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Описание

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Бретарис Дженуэйр пор. д/инг. дозир., 322 мкг/доза, 60 шт.

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3.7
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Коротко о товаре

Артикул Маркета
4392522319
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"15661926898143353328":{"specItems":[{"name":"Артикул Маркета","value":"4392522319","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"хроническая обструктивная болезнь легких","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["36476390:36619005"]}}},{"name":"действующее вещество","value":"Аклидиния бромид","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["27144131:28710456"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"порошок для ингаляций"},{"name":"страна-производитель","value":"Испания"}]}},"compactSpecs":{"15661926898143353328":{"specItems":[{"name":"Артикул Маркета","value":"4392522319","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Назначение","value":"Хроническая обструктивная болезнь легких","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["36476390:36619005"]}}},{"name":"Действующее вещество","value":"Аклидиния бромид","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["27144131:28710456"]}}},{"name":"Возраст","value":"От 18 лет"}]}},"fullSpecs":{"15661926898143353328":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"дыхательная система"},{"name":"Назначение","value":"хроническая обструктивная болезнь легких","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["36476390:36619005"]}}},{"name":"Показания к применению","value":"Препарат Бретарис Дженуэйр предназначен для поддерживающей бронходилатирующей терапии с целью облегчения симптомов хронической обструктивной болезни легких (ХОБЛ) у взрослых."},{"name":"Противопоказания","value":"- Повышенная чувствительность к аклидиния бромиду, атропину и его производным (ипратропий, окситропий, или тиотропий) или к лактозе.\u003Cbr\u003E \n- Возраст до 18 лет (эффективность и безопасность не установлена).\u003Cbr\u003E \n- Непереносимость галактозы, дефицит лактазы или глюкозо-галактозная мальабсорбция (препарат содержит лактозу)."},{"name":"Состав","value":"Состав одну дозу:\u003Cbr\u003E\nДействующее вещество: аклидиния бромид микронизированный - 0,400 мг.\u003Cbr\u003E \nВспомогательное вещество: α-лактозы моногидрат - 12,60 мг."},{"name":"Действующее вещество","value":"Аклидиния бромид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["27144131:28710456"]}}},{"name":"Способ применения и дозы","value":"Для ингаляционного применения.\u003Cbr\u003E \nРекомендуемая доза составляет 322 мкг аклидиния (одна ингаляция) два раза в день.\u003Cbr\u003E \nВ случае пропуска приема дозы следующую дозу необходимо принять как можно скорее. Однако в случае, если время для приема следующей дозы (после пропуска) почти подошло, пропущенную дозу принимать не следует."},{"name":"Побочные действия","value":"Наиболее часто встречающимися побочными действиями при применении препарата Бретарис Дженуэйр являются головная боль (6,6%) и назофарингит (5,5%).\u003Cbr\u003E \nЧастота побочных действий основана на оценке общих коэффициентов возникновения побочных действий (то есть событий, связанных с применением препарата Бретарис Дженуэйр), наблюдаемых при применении препарата Бретарис Дженуэйр в дозе 322 мкг (636 пациентов) при пудовом анализе одного 6-месячного и двух 3-х месячных рандомизированных клинических исследований с контролем плацебо.\u003Cbr\u003E \nЧастота побочных действий определена следующим образом: очень часто (≥1/10), часто (от ≥1/100 до \u003C 1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C1/10000); и частота неизвестна (побочные действия, частота возникновения которых неизвестна, т.е. частоту нельзя оценить, исходя из имеющихся данных).\u003Cbr\u003E \nИнфекционные и паразитарные заболевания. Часто: синусит, назофарингит.\u003Cbr\u003E \nНарушения со стороны иммунной системы. Редко: реакции гиперчувствительности; частота неизвестна: ангионевротический отек.\u003Cbr\u003E \nНарушения со стороны нервной системы. Часто: головная боль; нечасто: головокружение.\u003Cbr\u003E \nНарушения со стороны органа зрения. Нечасто: нечеткость зрения.\u003Cbr\u003E \nНарушения со стороны сердечно-сосудистой системы. Нечасто: тахикардия, ощущение сердцебиения.\u003Cbr\u003E \nНарушения со стороны дыхательной системы, органов грудной клетки и средостения. Часто: кашель; нечасто: дисфония.\u003Cbr\u003E \nНарушения со стороны желудочно-кишечного тракта. Часто: диарея; нечасто: сухость слизистой оболочки полости рта, стоматит.\u003Cbr\u003E \nНарушения со стороны кожных покровов и подкожных тканей. Нечасто: сыпь, кожный зуд.\u003Cbr\u003E \nНарушения со стороны почек и мочевыводящих путей. Нечасто: задержка мочи."},{"name":"Фармакологическое действие","value":"Аклидиния бромид является конкурентным, селективным антагонистом мускариновых рецепторов (также называемый антихолинергическим), с более длительным временем связывания с М3 - рецепторами, чем с М2 - рецепторами. М3 рецепторы служат посредниками при сокращении гладкой мускулатуры дыхательных путей. Вдыхаемый аклидиния бромид действует местно в легких, в качестве антагониста М3 - рецепторов гладкой мускулатуры дыхательных путей и вызывает расширение бронхов. Доклинические исследования in vitro и in vivo продемонстрировали быстрое, дозозависимое и длительное ингибирование аклидиния бромидом бронхоспазма, вызванного ацетилхолином. Аклидиния бромид быстро разрушается в плазме, поэтому количество системных антихолинергических побочных действий является низким."},{"name":"Фармакологическая группа","value":"м-холиноблокатор"},{"name":"Форма выпуска","value":"порошок для ингаляций"},{"name":"Способ применения/введения","value":"ингалятивный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["35947170:36763738"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Высокие дозы аклидиния бромида могут приводить к симптомам, связанным с антихолинергическим действием.\u003Cbr\u003E \nОднако, однократная ингаляционная доза аклидиния бромида до 6000 мкг у здоровых добровольцев нс приводила к системным побочным антихолинергическим эффектам. Не отмечалось клинически значимых побочных действий после 7-дневного лечения аклидиния бромидом в дозах до 800 мкг дважды в день у здоровых добровольцев.\u003Cbr\u003E \nРазвитие острой интоксикации при случайной передозировке аклидиния бромидом является маловероятным вследствие низкой биодоступности при приеме внутрь и ингаляционном способе дозирования препарата Бретарис Дженуэйр.\u003Cbr\u003E\nЛечение: симптоматическое."},{"name":"Применение при беременности и кормлении грудью","value":"Нет клинических данных по применению аклидиния бромида у беременных женщин. Доклинические исследования продемонстрировали токсическое действие на плод только в дозах, во много раз превышающих максимальную терапевтическую дозу у человека. Аклидиния бромид может применяться во время беременности только в том случае, если ожидаемая польза для матери превосходит потенциальный риск для плода."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Аклидиния бромид может оказывать влияние на способность к управлению транспортными средствами и другими механизмами. Учитывая возможность развития таких побочных эффектов как головная боль, головокружение, нечеткость зрения, следует соблюдать осторожность при управлении транспортными средствам, другими механизмами, а также при занятиях потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Астма\u003Cbr\u003E \nПрепарат Бретарис Дженуэйр не должен использоваться при астме; клинические исследования по применению аклидиния бромида для лечения астмы не проводились.\u003Cbr\u003E \nПарадоксальный бронхоспазм\u003Cbr\u003E \nКак и при другой ингаляционной терапии, применение препарата Бретарис Дженуэйр может вызывать парадоксальный бронхоспазм. Если это произошло, то лечение препаратом Бретарис Дженуэйр необходимо прекратить и рассмотреть возможность другой терапии.\u003Cbr\u003E \nУсиление симптомов заболевания\u003Cbr\u003E \nАклидиния бромид предназначен для поддерживающего лечения больных с ХОБЛ и не должен использоваться в качестве препарата экстренной терапии. Если во время лечения аклидиния бромидом у пациента произошло изменение выраженности симптомов ХОБЛ, что потребовало проведения дополнительной экстренной терапии, должна быть проведена повторная оценка состояния пациента и пересмотр тактики лечения.\u003Cbr\u003E \nВлияние на сердечно-сосудистую систему\u003Cbr\u003E \nПрофиль безопасности в отношении сердечно-сосудистой системы характеризуется наличием антихолинергического действия.\u003Cbr\u003E \nКак и другие м-холиноблокаторы препарат, препарат Бретарис Дженуэйр следует назначать с осторожностью больным, перенесшим инфаркт миокарда в предшествующие 6 месяцев, с нестабильной стенокардией, впервые диагностированной аритмией в предшествующие 3 месяца, или пациентам, в предшествующие 12 месяцев госпитализированным по поводу сердечной недостаточности III и IV функциональных классов по классификации \"Нью-Йоркской кардиологической ассоциации\", т. к. такие пациенты были исключены из клинических исследований, а антихолинергические эффекты могут оказать влияние на течение указанных заболеваний.\u003Cbr\u003E \nАнтихолинергические эффекты\u003Cbr\u003E \nСухость слизистой оболочки полости рта, наблюдаемая при применение антихолинергических препаратов, с течением времени может быть ассоциирована с развитием кариеса зубов.\u003Cbr\u003E \nВ связи с наличием антихолинергических эффектов, аклидиния бромид следует назначать с осторожностью пациентам с закрытоугольной глаукомой (несмотря на то, что прямой контакт препарата с глазами очень маловероятен), гиперплазией предстательной железы и обструкцией шейки мочевого пузыря. Пациенты должны быть проинформированы о признаках и симптомах острого приступа закрытоугольной глаукомы и о необходимости прекратить применение препарата и обратиться к врачу в случае их появления.\u003Cbr\u003E \nПрепарат Бретарис Дженуэйр предназначен для поддерживающего лечения больных ХОБЛ. В связи с тем обстоятельством, что в общей популяции ХОБЛ существенно преобладают больные в возрасте старше 40 лет, при назначении препарата пациентам до 40 лет требуется спирометрическое подтверждение диагноза ХОБЛ."},{"name":"Взаимодействие","value":"Одновременное применение аклидиния бромида с другими М-холиноблокаторами не изучалось и не рекомендуется.\u003Cbr\u003E\nНесмотря на отсутствие исследований in vivo, применение аклидиния бромида для ингаляций возможно в комбинации с другими лекарственными средствами для терапии ХОБЛ, включая симпатомиметики, бронходилататоры, метилксантины и ингаляционные или пероральные глюкокортикостероиды.\u003Cbr\u003E\nИсследования in vitro продемонстрировали, что аклидиния бромид в терапевтической дозе или его метаболиты не взаимодействуют с лекарственными средствами, являющимися субстратами Р-гликопротеина или лекарственными средствами, которые метаболизируются изоферментами цитохрома Р450 (CYP450) и эстеразами."},{"name":"Регистрационный номер","value":"ЛП-003216"},{"name":"Дата государственной регистрации","value":"13.06.2017"},{"name":"Владелец регистрационного удостоверения","value":"AstraZeneca","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["34324371:35649313","7893318:16002703"]}}},{"name":"Изготовитель","value":"Almirall"},{"name":"Страна бренда","value":"Великобритания"},{"name":"Страна-производитель","value":"Испания"},{"name":"Название препарата","value":"Бретарис Дженуэйр","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["17796364:18053335"]}}},{"name":"Срок годности","value":"23 мес."}]}},"fullSpecsGrouped":{"15661926898143353328":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"дыхательная система"},{"name":"Назначение","value":"хроническая обструктивная болезнь легких"},{"name":"Показания к применению","value":"Препарат Бретарис Дженуэйр предназначен для поддерживающей бронходилатирующей терапии с целью облегчения симптомов хронической обструктивной болезни легких (ХОБЛ) у взрослых."},{"name":"Противопоказания","value":"- Повышенная чувствительность к аклидиния бромиду, атропину и его производным (ипратропий, окситропий, или тиотропий) или к лактозе.\u003Cbr\u003E \n- Возраст до 18 лет (эффективность и безопасность не установлена).\u003Cbr\u003E \n- Непереносимость галактозы, дефицит лактазы или глюкозо-галактозная мальабсорбция (препарат содержит лактозу)."},{"name":"Состав","value":"Состав одну дозу:\u003Cbr\u003E\nДействующее вещество: аклидиния бромид микронизированный - 0,400 мг.\u003Cbr\u003E \nВспомогательное вещество: α-лактозы моногидрат - 12,60 мг."},{"name":"Действующее вещество","value":"Аклидиния бромид"},{"name":"Способ применения и дозы","value":"Для ингаляционного применения.\u003Cbr\u003E \nРекомендуемая доза составляет 322 мкг аклидиния (одна ингаляция) два раза в день.\u003Cbr\u003E \nВ случае пропуска приема дозы следующую дозу необходимо принять как можно скорее. Однако в случае, если время для приема следующей дозы (после пропуска) почти подошло, пропущенную дозу принимать не следует."},{"name":"Побочные действия","value":"Наиболее часто встречающимися побочными действиями при применении препарата Бретарис Дженуэйр являются головная боль (6,6%) и назофарингит (5,5%).\u003Cbr\u003E \nЧастота побочных действий основана на оценке общих коэффициентов возникновения побочных действий (то есть событий, связанных с применением препарата Бретарис Дженуэйр), наблюдаемых при применении препарата Бретарис Дженуэйр в дозе 322 мкг (636 пациентов) при пудовом анализе одного 6-месячного и двух 3-х месячных рандомизированных клинических исследований с контролем плацебо.\u003Cbr\u003E \nЧастота побочных действий определена следующим образом: очень часто (≥1/10), часто (от ≥1/100 до \u003C 1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C1/10000); и частота неизвестна (побочные действия, частота возникновения которых неизвестна, т.е. частоту нельзя оценить, исходя из имеющихся данных).\u003Cbr\u003E \nИнфекционные и паразитарные заболевания. Часто: синусит, назофарингит.\u003Cbr\u003E \nНарушения со стороны иммунной системы. Редко: реакции гиперчувствительности; частота неизвестна: ангионевротический отек.\u003Cbr\u003E \nНарушения со стороны нервной системы. Часто: головная боль; нечасто: головокружение.\u003Cbr\u003E \nНарушения со стороны органа зрения. Нечасто: нечеткость зрения.\u003Cbr\u003E \nНарушения со стороны сердечно-сосудистой системы. Нечасто: тахикардия, ощущение сердцебиения.\u003Cbr\u003E \nНарушения со стороны дыхательной системы, органов грудной клетки и средостения. Часто: кашель; нечасто: дисфония.\u003Cbr\u003E \nНарушения со стороны желудочно-кишечного тракта. Часто: диарея; нечасто: сухость слизистой оболочки полости рта, стоматит.\u003Cbr\u003E \nНарушения со стороны кожных покровов и подкожных тканей. Нечасто: сыпь, кожный зуд.\u003Cbr\u003E \nНарушения со стороны почек и мочевыводящих путей. Нечасто: задержка мочи."},{"name":"Фармакологическое действие","value":"Аклидиния бромид является конкурентным, селективным антагонистом мускариновых рецепторов (также называемый антихолинергическим), с более длительным временем связывания с М3 - рецепторами, чем с М2 - рецепторами. М3 рецепторы служат посредниками при сокращении гладкой мускулатуры дыхательных путей. Вдыхаемый аклидиния бромид действует местно в легких, в качестве антагониста М3 - рецепторов гладкой мускулатуры дыхательных путей и вызывает расширение бронхов. Доклинические исследования in vitro и in vivo продемонстрировали быстрое, дозозависимое и длительное ингибирование аклидиния бромидом бронхоспазма, вызванного ацетилхолином. Аклидиния бромид быстро разрушается в плазме, поэтому количество системных антихолинергических побочных действий является низким."},{"name":"Фармакологическая группа","value":"м-холиноблокатор"},{"name":"Форма выпуска","value":"порошок для ингаляций"},{"name":"Способ применения/введения","value":"ингалятивный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Высокие дозы аклидиния бромида могут приводить к симптомам, связанным с антихолинергическим действием.\u003Cbr\u003E \nОднако, однократная ингаляционная доза аклидиния бромида до 6000 мкг у здоровых добровольцев нс приводила к системным побочным антихолинергическим эффектам. Не отмечалось клинически значимых побочных действий после 7-дневного лечения аклидиния бромидом в дозах до 800 мкг дважды в день у здоровых добровольцев.\u003Cbr\u003E \nРазвитие острой интоксикации при случайной передозировке аклидиния бромидом является маловероятным вследствие низкой биодоступности при приеме внутрь и ингаляционном способе дозирования препарата Бретарис Дженуэйр.\u003Cbr\u003E\nЛечение: симптоматическое."},{"name":"Применение при беременности и кормлении грудью","value":"Нет клинических данных по применению аклидиния бромида у беременных женщин. Доклинические исследования продемонстрировали токсическое действие на плод только в дозах, во много раз превышающих максимальную терапевтическую дозу у человека. Аклидиния бромид может применяться во время беременности только в том случае, если ожидаемая польза для матери превосходит потенциальный риск для плода."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Аклидиния бромид может оказывать влияние на способность к управлению транспортными средствами и другими механизмами. Учитывая возможность развития таких побочных эффектов как головная боль, головокружение, нечеткость зрения, следует соблюдать осторожность при управлении транспортными средствам, другими механизмами, а также при занятиях потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Астма\u003Cbr\u003E \nПрепарат Бретарис Дженуэйр не должен использоваться при астме; клинические исследования по применению аклидиния бромида для лечения астмы не проводились.\u003Cbr\u003E \nПарадоксальный бронхоспазм\u003Cbr\u003E \nКак и при другой ингаляционной терапии, применение препарата Бретарис Дженуэйр может вызывать парадоксальный бронхоспазм. Если это произошло, то лечение препаратом Бретарис Дженуэйр необходимо прекратить и рассмотреть возможность другой терапии.\u003Cbr\u003E \nУсиление симптомов заболевания\u003Cbr\u003E \nАклидиния бромид предназначен для поддерживающего лечения больных с ХОБЛ и не должен использоваться в качестве препарата экстренной терапии. Если во время лечения аклидиния бромидом у пациента произошло изменение выраженности симптомов ХОБЛ, что потребовало проведения дополнительной экстренной терапии, должна быть проведена повторная оценка состояния пациента и пересмотр тактики лечения.\u003Cbr\u003E \nВлияние на сердечно-сосудистую систему\u003Cbr\u003E \nПрофиль безопасности в отношении сердечно-сосудистой системы характеризуется наличием антихолинергического действия.\u003Cbr\u003E \nКак и другие м-холиноблокаторы препарат, препарат Бретарис Дженуэйр следует назначать с осторожностью больным, перенесшим инфаркт миокарда в предшествующие 6 месяцев, с нестабильной стенокардией, впервые диагностированной аритмией в предшествующие 3 месяца, или пациентам, в предшествующие 12 месяцев госпитализированным по поводу сердечной недостаточности III и IV функциональных классов по классификации \"Нью-Йоркской кардиологической ассоциации\", т. к. такие пациенты были исключены из клинических исследований, а антихолинергические эффекты могут оказать влияние на течение указанных заболеваний.\u003Cbr\u003E \nАнтихолинергические эффекты\u003Cbr\u003E \nСухость слизистой оболочки полости рта, наблюдаемая при применение антихолинергических препаратов, с течением времени может быть ассоциирована с развитием кариеса зубов.\u003Cbr\u003E \nВ связи с наличием антихолинергических эффектов, аклидиния бромид следует назначать с осторожностью пациентам с закрытоугольной глаукомой (несмотря на то, что прямой контакт препарата с глазами очень маловероятен), гиперплазией предстательной железы и обструкцией шейки мочевого пузыря. Пациенты должны быть проинформированы о признаках и симптомах острого приступа закрытоугольной глаукомы и о необходимости прекратить применение препарата и обратиться к врачу в случае их появления.\u003Cbr\u003E \nПрепарат Бретарис Дженуэйр предназначен для поддерживающего лечения больных ХОБЛ. В связи с тем обстоятельством, что в общей популяции ХОБЛ существенно преобладают больные в возрасте старше 40 лет, при назначении препарата пациентам до 40 лет требуется спирометрическое подтверждение диагноза ХОБЛ."},{"name":"Взаимодействие","value":"Одновременное применение аклидиния бромида с другими М-холиноблокаторами не изучалось и не рекомендуется.\u003Cbr\u003E\nНесмотря на отсутствие исследований in vivo, применение аклидиния бромида для ингаляций возможно в комбинации с другими лекарственными средствами для терапии ХОБЛ, включая симпатомиметики, бронходилататоры, метилксантины и ингаляционные или пероральные глюкокортикостероиды.\u003Cbr\u003E\nИсследования in vitro продемонстрировали, что аклидиния бромид в терапевтической дозе или его метаболиты не взаимодействуют с лекарственными средствами, являющимися субстратами Р-гликопротеина или лекарственными средствами, которые метаболизируются изоферментами цитохрома Р450 (CYP450) и эстеразами."},{"name":"Регистрационный номер","value":"ЛП-003216"},{"name":"Дата государственной регистрации","value":"13.06.2017"},{"name":"Владелец регистрационного удостоверения","value":"AstraZeneca"},{"name":"Изготовитель","value":"Almirall"},{"name":"Страна бренда","value":"Великобритания"},{"name":"Страна-производитель","value":"Испания"},{"name":"Название препарата","value":"Бретарис Дженуэйр"},{"name":"Срок годности","value":"23 мес."}]}],"transitionId":"tr_13548157507400870493"}}}}
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    Цена 1 922 ₽
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  • Спиолто респимат р-р д/ин.г. дозир., 2.5 мкг+2.5 мкг/доза, 4 мл
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    Спиолто респимат р-р д/ин.г. дозир., 2.5 мкг+2.5 мкг/доза, 4 мл

    Рейтинг товара: 4.9 из 5
    на основе 9 оценок
    Цена 3 096 ₽
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  • Атровент Н аэроз. д/ингал. дозир., 20 мкг/доза, 10 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xteerkmm7xl/toggleWishlist":{"skuId":"228018695","productId":1778174483,"offerId":"4AMgojRhTZ43Cqqv23op-Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ8O+4z66N44kJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIk5TzzwYQh5TdbBjGtN4HIOHcwQc=","sign":"4sCsSjCEBy+bj9iDa2+YTugcgvOVcvOz3uwnBw8pOyA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xteerkmm7xl/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Атровент Н аэроз. д/ингал. дозир., 20 мкг/доза, 10 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 317 ₽
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  • Ультибро Бризхалер капс. с пор. д/инг. с устр. д/ингаляций (бризхалер), 50 мкг+110 мкг, 30 шт.
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    Ультибро Бризхалер капс. с пор. д/инг. с устр. д/ингаляций (бризхалер), 50 мкг+110 мкг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 8 оценок
    Цена 3 047 ₽
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  • Симбикорт турбухалер пор. д/инг. дозир., 80 мкг+4.5 мкг/доза, 60 шт.
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    Симбикорт турбухалер пор. д/инг. дозир., 80 мкг+4.5 мкг/доза, 60 шт.

    Рейтинг товара: 4.8 из 5
    на основе 42 оценки
    Цена 1 114 ₽
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  • Кромоспир аэр. д/инг. дозир. балл., 5 мг/доза, 112 шт.
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    Кромоспир аэр. д/инг. дозир. балл., 5 мг/доза, 112 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 679 ₽
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  • Астмасол-нео аэрозоль д/инг. дозир., 20 мкг+50 мкг/доза, 200 шт.
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    Астмасол-нео аэрозоль д/инг. дозир., 20 мкг+50 мкг/доза, 200 шт.

    Рейтинг товара: 5 из 5
    на основе 6 оценок
    Цена 449 ₽
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  • Беротек Н аэр. д/инг. дозир., 100 мкг/доза, 10 мл, 1 шт.
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    Беротек Н аэр. д/инг. дозир., 100 мкг/доза, 10 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 657 ₽
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  • Респирафен Эйр аэр. д/инг. дозир., 20 мкг/доза+50 мкг/доза
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    Респирафен Эйр аэр. д/инг. дозир., 20 мкг/доза+50 мкг/доза

    Рейтинг товара: 4.7 из 5
    на основе 3 оценки
    Цена 522 ₽
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  • Брезтри Аэросфера аэр. д/инг. дозир., 160 мкг+7.2 мкг+5 мкг/доза, 120 шт.
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    Брезтри Аэросфера аэр. д/инг. дозир., 160 мкг+7.2 мкг+5 мкг/доза, 120 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 4 879 ₽
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  • Фостер аэр. д/инг. дозир., 100 мкг+6 мкг/доза, 1 шт.
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    Фостер аэр. д/инг. дозир., 100 мкг+6 мкг/доза, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 19 оценок
    Цена 2 317 ₽
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Инструкция

Показания к применению

Препарат Бретарис Дженуэйр предназначен для поддерживающей бронходилатирующей терапии с целью облегчения симптомов хронической обструктивной болезни легких (ХОБЛ) у взрослых.

Противопоказания

- Повышенная чувствительность к аклидиния бромиду, атропину и его производным (ипратропий, окситропий, или тиотропий) или к лактозе.
- Возраст до 18 лет (эффективность и безопасность не установлена).
- Непереносимость галактозы, дефицит лактазы или глюкозо-галактозная мальабсорбция (препарат содержит лактозу).

Способ применения и дозы

Для ингаляционного применения.
Рекомендуемая доза составляет 322 мкг аклидиния (одна ингаляция) два раза в день.
В случае пропуска приема дозы следующую дозу необходимо принять как можно скорее. Однако в случае, если время для приема следующей дозы (после пропуска) почти подошло, пропущенную дозу принимать не следует.
Полная инструкция
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Бретарис Дженуэйр пор. д/инг. дозир.
Бретарис Дженуэйр пор. д/инг. дозир., 322 мкг/доза, 60 шт.
3.7
(3)
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1 вопрос
Инструкция

2 346 ₽

Скидка: 11%
–11 %
Вместо:2 635 ₽
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3.7
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У продавца:3 оценки·1 отзыв
У всех продавцов:12 оценок·2 отзыва
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user avatar
10 месяцев назад • Владимир Е. • Куплен на Маркете
Комментарий: ок
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