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Описание

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Гепцифол таб., 400 мг, 20 шт.

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5.0
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Коротко о товаре

Артикул Маркета
512083838
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Повышенная утомляемость при установленных хронических заболеваниях печени."},{"name":"Противопоказания","value":"Генетические нарушения, влияющие на метиониновый цикл, и/или вызывающие гомоцистинурию и/или гипергомоцистеинемию (дефицит цистатионин бета-синтазы, нарушение метаболизма витамина В12 (цианокобаламина)).\u003Cbr\u003EГиперчувствительность к адеметионину и/или к любому из вспомогательных веществ в составе препарата.\u003Cbr\u003EВозраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности применения адеметионина в данной возрастной популяции).\u003Cbr\u003EБиполярные расстройства.\u003Cbr\u003EЕсли у Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска, перед применением препарата необходимо проконсультироваться с врачом."},{"name":"Состав","value":"Действующее вещество:\u003Cbr\u003EАдеметионина 1,4-бутандисульфонат - 760,00 мг.\u003Cbr\u003EВ пересчете на адеметионин - 400,00 мг.\u003Cbr\u003EВспомогательные вещества:\u003Cbr\u003EЯдро: кремния диоксид коллоидный - 6,00 мг; целлюлоза микрокристаллическая 200 - 100,00 мг; карбоксиметилкрахмал натрия (тип А) - 17,60 мг; магния стеарат - 4,40 мг.\u003Cbr\u003EОболочка кишечнорастворимая: гипромеллоза Е15 - 11,52 мг; метакриловой кислоты и этилакрилата сополимер 1:1 - 28,00 мг; макрогол 6000 - 10,28 мг; тальк - 21,376 мг; гидроксид натрия - 0,376 мг; полисорбат 80 - 0,448 мг."},{"name":"Действующее вещество","value":"Адеметионин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28710768"]}}},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EТаблетки следует принимать целиком, не разжевывая, желательно в первой половине дня между приемами пищи.\u003Cbr\u003EТаблетки препарата Гепцифолследует вынимать из блистера непосредственно перед приемом внутрь. В случае если таблетки имеют цвет, отличный от белого до почти белого цвета (вследствие негерметичности алюминиевой фольги), препарат Гепцифолприменять не рекомендуется.\u003Cbr\u003EРекомендуемая доза составляет 10-25 мг адеметионина на 1 кг массы тела в сутки.\u003Cbr\u003EОбычно суточная доза составляет 1-2 таблетки в сутки (от 400-800 мг адеметионина в сутки) и может быть увеличена до 4 таблеток в сутки (до 1600 мг адеметионина в сутки). Эффект обычно проявляется через 7-14 дней лечения и сохраняется при дальнейшем применении препарата.\u003Cbr\u003EПри отсутствии положительного эффекта от проводимой в течение 2 недель терапии препаратом или ухудшении состояния следует обратиться к врачу.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EКлинический опыт применения препарата Гепцифолне выявил каких-либо различий в его эффективности у пациентов пожилого возраста и пациентов более молодого возраста. Однако, учитывая высокую вероятность имеющихся нарушений функции печени, почек или сердца, другой сопутствующей патологии или одновременной терапии с другими лекарственными средствами, дозу препарата Гепцифолпожилым пациентам следует подбирать с осторожностью, начиная применение препарата с нижнего предела диапазона доз.\u003Cbr\u003EПочечная недостаточность\u003Cbr\u003EИмеются ограниченные клинические данные о применении препарата у пациентов с почечной недостаточностью, в связи с этим рекомендуется соблюдать осторожность при применении препарата Гепцифолу таких пациентов.\u003Cbr\u003EПеченочная недостаточность\u003Cbr\u003EПараметры фармакокинетики адеметионина сходны у здоровых добровольцев и у пациентов с хроническими заболеваниями печени.\u003Cbr\u003EДети и подростки до 18 лет\u003Cbr\u003EПрименение препарата Гепцифолу детей и подростков до 18 лет противопоказано (эффективность и безопасность не установлены)."},{"name":"Побочные действия","value":"Среди наиболее частых нежелательных реакций, выявленных в ходе клинических исследований с участием примерно 2000 пациентов, были: головная боль, тошнота и диарея.\u003Cbr\u003EНиже приведены данные о нежелательных реакциях, наблюдавшихся в ходе клинических исследований (n=1922) и в пострегистрационном периоде наблюдения («спонтанные» сообщения).\u003Cbr\u003EНежелательные реакции распределены по системно-органным классам и частоте их возникновения: очень часто (≥1/10); часто (≥1/100 и \u003C1/10); нечасто (≥1/1000 и \u003C1/100); редко (≥1/10000 и \u003C1/1000); очень редко (\u003C1/10000).\u003Cbr\u003EЕсли у Вас отмечаются нежелательные реакции, указанные в инструкции, или они усугубляются, или Вы заметили любые другие нежелательные реакции, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Адеметионин относится к группе гепатопротекторов. Оказывает желчегонное действие, обладает детоксикационными, регенерирующими, антиоксидантными, антифиброзирующими и нейропротективными свойствами.\u003Cbr\u003EАдеметионин (S-аденозил-L-метионин) - это аминокислота естественного происхождения, которая присутствует практически во всех тканях и биологических жидкостях в организме.\u003Cbr\u003EНаибольшая концентрация адеметионина отмечена в печени и мозге. Адеметионин является производным серосодержащей аминокислоты - метионина. Выполняет ключевую роль в метаболических процессах организма, принимает участие в важных биохимических реакциях. Участвует в синтезе фосфолипидов клеточных мембран, нейротрансмиттеров, нуклеиновых кислот, белков, гормонов и др. Адеметионин является предшественником цистеина, таурина, глутатиона (обеспечивая окислительно-восстановительный механизм клеточной детоксикации), коэнзима А (включается в биохимические реакции цикла трикарбоновых кислот и восполняет энергетический потенциал клетки). Повышает содержание глутамина в печени, цистеина и таурина в плазме; снижает содержание метионина в сыворотке, нормализуя метаболические реакции в печени. Опосредованно участвует в стимуляции регенерации и пролиферации клеток печени, что уменьшает риск фиброзирования. Адеметионин нормализует синтез эндогенного фосфатидилхолина в гепатоцитах, что повышает текучесть и поляризацию мембран. Это улучшает функцию ассоциированных с мембранами гепатоцитов транспортных систем желчных кислот и способствует пассажу желчных кислот в желчевыводящие пути. Эффективен при внутридольковом варианте холестаза (нарушение синтеза и тока желчи). Адеметионин снижает токсичность желчных кислот в клетках печени. У пациентов с диффузными заболеваниями печени (цирроз, гепатит) адеметионин снижает выраженность кожного зуда и способствует улучшению биохимических показателей крови, в т.ч. концентрации прямого билирубина, активности щелочной фосфатазы, аминотрансфераз и др. Желчегонный и гепатопротекторный эффект сохраняется до 3 месяцев после прекращения лечения. Показана эффективность при гепатопатиях, обусловленных различными гепатотоксичными препаратами. В ряде исследований была подтверждена эффективность адеметионина при лечении повышенной утомляемости у пациентов с хроническими заболеваниями печени."},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить в защищенном от света месте при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Передозировка препаратом Гепцифол® маловероятна. В случае передозировки препарата Гепцифол следует немедленно обратиться к врачу. Лечение: симптоматическое."},{"name":"Применение при беременности и кормлении грудью","value":"Перед применением препарата Гепцифол, если Вы беременны, или предполагаете, что Вы могли бы быть беременны, или планируете беременность, необходимо проконсультироваться с врачом. В период грудного вскармливания перед применением препарата Гепцифол® следует проконсультироваться с врачом. Применение препарата Гепцифол при беременности и в период грудного вскармливания не рекомендуется без наблюдения у врача."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При применении препарата Гепцифол возможны головокружение и снижение артериального давления. В случае появления данных нежелательных реакций следует воздержаться от управления транспортными средствами и механизмами до их исчезновения."},{"name":"Особые указания","value":"Одновременный прием с селективными ингибиторами обратного захвата серотонина (СИОЗС), трициклическими антидепрессантами (такими как кломипрамин), а также лекарственными средствами, содержащими триптофан, в том числе, растительного происхождения (см. раздел «Взаимодействие с другими лекарственными средствами»).\u003Cbr\u003EПожилой возраст.\u003Cbr\u003EПочечная недостаточность.\u003Cbr\u003EЕсли у Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска, перед применением препарата необходимо проконсультироваться с врачом."},{"name":"Взаимодействие","value":"Известных взаимодействий с другими лекарственными средствами не наблюдалось.\u003Cbr\u003EЕсли Вы применяете нижеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Гепцифолпроконсультируйтесь с врачом.\u003Cbr\u003EЕсть сообщение о синдроме избытка серотонина у пациента, принимавшего адеметионин и кломипрамин. Считается, что такое взаимодействие возможно, и следует с осторожностью применять адеметионин вместе с селективными ингибиторами обратного захвата серотонина, трициклическими антидепрессантами (такими как кломипрамин), а также лекарственными средствами, содержащими триптофан (в том числе, растительного происхождения)."},{"name":"Регистрационный номер","value":"ЛП-007441"},{"name":"Дата государственной регистрации","value":"09.03.2022"},{"name":"Владелец регистрационного удостоверения","value":"Фармасинтез","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:16003445"]}}},{"name":"Изготовитель","value":"Фармасинтез"},{"name":"Фасовщик","value":"Фармасинтез"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"1606297976818557573":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"печень"},{"name":"Назначение","value":"нарушение функции печени, поддержание работы печени"},{"name":"Показания к применению","value":"Вспомогательная терапия при установленных хронических заболеваниях печени, для улучшения и поддержания ее функций. Повышенная утомляемость при установленных хронических заболеваниях печени."},{"name":"Противопоказания","value":"Генетические нарушения, влияющие на метиониновый цикл, и/или вызывающие гомоцистинурию и/или гипергомоцистеинемию (дефицит цистатионин бета-синтазы, нарушение метаболизма витамина В12 (цианокобаламина)).\u003Cbr\u003EГиперчувствительность к адеметионину и/или к любому из вспомогательных веществ в составе препарата.\u003Cbr\u003EВозраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности применения адеметионина в данной возрастной популяции).\u003Cbr\u003EБиполярные расстройства.\u003Cbr\u003EЕсли у Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска, перед применением препарата необходимо проконсультироваться с врачом."},{"name":"Состав","value":"Действующее вещество:\u003Cbr\u003EАдеметионина 1,4-бутандисульфонат - 760,00 мг.\u003Cbr\u003EВ пересчете на адеметионин - 400,00 мг.\u003Cbr\u003EВспомогательные вещества:\u003Cbr\u003EЯдро: кремния диоксид коллоидный - 6,00 мг; целлюлоза микрокристаллическая 200 - 100,00 мг; карбоксиметилкрахмал натрия (тип А) - 17,60 мг; магния стеарат - 4,40 мг.\u003Cbr\u003EОболочка кишечнорастворимая: гипромеллоза Е15 - 11,52 мг; метакриловой кислоты и этилакрилата сополимер 1:1 - 28,00 мг; макрогол 6000 - 10,28 мг; тальк - 21,376 мг; гидроксид натрия - 0,376 мг; полисорбат 80 - 0,448 мг."},{"name":"Действующее вещество","value":"Адеметионин"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EТаблетки следует принимать целиком, не разжевывая, желательно в первой половине дня между приемами пищи.\u003Cbr\u003EТаблетки препарата Гепцифолследует вынимать из блистера непосредственно перед приемом внутрь. В случае если таблетки имеют цвет, отличный от белого до почти белого цвета (вследствие негерметичности алюминиевой фольги), препарат Гепцифолприменять не рекомендуется.\u003Cbr\u003EРекомендуемая доза составляет 10-25 мг адеметионина на 1 кг массы тела в сутки.\u003Cbr\u003EОбычно суточная доза составляет 1-2 таблетки в сутки (от 400-800 мг адеметионина в сутки) и может быть увеличена до 4 таблеток в сутки (до 1600 мг адеметионина в сутки). Эффект обычно проявляется через 7-14 дней лечения и сохраняется при дальнейшем применении препарата.\u003Cbr\u003EПри отсутствии положительного эффекта от проводимой в течение 2 недель терапии препаратом или ухудшении состояния следует обратиться к врачу.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EКлинический опыт применения препарата Гепцифолне выявил каких-либо различий в его эффективности у пациентов пожилого возраста и пациентов более молодого возраста. Однако, учитывая высокую вероятность имеющихся нарушений функции печени, почек или сердца, другой сопутствующей патологии или одновременной терапии с другими лекарственными средствами, дозу препарата Гепцифолпожилым пациентам следует подбирать с осторожностью, начиная применение препарата с нижнего предела диапазона доз.\u003Cbr\u003EПочечная недостаточность\u003Cbr\u003EИмеются ограниченные клинические данные о применении препарата у пациентов с почечной недостаточностью, в связи с этим рекомендуется соблюдать осторожность при применении препарата Гепцифолу таких пациентов.\u003Cbr\u003EПеченочная недостаточность\u003Cbr\u003EПараметры фармакокинетики адеметионина сходны у здоровых добровольцев и у пациентов с хроническими заболеваниями печени.\u003Cbr\u003EДети и подростки до 18 лет\u003Cbr\u003EПрименение препарата Гепцифолу детей и подростков до 18 лет противопоказано (эффективность и безопасность не установлены)."},{"name":"Побочные действия","value":"Среди наиболее частых нежелательных реакций, выявленных в ходе клинических исследований с участием примерно 2000 пациентов, были: головная боль, тошнота и диарея.\u003Cbr\u003EНиже приведены данные о нежелательных реакциях, наблюдавшихся в ходе клинических исследований (n=1922) и в пострегистрационном периоде наблюдения («спонтанные» сообщения).\u003Cbr\u003EНежелательные реакции распределены по системно-органным классам и частоте их возникновения: очень часто (≥1/10); часто (≥1/100 и \u003C1/10); нечасто (≥1/1000 и \u003C1/100); редко (≥1/10000 и \u003C1/1000); очень редко (\u003C1/10000).\u003Cbr\u003EЕсли у Вас отмечаются нежелательные реакции, указанные в инструкции, или они усугубляются, или Вы заметили любые другие нежелательные реакции, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Адеметионин относится к группе гепатопротекторов. Оказывает желчегонное действие, обладает детоксикационными, регенерирующими, антиоксидантными, антифиброзирующими и нейропротективными свойствами.\u003Cbr\u003EАдеметионин (S-аденозил-L-метионин) - это аминокислота естественного происхождения, которая присутствует практически во всех тканях и биологических жидкостях в организме.\u003Cbr\u003EНаибольшая концентрация адеметионина отмечена в печени и мозге. Адеметионин является производным серосодержащей аминокислоты - метионина. Выполняет ключевую роль в метаболических процессах организма, принимает участие в важных биохимических реакциях. Участвует в синтезе фосфолипидов клеточных мембран, нейротрансмиттеров, нуклеиновых кислот, белков, гормонов и др. Адеметионин является предшественником цистеина, таурина, глутатиона (обеспечивая окислительно-восстановительный механизм клеточной детоксикации), коэнзима А (включается в биохимические реакции цикла трикарбоновых кислот и восполняет энергетический потенциал клетки). Повышает содержание глутамина в печени, цистеина и таурина в плазме; снижает содержание метионина в сыворотке, нормализуя метаболические реакции в печени. Опосредованно участвует в стимуляции регенерации и пролиферации клеток печени, что уменьшает риск фиброзирования. Адеметионин нормализует синтез эндогенного фосфатидилхолина в гепатоцитах, что повышает текучесть и поляризацию мембран. Это улучшает функцию ассоциированных с мембранами гепатоцитов транспортных систем желчных кислот и способствует пассажу желчных кислот в желчевыводящие пути. Эффективен при внутридольковом варианте холестаза (нарушение синтеза и тока желчи). Адеметионин снижает токсичность желчных кислот в клетках печени. У пациентов с диффузными заболеваниями печени (цирроз, гепатит) адеметионин снижает выраженность кожного зуда и способствует улучшению биохимических показателей крови, в т.ч. концентрации прямого билирубина, активности щелочной фосфатазы, аминотрансфераз и др. Желчегонный и гепатопротекторный эффект сохраняется до 3 месяцев после прекращения лечения. Показана эффективность при гепатопатиях, обусловленных различными гепатотоксичными препаратами. В ряде исследований была подтверждена эффективность адеметионина при лечении повышенной утомляемости у пациентов с хроническими заболеваниями печени."},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить в защищенном от света месте при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Передозировка препаратом Гепцифол® маловероятна. В случае передозировки препарата Гепцифол следует немедленно обратиться к врачу. Лечение: симптоматическое."},{"name":"Применение при беременности и кормлении грудью","value":"Перед применением препарата Гепцифол, если Вы беременны, или предполагаете, что Вы могли бы быть беременны, или планируете беременность, необходимо проконсультироваться с врачом. В период грудного вскармливания перед применением препарата Гепцифол® следует проконсультироваться с врачом. Применение препарата Гепцифол при беременности и в период грудного вскармливания не рекомендуется без наблюдения у врача."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При применении препарата Гепцифол возможны головокружение и снижение артериального давления. В случае появления данных нежелательных реакций следует воздержаться от управления транспортными средствами и механизмами до их исчезновения."},{"name":"Особые указания","value":"Одновременный прием с селективными ингибиторами обратного захвата серотонина (СИОЗС), трициклическими антидепрессантами (такими как кломипрамин), а также лекарственными средствами, содержащими триптофан, в том числе, растительного происхождения (см. раздел «Взаимодействие с другими лекарственными средствами»).\u003Cbr\u003EПожилой возраст.\u003Cbr\u003EПочечная недостаточность.\u003Cbr\u003EЕсли у Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска, перед применением препарата необходимо проконсультироваться с врачом."},{"name":"Взаимодействие","value":"Известных взаимодействий с другими лекарственными средствами не наблюдалось.\u003Cbr\u003EЕсли Вы применяете нижеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Гепцифолпроконсультируйтесь с врачом.\u003Cbr\u003EЕсть сообщение о синдроме избытка серотонина у пациента, принимавшего адеметионин и кломипрамин. Считается, что такое взаимодействие возможно, и следует с осторожностью применять адеметионин вместе с селективными ингибиторами обратного захвата серотонина, трициклическими антидепрессантами (такими как кломипрамин), а также лекарственными средствами, содержащими триптофан (в том числе, растительного происхождения)."},{"name":"Регистрационный номер","value":"ЛП-007441"},{"name":"Дата государственной регистрации","value":"09.03.2022"},{"name":"Владелец регистрационного удостоверения","value":"Фармасинтез"},{"name":"Изготовитель","value":"Фармасинтез"},{"name":"Фасовщик","value":"Фармасинтез"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_4807033210504145740"}}}}
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  • Эссенциале форте Н капс., 300 мг, 30 шт.
    –1 %
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    Эссенциале форте Н капс., 300 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 247 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 751 ₽ вместо 759
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форте Н капс., 300 мг, 30 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  • Гептор таб. п/о кш/раств., 400 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2feg39raj0v/toggleWishlist":{"skuId":"228041336","productId":1400799573,"offerId":"XQkr_Bi3OPZ2uYQcrSXyLQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9/GFrYLt3r91EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI1YL6mwUQ+MTebBja1KEFINrZwQc=","sign":"xzLWxKtMhTeOrst7g/C7CPs2Rei/dRM+ilbECZR4cqk="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2feg39raj0v/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Гептор таб. п/о кш/раств., 400 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 45 оценок
    Цена 1 234 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2feg39raj0v/addToCartButton":{"offerId":"XQkr_Bi3OPZ2uYQcrSXyLQ","skuId":"228041336","pendingCartItem":{"productId":1400799573,"offerId":"XQkr_Bi3OPZ2uYQcrSXyLQ","showPlaceId":"OTNDnItfwRMjN9MRHuEMMo6KjgD-rVh3jGUbLPcI2m1eLH6ACGoLRyFGJAgVQ9GRgZJ2lQ6jAGqKVTAW4U-9nRAeyAdbW5TEcPHuuwT0za2zDmy9PwjM40U2hsAvxoAGx1ehQj1-RVQ0yX-7iS-8_g9JwR6yjERu_0k3_wgwe7bViMw0JiHb9lLiwro4sOkwChSh8Vx7vJa_MMv8VlEY3Q,,","feeShow":"OTNDnItfwRMjN9MRHuEMMo6KjgD-rVh3jGUbLPcI2m1eLH6ACGoLRyFGJAgVQ9GRgZJ2lQ6jAGqKVTAW4U-9nRAeyAdbW5TEcPHuuwT0za2zDmy9PwjM40U2hsAvxoAGx1ehQj1-RVQ0yX-7iS-8_g9JwR6yjERu_0k3_wgwe7bViMw0JiHb9lLiwro4sOkwChSh8Vx7vJa_MMv8VlEY3Q,,","skuId":"228041336","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"1234","currency":"RUR"},"hid":"15756506","name":"Гептор таб. п/о кш/раств., 400 мг, 20 шт.","label":"2www5ckzob2","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":1215212,"key":"img_id6304000360066024595.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96WFVmZtSFtMyb3yJJ0vvI_f_VoLwr8_fQDSzGtzWieo56ioTQqFxX88u5IMn4znkfHt0qp_lB0cPqXXL4acOAxAj3UuNsDK8fbB2hxqNX3u6gQQImiwNoCqXJtqgpDTxgD0mKokIVBVl9CAtJrXK7WmHd7ca3y__e2_RRyQ_eWu9szA5HWqh0tNvHLdQpbXXLfxr341FSiaQwnY0SAaRneWG3WCLgAcdVsw1U6zIBci7qxw3ODCw-darCe_MIPJ_JAGaOnK_6rJ_HcnYFCnBkHoykwwhJOg-Ykok3bV5dyVzfrkKLDzCoSo8cwhOFqHPPEg5qDv8KsMPJV7810CK5hjmJDBvV4fhaXnSG48AZZRzfFzw0rco3TyWm0UiMifJM_sOkJVl92OD_QmSA-rsBBBPZqs_G3Niao0hwoK5jWvS7__tX8EGfOBtDq8uF-3QcDn1s865j65nJIsmfEDb5aRRf3KOJ2E8OqSK_ULfbpeHxuwNd2QGuhVAgQ0Wj53e0d-0FHNoZ3o4Jd5DJuG_pdSQCsegoKi1Qcvr_PWeJ8EHW_yQ3s7BYI-EUnqoJPxkgsPSQnPiY73gRraiRaMng56rkLpujNk0KY-nBSpRfVOEhuVYfUYH3YWUSf0Z3bLI2xpT4yR8O1ea9h4j8OtSraojy10NknuL5g1U5d-RKx796N-B2JGQZuQz3ilW4fE_u5Db17p_XBxZD0lqCjcc9qZFHy5PR5MA0-NzwfzH6tXnWOR9RQoyHFayTEnOcTWKMF8T844DwmoCOy2BtBrUct6ApmrND3Oc3FQDGUJv-nOtz0UsNlsoiB6HtgU_AAntnjvAojXIpI1cgGM7RJlTnhPxdlbeotY9BoaRXOI_7561oLDIqLoKiqiRj8ckCtDqmWruwe_w7naRNRywM-_0jZWHnmTSVtrhDqEfhaC9Y-127hN0YY3VMVWrpQNgNKKs8A3mNsXY6tADk0Iau5AwHHT1yuAC8V8RsVrIlbpb8ivPyLeTg0N_S_SkixmMl8cR1wWtkCFEMYrDg1IUl7-p9Ph0p1aqZqTDn7sdzyV_nX1_RkBuj2WTTBKXKcdys4reeva0mui6KfwID4Qld1JHgCusEzhjJKsYuIKXAJ3quk4ucxEJ7Epha-cdUmEl2Gx4lm-KG-vz6AYt-LXAteViRyyp-ST_3tgXeQ_gFB8YYIKi9ur3ziVwGcELkA0skVKZUp6vx7Z1UjWe1AlUVA1r15U1EiLevKuZgQTcJ5fZWi2O8opXA36-5IG98-EWTO85iwyVtuO1rhimJ1JiO6Uey3CSBxPmA5dxHchTwB0aMuM3Ri7N9Nwpd50nNAJU6f-oy39Jwgo-tsgz-d4H8Qpybdj4s4uunN2Sc80xHIrAciJirP0lBCfwm8jODmSDu7zgGVTBn6_RZJ6DzKdSh_EulWQG2XK6c4SFKo67AYHqmfjf7CUY7dxF1wDOmwUcOlGZp26Nd_B6AhNAtVRT90rrZQQ34PCaaON8fIER6yP5TLnDYPILhwI5Bc2-T6s3h-W5YIW3y1WR_5sNKzxiYFhtcQpjzZ006qeaMQjdJNPt2ZV-rBChLoZviLTWmc-5i3Ypibov-V-kwBmJOI6NjZVF1nWCQrci4MdNKNwX5ddNVW3KLWjAm3-Rnzyk2VR5_xVSkl6ZSUQNWPHhIKlIlLx0wVf0wc9IaUcWIpVR1C5A8tf_4mcRnmAtKNbBAdDbMwUmVVF_-44MV6Ch3WgIyg83NPObdgbJWYjnPx6josQtxddj_zn_AGyVzuV_JmUA80crGuosY96JK8j_BPL1dZNWp7PaGfdtM3EvLQK01q1CYb5OGFNMxuSNXky7AivF5gNA3eoPmNSiqRQoMtFVD_DBPNLNFLkewQORqHrdhteGQSQhE2ALq-DEX1EffoDmXmHv0OJPE4yvnvb9S1gIf4PusFTvEXFlDjOuOXwtlSEfZ9B_nr6K2CGmVrOp4s3l3qL7RmNy5L8q8nlfURjhnbeNMRaQqFsctJg47w7uG78PZgvvqXftVEPifjKEMeWeu-LQuVL8LIz3oRLVq0LdBD7VK1x_PsVt9JyhTgi_pb7lpPjKAIBNbqYzHLWJYpI-UZc1WJzqfzqf93JK4TUexE81TYLGfQCgP50tEguCXLxkwOlNcWI52yKT4rpWUpBOtD3fYhjarY_0vaIxk6rHaPRSUbwbDLG7h07Gw2Yac8XMnVbXBKHSN2GD6J4iC9BmXWPasL2pW8uvezBLck0oNhTyDIasf3DkuGQTz75dYw-YMKPyCMaulh_cxISfBLBof3BwxAzSofftFukeFhIUmgjvNHTXcGpoN5EOdcWOtzsq012GPAAb332mPsnL079bQD586SVmqd01s4GX7zOqEnY3dYsxdE94I71WRwo64Ox7Rk_Onst9A8FqcnjHX1izXrO5PsPoHEEVKYm6LOwg_eQJpxJ2P-NHBMpDSHtlUgRd2yV0F2ZwQn9oEDEOVL79miX5ZOmODGSrANkobedd_Wbl6TQ3YLBsy_o3aJW95Q6-2NYpkUyG_yzD3qhKLHjzjwsnf62A0dGSWoU7wlqx__NaMbS9MdmOmr0kHGNl7SUxPy9p0YlyS67Hbba6clvYxhQbkc94tdSESrKPfGKX_f3Gk0_TyMdMtFoST2JBvCuxsA1cwope8K8p0o5Pq_5P9wiAq5i10idMmNgxVg7Vh5JGOke7IxAHwRYQUlQYb2t7nk9-2owiMbxymgQAF68EIBMwpp0BzzQngUQ66psi0XBjb4duhGJ3QeVG0P_dumxp2rTImpa2JFOARYPQgWX0EBiZZnjm6DJvlGjRhbFXtGvsgqCqGfVX7w9fLSvcxfyGqXp-H7GP_WmYK_8SnRJDdjln-aVayesPJ_q6Y6K4vqO6moEvwakvcWHKwJl4M9CY1v1ZwpQiIdgxs3LHNbGTANX0ryQO4yeHLURe1yhsecQzKdcPEg8y1BQEQ0GCS5YIYLAhuc-prB_Azoojfs8yKEYWf2Y-j6XLyZJhaNDFpaux36PgoaK4MVZ1QxXmW8itot3xtkiQZ-VJwMIbKB2LIwpNewQ0q6e7b7rL7odQH_Lp9pJ9hulizWeeI90HvzimvMdbLCyojkHuxQ2UXgJAuuRUuQnXmbqbGJMln49szyCkXzajtniLvADqrn-gkR7_tDTQUafQTdsBde-pWncIdyDYQG8cz8ciLErSUBuV1gJoa8M/b64e=1/sign=e7285130383eba21bf30e36498ad6b18/keyno=MARKET_1/*","showUid":"17179763797625688319706003","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9/GFrYLt3r91EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI1YL6mwUQ+MTebBja1KEFINrZwQc=","sign":"xzLWxKtMhTeOrst7g/C7CPs2Rei/dRM+ilbECZR4cqk="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9/GFrYLt3r91EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI1YL6mwUQ+MTebBja1KEFINrZwQc=","sign":"xzLWxKtMhTeOrst7g/C7CPs2Rei/dRM+ilbECZR4cqk="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2feg39raj0v/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Гептрал таб. п/о кш/раств., 400 мг, 20 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zaqvms2nnbp/toggleWishlist":{"skuId":"228043930","productId":1776700279,"offerId":"EILOhMlO6Qytc8MvZF6wGA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9/GFrYLt3r91EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI95aZzwYQmtnebBjQxN4HINrZwQc=","sign":"mGv40JoNMGnfhIHQXsgA1Ph4bPiuUcVqOv7gLnv6mXo="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zaqvms2nnbp/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Гептрал таб. п/о кш/раств., 400 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 250 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 844 ₽ вместо 1 863
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  • Адеметионин таб. кш/раств., 400 мг, 20 шт.
    –1 %
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    Адеметионин таб. кш/раств., 400 мг, 20 шт.

    Рейтинг товара: 4.4 из 5
    на основе 8 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 446 ₽ вместо 1 461
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  • Самеликс таб. п/о плен. кш/раств., 400 мг, 20 шт.
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    Самеликс таб. п/о плен. кш/раств., 400 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 1 320 ₽
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  • Гепцифол экспресс лиоф. д/приг. р-ра для в/в и в/м введ., 400 мг, 5 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-t6dikesvti/toggleWishlist":{"skuId":"101945274086","productId":1817177594,"offerId":"qCNmuxtF_mnB6NKdVguOVQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9/GFrYLt3r91EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI+tu/4gYQ5t2l4/sCGPXi0Acg2tnBBw==","sign":"sNKknc4xhIebcbyWqTBu0KXEMTrkVfNL0j3+XiSuV80="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-t6dikesvti/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Гепцифол экспресс лиоф. д/приг. р-ра для в/в и в/м введ., 400 мг, 5 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 1 411 ₽
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  • Гептразан таб. кш/раств., 400 мг, 20 шт.
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    Гептразан таб. кш/раств., 400 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 10 оценок
    Цена 1 058 ₽
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  • Фосфоглив капс., 50 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ed6ybaeq36i/toggleWishlist":{"skuId":"186847737","productId":1780856733,"offerId":"WTIVcWsu8ruwzOhVUI7CIw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9/GFrYLt3r91EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIne+W0QYQ+aOMWRiPvN4HINrZwQc=","sign":"34MajmHLDv5Ga6IqbygnxSpAcnGycas3LjimOFVfPJ4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ed6ybaeq36i/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Фосфоглив капс., 50 шт.

    Рейтинг товара: 4.8 из 5
    на основе 66 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 644 ₽ вместо 651
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  • Гептрал таб. п/о кш/раств., 500 мг, 20 шт.
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    Гептрал таб. п/о кш/раств., 500 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 8 оценок
    Цена 2 433 ₽
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  • Гептрал лиоф. для приг. р-ра для в/в и в/м введ. фл., 400 мг, 5 шт.
    –21 %
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    Гептрал лиоф. для приг. р-ра для в/в и в/м введ. фл., 400 мг, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 19 оценок
    Цена 1 932 ₽ вместо 2 445
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  • Гептрал лиоф. д/приг. р-ра для в/в и в/м введ. фл. р-ль амп., 400 мг, 5 шт.
    –12 %
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    Гептрал лиоф. д/приг. р-ра для в/в и в/м введ. фл. р-ль амп., 400 мг, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 52 оценки
    Цена 1 937 ₽ вместо 2 208
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Инструкция

Показания к применению

Вспомогательная терапия при установленных хронических заболеваниях печени, для улучшения и поддержания ее функций. Повышенная утомляемость при установленных хронических заболеваниях печени.

Противопоказания

Генетические нарушения, влияющие на метиониновый цикл, и/или вызывающие гомоцистинурию и/или гипергомоцистеинемию (дефицит цистатионин бета-синтазы, нарушение метаболизма витамина В12 (цианокобаламина)).
Гиперчувствительность к адеметионину и/или к любому из вспомогательных веществ в составе препарата.
Возраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности применения адеметионина в данной возрастной популяции).
Биполярные расстройства.
Если у Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска, перед применением препарата необходимо проконсультироваться с врачом.

Способ применения и дозы

Внутрь.
Таблетки следует принимать целиком, не разжевывая, желательно в первой половине дня между приемами пищи.
Таблетки препарата Гепцифолследует вынимать из блистера непосредственно перед приемом внутрь. В случае если таблетки имеют цвет, отличный от белого до почти белого цвета (вследствие негерметичности алюминиевой фольги), препарат Гепцифолприменять не рекомендуется.
Рекомендуемая доза составляет 10-25 мг адеметионина на 1 кг массы тела в сутки.
Обычно суточная доза составляет 1-2 таблетки в сутки (от 400-800 мг адеметионина в сутки) и может быть увеличена до 4 таблеток в сутки (до 1600 мг адеметионина в сутки). Эффект обычно проявляется через 7-14 дней лечения и сохраняется при дальнейшем применении препарата.
При отсутствии положительного эффекта от проводимой в течение 2 недель терапии препаратом или ухудшении состояния следует обратиться к врачу.
Пациенты пожилого возраста
Клинический опыт применения препарата Гепцифолне выявил каких-либо различий в его эффективности у пациентов пожилого возраста и пациентов более молодого возраста. Однако, учитывая высокую вероятность имеющихся нарушений функции печени, почек или сердца, другой сопутствующей патологии или одновременной терапии с другими лекарственными средствами, дозу препарата Гепцифолпожилым пациентам следует подбирать с осторожностью, начиная применение препарата с нижнего предела диапазона доз.
Почечная недостаточность
Имеются ограниченные клинические данные о применении препарата у пациентов с почечной недостаточностью, в связи с этим рекомендуется соблюдать осторожность при применении препарата Гепцифолу таких пациентов.
Печеночная недостаточность
Параметры фармакокинетики адеметионина сходны у здоровых добровольцев и у пациентов с хроническими заболеваниями печени.
Дети и подростки до 18 лет
Применение препарата Гепцифолу детей и подростков до 18 лет противопоказано (эффективность и безопасность не установлены).
Полная инструкция
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Гепцифол таб.
Гепцифол таб., 400 мг, 20 шт.
5.0
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