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Цитофлавин р-р для в/в введ. амп., 10 мл, 5 шт.

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5.0
(10)
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Количество штук в упаковке, шт.: 5

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Коротко о товаре

Артикул Маркета
3123944781
Тип препарата
Назначение
Действующее вещество
Форма выпуска
раствор для инъекций
Инструкция
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Не назначается пациентам (кроме периода новорождённости), находящимся в критическом состоянии, до стабилизации центральной гемодинамики и/или при снижении парциального давления кислорода в артериальной крови ниже 60 мм рт. ст.\u003Cbr\u003EС осторожностью\u003Cbr\u003EПри нефролитиазе, подагре, гиперурикемии. Если у Вас одно из перечисленных заболеваний, перед приёмом препарата ЦИТОФЛАВИН обязательно проконсультируйтесь с врачом. \u003Cbr\u003E"},{"name":"Состав","value":"Действующие вещества: янтарная кислота – 100 г, никотинамид – 10 г, инозин – 20 г, рибофлавин (рибофлавина фосфат\u003Cbr\u003Eнатрия) – 2 г; вспомогательные вещества: меглюмин (N-метилглюкамин) – 165 г, натрия гидроксид – 34 г, вода для инъекций – до 1,0 л.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Инозин+Никотинамид+Рибофлавин+Янтарная кислота","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:36089786"]}}},{"name":"Способ применения и дозы","value":"У взрослых\u003Cbr\u003EЦИТОФЛАВИН применяют только внутривенно капельно в разведении на 100–200 мл 5–10 % раствора декстрозы или 0,9 % раствора натрия хлорида.\u003Cbr\u003EСкорость введения 3–4 мл/мин.\u003Cbr\u003E1. При инфаркте мозга препарат вводят в максимально ранние сроки от начала развития заболевания в объёме 10 мл на введение с интервалом 8–12 часов в течение 10 дней. При тяжёлой форме течения заболевания разовую дозу увеличивают до 20 мл.\u003Cbr\u003E2. При последствиях цереброваскулярных болезней (инфаркта мозга, церебрального атеросклероза) препарат вводят в объёме 10 мл на введение один раз в сутки в течение 10 дней. \u003Cbr\u003E3. При токсической и гипоксической энцефалопатии препарат вводят в объёме 10 мл на введение два раза в сутки через 8–12 часов в течение 5 дней. При коматозном состоянии – в объёме 20 мл на введение в разведении на 200 мл раствора\u003Cbr\u003Eдекстрозы. При посленаркозном угнетении сознания – однократно в тех же дозах. В терапии гипоксической энцефалопатии при кардиохирургических операциях с использованием искусственного кровообращения вводят по 20 мл препарата\u003Cbr\u003Eв разведении на 200 мл 5 % раствора декстрозы за 3 дня до операции, в день операции, в течение 3 дней после операции.\u003Cbr\u003E4. Для профилактики когнитивных расстройств после обширных хирургических вмешательств у пациентов\u003Cbr\u003Eпожилого возраста препарат вводят в объёме 20 мл на введение в разведении на 200 мл 0,9 % раствора натрия\u003Cbr\u003Eхлорида. Курс лечения – 7 дней по схеме: первое введение – за сутки до операции; второе – интраоперационное введение\u003Cbr\u003Eпосле осуществления вводного наркоза (начало инфузии в течение 30 минут от начала операции), затем в течение__\u003Cbr\u003E5 дней после операции. В дальнейшем рекомендуется применение препарата «ЦИТОФЛАВИН таблетки, покрытые\u003Cbr\u003Eкишечнорастворимой оболочкой» по 2 таблетки 2 раза в сутки с интервалом между приёмами 8–10 часов в течение 25 дней.\u003Cbr\u003EУ детей (в том числе недоношенных) в периоде новорождённости с церебральной ишемией суточная доза препарата\u003Cbr\u003EЦИТОФЛАВИН составляет 2 мл/кг. Рассчитанную суточную дозу препарата вводят внутривенно капельно (медленно)\u003Cbr\u003Eпосле разведения в 5 % или 10 % растворе декстрозы (в соотношении не менее 1:5). Время первого введения – первые\u003Cbr\u003E12 часов после рождения; оптимальным временем для начала\u003Cbr\u003Eтерапии являются первые 2 часа жизни. Рекомендуется вводить приготовленный раствор с помощью инфузионного\u003Cbr\u003Eнасоса со скоростью от 1 до 4 мл/ч, обеспечивая равномерное поступление препарата в кровоток в течение суток, в зависимости от рассчитанного суточного объёма растворов для базисной терапии, состояния гемодинамики пациента и показателей кислотно-основного состояния. Курс лечения составляет в среднем 5 суток.\u003Cbr\u003E"},{"name":"Побочные действия","value":"По данным Всемирной организации здравоохранения, нежелательные реакции классифицированы в соответствии с частотой их развития следующим образом:\u003Cbr\u003E– очень частые (≥ 1/10);\u003Cbr\u003E– частые (≥ 1/100 – \u003C 1/10);\u003Cbr\u003E– нечастые (≥ 1/1000 – \u003C 1/100);\u003Cbr\u003E– редкие (≥ 1/10000 – \u003C 1/1000);\u003Cbr\u003E– очень редкие (\u003C 1/10000);\u003Cbr\u003E– частота неизвестна (не может быть определена на основе\u003Cbr\u003Eимеющихся данных).\u003Cbr\u003EНарушения со стороны иммунной системы: очень редко – реакции гиперчувствительности, анафилактический шок.\u003Cbr\u003EНарушения со стороны нервной системы: очень редко – головная боль, головокружение, парестезия, тремор, гипестезия.\u003Cbr\u003EНарушения психики: очень редко – психомоторное возбуждение (беспокойство, повышенная двигательная активность).\u003Cbr\u003EНарушения со стороны сердца: очень редко – тахикардия, кратковременные боли и дискомфорт в области грудной клетки, ощущение учащения или усиления сердечных сокращений.\u003Cbr\u003EНарушения со стороны сосудов: очень редко – повышение или понижение артериального давления, гиперемия или\u003Cbr\u003Eбледность кожных покровов разной степени выраженности.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов \u003Cbr\u003Eгрудной клетки и средостения: очень редко – затруднение дыхания (одышка), удушье, першение в горле, сухой кашель,\u003Cbr\u003Eосиплость голоса, парестезия в носу, дизосмия, бронхоспазм.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eочень редко – горечь, сухость, металлический привкус во рту, кратковременные боли и дискомфорт в эпигастральной\u003Cbr\u003Eобласти, тошнота, рвота, гипестезия полости рта, диспепсия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: очень редко – кожный зуд, сыпь, отёчность лица, крапивница,\u003Cbr\u003Eангионевротический отёк, потливость.\u003Cbr\u003EНарушения со стороны обмена веществ и питания: очень\u003Cbr\u003Eредко – транзиторная гипогликемия, гиперурикемия, обострение подагры. У детей (в том числе недоношенных) в периоде\u003Cbr\u003Eноворождённости возможно развитие алкалоза.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко – озноб, чувство жара, слабость, повышение температуры тела, боль и покраснение по ходу вены.\u003Cbr\u003EЛабораторные и инструментальные данные: очень редко – учащённое дыхание.\u003Cbr\u003EВо избежание возникновения нежелательных реакций рекомендуется соблюдать режим дозирования и скорость введения\u003Cbr\u003Eпрепарата.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются или Вы заметили любые другие нежелательные реакции, не указанные в инструкции,\u003Cbr\u003Eсообщите об этом врачу.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Фармакологические эффекты обусловлены комплексным воздействием входящих в состав препарата ЦИТОФЛАВИН\u003Cbr\u003Eвеществ. ЦИТОФЛАВИН усиливает интенсивность аэробного гликолиза, что приводит к активации утилизации глюкозы\u003Cbr\u003Eи β-окисления жирных кислот, а также стимулирует синтез γ-аминомасляной кислоты в нейронах. ЦИТОФЛАВИН увеличивает устойчивость мембран нервных и глиальных клеток к ишемии, что выражается в снижении концентрации нейроспецифических белков, характеризующих уровень деструкции основных структурных компонентов нервной ткани.\u003Cbr\u003EЦИТОФЛАВИН улучшает коронарный и мозговой кровотоки, активирует метаболические процессы в центральной нерв-\u003Cbr\u003Eной системе, восстанавливает нарушенное сознание, способствует регрессу неврологической симптоматики и улучшению когнитивных функций мозга. Обладает быстрым пробуждающим действием при посленаркозном угнетении сознания.\u003Cbr\u003EПри применении препарата ЦИТОФЛАВИН в первые 12 часов от начала развития инсульта наблюдаются благоприятное течение ишемических и некротических процессов в зоне поражения (уменьшение очага), восстановление неврологического статуса и снижение уровня инвалидизации\u003Cbr\u003Eв отдалённом периоде.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"препараты для лечения заболеваний нервной системы прочие"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763748"]}}},{"name":"Условия хранения","value":"В защищённом от света месте при температуре не выше 25 ºС.\u003Cbr\u003EХранить в недоступном для детей месте.\u003Cbr\u003E"},{"name":"Передозировка","value":"Случаев передозировки не наблюдалось. При передозировке проводить симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"ЦИТОФЛАВИН противопоказан при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Необходимо соблюдать осторожность при управлении транспортными средствами и работе с точными механизмами из-за\u003Cbr\u003Eвозможного развития побочного действия (головокружение, психомоторное возбуждение). При развитии указанных\u003Cbr\u003Eпобочных эффектов необходимо отказаться от управления транспортными средствами и работе с точными механизмами.\u003Cbr\u003E"},{"name":"Особые указания","value":"Введение препарата новорождённым (недоношенным) детям осуществлять под контролем показателей кислотно-основного\u003Cbr\u003Eсостояния капиллярной крови не реже 2 раз в сутки (как перед началом, так и в процессе терапии). По возможности следует\u003Cbr\u003Eконтролировать показатели сывороточного лактата и глюкозы. Скорость введения раствора, содержащего ЦИТОФЛАВИН,\u003Cbr\u003Eследует уменьшить или временно прекратить инфузию новорождённым (недоношенным) детям:\u003Cbr\u003E– находящимся на искусственной вентиляции лёгких – при появлении признаков смешанного (респираторно-метаболического) алкалоза, угрожающего развитием нарушений мозгового кровообращения;\u003Cbr\u003E– при сохранённом спонтанном дыхании и респираторной поддержке методом постоянного положительного давления\u003Cbr\u003Eв дыхательных путях (СИПАП) или получающим воздушно- кислородную смесь через маску – при появлении лабораторных признаков метаболического алкалоза, угрожающего появлением или учащением приступов апноэ. У больных сахарным диабетом лечение проводить под\u003Cbr\u003Eконтролем показателя глюкозы крови. Возможно интенсивное окрашивание мочи в жёлтый цвет.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Янтарная кислота, инозин, никотинамид совместимы с другими лекарственными средствами.\u003Cbr\u003EРибофлавин уменьшает активность доксициклина, тетрациклина, окситетрациклина, эритромицина и линкомицина.\u003Cbr\u003EНесовместим со стрептомицином.\u003Cbr\u003EХлорпромазин, имипрамин, амитриптилин за счёт блокады флавинокиназы нарушают включение рибофлавина во\u003Cbr\u003Eфлавинаденинмононуклеотид и флавинадениндинуклеотид и увеличивают его выведение с мочой. Тиреоидные гормоны ускоряют метаболизм рибофлавина. Уменьшает и предупреждает побочные эффекты хлорамфеникола (нарушение гемопоэза, неврит зрительного нерва). Совместим с препаратами, стимулирующими гемопоэз, антигипоксантами, анаболическими стероидами.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"P N003135/01"},{"name":"Дата государственной регистрации","value":"22.03.2019"},{"name":"Владелец регистрационного удостоверения","value":"Полисан","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:16001556"]}}},{"name":"Изготовитель","value":"Полисан"},{"name":"Фасовщик","value":"Полисан"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Цитофлавин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18035719"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"5956337592106283257":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"головной мозг, кровеносные сосуды, нервная система"},{"name":"Назначение","value":"атеросклероз сосудов головного мозга, ишемический инсульт, острые отравления, профилактика и лечение ишемических неврологических расстройств, состояния после хирургических вмешательств, улучшение кровоснабжения головного мозга, цереброваскулярная недостаточность, энцефалопатия"},{"name":"Показания к применению","value":"У взрослых в комплексной терапии:\u003Cbr\u003E– инфаркта мозга;\u003Cbr\u003E– последствий цереброваскулярных болезней (инфаркта мозга, церебрального атеросклероза);\u003Cbr\u003E– токсической и гипоксической энцефалопатии при острых и хронических отравлениях, эндотоксикозах, посленаркозном угнетении сознания, а также для профилактики и лечения гипоксической энцефалопатии при кардиохирургических операциях с использованием искусственного кровообращения, для профилактики когнитивных расстройств после обширных хирургических вмешательств у пациентов пожилого возраста.\u003Cbr\u003EУ детей (в том числе недоношенных со сроком гестации 28–36 недель) в комплексной терапии в периоде новорождённости:\u003Cbr\u003E– при церебральной ишемии.\u003Cbr\u003E"},{"name":"Противопоказания","value":"Индивидуальная непереносимость компонентов препарата, беременность, период грудного вскармливания. Не назначается пациентам (кроме периода новорождённости), находящимся в критическом состоянии, до стабилизации центральной гемодинамики и/или при снижении парциального давления кислорода в артериальной крови ниже 60 мм рт. ст.\u003Cbr\u003EС осторожностью\u003Cbr\u003EПри нефролитиазе, подагре, гиперурикемии. Если у Вас одно из перечисленных заболеваний, перед приёмом препарата ЦИТОФЛАВИН обязательно проконсультируйтесь с врачом. \u003Cbr\u003E"},{"name":"Состав","value":"Действующие вещества: янтарная кислота – 100 г, никотинамид – 10 г, инозин – 20 г, рибофлавин (рибофлавина фосфат\u003Cbr\u003Eнатрия) – 2 г; вспомогательные вещества: меглюмин (N-метилглюкамин) – 165 г, натрия гидроксид – 34 г, вода для инъекций – до 1,0 л.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Инозин+Никотинамид+Рибофлавин+Янтарная кислота"},{"name":"Способ применения и дозы","value":"У взрослых\u003Cbr\u003EЦИТОФЛАВИН применяют только внутривенно капельно в разведении на 100–200 мл 5–10 % раствора декстрозы или 0,9 % раствора натрия хлорида.\u003Cbr\u003EСкорость введения 3–4 мл/мин.\u003Cbr\u003E1. При инфаркте мозга препарат вводят в максимально ранние сроки от начала развития заболевания в объёме 10 мл на введение с интервалом 8–12 часов в течение 10 дней. При тяжёлой форме течения заболевания разовую дозу увеличивают до 20 мл.\u003Cbr\u003E2. При последствиях цереброваскулярных болезней (инфаркта мозга, церебрального атеросклероза) препарат вводят в объёме 10 мл на введение один раз в сутки в течение 10 дней. \u003Cbr\u003E3. При токсической и гипоксической энцефалопатии препарат вводят в объёме 10 мл на введение два раза в сутки через 8–12 часов в течение 5 дней. При коматозном состоянии – в объёме 20 мл на введение в разведении на 200 мл раствора\u003Cbr\u003Eдекстрозы. При посленаркозном угнетении сознания – однократно в тех же дозах. В терапии гипоксической энцефалопатии при кардиохирургических операциях с использованием искусственного кровообращения вводят по 20 мл препарата\u003Cbr\u003Eв разведении на 200 мл 5 % раствора декстрозы за 3 дня до операции, в день операции, в течение 3 дней после операции.\u003Cbr\u003E4. Для профилактики когнитивных расстройств после обширных хирургических вмешательств у пациентов\u003Cbr\u003Eпожилого возраста препарат вводят в объёме 20 мл на введение в разведении на 200 мл 0,9 % раствора натрия\u003Cbr\u003Eхлорида. Курс лечения – 7 дней по схеме: первое введение – за сутки до операции; второе – интраоперационное введение\u003Cbr\u003Eпосле осуществления вводного наркоза (начало инфузии в течение 30 минут от начала операции), затем в течение__\u003Cbr\u003E5 дней после операции. В дальнейшем рекомендуется применение препарата «ЦИТОФЛАВИН таблетки, покрытые\u003Cbr\u003Eкишечнорастворимой оболочкой» по 2 таблетки 2 раза в сутки с интервалом между приёмами 8–10 часов в течение 25 дней.\u003Cbr\u003EУ детей (в том числе недоношенных) в периоде новорождённости с церебральной ишемией суточная доза препарата\u003Cbr\u003EЦИТОФЛАВИН составляет 2 мл/кг. Рассчитанную суточную дозу препарата вводят внутривенно капельно (медленно)\u003Cbr\u003Eпосле разведения в 5 % или 10 % растворе декстрозы (в соотношении не менее 1:5). Время первого введения – первые\u003Cbr\u003E12 часов после рождения; оптимальным временем для начала\u003Cbr\u003Eтерапии являются первые 2 часа жизни. Рекомендуется вводить приготовленный раствор с помощью инфузионного\u003Cbr\u003Eнасоса со скоростью от 1 до 4 мл/ч, обеспечивая равномерное поступление препарата в кровоток в течение суток, в зависимости от рассчитанного суточного объёма растворов для базисной терапии, состояния гемодинамики пациента и показателей кислотно-основного состояния. Курс лечения составляет в среднем 5 суток.\u003Cbr\u003E"},{"name":"Побочные действия","value":"По данным Всемирной организации здравоохранения, нежелательные реакции классифицированы в соответствии с частотой их развития следующим образом:\u003Cbr\u003E– очень частые (≥ 1/10);\u003Cbr\u003E– частые (≥ 1/100 – \u003C 1/10);\u003Cbr\u003E– нечастые (≥ 1/1000 – \u003C 1/100);\u003Cbr\u003E– редкие (≥ 1/10000 – \u003C 1/1000);\u003Cbr\u003E– очень редкие (\u003C 1/10000);\u003Cbr\u003E– частота неизвестна (не может быть определена на основе\u003Cbr\u003Eимеющихся данных).\u003Cbr\u003EНарушения со стороны иммунной системы: очень редко – реакции гиперчувствительности, анафилактический шок.\u003Cbr\u003EНарушения со стороны нервной системы: очень редко – головная боль, головокружение, парестезия, тремор, гипестезия.\u003Cbr\u003EНарушения психики: очень редко – психомоторное возбуждение (беспокойство, повышенная двигательная активность).\u003Cbr\u003EНарушения со стороны сердца: очень редко – тахикардия, кратковременные боли и дискомфорт в области грудной клетки, ощущение учащения или усиления сердечных сокращений.\u003Cbr\u003EНарушения со стороны сосудов: очень редко – повышение или понижение артериального давления, гиперемия или\u003Cbr\u003Eбледность кожных покровов разной степени выраженности.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов \u003Cbr\u003Eгрудной клетки и средостения: очень редко – затруднение дыхания (одышка), удушье, першение в горле, сухой кашель,\u003Cbr\u003Eосиплость голоса, парестезия в носу, дизосмия, бронхоспазм.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eочень редко – горечь, сухость, металлический привкус во рту, кратковременные боли и дискомфорт в эпигастральной\u003Cbr\u003Eобласти, тошнота, рвота, гипестезия полости рта, диспепсия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: очень редко – кожный зуд, сыпь, отёчность лица, крапивница,\u003Cbr\u003Eангионевротический отёк, потливость.\u003Cbr\u003EНарушения со стороны обмена веществ и питания: очень\u003Cbr\u003Eредко – транзиторная гипогликемия, гиперурикемия, обострение подагры. У детей (в том числе недоношенных) в периоде\u003Cbr\u003Eноворождённости возможно развитие алкалоза.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко – озноб, чувство жара, слабость, повышение температуры тела, боль и покраснение по ходу вены.\u003Cbr\u003EЛабораторные и инструментальные данные: очень редко – учащённое дыхание.\u003Cbr\u003EВо избежание возникновения нежелательных реакций рекомендуется соблюдать режим дозирования и скорость введения\u003Cbr\u003Eпрепарата.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются или Вы заметили любые другие нежелательные реакции, не указанные в инструкции,\u003Cbr\u003Eсообщите об этом врачу.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Фармакологические эффекты обусловлены комплексным воздействием входящих в состав препарата ЦИТОФЛАВИН\u003Cbr\u003Eвеществ. ЦИТОФЛАВИН усиливает интенсивность аэробного гликолиза, что приводит к активации утилизации глюкозы\u003Cbr\u003Eи β-окисления жирных кислот, а также стимулирует синтез γ-аминомасляной кислоты в нейронах. ЦИТОФЛАВИН увеличивает устойчивость мембран нервных и глиальных клеток к ишемии, что выражается в снижении концентрации нейроспецифических белков, характеризующих уровень деструкции основных структурных компонентов нервной ткани.\u003Cbr\u003EЦИТОФЛАВИН улучшает коронарный и мозговой кровотоки, активирует метаболические процессы в центральной нерв-\u003Cbr\u003Eной системе, восстанавливает нарушенное сознание, способствует регрессу неврологической симптоматики и улучшению когнитивных функций мозга. Обладает быстрым пробуждающим действием при посленаркозном угнетении сознания.\u003Cbr\u003EПри применении препарата ЦИТОФЛАВИН в первые 12 часов от начала развития инсульта наблюдаются благоприятное течение ишемических и некротических процессов в зоне поражения (уменьшение очага), восстановление неврологического статуса и снижение уровня инвалидизации\u003Cbr\u003Eв отдалённом периоде.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"препараты для лечения заболеваний нервной системы прочие"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищённом от света месте при температуре не выше 25 ºС.\u003Cbr\u003EХранить в недоступном для детей месте.\u003Cbr\u003E"},{"name":"Передозировка","value":"Случаев передозировки не наблюдалось. При передозировке проводить симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"ЦИТОФЛАВИН противопоказан при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Необходимо соблюдать осторожность при управлении транспортными средствами и работе с точными механизмами из-за\u003Cbr\u003Eвозможного развития побочного действия (головокружение, психомоторное возбуждение). При развитии указанных\u003Cbr\u003Eпобочных эффектов необходимо отказаться от управления транспортными средствами и работе с точными механизмами.\u003Cbr\u003E"},{"name":"Особые указания","value":"Введение препарата новорождённым (недоношенным) детям осуществлять под контролем показателей кислотно-основного\u003Cbr\u003Eсостояния капиллярной крови не реже 2 раз в сутки (как перед началом, так и в процессе терапии). По возможности следует\u003Cbr\u003Eконтролировать показатели сывороточного лактата и глюкозы. Скорость введения раствора, содержащего ЦИТОФЛАВИН,\u003Cbr\u003Eследует уменьшить или временно прекратить инфузию новорождённым (недоношенным) детям:\u003Cbr\u003E– находящимся на искусственной вентиляции лёгких – при появлении признаков смешанного (респираторно-метаболического) алкалоза, угрожающего развитием нарушений мозгового кровообращения;\u003Cbr\u003E– при сохранённом спонтанном дыхании и респираторной поддержке методом постоянного положительного давления\u003Cbr\u003Eв дыхательных путях (СИПАП) или получающим воздушно- кислородную смесь через маску – при появлении лабораторных признаков метаболического алкалоза, угрожающего появлением или учащением приступов апноэ. У больных сахарным диабетом лечение проводить под\u003Cbr\u003Eконтролем показателя глюкозы крови. Возможно интенсивное окрашивание мочи в жёлтый цвет.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Янтарная кислота, инозин, никотинамид совместимы с другими лекарственными средствами.\u003Cbr\u003EРибофлавин уменьшает активность доксициклина, тетрациклина, окситетрациклина, эритромицина и линкомицина.\u003Cbr\u003EНесовместим со стрептомицином.\u003Cbr\u003EХлорпромазин, имипрамин, амитриптилин за счёт блокады флавинокиназы нарушают включение рибофлавина во\u003Cbr\u003Eфлавинаденинмононуклеотид и флавинадениндинуклеотид и увеличивают его выведение с мочой. Тиреоидные гормоны ускоряют метаболизм рибофлавина. Уменьшает и предупреждает побочные эффекты хлорамфеникола (нарушение гемопоэза, неврит зрительного нерва). Совместим с препаратами, стимулирующими гемопоэз, антигипоксантами, анаболическими стероидами.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"P N003135/01"},{"name":"Дата государственной регистрации","value":"22.03.2019"},{"name":"Владелец регистрационного удостоверения","value":"Полисан"},{"name":"Изготовитель","value":"Полисан"},{"name":"Фасовщик","value":"Полисан"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Цитофлавин"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_9970049681175558557"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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765 ₽

  • Сегодня, самовывоз • 0 ₽
ЕАПТЕКА
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  • Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-iv06xmiehxn/toggleWishlist":{"skuId":"663185003","productId":1404748600,"offerId":"gE2pEneF5kJJmQH5baoh8w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQycGftI+v1q5/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIuIbrnQUQ68ydvAIYre38BSDt2cEH","sign":"K7AXDB0IaKfwREnnTdNbAWPJrQM1bZ4XBo0Sb9R5I88="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-iv06xmiehxn/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 11 оценок
    Цена 1 013 ₽
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  • Атаракс таб. п/о плен., 25 мг, 25 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-1nsc374y83p/toggleWishlist":{"skuId":"228073941","productId":1404748557,"offerId":"dICEtFdqQ71DwTS0QM9M_A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQycGftI+v1q5/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIjYbrnQUQ1cPgbBig2q4IIO3ZwQc=","sign":"IW2zVkwj+i42D18d43IDPWnwujRMNhbHaNYavdRYGDo="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-1nsc374y83p/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Атаракс таб. п/о плен., 25 мг, 25 шт.

    Рейтинг товара: 4.6 из 5
    на основе 154 оценки
    Цена 122 ₽
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  • Церебролизин р-р д/ин. амп., 5 мл, 5 шт.
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    Церебролизин р-р д/ин. амп., 5 мл, 5 шт.

    Рейтинг товара: 4.9 из 5
    на основе 18 оценок
    Цена 1 049 ₽
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  • Кортексин лиоф. д/приг. р-ра для в/м введ. фл., 10 мг, 0.22 г, 10 шт.
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    Кортексин лиоф. д/приг. р-ра для в/м введ. фл., 10 мг, 0.22 г, 10 шт.

    Рейтинг товара: 4.8 из 5
    на основе 51 оценка
    Цена 1 707 ₽
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  • Эврин р-р для в/в и в/м введ. амп., 50 мг/мл, 5 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2gqa456rjao/toggleWishlist":{"skuId":"862563253","productId":1404748772,"offerId":"3gHxcDk75DtMFy94-qytbw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQycGftI+v1q5/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI5IfrnQUQtdemmwMYh97QByDt2cEH","sign":"uRjWf7sWGJAx1RB872UClRFJ6LET53+KMPAEy4Vi7P0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2gqa456rjao/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эврин р-р для в/в и в/м введ. амп., 50 мг/мл, 5 мл, 5 шт.

    Рейтинг товара: 3 из 5
    на основе 4 оценки
    Цена 401 ₽
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  • Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 5 мл, 5 шт.
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    Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 5 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 531 ₽
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  • Мексидол таб. п/о плен., 125 мг, 30 шт.
    –17 %
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    Мексидол таб. п/о плен., 125 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 62 оценки
    Цена 293 ₽ вместо 355
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  • Цитореан таб. п/о плен., 125 мг, 60 шт.
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    Цитореан таб. п/о плен., 125 мг, 60 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 339 ₽
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  • Цераксон р-р д/вн. приема, 100 мг/мл, 10 мл, 10 шт.
    –17 %
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    Цераксон р-р д/вн. приема, 100 мг/мл, 10 мл, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 25 оценок
    Цена 2 618 ₽ вместо 3 142
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  • Фенибут таб., 250 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-maccqghe82o/toggleWishlist":{"skuId":"862513045","productId":1404748601,"offerId":"hlvpHnxI-qsMFeB05zZrKQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQycGftI+v1q5/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIuYbrnQUQlc+jmwMYs+DQByDt2cEH","sign":"blISU4APggRPTiXY26ZXPboupSXH/8XGDRFhN2E335E="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-maccqghe82o/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Фенибут таб., 250 мг, 10 шт.

    Рейтинг товара: 4.8 из 5
    на основе 324 оценки
    Цена 92 ₽
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  • Ренобрейн СМ лиоф. д/приг. р-ра для в/м введ. фл., 10 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-3ayaotc76ab/toggleWishlist":{"skuId":"101842711765","productId":1775334801,"offerId":"h658O4_gGI82rqJ3jGkdlw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQycGftI+v1q5/EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIkevFzgYQ1emxsvsCGN7j0Acg7dnBBw==","sign":"akrY0sitjp2fX4JasQgcBSTMb6RLHOnuZab8BC6ieIY="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-3ayaotc76ab/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ренобрейн СМ лиоф. д/приг. р-ра для в/м введ. фл., 10 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 1 437 ₽
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Инструкция

Показания к применению

У взрослых в комплексной терапии:
– инфаркта мозга;
– последствий цереброваскулярных болезней (инфаркта мозга, церебрального атеросклероза);
– токсической и гипоксической энцефалопатии при острых и хронических отравлениях, эндотоксикозах, посленаркозном угнетении сознания, а также для профилактики и лечения гипоксической энцефалопатии при кардиохирургических операциях с использованием искусственного кровообращения, для профилактики когнитивных расстройств после обширных хирургических вмешательств у пациентов пожилого возраста.
У детей (в том числе недоношенных со сроком гестации 28–36 недель) в комплексной терапии в периоде новорождённости:
– при церебральной ишемии.

Противопоказания

Индивидуальная непереносимость компонентов препарата, беременность, период грудного вскармливания. Не назначается пациентам (кроме периода новорождённости), находящимся в критическом состоянии, до стабилизации центральной гемодинамики и/или при снижении парциального давления кислорода в артериальной крови ниже 60 мм рт. ст.
С осторожностью
При нефролитиазе, подагре, гиперурикемии. Если у Вас одно из перечисленных заболеваний, перед приёмом препарата ЦИТОФЛАВИН обязательно проконсультируйтесь с врачом.

Способ применения и дозы

У взрослых
ЦИТОФЛАВИН применяют только внутривенно капельно в разведении на 100–200 мл 5–10 % раствора декстрозы или 0,9 % раствора натрия хлорида.
Скорость введения 3–4 мл/мин.
1. При инфаркте мозга препарат вводят в максимально ранние сроки от начала развития заболевания в объёме 10 мл на введение с интервалом 8–12 часов в течение 10 дней. При тяжёлой форме течения заболевания разовую дозу увеличивают до 20 мл.
2. При последствиях цереброваскулярных болезней (инфаркта мозга, церебрального атеросклероза) препарат вводят в объёме 10 мл на введение один раз в сутки в течение 10 дней.
3. При токсической и гипоксической энцефалопатии препарат вводят в объёме 10 мл на введение два раза в сутки через 8–12 часов в течение 5 дней. При коматозном состоянии – в объёме 20 мл на введение в разведении на 200 мл раствора
декстрозы. При посленаркозном угнетении сознания – однократно в тех же дозах. В терапии гипоксической энцефалопатии при кардиохирургических операциях с использованием искусственного кровообращения вводят по 20 мл препарата
в разведении на 200 мл 5 % раствора декстрозы за 3 дня до операции, в день операции, в течение 3 дней после операции.
4. Для профилактики когнитивных расстройств после обширных хирургических вмешательств у пациентов
пожилого возраста препарат вводят в объёме 20 мл на введение в разведении на 200 мл 0,9 % раствора натрия
хлорида. Курс лечения – 7 дней по схеме: первое введение – за сутки до операции; второе – интраоперационное введение
после осуществления вводного наркоза (начало инфузии в течение 30 минут от начала операции), затем в течение__
5 дней после операции. В дальнейшем рекомендуется применение препарата «ЦИТОФЛАВИН таблетки, покрытые
кишечнорастворимой оболочкой» по 2 таблетки 2 раза в сутки с интервалом между приёмами 8–10 часов в течение 25 дней.
У детей (в том числе недоношенных) в периоде новорождённости с церебральной ишемией суточная доза препарата
ЦИТОФЛАВИН составляет 2 мл/кг. Рассчитанную суточную дозу препарата вводят внутривенно капельно (медленно)
после разведения в 5 % или 10 % растворе декстрозы (в соотношении не менее 1:5). Время первого введения – первые
12 часов после рождения; оптимальным временем для начала
терапии являются первые 2 часа жизни. Рекомендуется вводить приготовленный раствор с помощью инфузионного
насоса со скоростью от 1 до 4 мл/ч, обеспечивая равномерное поступление препарата в кровоток в течение суток, в зависимости от рассчитанного суточного объёма растворов для базисной терапии, состояния гемодинамики пациента и показателей кислотно-основного состояния. Курс лечения составляет в среднем 5 суток.
Полная инструкция
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Цитофлавин р-р для в/в введ. амп.
Цитофлавин р-р для в/в введ. амп., 10 мл, 5 шт.
5.0
(10)
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3 вопроса
Инструкция

765 ₽

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5.0
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У продавца:10 оценок·1 отзыв
У всех продавцов:66 оценок·19 отзывов
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user avatar
7 месяцев назад • Имя скрыто • Куплен на Маркете
Достоинства: Отличный препарат, назначает терапевт
Недостатки: Недостатки не выявлены
Посмотреть все отзывы на Маркете
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