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Зодак капли д/вн. приема, 10 мг/мл, 20 мл

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Коротко о товаре

Артикул Маркета
3123150701
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 месяцев
Инструкция
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вещество","value":"Цетиризин","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["27144131:28708921"]}}},{"name":"Возраст","value":"От 6 месяцев"},{"name":"Форма выпуска","value":"Капли"}]}},"fullSpecs":{"2620605082814469278":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34324371:35649313"]}}},{"name":"Органы и системы","value":"глаза, кожа, носовая полость","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34045610:34516019,34516013,34516012"]}}},{"name":"Назначение","value":"аллергический конъюнктивит, аллергический ринит, крапивница","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["36476390:36618607,36618007,36617672"]}}},{"name":"Показания к применению","value":"Применение препарата показано у взрослых и детей с 6 месяцев для облегчения:\u003Cbr\u003E- назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы;\u003Cbr\u003E- симптомов хронической идиопатической крапивницы.\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!"},{"name":"Противопоказания","value":"Повышенная чувствительность к цетиризину, гидроксизину или другим производным пиперазина, а также любому другому компоненту препарата;\u003Cbr\u003E- терминальная стадия почечной недостаточности (клиренс креатинина \u003C10 мл/мин);\u003Cbr\u003E- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности применения)."},{"name":"Состав","value":"1 мл содержит:\u003Cbr\u003Eактивное вещество:\u003Cbr\u003Eцетиризина дигидрохлорид 10 мг\u003Cbr\u003Eвспомогательные вещества:\u003Cbr\u003EМетилпарагидроксибензоат, пропилпаагидроксибензоат, глицерол, пропиленгликоль, натрия сахарида дигидрат, натрия ацетат тригидрат, уксусная кислота ледяная, вода очищенная."},{"name":"Действующее вещество","value":"Цетиризин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["27144131:28708921"]}}},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПринимать препарат следует вечером, т.к. симптомы становятся более выраженными вечером.\u003Cbr\u003EПри необходимости препарат Зодак можно запить стаканом воды.\u003Cbr\u003EПрепарат Зодак можно принимать независимо от приёма пищи.\u003Cbr\u003EВзрослым\u003Cbr\u003E10 мг (20 капель) 1 раз в день.\u003Cbr\u003EАльтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).\u003Cbr\u003EДети\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!\u003Cbr\u003EДети от 6 до 12 месяцев\u003Cbr\u003E2,5 мг (5 капель) 1 раз в день.\u003Cbr\u003EДети от 1 года до 6 лет\u003Cbr\u003E2,5 мг (5 капель) 2 раза в день утром и вечером\u003Cbr\u003EПродолжительность лечения не должна превышать 4 недель.\u003Cbr\u003EДети от 6 до 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день\u003Cbr\u003EПродолжительность лечения не должна превышать 4 недель.\u003Cbr\u003EАльтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).\u003Cbr\u003EДети старше 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день\u003Cbr\u003EИногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.\u003Cbr\u003EДетям с почечной недостаточностью дозу корректируют с учетом КК и массы тела."},{"name":"Побочные действия","value":"Частота развития нежелательных явлений определялась следующим образом: очень часто (≥10), часто (≥1/100, \u003C1/10), нечасто (≥1/1000, \u003C1/100), редко (≥ 1/10000, \u003C1/1000), очень редко (\u003C1/10000), частота неизвестна (из-за недостаточности данных).\u003Cbr\u003EНарушения co стороны крови и лимфатической системы:\u003Cbr\u003EОчень редко: тромбоцитопения\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003EРедко: реакция гиперчувствительности\u003Cbr\u003EОчень редко: анафилактический шок\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003EЧастота неизвестна: повышение аппетита\u003Cbr\u003EНарушения психики:\u003Cbr\u003EНечасто: возбуждение\u003Cbr\u003EРедко: агрессия, спутанность сознания, депрессия, галлюцинации\u003Cbr\u003EОчень редко: тик\u003Cbr\u003EЧастота неизвестна: суицидальные идеи, нарушения сна (включая кошмарные сновидения)\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EНечасто: парестезии\u003Cbr\u003EРедко: судороги\u003Cbr\u003EОчень редко: извращение вкусов, дисгевзия, дистония, обморок, тремор\u003Cbr\u003EЧастота неизвестна: нарушение памяти, в том числе амнезия, глухота\u003Cbr\u003EНарушения со стороны органа зрения\u003Cbr\u003EОчень редко: нарушение аккомодации, нечеткость зрения, нистагм\u003Cbr\u003EЧастота неизвестна: васкулит\u003Cbr\u003EНарушения со стороны органов слуха и лабиринтные нарушения\u003Cbr\u003EЧастота неизвестна: вертиго\u003Cbr\u003EНарушения со стороны сердца\u003Cbr\u003EРедко: тахикардия\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003EНечасто: диарея\u003Cbr\u003EНарушения со стороны печени и желчевыводящих протоков\u003Cbr\u003EРедко: печеночная недостаточность с изменением функциональных печеночных проб (повышение активности трансаминаз, щелочной фосфатазы, гамма-глутамилтрансферазы и билирубина)\u003Cbr\u003EЧастота неизвестна: гепатит\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EНечасто: сыпь, зуд\u003Cbr\u003EРедко: крапивница\u003Cbr\u003EОчень редко: ангионевротический отек, стойкая лекарственная эритема\u003Cbr\u003EЧастота неизвестна: острый генерализованный экзантематозный пустулез\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003EОчень редко: дизурия, энурез\u003Cbr\u003EЧастота неизвестна: задержка мочи\u003Cbr\u003EНарушения со стороны скелетно-мышечной системы и соединительной\u003Cbr\u003EТкани:\u003Cbr\u003EЧастота неизвестна: артралгия\u003Cbr\u003EОбщие расстройства\u003Cbr\u003EНечасто: астения, недомогание\u003Cbr\u003EРедко: периферические отеки\u003Cbr\u003EВлияние на результаты лабораторных и инструментальных исследовании\u003Cbr\u003EРедко: повышение массы тела\u003Cbr\u003EОписание отдельных нежелательных реакций\u003Cbr\u003EПосле прекращения применения цетиризина были отмечены случаи зуда, в том числе интенсивного зуда и/или крапивницы.\u003Cbr\u003EЕсли у Вас отмечаются побочные эффекты, указанные в инструкции или они усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Фармакодинамические свойства\u003Cbr\u003EМеханизм действия\u003Cbr\u003EЦетиризин - активное вещество препарата Зодак - является метаболитом гидроксизина, обладает антигистаминным эффектом с противоаллергическим действием. Цетиризин относится к группе конкурентных антагонистов гистамина и блокирует H1-гистаминовые рецепторы с небольшим воздействием на другие рецепторы и практически не оказывает антихолинергического и антисеротонинового действия.\u003Cbr\u003EЦетиризин оказывает влияние на гистаминзависимую стадию аллергических реакций немедленного действия, а также уменьшает миграцию эозинофилов и ограничивает высвобождение медиаторов при аллергических реакциях замедленного типа. Практически не проходит через гематоэнцефалический барьер и, следовательно, почти не способен достичь центральных рецепторов H1.\u003Cbr\u003EФармакодинамика\u003Cbr\u003EВ исследованиях влияния гистамина на кожу действие цетиризина в дозе 10 мг начиналось через 1 час, достигало максимума со 2-го по 12-ый час и все еще наблюдалось на статистически значимых уровнях через 24 часа. В дополнении к антигистаминному эффекту цетиризин также обладает противовоспалительным эффектом и тем самым оказывает влияние на позднюю фазу аллергической реакции:\u003Cbr\u003E- При дозе 10 мг один или два раза в день, ингибирует позднюю фазу агрегации эозинофилов в коже;\u003Cbr\u003E- При дозе 30 мг в день, ингибирует выведение эозинофилов в бронхиальную альвеолярную жидкость после вызванного аллергеном бронхиального сужения;\u003Cbr\u003E- Ингибирует вызванную калликреином позднюю воспалительную реакцию;\u003Cbr\u003E- Подавляет экпрессию маркеров воспаления, таких как ICAM-1 или VCAM-1;\u003Cbr\u003E- Ингибирует гистаминолибераторов, таких как PAF или субстанция Р.\u003Cbr\u003EВ клинических исследованиях показано, что цетиризин начинает действовать через 20 минут после приема, его эффект сохраняется до 24 часов."},{"name":"Фармакологическая группа","value":"H1-антигистаминные средства"},{"name":"Форма выпуска","value":"капли"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 6 месяцев"},{"name":"Продолжительность действия","value":"24 часа"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25° С.\u003Cbr\u003EХранить в недоступном для детей месте!"},{"name":"Передозировка","value":"Симптомы, наблюдаемые после явной передозировки препараты, влияли на центральную нервную систему или были связаны с возможным антихолинергическим эффектом. Симптомы, которые наблюдались после приема по меньшей мере пятикратного количества рекомендуемой суточной дозы, включали следующее: спутанность сознания, диарея, утомляемость, головная боль, недомогание, мидриаз, зуд, беспокойство, седативный эффект, сонливость, ступор, тахикардия, тремор, задержка мочи.\u003Cbr\u003EЛечение:\u003Cbr\u003EСпецифического антидота нет.\u003Cbr\u003EВ случае передозировки рекомендуется симптоматическое или поддерживающее лечение. Промывание желудка и/или приём активированного угля может быть эффективным, если передозировка произошла недавно. Цетиризин частично выводится при диализе."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EДанные по применению цетиризина во время беременности ограничены (300-1000 исходов беременности). Однако не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью. Экспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и постнатальное развитие.\u003Cbr\u003EПри беременности назначение цетиризина возможно после консультации с врачом, в случае если предполагаемая польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EНе следует применять цетиризин во время грудного вскармливания, т.к. цетиризин экскретируется с грудным молоком.\u003Cbr\u003EВ период грудного вскармливания применение после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для ребенка.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии на фертильность человека ограничены, однако отрицательного влияния на фертильность в исследованиях на животных не выявлено. Перед применением препарата, если Вы беременны, или предполагаете, что Вы могли бы быть беременной, или планируете беременность, необходимо проконсультироваться с врачом."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Цетиризин может привести к повышенной сонливости, следовательно, препарат Зодак может оказывать влияние на способность управлять транспортными средствами, механизмами."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003E- Хроническая почечная недостаточность (при клиренсе креатинина \u003E 10 мл в мин требуется коррекция режима дозирования);\u003Cbr\u003E- пациенты пожилого возраста (при возрастном снижении клубочковой фильтрации); эпилепсия и пациенты с повышенной судорожной готовностью;\u003Cbr\u003E- пациенты с предрасполагающими факторами к задержке мочи (см. раздел \"Особые указания\");\u003Cbr\u003E- детский возраст до 1 года;\u003Cbr\u003E- при одновременном употреблении с алкоголем (см. раздел \"Взаимодействие с другими лекарственными средствами\");\u003Cbr\u003E- период грудного вскармливания;\u003Cbr\u003E- беременность.\u003Cbr\u003EВвиду потенциального угнетающего влияния на центральную нервную систему следует соблюдать осторожность при назначении препарата Зодак® детям в возрасте от 6 мес до 1 года при наличии следующих факторов риска возникновения синдрома внезапной детской смерти, таких, как (но не ограничиваясь этим списком):\u003Cbr\u003E- синдром апноэ во сне или синдром внезапной детской смерти детей грудного возраста у брата или сестры;\u003Cbr\u003E- злоупотребление матери наркотиками или курением во время беременности;\u003Cbr\u003E- молодой возраст матери (19 лет и моложе);\u003Cbr\u003E- злоупотребление курением няни, ухаживающей за ребенком (одна пачка сигарет в день или более);\u003Cbr\u003E- дети, регулярно засыпающие лицом вниз и которых не укладывают на спину;\u003Cbr\u003E- недоношенные (гестационный возраст менее 37 недель) или рожденные с недостаточной массой тела (ниже 10-го перцентиля от гестационного возраста) дети;\u003Cbr\u003E- при совместном приеме препаратов, оказывающих угнетающее влияние на центральную нервную систему.\u003Cbr\u003EВ состав препарата входят вспомогательные вещества метилпарагидрокисбензоат и пропилпарагидроксибензоат, которые могут вызвать аллергические реакции, в том числе замедленного типа.\u003Cbr\u003EУ пациентов с повреждением спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов при задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи.\u003Cbr\u003EУ пациентов с почечной недостаточностью режим дозирования препарата следует корректрировать (см. раздел \"Способ применения и дозы\")\u003Cbr\u003EИз-за возможного снижения функции почек у пациентов пожилого возраста режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EРекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем, так как цетиризин может привести к повышенной сонливости.\u003Cbr\u003EОсторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что блокаторы H1-гистаминовых рецепторов ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EВнимательно прочтите инструкцию перед тем, как начать применение препарата. Сохраните инструкцию, она может понадобиться вновь. Если у Вас возникли вопросы, обратитесь к врачу. Лекарственное средство, которым Вы лечитесь предназначено лично Вам, и его не следует передавать другим лицам, поскольку оно может причинить им вред даже при наличии тех же симптомов, что и у Вас."},{"name":"Взаимодействие","value":"Одновременное применение с азитромицином, циметидином, эритромицином, кетоконазолом или псевдоэфедрином не влияет на фармакокинетические параметры цетиризина. Фармакокинетических взаимодействий не наблюдалось. Согласно испытаниям in vitro, цетиризин не влияет на эффект связывания белка варфарина.\u003Cbr\u003EОдновременный прием азитромицина, эритромицина, кетоконазола, теофиллина и псевдоэфедрина не выявил существенных изменений в клинических лабораторных показателях, жизненно важных функциях и ЭКГ.\u003Cbr\u003EВ исследовании с одновременным приемом теофиллина (400 мг в день) и цетиризина (20 мг в день) было обнаружено незначительное, но статистически достоверное повышение 24- часовой AUC (площади под кривой) на 19% для цетиризина и на 11% для теофиллина. Кроме того, максимальные уровни в плазме крови увеличились до 7,7% и 6,4% соответственно для цетиризина и теофиллина. Одновременно клиренс цетиризина уменьшился на -16%, а также на - 10% в случае теофиллина, когда цетиризин принимали пациенты, которые ранее получали лечение теофиллином. Тем не менее, предварительное лечение цетиризином не оказало существенного влияния на фармакокинетические параметры теофиллина.\u003Cbr\u003EПосле однократного приема цетиризина в дозе 10 мг эффект алкоголя (0,8 %) значительно не усиливался; статистически значимое взаимодействие с 5 мг диазепама было доказано в одном из 16 психометрических тестов.\u003Cbr\u003EОдновременный прием 10 мг цетиризина в день с глипизидом привел к незначительному снижению показателей глюкозы. Этот эффект не имеет клинического значения. Тем не менее, рекомендуется раздельный прием - глипизид утром и цетиризин вечером.\u003Cbr\u003EСтепень всасывания цетиризина не снижается при одновременном приеме пищи, хотя всасывание замедляется на 1 час.\u003Cbr\u003EВ исследовании с многократным приемом ритонавира (600 мг два раза в день) и цетиризина (10 мг в день) степень экспозиции цетиризина была увеличена примерно на 40%, в то время как, экспозиция ритонавира незначительно изменилась (-11%) вследствие сопутствующего приема цетиризина.\u003Cbr\u003EЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Зодак проконсультируйтесь с врачом."},{"name":"Регистрационный номер","value":"ЛC-000433"},{"name":"Дата государственной регистрации","value":"29.09.2020"},{"name":"Владелец регистрационного удостоверения","value":"Sanofi","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34324371:35649313","7893318:11054136"]}}},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Германия"},{"name":"Название препарата","value":"Зодак","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["17796364:17876245"]}}},{"name":"Срок годности","value":"35 мес."}]}},"fullSpecsGrouped":{"2620605082814469278":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"глаза, кожа, носовая полость"},{"name":"Назначение","value":"аллергический конъюнктивит, аллергический ринит, крапивница"},{"name":"Показания к применению","value":"Применение препарата показано у взрослых и детей с 6 месяцев для облегчения:\u003Cbr\u003E- назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы;\u003Cbr\u003E- симптомов хронической идиопатической крапивницы.\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!"},{"name":"Противопоказания","value":"Повышенная чувствительность к цетиризину, гидроксизину или другим производным пиперазина, а также любому другому компоненту препарата;\u003Cbr\u003E- терминальная стадия почечной недостаточности (клиренс креатинина \u003C10 мл/мин);\u003Cbr\u003E- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности применения)."},{"name":"Состав","value":"1 мл содержит:\u003Cbr\u003Eактивное вещество:\u003Cbr\u003Eцетиризина дигидрохлорид 10 мг\u003Cbr\u003Eвспомогательные вещества:\u003Cbr\u003EМетилпарагидроксибензоат, пропилпаагидроксибензоат, глицерол, пропиленгликоль, натрия сахарида дигидрат, натрия ацетат тригидрат, уксусная кислота ледяная, вода очищенная."},{"name":"Действующее вещество","value":"Цетиризин"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПринимать препарат следует вечером, т.к. симптомы становятся более выраженными вечером.\u003Cbr\u003EПри необходимости препарат Зодак можно запить стаканом воды.\u003Cbr\u003EПрепарат Зодак можно принимать независимо от приёма пищи.\u003Cbr\u003EВзрослым\u003Cbr\u003E10 мг (20 капель) 1 раз в день.\u003Cbr\u003EАльтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).\u003Cbr\u003EДети\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!\u003Cbr\u003EДети от 6 до 12 месяцев\u003Cbr\u003E2,5 мг (5 капель) 1 раз в день.\u003Cbr\u003EДети от 1 года до 6 лет\u003Cbr\u003E2,5 мг (5 капель) 2 раза в день утром и вечером\u003Cbr\u003EПродолжительность лечения не должна превышать 4 недель.\u003Cbr\u003EДети от 6 до 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день\u003Cbr\u003EПродолжительность лечения не должна превышать 4 недель.\u003Cbr\u003EАльтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).\u003Cbr\u003EДети старше 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день\u003Cbr\u003EИногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.\u003Cbr\u003EДетям с почечной недостаточностью дозу корректируют с учетом КК и массы тела."},{"name":"Побочные действия","value":"Частота развития нежелательных явлений определялась следующим образом: очень часто (≥10), часто (≥1/100, \u003C1/10), нечасто (≥1/1000, \u003C1/100), редко (≥ 1/10000, \u003C1/1000), очень редко (\u003C1/10000), частота неизвестна (из-за недостаточности данных).\u003Cbr\u003EНарушения co стороны крови и лимфатической системы:\u003Cbr\u003EОчень редко: тромбоцитопения\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003EРедко: реакция гиперчувствительности\u003Cbr\u003EОчень редко: анафилактический шок\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003EЧастота неизвестна: повышение аппетита\u003Cbr\u003EНарушения психики:\u003Cbr\u003EНечасто: возбуждение\u003Cbr\u003EРедко: агрессия, спутанность сознания, депрессия, галлюцинации\u003Cbr\u003EОчень редко: тик\u003Cbr\u003EЧастота неизвестна: суицидальные идеи, нарушения сна (включая кошмарные сновидения)\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EНечасто: парестезии\u003Cbr\u003EРедко: судороги\u003Cbr\u003EОчень редко: извращение вкусов, дисгевзия, дистония, обморок, тремор\u003Cbr\u003EЧастота неизвестна: нарушение памяти, в том числе амнезия, глухота\u003Cbr\u003EНарушения со стороны органа зрения\u003Cbr\u003EОчень редко: нарушение аккомодации, нечеткость зрения, нистагм\u003Cbr\u003EЧастота неизвестна: васкулит\u003Cbr\u003EНарушения со стороны органов слуха и лабиринтные нарушения\u003Cbr\u003EЧастота неизвестна: вертиго\u003Cbr\u003EНарушения со стороны сердца\u003Cbr\u003EРедко: тахикардия\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003EНечасто: диарея\u003Cbr\u003EНарушения со стороны печени и желчевыводящих протоков\u003Cbr\u003EРедко: печеночная недостаточность с изменением функциональных печеночных проб (повышение активности трансаминаз, щелочной фосфатазы, гамма-глутамилтрансферазы и билирубина)\u003Cbr\u003EЧастота неизвестна: гепатит\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EНечасто: сыпь, зуд\u003Cbr\u003EРедко: крапивница\u003Cbr\u003EОчень редко: ангионевротический отек, стойкая лекарственная эритема\u003Cbr\u003EЧастота неизвестна: острый генерализованный экзантематозный пустулез\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003EОчень редко: дизурия, энурез\u003Cbr\u003EЧастота неизвестна: задержка мочи\u003Cbr\u003EНарушения со стороны скелетно-мышечной системы и соединительной\u003Cbr\u003EТкани:\u003Cbr\u003EЧастота неизвестна: артралгия\u003Cbr\u003EОбщие расстройства\u003Cbr\u003EНечасто: астения, недомогание\u003Cbr\u003EРедко: периферические отеки\u003Cbr\u003EВлияние на результаты лабораторных и инструментальных исследовании\u003Cbr\u003EРедко: повышение массы тела\u003Cbr\u003EОписание отдельных нежелательных реакций\u003Cbr\u003EПосле прекращения применения цетиризина были отмечены случаи зуда, в том числе интенсивного зуда и/или крапивницы.\u003Cbr\u003EЕсли у Вас отмечаются побочные эффекты, указанные в инструкции или они усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Фармакодинамические свойства\u003Cbr\u003EМеханизм действия\u003Cbr\u003EЦетиризин - активное вещество препарата Зодак - является метаболитом гидроксизина, обладает антигистаминным эффектом с противоаллергическим действием. Цетиризин относится к группе конкурентных антагонистов гистамина и блокирует H1-гистаминовые рецепторы с небольшим воздействием на другие рецепторы и практически не оказывает антихолинергического и антисеротонинового действия.\u003Cbr\u003EЦетиризин оказывает влияние на гистаминзависимую стадию аллергических реакций немедленного действия, а также уменьшает миграцию эозинофилов и ограничивает высвобождение медиаторов при аллергических реакциях замедленного типа. Практически не проходит через гематоэнцефалический барьер и, следовательно, почти не способен достичь центральных рецепторов H1.\u003Cbr\u003EФармакодинамика\u003Cbr\u003EВ исследованиях влияния гистамина на кожу действие цетиризина в дозе 10 мг начиналось через 1 час, достигало максимума со 2-го по 12-ый час и все еще наблюдалось на статистически значимых уровнях через 24 часа. В дополнении к антигистаминному эффекту цетиризин также обладает противовоспалительным эффектом и тем самым оказывает влияние на позднюю фазу аллергической реакции:\u003Cbr\u003E- При дозе 10 мг один или два раза в день, ингибирует позднюю фазу агрегации эозинофилов в коже;\u003Cbr\u003E- При дозе 30 мг в день, ингибирует выведение эозинофилов в бронхиальную альвеолярную жидкость после вызванного аллергеном бронхиального сужения;\u003Cbr\u003E- Ингибирует вызванную калликреином позднюю воспалительную реакцию;\u003Cbr\u003E- Подавляет экпрессию маркеров воспаления, таких как ICAM-1 или VCAM-1;\u003Cbr\u003E- Ингибирует гистаминолибераторов, таких как PAF или субстанция Р.\u003Cbr\u003EВ клинических исследованиях показано, что цетиризин начинает действовать через 20 минут после приема, его эффект сохраняется до 24 часов."},{"name":"Фармакологическая группа","value":"H1-антигистаминные средства"},{"name":"Форма выпуска","value":"капли"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 6 месяцев"},{"name":"Продолжительность действия","value":"24 часа"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25° С.\u003Cbr\u003EХранить в недоступном для детей месте!"},{"name":"Передозировка","value":"Симптомы, наблюдаемые после явной передозировки препараты, влияли на центральную нервную систему или были связаны с возможным антихолинергическим эффектом. Симптомы, которые наблюдались после приема по меньшей мере пятикратного количества рекомендуемой суточной дозы, включали следующее: спутанность сознания, диарея, утомляемость, головная боль, недомогание, мидриаз, зуд, беспокойство, седативный эффект, сонливость, ступор, тахикардия, тремор, задержка мочи.\u003Cbr\u003EЛечение:\u003Cbr\u003EСпецифического антидота нет.\u003Cbr\u003EВ случае передозировки рекомендуется симптоматическое или поддерживающее лечение. Промывание желудка и/или приём активированного угля может быть эффективным, если передозировка произошла недавно. Цетиризин частично выводится при диализе."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EДанные по применению цетиризина во время беременности ограничены (300-1000 исходов беременности). Однако не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью. Экспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и постнатальное развитие.\u003Cbr\u003EПри беременности назначение цетиризина возможно после консультации с врачом, в случае если предполагаемая польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EНе следует применять цетиризин во время грудного вскармливания, т.к. цетиризин экскретируется с грудным молоком.\u003Cbr\u003EВ период грудного вскармливания применение после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для ребенка.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии на фертильность человека ограничены, однако отрицательного влияния на фертильность в исследованиях на животных не выявлено. Перед применением препарата, если Вы беременны, или предполагаете, что Вы могли бы быть беременной, или планируете беременность, необходимо проконсультироваться с врачом."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Цетиризин может привести к повышенной сонливости, следовательно, препарат Зодак может оказывать влияние на способность управлять транспортными средствами, механизмами."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003E- Хроническая почечная недостаточность (при клиренсе креатинина \u003E 10 мл в мин требуется коррекция режима дозирования);\u003Cbr\u003E- пациенты пожилого возраста (при возрастном снижении клубочковой фильтрации); эпилепсия и пациенты с повышенной судорожной готовностью;\u003Cbr\u003E- пациенты с предрасполагающими факторами к задержке мочи (см. раздел \"Особые указания\");\u003Cbr\u003E- детский возраст до 1 года;\u003Cbr\u003E- при одновременном употреблении с алкоголем (см. раздел \"Взаимодействие с другими лекарственными средствами\");\u003Cbr\u003E- период грудного вскармливания;\u003Cbr\u003E- беременность.\u003Cbr\u003EВвиду потенциального угнетающего влияния на центральную нервную систему следует соблюдать осторожность при назначении препарата Зодак® детям в возрасте от 6 мес до 1 года при наличии следующих факторов риска возникновения синдрома внезапной детской смерти, таких, как (но не ограничиваясь этим списком):\u003Cbr\u003E- синдром апноэ во сне или синдром внезапной детской смерти детей грудного возраста у брата или сестры;\u003Cbr\u003E- злоупотребление матери наркотиками или курением во время беременности;\u003Cbr\u003E- молодой возраст матери (19 лет и моложе);\u003Cbr\u003E- злоупотребление курением няни, ухаживающей за ребенком (одна пачка сигарет в день или более);\u003Cbr\u003E- дети, регулярно засыпающие лицом вниз и которых не укладывают на спину;\u003Cbr\u003E- недоношенные (гестационный возраст менее 37 недель) или рожденные с недостаточной массой тела (ниже 10-го перцентиля от гестационного возраста) дети;\u003Cbr\u003E- при совместном приеме препаратов, оказывающих угнетающее влияние на центральную нервную систему.\u003Cbr\u003EВ состав препарата входят вспомогательные вещества метилпарагидрокисбензоат и пропилпарагидроксибензоат, которые могут вызвать аллергические реакции, в том числе замедленного типа.\u003Cbr\u003EУ пациентов с повреждением спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов при задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи.\u003Cbr\u003EУ пациентов с почечной недостаточностью режим дозирования препарата следует корректрировать (см. раздел \"Способ применения и дозы\")\u003Cbr\u003EИз-за возможного снижения функции почек у пациентов пожилого возраста режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EРекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем, так как цетиризин может привести к повышенной сонливости.\u003Cbr\u003EОсторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что блокаторы H1-гистаминовых рецепторов ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EВнимательно прочтите инструкцию перед тем, как начать применение препарата. Сохраните инструкцию, она может понадобиться вновь. Если у Вас возникли вопросы, обратитесь к врачу. Лекарственное средство, которым Вы лечитесь предназначено лично Вам, и его не следует передавать другим лицам, поскольку оно может причинить им вред даже при наличии тех же симптомов, что и у Вас."},{"name":"Взаимодействие","value":"Одновременное применение с азитромицином, циметидином, эритромицином, кетоконазолом или псевдоэфедрином не влияет на фармакокинетические параметры цетиризина. Фармакокинетических взаимодействий не наблюдалось. Согласно испытаниям in vitro, цетиризин не влияет на эффект связывания белка варфарина.\u003Cbr\u003EОдновременный прием азитромицина, эритромицина, кетоконазола, теофиллина и псевдоэфедрина не выявил существенных изменений в клинических лабораторных показателях, жизненно важных функциях и ЭКГ.\u003Cbr\u003EВ исследовании с одновременным приемом теофиллина (400 мг в день) и цетиризина (20 мг в день) было обнаружено незначительное, но статистически достоверное повышение 24- часовой AUC (площади под кривой) на 19% для цетиризина и на 11% для теофиллина. Кроме того, максимальные уровни в плазме крови увеличились до 7,7% и 6,4% соответственно для цетиризина и теофиллина. Одновременно клиренс цетиризина уменьшился на -16%, а также на - 10% в случае теофиллина, когда цетиризин принимали пациенты, которые ранее получали лечение теофиллином. Тем не менее, предварительное лечение цетиризином не оказало существенного влияния на фармакокинетические параметры теофиллина.\u003Cbr\u003EПосле однократного приема цетиризина в дозе 10 мг эффект алкоголя (0,8 %) значительно не усиливался; статистически значимое взаимодействие с 5 мг диазепама было доказано в одном из 16 психометрических тестов.\u003Cbr\u003EОдновременный прием 10 мг цетиризина в день с глипизидом привел к незначительному снижению показателей глюкозы. Этот эффект не имеет клинического значения. Тем не менее, рекомендуется раздельный прием - глипизид утром и цетиризин вечером.\u003Cbr\u003EСтепень всасывания цетиризина не снижается при одновременном приеме пищи, хотя всасывание замедляется на 1 час.\u003Cbr\u003EВ исследовании с многократным приемом ритонавира (600 мг два раза в день) и цетиризина (10 мг в день) степень экспозиции цетиризина была увеличена примерно на 40%, в то время как, экспозиция ритонавира незначительно изменилась (-11%) вследствие сопутствующего приема цетиризина.\u003Cbr\u003EЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Зодак проконсультируйтесь с врачом."},{"name":"Регистрационный номер","value":"ЛC-000433"},{"name":"Дата государственной регистрации","value":"29.09.2020"},{"name":"Владелец регистрационного удостоверения","value":"Sanofi"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Германия"},{"name":"Название препарата","value":"Зодак"},{"name":"Срок годности","value":"35 мес."}]}],"transitionId":"tr_14752587034787674876"}}}}
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  • Зодак таб. п/о плен., 10 мг, 30 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-i9gilokn4ej/toggleWishlist":{"skuId":"186887758","productId":1417730422,"offerId":"Ln2B0cUn2WZ3KnY9WPdt_g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07Ddjqeu+9JJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI9rKDpAUQztyOWRj6g4ISINbZwQc=","sign":"eD7AQ7Q6h8d9Hu2ofUmTY8cCdRK9uR2ou5YA5hSsffo="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-i9gilokn4ej/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Зодак таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 45 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 304 ₽ вместо 307
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  • Цетрин таб. п/о плен., 10 мг, 20 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-td5l2sbzzas/toggleWishlist":{"skuId":"228119468","productId":1417730432,"offerId":"9p6ApXvfgPVXnObxT41jlg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07Ddjqeu+9JJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIgLODpAUQrKfjbBjAotUHINbZwQc=","sign":"VC2lAJUrvIQ0OBZJS0DYqtdd3Moo6j+u9OXpWsONhAk="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-td5l2sbzzas/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Цетрин таб. п/о плен., 10 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 146 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 160 ₽ вместо 162
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-td5l2sbzzas/addToCartButton":{"offerId":"9p6ApXvfgPVXnObxT41jlg","skuId":"228119468","pendingCartItem":{"productId":1417730432,"offerId":"9p6ApXvfgPVXnObxT41jlg","showPlaceId":"OTNDnItfwRMjN9MRHuEMMvdIpV5XGBNwfvsC1-iWi9bM77ESZn8RF7eR-6G2-ds9XNwL2xd25WwSWSTjveVfmQutRru52cNfAd_mg9awVGJ8dfDMVhV5_HquBRxWHpjuNo4ceXBzwdF1zBhjSR8-e7sK6RGY7O5ioF7cGAp1gz_8U56jax3UHMm1OpLAaCgINQXx-EF9Nyk7uApOWNzrwcEq_cAkBNs44MuieoDeFWs,","feeShow":"OTNDnItfwRMjN9MRHuEMMvdIpV5XGBNwfvsC1-iWi9bM77ESZn8RF7eR-6G2-ds9XNwL2xd25WwSWSTjveVfmQutRru52cNfAd_mg9awVGJ8dfDMVhV5_HquBRxWHpjuNo4ceXBzwdF1zBhjSR8-e7sK6RGY7O5ioF7cGAp1gz_8U56jax3UHMm1OpLAaCgINQXx-EF9Nyk7uApOWNzrwcEq_cAkBNs44MuieoDeFWs,","skuId":"228119468","shopId":11693184,"price":{"applicablePriceDiscounts":[{"priceWithDiscount":"160","type":"ya-card","totalPercentWithDiscount":1}],"value":"162","currency":"RUR"},"hid":"15756502","name":"Цетрин таб. п/о плен., 10 мг, 20 шт.","label":"lxt8k2t1iho","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":1543318,"key":"img_id778662624770275743.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sf5XWkAbKtkdM9dIKphPVsa42N931lmJkA8ihPmWACvRDpwuUxkacsB_c7amLUgPT8d-I5h9UeRvFzr5t3P8X5z3-DBItU7evJA2n98twK8P3iL4NiVcITT-GDGoJ-CFCI1wn-HdLTrg_Qgn80nbEhp5XNztTObkhabI-mLZmiKfo7KeN1gHbWmqzpKpGrx_UyB1Hv5jU-J-ESOP-Tfo_NrmPLX9SQLhoLvIyTvd4ZK3mu7pTpBK-0DFkL8RhU2Y1EK1qKOk9RkMQhGHr7ZppVyFsmUpJZkfj1Q0yOnoJgoT2gjueCFt63A4D21JeMo3qImbYABe-xSED3w5tCCnUlfN9wX_qutGsQzl-_WwLQClbpv_dErsirchvgDMUG9-kaO1s4nZLxDq9gn7UUpTPNjqzBZ85pepsJS2kDVRL4PX9UxK4TPjgjRJWX6WRp-a1Xfd8xHKe-zKn3UY30jiBOIoOcBpRCzuImEP_A9C-shPIpGvwHDoIDgeoBFUmmj31xWHk4wyG4PwqNZ5f52EFQx_Sot_f4YmrvR-yq-vIr8EEwsMzwMe8oRkfQCYJFJ7RA2tCFwoYW0x9XD5fR21w5dKan_v61y3PvzGEz1XGDZpRgaJiMd4XSzQujnzcLxP5TX2ov4QuQQbNyVmkYWXtYXWVpjo4X4G1T0eBZ_jT2I--Mu5Z59cKWC4_pR1U-Kdp2bTnY2mLtQCuxIKV9dtfPJdN53r2GHCwIMRayvAF4dXCjKAHbiS5XA-5-_M3TO8EmCmotGYXfGivSjqYz1QRrTMv7yj5wytqJsM9gvl4CgGxCbR1aC05B5gzb6daqzphmwTkehJW8YIGg9RSk7LTOtiP7Fe6WrLk_4WOzLfvmWbfaqlxeYTx7MZNKT7fNeW0ACWsLVgLP3Jj_AVyPYllEY8Ic-2gNHJS16Y_fOF-dYOQjqSximA7nEIMmIFcb4UsP4Q95zzoUqq_xCJbuE0JSWx2A5bURoUMreGBjyDmZfcqyUYwVGyO7_8fyKLsAa2eosPNpgMlLNzqkEiMm1vvNU4OGmkN7H8YajcF-d_cdk__ZBdbrR-L0i5Ut5hfZJrYr5IJNsdrOUGtpYQe7UnesFraLCobFr3PbSPoiV6tQS7ICrWW-0mm8F9q2kp5qBRwl89oh1TEg6w1mV4rNw3Wh9X1xqhChldfUjClk6OsKzpCBikSfrQHdzeYRur6wovCWV68fDHJQdHwKjw5k8arDsZzJftyWlLsDBzHt9eW1myqZpbyVBygu-li9myyYpwMejC7yhgIvjghWqlYmE4tguYo6BaNR8HxTas-9KOpvh7K4qkniNlvZZ3GHxdfOUnhsh7ZpK4e-2L2DUpEu8nMzDdN0QRu5qYtUU9oMjggRsmzP1HbI5G2SMhCTJvG4_YJVkxChEMPjTXqhTnUIAD59WTZ42Bv-A7QqxOM-8r7CrocMmZtsAtylAmdVfbo580l0gWQNaGud9K1ZWB50p1FBW-4D8kpb0gXOm16l_XyqmbqxAkZvg6zV5IGv3OiOqbV2XUYLYtBEMlN7jY1OnaByH5KCaSmGPJl14_YT93rueSQjEzqoWtdypDBx55SsHnW6fUIePs6dmmhWJ42YtTuGHsXj1Yi4R2x8M2pEjkOVvHkRMrDLQ0Fo0m9NC7mUyyzKKTQ7PI8XnRSxR3RtD-7ZDILBD_K8Kq4lOuy3htrSE_lqdOJEHw-RFpSyfOCdMPV8L7QSz57m2EJ0zdC34D9i8KXUlBLhLIAKUT9OR8BqWGbAwN4udZDyBl4-Wm5ZFLKk0jInuRfWyvdLpdw0qyyBBhTSoB2U-f6CGPAiIWagBiOqMj9KZgxaFGOkEg1P505KUP_gS_j1Nk9FuSpdYAL2nj0rs5BkWd34VdAZYb_1xagyPtoHWZmI_TlbJJKYbdguoUGG9Ygd-F-be-hF6EsPc1C5NzSg5grgg39U-bxIDUTcJucMe2NNBorr0tL_TgLQspxBTIjAUbBbJ1usT46jlXJ77FMH7LtMF_Hi82dXkonzIc7nEw0qkmYf9ZNULEDF-a_cUGXd86qFtipFl_3_uzT3IOdCO0CKLccEOFST3Xw3jHQJxrvtUQEs5dQn49Efjl4T6TUjbRtyroXwo8rlfNucEybHy9GHdGjHxsX7SlUelrsPDcq16umuaeTckKan97XAi3_2TLULOr3MNfzO-X7fnFzlsX_O0k8LTcM3QgXTvRs_sqlLZzAztP4D3rsoWWdRG1w2xFF7QHAYj9sAHo9r8dE86Q-9euzChfjiXr5u5PeLhstzitax0faE7FB_ysjpY7vS4xGdCfckOFu0lMsO0BNsf88YXLObpKcdYWayfBUfx2Qub-aVpvQ-U_QIN0MxbHt_tdQI9jXTxJ1eG8xS_DkqrCAtA1v1-rqiWtgPvHChb56-C4Y3BiBmh9VIxBOjaFAQhh3KwxeCppz9TzZBHFaFXT3qPlDIgxEit8S4z1xWkWLbLgmwIdi_Va4dHwbRogC8xFyHSDh_YkYNweKGQ4WxjbflC7X2hR0oVO9-PL36lq6lABBjv6EPJRGhS8fUA9e0Z2S4am2Vax1RSHUGXT7L8xsrkN6KGY47ZPtioNU7NIx7-kE6R7s1wTr5jGzjZRz3ck2uI4GrJJT7iB3P87PeQJrCfZv2iL1tO-wWTwIq_rt1ODQhzS9l_u9dU7AfkBuCVO7V89KxEWlb8w9ZGXhfgBJp8hkaBMqocbdq7iWO2_a1lipnzazfNSBdp8MWLXy3T_--yC5MfJsf5UGGI8EWHzqRH4xtNpF6b44yg3gVw7a1AcpCb29YVYMDvVSwppkFriD2l0Rtm0n5q0GqAs6awRmOKwhUTAmJkAfiK7HFGerhHfXK9_S19XG7vetA1DxqyIGeO2gjbBDJy2B7Wl4XUe7wcMJMiy5lZOmugJjC6OqiDiaTYN_6lsd2YvZ9BKqZ_NohD6GsA8P3ZBWaNXw5EzFYTfAiaTemaH1DAQHZq5eUEBkva92H_UoG8FsCTNWjWmrSrf81TrCYqNYx5Z8BNcezV8zPD8CpFoD7Cbz2TYIz_NJvnAt4OyDAbSsQJRFb6ucD8FfiE49XPOaF6VCZ7v7-QMwahKfDGm24rDHLMq7bDx1xqn8UjZLyb6IGYAVLbH2_5wmBcYymzvsjkLt3aD_SvvrtgZ2adm8C1TxehgatyLPonLmmW3A8hnCjcTdDU-e-BqGqdQ7D20lK-4rFgJuZ7u6XnTrsvpTVsuHSdYqJ2HehMTqr1DOfLDilsPAYeaBwp4C5-bd8DWzfbmosczZTZ_KfOx3SM7PuW3ckuJ0QerLYBhgXhpqkOvvZxX7Ec23nFqr8h2AMrS5tj9UAJe-XXj0nld0aj39cnUObt9L1NESwTF4nQIMQGsCIsBkJKzh4euTFj_PkT9zZiidFqj3trDoAF98y1XH64olaMua_G_mfj4uhr-p8mC3ntZlmS0GxvaPtpG4UR2sM4fHiuez6DCm0ylEbzCO7x78h5MwIKN4bKQkOlfaiysTcQwLTaU35MJMqI-Qwfw,,/b64e=1/sign=3bb3818c562800d0ec199e2a322fbc3d/keyno=MARKET_1/*","showUid":"17179905437761070441306002","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07Ddjqeu+9JJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIgLODpAUQrKfjbBjAotUHINbZwQc=","sign":"VC2lAJUrvIQ0OBZJS0DYqtdd3Moo6j+u9OXpWsONhAk="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07Ddjqeu+9JJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIgLODpAUQrKfjbBjAotUHINbZwQc=","sign":"VC2lAJUrvIQ0OBZJS0DYqtdd3Moo6j+u9OXpWsONhAk="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-td5l2sbzzas/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Зодак таб. п/о плен., 10 мг, 10 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-aj2xqi16oz/toggleWishlist":{"skuId":"102268266997","productId":1915017206,"offerId":"6vyTeGbc6m_cLb85XtXdqg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07Ddjqeu+9JJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI9q+TkQcQ9dOn/fwCGMnL9Qcg1tnBBw==","sign":"4wdC0ROqmJ7qVMzjAZ/lVf3OOqNs4JJdhvYtMUy/664="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-aj2xqi16oz/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Зодак таб. п/о плен., 10 мг, 10 шт.

    Рейтинг товара: 4.6 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 122 ₽ вместо 123
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таб. п/о плен., 10 мг, 10 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  • Зиртек капли д/вн. приема, 10 мг/мл, 20 мл
    –1 %
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    Зиртек капли д/вн. приема, 10 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 36 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 172 ₽ вместо 174
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  • Зодак таб. п/о плен., 10 мг, 10 шт.
    –1 %
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    Зодак таб. п/о плен., 10 мг, 10 шт.

    Рейтинг товара: 4.9 из 5
    на основе 27 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 123 ₽ вместо 124
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таб. п/о плен., 10 мг, 10 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  • Фенистил капли д/вн. приема, 0.1%, 20 мл
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vcsv6dcae7/toggleWishlist":{"skuId":"228204900","productId":1778170162,"offerId":"uWMG8h0rINHwsb6iBv5axw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ07Ddjqeu+9JJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIsvLyzwYQ5MLobBjZ3tYFINbZwQc=","sign":"NDtYMss4GhWvTb5WWOdf37IXisvIEu/GEtGUHu9P07c="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vcsv6dcae7/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Фенистил капли д/вн. приема, 0.1%, 20 мл

    Рейтинг товара: 4.8 из 5
    на основе 20 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 577 ₽ вместо 583
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  • Супрастинекс капли д/вн. приема фл., 5 мг/мл, 20 мл
    –1 %
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    Супрастинекс капли д/вн. приема фл., 5 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 414 ₽ вместо 418
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  • Зиртек таб. п/о плен., 10 мг, 30 шт.
    –1 %
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    Зиртек таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 22 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 291 ₽ вместо 294
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  • Цетиризин капли д/вн. приема, 10 мг/мл, 10 мл
    –1 %
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    Цетиризин капли д/вн. приема, 10 мг/мл, 10 мл

    Рейтинг товара: 4.2 из 5
    на основе 10 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 105 ₽ вместо 106
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  • Супрастин таб., 25 мг, 1 мл, 20 шт.
    –1 %
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    Супрастин таб., 25 мг, 1 мл, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 95 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 130 ₽ вместо 131
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{"widgets":{"@light/ScrollBoxControls":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/controls":{"parentId":"7iq9sz6s8do","itemsCount":10,"ratio":[2,13],"withScrollBoxGap":false,"gapWidth":4,"rightButtonOffset":0,"leftButtonOffset":0}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/controls":{"name":"@light/ScrollBoxControls"}}}

Инструкция

Показания к применению

Применение препарата показано у взрослых и детей с 6 месяцев для облегчения:
- назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы;
- симптомов хронической идиопатической крапивницы.
Применение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!

Противопоказания

Повышенная чувствительность к цетиризину, гидроксизину или другим производным пиперазина, а также любому другому компоненту препарата;
- терминальная стадия почечной недостаточности (клиренс креатинина <10 мл/мин);
- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности применения).

Способ применения и дозы

Внутрь.
Принимать препарат следует вечером, т.к. симптомы становятся более выраженными вечером.
При необходимости препарат Зодак можно запить стаканом воды.
Препарат Зодак можно принимать независимо от приёма пищи.
Взрослым
10 мг (20 капель) 1 раз в день.
Альтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).
Дети
Применение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!
Дети от 6 до 12 месяцев
2,5 мг (5 капель) 1 раз в день.
Дети от 1 года до 6 лет
2,5 мг (5 капель) 2 раза в день утром и вечером
Продолжительность лечения не должна превышать 4 недель.
Дети от 6 до 12 лет
10 мг (20 капель) 1 раз в день
Продолжительность лечения не должна превышать 4 недель.
Альтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).
Дети старше 12 лет
10 мг (20 капель) 1 раз в день
Иногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.
Детям с почечной недостаточностью дозу корректируют с учетом КК и массы тела.
Полная инструкция
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Зодак капли д/вн. приема
Зодак капли д/вн. приема, 10 мг/мл, 20 мл
5.0
(29)
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4 вопроса
Инструкция

Цена с картой Яндекс Пэй:157 ₽

Скидка: 25%
–25 %
Вместо: 159 ₽209 ₽
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5.0
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У продавца:29 оценок·3 отзыва
У всех продавцов:185 оценок·51 отзыв
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Месяц назад • Miry Mir • Куплен на Маркете
Достоинства: Помогает
Недостатки: нет
Комментарий: единственный препарат от аллергии,после приема которого меня не клонит в сон.
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4 дня назад • Ксения Шишова • Куплен на Маркете
Достоинства: Как в описании
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2 месяца назад • Шоира Раджабова • Куплен на Маркете
Достоинства: хороший
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