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Описание

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Фосфоглив капс., 50 шт.

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4.9
(113)
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Коротко о товаре

Артикул Маркета
3123137256
Тип препарата
Назначение
Действующее вещество
Возраст
от 12 лет
Инструкция
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Срок годности - 3 года.\u003Cbr\u003E"},{"name":"Передозировка","value":"В настоящее время случаи передозировки препарата Фосфоглив не зарегистрированы.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан при беременности и в период грудного вскармливания (данных по эффективности и безопасности недостаточно)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат не оказывает негативного влияния на способность управлять транспортными средствами и выполнять другую работу, требующую повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"В случае повышения артериального давления следует прекратить прием препарата и обратиться к врачу.\u003Cbr\u003EС осторожностью следует назначать препарат пациентам с портальной гипертензией, артериальной гипертензией. 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Капсулы следует проглатывать, не разжевывая, запивая небольшим количеством жидкости.\u003Cbr\u003EВзрослым и детям старше 12 лет назначают по 2 капс. 3 раза/сут.\u003Cbr\u003EДлительность применения может составлять до 6 мес, в среднем - 3 мес.\u003Cbr\u003E"},{"name":"Побочные действия","value":"Обычно препарат Фосфоглив переносится хорошо, побочные действия развиваются очень редко, по данным пострегистрационного наблюдения частота \u003C1/10 000.\u003Cbr\u003EАллергические реакции: кожная сыпь, затруднение носового дыхания, конъюнктивит, кашель.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: транзиторное (преходящее) повышение АД, периферические отеки.\u003Cbr\u003EСо стороны пищеварительной системы: диспепсия (отрыжка, тошнота, вздутие живота), дискомфорт в животе.\u003Cbr\u003EПри возникновении перечисленных симптомов следует прекратить прием препарата и проконсультироваться с врачом.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Комбинированное средство. Оказывает гепатопротекторное, мембраностабилизирующее и противовирусное действие. Глицирризиновая кислота оказывает гепатопротекторное действие за счет антиоксидантного, противовоспалительного эффектов, а также влияния на фиброгенез. Антиоксидантное действие. Глицирризиновая кислота связывает свободные кислородные радикалы и ингибирует ферменты, инициирующие перекисное окисление липидов (ПОЛ) в гепатоцитах.\u003Cbr\u003E\nПротивовоспалительное действие. Глицирризиновая кислота уменьшает воспаление за счет ингибирующего влияния на NF-kB- и ТLR4-сигнальные пути; угнетения продукции провоспалительных цитокинов (ФHОα, ИЛ-1, ИЛ-6, ИЛ-8); стимулирования продукции противовоспалительных цитокинов (ИЛ-2, ИЛ-10. ИЛ-12). Глицирризиновая кислота ингибирует 11β-оксистероиддегидрогеназу, что способствует повышению эндогенного кортизола в крови (псевдокортикостероидный эффект).\u003Cbr\u003E\nВлияние на фиброгенез связано с уменьшением экспрессии гена коллагена 1-го типа и снижением продукции коллагена звездчатыми клетками печени (клетками Ито), а также разрушением активированных клеток Ито через систему натуральных киллеров, что способствует замедлению прогрессирования фиброза. Подавляет репродукцию вирусов в печени и других органах за счет стимуляции продукции интерферонов, повышения фагоцитоза, увеличения активности естественных клеток-киллеров.\u003Cbr\u003E\nПри поражениях кожи за счет противовоспалительного действия ограничивает распространение процесса и способствует регрессу заболевания. Фосфатидилхолин (действующее вещество фосфолипидов) является основным структурным элементом клеточных и внутриклеточных мембран, восстанавливает их структуру и функции при повреждении, оказывая мембраностабилизирующее действие. Нормализует белковый и липидный обмены, предотвращает потерю гепатоцитами ферментов и других активных веществ, способствует восстановлению функций печени.\u003Cbr\u003E\nГлицирризиновая кислота. После перорального приема в кишечнике под влиянием фермента β-глюкуронидазы, продуцируемого бактериями нормальной микрофлоры, из глицирризиновой кислоты образуется активный метаболит - β-глицирретовая кислота, которая всасывается в системный кровоток. В крови β-глицирретовая кислота связывается с альбумином и практически полностью транспортируется в печень. Выделение β-глицирретовой кислоты происходит преимущественно с желчью, в остаточном количестве - с мочой. По экспериментальным данным, фосфолипиды улучшают липофильные свойства глицирризиновой кислоты, увеличивая интенсивность и скорость ее всасывания более чем в 2 раза.\u003Cbr\u003E\nФосфатидилхолин. Более 90% принятых внутрь фосфолипидов всасывается в тонкой кишке. Большая часть их расщепляется фосфолипазой А до 1-ацетил-лизофосфатидилхолина, 50% которого подвергается обратному ацетилированию в полиненасыщенный фосфатидилхолин в процессе всасывания в слизистой оболочке кишечника. Полиненасыщенный фосфатидилхолин с током лимфы попадает в кровь, откуда, главным образом, в связанном с липопротеинами высокой плотности виде поступает в печень. Фармакокинетика у людей изучалась с помощью диленолеил фосфатидилхолина с радиоактивной меткой - 3Н (холиновая часть) и 14С (остаток линолевой кислоты). Максимальная концентрация 3Н достигается через 6-24 часа, составляя 19,9% от назначенной дозы; 14С - через 4-12 часов, составляя 27,9%.\u003Cbr\u003E\nПериод полувыведения холинового компонента равен 66 часам, остатка линолевой кислоты - 32 часам. В кале обнаруживается 2% 3Н и 4,5% - 14С; в моче - 6% 3Н и минимальное количество 14С. Оба изотопа всасываются в кишечнике более чем на 90%."},{"name":"Фармакологическая группа","value":"гепатопротекторы"},{"name":"Форма выпуска","value":"капсулы"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 12 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей месте при температуре не выше 25°C. Срок годности - 3 года.\u003Cbr\u003E"},{"name":"Передозировка","value":"В настоящее время случаи передозировки препарата Фосфоглив не зарегистрированы.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан при беременности и в период грудного вскармливания (данных по эффективности и безопасности недостаточно)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат не оказывает негативного влияния на способность управлять транспортными средствами и выполнять другую работу, требующую повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"В случае повышения артериального давления следует прекратить прием препарата и обратиться к врачу.\u003Cbr\u003EС осторожностью следует назначать препарат пациентам с портальной гипертензией, артериальной гипертензией. При наличии данных заболеваний перед началом препарата необходимо проконсультироваться с врачом. \u003Cbr\u003E"},{"name":"Взаимодействие","value":"Лекарственное взаимодействие препарата Фосфоглив не описано."},{"name":"Регистрационный номер","value":"P N002528/01"},{"name":"Дата государственной регистрации","value":"09.01.2023"},{"name":"Владелец регистрационного удостоверения","value":"Фармстандарт-Лексредства"},{"name":"Изготовитель","value":"Фармстандарт-Лексредства"},{"name":"Фасовщик","value":"Фармстандарт-Лексредства"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Фосфоглив"},{"name":"Срок годности","value":"37 мес."}]}],"transitionId":"tr_7617145482442350584"}}}}
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  • Гепатрин капс., 120 шт.
    –10 %
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    Гепатрин капс., 120 шт.

    Рейтинг товара: 4.8 из 5
    на основе 870 оценок
    Цена 895 ₽ вместо 1 000
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  • Фосфоглив капс., 96 шт.
    –1 %
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    Фосфоглив капс., 96 шт.

    Рейтинг товара: 4.8 из 5
    на основе 78 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 125 ₽ вместо 1 136
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  • Эссенциале форте Н капс., 300 мг, 30 шт.
    –1 %
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    Эссенциале форте Н капс., 300 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 247 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 751 ₽ вместо 759
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  • Овесол таб. п/о, 40 шт.
    –10 %
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    Овесол таб. п/о, 40 шт.

    Рейтинг товара: 4.9 из 5
    на основе 272 оценки
    Цена 387 ₽ вместо 430
    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  • Эссенциальные фосфолипиды Макси формула капс., 1.4 г, 60 шт., 1 уп.
    ВАМ–42 %
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    Эссенциальные фосфолипиды Макси формула капс., 1.4 г, 60 шт., 1 уп.

    Рейтинг товара: 4.5 из 5
    на основе 85 оценок
    Цена 475 ₽ вместо 824
    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фосфолипиды Макси формула капс., 1.4 г, 60 шт., 1 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  • Фосфоглив форте капс., 65 мг+300 мг, 50 шт.
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    Фосфоглив форте капс., 65 мг+300 мг, 50 шт.

    Рейтинг товара: 4.8 из 5
    на основе 12 оценок
    Цена 1 237 ₽
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  • Фосфоглив Урсо капс., 35 мг+250 мг, 50 шт.
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    Фосфоглив Урсо капс., 35 мг+250 мг, 50 шт.

    Рейтинг товара: 5 из 5
    на основе 19 оценок
    Цена 1 005 ₽
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  • Эссливер форте капс., 30 шт., 1 уп.
    –1 %
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    Эссливер форте капс., 30 шт., 1 уп.

    Рейтинг товара: 3.7 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 707 ₽ вместо 714
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  • Гептрал таб. п/о кш/раств., 400 мг, 20 шт.
    –1 %
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    Гептрал таб. п/о кш/раств., 400 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 251 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 844 ₽ вместо 1 863
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  • Хофитол таб. п/о, 60 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-s1wfjmx10al/toggleWishlist":{"skuId":"228106994","productId":1400799557,"offerId":"dWZ6kRfOYQaUIJW_PYdK5w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ5eiMg9WYst49EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIxYL6mwUQ8sXibBjY4NAHINrZwQc=","sign":"j9qodQXQRFd/1k7tQzcg34f+/MYwiWElycU1BIVlW38="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-s1wfjmx10al/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Хофитол таб. п/о, 60 шт.

    Рейтинг товара: 4.9 из 5
    на основе 167 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 501 ₽ вместо 506
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  • Лив-52 таб., 100 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-76g2iz6837/toggleWishlist":{"skuId":"228007818","productId":1778171087,"offerId":"t5hvVwrwKXuqRo5vSuBNfQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ5eiMg9WYst49EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIz/nyzwYQir/cbBjVyKMIINrZwQc=","sign":"pz3wehybzQp0ysoEOBDwTkiLpIQ9+EY1E4x8lhrwArE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-76g2iz6837/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лив-52 таб., 100 шт.

    Рейтинг товара: 4.9 из 5
    на основе 62 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 475 ₽ вместо 480
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Инструкция

Показания к применению

— жировая дегенерация печени (гепатоз);
— другие поражения печени (алкогольные, токсические, в т.ч. лекарственные);
— в составе комплексной терапии вирусных гепатитов, цирроза печени, и псориаза.

Противопоказания

— антифосфолипидный синдром;
— беременность (данных по эффективности и безопасности недостаточно);
— период лактации (данных по эффективности и безопасности недостаточно);
— детский возраст до 12 лет;
— повышенная чувствительность к глицирризиновой кислоте, фосфатидилхолину или другим компонентам препарата.

Способ применения и дозы

Препарат принимают внутрь во время еды. Капсулы следует проглатывать, не разжевывая, запивая небольшим количеством жидкости.
Взрослым и детям старше 12 лет назначают по 2 капс. 3 раза/сут.
Длительность применения может составлять до 6 мес, в среднем - 3 мес.
Полная инструкция
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Фосфоглив капс.
Фосфоглив капс., 50 шт.
4.9
(113)
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27 вопросов
Инструкция

Цена с картой Яндекс Пэй:651 ₽

Скидка: 11%
–11 %
Вместо: 658 ₽730 ₽
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4.9
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У продавца:113 оценок·18 отзывов
У всех продавцов:611 оценок·178 отзывов
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user avatar
Месяц назад • nadicheva70 • Куплен на Маркете
Достоинства: Дешевле чем в аптеке,доставка прям домой 🥰
Недостатки: Нет
user avatar
9 месяцев назад • Юлия Тремасова • Куплен на Маркете
Достоинства: отличный препарат,хорошего качества,главное помогает моей маме после химии только он
Недостатки: их просто нету
Комментарий: спасибо большое производителю и Яндекс Маркет
user avatar
3 недели назад • светлана р. • Куплен на Маркете
Достоинства: препарат хороший
Недостатки: нет
Комментарий: препарат оценила,принимаю 3 недели..всё отлично
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