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Описание

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Ципролет А таб. п/о плен., 500 мг+600 мг, 10 шт.

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Коротко о товаре

Артикул Маркета
3123197802
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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применению","value":"Смешанные бактериальные инфекции, вызванные чувствительными грамположительными и грамотрицательными микроорганизмами, в ассоциации с анаэробными микроорганизмами и/или простейшими:\u003Cbr\u003Eинфекции дыхательных путей (острый и хронический (в стадии обострения) бронхит, пневмония, бронхоэктатическая болезнь);\u003Cbr\u003Eинфекции ЛОР-органов (средний отит, гайморит, фронтит, синусит, мастоидит, тонзиллит, фарингит);\u003Cbr\u003Eинфекции ротовой полости (острый язвенный гингивит, периодонтит, периостит).\u003Cbr\u003Eинфекции почек и мочевыводящих путей (цистит, пиелонефрит);\u003Cbr\u003Eинфекции органов малого таза и половых органов (простатит, аднексит, сальпингит, оофорит, эндометрит, тубулярный абсцесс, пельвиоперитонит);\u003Cbr\u003Eинтраабдоминальные инфекции (инфекции желудочно-кишечного тракта, желчных путей, внутрибрюшинные абсцессы);\u003Cbr\u003Eинфекции кожи и мягких тканей (инфицированные язвы, раны, ожоги, абсцессы, флегмона, язвенные поражения кожи при \"синдроме диабетической стопы\", пролежни);\u003Cbr\u003Eинфекции костей и суставов (остеомиелит, септический артрит);\u003Cbr\u003Eпослеоперационные инфекции."},{"name":"Противопоказания","value":"Гиперчувствительность (в том числе, к производным фторхинолона или имидазола), заболевания крови (в анамнезе), угнетение костномозгового кроветворения, органические заболевания центральной нервной системы, беременность, период лактации, одновременный прием с тизанидином (риск выраженного снижения артериального давления, сонливости), острая порфирия, детский возраст до 18 лет."},{"name":"Состав","value":"Каждая таблетка содержит:\u003Cbr\u003EДействующие вещества: ципрофлоксацина гидрохлорид моногидрат (эквивалентно 500 мг ципрофлоксацина) - 582,285 мг и тинидазол - 600,000 мг; Вспомогательные вещества: крахмал кукурузный 35 мг, кроскармеллоза натрия 27,476 мг, целлюлоза микрокристаллическая 20,33 мг, карбоксиметилкрахмал натрия (тип А) 5 мг, кремния диоксид коллоидный 3,952 мг, тальк 8,952 мг, магния стеарат 7 мг; состав оболочки:\u003Cbr\u003EОпадрай белый 40 мг\u003Cbr\u003E(гипромеллоза 55,46 %, тальк 19,84 %, титана диоксид 11,93 %, макрогол-6000 11,09 %, полисорбат-80 0,84 %, сорбиновая кислота 0,84 %)."},{"name":"Действующее вещество","value":"Тинидазол+Ципрофлоксацин","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:36090258"]}}},{"name":"Способ применения и дозы","value":"Внутрь, за 1 час до еды или через 2 часа после еды, запивая достаточным количеством воды. Не следует разламывать, разжевывать или разрушать таблетку.\u003Cbr\u003EРекомендуемая доза - 1 таблетка 2 раза в день в течение 5-10 дней."},{"name":"Побочные действия","value":"Со стороны пищеварительной системы: снижение аппетита, сухость слизистой оболочки полости рта, \"металлический\" привкус во рту, тошнота, рвота, диарея, боль в животе, метеоризм, холестатическая желтуха (особенно у пациентов с перенесенными заболеваниями печени), гепатит, гепатонекроз.\u003Cbr\u003EСо стороны нервной системы: головная боль, головокружение, повышенная утомляемость, нарушения координации движений (в том числе локомоторная атаксия), дизартрия, периферическая невропатия, редко - судороги, слабость, тревожность, тремор, бессонница, “кошмарные” сновидения, периферическая паралгезия (аномалия восприятия чувства боли), повышение внутричерепного давления, спутанность сознания, депрессия, галлюцинации, а также другие проявления психотических реакций, мигрень, обморочные состояния, тромбоз церебральных артерий, повышенное потоотделение.\u003Cbr\u003EСо стороны органов чувств: нарушения вкуса и обоняния, нарушение зрения (диплопия, изменение цветовосприятия), шум в ушах, снижение слуха.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: тахикардия, аритмия, снижение артериального давления.\u003Cbr\u003EСо стороны органов кроветворения: лейкопения, гранулоцитопения, анемия (в том числе гемолитическая), тромбоцитопения, лейкоцитоз, тромбоцитоз.\u003Cbr\u003EСо стороны мочевыделительной системы: гематурия, кристаллурия (при щелочной реакции мочи и снижении диуреза), гломерулонефрит, дизурия, полиурия, задержка мочи, альбуминурия, снижение азотвыделительной функции почек, интерстициальный нефрит. Аллергические реакции: кожный зуд, крапивница, кожная сыпь, лекарственная лихорадка, петехии, ангионевротический отек, одышка, эозинофилия, фотосенсибилизация, васкулит, узловатая эритема, мультиформная экссудативная эритема (в том числе синдром Стивенса- Джонсона), токсический эпидермальный некролиз (синдром Лайелла).\u003Cbr\u003EСо стороны лабораторных показателей: гипопротромбинемия, повышение активности \"печеночных\" трансаминаз и щелочной фосфатазы, гиперкреатининемия, гипербилирубинемия, гипергликемия.\u003Cbr\u003EПрочие: артралгия, артрит, тендовагинит, разрывы сухожилий, астения, миалгия,\u003Cbr\u003Eсуперинфекции (кандидоз, псевдомембранозный колит), \"приливы\" крови к лицу."},{"name":"Фармакологическое действие","value":"Комбинированный препарат, действие которого обусловлено компонентами, входящими в его состав.\u003Cbr\u003EТинидазол - противопротозойное и противомикробное средство, производное имидазола, эффективен в отношении Trichomonas vaginalis, Entamoeba histolitica, Lamblia, а также возбудителей анаэробных инфекций (Clostridium spp., Bacteroides fragilis, Bacteroides melaninogenicus, Eubacter spp., Fusobacterium spp., Peptococcus spp. и Peptostreptococcus spp ). Являясь высоколипофильным препаратом, проникает внутрь трихомонад и анаэробных микроорганизмов, где восстанавливается нитроредуктазой, угнетает синтез и повреждает структуру ДНК.\u003Cbr\u003EЦипрофлоксацин - противомикробное средство широкого спектра действия, производное фторхинолона, подавляет бактериальную ДНК-гиразу (топоизомеразы II и IV, ответственные за процесс суперспирализации хромосомной ДНК вокруг ядерной РНК, что необходимо для считывания генетической информации), нарушает синтез ДНК, рост и деление бактерий; вызывает выраженные морфологические изменения (в том числе, клеточной стенки и мембран) и быструю гибель бактериальной клетки.\u003Cbr\u003EДействует бактерицидно на грамотрицательные организмы в период покоя и деления (поскольку влияет не только на ДНК-гиразу, но и вызывает лизис клеточной стенки), на грамположительные микроорганизмы - только в период деления. Низкая токсичность для клеток макроорганизма объясняется отсутствием в них ДНК-гиразы. На фоне приема\u003Cbr\u003E, ципрофлоксацина не происходит параллельной выработки устойчивости к другим антибиотикам, не принадлежащим к группе ингибиторов гиразы, что делает его высокоэффективным по отношению к бактериям, устойчивым к аминогликозидам, пенициллинам, цефалоспоринам, тетрациклинам и многим другим антибиотикам.\u003Cbr\u003EК ципрофлоксацину чувствительны грамотрицательные аэробные бактерии: энтеробактерии {Escherichia coli, Salmonella spp., Shigella spp., Citrobacter spp., Klebsiella spp., Enterobacter spp., Proteus mirabilis, Proteus vulgaris, Serratia marcescens, Hafnia alvei, Edwardsiella tarda, Providencia spp., Morganella morganii, Vibrio spp., Yersinia spp.), другие грамотрицательные бактерии {Haemophilus spp., Pseudomonas aeruginosa, Moraxella catarrhalis, Aeromonas spp., Pasteurella multocida, Plesiomonas shigelloides, Campylobacter jejuni, Neisseria spp.), некоторые внутриклеточные возбудители - Legionella pneumophila, Brucella spp., Listeria monocytogenes, Mycobacterium tuberculosis, Mycobacterium kansasii; грамположительные аэробные бактерии: Staphylococcus spp. {Staphylococcus aureus, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus saprophyticus), Streptococcus spp. {Streptococcus pyogenes, Streptococcus agalactiae).\u003Cbr\u003EБольшинство стафилококков, устойчивых к метициллину, резистентны и к ципрофлоксацину. Резистентность развивается крайне медленно, поскольку, с одной стороны, после действия ципрофлоксацина практически не остается персистирующих микроорганизмов, а с другой - у бактериальных клеток нет ферментов его инактивирующих. К препарату резистентны: Bacteroides fragilis, Pseudomonas cepacia, Pseudomonas maltophilia, Ureaplasma urealyticum, Clostridium difficile, Nocardia asteroides. He эффективен в отношении Treponema pallidum."},{"name":"Фармакологическая группа","value":"противомикробное средство комбинированное"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В сухом, защищенном от света месте, при температуре не выше 25°С.\u003Cbr\u003EХранить в недоступном для детей месте!"},{"name":"Передозировка","value":"Симптомы: в случаях острой передозировки превалирующими будут симптомы обратимого поражения мочевыделительной системы, возможны судороги.\u003Cbr\u003EЛечение: индукция рвоты, промывание желудка. Симптоматическая, поддерживающая терапия (в том числе адекватная гидратация организма). Специфического антидота нет. С помощью гемо- или перитонеального диализа тинидазол может быть полностью выведен из организма, а ципрофлоксацин - незначительно (менее 10%)."},{"name":"Применение при беременности и кормлении грудью","value":"Поскольку тинидазол и ципрофлоксацин экскретируются в грудное молоко, то на период лечения препаратом необходимо прекратить кормление грудью, поскольку тинидазол может оказывать мутагенное и канцерогенное действие."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние на способность к вождению автотранспорта и управлению механизмами. Во время лечения следует воздержаться от занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Следует учитывать возможность возникновения перекрестных аллергических реакций. У пациентов с гиперчувствительностью к другим производным имидазола может развиться перекрестная чувствительность и на тинидазол; развитие перекрестной аллергической реакции на ципрофлоксацин возможно также и у больных с гиперчувствительностью к другим производным фторхинолонов.\u003Cbr\u003EВо время лечения рекомендуется избегать контакта с прямыми солнечными лучами. При возникновении реакций фотосенсибилизации следует немедленно прекратить применение препарата.\u003Cbr\u003EВ период лечения не рекомендуется принимать этанол (риск развития дисульфирамоподобных реакций на фоне тинидазола, входящего в состав препарата).\u003Cbr\u003EВо избежание развития кристаллурии нельзя превышать рекомендованную суточную дозу, необходимо также достаточное потребление жидкости и поддержание кислой реакции мочи. Вызывает темное окрашивание мочи, что не имеет клинического значения.\u003Cbr\u003EБольным с эпилепсией, судорогами в анамнезе, сосудистыми заболеваниями и органическими поражениями мозга, в связи с угрозой развития побочных реакций со стороны центральной нервной системы, препарат следует назначать только по \"жизненным\" показаниям.\u003Cbr\u003E^ При возникновении во время или после лечения тяжелой и длительной диареи следует исключить диагноз псевдомембранозного колита, который требует немедленной отмены препарата и назначения соответствующего лечения.\u003Cbr\u003EПри появлении болей в сухожилиях или при проявлении первых признаков тендовагинита лечение следует прекратить.\u003Cbr\u003EПри лечении более 6 дней следует контролировать картину периферической крови."},{"name":"Взаимодействие","value":"Эффекты, обусловленные тинидазолом. Усиливает эффект непрямых антикоагулянтов. Для уменьшения риска развития кровотечений дозу препарата Ципролет А снижают на 50%. Усиливает действие этанола (дисульфирамоподобные реакции). Фенобарбитал ускоряет метаболизм тинидазола. Препарат Ципролет А не рекомендуется назначать с этионамидом. Эффекты, обусловленные ципрофлоксацином. Вследствие снижения активности процессов микросомального окисления в гепатоцитах повышает концентрацию и удлиняет Тш теофиллина и других ксантинов, в том числе кофеина, пероральных гипогликемических лекарственных средств, непрямых антикоагулянтов, способствует снижению протромбинового\u003Cbr\u003E. индекса. Усиливает нефротоксическое действие циклоспорина, отмечается увеличение сывороточного креатинина, у таких пациентов необходим контроль этого показателя 2 раза в неделю. Пероральный прием совместно с Fe-содержащими лекарственными средствами, сукральфатом и антацидными лекарственными средствами, содержащими Mg2+, Са2+, А13+, диданозином приводит к снижению всасывания ципрофлоксацина. Поэтому препарат Ципролет®А назначается за 1-2 ч до или через 4 ч после приема выше указанных лекарственных средств. Нестероидные противовоспалительные препараты (исключая ацетилсалициловую кислоту) повышают риск развития судорог. Метоклопрамид ускоряет абсорбцию, что приводит к уменьшению ТCmaxах- Совместное назначение урикозурических лекарственных средств приводит к замедлению выведения (до 50%) и повышению плазменной концентрации ципрофлоксацина. Повышает Сmах в 7 раз (от 4 до 21 раза) и AUC (площадь под фармакокинетической кривой) тизанидина, что повышает риск выраженного снижения артериального давления и сонливости.\u003Cbr\u003EПрепарат Ципролет А совместим с сульфаниламидами и антибиотиками (бета-лактамные антибиотики, аминогликозиды, эритромицин, рифампицин, цефалоспорины), при сочетании с которыми, обычно, наблюдается синергизм."},{"name":"Регистрационный номер","value":"ЛCP-002404/10"},{"name":"Дата государственной регистрации","value":"21.12.2017"},{"name":"Владелец регистрационного удостоверения","value":"Dr. Reddy's Laboratories","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["34324371:35649313","7893318:16077120"]}}},{"name":"Изготовитель","value":"Dr. Reddy's"},{"name":"Фасовщик","value":"Dr. Reddy's"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Ципролет","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["17796364:18036844"]}}},{"name":"Срок годности","value":"35 мес."}]}},"fullSpecsGrouped":{"16809545912869936516":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Назначение","value":"аднексит, бронхит, гайморит, гингивит, инфекции кожи и мягких тканей, инфицированные раны и нарывы, остеомиелит, периодонтит, пиелонефрит, пневмония, простатит, синусит, средний отит, тонзиллит, фарингит, цистит, эндометрит"},{"name":"Органы и системы","value":"дыхательная система, кожа, костная система, носовая полость, половая система, почки, ротовая полость"},{"name":"Показания к применению","value":"Смешанные бактериальные инфекции, вызванные чувствительными грамположительными и грамотрицательными микроорганизмами, в ассоциации с анаэробными микроорганизмами и/или простейшими:\u003Cbr\u003Eинфекции дыхательных путей (острый и хронический (в стадии обострения) бронхит, пневмония, бронхоэктатическая болезнь);\u003Cbr\u003Eинфекции ЛОР-органов (средний отит, гайморит, фронтит, синусит, мастоидит, тонзиллит, фарингит);\u003Cbr\u003Eинфекции ротовой полости (острый язвенный гингивит, периодонтит, периостит).\u003Cbr\u003Eинфекции почек и мочевыводящих путей (цистит, пиелонефрит);\u003Cbr\u003Eинфекции органов малого таза и половых органов (простатит, аднексит, сальпингит, оофорит, эндометрит, тубулярный абсцесс, пельвиоперитонит);\u003Cbr\u003Eинтраабдоминальные инфекции (инфекции желудочно-кишечного тракта, желчных путей, внутрибрюшинные абсцессы);\u003Cbr\u003Eинфекции кожи и мягких тканей (инфицированные язвы, раны, ожоги, абсцессы, флегмона, язвенные поражения кожи при \"синдроме диабетической стопы\", пролежни);\u003Cbr\u003Eинфекции костей и суставов (остеомиелит, септический артрит);\u003Cbr\u003Eпослеоперационные инфекции."},{"name":"Противопоказания","value":"Гиперчувствительность (в том числе, к производным фторхинолона или имидазола), заболевания крови (в анамнезе), угнетение костномозгового кроветворения, органические заболевания центральной нервной системы, беременность, период лактации, одновременный прием с тизанидином (риск выраженного снижения артериального давления, сонливости), острая порфирия, детский возраст до 18 лет."},{"name":"Состав","value":"Каждая таблетка содержит:\u003Cbr\u003EДействующие вещества: ципрофлоксацина гидрохлорид моногидрат (эквивалентно 500 мг ципрофлоксацина) - 582,285 мг и тинидазол - 600,000 мг; Вспомогательные вещества: крахмал кукурузный 35 мг, кроскармеллоза натрия 27,476 мг, целлюлоза микрокристаллическая 20,33 мг, карбоксиметилкрахмал натрия (тип А) 5 мг, кремния диоксид коллоидный 3,952 мг, тальк 8,952 мг, магния стеарат 7 мг; состав оболочки:\u003Cbr\u003EОпадрай белый 40 мг\u003Cbr\u003E(гипромеллоза 55,46 %, тальк 19,84 %, титана диоксид 11,93 %, макрогол-6000 11,09 %, полисорбат-80 0,84 %, сорбиновая кислота 0,84 %)."},{"name":"Действующее вещество","value":"Тинидазол+Ципрофлоксацин"},{"name":"Способ применения и дозы","value":"Внутрь, за 1 час до еды или через 2 часа после еды, запивая достаточным количеством воды. Не следует разламывать, разжевывать или разрушать таблетку.\u003Cbr\u003EРекомендуемая доза - 1 таблетка 2 раза в день в течение 5-10 дней."},{"name":"Побочные действия","value":"Со стороны пищеварительной системы: снижение аппетита, сухость слизистой оболочки полости рта, \"металлический\" привкус во рту, тошнота, рвота, диарея, боль в животе, метеоризм, холестатическая желтуха (особенно у пациентов с перенесенными заболеваниями печени), гепатит, гепатонекроз.\u003Cbr\u003EСо стороны нервной системы: головная боль, головокружение, повышенная утомляемость, нарушения координации движений (в том числе локомоторная атаксия), дизартрия, периферическая невропатия, редко - судороги, слабость, тревожность, тремор, бессонница, “кошмарные” сновидения, периферическая паралгезия (аномалия восприятия чувства боли), повышение внутричерепного давления, спутанность сознания, депрессия, галлюцинации, а также другие проявления психотических реакций, мигрень, обморочные состояния, тромбоз церебральных артерий, повышенное потоотделение.\u003Cbr\u003EСо стороны органов чувств: нарушения вкуса и обоняния, нарушение зрения (диплопия, изменение цветовосприятия), шум в ушах, снижение слуха.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: тахикардия, аритмия, снижение артериального давления.\u003Cbr\u003EСо стороны органов кроветворения: лейкопения, гранулоцитопения, анемия (в том числе гемолитическая), тромбоцитопения, лейкоцитоз, тромбоцитоз.\u003Cbr\u003EСо стороны мочевыделительной системы: гематурия, кристаллурия (при щелочной реакции мочи и снижении диуреза), гломерулонефрит, дизурия, полиурия, задержка мочи, альбуминурия, снижение азотвыделительной функции почек, интерстициальный нефрит. Аллергические реакции: кожный зуд, крапивница, кожная сыпь, лекарственная лихорадка, петехии, ангионевротический отек, одышка, эозинофилия, фотосенсибилизация, васкулит, узловатая эритема, мультиформная экссудативная эритема (в том числе синдром Стивенса- Джонсона), токсический эпидермальный некролиз (синдром Лайелла).\u003Cbr\u003EСо стороны лабораторных показателей: гипопротромбинемия, повышение активности \"печеночных\" трансаминаз и щелочной фосфатазы, гиперкреатининемия, гипербилирубинемия, гипергликемия.\u003Cbr\u003EПрочие: артралгия, артрит, тендовагинит, разрывы сухожилий, астения, миалгия,\u003Cbr\u003Eсуперинфекции (кандидоз, псевдомембранозный колит), \"приливы\" крови к лицу."},{"name":"Фармакологическое действие","value":"Комбинированный препарат, действие которого обусловлено компонентами, входящими в его состав.\u003Cbr\u003EТинидазол - противопротозойное и противомикробное средство, производное имидазола, эффективен в отношении Trichomonas vaginalis, Entamoeba histolitica, Lamblia, а также возбудителей анаэробных инфекций (Clostridium spp., Bacteroides fragilis, Bacteroides melaninogenicus, Eubacter spp., Fusobacterium spp., Peptococcus spp. и Peptostreptococcus spp ). Являясь высоколипофильным препаратом, проникает внутрь трихомонад и анаэробных микроорганизмов, где восстанавливается нитроредуктазой, угнетает синтез и повреждает структуру ДНК.\u003Cbr\u003EЦипрофлоксацин - противомикробное средство широкого спектра действия, производное фторхинолона, подавляет бактериальную ДНК-гиразу (топоизомеразы II и IV, ответственные за процесс суперспирализации хромосомной ДНК вокруг ядерной РНК, что необходимо для считывания генетической информации), нарушает синтез ДНК, рост и деление бактерий; вызывает выраженные морфологические изменения (в том числе, клеточной стенки и мембран) и быструю гибель бактериальной клетки.\u003Cbr\u003EДействует бактерицидно на грамотрицательные организмы в период покоя и деления (поскольку влияет не только на ДНК-гиразу, но и вызывает лизис клеточной стенки), на грамположительные микроорганизмы - только в период деления. Низкая токсичность для клеток макроорганизма объясняется отсутствием в них ДНК-гиразы. На фоне приема\u003Cbr\u003E, ципрофлоксацина не происходит параллельной выработки устойчивости к другим антибиотикам, не принадлежащим к группе ингибиторов гиразы, что делает его высокоэффективным по отношению к бактериям, устойчивым к аминогликозидам, пенициллинам, цефалоспоринам, тетрациклинам и многим другим антибиотикам.\u003Cbr\u003EК ципрофлоксацину чувствительны грамотрицательные аэробные бактерии: энтеробактерии {Escherichia coli, Salmonella spp., Shigella spp., Citrobacter spp., Klebsiella spp., Enterobacter spp., Proteus mirabilis, Proteus vulgaris, Serratia marcescens, Hafnia alvei, Edwardsiella tarda, Providencia spp., Morganella morganii, Vibrio spp., Yersinia spp.), другие грамотрицательные бактерии {Haemophilus spp., Pseudomonas aeruginosa, Moraxella catarrhalis, Aeromonas spp., Pasteurella multocida, Plesiomonas shigelloides, Campylobacter jejuni, Neisseria spp.), некоторые внутриклеточные возбудители - Legionella pneumophila, Brucella spp., Listeria monocytogenes, Mycobacterium tuberculosis, Mycobacterium kansasii; грамположительные аэробные бактерии: Staphylococcus spp. {Staphylococcus aureus, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus saprophyticus), Streptococcus spp. {Streptococcus pyogenes, Streptococcus agalactiae).\u003Cbr\u003EБольшинство стафилококков, устойчивых к метициллину, резистентны и к ципрофлоксацину. Резистентность развивается крайне медленно, поскольку, с одной стороны, после действия ципрофлоксацина практически не остается персистирующих микроорганизмов, а с другой - у бактериальных клеток нет ферментов его инактивирующих. К препарату резистентны: Bacteroides fragilis, Pseudomonas cepacia, Pseudomonas maltophilia, Ureaplasma urealyticum, Clostridium difficile, Nocardia asteroides. He эффективен в отношении Treponema pallidum."},{"name":"Фармакологическая группа","value":"противомикробное средство комбинированное"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В сухом, защищенном от света месте, при температуре не выше 25°С.\u003Cbr\u003EХранить в недоступном для детей месте!"},{"name":"Передозировка","value":"Симптомы: в случаях острой передозировки превалирующими будут симптомы обратимого поражения мочевыделительной системы, возможны судороги.\u003Cbr\u003EЛечение: индукция рвоты, промывание желудка. Симптоматическая, поддерживающая терапия (в том числе адекватная гидратация организма). Специфического антидота нет. С помощью гемо- или перитонеального диализа тинидазол может быть полностью выведен из организма, а ципрофлоксацин - незначительно (менее 10%)."},{"name":"Применение при беременности и кормлении грудью","value":"Поскольку тинидазол и ципрофлоксацин экскретируются в грудное молоко, то на период лечения препаратом необходимо прекратить кормление грудью, поскольку тинидазол может оказывать мутагенное и канцерогенное действие."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние на способность к вождению автотранспорта и управлению механизмами. Во время лечения следует воздержаться от занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Следует учитывать возможность возникновения перекрестных аллергических реакций. У пациентов с гиперчувствительностью к другим производным имидазола может развиться перекрестная чувствительность и на тинидазол; развитие перекрестной аллергической реакции на ципрофлоксацин возможно также и у больных с гиперчувствительностью к другим производным фторхинолонов.\u003Cbr\u003EВо время лечения рекомендуется избегать контакта с прямыми солнечными лучами. При возникновении реакций фотосенсибилизации следует немедленно прекратить применение препарата.\u003Cbr\u003EВ период лечения не рекомендуется принимать этанол (риск развития дисульфирамоподобных реакций на фоне тинидазола, входящего в состав препарата).\u003Cbr\u003EВо избежание развития кристаллурии нельзя превышать рекомендованную суточную дозу, необходимо также достаточное потребление жидкости и поддержание кислой реакции мочи. Вызывает темное окрашивание мочи, что не имеет клинического значения.\u003Cbr\u003EБольным с эпилепсией, судорогами в анамнезе, сосудистыми заболеваниями и органическими поражениями мозга, в связи с угрозой развития побочных реакций со стороны центральной нервной системы, препарат следует назначать только по \"жизненным\" показаниям.\u003Cbr\u003E^ При возникновении во время или после лечения тяжелой и длительной диареи следует исключить диагноз псевдомембранозного колита, который требует немедленной отмены препарата и назначения соответствующего лечения.\u003Cbr\u003EПри появлении болей в сухожилиях или при проявлении первых признаков тендовагинита лечение следует прекратить.\u003Cbr\u003EПри лечении более 6 дней следует контролировать картину периферической крови."},{"name":"Взаимодействие","value":"Эффекты, обусловленные тинидазолом. Усиливает эффект непрямых антикоагулянтов. Для уменьшения риска развития кровотечений дозу препарата Ципролет А снижают на 50%. Усиливает действие этанола (дисульфирамоподобные реакции). Фенобарбитал ускоряет метаболизм тинидазола. Препарат Ципролет А не рекомендуется назначать с этионамидом. Эффекты, обусловленные ципрофлоксацином. Вследствие снижения активности процессов микросомального окисления в гепатоцитах повышает концентрацию и удлиняет Тш теофиллина и других ксантинов, в том числе кофеина, пероральных гипогликемических лекарственных средств, непрямых антикоагулянтов, способствует снижению протромбинового\u003Cbr\u003E. индекса. Усиливает нефротоксическое действие циклоспорина, отмечается увеличение сывороточного креатинина, у таких пациентов необходим контроль этого показателя 2 раза в неделю. Пероральный прием совместно с Fe-содержащими лекарственными средствами, сукральфатом и антацидными лекарственными средствами, содержащими Mg2+, Са2+, А13+, диданозином приводит к снижению всасывания ципрофлоксацина. Поэтому препарат Ципролет®А назначается за 1-2 ч до или через 4 ч после приема выше указанных лекарственных средств. Нестероидные противовоспалительные препараты (исключая ацетилсалициловую кислоту) повышают риск развития судорог. Метоклопрамид ускоряет абсорбцию, что приводит к уменьшению ТCmaxах- Совместное назначение урикозурических лекарственных средств приводит к замедлению выведения (до 50%) и повышению плазменной концентрации ципрофлоксацина. Повышает Сmах в 7 раз (от 4 до 21 раза) и AUC (площадь под фармакокинетической кривой) тизанидина, что повышает риск выраженного снижения артериального давления и сонливости.\u003Cbr\u003EПрепарат Ципролет А совместим с сульфаниламидами и антибиотиками (бета-лактамные антибиотики, аминогликозиды, эритромицин, рифампицин, цефалоспорины), при сочетании с которыми, обычно, наблюдается синергизм."},{"name":"Регистрационный номер","value":"ЛCP-002404/10"},{"name":"Дата государственной регистрации","value":"21.12.2017"},{"name":"Владелец регистрационного удостоверения","value":"Dr. Reddy's Laboratories"},{"name":"Изготовитель","value":"Dr. Reddy's"},{"name":"Фасовщик","value":"Dr. Reddy's"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Ципролет"},{"name":"Срок годности","value":"35 мес."}]}],"transitionId":"tr_929808667596853600"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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371 ₽

  • Сегодня, самовывоз • 0 ₽
ЕАПТЕКА
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  • Ципролет таб. п/о плен., 500 мг, 10 шт.
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    Ципролет таб. п/о плен., 500 мг, 10 шт.

    Рейтинг товара: 4.9 из 5
    на основе 13 оценок
    Цена 113 ₽
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  • Ципрофлоксацин таб. п/о плен., 250 мг, 10 шт.
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    Ципрофлоксацин таб. п/о плен., 250 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 20 оценок
    Цена 44 ₽
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  • Ципролет таб. п.п/о, 250 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5fb12hoytnj/toggleWishlist":{"skuId":"101990663962","productId":1832462633,"offerId":"xdrd05NgD9RUJDmu9OX2xQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQmsee48an3+8mEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIqdLk6QYQmo74+PsCGLGLuggg99zBBw==","sign":"+Ct+x4EupaR0gh3+KsjCQnRFbPiofcBFhC/rEHaYtVA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5fb12hoytnj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ципролет таб. п.п/о, 250 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 5 оценок
    Цена 56 ₽
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  • Цифран СТ таб. п/о плен., 500 мг+600 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-oxyftauj8qh/toggleWishlist":{"skuId":"227814598","productId":1778176217,"offerId":"WC7z4dqMfVYMOpkmm2B3OA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQmsee48an3+8mEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI2aHzzwYQxtnQbBib1c8GIPfcwQc=","sign":"wNcZaXOX5i0JarJg4DoLjCMOHCnJnm7cbHrT2NlK5AI="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-oxyftauj8qh/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Цифран СТ таб. п/о плен., 500 мг+600 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 609 ₽
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  • Амоксициллин капс., 500 мг, 16 шт.
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    Амоксициллин капс., 500 мг, 16 шт.

    Рейтинг товара: 4.9 из 5
    на основе 64 оценки
    Цена 115 ₽
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  • Амоксиклав таб. п/о плен., 875 мг+125 мг, 14 шт.
    –19 %
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    Амоксиклав таб. п/о плен., 875 мг+125 мг, 14 шт.

    Рейтинг товара: 5 из 5
    на основе 43 оценки
    Цена 500 ₽ вместо 620
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  • Амоксициллин+Клавулановая кислота Экспресс таб. дисперг., 125 мг+31.25 мг, 14 шт.
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    Амоксициллин+Клавулановая кислота Экспресс таб. дисперг., 125 мг+31.25 мг, 14 шт.

    Рейтинг товара: 4.9 из 5
    на основе 20 оценок
    Цена 147 ₽
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  • Сумамед таб. п/о плен., 125 мг, 6 шт.
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    Сумамед таб. п/о плен., 125 мг, 6 шт.

    Рейтинг товара: 4.9 из 5
    на основе 33 оценки
    Цена 219 ₽
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  • Азитромицин капс., 500 мг, 3 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-lif2kdqg6ir/toggleWishlist":{"skuId":"186887755","productId":1434054437,"offerId":"XT06Hmnpb2B2OYpMK0MkhQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQmsee48an3+8mEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIpd7nqwUQy9yOWRjkpNUHIPfcwQc=","sign":"iM/qkI+7ysDQAiR9opQp4TAPMMbDcRf558YP/tuykSI="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-lif2kdqg6ir/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Азитромицин капс., 500 мг, 3 шт.

    Рейтинг товара: 4.7 из 5
    на основе 156 оценок
    Цена 96 ₽
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  • Цифран таб. п/о плен., 250 мг, 10 шт.
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    Цифран таб. п/о плен., 250 мг, 10 шт.

    Рейтинг товара: 4.7 из 5
    на основе 6 оценок
    Цена 48 ₽
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  • Флемоксин Солютаб таб. дисперг., 125 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-tnxkkcul6d/toggleWishlist":{"skuId":"101448168750","productId":1439627437,"offerId":"exzIVu6Dcf2tSraH5DZgxg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQmsee48an3+8mEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIrfG7rgUQruqg9vkCGNDf0Acg99zBBw==","sign":"sbx/pfzcQaS8PduObTS2LJusoWNrgeDiCfvuINUi4dg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-tnxkkcul6d/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Флемоксин Солютаб таб. дисперг., 125 мг, 20 шт.

    Рейтинг товара: 4.7 из 5
    на основе 30 оценок
    Цена 260 ₽
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  • Амоксициллин Экспресс таб. дисперг., 125 мг, 20 шт.
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    Амоксициллин Экспресс таб. дисперг., 125 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 241 ₽
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Инструкция

Показания к применению

Смешанные бактериальные инфекции, вызванные чувствительными грамположительными и грамотрицательными микроорганизмами, в ассоциации с анаэробными микроорганизмами и/или простейшими:
инфекции дыхательных путей (острый и хронический (в стадии обострения) бронхит, пневмония, бронхоэктатическая болезнь);
инфекции ЛОР-органов (средний отит, гайморит, фронтит, синусит, мастоидит, тонзиллит, фарингит);
инфекции ротовой полости (острый язвенный гингивит, периодонтит, периостит).
инфекции почек и мочевыводящих путей (цистит, пиелонефрит);
инфекции органов малого таза и половых органов (простатит, аднексит, сальпингит, оофорит, эндометрит, тубулярный абсцесс, пельвиоперитонит);
интраабдоминальные инфекции (инфекции желудочно-кишечного тракта, желчных путей, внутрибрюшинные абсцессы);
инфекции кожи и мягких тканей (инфицированные язвы, раны, ожоги, абсцессы, флегмона, язвенные поражения кожи при "синдроме диабетической стопы", пролежни);
инфекции костей и суставов (остеомиелит, септический артрит);
послеоперационные инфекции.

Противопоказания

Гиперчувствительность (в том числе, к производным фторхинолона или имидазола), заболевания крови (в анамнезе), угнетение костномозгового кроветворения, органические заболевания центральной нервной системы, беременность, период лактации, одновременный прием с тизанидином (риск выраженного снижения артериального давления, сонливости), острая порфирия, детский возраст до 18 лет.

Способ применения и дозы

Внутрь, за 1 час до еды или через 2 часа после еды, запивая достаточным количеством воды. Не следует разламывать, разжевывать или разрушать таблетку.
Рекомендуемая доза - 1 таблетка 2 раза в день в течение 5-10 дней.
Полная инструкция
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Ципролет А таб. п/о плен.
Ципролет А таб. п/о плен., 500 мг+600 мг, 10 шт.
5.0
(2)
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4 вопроса
Инструкция

371 ₽

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У продавца:2 оценки·0 отзывов
У всех продавцов:46 оценок·9 отзывов
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