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Описание

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Моксонидин-СЗ таб. п/о плен., 0.2 мг, 60 шт.

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4.7
(18)
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Дозировка: 0.2 мг

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Количество штук в упаковке, шт.: 60

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Коротко о товаре

Артикул Маркета
3123235553
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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;\u003Cbr\u003E- выраженная брадикардия (частота сердечных сокращений покоя менее 50 уд/мин); ;\u003Cbr\u003E- атриовентрикулярная блокада II и III степени; ;\u003Cbr\u003E- выраженные нарушения ритма сердца; ;\u003Cbr\u003E- острая и хроническая сердечная недостаточность (III-IV функциональный класс по классификации NYHA); ;\u003Cbr\u003E- одновременное применение с трициклическими антидепрессантами (см. раздел \"Взаимодействие с другими лекарственными препаратами\");;\u003Cbr\u003E- тяжелая почечная недостаточность (КК менее 30 мл/мин); ;\u003Cbr\u003E- гемодиализ; ;\u003Cbr\u003E- период лактации; ;\u003Cbr\u003E- наследственная непереносимость лактозы, дефицит лактазы или мальабсорбция глюкозы-галактозы; ;\u003Cbr\u003E- возраст старше 75 лет; ;\u003Cbr\u003E- возраст до 18 лет (в связи с отсутствием данных по безопасности и эффективности)."},{"name":"Состав","value":"1 таблетка, покрытая пленочной оболочкой, содержит:\u003Cbr\u003Eдозировка 0,2 мг:\u003Cbr\u003Eдействующее вещество: моксонидин - 0,2 мг\u003Cbr\u003Eвспомогательные вещества (ядро): кроскармеллоза натрия (примеллоза) -19,5 мг; лактозы моногидрат (лактопресс)(сахар молочный) - 47,7 мг; целлюлоза микрокристаллическая 102-25,0 мг; повидон К30 (поливинилпирролидон среднемолекулярный) - 6,2 мг; кремния диоксид коллоидный (аэросил) - 0,4 мг; натрия стеарилфумарат - 1,0 мг;\u003Cbr\u003Eвспомогательные вещества (оболочка): гипромеллоза - 1,60 мг; полисорбат-80 (твин-80) - 0,46 мг; тальк - 0,45 мг; титана диоксид Е171 - 0,488 мг; алюминиевый лак на основе красителя кармуазин - 0,002 мг.\u003Cbr\u003Eдозировка 0,3 мг:\u003Cbr\u003Eдействующее вещество: моксонидин - 0,3 мг\u003Cbr\u003Eвспомогательные вещества (ядро): кроскармеллоза натрия (примеллоза) - 19,5 мг; лактозы моногидрат (лактопресс) (сахар молочный) - 47,6 мг; целлюлоза микрокристаллическая 102 - 25,0 мг; повидон К30 (поливинилпирролидон среднемолекулярный) - 6,2 мг; кремния диоксид коллоидный (аэросил) - 0,4 мг; натрия стеарилфумарат - 1,0 мг;\u003Cbr\u003Eвспомогательные вещества (оболочка): гипромеллоза - 1,60 мг; полисорбат-80 (твин-80) - 0,64 мг; тальк - 0,45 мг; титана диоксид Е171 - 0,30 мг; алюминиевый лак на основе красителя кармуазин - 0,01 мг.\u003Cbr\u003Eдозировка 0,4 мг:\u003Cbr\u003Eдействующее вещество: моксонидин - 0,4 мг\u003Cbr\u003Eвспомогательные вещества (ядро): кроскармеллоза натрия (примеллоза) - 19,5 мг; лактозы моногидрат (лактопресс) (сахар молочный) - 47,5 мг; целлюлоза микрокристаллическая 102 - 25,0 мг; повидон К30 (поливинилпирролидон среднемолекулярный) - 6,2 мг; кремния диоксид коллоидный (аэросил) - 0,4 мг; натрия стеарилфумарат - 1,0 мг;\u003Cbr\u003Eвспомогательные вещества (оболочка): гипромеллоза - 1,60 мг; полисорбат-80 (твин-80) - 0,64 мг; тальк - 0,45 мг; титана диоксид Е171 - 0,29 мг; алюминиевый лак на основе красителя кармуазин - 0,02 мг."},{"name":"Действующее вещество","value":"Моксонидин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28709517"]}}},{"name":"Способ применения и дозы","value":"Внутрь, независимо от приема пищи.\u003Cbr\u003EВ большинстве случаев начальная доза препарата Моксонидин-СЗ составляет 0,2 мг в сутки. Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии.\u003Cbr\u003EКоррекция дозы для пациентов с печеночной недостаточностью не требуется. Начальная доза для пациентов с умеренной или тяжелой почечной недостаточностью составляет 0,2 мг/сутки.\u003Cbr\u003EВ случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг.\u003Cbr\u003EПациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин)."},{"name":"Побочные действия","value":"Наиболее частые побочные эффекты у пациентов, принимающих моксонидин: сухость во рту, головокружение, астения и сонливость. Эти симптомы часто уменьшаются по прошествии первых недель терапии.\u003Cbr\u003EУ пациентов, принимавших участие в плацебо-контролируемых клинических исследованиях моксонидина, отмечены следующие побочные эффекты.\u003Cbr\u003EЧастота побочных эффектов, приведенных ниже, определялась соответственно следующему: очень часто (\u003E1/10); часто (\u003E1/100, \u003C1/10); нечасто (\u003E1/1000, \u003C1/100); включая отдельные сообщения. \u003Cbr\u003EСо стороны центральной нервной системы:\u003Cbr\u003EЧасто: головная боль*, головокружение (вертиго), сонливость. \u003Cbr\u003EНечасто: обморок*.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: \u003Cbr\u003EНечасто: выраженное снижение АД, ортостатическая гипотензия*, брадикардия. \u003Cbr\u003EСо стороны желудочно-кишечного тракта: \u003Cbr\u003EОчень часто: сухость слизистой оболочки полости рта. \u003Cbr\u003EЧасто: диарея, тошнота, рвота, диспепсия. \u003Cbr\u003EСо стороны кожи и подкожных тканей: \u003Cbr\u003EЧасто: кожная сыпь, зуд. \u003Cbr\u003EНечасто: ангионевротический отек. \u003Cbr\u003EНарушения психики: \u003Cbr\u003EЧасто: бессонница. \u003Cbr\u003EНечасто: нервозность. \u003Cbr\u003EСо стороны органа слуха и лабиринтные нарушения: \u003Cbr\u003EНечасто: звон в ушах. \u003Cbr\u003EСо стороны скелетно-мышечной и соединительной ткани: \u003Cbr\u003EЧасто: боль в спине. \u003Cbr\u003EНечасто: боль в области шеи. \u003Cbr\u003EОбщие расстройства и нарушения в месте введения: \u003Cbr\u003EЧасто: астения. \u003Cbr\u003EНечасто: периферические отеки. \u003Cbr\u003E(* - частота сопоставима с плацебо)."},{"name":"Фармакологическое действие","value":"Моксонидин является гипотензивным средством с центральным механизмом действия. В стволовых структурах мозга (ростральный слой боковых желудочков) моксонидин селективно стимулирует имидазолин-чувствительные рецепторы, принимающие участие в тонической и рефлекторной регуляции симпатической нервной системы. Стимуляция имидазолиновых рецепторов снижает периферическую симпатическую активность и артериальное давление (АД).\u003Cbr\u003EМоксонидин отличается от других симпатолитических гипотензивных средств более низким сродством к α2-адренорецепторам, что объясняет меньшую вероятность развития седативного эффекта и сухости во рту.\u003Cbr\u003EПрием моксонидина приводит к снижению системного сосудистого сопротивления и АД.\u003Cbr\u003EМоксонидин улучшает на 21% индекс чувствительности к инсулину (в сравнении с плацебо) у пациентов с ожирением, инсулинрезистентностью и умеренной степенью артериальной гипертензии."},{"name":"Фармакологическая группа","value":"гипотензивное средство центрального действия"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Имеются сообщения о нескольких случаях передозировки без летального исхода, когда одномоментно применялись дозы до 19,6 мг. \u003Cbr\u003EСимптомы: головная боль, седативный эффект, выраженное снижение АД, головокружение, астения, брадикардия, сухость слизистой оболочки полости рта, рвота, повышенная утомляемость, боль в эпигастральной области, угнетение дыхания и нарушение сознания. Кроме того, возможны также кратковременное повышение АД, тахикардия и гипергликемия, как было показано в нескольких исследованиях по изучению высоких доз на животных. \u003Cbr\u003EЛечение\u003Cbr\u003EСпецифического антидота не существует. В случае выраженного снижения АД может потребоваться восстановление объема циркулирующей крови за счет введения жидкости и допамина (инъекционно). \u003Cbr\u003EБрадикардия может быть купирована атропином (инъекционное введение). \u003Cbr\u003EВ тяжелых случаях передозировки рекомендуется тщательно контролировать нарушения сознания и не допускать угнетения дыхания. \u003Cbr\u003EАнтагонисты альфа-адренорецепторов могут уменьшать или устранять парадоксальные гипертензивные эффекты при передозировке моксонидином. \u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Клинические данные о применении Моксонидина-СЗ у беременных отсутствуют. В ходе исследований на животных было установлено эмбриотоксическое действие препарата.\u003Cbr\u003EМоксонидин-СЗ следует назначать беременным, только после тщательной оценки соотношения риска и пользы, когда польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод лактации\u003Cbr\u003EМоксонидин-СЗ проникает в грудное молоко и поэтому не должен назначаться во время кормления грудью. \u003Cbr\u003EМоксонидин-СПри необходимости применения Моксонидина-СЗ в период лактации, грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследования влияния препарата на способность управлять автомобилем и другими механизмами не проводились. Имеются сообщения о сонливости и головокружении в период лечения моксонидином. Это следует учитывать при выполнении вышеуказанных действий."},{"name":"Особые указания","value":"Во время лечения необходим регулярный контроль АД.\u003Cbr\u003E\n\u003Cbr\u003E\nВ постмаркетинговом наблюдении зафиксированы случаи атриовентрикулярной блокады различной степени тяжести у пациентов, принимающих моксонидин. Связь между приемом препарата Моксонидин-СЗ и замедлением атриовентрикулярной проводимости не может быть полностью исключена. Таким образом, при лечении пациентов с вероятной предрасположенностью к развитию атриовентрикулярной блокады рекомендуется соблюдать осторожность.\u003Cbr\u003E\n\u003Cbr\u003E\nПри необходимости отмены одновременного принимаемых бета-адреноблокаторов и препарата Моксонидин-СЗ сначала отменяют бета-адреноблокаторы и лишь через несколько дней Моксонидин-СЗ.\u003Cbr\u003E\n\u003Cbr\u003E\nВ настоящее время нет подтверждений того, что прекращение приема препарата Моксонидин-СЗ приводит к повышению АД.\u003Cbr\u003E\n\u003Cbr\u003E\nОднако не рекомендуется прекращать прием препарата Моксонидин-СЗ резко, вместо этого следует постепенно уменьшать дозу препарата в течении двух недель.\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов пожилого возраста может быть повышен риск развития сердечно-сосудистых осложнений вследствие применения гипотензивных препаратов, поэтому терапию препаратом Моксонидин-СЗ следует начинать с минимальной дозы."},{"name":"Взаимодействие","value":"Совместное применение моксонидина с другими гипотензивными средствами приводит к аддитивному эффекту.\u003Cbr\u003EТрициклические антидепрессанты могут снижать эффективность гипотензивных средств центрального действия, в связи с чем не рекомендуется их прием совместно с моксонидином.\u003Cbr\u003EМоксонидин может усиливать действие трициклических антидепрессантов, транквилизаторов, этанола, седативных и снотворных средств. .\u003Cbr\u003EМоксонидин способен умеренно улучшать ослабленные когнитивные функции у пациентов, получающих лоразепам.\u003Cbr\u003EМоксонидин может усиливать седативный эффект производных бензодиазепина при их одновременном назначении.\u003Cbr\u003EМоксонидин выделяется путем канальцевой секреции. Поэтому не исключено его взаимодействие с другими препаратами, выделяющимися путем канальцевой секреции."},{"name":"Регистрационный номер","value":"ЛП-002321"},{"name":"Дата государственной регистрации","value":"11.01.2023"},{"name":"Владелец регистрационного удостоверения","value":"Северная Звезда","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:16002862"]}}},{"name":"Изготовитель","value":"Северная Звезда"},{"name":"Фасовщик","value":"Северная Звезда"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Моксонидин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:17893175"]}}},{"name":"Срок годности","value":"35 мес."}]}},"fullSpecsGrouped":{"1879841396050165718":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносная система, кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия, гипертония, нормализация артериального давления, эссенциальная гипертензия"},{"name":"Показания к применению","value":"Артериальная гипертензия."},{"name":"Противопоказания","value":"- Повышенная чувствительность к активному веществу и другим компонентам препарата;\u003Cbr\u003E- синдром слабости синусового узла; ;\u003Cbr\u003E- выраженная брадикардия (частота сердечных сокращений покоя менее 50 уд/мин); ;\u003Cbr\u003E- атриовентрикулярная блокада II и III степени; ;\u003Cbr\u003E- выраженные нарушения ритма сердца; ;\u003Cbr\u003E- острая и хроническая сердечная недостаточность (III-IV функциональный класс по классификации NYHA); ;\u003Cbr\u003E- одновременное применение с трициклическими антидепрессантами (см. раздел \"Взаимодействие с другими лекарственными препаратами\");;\u003Cbr\u003E- тяжелая почечная недостаточность (КК менее 30 мл/мин); ;\u003Cbr\u003E- гемодиализ; ;\u003Cbr\u003E- период лактации; ;\u003Cbr\u003E- наследственная непереносимость лактозы, дефицит лактазы или мальабсорбция глюкозы-галактозы; ;\u003Cbr\u003E- возраст старше 75 лет; ;\u003Cbr\u003E- возраст до 18 лет (в связи с отсутствием данных по безопасности и эффективности)."},{"name":"Состав","value":"1 таблетка, покрытая пленочной оболочкой, содержит:\u003Cbr\u003Eдозировка 0,2 мг:\u003Cbr\u003Eдействующее вещество: моксонидин - 0,2 мг\u003Cbr\u003Eвспомогательные вещества (ядро): кроскармеллоза натрия (примеллоза) -19,5 мг; лактозы моногидрат (лактопресс)(сахар молочный) - 47,7 мг; целлюлоза микрокристаллическая 102-25,0 мг; повидон К30 (поливинилпирролидон среднемолекулярный) - 6,2 мг; кремния диоксид коллоидный (аэросил) - 0,4 мг; натрия стеарилфумарат - 1,0 мг;\u003Cbr\u003Eвспомогательные вещества (оболочка): гипромеллоза - 1,60 мг; полисорбат-80 (твин-80) - 0,46 мг; тальк - 0,45 мг; титана диоксид Е171 - 0,488 мг; алюминиевый лак на основе красителя кармуазин - 0,002 мг.\u003Cbr\u003Eдозировка 0,3 мг:\u003Cbr\u003Eдействующее вещество: моксонидин - 0,3 мг\u003Cbr\u003Eвспомогательные вещества (ядро): кроскармеллоза натрия (примеллоза) - 19,5 мг; лактозы моногидрат (лактопресс) (сахар молочный) - 47,6 мг; целлюлоза микрокристаллическая 102 - 25,0 мг; повидон К30 (поливинилпирролидон среднемолекулярный) - 6,2 мг; кремния диоксид коллоидный (аэросил) - 0,4 мг; натрия стеарилфумарат - 1,0 мг;\u003Cbr\u003Eвспомогательные вещества (оболочка): гипромеллоза - 1,60 мг; полисорбат-80 (твин-80) - 0,64 мг; тальк - 0,45 мг; титана диоксид Е171 - 0,30 мг; алюминиевый лак на основе красителя кармуазин - 0,01 мг.\u003Cbr\u003Eдозировка 0,4 мг:\u003Cbr\u003Eдействующее вещество: моксонидин - 0,4 мг\u003Cbr\u003Eвспомогательные вещества (ядро): кроскармеллоза натрия (примеллоза) - 19,5 мг; лактозы моногидрат (лактопресс) (сахар молочный) - 47,5 мг; целлюлоза микрокристаллическая 102 - 25,0 мг; повидон К30 (поливинилпирролидон среднемолекулярный) - 6,2 мг; кремния диоксид коллоидный (аэросил) - 0,4 мг; натрия стеарилфумарат - 1,0 мг;\u003Cbr\u003Eвспомогательные вещества (оболочка): гипромеллоза - 1,60 мг; полисорбат-80 (твин-80) - 0,64 мг; тальк - 0,45 мг; титана диоксид Е171 - 0,29 мг; алюминиевый лак на основе красителя кармуазин - 0,02 мг."},{"name":"Действующее вещество","value":"Моксонидин"},{"name":"Способ применения и дозы","value":"Внутрь, независимо от приема пищи.\u003Cbr\u003EВ большинстве случаев начальная доза препарата Моксонидин-СЗ составляет 0,2 мг в сутки. Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии.\u003Cbr\u003EКоррекция дозы для пациентов с печеночной недостаточностью не требуется. Начальная доза для пациентов с умеренной или тяжелой почечной недостаточностью составляет 0,2 мг/сутки.\u003Cbr\u003EВ случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг.\u003Cbr\u003EПациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин)."},{"name":"Побочные действия","value":"Наиболее частые побочные эффекты у пациентов, принимающих моксонидин: сухость во рту, головокружение, астения и сонливость. Эти симптомы часто уменьшаются по прошествии первых недель терапии.\u003Cbr\u003EУ пациентов, принимавших участие в плацебо-контролируемых клинических исследованиях моксонидина, отмечены следующие побочные эффекты.\u003Cbr\u003EЧастота побочных эффектов, приведенных ниже, определялась соответственно следующему: очень часто (\u003E1/10); часто (\u003E1/100, \u003C1/10); нечасто (\u003E1/1000, \u003C1/100); включая отдельные сообщения. \u003Cbr\u003EСо стороны центральной нервной системы:\u003Cbr\u003EЧасто: головная боль*, головокружение (вертиго), сонливость. \u003Cbr\u003EНечасто: обморок*.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: \u003Cbr\u003EНечасто: выраженное снижение АД, ортостатическая гипотензия*, брадикардия. \u003Cbr\u003EСо стороны желудочно-кишечного тракта: \u003Cbr\u003EОчень часто: сухость слизистой оболочки полости рта. \u003Cbr\u003EЧасто: диарея, тошнота, рвота, диспепсия. \u003Cbr\u003EСо стороны кожи и подкожных тканей: \u003Cbr\u003EЧасто: кожная сыпь, зуд. \u003Cbr\u003EНечасто: ангионевротический отек. \u003Cbr\u003EНарушения психики: \u003Cbr\u003EЧасто: бессонница. \u003Cbr\u003EНечасто: нервозность. \u003Cbr\u003EСо стороны органа слуха и лабиринтные нарушения: \u003Cbr\u003EНечасто: звон в ушах. \u003Cbr\u003EСо стороны скелетно-мышечной и соединительной ткани: \u003Cbr\u003EЧасто: боль в спине. \u003Cbr\u003EНечасто: боль в области шеи. \u003Cbr\u003EОбщие расстройства и нарушения в месте введения: \u003Cbr\u003EЧасто: астения. \u003Cbr\u003EНечасто: периферические отеки. \u003Cbr\u003E(* - частота сопоставима с плацебо)."},{"name":"Фармакологическое действие","value":"Моксонидин является гипотензивным средством с центральным механизмом действия. В стволовых структурах мозга (ростральный слой боковых желудочков) моксонидин селективно стимулирует имидазолин-чувствительные рецепторы, принимающие участие в тонической и рефлекторной регуляции симпатической нервной системы. Стимуляция имидазолиновых рецепторов снижает периферическую симпатическую активность и артериальное давление (АД).\u003Cbr\u003EМоксонидин отличается от других симпатолитических гипотензивных средств более низким сродством к α2-адренорецепторам, что объясняет меньшую вероятность развития седативного эффекта и сухости во рту.\u003Cbr\u003EПрием моксонидина приводит к снижению системного сосудистого сопротивления и АД.\u003Cbr\u003EМоксонидин улучшает на 21% индекс чувствительности к инсулину (в сравнении с плацебо) у пациентов с ожирением, инсулинрезистентностью и умеренной степенью артериальной гипертензии."},{"name":"Фармакологическая группа","value":"гипотензивное средство центрального действия"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Имеются сообщения о нескольких случаях передозировки без летального исхода, когда одномоментно применялись дозы до 19,6 мг. \u003Cbr\u003EСимптомы: головная боль, седативный эффект, выраженное снижение АД, головокружение, астения, брадикардия, сухость слизистой оболочки полости рта, рвота, повышенная утомляемость, боль в эпигастральной области, угнетение дыхания и нарушение сознания. Кроме того, возможны также кратковременное повышение АД, тахикардия и гипергликемия, как было показано в нескольких исследованиях по изучению высоких доз на животных. \u003Cbr\u003EЛечение\u003Cbr\u003EСпецифического антидота не существует. В случае выраженного снижения АД может потребоваться восстановление объема циркулирующей крови за счет введения жидкости и допамина (инъекционно). \u003Cbr\u003EБрадикардия может быть купирована атропином (инъекционное введение). \u003Cbr\u003EВ тяжелых случаях передозировки рекомендуется тщательно контролировать нарушения сознания и не допускать угнетения дыхания. \u003Cbr\u003EАнтагонисты альфа-адренорецепторов могут уменьшать или устранять парадоксальные гипертензивные эффекты при передозировке моксонидином. \u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Клинические данные о применении Моксонидина-СЗ у беременных отсутствуют. В ходе исследований на животных было установлено эмбриотоксическое действие препарата.\u003Cbr\u003EМоксонидин-СЗ следует назначать беременным, только после тщательной оценки соотношения риска и пользы, когда польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод лактации\u003Cbr\u003EМоксонидин-СЗ проникает в грудное молоко и поэтому не должен назначаться во время кормления грудью. \u003Cbr\u003EМоксонидин-СПри необходимости применения Моксонидина-СЗ в период лактации, грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследования влияния препарата на способность управлять автомобилем и другими механизмами не проводились. Имеются сообщения о сонливости и головокружении в период лечения моксонидином. Это следует учитывать при выполнении вышеуказанных действий."},{"name":"Особые указания","value":"Во время лечения необходим регулярный контроль АД.\u003Cbr\u003E\n\u003Cbr\u003E\nВ постмаркетинговом наблюдении зафиксированы случаи атриовентрикулярной блокады различной степени тяжести у пациентов, принимающих моксонидин. Связь между приемом препарата Моксонидин-СЗ и замедлением атриовентрикулярной проводимости не может быть полностью исключена. Таким образом, при лечении пациентов с вероятной предрасположенностью к развитию атриовентрикулярной блокады рекомендуется соблюдать осторожность.\u003Cbr\u003E\n\u003Cbr\u003E\nПри необходимости отмены одновременного принимаемых бета-адреноблокаторов и препарата Моксонидин-СЗ сначала отменяют бета-адреноблокаторы и лишь через несколько дней Моксонидин-СЗ.\u003Cbr\u003E\n\u003Cbr\u003E\nВ настоящее время нет подтверждений того, что прекращение приема препарата Моксонидин-СЗ приводит к повышению АД.\u003Cbr\u003E\n\u003Cbr\u003E\nОднако не рекомендуется прекращать прием препарата Моксонидин-СЗ резко, вместо этого следует постепенно уменьшать дозу препарата в течении двух недель.\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов пожилого возраста может быть повышен риск развития сердечно-сосудистых осложнений вследствие применения гипотензивных препаратов, поэтому терапию препаратом Моксонидин-СЗ следует начинать с минимальной дозы."},{"name":"Взаимодействие","value":"Совместное применение моксонидина с другими гипотензивными средствами приводит к аддитивному эффекту.\u003Cbr\u003EТрициклические антидепрессанты могут снижать эффективность гипотензивных средств центрального действия, в связи с чем не рекомендуется их прием совместно с моксонидином.\u003Cbr\u003EМоксонидин может усиливать действие трициклических антидепрессантов, транквилизаторов, этанола, седативных и снотворных средств. .\u003Cbr\u003EМоксонидин способен умеренно улучшать ослабленные когнитивные функции у пациентов, получающих лоразепам.\u003Cbr\u003EМоксонидин может усиливать седативный эффект производных бензодиазепина при их одновременном назначении.\u003Cbr\u003EМоксонидин выделяется путем канальцевой секреции. Поэтому не исключено его взаимодействие с другими препаратами, выделяющимися путем канальцевой секреции."},{"name":"Регистрационный номер","value":"ЛП-002321"},{"name":"Дата государственной регистрации","value":"11.01.2023"},{"name":"Владелец регистрационного удостоверения","value":"Северная Звезда"},{"name":"Изготовитель","value":"Северная Звезда"},{"name":"Фасовщик","value":"Северная Звезда"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Моксонидин"},{"name":"Срок годности","value":"35 мес."}]}],"transitionId":"tr_11917848027654489997"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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296 ₽

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ЕАПТЕКА
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    на основе 23 оценки
    Цена 136 ₽
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  • Моксонидин таб. п/о плен., 0.2 мг, 14 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rfa6s2dyvo/toggleWishlist":{"skuId":"228052574","productId":1401075651,"offerId":"Bfs2xETKc8qIaMQWqYOUeA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQweDw/ZjImp0hEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIw++KnAUQ3pzfbBiEqbIIINfcwQc=","sign":"aDTiv73r0MKn2G4/IaZZ8MbGV8Gnt8iqpyWkECxClV8="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rfa6s2dyvo/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин таб. п/о плен., 0.2 мг, 14 шт.

    Рейтинг товара: 5 из 5
    на основе 30 оценок
    Цена 148 ₽
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  • Моксонидин Реневал таб. п/о плен., 0.2 мг, 90 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ii0zz04fpf/toggleWishlist":{"skuId":"101770901161","productId":1754820958,"offerId":"d6KCtYQlLJoMIYG_0bgXFQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQweDw/ZjImp0hEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI3uLhxAYQqe2SkPsCGPKsgggg19zBBw==","sign":"Y+2OGs2xtyiJdkpPl4hNO5I3fgn4WfaBt3O5xfhs5Tg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ii0zz04fpf/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин Реневал таб. п/о плен., 0.2 мг, 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 21 оценка
    Цена 378 ₽
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  • Лориста таб. п/о плен., 100 мг, 30 шт.
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    Лориста таб. п/о плен., 100 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 34 оценки
    Цена 201 ₽
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  • Моксонидин-Акрихин таб. п/о плен., 0.2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-pwetp2bnhcp/toggleWishlist":{"skuId":"834997635","productId":1401075967,"offerId":"YCynmt7uRtWY2jjYa8AlDg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQweDw/ZjImp0hEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI//GKnAUQg5uUjgMYntShBSDX3MEH","sign":"uDZo8s5KqNWFMyRQ6ovj01YY56dn5060C1TcARW0vts="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-pwetp2bnhcp/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин-Акрихин таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 6 оценок
    Цена 249 ₽
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  • Моксонидин-АЛСИ таб. п/о плен., 0.2 мг, 30 шт.
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    Моксонидин-АЛСИ таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 8 оценок
    Цена 183 ₽
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  • Моксонитекс таб. п/о плен., 0.2 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vimxxjwzoll/toggleWishlist":{"skuId":"186614396","productId":1401075428,"offerId":"oUeltiHQQGQrgEhmC4l6JA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQweDw/ZjImp0hEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI5O2KnAUQ/IT+WBjEnNAHINfcwQc=","sign":"5PqKxdZDlPScI9gOuFEEcD7pYIxnfwft6VD0HLaBphs="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vimxxjwzoll/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонитекс таб. п/о плен., 0.2 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 319 ₽
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  • Моксонидин Авексима таб. п/о плен., 0.2 мг, 30 шт.
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    Моксонидин Авексима таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 7 оценок
    Цена 281 ₽
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  • Физиотенз таб. п/о плен., 0.2 мг, 28 шт.
    –15 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8wyjfreovh/toggleWishlist":{"skuId":"101393059844","productId":1401849413,"offerId":"N7Kuhh-ZbwkeTCUMtcXLlQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQweDw/ZjImp0hEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIxYy6nAUQhKD92/kCGNDE3gcg19zBBw==","sign":"hdubUq2zBJq9J2oeXOCPAPz9xhZ0MPJxv+R4BWilLVI="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8wyjfreovh/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Физиотенз таб. п/о плен., 0.2 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 6 оценок
    Цена 671 ₽ вместо 785
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  • Амлодипин таб., 5 мг, 30 шт.
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    Амлодипин таб., 5 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 36 оценок
    Цена 63 ₽
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Инструкция

Показания к применению

Артериальная гипертензия.

Противопоказания

- Повышенная чувствительность к активному веществу и другим компонентам препарата;
- синдром слабости синусового узла; ;
- выраженная брадикардия (частота сердечных сокращений покоя менее 50 уд/мин); ;
- атриовентрикулярная блокада II и III степени; ;
- выраженные нарушения ритма сердца; ;
- острая и хроническая сердечная недостаточность (III-IV функциональный класс по классификации NYHA); ;
- одновременное применение с трициклическими антидепрессантами (см. раздел "Взаимодействие с другими лекарственными препаратами");;
- тяжелая почечная недостаточность (КК менее 30 мл/мин); ;
- гемодиализ; ;
- период лактации; ;
- наследственная непереносимость лактозы, дефицит лактазы или мальабсорбция глюкозы-галактозы; ;
- возраст старше 75 лет; ;
- возраст до 18 лет (в связи с отсутствием данных по безопасности и эффективности).

Способ применения и дозы

Внутрь, независимо от приема пищи.
В большинстве случаев начальная доза препарата Моксонидин-СЗ составляет 0,2 мг в сутки. Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии.
Коррекция дозы для пациентов с печеночной недостаточностью не требуется. Начальная доза для пациентов с умеренной или тяжелой почечной недостаточностью составляет 0,2 мг/сутки.
В случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг.
Пациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин).
Полная инструкция
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Моксонидин-СЗ таб. п/о плен.
Моксонидин-СЗ таб. п/о плен., 0.2 мг, 60 шт.
4.7
(18)
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10 вопросов
Инструкция

296 ₽

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4.7
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У продавца:18 оценок·5 отзывов
У всех продавцов:279 оценок·97 отзывов
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user avatar
3 месяца назад • Наталия Сорокина • Куплен на Маркете
Достоинства: это "Скорая помощь" при повышении давления.
Недостатки: резко снимать давление не рекомендуется
Комментарий: в зависимости от давления, беру дозу. В основном по половинке таблетки
user avatar
Месяц назад • НИНА М. • Куплен на Маркете
Комментарий: цена, действие таблеток, все устраивает, покупала уже раньше. упаковка 60 таблеток тоже отлично.!
user avatar
4 месяца назад • Татьяна Иванова • Куплен на Маркете
Достоинства: Снижает давление
Недостатки: Не заметила
Комментарий: Лучше принимать ,по назначению врача !
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