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Коротко о товаре

Артикул Маркета
3672106637
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 месяцев
Инструкция
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вспомогательные вещества: пропиленгликоль - 125,00 мг; глицерол (глицерин) - 106,25 мг; натрия ацетат тригидрат (натрия ацетат) - 15,00 мг; натрия сахаринат - 10,00 мг; вода очищенная - до 1,00 мл."},{"name":"Действующее вещество","value":"Цетиризин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["27144131:28708921"]}}},{"name":"Способ применения и дозы","value":"Внутрь, накапать в ложку или растворить в воде.\u003Cbr\u003EКоличество воды для растворения препарата должно соответствовать количеству жидкости, которое пациент (особенно ребенок) в состоянии проглотить.\u003Cbr\u003EРаствор следует принимать сразу после приготовления.\u003Cbr\u003EВзрослые\u003Cbr\u003E10 мг (20 капель) 1 раз в день.\u003Cbr\u003EЕсли через три дня после начала лечения улучшения не наступает, или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом.\u003Cbr\u003EПрименяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции.\u003Cbr\u003EПрименение у особых групп пациентов\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EНет необходимости в снижении дозы у пожилых пациентов, если функция почек не нарушена.\u003Cbr\u003EПациенты с почечной недостаточностью\u003Cbr\u003EПоскольку цетиризин выводится из организма в основном почками (см. подраздел \"Фармакокинетика\"), при невозможности альтернативного лечения пациентам с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины КК). Пациенты с нарушением функции печени\u003Cbr\u003EПациентам с нарушением только функции печени коррекции режима дозирования не требуется.\u003Cbr\u003EПациенты с сочетанием почечной и печеночной недостаточности\u003Cbr\u003EРекомендуется коррекция дозирования (см. таблицу выше).\u003Cbr\u003EДети\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем.\u003Cbr\u003EДети от 6 месяцев до 12 месяцев\u003Cbr\u003E2,5 мг (5 капель) 1 раз в день.\u003Cbr\u003EДети от 1 года до 6 лет\u003Cbr\u003E2,5 мг (5 капель) 2 раза в день.\u003Cbr\u003EДети от 6 до 12 лет\u003Cbr\u003E5 мг (10 капель) 2 раза в день.\u003Cbr\u003EДети старше 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день.\u003Cbr\u003EИногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.\u003Cbr\u003EДетям с почечной недостаточностью дозу корректируют с учетом КК и массы тела."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной организации здравоохранения (ВОЗ):\u003Cbr\u003Eочень часто ≥1/10;\u003Cbr\u003Eчасто от ≥ 1/100 до \u003C 1/10;\u003Cbr\u003Eнечасто от ≥ 1/1000 до \u003C 1/100;\u003Cbr\u003Eредко от ≥ 1/10000 до \u003C 1/1000;\u003Cbr\u003Eочень редко \u003C 1/10000, включая отдельные сообщения;\u003Cbr\u003Eчастота неизвестна - по имеющимся данным установить частоту возникновения не представляется возможным.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eочень редко - тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eредко - реакции гиперчувствительности;\u003Cbr\u003Eочень редко - анафилактический шок.\u003Cbr\u003EНарушения метаболизма и питания:\u003Cbr\u003Eредко - повышение массы тела;\u003Cbr\u003Eчастота неизвестна - повышение аппетита.\u003Cbr\u003EПсихические нарушения:\u003Cbr\u003Eнечасто - возбуждение;\u003Cbr\u003Eредко - агрессия, спутанность сознания, депрессия, галлюцинации;\u003Cbr\u003Eчастота неизвестна - суицидальные идеи, нарушения сна (включая кошмарные сновидения).\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто - парестезии; редко - судороги;\u003Cbr\u003Eочень редко - извращение вкуса, дискинезия, дистония, обморок, тремор;\u003Cbr\u003Eчастота неизвестна - нарушение памяти, в том числе амнезия, глухота.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eочень редко - нарушение аккомодации, нечеткость зрения, нистагм;\u003Cbr\u003Eчастота неизвестна - васкулит.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринта:\u003Cbr\u003Eчастота неизвестна - вертиго.\u003Cbr\u003EНарушения со стороны сердца:\u003Cbr\u003Eредко - тахикардия.\u003Cbr\u003EЖелудочно-кишечные нарушения:\u003Cbr\u003Eнечасто - диарея.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eредко - печеночная недостаточность с изменением функциональных печеночных проб (повышение активности трансаминаз, щелочной фосфатазы, гаммаглутамилтрансферазы и билирубина);\u003Cbr\u003Eчастота неизвестна - гепатит.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто - сыпь, зуд;\u003Cbr\u003Eредко - крапивница;\u003Cbr\u003Eочень редко - ангионевротический отек, стойкая лекарственная эритема;\u003Cbr\u003Eчастота неизвестна - острый генерализованный экзантематозный пустулез.\u003Cbr\u003EНарушения со стороны мышечной, скелетной и соединительной ткани:\u003Cbr\u003Eчастота неизвестна - артралгия.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eочень редко - дизурия, энурез;\u003Cbr\u003Eчастота неизвестна - задержка мочи.\u003Cbr\u003EОбщие нарушения и реакции в месте введения:\u003Cbr\u003Eнечасто - астения, недомогание;\u003Cbr\u003Eредко - периферические отеки.\u003Cbr\u003EОписание отдельных нежелательных реакций\u003Cbr\u003EПосле прекращения применения цетиризина были отмечены случаи зуда, в том числе интенсивного зуда и/или крапивницы.\u003Cbr\u003EЕсли у Вас отмечаются побочные эффекты, указанные в инструкции, или они усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Цетиризин является метаболитом гидроксизина, относится к группе конкурентных антагонистов гистамина и блокирует H1-гистаминовые рецепторы.\u003Cbr\u003EВ дополнение к антигистаминному эффекту цетиризин предупреждает развитие и облегчает течение аллергических реакций: в дозе 10 мг один или два раза в день ингибирует позднюю фазу агрегации эозинофилов в коже и конъюнктиве пациентов, подверженных атопии.\u003Cbr\u003EКлиническая эффективность и безопасность\u003Cbr\u003EИсследования на здоровых добровольцах показали, что цетиризин в дозах 5 или 10 мг значительно ингибирует реакцию в виде сыпи и покраснения на введение в кожу гистамина в высокой концентрации, однако корреляция с эффективностью не установлена. В 6-недельном плацебо-контролируемом исследовании с участием 186 пациентов с аллергическим ринитом и сопутствующей бронхиальной астмой легкого и среднетяжелого течения показано, что прием цетиризина в дозе 10 мг один раз в сутки уменьшает симптомы ринита и не влияет на функцию легких.\u003Cbr\u003EРезультаты данного исследования подтверждают безопасность применения цетиризина у пациентов, страдающих аллергией и бронхиальной астмой легкого и среднетяжелого течения.\u003Cbr\u003EВ плацебо-контролируемом исследовании показано, что прием цетиризина в дозе 60 мг в сутки в течение 7 дней не вызывал клинически значимого удлинения интервала QT.\u003Cbr\u003EПрием цетиризина в рекомендуемой дозе показал улучшение качества жизни пациентов с круглогодичным и сезонным аллергическим ринитами.\u003Cbr\u003EДети\u003Cbr\u003EВ 35-дневном исследовании с участием пациентов в возрасте 5-12 лет не выявлено признаков невосприимчивости к антигистаминному эффекту цетиризина. Нормальная реакция кожи на гистамин восстанавливалась в течение трех дней после отмены цетиризина при его неоднократном применении.\u003Cbr\u003EВ 7-дневном плацебо-контролируемом исследовании цетиризина в лекарственной форме \"сироп\" с участием 42 пациентов в возрасте от 6 до 11 месяцев продемонстрирована безопасность его применения. Цетиризин назначался в дозе 0,25 мг/кг два раза в день, что приблизительно соответствовало 4,5 мг в день (диапазон доз составлял от 3,4 до 6,2 мг в день).\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем."},{"name":"Фармакологическая группа","value":"противоаллергическое средство - H1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"капли для приема внутрь"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 6 месяцев"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте.\u003Cbr\u003EОткрытый флакон хранить не более 6 месяцев."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003EПосле однократного приема цетиризина в дозе 50 мг наблюдались следующие симптомы: спутанность сознания, головокружение, сонливость, ступор, слабость, беспокойство, седативный эффект, повышенная утомляемость, головная боль, мидриаз, зуд, тахикардия, тремор, задержка мочи, диарея, недомогание.\u003Cbr\u003EЛечение\u003Cbr\u003EНемедленно после приема препарата - промывание желудка или стимуляция рвоты. Рекомендуется прием активированного угля, проведение симптоматической и поддерживающей терапии. Специфического антидота нет. Гемодиализ неэффективен."},{"name":"Применение при беременности и кормлении грудью","value":"При анализе проспективных данных более чем 700 случаев исходов беременности не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью.\u003Cbr\u003EЭкспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и постнатальное развитие.\u003Cbr\u003EАдекватных и строго контролируемых клинических исследований по безопасности применения цетиризина у беременных женщин не проводилось, поэтому препарат противопоказан при беременности.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EНе следует применять препарат в период грудного вскармливания, так как цетиризин экскретируется с грудным молоком.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии цетиризина на фертильность человека ограничены, однако отрицательного влияния на фертильность не выявлено."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При объективной оценке способности к вождению автотранспорта и управлению механизмами достоверно не выявлено каких-либо нежелательных явлений при приеме цетиризина в рекомендуемой дозе. Однако пациентам с проявлениями сонливости на фоне приема препарата целесообразно воздерживаться от управления автомобилем, занятий потенциально опасными видами деятельности или управления механизмами, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Ввиду потенциального угнетающего влияния на ЦНС следует соблюдать осторожность при назначении цетиризина детям в возрасте до 1 года при наличии следующих ограничивающих факторов риска возникновения синдрома внезапной детской смерти, таких, как (но не ограничиваясь этим списком):\u003Cbr\u003E- синдром апноэ во сне или синдром внезапной детской смерти детей грудного возраста у брата или сестры;\u003Cbr\u003E- злоупотребление матери наркотиками или курением во время беременности;\u003Cbr\u003E- молодой возраст матери (19 лет и моложе);\u003Cbr\u003E- злоупотребление курением няни, ухаживающей за ребенком (одна пачка сигарет в день или более);\u003Cbr\u003E- дети, регулярно засыпающие лицом вниз и которых не укладывают на спину;\u003Cbr\u003E- недоношенные (менее 37 недель гестации) или рожденные с недостаточной массой тела (ниже 10-го перцентиля от гестационного возраста) дети;\u003Cbr\u003E- при совместном приеме препаратов, оказывающих угнетающее влияние на ЦНС.\u003Cbr\u003EУ пациентов с повреждениями спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов к задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи. Рекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем.\u003Cbr\u003EОсторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что Н1-гистаминовых рецепторов блокаторы ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EПосле прекращения применения цетиризина может появиться зуд и/или крапивница, даже если эти симптомы отсутствовали в начале лечения. В некоторых случаях симптомы могут быть интенсивными и требовать возобновления приема цетиризина. Симптомы исчезают при возобновлении приема цетиризина."},{"name":"Взаимодействие","value":"Одновременное применение с азитромицином, циметидином, эритромицином, кетоконазолом или псевдоэфедрином не влияет на фармакокинетические параметры цетиризина. Фармакокинетических взаимодействий не наблюдалось.\u003Cbr\u003EСогласно испытаниям in vitro, цетиризин не влияет на эффект связывания варфарина с белками.\u003Cbr\u003EОдновременный прием азитромицина, эритромицина, кетоконазола, теофиллина и псевдоэфедрина не выявил существенных изменений в клинических лабораторных показателях, жизненно важных функциях и ЭКГ.\u003Cbr\u003EВ исследовании с одновременным приемом теофиллина (400 мг в день) и цетиризина (20 мг в день) было обнаружено незначительное, но статистически достоверное, повышение 24-часовой AUC (площади под кривой) на 19% для цетиризина и на 11% для теофиллина. Кроме того, максимальные уровни в плазме крови увеличились до 7,7% и 6,4% соответственно для цетиризина и теофиллина. Одновременно клиренс цетиризина уменьшился на -16%, а также на -10% в случае теофиллина, когда цетиризин принимали пациенты, которые ранее получали лечение теофиллином. Тем не менее предварительное лечение цетиризином не оказало существенного влияния на фармакокинетические параметры теофиллина.\u003Cbr\u003EПосле однократного приема цетиризина в дозе 10 мг эффект алкоголя (0,8%) значительно не усиливался; статистически значимое взаимодействие с 5 мг диазепама было доказано в одном из 16 психометрических тестов.\u003Cbr\u003EОдновременный прием 10 мг цетиризина в день с глипизидом привел к незначительному снижению показателей глюкозы. Этот эффект не имеет клинического значения. Тем не менее рекомендуется раздельный прием - глипизид утром и цетиризин вечером.\u003Cbr\u003EЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные), перед применением препарата проконсультируйтесь с врачом."},{"name":"Регистрационный номер","value":"ЛП-005501"},{"name":"Дата государственной регистрации","value":"29.04.2019"},{"name":"Владелец регистрационного удостоверения","value":"Вертекс","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34324371:35649313","7893318:8514228"]}}},{"name":"Изготовитель","value":"Вертекс"},{"name":"Фасовщик","value":"Вертекс"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Цетиризин-Вертекс","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["17796364:19681032"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"8176588108152087883":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"глаза, кожа, носовая полость"},{"name":"Назначение","value":"аллергический конъюнктивит, аллергический ринит, крапивница, сезонная аллергия"},{"name":"Показания к применению","value":"Взрослым, детям с 6 месяцев и старше для облегчения:\u003Cbr\u003E- назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита, таких как зуд, чихание, заложенность носа, ринорея, слезотечение, гиперемия конъюнктивы;\u003Cbr\u003E- симптомов хронической идиопатической крапивницы.\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем."},{"name":"Противопоказания","value":"Повышенная чувствительность к цетиризину, гидроксизину или приоизводным пиперазина, а также к другим компонентам препарата;\u003Cbr\u003E- терминальная стадия почечной недостаточности (КК \u003C 10 мл/мин);\u003Cbr\u003E- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности);\u003Cbr\u003E- беременность."},{"name":"Состав","value":"1 мл капель содержит: действующее вещество: цетиризина дигидрохлорид - 10,00 мг; вспомогательные вещества: пропиленгликоль - 125,00 мг; глицерол (глицерин) - 106,25 мг; натрия ацетат тригидрат (натрия ацетат) - 15,00 мг; натрия сахаринат - 10,00 мг; вода очищенная - до 1,00 мл."},{"name":"Действующее вещество","value":"Цетиризин"},{"name":"Способ применения и дозы","value":"Внутрь, накапать в ложку или растворить в воде.\u003Cbr\u003EКоличество воды для растворения препарата должно соответствовать количеству жидкости, которое пациент (особенно ребенок) в состоянии проглотить.\u003Cbr\u003EРаствор следует принимать сразу после приготовления.\u003Cbr\u003EВзрослые\u003Cbr\u003E10 мг (20 капель) 1 раз в день.\u003Cbr\u003EЕсли через три дня после начала лечения улучшения не наступает, или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом.\u003Cbr\u003EПрименяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции.\u003Cbr\u003EПрименение у особых групп пациентов\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EНет необходимости в снижении дозы у пожилых пациентов, если функция почек не нарушена.\u003Cbr\u003EПациенты с почечной недостаточностью\u003Cbr\u003EПоскольку цетиризин выводится из организма в основном почками (см. подраздел \"Фармакокинетика\"), при невозможности альтернативного лечения пациентам с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины КК). Пациенты с нарушением функции печени\u003Cbr\u003EПациентам с нарушением только функции печени коррекции режима дозирования не требуется.\u003Cbr\u003EПациенты с сочетанием почечной и печеночной недостаточности\u003Cbr\u003EРекомендуется коррекция дозирования (см. таблицу выше).\u003Cbr\u003EДети\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем.\u003Cbr\u003EДети от 6 месяцев до 12 месяцев\u003Cbr\u003E2,5 мг (5 капель) 1 раз в день.\u003Cbr\u003EДети от 1 года до 6 лет\u003Cbr\u003E2,5 мг (5 капель) 2 раза в день.\u003Cbr\u003EДети от 6 до 12 лет\u003Cbr\u003E5 мг (10 капель) 2 раза в день.\u003Cbr\u003EДети старше 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день.\u003Cbr\u003EИногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.\u003Cbr\u003EДетям с почечной недостаточностью дозу корректируют с учетом КК и массы тела."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной организации здравоохранения (ВОЗ):\u003Cbr\u003Eочень часто ≥1/10;\u003Cbr\u003Eчасто от ≥ 1/100 до \u003C 1/10;\u003Cbr\u003Eнечасто от ≥ 1/1000 до \u003C 1/100;\u003Cbr\u003Eредко от ≥ 1/10000 до \u003C 1/1000;\u003Cbr\u003Eочень редко \u003C 1/10000, включая отдельные сообщения;\u003Cbr\u003Eчастота неизвестна - по имеющимся данным установить частоту возникновения не представляется возможным.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eочень редко - тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eредко - реакции гиперчувствительности;\u003Cbr\u003Eочень редко - анафилактический шок.\u003Cbr\u003EНарушения метаболизма и питания:\u003Cbr\u003Eредко - повышение массы тела;\u003Cbr\u003Eчастота неизвестна - повышение аппетита.\u003Cbr\u003EПсихические нарушения:\u003Cbr\u003Eнечасто - возбуждение;\u003Cbr\u003Eредко - агрессия, спутанность сознания, депрессия, галлюцинации;\u003Cbr\u003Eчастота неизвестна - суицидальные идеи, нарушения сна (включая кошмарные сновидения).\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто - парестезии; редко - судороги;\u003Cbr\u003Eочень редко - извращение вкуса, дискинезия, дистония, обморок, тремор;\u003Cbr\u003Eчастота неизвестна - нарушение памяти, в том числе амнезия, глухота.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eочень редко - нарушение аккомодации, нечеткость зрения, нистагм;\u003Cbr\u003Eчастота неизвестна - васкулит.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринта:\u003Cbr\u003Eчастота неизвестна - вертиго.\u003Cbr\u003EНарушения со стороны сердца:\u003Cbr\u003Eредко - тахикардия.\u003Cbr\u003EЖелудочно-кишечные нарушения:\u003Cbr\u003Eнечасто - диарея.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eредко - печеночная недостаточность с изменением функциональных печеночных проб (повышение активности трансаминаз, щелочной фосфатазы, гаммаглутамилтрансферазы и билирубина);\u003Cbr\u003Eчастота неизвестна - гепатит.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто - сыпь, зуд;\u003Cbr\u003Eредко - крапивница;\u003Cbr\u003Eочень редко - ангионевротический отек, стойкая лекарственная эритема;\u003Cbr\u003Eчастота неизвестна - острый генерализованный экзантематозный пустулез.\u003Cbr\u003EНарушения со стороны мышечной, скелетной и соединительной ткани:\u003Cbr\u003Eчастота неизвестна - артралгия.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eочень редко - дизурия, энурез;\u003Cbr\u003Eчастота неизвестна - задержка мочи.\u003Cbr\u003EОбщие нарушения и реакции в месте введения:\u003Cbr\u003Eнечасто - астения, недомогание;\u003Cbr\u003Eредко - периферические отеки.\u003Cbr\u003EОписание отдельных нежелательных реакций\u003Cbr\u003EПосле прекращения применения цетиризина были отмечены случаи зуда, в том числе интенсивного зуда и/или крапивницы.\u003Cbr\u003EЕсли у Вас отмечаются побочные эффекты, указанные в инструкции, или они усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Цетиризин является метаболитом гидроксизина, относится к группе конкурентных антагонистов гистамина и блокирует H1-гистаминовые рецепторы.\u003Cbr\u003EВ дополнение к антигистаминному эффекту цетиризин предупреждает развитие и облегчает течение аллергических реакций: в дозе 10 мг один или два раза в день ингибирует позднюю фазу агрегации эозинофилов в коже и конъюнктиве пациентов, подверженных атопии.\u003Cbr\u003EКлиническая эффективность и безопасность\u003Cbr\u003EИсследования на здоровых добровольцах показали, что цетиризин в дозах 5 или 10 мг значительно ингибирует реакцию в виде сыпи и покраснения на введение в кожу гистамина в высокой концентрации, однако корреляция с эффективностью не установлена. В 6-недельном плацебо-контролируемом исследовании с участием 186 пациентов с аллергическим ринитом и сопутствующей бронхиальной астмой легкого и среднетяжелого течения показано, что прием цетиризина в дозе 10 мг один раз в сутки уменьшает симптомы ринита и не влияет на функцию легких.\u003Cbr\u003EРезультаты данного исследования подтверждают безопасность применения цетиризина у пациентов, страдающих аллергией и бронхиальной астмой легкого и среднетяжелого течения.\u003Cbr\u003EВ плацебо-контролируемом исследовании показано, что прием цетиризина в дозе 60 мг в сутки в течение 7 дней не вызывал клинически значимого удлинения интервала QT.\u003Cbr\u003EПрием цетиризина в рекомендуемой дозе показал улучшение качества жизни пациентов с круглогодичным и сезонным аллергическим ринитами.\u003Cbr\u003EДети\u003Cbr\u003EВ 35-дневном исследовании с участием пациентов в возрасте 5-12 лет не выявлено признаков невосприимчивости к антигистаминному эффекту цетиризина. Нормальная реакция кожи на гистамин восстанавливалась в течение трех дней после отмены цетиризина при его неоднократном применении.\u003Cbr\u003EВ 7-дневном плацебо-контролируемом исследовании цетиризина в лекарственной форме \"сироп\" с участием 42 пациентов в возрасте от 6 до 11 месяцев продемонстрирована безопасность его применения. Цетиризин назначался в дозе 0,25 мг/кг два раза в день, что приблизительно соответствовало 4,5 мг в день (диапазон доз составлял от 3,4 до 6,2 мг в день).\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем."},{"name":"Фармакологическая группа","value":"противоаллергическое средство - H1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"капли для приема внутрь"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 6 месяцев"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте.\u003Cbr\u003EОткрытый флакон хранить не более 6 месяцев."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003EПосле однократного приема цетиризина в дозе 50 мг наблюдались следующие симптомы: спутанность сознания, головокружение, сонливость, ступор, слабость, беспокойство, седативный эффект, повышенная утомляемость, головная боль, мидриаз, зуд, тахикардия, тремор, задержка мочи, диарея, недомогание.\u003Cbr\u003EЛечение\u003Cbr\u003EНемедленно после приема препарата - промывание желудка или стимуляция рвоты. Рекомендуется прием активированного угля, проведение симптоматической и поддерживающей терапии. Специфического антидота нет. Гемодиализ неэффективен."},{"name":"Применение при беременности и кормлении грудью","value":"При анализе проспективных данных более чем 700 случаев исходов беременности не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью.\u003Cbr\u003EЭкспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и постнатальное развитие.\u003Cbr\u003EАдекватных и строго контролируемых клинических исследований по безопасности применения цетиризина у беременных женщин не проводилось, поэтому препарат противопоказан при беременности.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EНе следует применять препарат в период грудного вскармливания, так как цетиризин экскретируется с грудным молоком.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии цетиризина на фертильность человека ограничены, однако отрицательного влияния на фертильность не выявлено."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При объективной оценке способности к вождению автотранспорта и управлению механизмами достоверно не выявлено каких-либо нежелательных явлений при приеме цетиризина в рекомендуемой дозе. Однако пациентам с проявлениями сонливости на фоне приема препарата целесообразно воздерживаться от управления автомобилем, занятий потенциально опасными видами деятельности или управления механизмами, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Ввиду потенциального угнетающего влияния на ЦНС следует соблюдать осторожность при назначении цетиризина детям в возрасте до 1 года при наличии следующих ограничивающих факторов риска возникновения синдрома внезапной детской смерти, таких, как (но не ограничиваясь этим списком):\u003Cbr\u003E- синдром апноэ во сне или синдром внезапной детской смерти детей грудного возраста у брата или сестры;\u003Cbr\u003E- злоупотребление матери наркотиками или курением во время беременности;\u003Cbr\u003E- молодой возраст матери (19 лет и моложе);\u003Cbr\u003E- злоупотребление курением няни, ухаживающей за ребенком (одна пачка сигарет в день или более);\u003Cbr\u003E- дети, регулярно засыпающие лицом вниз и которых не укладывают на спину;\u003Cbr\u003E- недоношенные (менее 37 недель гестации) или рожденные с недостаточной массой тела (ниже 10-го перцентиля от гестационного возраста) дети;\u003Cbr\u003E- при совместном приеме препаратов, оказывающих угнетающее влияние на ЦНС.\u003Cbr\u003EУ пациентов с повреждениями спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов к задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи. Рекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем.\u003Cbr\u003EОсторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что Н1-гистаминовых рецепторов блокаторы ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EПосле прекращения применения цетиризина может появиться зуд и/или крапивница, даже если эти симптомы отсутствовали в начале лечения. В некоторых случаях симптомы могут быть интенсивными и требовать возобновления приема цетиризина. Симптомы исчезают при возобновлении приема цетиризина."},{"name":"Взаимодействие","value":"Одновременное применение с азитромицином, циметидином, эритромицином, кетоконазолом или псевдоэфедрином не влияет на фармакокинетические параметры цетиризина. Фармакокинетических взаимодействий не наблюдалось.\u003Cbr\u003EСогласно испытаниям in vitro, цетиризин не влияет на эффект связывания варфарина с белками.\u003Cbr\u003EОдновременный прием азитромицина, эритромицина, кетоконазола, теофиллина и псевдоэфедрина не выявил существенных изменений в клинических лабораторных показателях, жизненно важных функциях и ЭКГ.\u003Cbr\u003EВ исследовании с одновременным приемом теофиллина (400 мг в день) и цетиризина (20 мг в день) было обнаружено незначительное, но статистически достоверное, повышение 24-часовой AUC (площади под кривой) на 19% для цетиризина и на 11% для теофиллина. Кроме того, максимальные уровни в плазме крови увеличились до 7,7% и 6,4% соответственно для цетиризина и теофиллина. Одновременно клиренс цетиризина уменьшился на -16%, а также на -10% в случае теофиллина, когда цетиризин принимали пациенты, которые ранее получали лечение теофиллином. Тем не менее предварительное лечение цетиризином не оказало существенного влияния на фармакокинетические параметры теофиллина.\u003Cbr\u003EПосле однократного приема цетиризина в дозе 10 мг эффект алкоголя (0,8%) значительно не усиливался; статистически значимое взаимодействие с 5 мг диазепама было доказано в одном из 16 психометрических тестов.\u003Cbr\u003EОдновременный прием 10 мг цетиризина в день с глипизидом привел к незначительному снижению показателей глюкозы. Этот эффект не имеет клинического значения. Тем не менее рекомендуется раздельный прием - глипизид утром и цетиризин вечером.\u003Cbr\u003EЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные), перед применением препарата проконсультируйтесь с врачом."},{"name":"Регистрационный номер","value":"ЛП-005501"},{"name":"Дата государственной регистрации","value":"29.04.2019"},{"name":"Владелец регистрационного удостоверения","value":"Вертекс"},{"name":"Изготовитель","value":"Вертекс"},{"name":"Фасовщик","value":"Вертекс"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Цетиризин-Вертекс"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_8976989795005151561"}}}}
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    Цена с картой Яндекс Пэй 157 ₽ вместо 159
    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  • Цетрин таб. п/о плен., 10 мг, 20 шт.
    –1 %
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    Цетрин таб. п/о плен., 10 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 146 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 160 ₽ вместо 162
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таб. п/о плен., 10 мг, 20 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  • Зиртек капли д/вн. приема, 10 мг/мл, 20 мл
    –1 %
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    Зиртек капли д/вн. приема, 10 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 36 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 172 ₽ вместо 174
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  • Цетиризин капли д/вн. приема, 10 мг/мл, 10 мл
    –1 %
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    Цетиризин капли д/вн. приема, 10 мг/мл, 10 мл

    Рейтинг товара: 4.2 из 5
    на основе 10 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 105 ₽ вместо 106
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  • Цетиризин таб. п/о плен., 10 мг, 10 шт.
    –2 %
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    Цетиризин таб. п/о плен., 10 мг, 10 шт.

    Рейтинг товара: 4.9 из 5
    на основе 24 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 57 ₽ вместо 58
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  • Цетиризин капли д/вн. приема, 10 мг/мл, 20 мл
    –1 %
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    Цетиризин капли д/вн. приема, 10 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 6 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 196 ₽ вместо 198
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  • Фенистил капли д/вн. приема, 0.1%, 20 мл
    –1 %
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    Фенистил капли д/вн. приема, 0.1%, 20 мл

    Рейтинг товара: 4.8 из 5
    на основе 20 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 577 ₽ вместо 583
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  • Солонэкс капли д/вн. приема, 10 мг/мл, 20 мл
    –1 %
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    Солонэкс капли д/вн. приема, 10 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 184 ₽ вместо 186
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  • Цетиризин капли д/вн. приема, 10 мг/мл, 20 мл
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    Цетиризин капли д/вн. приема, 10 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 183 ₽
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  • Цетиризин таб., 10 мг, 10 шт.
    –14 %
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    Цетиризин таб., 10 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 49 ₽ вместо 57
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  • Супрастинекс капли д/вн. приема фл., 5 мг/мл, 20 мл
    –1 %
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    Супрастинекс капли д/вн. приема фл., 5 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 414 ₽ вместо 418
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Инструкция

Показания к применению

Взрослым, детям с 6 месяцев и старше для облегчения:
- назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита, таких как зуд, чихание, заложенность носа, ринорея, слезотечение, гиперемия конъюнктивы;
- симптомов хронической идиопатической крапивницы.
Применение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем.

Противопоказания

Повышенная чувствительность к цетиризину, гидроксизину или приоизводным пиперазина, а также к другим компонентам препарата;
- терминальная стадия почечной недостаточности (КК < 10 мл/мин);
- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности);
- беременность.

Способ применения и дозы

Внутрь, накапать в ложку или растворить в воде.
Количество воды для растворения препарата должно соответствовать количеству жидкости, которое пациент (особенно ребенок) в состоянии проглотить.
Раствор следует принимать сразу после приготовления.
Взрослые
10 мг (20 капель) 1 раз в день.
Если через три дня после начала лечения улучшения не наступает, или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом.
Применяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции.
Применение у особых групп пациентов
Пациенты пожилого возраста
Нет необходимости в снижении дозы у пожилых пациентов, если функция почек не нарушена.
Пациенты с почечной недостаточностью
Поскольку цетиризин выводится из организма в основном почками (см. подраздел "Фармакокинетика"), при невозможности альтернативного лечения пациентам с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины КК). Пациенты с нарушением функции печени
Пациентам с нарушением только функции печени коррекции режима дозирования не требуется.
Пациенты с сочетанием почечной и печеночной недостаточности
Рекомендуется коррекция дозирования (см. таблицу выше).
Дети
Применение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем.
Дети от 6 месяцев до 12 месяцев
2,5 мг (5 капель) 1 раз в день.
Дети от 1 года до 6 лет
2,5 мг (5 капель) 2 раза в день.
Дети от 6 до 12 лет
5 мг (10 капель) 2 раза в день.
Дети старше 12 лет
10 мг (20 капель) 1 раз в день.
Иногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.
Детям с почечной недостаточностью дозу корректируют с учетом КК и массы тела.
Полная инструкция
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Цетиризин-Вертекс капли д/вн. приема
Цетиризин-Вертекс капли д/вн. приема, 10 мг/мл, 20 мл
5.0
(9)
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1 вопрос
Инструкция

Цена с картой Яндекс Пэй:174 ₽

Скидка: 1%
–1 %
Вместо: 176 ₽
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5.0
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У продавца:9 оценок·2 отзыва
У всех продавцов:13 оценок·4 отзыва
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user avatar
Год назад • Юлия Новикова • Куплен на Маркете
Достоинства: У сына аллергия. С нашей проблемой справляется на ура. Заказываем уже не первый бутылек.
Недостатки: Их нет
user avatar
3 месяца назад • Елена К. • Куплен на Маркете
Достоинства: Все согласно инструкции, с задачей справляется.
Недостатки: Их нет
Комментарий: Спасибо за быструю доставку.
Посмотреть все отзывы на Маркете
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