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Описание

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Алмонт таб. жев., 5 мг, 28 шт.

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5.0
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Дозировка: 5 мг

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Количество штук в упаковке, шт.: 28

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Коротко о товаре

Артикул Маркета
3123188093
Тип препарата
Назначение
Действующее вещество
Возраст
от 2 лет
Инструкция
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бронхоспазма","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["36476390:36619004,36618607,36617780"]}}},{"name":"Показания к применению","value":"Профилактика и длительное лечение бронхиальной астмы у детей, включая:\u003Cbr\u003Eпредупреждение дневных и ночных симптомов заболевания (для детей от 2-х лет и старше);\u003Cbr\u003Eлечение бронхиальной астмы у пациентов с повышенной чувствительностью к ацетилсалициловой кислоте (для детей от 6-ти лет и старше);\u003Cbr\u003Eпредупреждение бронхоспазма, вызванного физической нагрузкой (для детей от 2-х лет и старше).\u003Cbr\u003EОблегчение симптомов сезонного и круглогодичного аллергического ринита у детей с 2-х лет."},{"name":"Противопоказания","value":"- Гиперчувствительность к активному или какому-либо вспомогательному веществу препарата;\u003Cbr\u003E- детский возраст до 2-х лет (для дозировки 4 мг) и до 6-ти лет (для дозировки 5 мг);\u003Cbr\u003E- пациенты с редкими наследственными заболеваниями: непереносимость галактозы, недостаточность лактазы или глюкозо-галактозная мальабсорбция;\u003Cbr\u003E- фенилкетонурия (содержит аспартам)."},{"name":"Состав","value":"1 таблетка жевательная 4 мг содержит:\u003Cbr\u003Eдействующее вещество: монтелукаст 4,00 мг (в виде монтелукаста натрия 4,16 мг);\u003Cbr\u003Eвспомогательные вещества: маннитол 160,96 мг, целлюлоза микрокристаллическая 52,80 мг, гипролоза 7.20 мг, кроскармеллоза натрия 7,20 мг, краситель Pigment Blend РВ-24880 (лактозы моногидрат 3,60 мг, краситель железа оксид красный 0,40 мг) 4,00 мг, магния стеарат 2,40 мг, аспартам 1,20 мг, ароматизатор вишневый (Silarom Cherry Flavour 1219813182) 0,08 мг.\u003Cbr\u003E1 таблетка жевательная 5 мг содержит:\u003Cbr\u003Eдействующее вещество: монтелукаст 5,00 мг (в виде монтелукаста натрия 5,20 мг);\u003Cbr\u003Eвспомогательные вещества: маннитол201,20 мг, целлюлоза микрокристаллическая 66,00 мг, гипролоза 9,00 мг, кроскармеллоза натрия 9,00 мг, краситель Pigment Blend РВ-24880 (лактозы моногидрат 4,50 мг, краситель железа оксид красный 0,50 мг) 5,00 мг, магния стеарат 3,00 мг, аспартам 1,50 мг, ароматизатор вишневый (Silarom Cherry Flavour 1219803182) 0,10 мг."},{"name":"Действующее вещество","value":"Монтелукаст","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["27144131:28708731"]}}},{"name":"Способ применения и дозы","value":"Внутрь, таблетку следует разжевать.\u003Cbr\u003EПрием препарата детьми осуществляется под наблюдением взрослых.\u003Cbr\u003EПрепарат Алмонт следует принимать за 1 час до или через 2 часа после еды.\u003Cbr\u003EПри бронхиальной астме или бронхиальной астме и аллергическом рините:\u003Cbr\u003EДля детей в возрасте от 2 до 6 лет - 1 жевательная таблетка в дозе 4 мг один раз в сутки вечером.\u003Cbr\u003EДля детей в возрасте от 6 до 14 лет - 1 жевательная таблетка в дозе 5 мг один раз в сутки вечером.\u003Cbr\u003EПри аллергическом рините:\u003Cbr\u003EДля детей в возрасте от 2 до 6 лет - 1 жевательная таблетка в дозе 4 мг один раз в сутки и для детей в возрасте от 6 до 14 лет - 1 жевательная таблетка в дозе 5 мг один раз в сутки в индивидуальном режиме в зависимости от времени наибольшего обострения симптомов.\u003Cbr\u003EНе требуется коррекции дозы внутри данных возрастных групп.\u003Cbr\u003EОбщие рекомендации\u003Cbr\u003EТерапевтический эффект препарата Алмонт, позволяющий контролировать симптомы астмы, достигается в течение суток после приема. Пациенту рекомендуется продолжать прием препарата как в периоды контролируемого течения бронхиальной астмы, так и в период обострения бронхиальной астмы.\u003Cbr\u003EПациентам с почечной недостаточностью и пациентам с печеночной недостаточностью легкой и средней степени тяжести специального подбора дозы не требуется. Не требуется коррекции дозы в зависимости от пола пациента.\u003Cbr\u003EНет данных о применении монтелукаста у пациентов с тяжелыми нарушениями функции печени.\u003Cbr\u003EДля лечения пациентов других возрастных групп доступна иная лекарственная форма и доза препарата - таблетки, покрытые пленочной оболочкой, 10 мг."},{"name":"Побочные действия","value":"Инфекционные и паразитарные заболевания: инфекции верхних дыхательных путей.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: повышение склонности к кровотечениям, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: реакции гиперчувствительности, в том числе анафилаксия, эозинофильная инфильтрация печени.\u003Cbr\u003EНарушения психики: патологические сновидения, включая ночные кошмары; галлюцинации, бессонница, сомнамбулизм, раздражительность, тревога, беспокойство; ажитация, включая агрессивное поведение или враждебность; тремор, депрессия, дезориентация, суицидальные мысли и поведение (суицидальность).\u003Cbr\u003EНарушения со стороны нервной системы: головная боль, головокружение, сонливость, парестезия/гипестезии, судороги.\u003Cbr\u003EНарушения со стороны сердца: ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: носовое кровотечение.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: диарея, сухость во рту, диспепсия, тошнота, рвота, боль в животе, панкреатит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: увеличение активности аланинаминотрансферазы и аспартатаминотрансферазы, гепатит (включая холестатические, гепатоцеллюлярные и смешанные поражения печени).\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: ангионевротический отек, склонность к появлению гематом, крапивница, кожный зуд, сыпь, узловатая эритема, многоформная эритема.\u003Cbr\u003EНарушения со стороны костно-мышечной и соединительной ткани: артралгия, миалгия, включая мышечные судороги.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: астения/усталость, недомогание, отеки, пирексия, жажда.\u003Cbr\u003EВ очень редких случаях во время лечения монтелукастом сообщалось о развитии синдрома Чардж-Стросса (смотри раздел \"Особые указания\")."},{"name":"Фармакологическое действие","value":"Цистеинил-лейкотриены (LTC4, LTD4, LTE4) - сильные провоспалительные эйкозаноиды, которые высвобождаются из разных клеток, включая тучные клетки и эозинофилы. Эти важные проастматические медиаторы связываются с цистеинил-лейкотриеновыми рецепторами (CysLT), присутствующими в дыхательных путях человека и отвечающими за реакцию бронхоспазма, выделение мокроты, проницаемость сосудов и увеличение количества эозинофилов.\u003Cbr\u003EМонтелукаст - активное при пероральном приёме соединение, которое обладает большим сродством и селективностью к CysLT1-рецепторам. Монтелукаст в дозе менее 5 мг купирует бронхоспазм, индуцированный ингаляцией LTD4. Бронходилатирующий эффект наблюдается в течение 2 часов после перорального применения. Бронходилатирующий эффект бета2-адреномиметиков усиливается при приеме монтелукаста. Монтелукаст подавляет как раннюю, так и позднюю стадии бронхоспазма, вызванного воздействием антигенов. Монтелукаст снижает число эозинофилов в периферической крови у взрослых и детей, а также значительно снижает число эозинофилов в дыхательных путях. У пациентов с повышенной чувствительностью к ацетилсалициловой кислоте, получающих ингаляционные и/или пероральные глюкокортикостериоды (ГКС), добавление к терапии монтелукаста обеспечивает лучший контроль заболевания."},{"name":"Фармакологическая группа","value":"противовоспалительное антибронхоконстрикторное средство - лейкотриеновых рецепторов блокатор"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 2 лет"},{"name":"Условия хранения","value":"При температуре не выше 30 °С, в оригинальной упаковке."},{"name":"Передозировка","value":"Симптомы передозировки препарата у пациентов с хронической бронхиальной астмой при применении в дозе, превышающей 200 мг в сутки, в течение 22 недель и в дозе 900 мг в сутки - в течение 1 недели, не выявлены.\u003Cbr\u003EИмеются сообщения об острой передозировке монтелукаста (при приеме не менее 1 г в сутки) в постмаркетинговом периоде и в клинических исследованиях у взрослых и детей. Клинические и лабораторные данные при этом свидетельствуют о соответствии профиля безопасности препарата у детей, взрослых и пациентов пожилого возраста. Наиболее частыми симптомами были чувство жажды, сонливость, рвота, психомоторное возбуждение, головная боль и боль в животе.\u003Cbr\u003EЛечение: проведение симптоматической терапии.\u003Cbr\u003EДанные о возможности выведения монтелукаста путем перитонеального диализа или гемодиализа отсутствуют."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Алмонт при беременности возможно в случае, если предполагаемая польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EРешение об отмене грудного вскармливания на период применения препарата Алмонт принимается на основании оценки о предполагаемой пользе для матери и потенциального риска для ребенка."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Как правило, монтелукаст не влияет на способность к управлению транспортными средствами или работу с другими механизмами, но очень редко у некоторых пациентов отмечали сонливость и головокружение, при появлении этих признаков пациентам не рекомендуется управлять транспортными средствами и заниматься другими видами деятельности, требующими концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Препарат Алмонт не рекомендуется назначать для лечения острых приступов бронхиальной астмы. Пациентам с бронхиальной астмой рекомендуется всегда иметь при себе препараты экстренной помощи. При наступлении острого приступа следует применять ингаляционные бета2-адреномиметики короткого действия. Пациенты должны как можно быстрее проконсультироваться со своим врачом, если им необходимо большее количество ингаляций бета2-адреномиметиков короткого действия, чем обычно.\u003Cbr\u003EНе следует резко заменять препарат Алмонт терапией ингаляционными или пероральными ГКС. Отсутствуют данные, доказывающие возможность снижения дозы пероральных ГКС на фоне одновременного приёма монтелукаста.\u003Cbr\u003EВ редких случаях у пациентов, которые получают антиастматические препараты, включая монтелукаст, может развиться системная эозинофилия, что иногда сопровождается клиническими признаками васкулита, так называемый синдром Чардж-Стросса, состояние, которое устраняют с помощью приема системных ГКС. Эти случаи, как правило, ассоциируются с уменьшением дозы или отменой терапии пероральными ГКС. Нельзя исключить или установить вероятность того, что антагонисты лейкотриеновых рецепторов могут ассоциироваться с развитием синдрома Чардж-Стросса. Поэтому врачей необходимо предупредить о возможности возникновения эозинофилии, васкулярной сыпи, увеличения выраженности лёгочных симптомов, сердечных осложнений и/или нейропатии у пациентов. Пациентам, у которых развивались вышеупомянутые симптомы, необходимо пройти повторное обследование, а схему их лечения пересмотреть.\u003Cbr\u003EЛечение препаратом Алмонт не приводит к профилактике развития бронхоспазма у пациентов с повышенной чувствительностью к ацетилсалициловой кислоте при применении ацетилсалициловой кислоты и других нестероидных противовоспалительных препаратов.\u003Cbr\u003EПрепарат Алмонт содержит аспартам, источник фенилаланина. Данный препарат может причинить вред здоровью пациентам с фенилкетонурией.\u003Cbr\u003EПрепарат содержит лактозу моногидрат и его не следует принимать пациентам с редкими наследственными заболеваниями: непереносимость галактозы, недостаточность лактазы или глюкозо-галактозная мальабсорбция."},{"name":"Взаимодействие","value":"У пациентов, одновременно получавших фенобарбитал, площадь под фармакокинетической кривой \"концентрация-время\" монтелукаста уменьшалась примерно на 40%, однако коррекции режима дозирования у таких пациентов не требуется. Поскольку монтелукаст метаболизируется изоферментом CYP3A4, следует соблюдать осторожность, особенно у детей, если монтелукаст одновременно применяется с индукторами изофермента CYP3A4, такими как фенитоин, фенобарбитал и рифампицин.\u003Cbr\u003EМонтелукаст можно назначать вместе с другими лекарственными средствами, традиционно применяемыми для профилактики и длительного лечения бронхиальной астмы и/или аллергического ринита.\u003Cbr\u003EМонтелукаст в рекомендуемой терапевтической дозе не оказывал клинически значимого эффекта на фармакокинетику следующих препаратов: теофиллин, преднизон, преднизолон, пероральные контрацептивы (этинилэстрадиол/норэтинодрел 35/1), терфенадин, дигоксин и варфарин.\u003Cbr\u003EВ исследованиях in vitro установлено, что монтелукаст является сильным ингибитором изофермента CYP2C8. Однако при исследовании лекарственного взаимодействия in vivo монтелукаста и росиглитазона (маркерный субстрат, представитель препаратов, первично метаболизирующихся изоферментом CYP2C8) не получено подтверждения ингибирования монтелукастом изофермента CYP2C8. Таким образом, в клинической практике не предполагается влияние монтелукаста на СУР2С8-опосредованный метаболизм ряда лекарственных препаратов, в т.ч. паклитаксела, росиглитазона, репаглинида.\u003Cbr\u003EИсследования in vitro показали, что монтелукаст является субстратом изофермента CYP2C8, и в меньшей степени изоферментов CYP2C9 и 3А4. Данные клинического исследования лекарственного взаимодействия в отношении монтелукаста и гемфиброзила (ингибитора как CYP2C8, так и 2С9) демонстрируют, что гемфиброзил повышает эффект системного воздействия монтелукаста в 4,4 раза. Совместный приём итраконазола, сильного ингибитора изофермента CYP3A4, вместе с гемфиброзилом и монтелукастом не приводил к дополнительному повышению эффекта системного воздействия монтелукаста. Влияние гемфиброзила на системное воздействие монтелукаста не может считаться клинически значимым на основании данных по безопасности при применении в дозах, превышающих одобренную дозу 10 мг для взрослых пациентов (например, 200 мг/день для взрослых пациентов в течение 22 недель и до 900 мг/день для пациентов, принимающих препарат в течение примерно одной недели не наблюдалось клинически значимых отрицательных эффектов). Таким образом, при совместном приеме вместе с гемфиброзилом коррекции дозы монтелукаста не требуется. По результатам исследований in vitro, не предполагается клинически значимых лекарственных взаимодействий с другими известными ингибиторами изофермента CYP2C8 (например, с триметопримом). Кроме того, совместный приём монтелукаста с одним только итраконазолом не приводил к существенному повышению эффекта системного воздействия монтелукаста.\u003Cbr\u003EКомбинированное лечение с бронходилататорами\u003Cbr\u003EПрепарат Алмонт является обоснованным дополнением к монотерапии бронходилататорами, если последние не обеспечивают адекватного контроля бронхиальной астмы. По достижении терапевтического эффекта от лечения препаратом Алмонт можно начать постепенное снижение дозы бронходилататоров.\u003Cbr\u003EКомбинированное лечение с ингаляционными ГКС\u003Cbr\u003EЛечение препаратом Алмонт обеспечивает дополнительный терапевтический эффект пациентам, применяющим ингаляционные ГКС. По достижении стабилизации состояния можно начать постепенное снижение дозы ГКС под наблюдением врача. В некоторых случаях допустима полная отмена ингаляционных ГКС, однако резкая замена ингаляционных ГКС на препарат Алмонт не рекомендуется."},{"name":"Регистрационный номер","value":"ЛП-002407"},{"name":"Дата государственной регистрации","value":"22.03.2019"},{"name":"Владелец регистрационного удостоверения","value":"Actavis Group PTC","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["34324371:35649313","7893318:35854150"]}}},{"name":"Изготовитель","value":"Actavis"},{"name":"Фасовщик","value":"Actavis"},{"name":"Страна бренда","value":"Исландия"},{"name":"Страна-производитель","value":"Мальта"},{"name":"Название препарата","value":"Алмонт","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["17796364:26106492"]}}},{"name":"Срок годности","value":"35 мес."}]}},"fullSpecsGrouped":{"5299281609318198572":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"дыхательная система"},{"name":"Назначение","value":"аллергический ринит, бронхиальная астма, профилактика и лечение бронхоспазма"},{"name":"Показания к применению","value":"Профилактика и длительное лечение бронхиальной астмы у детей, включая:\u003Cbr\u003Eпредупреждение дневных и ночных симптомов заболевания (для детей от 2-х лет и старше);\u003Cbr\u003Eлечение бронхиальной астмы у пациентов с повышенной чувствительностью к ацетилсалициловой кислоте (для детей от 6-ти лет и старше);\u003Cbr\u003Eпредупреждение бронхоспазма, вызванного физической нагрузкой (для детей от 2-х лет и старше).\u003Cbr\u003EОблегчение симптомов сезонного и круглогодичного аллергического ринита у детей с 2-х лет."},{"name":"Противопоказания","value":"- Гиперчувствительность к активному или какому-либо вспомогательному веществу препарата;\u003Cbr\u003E- детский возраст до 2-х лет (для дозировки 4 мг) и до 6-ти лет (для дозировки 5 мг);\u003Cbr\u003E- пациенты с редкими наследственными заболеваниями: непереносимость галактозы, недостаточность лактазы или глюкозо-галактозная мальабсорбция;\u003Cbr\u003E- фенилкетонурия (содержит аспартам)."},{"name":"Состав","value":"1 таблетка жевательная 4 мг содержит:\u003Cbr\u003Eдействующее вещество: монтелукаст 4,00 мг (в виде монтелукаста натрия 4,16 мг);\u003Cbr\u003Eвспомогательные вещества: маннитол 160,96 мг, целлюлоза микрокристаллическая 52,80 мг, гипролоза 7.20 мг, кроскармеллоза натрия 7,20 мг, краситель Pigment Blend РВ-24880 (лактозы моногидрат 3,60 мг, краситель железа оксид красный 0,40 мг) 4,00 мг, магния стеарат 2,40 мг, аспартам 1,20 мг, ароматизатор вишневый (Silarom Cherry Flavour 1219813182) 0,08 мг.\u003Cbr\u003E1 таблетка жевательная 5 мг содержит:\u003Cbr\u003Eдействующее вещество: монтелукаст 5,00 мг (в виде монтелукаста натрия 5,20 мг);\u003Cbr\u003Eвспомогательные вещества: маннитол201,20 мг, целлюлоза микрокристаллическая 66,00 мг, гипролоза 9,00 мг, кроскармеллоза натрия 9,00 мг, краситель Pigment Blend РВ-24880 (лактозы моногидрат 4,50 мг, краситель железа оксид красный 0,50 мг) 5,00 мг, магния стеарат 3,00 мг, аспартам 1,50 мг, ароматизатор вишневый (Silarom Cherry Flavour 1219803182) 0,10 мг."},{"name":"Действующее вещество","value":"Монтелукаст"},{"name":"Способ применения и дозы","value":"Внутрь, таблетку следует разжевать.\u003Cbr\u003EПрием препарата детьми осуществляется под наблюдением взрослых.\u003Cbr\u003EПрепарат Алмонт следует принимать за 1 час до или через 2 часа после еды.\u003Cbr\u003EПри бронхиальной астме или бронхиальной астме и аллергическом рините:\u003Cbr\u003EДля детей в возрасте от 2 до 6 лет - 1 жевательная таблетка в дозе 4 мг один раз в сутки вечером.\u003Cbr\u003EДля детей в возрасте от 6 до 14 лет - 1 жевательная таблетка в дозе 5 мг один раз в сутки вечером.\u003Cbr\u003EПри аллергическом рините:\u003Cbr\u003EДля детей в возрасте от 2 до 6 лет - 1 жевательная таблетка в дозе 4 мг один раз в сутки и для детей в возрасте от 6 до 14 лет - 1 жевательная таблетка в дозе 5 мг один раз в сутки в индивидуальном режиме в зависимости от времени наибольшего обострения симптомов.\u003Cbr\u003EНе требуется коррекции дозы внутри данных возрастных групп.\u003Cbr\u003EОбщие рекомендации\u003Cbr\u003EТерапевтический эффект препарата Алмонт, позволяющий контролировать симптомы астмы, достигается в течение суток после приема. Пациенту рекомендуется продолжать прием препарата как в периоды контролируемого течения бронхиальной астмы, так и в период обострения бронхиальной астмы.\u003Cbr\u003EПациентам с почечной недостаточностью и пациентам с печеночной недостаточностью легкой и средней степени тяжести специального подбора дозы не требуется. Не требуется коррекции дозы в зависимости от пола пациента.\u003Cbr\u003EНет данных о применении монтелукаста у пациентов с тяжелыми нарушениями функции печени.\u003Cbr\u003EДля лечения пациентов других возрастных групп доступна иная лекарственная форма и доза препарата - таблетки, покрытые пленочной оболочкой, 10 мг."},{"name":"Побочные действия","value":"Инфекционные и паразитарные заболевания: инфекции верхних дыхательных путей.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: повышение склонности к кровотечениям, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: реакции гиперчувствительности, в том числе анафилаксия, эозинофильная инфильтрация печени.\u003Cbr\u003EНарушения психики: патологические сновидения, включая ночные кошмары; галлюцинации, бессонница, сомнамбулизм, раздражительность, тревога, беспокойство; ажитация, включая агрессивное поведение или враждебность; тремор, депрессия, дезориентация, суицидальные мысли и поведение (суицидальность).\u003Cbr\u003EНарушения со стороны нервной системы: головная боль, головокружение, сонливость, парестезия/гипестезии, судороги.\u003Cbr\u003EНарушения со стороны сердца: ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: носовое кровотечение.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: диарея, сухость во рту, диспепсия, тошнота, рвота, боль в животе, панкреатит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: увеличение активности аланинаминотрансферазы и аспартатаминотрансферазы, гепатит (включая холестатические, гепатоцеллюлярные и смешанные поражения печени).\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: ангионевротический отек, склонность к появлению гематом, крапивница, кожный зуд, сыпь, узловатая эритема, многоформная эритема.\u003Cbr\u003EНарушения со стороны костно-мышечной и соединительной ткани: артралгия, миалгия, включая мышечные судороги.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: астения/усталость, недомогание, отеки, пирексия, жажда.\u003Cbr\u003EВ очень редких случаях во время лечения монтелукастом сообщалось о развитии синдрома Чардж-Стросса (смотри раздел \"Особые указания\")."},{"name":"Фармакологическое действие","value":"Цистеинил-лейкотриены (LTC4, LTD4, LTE4) - сильные провоспалительные эйкозаноиды, которые высвобождаются из разных клеток, включая тучные клетки и эозинофилы. Эти важные проастматические медиаторы связываются с цистеинил-лейкотриеновыми рецепторами (CysLT), присутствующими в дыхательных путях человека и отвечающими за реакцию бронхоспазма, выделение мокроты, проницаемость сосудов и увеличение количества эозинофилов.\u003Cbr\u003EМонтелукаст - активное при пероральном приёме соединение, которое обладает большим сродством и селективностью к CysLT1-рецепторам. Монтелукаст в дозе менее 5 мг купирует бронхоспазм, индуцированный ингаляцией LTD4. Бронходилатирующий эффект наблюдается в течение 2 часов после перорального применения. Бронходилатирующий эффект бета2-адреномиметиков усиливается при приеме монтелукаста. Монтелукаст подавляет как раннюю, так и позднюю стадии бронхоспазма, вызванного воздействием антигенов. Монтелукаст снижает число эозинофилов в периферической крови у взрослых и детей, а также значительно снижает число эозинофилов в дыхательных путях. У пациентов с повышенной чувствительностью к ацетилсалициловой кислоте, получающих ингаляционные и/или пероральные глюкокортикостериоды (ГКС), добавление к терапии монтелукаста обеспечивает лучший контроль заболевания."},{"name":"Фармакологическая группа","value":"противовоспалительное антибронхоконстрикторное средство - лейкотриеновых рецепторов блокатор"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 2 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 30 °С, в оригинальной упаковке."},{"name":"Передозировка","value":"Симптомы передозировки препарата у пациентов с хронической бронхиальной астмой при применении в дозе, превышающей 200 мг в сутки, в течение 22 недель и в дозе 900 мг в сутки - в течение 1 недели, не выявлены.\u003Cbr\u003EИмеются сообщения об острой передозировке монтелукаста (при приеме не менее 1 г в сутки) в постмаркетинговом периоде и в клинических исследованиях у взрослых и детей. Клинические и лабораторные данные при этом свидетельствуют о соответствии профиля безопасности препарата у детей, взрослых и пациентов пожилого возраста. Наиболее частыми симптомами были чувство жажды, сонливость, рвота, психомоторное возбуждение, головная боль и боль в животе.\u003Cbr\u003EЛечение: проведение симптоматической терапии.\u003Cbr\u003EДанные о возможности выведения монтелукаста путем перитонеального диализа или гемодиализа отсутствуют."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Алмонт при беременности возможно в случае, если предполагаемая польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EРешение об отмене грудного вскармливания на период применения препарата Алмонт принимается на основании оценки о предполагаемой пользе для матери и потенциального риска для ребенка."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Как правило, монтелукаст не влияет на способность к управлению транспортными средствами или работу с другими механизмами, но очень редко у некоторых пациентов отмечали сонливость и головокружение, при появлении этих признаков пациентам не рекомендуется управлять транспортными средствами и заниматься другими видами деятельности, требующими концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Препарат Алмонт не рекомендуется назначать для лечения острых приступов бронхиальной астмы. Пациентам с бронхиальной астмой рекомендуется всегда иметь при себе препараты экстренной помощи. При наступлении острого приступа следует применять ингаляционные бета2-адреномиметики короткого действия. Пациенты должны как можно быстрее проконсультироваться со своим врачом, если им необходимо большее количество ингаляций бета2-адреномиметиков короткого действия, чем обычно.\u003Cbr\u003EНе следует резко заменять препарат Алмонт терапией ингаляционными или пероральными ГКС. Отсутствуют данные, доказывающие возможность снижения дозы пероральных ГКС на фоне одновременного приёма монтелукаста.\u003Cbr\u003EВ редких случаях у пациентов, которые получают антиастматические препараты, включая монтелукаст, может развиться системная эозинофилия, что иногда сопровождается клиническими признаками васкулита, так называемый синдром Чардж-Стросса, состояние, которое устраняют с помощью приема системных ГКС. Эти случаи, как правило, ассоциируются с уменьшением дозы или отменой терапии пероральными ГКС. Нельзя исключить или установить вероятность того, что антагонисты лейкотриеновых рецепторов могут ассоциироваться с развитием синдрома Чардж-Стросса. Поэтому врачей необходимо предупредить о возможности возникновения эозинофилии, васкулярной сыпи, увеличения выраженности лёгочных симптомов, сердечных осложнений и/или нейропатии у пациентов. Пациентам, у которых развивались вышеупомянутые симптомы, необходимо пройти повторное обследование, а схему их лечения пересмотреть.\u003Cbr\u003EЛечение препаратом Алмонт не приводит к профилактике развития бронхоспазма у пациентов с повышенной чувствительностью к ацетилсалициловой кислоте при применении ацетилсалициловой кислоты и других нестероидных противовоспалительных препаратов.\u003Cbr\u003EПрепарат Алмонт содержит аспартам, источник фенилаланина. Данный препарат может причинить вред здоровью пациентам с фенилкетонурией.\u003Cbr\u003EПрепарат содержит лактозу моногидрат и его не следует принимать пациентам с редкими наследственными заболеваниями: непереносимость галактозы, недостаточность лактазы или глюкозо-галактозная мальабсорбция."},{"name":"Взаимодействие","value":"У пациентов, одновременно получавших фенобарбитал, площадь под фармакокинетической кривой \"концентрация-время\" монтелукаста уменьшалась примерно на 40%, однако коррекции режима дозирования у таких пациентов не требуется. Поскольку монтелукаст метаболизируется изоферментом CYP3A4, следует соблюдать осторожность, особенно у детей, если монтелукаст одновременно применяется с индукторами изофермента CYP3A4, такими как фенитоин, фенобарбитал и рифампицин.\u003Cbr\u003EМонтелукаст можно назначать вместе с другими лекарственными средствами, традиционно применяемыми для профилактики и длительного лечения бронхиальной астмы и/или аллергического ринита.\u003Cbr\u003EМонтелукаст в рекомендуемой терапевтической дозе не оказывал клинически значимого эффекта на фармакокинетику следующих препаратов: теофиллин, преднизон, преднизолон, пероральные контрацептивы (этинилэстрадиол/норэтинодрел 35/1), терфенадин, дигоксин и варфарин.\u003Cbr\u003EВ исследованиях in vitro установлено, что монтелукаст является сильным ингибитором изофермента CYP2C8. Однако при исследовании лекарственного взаимодействия in vivo монтелукаста и росиглитазона (маркерный субстрат, представитель препаратов, первично метаболизирующихся изоферментом CYP2C8) не получено подтверждения ингибирования монтелукастом изофермента CYP2C8. Таким образом, в клинической практике не предполагается влияние монтелукаста на СУР2С8-опосредованный метаболизм ряда лекарственных препаратов, в т.ч. паклитаксела, росиглитазона, репаглинида.\u003Cbr\u003EИсследования in vitro показали, что монтелукаст является субстратом изофермента CYP2C8, и в меньшей степени изоферментов CYP2C9 и 3А4. Данные клинического исследования лекарственного взаимодействия в отношении монтелукаста и гемфиброзила (ингибитора как CYP2C8, так и 2С9) демонстрируют, что гемфиброзил повышает эффект системного воздействия монтелукаста в 4,4 раза. Совместный приём итраконазола, сильного ингибитора изофермента CYP3A4, вместе с гемфиброзилом и монтелукастом не приводил к дополнительному повышению эффекта системного воздействия монтелукаста. Влияние гемфиброзила на системное воздействие монтелукаста не может считаться клинически значимым на основании данных по безопасности при применении в дозах, превышающих одобренную дозу 10 мг для взрослых пациентов (например, 200 мг/день для взрослых пациентов в течение 22 недель и до 900 мг/день для пациентов, принимающих препарат в течение примерно одной недели не наблюдалось клинически значимых отрицательных эффектов). Таким образом, при совместном приеме вместе с гемфиброзилом коррекции дозы монтелукаста не требуется. По результатам исследований in vitro, не предполагается клинически значимых лекарственных взаимодействий с другими известными ингибиторами изофермента CYP2C8 (например, с триметопримом). Кроме того, совместный приём монтелукаста с одним только итраконазолом не приводил к существенному повышению эффекта системного воздействия монтелукаста.\u003Cbr\u003EКомбинированное лечение с бронходилататорами\u003Cbr\u003EПрепарат Алмонт является обоснованным дополнением к монотерапии бронходилататорами, если последние не обеспечивают адекватного контроля бронхиальной астмы. По достижении терапевтического эффекта от лечения препаратом Алмонт можно начать постепенное снижение дозы бронходилататоров.\u003Cbr\u003EКомбинированное лечение с ингаляционными ГКС\u003Cbr\u003EЛечение препаратом Алмонт обеспечивает дополнительный терапевтический эффект пациентам, применяющим ингаляционные ГКС. По достижении стабилизации состояния можно начать постепенное снижение дозы ГКС под наблюдением врача. В некоторых случаях допустима полная отмена ингаляционных ГКС, однако резкая замена ингаляционных ГКС на препарат Алмонт не рекомендуется."},{"name":"Регистрационный номер","value":"ЛП-002407"},{"name":"Дата государственной регистрации","value":"22.03.2019"},{"name":"Владелец регистрационного удостоверения","value":"Actavis Group PTC"},{"name":"Изготовитель","value":"Actavis"},{"name":"Фасовщик","value":"Actavis"},{"name":"Страна бренда","value":"Исландия"},{"name":"Страна-производитель","value":"Мальта"},{"name":"Название препарата","value":"Алмонт"},{"name":"Срок годности","value":"35 мес."}]}],"transitionId":"tr_993394452479942077"}}}}
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Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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    Цена 1 349 ₽
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  • Сингуляр таб. жев., 4 мг, 14 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6c66vonxug8/toggleWishlist":{"skuId":"186487584","productId":1436721413,"offerId":"6zKHzz8a_zQUa_QBbLZEvg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrMrL2+XRiYNPEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIhcKKrQUQoKb2WBiE3LAIIOHcwQc=","sign":"jmMIniFfUk52L++UHGAJSt+VlhGuHYVCe6tUd0Ng0EE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6c66vonxug8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Сингуляр таб. жев., 4 мг, 14 шт.

    Рейтинг товара: 4.8 из 5
    на основе 19 оценок
    Цена 1 399 ₽
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  • Монтелукаст таб. п/о плен., 10 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wu0bxrqo7w/toggleWishlist":{"skuId":"661312006","productId":1436721458,"offerId":"2Hkv9GqGb-x9SZKTwt4Uvg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrMrL2+XRiYNPEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIssKKrQUQhqSruwIYn+PQByDh3MEH","sign":"yllkb8ytPdOZ+s05tcE18gLqT4DF8LeBrbcpKwfHm+A="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wu0bxrqo7w/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Монтелукаст таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 70 оценок
    Цена 641 ₽
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  • Монтелар таб. жев., 5 мг, 14 шт.
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    Монтелар таб. жев., 5 мг, 14 шт.

    Рейтинг товара: 4.9 из 5
    на основе 10 оценок
    Цена 815 ₽
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  • Монтелукаст-ВЕРТЕКС таб. п/о плен., 10 мг, 15 шт.
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    Монтелукаст-ВЕРТЕКС таб. п/о плен., 10 мг, 15 шт.

    Рейтинг товара: 4.9 из 5
    на основе 14 оценок
    Цена 329 ₽
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  • Монтелукаст таб. жев., 5 мг, 28 шт.
    –15 %
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    Монтелукаст таб. жев., 5 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 953 ₽ вместо 1 122
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  • Сингуляр таб. п/о, 10 мг, 28 шт.
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    Сингуляр таб. п/о, 10 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 1 879 ₽
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  • Синглон таб. жев., 5 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kvccglnq26a/toggleWishlist":{"skuId":"186858092","productId":1436721416,"offerId":"bwu_n3mGGXQa5dgE2FjPZw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrMrL2+XRiYNPEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIiMKKrQUQ7PSMWRj+1bYIIOHcwQc=","sign":"Lrtygb0zMnNnwpnDazdkmaT0mTJNRz5Wx/b1SiZlx04="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kvccglnq26a/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Синглон таб. жев., 5 мг, 28 шт.

    Рейтинг товара: 4.4 из 5
    на основе 29 оценок
    Цена 1 289 ₽
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  • Экталуст таб. жев., 4 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qhttsxsait/toggleWishlist":{"skuId":"101627987223","productId":1436721424,"offerId":"7seZPCggollhpfFyQp3Hug","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrMrL2+XRiYNPEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIkMKKrQUQl4qAzPoCGM7C2Qcg4dzBBw==","sign":"vwuoRr9c6RApJC22nRNQ/DQ1lmmTf5H7zyTR3N/kppo="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qhttsxsait/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Экталуст таб. жев., 4 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 19 оценок
    Цена 441 ₽
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  • МОНТЕЛУКАСТ-АЛИУМ таб. жев., 5 мг, 30 шт.
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    МОНТЕЛУКАСТ-АЛИУМ таб. жев., 5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 1 146 ₽
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  • Монтелар таб. п/о плен., 10 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-oynv0mg2p8t/toggleWishlist":{"skuId":"453474085","productId":1436721452,"offerId":"8wYvrgOo0FPpZyZPJiR0Jw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrMrL2+XRiYNPEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIrMKKrQUQpe6d2AEYxJzQByDh3MEH","sign":"NCNHw3XmjAq9Yt7rmhxC3Ghjm2pOY+M/JlgbQSJMg2s="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-oynv0mg2p8t/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Монтелар таб. п/о плен., 10 мг, 28 шт.

    Рейтинг товара: 4.8 из 5
    на основе 4 оценки
    Цена 1 099 ₽
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  • Монтелукаст-Алиум таблетки п/о плен., 10 мг, 30 шт.
    –10 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-komloui1lh9/toggleWishlist":{"skuId":"101787831167","productId":1760208256,"offerId":"0uiN9trtYSFS1QiKmzRHNA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrMrL2+XRiYNPEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIgMuqxwYQ/5acmPsCGLGLuggg4dzBBw==","sign":"XGQBlm5/7kxU8pFUfu1p46Zzsfh+pxEmQ1aOnEoWWkg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-komloui1lh9/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Монтелукаст-Алиум таблетки п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 4 оценки
    Цена 689 ₽ вместо 766
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Инструкция

Показания к применению

Профилактика и длительное лечение бронхиальной астмы у детей, включая:
предупреждение дневных и ночных симптомов заболевания (для детей от 2-х лет и старше);
лечение бронхиальной астмы у пациентов с повышенной чувствительностью к ацетилсалициловой кислоте (для детей от 6-ти лет и старше);
предупреждение бронхоспазма, вызванного физической нагрузкой (для детей от 2-х лет и старше).
Облегчение симптомов сезонного и круглогодичного аллергического ринита у детей с 2-х лет.

Противопоказания

- Гиперчувствительность к активному или какому-либо вспомогательному веществу препарата;
- детский возраст до 2-х лет (для дозировки 4 мг) и до 6-ти лет (для дозировки 5 мг);
- пациенты с редкими наследственными заболеваниями: непереносимость галактозы, недостаточность лактазы или глюкозо-галактозная мальабсорбция;
- фенилкетонурия (содержит аспартам).

Способ применения и дозы

Внутрь, таблетку следует разжевать.
Прием препарата детьми осуществляется под наблюдением взрослых.
Препарат Алмонт следует принимать за 1 час до или через 2 часа после еды.
При бронхиальной астме или бронхиальной астме и аллергическом рините:
Для детей в возрасте от 2 до 6 лет - 1 жевательная таблетка в дозе 4 мг один раз в сутки вечером.
Для детей в возрасте от 6 до 14 лет - 1 жевательная таблетка в дозе 5 мг один раз в сутки вечером.
При аллергическом рините:
Для детей в возрасте от 2 до 6 лет - 1 жевательная таблетка в дозе 4 мг один раз в сутки и для детей в возрасте от 6 до 14 лет - 1 жевательная таблетка в дозе 5 мг один раз в сутки в индивидуальном режиме в зависимости от времени наибольшего обострения симптомов.
Не требуется коррекции дозы внутри данных возрастных групп.
Общие рекомендации
Терапевтический эффект препарата Алмонт, позволяющий контролировать симптомы астмы, достигается в течение суток после приема. Пациенту рекомендуется продолжать прием препарата как в периоды контролируемого течения бронхиальной астмы, так и в период обострения бронхиальной астмы.
Пациентам с почечной недостаточностью и пациентам с печеночной недостаточностью легкой и средней степени тяжести специального подбора дозы не требуется. Не требуется коррекции дозы в зависимости от пола пациента.
Нет данных о применении монтелукаста у пациентов с тяжелыми нарушениями функции печени.
Для лечения пациентов других возрастных групп доступна иная лекарственная форма и доза препарата - таблетки, покрытые пленочной оболочкой, 10 мг.
Полная инструкция
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Алмонт таб. жев.
Алмонт таб. жев., 5 мг, 28 шт.
5.0
(1)
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1 вопрос
Инструкция

1 239 ₽

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5.0
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У продавца:1 оценка·1 отзыв
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3 месяца назад • Александр • Куплен на Маркете
Достоинства: В еаптеке хорошая цена, брала супруга для ребёнка в связи с приближающейся весной от заложености носоглотки
Комментарий: Каждую весну покупаем
Посмотреть все отзывы на Маркете
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