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Описание

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Парацетамол таб., 500 мг, 20 шт.

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5.0
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Количество штук в упаковке, шт.: 20

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Коротко о товаре

Артикул Маркета
3288332709
Тип препарата
Назначение
Действующее вещество
Форма выпуска
таблетки
Инструкция
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Кратность назначения - до 4 раз в сутки. Максимальная суточная доза - 4 г. У детей старше 12 лет рекомендуется соблюдать интервал между приемом препарата не менее 6 часов.\u003Cbr\u003E\nДетям средняя разовая доза зависит от массы тела ребенка и составляет 15 мг/яг 4 раза в сутки каждые 6 часов. Максимальная суточная доза не должна превышать 60 мг/кг в сутки.\u003Cbr\u003E\nМаксимальная суточная доза для детей старше 3-6 лег - 1000 мг, 6-9 лет - 1500 мг, 9-12 лет - 2000 мг. Кратность назначения - 3-4 раза в сутки.\u003Cbr\u003E\nМаксимальная продолжительность лечения без консультации врача - 3 дня (при приёме в качестве жаропонижающего лекарственного средства) и 5 дней (в качестве анальгезирующего).\u003Cbr\u003E\nУ пациентов с хроническими или декомпенсированными заболеваниями печени, с печеночной недостаточностью, хроническим алкоголизмом, у истощенных пациентов и при обезвоживании суточная доза не должна превышать 3 г.\u003Cbr\u003E\nУ пациентов с тяжелой почечной недостаточностью (клиренс креатинина \u003C10 мл / мин), рекомендуется применять препарат с интервалом не менее 8 часов."},{"name":"Побочные действия","value":"Со стороны органов пищеварения: редко - боль в животе, тошнота, рвота.\u003Cbr\u003E\nСо стороны печени и желчевыводящих путей: редко - повышение активности печеночных ферментов; частота неизвестна - печеночная недостаточность, гепатиты, некроз печени.\u003Cbr\u003E\nСо стороны органов кроветворения: очень редко - анемия, тромбоцитопения, лейкопения, нейтропения, агранулоцитоз; частота неизвестна - сульфогемаглобинемия, метгемоглобинемия.\u003Cbr\u003E\nСо стороны сердечно-сосудистой системы: редко - снижение или увеличение прогромбинового индекса, снижение артериального давления.\u003Cbr\u003E\nСо стороны иммунной системы: редко - аллергические реакции (в т.ч. кожная сыпь, зуд, крапивница, ангионевротический отек); очень редко - острый генерализованный экзантематозный пустулез, синдром Стивенса-Джонсона, токсический эпидермальный некролиз (синдром Лайелла), бронхоспазм (анальгетическая “бронхиальная астма) у предрасположенных лиц.\u003Cbr\u003E\nСо стороны центральной и периферической нервной системы: частота неизвестна - головокружение, психомоторное возбуждение, дезориентация (при приеме высоких доз).\u003Cbr\u003E\nСо стороны кожных покровов: частота неизвестна - экзантема.\u003Cbr\u003E\nПрочие: частота неизвестна - увеличение креатинина (в основном вторично, по отношению к гепаторенальному синдрому).\u003Cbr\u003E\nПри появлении побочных реакций прекратите прием препарата и обратитесь к врачу."},{"name":"Фармакологическое действие","value":"Парацетамол обладает анальгезирующим, жаропонижающим и крайне слабым противовоспалительным действием, что связано с его влиянием на центр терморегуляции в гипоталамусе и слабовыраженной способностью ингибировать синтез простагландинов в периферических тканях. Отсутствие блокирующего влияния на синтез простагландинов в периферических тканях обусловливает отсутствие у него отрицательного влияния на водно-солевой обмен (задержка ионов натрия и воды) ц слизистую оболочку желудочно-кишечного тракта."},{"name":"Фармакологическая группа","value":"анальгезирующее ненаркотическое средство"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763744"]}}},{"name":"Условия хранения","value":"В защищенном от света месте при температуре не выше 25 °С. \u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Повреждение печени у взрослых возможно при приеме 10 г или более парацетамола, прием внутрь 5 г или более парацетамола может привести к повреждению печени при наличии факторов риска (длительное лечение карбамазепином, фенобарбиталом, фенитоином, примидоном, рифампицином, зверобоем продырявленным или другими препаратами, которые являются индукторами микросомальных ферментов печени; злоупотребление этанолом, дефицит глутатиона, нарушение пищеварения, муковисцидоз, ВИЧ-инфекция, голодание, кахексия).\u003Cbr\u003EСимптомы:\u003Cbr\u003E\nКлиническая картина острой передозировки развивается в течение 24 ч после приема парацетамола.\u003Cbr\u003E\nПоявляются желудочно-кишечные расстройства (тошнота, рвота, снижение аппетита, ощущение дискомфорта в брюшной полости и (или) абдоминальная боль), бледность кожных покровов. При одномоментном введении взрослым 7,5 г и более или детям более 140 мг/кг происходит цитолиз гепатоцитов с полным и необратимым некрозом печени, развитием печеночной недостаточности, метаболического ацидоза и энцефалопатии, которые могут привести к коме и летальному исходу. Через 12-48 ч после введения парацетамола отмечается повышение активности микросомальных ферментов печени, лактатдегидрогеназы, концентрации билирубина и снижение содержания протромбина. Клинические симптомы повреждения печени проявляются через 2 суток после передозировки препарата и достигают максимума на 4-6 день.\u003Cbr\u003E\nПри передозировке возможна интоксикация, особенно у пожилых пациентов, детей, пациентов с заболеваниями печени (вызванных хроническим алкоголизмом), у пациентов с нарушениями питания, а также у пациентов, принимающих индукторы микросомальных ферментов печени, при этом может развиться молниеносный гепатит, печеночная недостаточность, холестатический гепатит, цитолитический гепатит, иногда с летальным исходом.\u003Cbr\u003E\nЛечение: Немедленная госпитализация.\u003Cbr\u003E\nОпределение количественного содержания парацетамола в плазме крови перед началом лечения в как можно более ранние сроки после передозировки. Введение донаторов SH- групп и предшественников синтеза глутатиона - метионина и ацетилцистеина - наиболее эффективно в первые 8 часов. Необходимость в проведении дополнительных терапевтических мероприятий (дальнейшее введение метионина, внутривенное введение ацетилцистеина) определяется в зависимости от концентрации парацетамола в крови, а также от времени, прошедшего после его применения. Симптоматическое лечение. Лабораторные исследования активности микросомальных ферментов печени следует проводить в начале лечения и затем - каждые 24 ч. В большинстве случаев активность микросомальных ферментов печени нормализуется в течение 1-2 недель. В очень тяжелых случаях может потребоваться пересадка печени."},{"name":"Применение при беременности и кормлении грудью","value":"Парацетамол проникает через плацентарный барьер. В исследованиях на животных и у людей не было выявлено какого-либо риска при применении препарата в период беременности или отрицательного воздействия парацетамола на развитие эмбриона и плода. Парацетамол может использоваться во время беременности, однако целесообразно использовать минимальные эффективные дозы и максимально коротким курсом.\u003Cbr\u003E\nВ небольших количествах проникает в грудное молоко. В исследованиях не было установлено отрицательного воздействия парацетамола на организм ребенка при грудном вскармливании."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При применении Парацетамола в рекомендуемом диапазоне доз влияние на способность к управлению транспортными средствами и занятие другими, потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций не установлено."},{"name":"Особые указания","value":"При продолжающемся лихорадочном синдроме на фоне применения парацетамола более 3 дней и болевом синдроме более 5 дней, требуется консультаций врача.\u003Cbr\u003E\nПациенты с дефицитом глутатиона подвержены передозировке, необходимо соблюдать меры предосторожности. Зарегистрированы случаи развития печеночной недостаточности и нарушений функции печени у пациентов с низким уровнем глутатиона, в частности, у крайне истощенных пациентов, страдающих анорексией, хроническим алкоголизмом или у пациентов с низким индексом массы тела.\u003Cbr\u003E\nРиск развития повреждений печени возрастает у пациентов с поражением печени при алкоголизме.\u003Cbr\u003E\nПрием парацетамола оказывает влияние на показатели лабораторных исследований при количественном определении глюкозы и мочевой кислоты в плазме.\u003Cbr\u003E\nВо время длительного лечения необходим контроль картины периферической крови и функционального состояния печени.\u003Cbr\u003E\nПарацетамол может вызывать серьезные кожные реакции, такие как синдром Стивенса-Джонсона, токсический эпидермальный некролиз, острый генерализованный экзантематозный пустулез, которые могут быть летальными. При первом проявлении сыпи или других реакций гиперчувствительности, применение препарата должно быть прекращено, следует немедленно обратиться к врачу. При обнаружении у пациента острого вирусного гепатита необходимо отменить прием препарата.\u003Cbr\u003E\nОдновременный прием с этанолом не рекомендуется.\u003Cbr\u003E\nНе принимать одновременно с другими препаратами, содержащими парацетамол."},{"name":"Взаимодействие","value":"Индукторы микросомальных ферментов печени\u003Cbr\u003E\nИндукторы микросомальных ферментов печени или потенциально гепатотоксичные вещества (например, алкоголь, рифампицин, изониазид, снотворные и противоэпилептические средства, включая фенобарбитал, фенитоин, карбамазепин и другие) повышают токсичность парацетамола, могут привести к поражению печени даже при нетоксичных дозах парацетамола, поэтому следует контролировать функцию печени.\u003Cbr\u003E\nФенитоин снижает эффективность парацетамола, следовательно, пациентам, принимающим фенитоин, следует избегать частого применения парацетамола, особенно в высоких дозах.\u003Cbr\u003E\nУрикозурические лекарственные средства\u003Cbr\u003E\nПарацетамол снижает эффективность урикозурических лекарственных средств.\u003Cbr\u003E\nХлорамфеникол\u003Cbr\u003E\nПарацетамол может увеличивать риск повышенной концентрации хлорамфеникола.\u003Cbr\u003E\n3идовудин\u003Cbr\u003E\nПарацетамол может увеличивать риск развития нейтропении, в связи с чем, следует контролировать гематологические показатели. Одновременное применение возможно лишь после консультации врача.\u003Cbr\u003E\nПробенецид\u003Cbr\u003E\nПробенецид уменьшает почти в два раза клиренс парацетамола, что требует сужения дозы парацетамола.\u003Cbr\u003E\nНепрямые антикоагулянты\u003Cbr\u003E\nМногократный прием парацетамола в течение более чем 4 дней увеличивает антикоагулянтный эффект. Следует проводить мониторинг международного нормализованного отношения (МНО) во время и после окончания одновременного применения парацетамола (особенно в высоких дозах и/или в течение продолжительного времени) и производных кумарина. Нерегулярный прием парацетамола не оказывает значимого влияния.\u003Cbr\u003E\nПропантелин и другие препараты, замедляющие эвакуацию из желудка\u003Cbr\u003E\nПропантелин и другие препараты, замедляющие эвакуацию из желудка, снижают скорость всасывания парацетамола, что может отсрочить или уменьшить наступление эффекта.\u003Cbr\u003E\nМетоклопрамид и домперидон\u003Cbr\u003E\nМетоклопрамид и домперидон увеличивает скорость всасывания парацетамола и, соответственно начало обезболивающего и жаропонижающего действия.\u003Cbr\u003E\nБарбитураты\u003Cbr\u003E\nДлительное применение барбитуратов снижает эффективность парацетамола.\u003Cbr\u003E\nЭтанол\u003Cbr\u003E\nЭтанол способствует развитию острого панкреатита.\u003Cbr\u003E\nНестероидные противовоспалительные препараты (НПВП)\u003Cbr\u003E\nДлительное совместное использование парацетамола и других НПВП повышает риск развития \"анальгетической\" нефропатии и почечного папиллярного некроза, наступления терминальной стадии почечной недостаточности.\u003Cbr\u003E\nСалицилаты\u003Cbr\u003E\nОдновременное длительное назначение парацетамола в высоких дозах и салицилатов повышает риск развития рака почки или мочевого пузыря.\u003Cbr\u003E\nДифлунисал\u003Cbr\u003E\nДифлунисал повышает плазменную концентрацию парацетамола на 50% - риск развития гепатотоксичности.\u003Cbr\u003E\nМиелотоксичные препараты\u003Cbr\u003E\nМиелотоксичные препараты усиливают проявления гематотоксичности препарата."},{"name":"Регистрационный номер","value":"ЛП-004242"},{"name":"Дата государственной регистрации","value":"12.04.2017"},{"name":"Владелец регистрационного удостоверения","value":"Атолл","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:17601668"]}}},{"name":"Изготовитель","value":"ОЗОН"},{"name":"Фасовщик","value":"ОЗОН"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Парацетамол","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:17982393"]}}},{"name":"Срок годности","value":"35 мес."}]}},"fullSpecsGrouped":{"16205357052483455938":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"нервная система"},{"name":"Назначение","value":"альгодисменорея, головная боль, зубная боль, лихорадочные состояния, мигрень"},{"name":"Показания к применению","value":"Жаропонижающее средство при острых респираторных заболеваниях и других инфекционно-воспалительных заболеваниях, сопровождающихся повышением температуры тела.\u003Cbr\u003E\nОбезболивающее средство при болевом синдроме слабой и умеренной выраженности: артралгия, миалгия, невралгия, мигрень, зубная и головная боль, альгодисменорея, боль при травмах и ожогах."},{"name":"Противопоказания","value":"- Повышенная чувствительность к парацетамолу или любому другому ингредиенту препарата;\u003Cbr\u003E\n- дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция;\u003Cbr\u003E\n- детский возраст до 3 лет (для данной лекарственной формы)."},{"name":"Состав","value":"Состав на одну таблетку 200 мг:\u003Cbr\u003EДействующее вещество: парацетамол - 200,0 мг.\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (сахар молочный) - 14,8 мг, повидон-К25 - 14,4 мг, кроскармеллоза натрия - 9,6 мг, магния стеарат - 1,2 мг.\u003Cbr\u003EСостав на одну таблетку 500 мг:\u003Cbr\u003EДействующее вещество: парацетамол - 500,0 мг.\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (сахар молочный) - 37,0 мг, повидон-К25 - 36,0 мг, кроскармеллоза натрия - 24,0 мг, магния стеарат - 3,0 мг."},{"name":"Действующее вещество","value":"Парацетамол"},{"name":"Способ применения и дозы","value":"Внутрь, с большим количеством жидкости, через 1-2 ч после приёма пищи (приём сразу после еды приводит к задержке наступления действия).\u003Cbr\u003E\nВзрослым и детям старше 12 лет (масса тела более 40 кг) разовая доза - 500 мг; максимальная разовая доза - 1 г. Кратность назначения - до 4 раз в сутки. Максимальная суточная доза - 4 г. У детей старше 12 лет рекомендуется соблюдать интервал между приемом препарата не менее 6 часов.\u003Cbr\u003E\nДетям средняя разовая доза зависит от массы тела ребенка и составляет 15 мг/яг 4 раза в сутки каждые 6 часов. Максимальная суточная доза не должна превышать 60 мг/кг в сутки.\u003Cbr\u003E\nМаксимальная суточная доза для детей старше 3-6 лег - 1000 мг, 6-9 лет - 1500 мг, 9-12 лет - 2000 мг. Кратность назначения - 3-4 раза в сутки.\u003Cbr\u003E\nМаксимальная продолжительность лечения без консультации врача - 3 дня (при приёме в качестве жаропонижающего лекарственного средства) и 5 дней (в качестве анальгезирующего).\u003Cbr\u003E\nУ пациентов с хроническими или декомпенсированными заболеваниями печени, с печеночной недостаточностью, хроническим алкоголизмом, у истощенных пациентов и при обезвоживании суточная доза не должна превышать 3 г.\u003Cbr\u003E\nУ пациентов с тяжелой почечной недостаточностью (клиренс креатинина \u003C10 мл / мин), рекомендуется применять препарат с интервалом не менее 8 часов."},{"name":"Побочные действия","value":"Со стороны органов пищеварения: редко - боль в животе, тошнота, рвота.\u003Cbr\u003E\nСо стороны печени и желчевыводящих путей: редко - повышение активности печеночных ферментов; частота неизвестна - печеночная недостаточность, гепатиты, некроз печени.\u003Cbr\u003E\nСо стороны органов кроветворения: очень редко - анемия, тромбоцитопения, лейкопения, нейтропения, агранулоцитоз; частота неизвестна - сульфогемаглобинемия, метгемоглобинемия.\u003Cbr\u003E\nСо стороны сердечно-сосудистой системы: редко - снижение или увеличение прогромбинового индекса, снижение артериального давления.\u003Cbr\u003E\nСо стороны иммунной системы: редко - аллергические реакции (в т.ч. кожная сыпь, зуд, крапивница, ангионевротический отек); очень редко - острый генерализованный экзантематозный пустулез, синдром Стивенса-Джонсона, токсический эпидермальный некролиз (синдром Лайелла), бронхоспазм (анальгетическая “бронхиальная астма) у предрасположенных лиц.\u003Cbr\u003E\nСо стороны центральной и периферической нервной системы: частота неизвестна - головокружение, психомоторное возбуждение, дезориентация (при приеме высоких доз).\u003Cbr\u003E\nСо стороны кожных покровов: частота неизвестна - экзантема.\u003Cbr\u003E\nПрочие: частота неизвестна - увеличение креатинина (в основном вторично, по отношению к гепаторенальному синдрому).\u003Cbr\u003E\nПри появлении побочных реакций прекратите прием препарата и обратитесь к врачу."},{"name":"Фармакологическое действие","value":"Парацетамол обладает анальгезирующим, жаропонижающим и крайне слабым противовоспалительным действием, что связано с его влиянием на центр терморегуляции в гипоталамусе и слабовыраженной способностью ингибировать синтез простагландинов в периферических тканях. Отсутствие блокирующего влияния на синтез простагландинов в периферических тканях обусловливает отсутствие у него отрицательного влияния на водно-солевой обмен (задержка ионов натрия и воды) ц слизистую оболочку желудочно-кишечного тракта."},{"name":"Фармакологическая группа","value":"анальгезирующее ненаркотическое средство"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте при температуре не выше 25 °С. \u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Повреждение печени у взрослых возможно при приеме 10 г или более парацетамола, прием внутрь 5 г или более парацетамола может привести к повреждению печени при наличии факторов риска (длительное лечение карбамазепином, фенобарбиталом, фенитоином, примидоном, рифампицином, зверобоем продырявленным или другими препаратами, которые являются индукторами микросомальных ферментов печени; злоупотребление этанолом, дефицит глутатиона, нарушение пищеварения, муковисцидоз, ВИЧ-инфекция, голодание, кахексия).\u003Cbr\u003EСимптомы:\u003Cbr\u003E\nКлиническая картина острой передозировки развивается в течение 24 ч после приема парацетамола.\u003Cbr\u003E\nПоявляются желудочно-кишечные расстройства (тошнота, рвота, снижение аппетита, ощущение дискомфорта в брюшной полости и (или) абдоминальная боль), бледность кожных покровов. При одномоментном введении взрослым 7,5 г и более или детям более 140 мг/кг происходит цитолиз гепатоцитов с полным и необратимым некрозом печени, развитием печеночной недостаточности, метаболического ацидоза и энцефалопатии, которые могут привести к коме и летальному исходу. Через 12-48 ч после введения парацетамола отмечается повышение активности микросомальных ферментов печени, лактатдегидрогеназы, концентрации билирубина и снижение содержания протромбина. Клинические симптомы повреждения печени проявляются через 2 суток после передозировки препарата и достигают максимума на 4-6 день.\u003Cbr\u003E\nПри передозировке возможна интоксикация, особенно у пожилых пациентов, детей, пациентов с заболеваниями печени (вызванных хроническим алкоголизмом), у пациентов с нарушениями питания, а также у пациентов, принимающих индукторы микросомальных ферментов печени, при этом может развиться молниеносный гепатит, печеночная недостаточность, холестатический гепатит, цитолитический гепатит, иногда с летальным исходом.\u003Cbr\u003E\nЛечение: Немедленная госпитализация.\u003Cbr\u003E\nОпределение количественного содержания парацетамола в плазме крови перед началом лечения в как можно более ранние сроки после передозировки. Введение донаторов SH- групп и предшественников синтеза глутатиона - метионина и ацетилцистеина - наиболее эффективно в первые 8 часов. Необходимость в проведении дополнительных терапевтических мероприятий (дальнейшее введение метионина, внутривенное введение ацетилцистеина) определяется в зависимости от концентрации парацетамола в крови, а также от времени, прошедшего после его применения. Симптоматическое лечение. Лабораторные исследования активности микросомальных ферментов печени следует проводить в начале лечения и затем - каждые 24 ч. В большинстве случаев активность микросомальных ферментов печени нормализуется в течение 1-2 недель. В очень тяжелых случаях может потребоваться пересадка печени."},{"name":"Применение при беременности и кормлении грудью","value":"Парацетамол проникает через плацентарный барьер. В исследованиях на животных и у людей не было выявлено какого-либо риска при применении препарата в период беременности или отрицательного воздействия парацетамола на развитие эмбриона и плода. Парацетамол может использоваться во время беременности, однако целесообразно использовать минимальные эффективные дозы и максимально коротким курсом.\u003Cbr\u003E\nВ небольших количествах проникает в грудное молоко. В исследованиях не было установлено отрицательного воздействия парацетамола на организм ребенка при грудном вскармливании."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При применении Парацетамола в рекомендуемом диапазоне доз влияние на способность к управлению транспортными средствами и занятие другими, потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций не установлено."},{"name":"Особые указания","value":"При продолжающемся лихорадочном синдроме на фоне применения парацетамола более 3 дней и болевом синдроме более 5 дней, требуется консультаций врача.\u003Cbr\u003E\nПациенты с дефицитом глутатиона подвержены передозировке, необходимо соблюдать меры предосторожности. Зарегистрированы случаи развития печеночной недостаточности и нарушений функции печени у пациентов с низким уровнем глутатиона, в частности, у крайне истощенных пациентов, страдающих анорексией, хроническим алкоголизмом или у пациентов с низким индексом массы тела.\u003Cbr\u003E\nРиск развития повреждений печени возрастает у пациентов с поражением печени при алкоголизме.\u003Cbr\u003E\nПрием парацетамола оказывает влияние на показатели лабораторных исследований при количественном определении глюкозы и мочевой кислоты в плазме.\u003Cbr\u003E\nВо время длительного лечения необходим контроль картины периферической крови и функционального состояния печени.\u003Cbr\u003E\nПарацетамол может вызывать серьезные кожные реакции, такие как синдром Стивенса-Джонсона, токсический эпидермальный некролиз, острый генерализованный экзантематозный пустулез, которые могут быть летальными. При первом проявлении сыпи или других реакций гиперчувствительности, применение препарата должно быть прекращено, следует немедленно обратиться к врачу. При обнаружении у пациента острого вирусного гепатита необходимо отменить прием препарата.\u003Cbr\u003E\nОдновременный прием с этанолом не рекомендуется.\u003Cbr\u003E\nНе принимать одновременно с другими препаратами, содержащими парацетамол."},{"name":"Взаимодействие","value":"Индукторы микросомальных ферментов печени\u003Cbr\u003E\nИндукторы микросомальных ферментов печени или потенциально гепатотоксичные вещества (например, алкоголь, рифампицин, изониазид, снотворные и противоэпилептические средства, включая фенобарбитал, фенитоин, карбамазепин и другие) повышают токсичность парацетамола, могут привести к поражению печени даже при нетоксичных дозах парацетамола, поэтому следует контролировать функцию печени.\u003Cbr\u003E\nФенитоин снижает эффективность парацетамола, следовательно, пациентам, принимающим фенитоин, следует избегать частого применения парацетамола, особенно в высоких дозах.\u003Cbr\u003E\nУрикозурические лекарственные средства\u003Cbr\u003E\nПарацетамол снижает эффективность урикозурических лекарственных средств.\u003Cbr\u003E\nХлорамфеникол\u003Cbr\u003E\nПарацетамол может увеличивать риск повышенной концентрации хлорамфеникола.\u003Cbr\u003E\n3идовудин\u003Cbr\u003E\nПарацетамол может увеличивать риск развития нейтропении, в связи с чем, следует контролировать гематологические показатели. Одновременное применение возможно лишь после консультации врача.\u003Cbr\u003E\nПробенецид\u003Cbr\u003E\nПробенецид уменьшает почти в два раза клиренс парацетамола, что требует сужения дозы парацетамола.\u003Cbr\u003E\nНепрямые антикоагулянты\u003Cbr\u003E\nМногократный прием парацетамола в течение более чем 4 дней увеличивает антикоагулянтный эффект. Следует проводить мониторинг международного нормализованного отношения (МНО) во время и после окончания одновременного применения парацетамола (особенно в высоких дозах и/или в течение продолжительного времени) и производных кумарина. Нерегулярный прием парацетамола не оказывает значимого влияния.\u003Cbr\u003E\nПропантелин и другие препараты, замедляющие эвакуацию из желудка\u003Cbr\u003E\nПропантелин и другие препараты, замедляющие эвакуацию из желудка, снижают скорость всасывания парацетамола, что может отсрочить или уменьшить наступление эффекта.\u003Cbr\u003E\nМетоклопрамид и домперидон\u003Cbr\u003E\nМетоклопрамид и домперидон увеличивает скорость всасывания парацетамола и, соответственно начало обезболивающего и жаропонижающего действия.\u003Cbr\u003E\nБарбитураты\u003Cbr\u003E\nДлительное применение барбитуратов снижает эффективность парацетамола.\u003Cbr\u003E\nЭтанол\u003Cbr\u003E\nЭтанол способствует развитию острого панкреатита.\u003Cbr\u003E\nНестероидные противовоспалительные препараты (НПВП)\u003Cbr\u003E\nДлительное совместное использование парацетамола и других НПВП повышает риск развития \"анальгетической\" нефропатии и почечного папиллярного некроза, наступления терминальной стадии почечной недостаточности.\u003Cbr\u003E\nСалицилаты\u003Cbr\u003E\nОдновременное длительное назначение парацетамола в высоких дозах и салицилатов повышает риск развития рака почки или мочевого пузыря.\u003Cbr\u003E\nДифлунисал\u003Cbr\u003E\nДифлунисал повышает плазменную концентрацию парацетамола на 50% - риск развития гепатотоксичности.\u003Cbr\u003E\nМиелотоксичные препараты\u003Cbr\u003E\nМиелотоксичные препараты усиливают проявления гематотоксичности препарата."},{"name":"Регистрационный номер","value":"ЛП-004242"},{"name":"Дата государственной регистрации","value":"12.04.2017"},{"name":"Владелец регистрационного удостоверения","value":"Атолл"},{"name":"Изготовитель","value":"ОЗОН"},{"name":"Фасовщик","value":"ОЗОН"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Парацетамол"},{"name":"Срок годности","value":"35 мес."}]}],"transitionId":"tr_9067076037882199492"}}}}
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78 ₽/шт

  • 11-13 июня, самовывоз • 0 ₽
POLZAru
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    на основе 55 оценок
    Цена 17 ₽
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  • Ибупрофен таб. п/о плен., 200 мг, 50 шт.
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    Ибупрофен таб. п/о плен., 200 мг, 50 шт.

    Рейтинг товара: 5 из 5
    на основе 239 оценок
    Цена 50 ₽
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  • Цефекон Д супп. рект., 50 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-1bxxaagqriz/toggleWishlist":{"skuId":"101392477730","productId":228004471,"offerId":"MG3iTf-n_Ji306-qcKA53Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+taoobaDv/sXEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI96TcbBCi3Nnb+QIY2fHPBiDt2cEH","sign":"O+aPzTNk3bf3MlTwLr+2A4GGX/YNYPjG7khq/5NH2z8="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-1bxxaagqriz/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Цефекон Д супп. рект., 50 мг, 10 шт.

    Рейтинг товара: 4.8 из 5
    на основе 115 оценок
    Цена 29 ₽
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  • Нурофен форте таб. п/о, 400 мг, 24 шт.
    –21 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-blvn0cljtyo/toggleWishlist":{"skuId":"101811995729","productId":228007914,"offerId":"Ubf8OfDNJ_ct9hCmmT_xZQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+taoobaDv/sXEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI6r/cbBDRiN+j+wIYrqmlBiDn3MEH","sign":"JKAcB7rGsvK3GpIup/FzlQIKtT+MsD6FGgxd3phtX6A="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-blvn0cljtyo/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нурофен форте таб. п/о, 400 мг, 24 шт.

    Рейтинг товара: 4.9 из 5
    на основе 176 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 215 ₽ вместо 217
    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  • Ибупрофен таб. п/о плен., 400 мг, 50 шт.
    –17 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-a2cdvch8gf4/toggleWishlist":{"skuId":"101392533732","productId":186557805,"offerId":"oIuRGZYDDFpf2-Hd5fu6jw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+taoobaDv/sXEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI7cr6WBDkkd3b+QIYsc2dBSDn3MEH","sign":"hGbggwO4IHr9nXJ7fNGO0qc1ISR3+MEFprqkqXxeKcc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-a2cdvch8gf4/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ибупрофен таб. п/о плен., 400 мг, 50 шт.

    Рейтинг товара: 4.9 из 5
    на основе 320 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 139 ₽ вместо 140
    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  • МИГ 400 таб. п/о плен., 400 мг, 20 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dzsjp8peq4s/toggleWishlist":{"skuId":"101822953725","productId":549337011,"offerId":"6lzxu5TqAHjw4gPLkrtTXw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+taoobaDv/sXEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIs+/4hQIQ/fH7qPsCGKfd0Acg59zBBw==","sign":"cX6sOCKJMk2IpCKqRbG8aGv+4kxIKxNXVe76wxzPeEw="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dzsjp8peq4s/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    МИГ 400 таб. п/о плен., 400 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 93 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 131 ₽ вместо 132
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  • Ибуклин таб. п/о плен., 400 мг+325 мг, 10 шт.
    –12 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8z1k0u3xebd/toggleWishlist":{"skuId":"101392133740","productId":186882821,"offerId":"O034OnFMdCnHGEs7sulgYg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+taoobaDv/sXEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIhbaOWRDs3MTb+QIYwKLVByDn3MEH","sign":"I0Wd/IFPHqU3mT3lo5brL98IegO/NRc/JUlTwZKgxZs="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8z1k0u3xebd/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ибуклин таб. п/о плен., 400 мг+325 мг, 10 шт.

    Рейтинг товара: 4.9 из 5
    на основе 172 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 192 ₽ вместо 194
    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таб. п/о плен., 400 мг+325 мг, 10 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  • Ацетилсалициловая кислота таб., 500 мг, 20 шт.
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    Ацетилсалициловая кислота таб., 500 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 35 ₽
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  • Пенталгин таб. п/о плен., 24 шт.
    –1 %
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    Пенталгин таб. п/о плен., 24 шт.

    Рейтинг товара: 4.8 из 5
    на основе 214 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 223 ₽ вместо 225
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Инструкция

Показания к применению

Жаропонижающее средство при острых респираторных заболеваниях и других инфекционно-воспалительных заболеваниях, сопровождающихся повышением температуры тела.
Обезболивающее средство при болевом синдроме слабой и умеренной выраженности: артралгия, миалгия, невралгия, мигрень, зубная и головная боль, альгодисменорея, боль при травмах и ожогах.

Противопоказания

- Повышенная чувствительность к парацетамолу или любому другому ингредиенту препарата;
- дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция;
- детский возраст до 3 лет (для данной лекарственной формы).

Способ применения и дозы

Внутрь, с большим количеством жидкости, через 1-2 ч после приёма пищи (приём сразу после еды приводит к задержке наступления действия).
Взрослым и детям старше 12 лет (масса тела более 40 кг) разовая доза - 500 мг; максимальная разовая доза - 1 г. Кратность назначения - до 4 раз в сутки. Максимальная суточная доза - 4 г. У детей старше 12 лет рекомендуется соблюдать интервал между приемом препарата не менее 6 часов.
Детям средняя разовая доза зависит от массы тела ребенка и составляет 15 мг/яг 4 раза в сутки каждые 6 часов. Максимальная суточная доза не должна превышать 60 мг/кг в сутки.
Максимальная суточная доза для детей старше 3-6 лег - 1000 мг, 6-9 лет - 1500 мг, 9-12 лет - 2000 мг. Кратность назначения - 3-4 раза в сутки.
Максимальная продолжительность лечения без консультации врача - 3 дня (при приёме в качестве жаропонижающего лекарственного средства) и 5 дней (в качестве анальгезирующего).
У пациентов с хроническими или декомпенсированными заболеваниями печени, с печеночной недостаточностью, хроническим алкоголизмом, у истощенных пациентов и при обезвоживании суточная доза не должна превышать 3 г.
У пациентов с тяжелой почечной недостаточностью (клиренс креатинина <10 мл / мин), рекомендуется применять препарат с интервалом не менее 8 часов.
Полная инструкция
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Парацетамол таб.
Парацетамол таб., 500 мг, 20 шт.
5.0
(4)
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Задать вопрос
Инструкция

78 ₽/шт

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5.0
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У продавца:4 оценки·1 отзыв
У всех продавцов:96 оценок·28 отзывов
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user avatar
Месяц назад • Елена Нугаева • Куплен на Маркете
Достоинства: Быстрая доставка.
Недостатки: нет
Комментарий: супер.
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