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Зиртек капли д/вн. приема, 10 мг/мл, 20 мл

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Коротко о товаре

Артикул Маркета
326466399
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 месяцев
Инструкция
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тошнота, боли в животе, диарея, нарушение функции печени (повышение уровня трансаминаз, ЩФ, ГГТ, билирубина).\u003Cbr\u003EСо стороны мочевыделительной системы: расстройство мочеиспускания, энурез.\u003Cbr\u003EАллергические реакции: зуд, сыпь, крапивница, ангионевротический отек, повышенная чувствительность, вплоть до развития анафилактического шока.\u003Cbr\u003EСо стороны обмена веществ: увеличение массы тела.\u003Cbr\u003EПрочие: усталость, астения, недомогание, отек.\u003Cbr\u003EПобочные эффекты развиваются в очень редких случаях."},{"name":"Фармакологическое действие","value":"Цетиризин - активное вещество препарата Зиртек - является метаболитом гидроксизина, относится к группе конкурентных антагонистов гистамина и блокирует H1-гистаминовые рецепторы.\u003Cbr\u003EВ дополнение к антигистаминному эффекту цетиризин предупреждает развитие и облегчает течение аллергических реакций: в дозе 10 мг один или два раза в день ингибирует позднюю фазу агрегации эозинофилов в коже и конъюнктиве пациентов, подверженных атопии."},{"name":"Фармакологическая группа","value":"противоаллергическое средство - H1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"капли для приема внутрь"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 6 месяцев"},{"name":"Условия хранения","value":"При температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы, наблюдаемые после явной передозировки препараты, влияли на центральную нервную систему или были связаны с возможным антихолинергическим эффектом. Симптомы, которые наблюдались после приема по меньшей мере пятикратного количества рекомендуемой суточной дозы, включали следующее: спутанность сознания, диарея, утомляемость, головная боль, недомогание, мидриаз, зуд, беспокойство, седативный эффект, сонливость, ступор, тахикардия, тремор, задержка мочи.\u003Cbr\u003EЛечение:\u003Cbr\u003EСпецифического антидота нет.\u003Cbr\u003EВ случае передозировки рекомендуется симптоматическое или поддерживающее лечение. Промывание желудка и/или приём активированного угля может быть эффективным, если передозировка произошла недавно. Цетиризин частично выводится при диализе.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Данные по применению цетиризина во время беременности ограничены (300-1000 исходов беременности). Однако не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью.\u003Cbr\u003EЭкспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и постнатальное развитие.\u003Cbr\u003EПри беременности назначение цетиризина возможно после консультации с врачом, в случае если предполагаемая польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EНе следует применять цетиризин во время грудного вскармливания, т.к. цетиризин экскретируется с грудным молоком. Цетиризин выделяется в грудное молоко в количестве 25-90 % от концентрации в плазме крови, в зависимости от времени отбора проб после приема препарата.\u003Cbr\u003EНежелательные реакции, связанные с цетиризином, могут наблюдаться у грудных детей.\u003Cbr\u003EВ период грудного вскармливания применяют после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для ребенка.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии на фертильность человека ограничены, однако отрицательного влияния на фертильность в исследованиях на животных не выявлено.\u003Cbr\u003EПеред применением препарата, если Вы беременны, или предполагаете, что Вы могли бы быть беременной, или планируете беременность, необходимо проконсультироваться с врачом.\u003Cbr\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При объективной оценке способности к вождению автотранспорта и управлению механизмами достоверно не выявлено каких-либо нежелательных явлений при приеме препарата в рекомендуемой дозе. Однако пациентам с проявлениями сонливости на фоне приема препарата целесообразно воздерживаться от управления автомобилем, занятий потенциально опасными видами деятельности или управлением механизмами, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Ввиду потенциального угнетающего влияния на центральную нервную систему следует соблюдать осторожность при назначении препарата Зиртек детям в возрасте от 6 мес до 1 года при наличии следующих факторов риска возникновения синдрома внезапной детской смерти, таких, как (но не ограничиваясь этим списком):\u003Cbr\u003E- синдром апноэ во сне или синдром внезапной детской смерти детей грудного возраста у брата или сестры;\u003Cbr\u003E- злоупотребление матери наркотиками или курением во время беременности;\u003Cbr\u003E- молодой возраст матери (19 лет и моложе);\u003Cbr\u003E- злоупотребление курением няни, ухаживающей за ребенком (одна пачка сигарет в день или более);\u003Cbr\u003E- дети, регулярно засыпающие лицом вниз и которых не укладывают на спину;\u003Cbr\u003E- недоношенные (гестационный возраст менее 37 недель) или рожденные с недостаточной массой тела (ниже 10-го перцентиля от гестационного возраста) дети;\u003Cbr\u003E- при совместном приеме препаратов, оказывающих угнетающее влияние на центральную нервную систему.\u003Cbr\u003EВ состав препарата входят вспомогательные вещества метилпарабензол и пропилпарабензол, которые могут вызвать аллергические реакции, в том числе замедленного типа.\u003Cbr\u003EУ пациентов с повреждением спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов к задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи.\u003Cbr\u003EУ пациентов с почечной недостаточностью режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EИз-за возможного снижения функции почек у пациентов пожилого возраста режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EРекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем, так как цетиризин может привести к повышенной сонливости.\u003Cbr\u003EОсторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что блокаторы H1-гистаминовых рецепторов ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EВнимательно прочтите инструкцию перед тем, как начать применение препарата. Сохраните инструкцию, она может понадобиться вновь. Если у Вас возникли вопросы, обратитесь к врачу. Лекарственное средство, которым Вы лечитесь предназначено лично Вам, и его не следует передавать другим лицам, поскольку оно может причинить им вред даже при наличии тех же симптомов, что и у Вас.\u003Cbr\u003E- Хроническая почечная недостаточность (при клиренсе креатинина \u003E 10 мл в мин требуется коррекция режима дозирования);\u003Cbr\u003E- пациенты пожилого возраста (при возрастном снижении клубочковой фильтрации);\u003Cbr\u003E- эпилепсия и пациенты с повышенной судорожной готовностью;\u003Cbr\u003E- пациенты с предрасполагающими факторами к задержке мочи;\u003Cbr\u003E- детский возраст до 1 года;\u003Cbr\u003E- при одновременном употреблении с алкоголем;\u003Cbr\u003E- период грудного вскармливания;\u003Cbr\u003E- беременность.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Одновременное применение с азитромицином, циметидином, эритромицином, кетоконазолом или псевдоэфедрином не влияет на фармакокинетические параметры цетиризина. Фармакокинетических взаимодействий не наблюдалось. Согласно испытаниям in vitro, цетиризин не влияет на эффект связывания белка варфарина.\u003Cbr\u003EОдновременный прием азитромицина, эритромицина, кетоконазола, теофиллина и псевдоэфедрина не выявил существенных изменений в клинических лабораторных показателях, жизненно важных функциях и ЭКГ.\u003Cbr\u003EВ исследовании с одновременным приемом теофиллина (400 мг в день) и цетиризина (20 мг в день) было обнаружено незначительное, но статистически достоверное повышение 24-часовой AUC (площади под кривой) на 19% для цетиризина и на 11% для теофиллина. Кроме того, максимальные уровни в плазме крови увеличились до 7,7% и 6,4% соответственно для цетиризина и теофиллина. Одновременно клиренс цетиризина уменьшился на -16%, а также на - 10% в случае теофиллина, когда цетиризин принимали пациенты, которые ранее получали лечение теофиллином. Тем не менее, предварительное лечение цетиризином не оказало существенного влияния на фармакокинетические параметры теофиллина.\u003Cbr\u003EПосле однократного приема цетиризина в дозе 10 мг эффект алкоголя (0,8%о) значительно не усиливался; статистически значимое взаимодействие с 5 мг диазепама было доказано в одном из 16 психометрических тестов.\u003Cbr\u003EОдновременный прием 10 мг цетиризина в день с глипизидом привел к незначительному снижению показателей глюкозы. Этот эффект не имеет клинического значения. Тем не менее, рекомендуется раздельный прием - глипизид утром и цетиризин вечером.\u003Cbr\u003EСтепень всасывания цетиризина не снижается при одновременном приеме пищи, хотя всасывание замедляется на 1 час,\u003Cbr\u003EВ исследовании с многократным приемом ритонавира (600 мг два раза в день) и цетиризина (10 мг в день) степень экспозиции цетиризина была увеличена примерно на 40%, в то время как, экспозиция ритонавира незначительно изменилась (-11%) вследствие сопутствующего приема цетиризина.\u003Cbr\u003EЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Зиртек проконсультируйтесь с врачом.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"П N011930/01"},{"name":"Дата государственной регистрации","value":"10.03.2020"},{"name":"Владелец регистрационного удостоверения","value":"UCB Farchim S.A.","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34324371:35649313","7893318:16228924"]}}},{"name":"Изготовитель","value":"Aesica"},{"name":"Фасовщик","value":"Aesica"},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Зиртек","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["17796364:17877894"]}}},{"name":"Срок годности","value":"59 мес."}]}},"fullSpecsGrouped":{"16193895207927167302":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"глаза, дыхательная система, иммунная система, носовая полость"},{"name":"Назначение","value":"аллергический конъюнктивит, аллергический ринит, крапивница"},{"name":"Показания к применению","value":"Применение препарата показано у взрослых и детей с 6 месяцев для облегчения: назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы; симптомов хронической идиопатической крапивницы.\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!\u003Cbr\u003E"},{"name":"Противопоказания","value":"- Повышенная чувствительность к цетиризину, гидроксизину или любым производным пиперазина, а также другим компонентам препарата;\u003Cbr\u003E- терминальная стадия почечной недостаточности (клиренс креатинина \u003C 10 мл/мин);\u003Cbr\u003E- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности применения препарата Зиртек."},{"name":"Состав","value":"Активное вещество: цетиризина дигидрохлорид 10 мг/мл.\u003Cbr\u003EВспомогательные вещества: глицерол 250,00 мг, пропиленгликоль 350,00 мг, сахаринат натрия 10,00 мг, метилпарабензол 1,35 мг, пропилпарабензол 0,15 мг, ацетат натрия 10,00 мг, ледяная уксусная кислота 0,53 мг, вода очищенная до 1,00 мл."},{"name":"Действующее вещество","value":"Цетиризин"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПринимать препарат следует вечером, т.к. симптомы становятся более выраженными вечером.\u003Cbr\u003EПри необходимости препарат Зиртек можно запить стаканом воды.\u003Cbr\u003EПрепарат Зиртек® можно принимать независимо от приёма пищи.\u003Cbr\u003EВзрослым\u003Cbr\u003E10 мг (20 капель) 1 раз в день.\u003Cbr\u003EАльтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).\u003Cbr\u003EДети\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!\u003Cbr\u003EДети от 6 до 12 месяцев\u003Cbr\u003E2,5 мг (5 капель) 1 раз в день.\u003Cbr\u003EДети от 1 года до 6 лет\u003Cbr\u003E2,5 мг (5 капель) 2 раза в день утром и вечером\u003Cbr\u003EПродолжительность лечения не должна превышать 4 недель.\u003Cbr\u003EДети от 6 до 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день\u003Cbr\u003EПродолжительность лечения не должна превышать 4 недель.\u003Cbr\u003EАльтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).\u003Cbr\u003EДети старше 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день\u003Cbr\u003EИногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.\u003Cbr\u003EДетям с почечной недостаточностью дозу корректируют с учетом КК и массы тела.\u003Cbr\u003EОтдельные группы пациентов\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EИз-за возможного снижения функции почек режим дозирования препарата следует корректировать (см. подраздел \"Пациенты с почечной недостаточностью\" раздела \"Способ применения и дозы\".\u003Cbr\u003EПациенты с почечной недостаточностью\u003Cbr\u003EПоскольку препарат Зиртек выводится из организма в основном почками, при невозможности альтернативного лечения пациентов с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины клиренса креатинина - КК).\u003Cbr\u003EКК для мужчин можно рассчитать, исходя из концентрации сывороточного креатинина, по следующей формуле:\u003Cbr\u003EКК(мл/мин)= [140 - возраст (годы)] х масса тела (кг) / 72 х ККсыворот (мг/дл)\u003Cbr\u003EКК для женщин можно рассчитать, умножив полученное значение на коэффициент 0,85.\u003Cbr\u003EУ пациентов с нарушением только функции печени коррекции режима дозирования не требуется.\u003Cbr\u003E Если после лечения улучшения не наступает или появляются новые симптомы, необходимо проконсультироваться с врачом.\u003Cbr\u003EПрименяйте препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции.\u003Cbr\u003E"},{"name":"Побочные действия","value":"Со стороны системы кроветворения: тромбоцитопения.\u003Cbr\u003EСо стороны нервной системы: сонливость, головокружение, головная боль, агрессия, возбуждение, замешательство, депрессия, галлюцинации, бессонница, тик, судороги, дискинезия, дистония, парестезия, обморок, тремор.\u003Cbr\u003EСо стороны органа зрения: нарушение аккомодации, нечеткое зрение, нистагм.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: тахикардия.\u003Cbr\u003EСо стороны дыхательной системы: ринит, фарингит.\u003Cbr\u003EСо стороны пищеварительной системы: сухость во рту, тошнота, боли в животе, диарея, нарушение функции печени (повышение уровня трансаминаз, ЩФ, ГГТ, билирубина).\u003Cbr\u003EСо стороны мочевыделительной системы: расстройство мочеиспускания, энурез.\u003Cbr\u003EАллергические реакции: зуд, сыпь, крапивница, ангионевротический отек, повышенная чувствительность, вплоть до развития анафилактического шока.\u003Cbr\u003EСо стороны обмена веществ: увеличение массы тела.\u003Cbr\u003EПрочие: усталость, астения, недомогание, отек.\u003Cbr\u003EПобочные эффекты развиваются в очень редких случаях."},{"name":"Фармакологическое действие","value":"Цетиризин - активное вещество препарата Зиртек - является метаболитом гидроксизина, относится к группе конкурентных антагонистов гистамина и блокирует H1-гистаминовые рецепторы.\u003Cbr\u003EВ дополнение к антигистаминному эффекту цетиризин предупреждает развитие и облегчает течение аллергических реакций: в дозе 10 мг один или два раза в день ингибирует позднюю фазу агрегации эозинофилов в коже и конъюнктиве пациентов, подверженных атопии."},{"name":"Фармакологическая группа","value":"противоаллергическое средство - H1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"капли для приема внутрь"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 6 месяцев"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы, наблюдаемые после явной передозировки препараты, влияли на центральную нервную систему или были связаны с возможным антихолинергическим эффектом. Симптомы, которые наблюдались после приема по меньшей мере пятикратного количества рекомендуемой суточной дозы, включали следующее: спутанность сознания, диарея, утомляемость, головная боль, недомогание, мидриаз, зуд, беспокойство, седативный эффект, сонливость, ступор, тахикардия, тремор, задержка мочи.\u003Cbr\u003EЛечение:\u003Cbr\u003EСпецифического антидота нет.\u003Cbr\u003EВ случае передозировки рекомендуется симптоматическое или поддерживающее лечение. Промывание желудка и/или приём активированного угля может быть эффективным, если передозировка произошла недавно. Цетиризин частично выводится при диализе.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Данные по применению цетиризина во время беременности ограничены (300-1000 исходов беременности). Однако не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью.\u003Cbr\u003EЭкспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и постнатальное развитие.\u003Cbr\u003EПри беременности назначение цетиризина возможно после консультации с врачом, в случае если предполагаемая польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EНе следует применять цетиризин во время грудного вскармливания, т.к. цетиризин экскретируется с грудным молоком. Цетиризин выделяется в грудное молоко в количестве 25-90 % от концентрации в плазме крови, в зависимости от времени отбора проб после приема препарата.\u003Cbr\u003EНежелательные реакции, связанные с цетиризином, могут наблюдаться у грудных детей.\u003Cbr\u003EВ период грудного вскармливания применяют после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для ребенка.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии на фертильность человека ограничены, однако отрицательного влияния на фертильность в исследованиях на животных не выявлено.\u003Cbr\u003EПеред применением препарата, если Вы беременны, или предполагаете, что Вы могли бы быть беременной, или планируете беременность, необходимо проконсультироваться с врачом.\u003Cbr\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При объективной оценке способности к вождению автотранспорта и управлению механизмами достоверно не выявлено каких-либо нежелательных явлений при приеме препарата в рекомендуемой дозе. Однако пациентам с проявлениями сонливости на фоне приема препарата целесообразно воздерживаться от управления автомобилем, занятий потенциально опасными видами деятельности или управлением механизмами, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Ввиду потенциального угнетающего влияния на центральную нервную систему следует соблюдать осторожность при назначении препарата Зиртек детям в возрасте от 6 мес до 1 года при наличии следующих факторов риска возникновения синдрома внезапной детской смерти, таких, как (но не ограничиваясь этим списком):\u003Cbr\u003E- синдром апноэ во сне или синдром внезапной детской смерти детей грудного возраста у брата или сестры;\u003Cbr\u003E- злоупотребление матери наркотиками или курением во время беременности;\u003Cbr\u003E- молодой возраст матери (19 лет и моложе);\u003Cbr\u003E- злоупотребление курением няни, ухаживающей за ребенком (одна пачка сигарет в день или более);\u003Cbr\u003E- дети, регулярно засыпающие лицом вниз и которых не укладывают на спину;\u003Cbr\u003E- недоношенные (гестационный возраст менее 37 недель) или рожденные с недостаточной массой тела (ниже 10-го перцентиля от гестационного возраста) дети;\u003Cbr\u003E- при совместном приеме препаратов, оказывающих угнетающее влияние на центральную нервную систему.\u003Cbr\u003EВ состав препарата входят вспомогательные вещества метилпарабензол и пропилпарабензол, которые могут вызвать аллергические реакции, в том числе замедленного типа.\u003Cbr\u003EУ пациентов с повреждением спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов к задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи.\u003Cbr\u003EУ пациентов с почечной недостаточностью режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EИз-за возможного снижения функции почек у пациентов пожилого возраста режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EРекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем, так как цетиризин может привести к повышенной сонливости.\u003Cbr\u003EОсторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что блокаторы H1-гистаминовых рецепторов ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EВнимательно прочтите инструкцию перед тем, как начать применение препарата. Сохраните инструкцию, она может понадобиться вновь. Если у Вас возникли вопросы, обратитесь к врачу. Лекарственное средство, которым Вы лечитесь предназначено лично Вам, и его не следует передавать другим лицам, поскольку оно может причинить им вред даже при наличии тех же симптомов, что и у Вас.\u003Cbr\u003E- Хроническая почечная недостаточность (при клиренсе креатинина \u003E 10 мл в мин требуется коррекция режима дозирования);\u003Cbr\u003E- пациенты пожилого возраста (при возрастном снижении клубочковой фильтрации);\u003Cbr\u003E- эпилепсия и пациенты с повышенной судорожной готовностью;\u003Cbr\u003E- пациенты с предрасполагающими факторами к задержке мочи;\u003Cbr\u003E- детский возраст до 1 года;\u003Cbr\u003E- при одновременном употреблении с алкоголем;\u003Cbr\u003E- период грудного вскармливания;\u003Cbr\u003E- беременность.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Одновременное применение с азитромицином, циметидином, эритромицином, кетоконазолом или псевдоэфедрином не влияет на фармакокинетические параметры цетиризина. Фармакокинетических взаимодействий не наблюдалось. Согласно испытаниям in vitro, цетиризин не влияет на эффект связывания белка варфарина.\u003Cbr\u003EОдновременный прием азитромицина, эритромицина, кетоконазола, теофиллина и псевдоэфедрина не выявил существенных изменений в клинических лабораторных показателях, жизненно важных функциях и ЭКГ.\u003Cbr\u003EВ исследовании с одновременным приемом теофиллина (400 мг в день) и цетиризина (20 мг в день) было обнаружено незначительное, но статистически достоверное повышение 24-часовой AUC (площади под кривой) на 19% для цетиризина и на 11% для теофиллина. Кроме того, максимальные уровни в плазме крови увеличились до 7,7% и 6,4% соответственно для цетиризина и теофиллина. Одновременно клиренс цетиризина уменьшился на -16%, а также на - 10% в случае теофиллина, когда цетиризин принимали пациенты, которые ранее получали лечение теофиллином. Тем не менее, предварительное лечение цетиризином не оказало существенного влияния на фармакокинетические параметры теофиллина.\u003Cbr\u003EПосле однократного приема цетиризина в дозе 10 мг эффект алкоголя (0,8%о) значительно не усиливался; статистически значимое взаимодействие с 5 мг диазепама было доказано в одном из 16 психометрических тестов.\u003Cbr\u003EОдновременный прием 10 мг цетиризина в день с глипизидом привел к незначительному снижению показателей глюкозы. Этот эффект не имеет клинического значения. Тем не менее, рекомендуется раздельный прием - глипизид утром и цетиризин вечером.\u003Cbr\u003EСтепень всасывания цетиризина не снижается при одновременном приеме пищи, хотя всасывание замедляется на 1 час,\u003Cbr\u003EВ исследовании с многократным приемом ритонавира (600 мг два раза в день) и цетиризина (10 мг в день) степень экспозиции цетиризина была увеличена примерно на 40%, в то время как, экспозиция ритонавира незначительно изменилась (-11%) вследствие сопутствующего приема цетиризина.\u003Cbr\u003EЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Зиртек проконсультируйтесь с врачом.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"П N011930/01"},{"name":"Дата государственной регистрации","value":"10.03.2020"},{"name":"Владелец регистрационного удостоверения","value":"UCB Farchim S.A."},{"name":"Изготовитель","value":"Aesica"},{"name":"Фасовщик","value":"Aesica"},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Зиртек"},{"name":"Срок годности","value":"59 мес."}]}],"transitionId":"tr_16498561666224665925"}}}}
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174 ₽

  • 11 июня, курьер Маркета • 249 ₽
  • Завтра, самовывоз • 0 ₽
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  • Цетрин таб. п/о плен., 10 мг, 20 шт.
    –1 %
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    Цетрин таб. п/о плен., 10 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 146 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 160 ₽ вместо 162
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п/о плен., 10 мг, 20 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  • Зодак таб. п/о плен., 10 мг, 30 шт.
    –17 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-fnm2lmbvtjg/toggleWishlist":{"skuId":"186887758","productId":1417730422,"offerId":"Z7uJo0efsPjzcJ-HJl-PGw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ2oysv7KA7+JeEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI9rKDpAUQztyOWRj6g4ISINbZwQc=","sign":"rn3R7WD6Xg9zjl29kexsuS9yIKSvqQj/skX2zobrOCc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-fnm2lmbvtjg/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Зодак таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 79 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 266 ₽ вместо 269
    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таб. п/о плен., 10 мг, 30 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  • Фенистил капли д/вн. приема, 0.1%, 20 мл
    –1 %
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    Фенистил капли д/вн. приема, 0.1%, 20 мл

    Рейтинг товара: 4.8 из 5
    на основе 20 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 577 ₽ вместо 583
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  • Зиртек таб. п/о плен., 10 мг, 30 шт.
    –1 %
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    Зиртек таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 22 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 291 ₽ вместо 294
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  • Зиртек таб. п/о плен. (блистер), 10 мг, 20 шт.
    –13 %
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    Зиртек таб. п/о плен. (блистер), 10 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 20 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 236 ₽ вместо 238
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  • Цетиризин капли д/вн. приема, 10 мг/мл, 10 мл
    –1 %
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    Цетиризин капли д/вн. приема, 10 мг/мл, 10 мл

    Рейтинг товара: 4.2 из 5
    на основе 10 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 105 ₽ вместо 106
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  • Супрастинекс капли д/вн. приема фл., 5 мг/мл, 20 мл
    –1 %
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    Супрастинекс капли д/вн. приема фл., 5 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 414 ₽ вместо 418
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  • Супрастин таб., 25 мг, 1 мл, 20 шт.
    –12 %
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    Супрастин таб., 25 мг, 1 мл, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 143 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 146 ₽ вместо 147
    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таб., 25 мг, 1 мл, 20 шт.","label":"tgqtj7hlqol","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":1538707,"key":"img_id8441917756753349298.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96WFVmZtSFtMyZQgwYujECEA4_RBXD3v21PJNtmyVuji8zEjvIuFiZYj3IpQB5Ag2erheiD4yhZbFTiOokYGPRybwDArTvP3UH0Sivlgx_ft09g1MU9CK08YPBNO_2vPExXcYQjZDcRCrSUt6a0Om-nu7iNuVcQxtDbjCYBnrWjaVqvx8d6bQM939rH8O44mY2XVIyJwG-VPYjHrr7pwm6w8EvzTFwbh5Sb1lVfQ8tra2-S5PSEw5FmV0zn1HYGONRYf549PgEgW7nAlerZQWQKL7pM9fmZPn8Z_UaGi5HoxKrJZHg69N-78DFaSfhz7X58OuIcxd7O4BqjumtwCISx0Mzts8_yMoDBKzaajzDR_Ug-JoQSwHLB41KdhceSnVGPj33Dn4HQfy4vVDu115PwLZp-dAaNVX6TTN113yqjqgkKdqpM8-Zym-k56S0Zhen09u-S7RxMjv2FIpIW0x58ulL_b81h4MyKyDnATACJyNgYQEGUPvKh0joPMbNFF0xcK3whZMKzFHGAYokEEddbO81LvNg0_7EfSEmKpb7oHeb-RkcutIfqlPhLtOcD1xUtbsI6-dIf9e06hunF5yIaOZS1--m3grMrYGFboETLciTdBdfvxjLpI4SyBf6aEyLy-91x7Bj7ptYYgdhjhd2xFJX3N61NFvLL-MQH_-hUbN-_5-XED-IbIA9rixuxTSMjZk9KlVeLOxSU19rqGx0E4TaF0tTOBGo97tmAfRFSyWKALTMFNXVzPntXGyTHrfl0dO9zIxkl23_vXSvtY3MIDrATRDaTFSHuwoiva0G1-Jpo5VQewwe4oLlsUFAY1Fyqvihl6wJOKaFw80ZTWoHbgsD-RyE-43QMn4EbQIvxmDH3XF77fO0pLkn72_fH4By3zPw46Sdufu0NpEg8vDPEoaqql9ZReusnhHixV6Zx0VpmVrljgj2hy4SLPKIffKl1qtjQf0CqkFcF0vx6ChMV1_DzK6KkIjuwop3leMtyNSPnGBfvFfQUY0U8jQ_6yvjM_Feft72DmjvcRf6MQpy6knbhPdxbw8Pga2uf9VbY9lq65RLp9uyyOb6cP-5KwM7iov7dMDKY0Zr0IGgTuCP6zL4Oefy3a-VsHzmC-CB8kWp-SBnHALJn6YTlRxtT68MYxcdIjf3TZBVoaJAvVqbE2yfnBjVueC3CZCzblkc41hygjP7wuF_BE1gjT_s1exlAUY_t4jcTKL520uzsiDhyMxuyEcnuZggPRJUboYqqCsV-0IP4tS5jC-yHkZJD0wo0bdOvl0YFIk-qiDFAQweZnlhVpT6RXUhBsfY8P-eSvrERVZR5HVzpPkr2QmO98pg1RzcjK5bXCjTOHwOA-eWK_IN7x_J3yRHUMQPVyoRpwoluykWb-NhcuvEhy3r0lJjk_YSMGGLdKsirI9pUQbDKUovdo98a3nAbMrwzuIb0EZy18VEKOpj_WqCJjXPa-RezHLdUbKWs0uc0giqDcBU2gZhl2eRVwzHRkjQdc7gk83zx4uxVVSohtOMOcZzjDFP5_YU8v2xrfktuWurHH9ou8uKWsOAPExo6BA60nTFpX7n0uJSOjf9M0Ga33P6SQHXH9n9vIBQc67tkOxdNf4dYtddDfxiNPvDCCp-5-Y1SkVWO75KOZMK1MLKDWJfC1TXpmUYQSsP4ky3CgsWyD8kmsLgTOWIrfwZrwOYLtauMKZ7JNyabdqPuYG2nG3tYCxVgRd-a3iKhouZlhAwTFwZGcleqT0x1GzoCVhY8av2YUQRfyRZ4L78Zsavr1bihesXmhswP3glL6cK2hqxw0ZGq4japndo6n81jX9rTZfatnfH7diIfGkE5y_nCerivtj3PGVF78fAJBxVAVP_WizBVC9jL8i5P0EJ0gX2RKpdsRLKNXrYHH36Jc0iJPWj88QmsxTXrcm3lHAW5_HAFNejNDs1Sg2vUmX_vqSpkUjdatZKi-p-BZsNUjJgxv8Rqw9vMJb1tgAtHPDZGN1BNAjSNov5SpIthOn7JYHPGj0CzKokb7g2WSY7P9DO9JSCSMjBBC8t2rP7rgk27UTmb5Rv465VQrr5Mgwei5rPohzww4V3nptW-Q9a7HkbPlIcbj6THzu2Yf1-re1epRc1_iuxXGdILfGarzqPJRPRBOFwVjilhiC5wRASKrfROoB6Icpj2b5SdyKfLLjL7LQosHwLHoxmWJTt3s2C0j1h4SaIMU9DQMtaxWHp3BG8qnOpU0RPx50aM3F36sqXc-EPMWUuaKbBZZtQsDMsuhe6-_zTiFxzC7HZtPslz8mxhQgHz5CqJwGqMhUPZe5xM9kI62bB_vnbwW8HBMBSh5rxuCiagz58byMJpI2rgntVceM2IC3q7MAH5kWZXwdNHENNhavVXj0rjR8sHzYIORzHVwV9AEIsQz5XqXwypEbKnI0817RatShJcy7Ihsriyr2kNnF5uAO0eDy-rWZ5rTBOQSXgWnvqXwWbLd9TrQOtRBsAFUU3sTEcPj6HoRQ5kFjMZkc-L65Ly9owOli-6jrPTQHlMPGYHn7N9MUACGOepyHvCgnE-UjFvPshT0ZEEutcjvLO5JP33jB_r2Ah0SEnxValU3hQQ0j1nrZwG6TjDYHctItzKT9_F8vdU6kTHWz-_mDeEs4DTCtwJEzdcQ9xHkcUzEtWWL_l700mR75ieiuxOwn-X-dys4zQxY7mZUg5h3NAVsIWSUfnpsIXPFK2KqAwWbXA00ggOw638x8ndpcpQqikdY8rcPt0FmaLk8g4BWlnF1fp_HP2iBvUfc1cx9-eGS55fAdvhKsLt7MfLznOZT5Y04LwzbdT3h7fRTSIbA77bsuzLsSd0tByEPaHtdMVmORDbnDxQ568ebA5wKBvEUcfHx2cMSsLynQr8oLyNxr9S9BL8DUom0swXyy1rf3Bx-5YS-z4NzRORMRc0T3vV7TvDD-LGEZBNeodVqcQE999Cj69iVAa9UA6_KIidx12adTBkr-oHPgQhbCq9AYRqE7HqRDZ7vKday8CWbmKxwowEKVXAtUKPjlRnwUI995T-cSCl3utdgy_c4xFxvZigivZmdYV7_qw8W3MNQA0RA16jK77DNj3NkZ7prYS3YVs7I_jeRUciu1P56tqBfBe77M8BlZQQk9fO1mPnk0LVCJdM_4LOTjH1C-bGm4KVHPGJYlydIKnzoKrIpgVoZZmnAwT-gzuLCBIBIXxqXSSlmPl7IPXJn6SytVa2dqylOjuTjt2KjRP1-bCg4xkuilgyXCxuadRdNMAlM3CFd5cuAG6tGjhxbb3yF5RInKU0edZNZotiJsUvk2iePq7OZUK9TflWZs01WNV2goYsE3FeRqJFE5kCh85oE28fYb-E8GtZzhALvc7lgKx10JksC3IGP-NbzHotoMKNwp_pYHtUEAV5WvoeeKABpKJ2t83SSdl3q_qu5Nr6s4kUJ3Lco-Tsfknnvf_DUhajvCQ,,/b64e=1/sign=270bfccbca4d49301ec81406ab06eed2/keyno=MARKET_1/*","showUid":"17178630694612461231306009","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ2oysv7KA7+JeEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIjrODpAUQ2djQbBiS3dAHINbZwQc=","sign":"jMd9/s+PEaW5XAlQPzbhsBaoNzZE5/rWK9Ms+FGBw48="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ2oysv7KA7+JeEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIjrODpAUQ2djQbBiS3dAHINbZwQc=","sign":"jMd9/s+PEaW5XAlQPzbhsBaoNzZE5/rWK9Ms+FGBw48="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-p6vtlt0w5co/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Цетиризин таб. п/о плен., 10 мг, 10 шт.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zy7vsr8lhr9/toggleWishlist":{"skuId":"454094049","productId":1417730416,"offerId":"BcjgIqXs2ZFBLRg_z8SNwg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ2oysv7KA7+JeEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI8LKDpAUQ4dnD2AEYtNWHBCDW2cEH","sign":"kwrTwAi0cDHzmMen4FAQpmRt2bKtApFZaXIrkBuu1a4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zy7vsr8lhr9/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Цетиризин таб. п/о плен., 10 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 47 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 60 ₽ вместо 61
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  • Солонэкс капли д/вн. приема, 10 мг/мл, 20 мл
    –1 %
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    Солонэкс капли д/вн. приема, 10 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 197 ₽ вместо 199
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Инструкция

Показания к применению

Применение препарата показано у взрослых и детей с 6 месяцев для облегчения: назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы; симптомов хронической идиопатической крапивницы.
Применение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!

Противопоказания

- Повышенная чувствительность к цетиризину, гидроксизину или любым производным пиперазина, а также другим компонентам препарата;
- терминальная стадия почечной недостаточности (клиренс креатинина < 10 мл/мин);
- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности применения препарата Зиртек.

Способ применения и дозы

Внутрь.
Принимать препарат следует вечером, т.к. симптомы становятся более выраженными вечером.
При необходимости препарат Зиртек можно запить стаканом воды.
Препарат Зиртек® можно принимать независимо от приёма пищи.
Взрослым
10 мг (20 капель) 1 раз в день.
Альтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).
Дети
Применение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!
Дети от 6 до 12 месяцев
2,5 мг (5 капель) 1 раз в день.
Дети от 1 года до 6 лет
2,5 мг (5 капель) 2 раза в день утром и вечером
Продолжительность лечения не должна превышать 4 недель.
Дети от 6 до 12 лет
10 мг (20 капель) 1 раз в день
Продолжительность лечения не должна превышать 4 недель.
Альтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).
Дети старше 12 лет
10 мг (20 капель) 1 раз в день
Иногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.
Детям с почечной недостаточностью дозу корректируют с учетом КК и массы тела.
Отдельные группы пациентов
Пациенты пожилого возраста
Из-за возможного снижения функции почек режим дозирования препарата следует корректировать (см. подраздел "Пациенты с почечной недостаточностью" раздела "Способ применения и дозы".
Пациенты с почечной недостаточностью
Поскольку препарат Зиртек выводится из организма в основном почками, при невозможности альтернативного лечения пациентов с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины клиренса креатинина - КК).
КК для мужчин можно рассчитать, исходя из концентрации сывороточного креатинина, по следующей формуле:
КК(мл/мин)= [140 - возраст (годы)] х масса тела (кг) / 72 х ККсыворот (мг/дл)
КК для женщин можно рассчитать, умножив полученное значение на коэффициент 0,85.
У пациентов с нарушением только функции печени коррекции режима дозирования не требуется.
Если после лечения улучшения не наступает или появляются новые симптомы, необходимо проконсультироваться с врачом.
Применяйте препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции.
Полная инструкция
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Зиртек капли д/вн. приема
Зиртек капли д/вн. приема, 10 мг/мл, 20 мл
5.0
(36)
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4 вопроса
Инструкция

174 ₽

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5.0
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У продавца:36 оценок·7 отзывов
У всех продавцов:251 оценка·79 отзывов
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user avatar
Месяц назад • Сергей Д. • Куплен на Маркете
Достоинства: действует, можно разделить 10 капель утром,10 капель вечером , помогает пережить аллергию, точнее её симптомы.
Недостатки: не обнаружено
Комментарий: по 20 капель в день,средство работает
user avatar
5 месяцев назад • Имя скрыто • Куплен на Маркете
Достоинства: Безопасное средство для аллергиков с аллергией на гистамин.Конечно,невкусное,но от аллергии помогает,а это главное.
user avatar
Месяц назад • Артем Голев • Куплен на Маркете
Достоинства: Качественное лекарство. Применяем с года ребенку при необходимости. Помогают.
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