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Описание

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Неванак гл. капли фл.-капельница, 0.1%, 5 мл

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4.7
(9)
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Коротко о товаре

Артикул Маркета
3123929035
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"17935713076245592939":{"specItems":[{"name":"Артикул Маркета","value":"3123929035","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"профилактика и лечение боли и воспаления в послеоперационном периоде экстракции катаракты","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["36476390:36617345"]}}},{"name":"действующее вещество","value":"Непафенак","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27144131:28710386"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"капли"},{"name":"страна-производитель","value":"Бельгия"}]}},"compactSpecs":{"17935713076245592939":{"specItems":[{"name":"Артикул Маркета","value":"3123929035","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Действующее вещество","value":"Непафенак","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27144131:28710386"]}}},{"name":"Возраст","value":"От 18 лет"},{"name":"Форма выпуска","value":"Капли"}]}},"fullSpecs":{"17935713076245592939":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"глаза","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["34045610:34516019"]}}},{"name":"Назначение","value":"профилактика и лечение боли и воспаления в послеоперационном периоде экстракции катаракты","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["36476390:36617345"]}}},{"name":"Показания к применению","value":"Профилактика и лечение послеоперационной боли и воспалительных явлений при хирургических вмешательствах по поводу удаления катаракты."},{"name":"Противопоказания","value":"Индивидуальная гиперчувствительность к компонентам препарата, а также к другим нестероидным противовоспалительным препаратам.\u003Cbr\u003EБронхиальная астма, крапивница, острый ринит, вызванные приемом ацетилсалициловой кислоты или других нестероидных противовоспалительных препаратов.\u003Cbr\u003EВозраст до 18 лет (безопасность и эффективность применения препарата у детей не исследовались)."},{"name":"Состав","value":"Состав 1 мл препарата.\u003Cbr\u003EАктивное вещество: непафенак 1,0 мг.\u003Cbr\u003EВспомогательные вещества: бензалкония хлорид (в виде 50 % раствора) 0,05 мг; карбомер (974Р) 5,0 мг; тилоксапол 0,1 мг; динатрия эдетат 0,1 мг; маннитол 24,0 мг; натрия хлорид 4,0 мг; натрия гидроксид и/или кислота хлористоводородная до доведения pH, вода очищенная до 1 мл."},{"name":"Действующее вещество","value":"Непафенак","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27144131:28710386"]}}},{"name":"Способ применения и дозы","value":"Взрослые, включая пациентов пожилого возраста\u003Cbr\u003E\nПрофилактика и лечение боли и воспаления в послеоперационном периоде экстракции катаракты\u003Cbr\u003E\nПо 1 капле препарата Неванак в конъюнктивальный мешок глаза (глаз) 3 раза в сутки, Лечение начинают за день до хирургического вмешательства по удалению катаракты и продолжают в течение первых 2 недель послеоперационного периода (включая день операции).\u003Cbr\u003E\nЗа 30-120 минут до операции необходимо закапать дополнительную каплю препарата.\u003Cbr\u003E\nЛечение может быть продлено до 3 недель послеоперационного периода по назначению врача.\u003Cbr\u003E\nСнижение риска развития макулярного отека у пациентов с сахарным диабетом в послеоперационном периоде экстракции катаракты\u003Cbr\u003E\nПо 1 капле препарата Неванак в конъюнктивальный мешок глаза (глаз) 3 раза в сутки. Лечение начинают за 1 день до хирургического вмешательства по удалению катаракты, затем продолжают в день операции и в послеоперационный период продолжительностью до 60 дней по назначению врача.\u003Cbr\u003E\nЗа 30-120 минут до операции необходимо закапать дополнительную каплю препарата.\u003Cbr\u003E\nОсобые группы пациентов\u003Cbr\u003E\nПациенты с нарушением функции печени и почек\u003Cbr\u003E\nПрименение препарата Неванак у пациентов с заболеванием печени или почек не изучалось. Необходимость коррекции дозы для этой категории пациентов отсутствует, поскольку после применения местно, в виде инстилляций в конъюнктивальную полость его системная экспозиция очень невелика.\u003Cbr\u003E\nПациенты детского возраста (младше 18 лет)\u003Cbr\u003E\nБезопасность и эффективность применения препарата Неванак у детей и подростков не установлены. У пациентов этой возрастной группы не рекомендуется применять препарат Неванак до получения дополнительных данных.\u003Cbr\u003E\nПожилые пациенты (65 лет или старше)\u003Cbr\u003E\nНикаких различий в безопасности и эффективности у пожилых пациентов и пациентов более молодого возраста выявлено не было.\u003Cbr\u003E\nСпособ применения\u003Cbr\u003E\nМестно, в виде инстилляций в конъюнктивальную полость.\u003Cbr\u003E\nСледует сообщить пациенту о необходимости тщательно встряхивать флакон перед применением. После снятия крышки, если кольцо защиты от вскрытия не прилегает к горловине, его необходимо удалить перед применением препарата. В случае применения нескольких офтальмологических лекарственных препаратов их следует закапывать с интервалом не менее 5 минут. Мази для глаз следует наносить последними. Если доза препарата была пропущена, то 1 каплю следует закапать как можно скорее, перед возвратом к обычному режиму дозирования. Не следует компенсировать пропущенную дозу путем удваивания дозы. Не следует прикасаться кончиком флакона-капельницы к поверхностям, чтобы избежать контаминации. Также следует избегать контакта кончика флаконакапельницы с глазами, так как такой контакт может травмировать глаз. Необходимо предупредить пациента о необходимости хранить флакон плотно закрытым, когда он не используется."},{"name":"Побочные действия","value":"Местные. В 1-10 % случаев наблюдается точечный кератит, боль и зуд в глазу, неясность зрения, сухость конъюнктивы, ощущение инородного тела, образование корок на краях век. В 0,1-1 % случаев - ирит, кератит, отложения в роговице, хориоидальный выпот, выделения из глаз, фотофобия, раздражение глаз, аллергический конъюнктивит, нарушения со стороны век, дискомфорт в глазах, повышенное слезоотделение, гиперемия конъюнктивы.\u003Cbr\u003EСистемные побочные эффекты. В 1-10 % случаев - головная боль. В 1-4 % случаев - повышение артериального давления, тошнота, рвота, синусит. В 0,1-1 % случаев - сухость во рту, растяжимость кожи (дерматохалазис), гиперчувствительность\u003Cbr\u003EПостмаркетинговые наблюдения (частота неизвестна): язвенный кератит, дефект/заболевание эпителия роговицы, повреждение роговицы, образование воспалительного инфильтрата в передней камере глаза, ухудшение процесса заживления роговицы, снижение остроты зрения, рубец на роговице, помутнение роговицы.\u003Cbr\u003EПациентам с признаками повреждения роговицы следует немедленно отменить применение препарата и тщательно обследовать состояние роговицы!\u003Cbr\u003EОпыт применения нестероидных противовоспалительных препаратов для местного применения предполагает, что пациенты с осложнениями после хирургических офтальмологических вмешательств, денервацией роговицы, дефектами эпителия роговицы, сахарным диабетом, поверхностными заболеваниями глаз (например, синдром \"сухого глаза\"), ревматоидным артритом или повторными хирургическими вмешательствами, проведенными в течение короткого промежутка времени, могут иметь повышенный риск развития побочных реакций со стороны роговицы, что может создать угрозу потери зрения."},{"name":"Фармакологическое действие","value":"Непафенак - предшественник активной формы нестероидных противовоспалительных препаратов с противовоспалительным и анальгезирующим действием. При местном применении непафенак проникает через роговицу глаза, где при помощи гидролаз происходит его превращение в амфенак, активную форму. Амфенак ингибирует действие циклооксигеназы (простагландин-Н-синтазы), фермента, необходимого для продукции простагландинов. При местном применении непафенак уменьшает отек тканей глаза и боль, не оказывает значимого эффекта на внутриглазное давление."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"капли"},{"name":"Способ применения/введения","value":"конъюктивальный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["35947170:36763746"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить при температуре от 2 до 30 °С в недоступном для детей месте."},{"name":"Передозировка","value":"Данные по передозировке препарата отсутствуют.\u003Cbr\u003EПри попадании в глаза избыточного количества препарата рекомендуется промыть глаза теплой водой."},{"name":"Применение при беременности и кормлении грудью","value":"Не рекомендуется применение при беременности и лактации. При необходимости назначения в период лактации грудное вскармливание рекомендуется прекратить на время лечения.\u003Cbr\u003EИспытания на животных выявили репродуктивную токсичность. При исследовании воздействия непафенака на репродуктивные органы крыс, прием токсических доз \u003E10 мг/кг приводил к дистоции, увеличению количества самопроизвольных абортов на этапе после имплантации, снижению массы тела и роста эмбрионов, снижению выживаемости эмбрионов. У беременных крольчих прием малотоксичных доз 30 мг/кг приводил к увеличению пороков развития потомства."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"После применения препарата возможно временное снижение четкости зрительного восприятия, и до ее восстановления не рекомендуется управлять автомобилем и заниматься видами деятельности, требующими повышенного внимания и реакции."},{"name":"Особые указания","value":"Пациентам следует избегать воздействия солнечного света.\u003Cbr\u003EПрименение нестероидных противовоспалительных препаратов для местного применения может привести к развитию кератита. У некоторых восприимчивых пациентов длительное применение нестероидных противовоспалительных препаратов для местного применения может вызвать разрыв клеток эпителия, истончение роговицы, эрозию роговицы, образование язвы на роговице или перфорацию роговицы. Эти побочные явления могут создавать риск потери зрения. Пациенты с признаками разрыва клеток эпителия роговицы должны немедленно прекратить применение препарата, и находиться под наблюдением, целью которого является мониторинг состояния роговицы.\u003Cbr\u003EПрименение нестероидных противовоспалительных препаратов для местного применения может замедлять или задерживать процесс заживления. Также известно, что глюкокортикостероиды для местного применения замедляют или задерживают заживление. Одновременное применение нестероидных противовоспалительных препаратов для местного применения и глюкокортикостероидов для местного применения может замедлять или задерживать процесс заживления.\u003Cbr\u003EОпыт применения нестероидных противовоспалительных препаратов для местного применения предполагает, что пациенты с осложнениями после хирургических офтальмологических вмешательств, денервацией роговицы, дефектами эпителия роговицы, сахарным диабетом, поверхностными заболеваниями глаз (например, синдромом \"сухого глаза\"), ревматоидным артритом или повторными хирургическими вмешательствами, проведенными в течение короткого промежутка времени, могут иметь повышенный риск развития побочных реакций со стороны роговицы, что может создать угрозу потери зрения. Нестероидные противовоспалительные препараты для местного применения должны использоваться с осторожностью при лечении таких пациентов. Длительное применение может увеличить риск возникновения и степень тяжести побочных реакций со стороны роговицы.\u003Cbr\u003EПрименение нестероидных противовоспалительных препаратов для местного применения в сочетании с хирургической операцией на глазах могут вызывать интенсивное кровотечение в тканях глаза (включая гифему). Препарат Неванак должен использоваться с осторожностью у пациентов, в анамнезе которых зафиксирована склонность к кровотечению, или если пациенты получают другие лекарственные препараты, которые могут повышать время свертываемости крови.\u003Cbr\u003EДанные по одновременному применению аналогов простагландина и препарата Неванак отсутствуют. Учитывая механизмы их действия, одновременное применение не рекомендуется.\u003Cbr\u003EПрепарат содержит консервант бензалкония хлорид, который может вызывать раздражение глаз и обесцвечивание мягких контактных линз. Кроме того, ношение контактных линз не рекомендуется во время послеоперационного периода после хирургической операции по поводу катаракты. Не рекомендуется использовать контактные линзы при лечении препаратом Неванак.\u003Cbr\u003EИсследования показали, что бензалкония хлорид, который содержится в препарате Неванак, может вызывать точечный кератит и/или токсичный язвенный кератит. Поэтому при частом или длительном использовании препарата необходимо тщательное медицинское наблюдение за состоянием пациентов.\u003Cbr\u003EПрименение нестероидных противовоспалительных препаратов для местного применения может препятствовать своевременному распознаванию признаков острой глазной инфекции, т.к. они не обладают какими-либо противомикробными свойствами. В случае развития глазной инфекции, применение нестероидных противовоспалительных препаратов для местного применения одновременно с антибактериальными средствами должно осуществляться с соблюдением мер предосторожности.\u003Cbr\u003EПерекрестная чувствительность\u003Cbr\u003EПри применении непафенака существует возможность развития перекрестной чувствительности к ацетилсалициловой кислоте, производным фенилуксусной кислоты, а также другим нестероидным противовоспалительным препаратам!\u003Cbr\u003EНе следует прикасаться кончиком флакона-капельницы к какой-либо поверхности, чтобы избежать загрязнения флакона и его содержимого.\u003Cbr\u003EФлакон необходимо закрывать после каждого использования."},{"name":"Взаимодействие","value":"В исследованиях in vitro ни непафенак, ни амфенак не ингибируют метаболическую активность человеческого цитохрома Р450 (изофермент CYP1A2, 2С9, 2С19, 2D6, 2Е1 и ЗА4) при концентрации до 300 нг/мл. Следовательно, при одновременном применении с другими лекарственными препаратами взаимодействие с вовлечением изоферментов цитохрома Р450 маловероятно. Также маловероятны взаимодействия, опосредованные связыванием с белками плазмы.\u003Cbr\u003EДанные по одновременному применению препарата Неванак и аналогов простагландина отсутствуют. Учитывая механизмы их действия, одновременное применение не рекомендуется.\u003Cbr\u003EПри необходимости может применяться в комбинации с другими офтальмологическими препаратами для местного применения. В этом случае интервал между их применением должен составлять не менее 5 минут."},{"name":"Источник","value":"\u003Ca href=\"https://www.vidal.ru\" target=\"_blank\"\u003EСправочник лекарственных препаратов Видаль<\u002Fa\u003E"},{"name":"Регистрационный номер","value":"ЛП-001118"},{"name":"Дата государственной регистрации","value":"20.04.2017"},{"name":"Владелец регистрационного удостоверения","value":"Novartis","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["34324371:35649313","7893318:11037328"]}}},{"name":"Изготовитель","value":"S.A. Alcon-Couvreur N.V."},{"name":"Фасовщик","value":"S.A. Alcon-Couvreur N.V."},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Бельгия"},{"name":"Название препарата","value":"Неванак","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["17796364:18044923"]}}},{"name":"Срок годности","value":"23 мес."}]}},"fullSpecsGrouped":{"17935713076245592939":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"глаза"},{"name":"Назначение","value":"профилактика и лечение боли и воспаления в послеоперационном периоде экстракции катаракты"},{"name":"Показания к применению","value":"Профилактика и лечение послеоперационной боли и воспалительных явлений при хирургических вмешательствах по поводу удаления катаракты."},{"name":"Противопоказания","value":"Индивидуальная гиперчувствительность к компонентам препарата, а также к другим нестероидным противовоспалительным препаратам.\u003Cbr\u003EБронхиальная астма, крапивница, острый ринит, вызванные приемом ацетилсалициловой кислоты или других нестероидных противовоспалительных препаратов.\u003Cbr\u003EВозраст до 18 лет (безопасность и эффективность применения препарата у детей не исследовались)."},{"name":"Состав","value":"Состав 1 мл препарата.\u003Cbr\u003EАктивное вещество: непафенак 1,0 мг.\u003Cbr\u003EВспомогательные вещества: бензалкония хлорид (в виде 50 % раствора) 0,05 мг; карбомер (974Р) 5,0 мг; тилоксапол 0,1 мг; динатрия эдетат 0,1 мг; маннитол 24,0 мг; натрия хлорид 4,0 мг; натрия гидроксид и/или кислота хлористоводородная до доведения pH, вода очищенная до 1 мл."},{"name":"Действующее вещество","value":"Непафенак"},{"name":"Способ применения и дозы","value":"Взрослые, включая пациентов пожилого возраста\u003Cbr\u003E\nПрофилактика и лечение боли и воспаления в послеоперационном периоде экстракции катаракты\u003Cbr\u003E\nПо 1 капле препарата Неванак в конъюнктивальный мешок глаза (глаз) 3 раза в сутки, Лечение начинают за день до хирургического вмешательства по удалению катаракты и продолжают в течение первых 2 недель послеоперационного периода (включая день операции).\u003Cbr\u003E\nЗа 30-120 минут до операции необходимо закапать дополнительную каплю препарата.\u003Cbr\u003E\nЛечение может быть продлено до 3 недель послеоперационного периода по назначению врача.\u003Cbr\u003E\nСнижение риска развития макулярного отека у пациентов с сахарным диабетом в послеоперационном периоде экстракции катаракты\u003Cbr\u003E\nПо 1 капле препарата Неванак в конъюнктивальный мешок глаза (глаз) 3 раза в сутки. Лечение начинают за 1 день до хирургического вмешательства по удалению катаракты, затем продолжают в день операции и в послеоперационный период продолжительностью до 60 дней по назначению врача.\u003Cbr\u003E\nЗа 30-120 минут до операции необходимо закапать дополнительную каплю препарата.\u003Cbr\u003E\nОсобые группы пациентов\u003Cbr\u003E\nПациенты с нарушением функции печени и почек\u003Cbr\u003E\nПрименение препарата Неванак у пациентов с заболеванием печени или почек не изучалось. Необходимость коррекции дозы для этой категории пациентов отсутствует, поскольку после применения местно, в виде инстилляций в конъюнктивальную полость его системная экспозиция очень невелика.\u003Cbr\u003E\nПациенты детского возраста (младше 18 лет)\u003Cbr\u003E\nБезопасность и эффективность применения препарата Неванак у детей и подростков не установлены. У пациентов этой возрастной группы не рекомендуется применять препарат Неванак до получения дополнительных данных.\u003Cbr\u003E\nПожилые пациенты (65 лет или старше)\u003Cbr\u003E\nНикаких различий в безопасности и эффективности у пожилых пациентов и пациентов более молодого возраста выявлено не было.\u003Cbr\u003E\nСпособ применения\u003Cbr\u003E\nМестно, в виде инстилляций в конъюнктивальную полость.\u003Cbr\u003E\nСледует сообщить пациенту о необходимости тщательно встряхивать флакон перед применением. После снятия крышки, если кольцо защиты от вскрытия не прилегает к горловине, его необходимо удалить перед применением препарата. В случае применения нескольких офтальмологических лекарственных препаратов их следует закапывать с интервалом не менее 5 минут. Мази для глаз следует наносить последними. Если доза препарата была пропущена, то 1 каплю следует закапать как можно скорее, перед возвратом к обычному режиму дозирования. Не следует компенсировать пропущенную дозу путем удваивания дозы. Не следует прикасаться кончиком флакона-капельницы к поверхностям, чтобы избежать контаминации. Также следует избегать контакта кончика флаконакапельницы с глазами, так как такой контакт может травмировать глаз. Необходимо предупредить пациента о необходимости хранить флакон плотно закрытым, когда он не используется."},{"name":"Побочные действия","value":"Местные. В 1-10 % случаев наблюдается точечный кератит, боль и зуд в глазу, неясность зрения, сухость конъюнктивы, ощущение инородного тела, образование корок на краях век. В 0,1-1 % случаев - ирит, кератит, отложения в роговице, хориоидальный выпот, выделения из глаз, фотофобия, раздражение глаз, аллергический конъюнктивит, нарушения со стороны век, дискомфорт в глазах, повышенное слезоотделение, гиперемия конъюнктивы.\u003Cbr\u003EСистемные побочные эффекты. В 1-10 % случаев - головная боль. В 1-4 % случаев - повышение артериального давления, тошнота, рвота, синусит. В 0,1-1 % случаев - сухость во рту, растяжимость кожи (дерматохалазис), гиперчувствительность\u003Cbr\u003EПостмаркетинговые наблюдения (частота неизвестна): язвенный кератит, дефект/заболевание эпителия роговицы, повреждение роговицы, образование воспалительного инфильтрата в передней камере глаза, ухудшение процесса заживления роговицы, снижение остроты зрения, рубец на роговице, помутнение роговицы.\u003Cbr\u003EПациентам с признаками повреждения роговицы следует немедленно отменить применение препарата и тщательно обследовать состояние роговицы!\u003Cbr\u003EОпыт применения нестероидных противовоспалительных препаратов для местного применения предполагает, что пациенты с осложнениями после хирургических офтальмологических вмешательств, денервацией роговицы, дефектами эпителия роговицы, сахарным диабетом, поверхностными заболеваниями глаз (например, синдром \"сухого глаза\"), ревматоидным артритом или повторными хирургическими вмешательствами, проведенными в течение короткого промежутка времени, могут иметь повышенный риск развития побочных реакций со стороны роговицы, что может создать угрозу потери зрения."},{"name":"Фармакологическое действие","value":"Непафенак - предшественник активной формы нестероидных противовоспалительных препаратов с противовоспалительным и анальгезирующим действием. При местном применении непафенак проникает через роговицу глаза, где при помощи гидролаз происходит его превращение в амфенак, активную форму. Амфенак ингибирует действие циклооксигеназы (простагландин-Н-синтазы), фермента, необходимого для продукции простагландинов. При местном применении непафенак уменьшает отек тканей глаза и боль, не оказывает значимого эффекта на внутриглазное давление."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"капли"},{"name":"Способ применения/введения","value":"конъюктивальный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре от 2 до 30 °С в недоступном для детей месте."},{"name":"Передозировка","value":"Данные по передозировке препарата отсутствуют.\u003Cbr\u003EПри попадании в глаза избыточного количества препарата рекомендуется промыть глаза теплой водой."},{"name":"Применение при беременности и кормлении грудью","value":"Не рекомендуется применение при беременности и лактации. При необходимости назначения в период лактации грудное вскармливание рекомендуется прекратить на время лечения.\u003Cbr\u003EИспытания на животных выявили репродуктивную токсичность. При исследовании воздействия непафенака на репродуктивные органы крыс, прием токсических доз \u003E10 мг/кг приводил к дистоции, увеличению количества самопроизвольных абортов на этапе после имплантации, снижению массы тела и роста эмбрионов, снижению выживаемости эмбрионов. У беременных крольчих прием малотоксичных доз 30 мг/кг приводил к увеличению пороков развития потомства."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"После применения препарата возможно временное снижение четкости зрительного восприятия, и до ее восстановления не рекомендуется управлять автомобилем и заниматься видами деятельности, требующими повышенного внимания и реакции."},{"name":"Особые указания","value":"Пациентам следует избегать воздействия солнечного света.\u003Cbr\u003EПрименение нестероидных противовоспалительных препаратов для местного применения может привести к развитию кератита. У некоторых восприимчивых пациентов длительное применение нестероидных противовоспалительных препаратов для местного применения может вызвать разрыв клеток эпителия, истончение роговицы, эрозию роговицы, образование язвы на роговице или перфорацию роговицы. Эти побочные явления могут создавать риск потери зрения. Пациенты с признаками разрыва клеток эпителия роговицы должны немедленно прекратить применение препарата, и находиться под наблюдением, целью которого является мониторинг состояния роговицы.\u003Cbr\u003EПрименение нестероидных противовоспалительных препаратов для местного применения может замедлять или задерживать процесс заживления. Также известно, что глюкокортикостероиды для местного применения замедляют или задерживают заживление. Одновременное применение нестероидных противовоспалительных препаратов для местного применения и глюкокортикостероидов для местного применения может замедлять или задерживать процесс заживления.\u003Cbr\u003EОпыт применения нестероидных противовоспалительных препаратов для местного применения предполагает, что пациенты с осложнениями после хирургических офтальмологических вмешательств, денервацией роговицы, дефектами эпителия роговицы, сахарным диабетом, поверхностными заболеваниями глаз (например, синдромом \"сухого глаза\"), ревматоидным артритом или повторными хирургическими вмешательствами, проведенными в течение короткого промежутка времени, могут иметь повышенный риск развития побочных реакций со стороны роговицы, что может создать угрозу потери зрения. Нестероидные противовоспалительные препараты для местного применения должны использоваться с осторожностью при лечении таких пациентов. Длительное применение может увеличить риск возникновения и степень тяжести побочных реакций со стороны роговицы.\u003Cbr\u003EПрименение нестероидных противовоспалительных препаратов для местного применения в сочетании с хирургической операцией на глазах могут вызывать интенсивное кровотечение в тканях глаза (включая гифему). Препарат Неванак должен использоваться с осторожностью у пациентов, в анамнезе которых зафиксирована склонность к кровотечению, или если пациенты получают другие лекарственные препараты, которые могут повышать время свертываемости крови.\u003Cbr\u003EДанные по одновременному применению аналогов простагландина и препарата Неванак отсутствуют. Учитывая механизмы их действия, одновременное применение не рекомендуется.\u003Cbr\u003EПрепарат содержит консервант бензалкония хлорид, который может вызывать раздражение глаз и обесцвечивание мягких контактных линз. Кроме того, ношение контактных линз не рекомендуется во время послеоперационного периода после хирургической операции по поводу катаракты. Не рекомендуется использовать контактные линзы при лечении препаратом Неванак.\u003Cbr\u003EИсследования показали, что бензалкония хлорид, который содержится в препарате Неванак, может вызывать точечный кератит и/или токсичный язвенный кератит. Поэтому при частом или длительном использовании препарата необходимо тщательное медицинское наблюдение за состоянием пациентов.\u003Cbr\u003EПрименение нестероидных противовоспалительных препаратов для местного применения может препятствовать своевременному распознаванию признаков острой глазной инфекции, т.к. они не обладают какими-либо противомикробными свойствами. В случае развития глазной инфекции, применение нестероидных противовоспалительных препаратов для местного применения одновременно с антибактериальными средствами должно осуществляться с соблюдением мер предосторожности.\u003Cbr\u003EПерекрестная чувствительность\u003Cbr\u003EПри применении непафенака существует возможность развития перекрестной чувствительности к ацетилсалициловой кислоте, производным фенилуксусной кислоты, а также другим нестероидным противовоспалительным препаратам!\u003Cbr\u003EНе следует прикасаться кончиком флакона-капельницы к какой-либо поверхности, чтобы избежать загрязнения флакона и его содержимого.\u003Cbr\u003EФлакон необходимо закрывать после каждого использования."},{"name":"Взаимодействие","value":"В исследованиях in vitro ни непафенак, ни амфенак не ингибируют метаболическую активность человеческого цитохрома Р450 (изофермент CYP1A2, 2С9, 2С19, 2D6, 2Е1 и ЗА4) при концентрации до 300 нг/мл. Следовательно, при одновременном применении с другими лекарственными препаратами взаимодействие с вовлечением изоферментов цитохрома Р450 маловероятно. Также маловероятны взаимодействия, опосредованные связыванием с белками плазмы.\u003Cbr\u003EДанные по одновременному применению препарата Неванак и аналогов простагландина отсутствуют. Учитывая механизмы их действия, одновременное применение не рекомендуется.\u003Cbr\u003EПри необходимости может применяться в комбинации с другими офтальмологическими препаратами для местного применения. В этом случае интервал между их применением должен составлять не менее 5 минут."},{"name":"Источник","value":"\u003Ca href=\"https://www.vidal.ru\" target=\"_blank\"\u003EСправочник лекарственных препаратов Видаль<\u002Fa\u003E"},{"name":"Регистрационный номер","value":"ЛП-001118"},{"name":"Дата государственной регистрации","value":"20.04.2017"},{"name":"Владелец регистрационного удостоверения","value":"Novartis"},{"name":"Изготовитель","value":"S.A. Alcon-Couvreur N.V."},{"name":"Фасовщик","value":"S.A. Alcon-Couvreur N.V."},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Бельгия"},{"name":"Название препарата","value":"Неванак"},{"name":"Срок годности","value":"23 мес."}]}],"transitionId":"tr_13614118296705816324"}}}}
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Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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1 003 ₽

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ЕАПТЕКА
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    –17 %
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    Хило-комод р-р увлажняющий офтальмологический конт., 1 мг/мл, 10 мл, 2 шт., 2 уп.

    Рейтинг товара: 4.9 из 5
    на основе 34 оценки
    Цена 2 290 ₽ вместо 2 748
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  • Тобрадекс гл. капли, 5 мл
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    Тобрадекс гл. капли, 5 мл

    Рейтинг товара: 5 из 5
    на основе 14 оценок
    Цена 666 ₽
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  • Корнерегель гл. гель, 5%, 5 г
    –1 %
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    Корнерегель гл. гель, 5%, 5 г

    Рейтинг товара: 4.8 из 5
    на основе 72 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 590 ₽ вместо 596
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  • НЕПАФЕНАК-ОПТИК гл. капли фл.-кап., 1 мг/мл, 5 мл
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    НЕПАФЕНАК-ОПТИК гл. капли фл.-кап., 1 мг/мл, 5 мл

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 585 ₽
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  • Броксинак гл. капли, 0.09%, 2.5 мл
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    Броксинак гл. капли, 0.09%, 2.5 мл

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 836 ₽
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  • Isotine гл. капли фл.-капельница, 10 мл, 10 мл, 20 г, 1 шт.
    –22 %
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    Isotine гл. капли фл.-капельница, 10 мл, 10 мл, 20 г, 1 шт.

    Рейтинг товара: 4.6 из 5
    на основе 113 оценок
    Цена 305 ₽ вместо 390
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  • Тобрекс гл. капли, 0.3%, 5 мл
    –15 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9ieptpo0aya/toggleWishlist":{"skuId":"228067856","productId":1778174381,"offerId":"hAzwvvoXfrAuDBRIL6eUhw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9t2r8ISdpPFeEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIrZPzzwYQkJTgbBiQ1aEFINzcwQc=","sign":"JHlYTPKU5Jpk7Okr0rnnn96HKzGyaj6dpMZlx3wyV44="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9ieptpo0aya/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тобрекс гл. капли, 0.3%, 5 мл

    Рейтинг товара: 5 из 5
    на основе 17 оценок
    Цена 138 ₽ вместо 163
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  • Ирифрин гл. капли, 2,5%, 5 мл, 1 шт.
    –17 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ubjlmn3a9s/toggleWishlist":{"skuId":"265318686","productId":1778174600,"offerId":"gIt5PRwYKUeDxUTSyYRN7A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9t2r8ISdpPFeEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIiJXzzwYQnuLBfhjovt4HINzcwQc=","sign":"ysbO6iJzGvtTreHwe9CkEwUYBzpVpfoS/tMiORbV5ps="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ubjlmn3a9s/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ирифрин гл. капли, 2,5%, 5 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 11 оценок
    Цена 769 ₽ вместо 930
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  • Дексаметазон гл. капли фл.-капельница, 0.1%, 10 мл
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    Дексаметазон гл. капли фл.-капельница, 0.1%, 10 мл

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 347 ₽
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  • Азопт гл. капли, 1%, 5 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-bnvuspkpj9g/toggleWishlist":{"skuId":"226182682","productId":1778174316,"offerId":"P87GrUJGfd7gG62A_U9zIw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9t2r8ISdpPFeEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI7JLzzwYQmoztaxiQ1aEFINzcwQc=","sign":"xEwC5/E3LliMiipzWyY4/VKYQCcuOV2EnwluFXn4NaI="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-bnvuspkpj9g/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Азопт гл. капли, 1%, 5 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 1 199 ₽
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  • Накван гл. капли фл., 0.09%, 5 мл
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    Накван гл. капли фл., 0.09%, 5 мл

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 673 ₽
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  • Макситрол гл. капли фл.-капельница, 1 мг/мл, 5 мл
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dktyu6102x4/toggleWishlist":{"skuId":"228047655","productId":1778174363,"offerId":"NbamolQhUmPOQZr1v3qbfA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ9t2r8ISdpPFeEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIm5PzzwYQp/bebBiQ1aEFINzcwQc=","sign":"cj6Dossggsfpfs5GwBA2x2yicPTtciw6Nvx2E7X8vy8="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dktyu6102x4/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Макситрол гл. капли фл.-капельница, 1 мг/мл, 5 мл

    Рейтинг товара: 5 из 5
    на основе 5 оценок
    Цена 774 ₽
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Инструкция

Показания к применению

Профилактика и лечение послеоперационной боли и воспалительных явлений при хирургических вмешательствах по поводу удаления катаракты.

Противопоказания

Индивидуальная гиперчувствительность к компонентам препарата, а также к другим нестероидным противовоспалительным препаратам.
Бронхиальная астма, крапивница, острый ринит, вызванные приемом ацетилсалициловой кислоты или других нестероидных противовоспалительных препаратов.
Возраст до 18 лет (безопасность и эффективность применения препарата у детей не исследовались).

Способ применения и дозы

Взрослые, включая пациентов пожилого возраста
Профилактика и лечение боли и воспаления в послеоперационном периоде экстракции катаракты
По 1 капле препарата Неванак в конъюнктивальный мешок глаза (глаз) 3 раза в сутки, Лечение начинают за день до хирургического вмешательства по удалению катаракты и продолжают в течение первых 2 недель послеоперационного периода (включая день операции).
За 30-120 минут до операции необходимо закапать дополнительную каплю препарата.
Лечение может быть продлено до 3 недель послеоперационного периода по назначению врача.
Снижение риска развития макулярного отека у пациентов с сахарным диабетом в послеоперационном периоде экстракции катаракты
По 1 капле препарата Неванак в конъюнктивальный мешок глаза (глаз) 3 раза в сутки. Лечение начинают за 1 день до хирургического вмешательства по удалению катаракты, затем продолжают в день операции и в послеоперационный период продолжительностью до 60 дней по назначению врача.
За 30-120 минут до операции необходимо закапать дополнительную каплю препарата.
Особые группы пациентов
Пациенты с нарушением функции печени и почек
Применение препарата Неванак у пациентов с заболеванием печени или почек не изучалось. Необходимость коррекции дозы для этой категории пациентов отсутствует, поскольку после применения местно, в виде инстилляций в конъюнктивальную полость его системная экспозиция очень невелика.
Пациенты детского возраста (младше 18 лет)
Безопасность и эффективность применения препарата Неванак у детей и подростков не установлены. У пациентов этой возрастной группы не рекомендуется применять препарат Неванак до получения дополнительных данных.
Пожилые пациенты (65 лет или старше)
Никаких различий в безопасности и эффективности у пожилых пациентов и пациентов более молодого возраста выявлено не было.
Способ применения
Местно, в виде инстилляций в конъюнктивальную полость.
Следует сообщить пациенту о необходимости тщательно встряхивать флакон перед применением. После снятия крышки, если кольцо защиты от вскрытия не прилегает к горловине, его необходимо удалить перед применением препарата. В случае применения нескольких офтальмологических лекарственных препаратов их следует закапывать с интервалом не менее 5 минут. Мази для глаз следует наносить последними. Если доза препарата была пропущена, то 1 каплю следует закапать как можно скорее, перед возвратом к обычному режиму дозирования. Не следует компенсировать пропущенную дозу путем удваивания дозы. Не следует прикасаться кончиком флакона-капельницы к поверхностям, чтобы избежать контаминации. Также следует избегать контакта кончика флаконакапельницы с глазами, так как такой контакт может травмировать глаз. Необходимо предупредить пациента о необходимости хранить флакон плотно закрытым, когда он не используется.
Полная инструкция
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Неванак гл. капли фл.-капельница
Неванак гл. капли фл.-капельница, 0.1%, 5 мл
4.7
(9)
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3 вопроса
Инструкция

1 003 ₽

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4.7
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У продавца:9 оценок·1 отзыв
У всех продавцов:73 оценки·11 отзывов
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7 месяцев назад • Юрий Брыкин • Куплен на Маркете
Достоинства: то ,что доктор прописал
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