мл/мин - 2, 5 - 5 мг/сут, при КК менее 10 мл/мин - 1,25 - 2,5 мг/сут только в дни диализа.\u003Cbr\u003EДлительность лечения зависит от эффективности терапии. При слишком выраженном снижении АД дозу препарата постепенно уменьшают.\u003Cbr\u003EПрепарат применяют как в монотерапии, так и в сочетании с другими антигипертензивными средствами."},{"name":"Побочные действия","value":"Эналаприл в целом хорошо переносится и в большинстве случаев не вызывает побочных действий, требующих отмены препарата.\u003Cbr\u003EСо стороны сердечно-сосудистой системы чрезмерное снижение АД, ортостатический коллапс, редко - загрудинная боль, стенокардия, инфаркт миокарда (обычно связаны с выраженным снижением артериального давления), крайне редко аритмии (предсердная бради- или тахикардия, мерцание предсердий), сердцебиение, тромбоэмболия ветвей легочной артерии.\u003Cbr\u003EСо стороны центральной нервной системы: головокружение, головная боль, слабость, бессонница, тревога, спутанность сознания, повышенная утомляемость, сонливость (2-3%), очень редко при применении высоких доз - нервозность, депрессия, парестезии.\u003Cbr\u003EСо стороны органов чувств: нарушения вестибулярного аппарата, нарушения слуха и зрения, шум в ушах.\u003Cbr\u003EСо стороны пищеварительной системы: сухость во рту, анорексия, диспепсические расстройства (тошнота, диарея или запор, рвота, боль в области живота), кишечная непроходимость, панкреатит, нарушение функции печени и желчевыделения, гепатит, желтуха.\u003Cbr\u003EСо стороны дыхательной системы: непродуктивный сухой кашель, интерстициальный пневмонит, бронхоспазм, одышка, ринорея, фарингит.\u003Cbr\u003EАллергические реакции\\ кожная сыпь, зуд, крапивница, ангионевротический отек, крайне редко дисфония, полиморфная эритема, эксфолиативный дерматит, синдром Стивенса- Джонсона, токсический эпидермальный некролиз, пемфигус, фотосенсибилизация, серозит, васкулиг, миозит, артралгия, артрит, стоматит, глоссит.\u003Cbr\u003EСо стороны лабораторных показателей: гиперкреатининемия, повышение содержания мочевины, повышение активности \"печеночных\" ферментов, гипербилирубинемия, гиперкалиемия, гипонатриемия. Отмечаются в некоторых случаях снижение гематокрита, повышение СОЭ, тромбоцитопения, нейтропения, агранулоцитоз (у больных с аутоиммунными заболеваниями), эозинофилия.\u003Cbr\u003EСо стороны мочевыделительной системы: нарушение функции почек, редко протеинурия. Прочие: алопеция, снижение либидо, приливы."},{"name":"Фармакологическое действие","value":"Эналаприл - антигипертензивный препарат, из группы ингибиторов АПФ. Эналаприл является \"пролекарством\": в результате его гидролиза образуется эналаприлаг, который и ингибирует АПФ. Механизм его действия связан с уменьшением образования из ангиотензина I ангиотензина II, снижение содержания которого ведет к прямому уменьшению выделения альдостерона. При этом понижается общее периферическое сосудистое сопротивление, систолическое и диастолическое артериальное давление (АД), пост - и преднагрузка на миокард.\u003Cbr\u003EРасширяет артерии в большей степени, чем вены, при этом рефлекторного повышения частоты сердечных сокращений не отмечается.\u003Cbr\u003EГипотензивный эффект более выражен при высоком уровне ренина плазмы крови, чем при нормальном или сниженном его уровне. Снижение АД в терапевтических пределах не оказывает влияния на мозговое кровообращение, кровоток в сосудах мозга поддерживается на достаточном уровне и на фоне сниженного артериального давления. Усиливает коронарный и почечный кровоток.\u003Cbr\u003EПри длительном применении уменьшается гипертрофия левого желудочка миокарда и миоцитов стенок артерий резистивного типа, предотвращает прогрессирование сердечной недостаточности и замедляет развитие дилатации левого желудочка. Улучшает кровоснабжение ишемизированного миокарда. Снижает агрегацию тромбоцитов.\u003Cbr\u003EОбладает некоторым диуретическим эффектом.\u003Cbr\u003EВремя наступления гипотензивного эффекта при приеме внутрь - 1 ч, достигает максимума через А-6 ч и сохраняется до 24 ч. У некоторых больных для достижения оптимального уровня артериального давления необходима терапия на протяжении нескольких недель. При сердечной недостаточности заметный клинический эффект наблюдается при длительном лечении - 6 месяцев и более."},{"name":"Фармакологическая группа","value":"ингибиторы АПФ"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить в сухом, защищенном от света, недоступном для детей месте, при температуре не выше 25°С."},{"name":"Передозировка","value":"Симптомы: выраженное снижение АД вплоть до развития коллапса, инфаркта миокарда, острого нарушения мозгового кровообращения или тромбоэмболических осложнений, судороги, ступор.\u003Cbr\u003EЛечение: больного переводят в горизонтальное положение с низким изголовьем. В легких случаях показаны промывание желудка и прием внутрь солевого раствора, в более тяжелых случаях - мероприятия, направленные на стабилизацию АД: внутривенное введение физиологического раствора, плазмозаменителей, при необходимости - введение ангиотензина II, гемодиализ (скорость выведения эналаприлата - 62 мл/мин)."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В начале лечения, до завершения периода подбор дозы, необходимо воздерживаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, т.к. возможно головокружение, особенно после начальной дозы ингибитора АПФ у больных, принимающих диуретические средства."},{"name":"Особые указания","value":"Необходимо соблюдать осторожность при назначении пациентам со сниженным объемом циркулирующей крови (в результате терапии диуретиками, при ограничении потребления поваренной соли, проведении гемодиализа, диарее и рвоте) - повышен риск внезапного и выраженного снижения артериального давления после применения даже начальной дозы ингибиюра АПФ. Транзиторная артериальная гипотензия не является противопоказанием для продолжения лечения препаратом после стабилизации артериального давления (АД). В случае повторного выраженного снижения АД, следует уменьшить дозу или отменить препарат.\u003Cbr\u003EПрименение высокопроточных диализных мембран повышает риск развития анафилактической реакции. Коррекция режима дозирования в дни, свободные от диализа, должна осуществляться в зависимости от уровня АД. До и во время лечения ингибиторами АПФ необходим периодический контроль АД, показателей крови (гемоглобина, калия, креатинина, мочевины, активности ’’печеночных\" ферментов), белка в моче. Следует тщательно наблюдать за больными с тяжелой сердечной недостаточностью, ишемической болезнью сердца и заболеваниями сосудов мозга, у которых резкое снижение АД может привести к инфаркту миокарда, инсульту или нарушению функции почек. Внезапная отмена лечения не приводит к развитию синдрома \"рикошета\" (резкому подъему АД).\u003Cbr\u003EЗа новорожденными и грудными детьми, которые подвергались внутриутробному воздействию ингибиторов АПФ, рекомендуется вести тщательное наблюдение для своевременного выявления выраженного снижения АД, олигурии, гиперкалиемии и неврологических расстройств, возможных вследствие уменьшения почечного и мозгового кровотока при снижении артериального давления, вызываемого ингибиторами АПФ.\u003Cbr\u003EПри олигурии необходимо поддержание АД и почечной перфузии путем введения соответствующих жидкостей и сосудосуживающих средств. Перед исследованием функций паращитовидных желез следует отменить. Алкоголь усиливает гипотензивное действие препарата.\u003Cbr\u003EПеред хирургическим вмешательством (включая стоматологию) необходимо предупредить хирурга/ анестезиолога о применении ингибиторов АПФ.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EС осторожностью применять при первичном гиперальдостеронизме, двустороннем стенозе почечных артерий, стенозе артерии единственной почки, гиперкалиемии, состоянии после трансплантации почки; аортальном стенозе, митральном стенозе (с нарушениями гемодинамики), идиопатическом гипертрофическом субаортальном стенозе, системных заболеваниях соединительной ткани, ишемической болезни сердца, цереброваскулярных заболеваниях, сахарном диабете, почечной недостаточности протеинурия более 1 г/сут.), печеночной недостаточности, у пациентов, соблюдающих диету с ограничением соли или находящихся на гемодиализе, при одновременном приеме с иммунодепрессантами и салуретиками, у пожилых людей (старше 65 лет)."},{"name":"Взаимодействие","value":"При одновременном назначении эналаприла с нестероидными противовоспалительными препаратами (НПВП) возможно снижение гипотензивного эффекта эналаприла; с калийсберегающими диуретиками (спиронолактон, триамтерен, амилорид) может привести к гиперкалиемии; с солями лития - к замедлению выведения лития (показан контроль концентрации лития в плазме крови).\u003Cbr\u003EОдновременный прием с жаропонижающими и болеутоляющими средствами может уменьшить эффективность препарата.\u003Cbr\u003EЭналаприл ослабляет действие препаратов, содержащих теофиллин.\u003Cbr\u003EГипотензивное действие эналаприла усиливают диуретики, бета-адреноблокаторы, метилдола, нитраты, блокаторы \"медленных\" кальциевых каналов дигидропиридинового ряда, гидралазин, празозин.\u003Cbr\u003EИммунодепрессанты, аллопуринол, цитостатики усиливают гематотоксичность. Препараты, вызывающие угнетение костного мозга, повышают риск развития нейтропении и/или агранулоцитоза."},{"name":"Регистрационный номер","value":"ЛCP-001800/07"},{"name":"Дата государственной регистрации","value":"05.07.2018"},{"name":"Владелец регистрационного удостоверения","value":"ПФК Обновление"},{"name":"Изготовитель","value":"ПФК Обновление"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Эналаприл"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_11162448888296729255"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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68 ₽

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  • Эналаприл таб., 10 мг, 20 шт.
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    Рейтинг товара: 4.8 из 5
    на основе 55 оценок
    Цена 74 ₽
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  • Эналаприл Гексал таб., 20 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xqohaqmisq/toggleWishlist":{"skuId":"101922734880","productId":1811768949,"offerId":"L1f3_HTaFVpOmfS2d4dRYQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI9cz13wYQoIbG2PsCGMSc0Acg19zBBw==","sign":"0b3eBZPUi+KAm8Ee4GNaxtpo8Z/4VbR1TSZCvTvGSos="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xqohaqmisq/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл Гексал таб., 20 мг, 20 шт.

    Рейтинг товара: 4.5 из 5
    на основе 19 оценок
    Цена 91 ₽
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  • Эналаприл гексал таб., 10 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9p42g8kcbq/toggleWishlist":{"skuId":"228128571","productId":1401075667,"offerId":"KyPPW78WahYABokqtcbtkQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI0++KnAUQu+7jbBjEnNAHINfcwQc=","sign":"ZZyHI6RqSr0RUwydg7OXuTVXca9kY2Yy+fXaJ3IQPOg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9p42g8kcbq/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл гексал таб., 10 мг, 20 шт.

    Рейтинг товара: 4.6 из 5
    на основе 65 оценок
    Цена 79 ₽
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  • Эналаприл-ФПО таб., 5 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6ho7vbp58u8/toggleWishlist":{"skuId":"101824454783","productId":1770837939,"offerId":"XTNAD75rBT4B8GoplTMDQA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIs6+zzAYQ/8DXqfsCGLGLuggg19zBBw==","sign":"7u2kcSlT5EpQH++FMWzXdOyCMKhts05Z/ZKqHbXerf0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6ho7vbp58u8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл-ФПО таб., 5 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 5 оценок
    Цена 39 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6ho7vbp58u8/addToCartButton":{"offerId":"XTNAD75rBT4B8GoplTMDQA","skuId":"101824454783","pendingCartItem":{"productId":1770837939,"offerId":"XTNAD75rBT4B8GoplTMDQA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMlPmVOwoiK5CqHnVk5O0UVbevXTYmpkvUxlr4XTVemdI7bqdPK7HWFhrTE216flUATc6O4CoSCKJ0sCJnccOfplHXXhQpFKJC2QLO5ZvTmYWh1lthYAaSb0DDZ00yz9j-G4o6NMJyC3BVp5fXAy6t_qLGazLSoONIBA9FZPWC8ZAuEDfKYYD_wod53bs6YQ7cA,,","feeShow":"OTNDnItfwRMjN9MRHuEMMlPmVOwoiK5CqHnVk5O0UVbevXTYmpkvUxlr4XTVemdI7bqdPK7HWFhrTE216flUATc6O4CoSCKJ0sCJnccOfplHXXhQpFKJC2QLO5ZvTmYWh1lthYAaSb0DDZ00yz9j-G4o6NMJyC3BVp5fXAy6t_qLGazLSoONIBA9FZPWC8ZAuEDfKYYD_wod53bs6YQ7cA,,","skuId":"101824454783","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"39","currency":"RUR"},"hid":"15756887","name":"Эналаприл-ФПО таб., 5 мг, 20 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  • Эналаприл таб., 10 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cj1yk55npmc/toggleWishlist":{"skuId":"228095669","productId":1778174097,"offerId":"OEgb_NuXoJBrpswUUUqvLA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIkZHzzwYQte3hbBiV3dAHINfcwQc=","sign":"RORK7AUNAn2lBoMhD1kU2BX/yEeBreQJ4QvJoP7jrlM="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cj1yk55npmc/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл таб., 10 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 68 оценок
    Цена 38 ₽
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  • Эналаприл таб., 10 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wf3jp0llz8h/toggleWishlist":{"skuId":"228128572","productId":1401075814,"offerId":"-RdU6aNSPsSw9527P0BlcQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI5vCKnAUQvO7jbBiW954SINfcwQc=","sign":"kS42warLU3DGasKXrY0oxIEq+0QTTEASEY41gkUiqW4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wf3jp0llz8h/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл таб., 10 мг, 20 шт.

    Рейтинг товара: 4.3 из 5
    на основе 6 оценок
    Цена 74 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wf3jp0llz8h/addToCartButton":{"offerId":"-RdU6aNSPsSw9527P0BlcQ","skuId":"228128572","pendingCartItem":{"productId":1401075814,"offerId":"-RdU6aNSPsSw9527P0BlcQ","showPlaceId":"OTNDnItfwRMjN9MRHuEMMlPmVOwoiK5Cxj4PVOqAsiYtbqMzagTsyo6ayzoNQQRQbFnnKXwoH8huSw3IFXd4c23dhZeRctr0E1DZrsIKEvWtx6uVdBdt7XB4XnUvGcCr1siiHbx1NFkUhPANfkCVUaFYq4ACmzlVk06bxnUjSynkcF6087U7BcA5AYmpUjy-Dhhy5W8tb-7orfgUVRWXJQ,,","feeShow":"OTNDnItfwRMjN9MRHuEMMlPmVOwoiK5Cxj4PVOqAsiYtbqMzagTsyo6ayzoNQQRQbFnnKXwoH8huSw3IFXd4c23dhZeRctr0E1DZrsIKEvWtx6uVdBdt7XB4XnUvGcCr1siiHbx1NFkUhPANfkCVUaFYq4ACmzlVk06bxnUjSynkcF6087U7BcA5AYmpUjy-Dhhy5W8tb-7orfgUVRWXJQ,,","skuId":"228128572","shopId":4035369,"price":{"applicablePriceDiscounts":[],"value":"74","currency":"RUR"},"hid":"15756887","name":"Эналаприл таб., 10 мг, 20 шт.","label":"6y4slqdli7m","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":5151028,"key":"img_id8463187375067275907.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96WFVmZtSFtMyd00zHc5eP2a4OrrJritdvgtYloRnLnIZg8Srd0exOXXcAnFOWEqo9eExOIsRrFbP6tvjC-evPWmJ6ml97NlUtNqBWjI90dfmfn8wiJ0VDWBEptHmhMQ4AuUOwvxrSX-MEGdYaIF0M9jXwSBSPGHjYyFCVShZnycxLDKPo4y4-uFghkyfNR3quxzSApWo5LQX3eqDPMCuoxu4gtadEBmCdaUjSWmauUk2FLNw8oBMxlFHGlfzY8WUdqGzaKFw5yjMQuJyX2JkSU2DHYpiESxOp6Dg8MjSrvamtd6g0naoxpFQQAq92zHYGeovSfT5D7tu-rhIsR85ot8H1NLE6LSpJPvmSRj7YeOIwJPLE6ByCdk4z1WO_h-80yFoQbWwBy-h5E1Z0rq4q8ctKow2tPYRmDdjJqHXoi4cDfYPiqzhfPgnbYlVpMAC1tRDjz7MtayfhvKXaPTF0Uv8uIP1NbKterz5uzuHjxWEPOWowvUKH6d5Vn3rpNBAIi-83-UaIzks4Jvwz7CVPM--sMFCez_7KIFgnL0HLm_3c7mouq3_kOxkOGcU1DXHSoGAKiymM3evZVIOXh5VoQA7LbYipZyhU6IFDJC2Vs2xwiIeCrh6gy2NBeNM3_5lDc-SMRXXaPftK3yL2DCitPzp6PYC3l_TU_RZSJQRvkvoqLrAMEH8rSPzFX3o341-yFq8tB2OYgoNk-igul9JeDtjyNYP1Y9qdho0VQsAsMiGl8epB--0r-5lk1ifxYB7XeHBb9mPwJYwoh91G8WegFa3ptE6DW93Z1NDXeJghUnADYtdfzN_1TpoIvxFslz4WrUOnqRrWwygbarUjoAWZBX3cO3eIa3mtW32CkQWx1ucBFuB-4Q5pJ1i2QeaPYP-OLukHX_LsDPSYA_QsJikYx2a10HV8w4IIzBtuQx9u4wYymsr4MdFo-KYzHvVxgZgRqwgQm6Rl4fMLo9nNhYfXiyI7RvkP15OZSMWcYYgi-_cbW0UNVwU5HxkxviR5hWlMVwqeBOGs3ZclyE_69gsifX2qWQ2BhL3uQi11FxFQQP09-mjggKER6YOtOyHE6hlpQcWLh101m2BEetLLhfxYFsWbxW9eWHT1jBBSguY0_m0aOxtvwwb-JenZaPAhQQu-L5XSYXICIOHvhzzLahg7HQDqC0727Q2jzxNqPbRcYsBcicxT8mRP1pMLdU2RVun9B-8Gb6n7kan0y3tqPM6rayGuHCh4OiUhg8HPDvTXuUxDbx28bmUeWpI9lBqS7HvKHa2VMzcVL_C9BgtDvdV54KujSL7IOe5q__MH5dfh2TwFaUCpK1EcvTcbTiHVgWbk8KPZZYge0IpKGjVjeXQDkvlqS7NXKL8VgL_QZL41BnMfqWGt5Bu3BhyxvoPgF8O1rVuB1xUZE9MF60n4MZEiasAI0PRUZb4uH34FR5IP_qAyxfiGIaUs0rEUBZiMg14CuTnJ_5r7RZdRZ-89kEVbKHoey7KIHZbM1oMV0jbi4Ddw4budKwU9QES1QWchtJcAYqHCdB1oIcavXvkPEULxlsz5mKHmfkdJFzfUk5zJ9gvGNUQmKGRkbCVmz5MeOMDF4VDbl0N9vgEaccmxZFc4ukCgQRtYJ03XOAc-OQ7AkXOi3SCnRwFGYEs7p70HTEBdmnA3U87GPaZkUdWuTk6f_dzdbZf7RiPFi9fsS3dBy4hlAqXWe6TjL7225o4xRqVemlS9eOwPFU3wcjR5RDToLKUxnW2ZOf7Iubvt45WQEbUtOX0Qn918nKxCfgH7KQj0loBe8UDtc_X3mqVmF-tF7BXYn2Q21eHg1eJXbqfCFUofLR3LnfBFbfCrWK1u_a9gd5h7ctjfVCbZddtXXQuVY_1cTcyi4On1JW6yXrRtvolwU7Tal_V7G1C80B3cZY_lntWDNWRTZfEDg2o6mQ5ekTQmHM7AMrGpRIq7K6q04-6cvxtIdrEsfrO5pdcjrjRaRZIlfkOozwUWyMt11E2bAkBjQPj7tpwPoU56ax_2E2IjSUaP38RKIySp_xJeAqaA7wG7AWK95n73uLlrVUz10ylWE1XTuSouD0Lw9-owZwW6-84JEaj46fqFyErK7jlYAgDi6PjGIbUMKK9JISnvs317abWgUYGKJOTPt56XiL25C9CzkaKTMkuRWHEM0fZjOB3KJHoT1E3VHtcAbxarZlIpXSNFxbYTy3T03R5lUfpdRskKgv7Wf0pLv7WN6oVrLLTrArlqJ-FuvI3rV8k9dpVylS1Xr_O3ILfcxbU-ckdpAQU8xf76RKn3ceNwqARjL3oIoTVZvMWEO8IEbdjtDgnf39KgVq66jQitXPxqxPgzsU3K8iV5344aNLWyyKRGcd6PprkTtwpmbXRdEUbQWjVaFASoa7GuvdxBsirAp83wYz0rKfvTy2Ngk9FZUm6Xv7k8tCCuuKUdVp3HoYYRNtwIeJRUxON1Nr6p7jXN_jzaYfkI-63vJXwyE0XqWyA0X9QVBqEDduIkdu6fqJxTYC4hvB5Rj6e3fMragyo5z5waB_ms7wQyKwSC1M8oa-YV-wLeplDX1-CgxRCKXXsd6emRuIwZtCBkrVBi2z25FLwTLcQxtUyrtl1h88YvC_ye8ITO3TCwLHHJ87ja9_35GcyJluxSAkUQ9k_nSLjYOwMZcK2_kgUzo1A158BBPLJEJ_LtuQVfylO7y_5M0Ym78x7qzXkuoqRua0hOKPPte61GQ7umIh67t4uvSw1X6W7luJ2rfnA9aSGfP1ttA-D-BJtScQmnRZCNJhYUODkHptVDSRm731pGhsYpsaX_6MLC36n4MAaWPpwdvihHFxOEZmoJ9y7p-j7u7cRFZhDPIWaz4fcWwNFRIl2mpw2kPuecAD_O3McZ1NRzHmkGD_T8u38Vkjn0n_mpkFV4V4I3Ii30qqp38_G-imxc8rMCU5utNjX9KJpSfHE4GoI1EoECLYVgKM5tQkDBxpksWjkd8muiEYVp8jJFpA_TlQjdqyVy9M_2QsVwy5PKsoeDL2P-GSFmVY7uWLIiWkdq6Ph4Qp2A,,/b64e=1/sign=073f9e7edd6b42709a4f59bc4cd6ada3/keyno=MARKET_1/*","showUid":"17179807279685852675206007","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI5vCKnAUQvO7jbBiW954SINfcwQc=","sign":"kS42warLU3DGasKXrY0oxIEq+0QTTEASEY41gkUiqW4="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI5vCKnAUQvO7jbBiW954SINfcwQc=","sign":"kS42warLU3DGasKXrY0oxIEq+0QTTEASEY41gkUiqW4="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wf3jp0llz8h/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Эналаприл таб., 5 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mcsy8bombgb/toggleWishlist":{"skuId":"655918381","productId":1401075919,"offerId":"uga-ITYDioP0HINuz3bBHg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIz/GKnAUQrYriuAIY1qzBCCDX3MEH","sign":"Y0R9qfsrQ7i7TREwRwlmEivfj++SljMiyzjXfYhP5Ak="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mcsy8bombgb/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл таб., 5 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 13 оценок
    Цена 50 ₽
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  • Энап таб., 10 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-prvq2lm5lb/toggleWishlist":{"skuId":"228128575","productId":1401075469,"offerId":"J9wFPIn_u8gMsNZ_eujusA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIje6KnAUQv+7jbBi21YcEINfcwQc=","sign":"K2pkwl4WzpF1PlID3prBX0kYH771K2Kpn+k3ckJKydQ="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-prvq2lm5lb/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Энап таб., 10 мг, 20 шт.

    Рейтинг товара: 4.7 из 5
    на основе 44 оценки
    Цена 87 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-prvq2lm5lb/addToCartButton":{"offerId":"J9wFPIn_u8gMsNZ_eujusA","skuId":"228128575","pendingCartItem":{"productId":1401075469,"offerId":"J9wFPIn_u8gMsNZ_eujusA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMlPmVOwoiK5C7B_aV5QPsnay7-aSgri0KQnkp-ojbXWija76c2YcHBRibFQ59UzOCJy2cqHc6ya5Ld7EfvWf5D_xUmcev2bbU8MNeKiQiETUqejHpGguzHoWuhICT4DRansLJgtwPdhhV-f5SG9HPk2x6xpm9LCzXwB0YT7gEJhsUJlksqyVTkCy5lELlQAPgA,,","feeShow":"OTNDnItfwRMjN9MRHuEMMlPmVOwoiK5C7B_aV5QPsnay7-aSgri0KQnkp-ojbXWija76c2YcHBRibFQ59UzOCJy2cqHc6ya5Ld7EfvWf5D_xUmcev2bbU8MNeKiQiETUqejHpGguzHoWuhICT4DRansLJgtwPdhhV-f5SG9HPk2x6xpm9LCzXwB0YT7gEJhsUJlksqyVTkCy5lELlQAPgA,,","skuId":"228128575","shopId":77075781,"price":{"applicablePriceDiscounts":[],"value":"87","currency":"RUR"},"hid":"15756887","name":"Энап таб., 10 мг, 20 шт.","label":"l5zzzyopwkh","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4120567,"key":"img_id360293287441868637.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96UWkyu_L0koKQ_exNV66fDokDjh01NP3yetNr57LYErPs9dejrNTInwM8LrdL6YCNYymEz1gtQjOVAvMQQrqz1ShHzNmXKHqIoelvhRt2d-Cky_Mw-ehYbWdUpwm0rqgBuhMYVGgmpvT5RPz0wRT1xAvzH0EYtuyO3HRCRtphhnDEon58l3eTWEF07fmfrRPr1DvLl3VkDYpyNePVghyNKxZM-s9XL2SgW80RxvCYEHP85QGfvJANs2okkO0Q8CMjG1JhCsO6Mdx6MvXvNQUK5rkZ8CJVPEZc8McQe163b93jVWEXyYjAl62hReWKII40PKN-vvunXT2PTl87elETYX5-W0mg7HS6mbX04Dkw9WN-nZPik0mNQ-RTAovUzbuKmQyyJ_JM4HbWAMHb5ksgWpPvSiKtc5l3L6I-De_vssOoMIlGpdL2M9jojokjx4rykTfnFEbo4jxmTFI42qcUG2HYzclZOCfPa-tc2kJc0UErrcPszN6WTFcORcpxMrc-45qmCyareaSh9H6GsxWUu88e7F-D_jNzsEo49kZkyE79FfMqjWPRP2uD-zQ_oBBL1fzwkLYyR8yCo9SmmwljULrcGFhGTTCs5HEpihGQdfGFMLZKd_QNOCGd6RyF7Y73N2Wn4MlYHEBo4VWJjPCAYa8n6UwN2Rl9Ee7swGVUV5NM_2RTJD7qOiYg19G5WY6DT-LzS8DqIdGB6AQYC7zjvlRsg09BYB5IPVpgsobfansqj7WGftOH0H0Q4ftVpy0R-_sQpqBLwVjg6E-Mv6WptR0ISrM4Tk4hQtJSu_w5KWK3wMelllB_-maYphADH1ZQXq4l_mdgXfnKHKE428eIxKdJfvTDtTZGdTLSXBUP-BVMxTgm8t4-hF6ugf4QJrn3iXBEVJxv9Suf3HHPE3bzSF-hOYni_TtZXKMwQQWRStuqwtlgEHvyzUg8HZZ9P0uSsOjJmAOQASv51iSrXXXNW6MOdUY5rkF-QtoCrrB93h0fCoQFWxMzIZRblzYhtLTSQW_w1xykzFG7xmtEHYxoFzt15R3CDSMj-rqeBXZrWVAP3pVXL1jl9q9PngPi-k4wV9bP4hj_CWs8zqglfq2vTOQR-kA5oRvhgV9gZrYZHIvPUsrnE4xvlgicG9Re91e5sZv0eTosOm-YofooUNcQNVCtLC7NqDc9vIvVz7-RowRBUAYLXgIo3_tEhVw8OeR8B28ZMFCbtWlm8ndU7HXh9Qy-boY5gO91eIB5KzRVs_BXqRH1f-HrqmO5wVz-6WeWq8Cq2_8fw6AIm3hRxkH-L4qEm1wXMTyCHDQB2utFKw0DBvskEMFT8aASdQ8hE9rbVrD6ciBRG6WCy68pZZ-AGgeFdh_DqsXXKq3PPe6C9uXJ1HXdFsboE13RJKEOMTtNw3VPYsZ-6T8BHHgLXOyordyyww5Kbk0uA-w-EfFqb2ldAAEzSmdxEwQNpuI0Zla6MiAU41yG5I0ctq4ox_2hrhB38y6oNRahqrD8B7fNIFKZk16ulr82SJxki2hRLnt1AIWkt8Fk3KQbqswmvJetsEmUAsN8Mitbo6e1DVDBvuuUEzQhYkNzAI7-v8heqSBUlLJZOdHLcwQiAmavX2OoSD-LL5ZyrKgX8bcMgihwfqyDmGMexn7oQA2fc6rJsyte-_QDpdSJn_P7k7EZgmYairhYDeDfDp49XL46aL1rxv_jInxiF-OoKSWaCN9Bef3jhdQsco4k34w1YdojhTM79wNTWZuaTb65upulDiaPt22N9QFDmhzqg2SQoudvRLSxL68JSe35c_DJoSTWtVb_pKp3TEq_IbuROvh2Qzx0pSbqQ6OijMgfHlIx91DWaW7halSkZSonURzT1TeztPbYycoCVR3Pt-dqXaE0MycHkZBve9s5LH6XzLp1RNO0v5IlYxJWec2CY_o5Sxl-0l3ciFBT_OR5KPy97qvjAI8GP15glL_lEQLsLS-y71Efc83jb0ABCd8BKLVge8Enm4C3P7_eecqzB0VC_CGi71tI6KK5fmrU76UmQLD_04u1fs8OnxUOqyRIoqP1Qj1jIRa9uaHZTStRNw8rzVr16_76Dw8MmStnpRyWprUiahghKpo2xtr2PkP7jIzd1clLQ7FBHZQi0ozEhmLt_e40YvBqwDViqCdV_SpaoH_-q-hQ7A5OwLkNwXltDEm2dOpR2xMidYNRMVmuj9lg1-Vtjy5sODbGAaOyMmsqFnPm8SbgQUALQQ9H-l99mTo7hghPcWMBKgPlq9YVnxRAoLwQOce71f7PF9MW5DunLChX0sf0V41E1vshajjjrnHnS0OAL_s9aPQNCL46gzlHa6HArNvV2YytpEODfJPVkjHZc5VC-Sf-NXDJLgFQAesh-BOC-Jl4NsMEhnrA1xH1nDlXAToWsjzXR8nExGvY94EsY3L27bFj6qTph4FUXFcy9NNfDSzCDF8zL5BZf1yO1Yr_i5xcnRSMhKWeo0MjZZE2ZtkheNXj2zK_DSvNlqypo7jR_5AhFKMuaXvyTu8cXdTKbgJoRA0iB7aQ2lfmvaJInqba9HtAWMX-YfgAJsvW5I9z6h9s3-S0RNNPlTq8mPrFuKsD4VM6GzRZvOzglbezTUL8OeuzL3O-uRa0pW59k3HEFYbV4orldNxyXjfsG7kieJOCiYhuD2HffouJZsN_334RA2GpiFVkbYdZXEV_-3WRJDvHW2ylPsvN0r0HTBkvv0QCe-NcqjPbUGHm_wtXh-Eg_X_m59zXCxeRh8dS5NK1JN7i9p5XB9VHF7MAaOhn0_oe2dudgFYJlIoVH6z56_3ac7sTe5hS5VCmdhGplUryeRQnddNEfYXYniwnuOYFvrjWUnwkumLS44OmFknzXBmNQGTAzEOL4IxhNPFiz5B2pihV-Nag3u-bfOls3ozuOUCWZRv1CSxsO54P9h3jQdufUw73T8f9mJQFNx6NudOOIO3eAqscvJ9RdWdETyZsavbgfAcc6jE27zKaSkm6AtnRtUCx8e9XrzjVPLTmXQvGHwyhjSQ9vunpQoLxplAqhS3cfVcbD76Bk5RQOvQ_WrkiiMF6U,/b64e=1/sign=d8bc8d142663d3e607083b7bb82a2101/keyno=MARKET_1/*","showUid":"17179807279665748440706009","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIje6KnAUQv+7jbBi21YcEINfcwQc=","sign":"K2pkwl4WzpF1PlID3prBX0kYH771K2Kpn+k3ckJKydQ="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIje6KnAUQv+7jbBi21YcEINfcwQc=","sign":"K2pkwl4WzpF1PlID3prBX0kYH771K2Kpn+k3ckJKydQ="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-prvq2lm5lb/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Эналаприл таб., 5 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ikxwy3mw09/toggleWishlist":{"skuId":"101961265494","productId":1784961531,"offerId":"1JEagIIOXW8sasRTO_gklg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI+7OR0wYQ1uL16vsCGISpsggg19zBBw==","sign":"1FTLdbMZTtOWurLkZGVVC7hVDBQ9Z7GCp89uHVoQamc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ikxwy3mw09/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл таб., 5 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 7 оценок
    Цена 48 ₽
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  • Эналаприл Реневал таб., 10 мг, 28 шт.
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    Эналаприл Реневал таб., 10 мг, 28 шт.

    Рейтинг товара: 4.8 из 5
    на основе 4 оценки
    Цена 133 ₽
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  • Эналаприл Н таб., 25 мг + 10 мг, 60 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hmnvw1exvs9/toggleWishlist":{"skuId":"102260586820","productId":1778173625,"offerId":"xgS72RL6IIxOkAXLpyshZg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+cOKqZyckaNMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIuY3zzwYQxPLS+fwCGNfxzwYg19zBBw==","sign":"n8vH5/WTL4rzc08s/KKcPcsXNTcm09qQbNkuqOVWItA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hmnvw1exvs9/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл Н таб., 25 мг + 10 мг, 60 шт.

    Рейтинг товара: 4.9 из 5
    на основе 17 оценок
    Цена 429 ₽
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Инструкция

Показания к применению

Артериальная гипертензия (в т.ч. реноваскулярная), хроническая сердечная недостаточность (в составе комбинированной терапии).
Эссенциальная гипертензия.
Хроническая сердечная недостаточность (в составе комбинированной терапии).
Профилактика развития клинически выраженной сердечной недостаточности у пациентов с бессимптомной дисфункцией левого желудочка (в составе комбинированной терапии).
Профилактика коронарной ишемии у пациентов с дисфункцией левого желудочка с целью уменьшения частоты развития инфаркта миокарда и снижения частоты госпитализаций по поводу нестабильной стенокардии.

Противопоказания

Повышенная чувствительность к эналаприлу и другим ингибиторам АПФ, наличие в анамнезе ангионевротического отека, связанного с лечением ингибиторами АПФ, порфирия, беременность, период лактации, возраст до 18 лет (эффективность и безопасность не установлены).

Способ применения и дозы

Назначают внутрь независимо от времени приема пищи.
При монотерапии артериальной гипертензии - начальная доза 5 мг 1 раз в сутки.
При отсутствии клинического эффекта через 1-2 недели дозу повышают на 5 мг. После приема начальной дозы больные должны находиться под медицинским наблюдением в течение 2 ч и дополнительно 1 ч, пока не стабилизируется АД. При необходимости и достаточно хорошей переносимости, дозу можно увеличить до 40 мг/сут в 2 приема Через 2- 3 недели переходят на поддерживающую дозу - 10 - 40 мг/сут, разделенную на 1-2 приема. При умеренной артериальной гипертензии средняя суточная доза составляет около 10 мг Максимальная суточная доза препарата составляет 40 мг/сут.
В случае назначения пациентам, одновременно получающим диуретики, лечение диуретиком необходимо прекратить за 2-3 дня до назначения Эналаприла. Если это невозможно, то начальная доза препарата должна составлять 2,5 мг/сут.
Больным с гипонатриемией (концентрация ионов натрия в сыворотке крови менее 130ммоль/л) или концентрацией креатинина в сыворотке крови более 0,14 ммоль/л начальная доза - 2,5 мг 1 раз в сутки.
При реноваскулярной гипертензии начальная доза - 2,5 - 5 мг/сут. Максимальная суточная доза - 20 мг.
При хронической сердечной недостаточности начальная доза составляет - 2,5 мг однократно, затем дозу увеличивают на 2,5 - 5 мг через каждые 3-4 дня в соответствии с клинической реакцией до максимально переносимых доз в зависимости от величины АД, но не выше 40 мг/сут. однократно или в 2 приема. У больных с низким систолическим АД (менее 110 мм рт.ст.) терапию следует начинать с дозы 1,25 мг. Подбор дозы должен проводиться в течение 2-4 нед. или в более короткие сроки. Средняя поддерживающая доза - 5 -20 мг/сут. за 1-2 приема.
У пожилых чаще наблюдается более выраженный гипотензивный эффект и удлинение времени действия препарата, что связано с уменьшением скорости выведения эналаприла, поэтом) рекомендуемая начальная доза пожилым - 1,25 мг.
При хронической почечной недостаточности кумуляция наступает при снижении фильтрации менее 10 мл/мин. При клиренсе креатинина (КК) 80-30 мл/мин доза обычно составляет 5 - 10 мг/сут, при КК до 30 -10 мл/мин - 2, 5 - 5 мг/сут, при КК менее 10 мл/мин - 1,25 - 2,5 мг/сут только в дни диализа.
Длительность лечения зависит от эффективности терапии. При слишком выраженном снижении АД дозу препарата постепенно уменьшают.
Препарат применяют как в монотерапии, так и в сочетании с другими антигипертензивными средствами.
Полная инструкция
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Эналаприл таб.
Эналаприл таб., 5 мг, 28 шт.
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1 вопрос
Инструкция

68 ₽

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5.0
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