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Орлистат-Акрихин капс., 60 мг, 42 шт.

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4.6
(73)
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Коротко о товаре

Артикул Маркета
34691350
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Если прием пищи пропускают или пища не содержит жира, прием орлистата также можно пропустить.\u003Cbr\u003EВ течение 24 часов не следует принимать более 3 капсул по 60 мг.\u003Cbr\u003EЕсли через 12 недель терапии не произошло снижения массы тела, прием орлистата следует прекратить. Лечение не должно превышать 6 месяцев.\u003Cbr\u003EУ пожилых пациентов, пациентов с нарушениями функции печени и почек коррекции дозы не требуется.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EПациенты пожилого возраста (\u003E 65 лет)\u003Cbr\u003EЕсть ограниченные данные о применении орлистата у лиц пожилого возраста. 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Действует в просвете желудка и тонкого кишечника, образуя ковалентную связь с активным сериновым участком желудочной и панкреатической липаз. Инактивированный фермент не способен расщеплять жиры пищи, поступающие в виде триглицеридов, до абсорбируемых свободных жирных кислот и моноглицеридов. Нерасщепленные триглицериды не всасываются, в связи с чем, уменьшается поступление калорий в организм, что приводит к уменьшению массы тела. Терапевтическое действие препарата осуществляется без всасывания в системный кровоток. Увеличивает концентрацию жира в каловых массах через 24-48 ч после приема. Обеспечивает эффективный контроль массы тела, уменьшение доли жира.\u003Cbr\u003EУ взрослых людей с индексом массы тела (ИМТ) \u003E 28 кг/м2 орлистат в дозе 60 мг три раза в день эффективен в сочетании с гипокалорийной диетой с низким содержанием жиров. При этом, основная потеря массы тела происходит в течение первых 6 месяцев лечения. Снижение массы тела, обусловленное применением орлистата в дозе 60 мг три раза в день, сопровождается и другим благоприятным действием: снижением концентрации общего холестерина, холестерина ЛПНП, а также уменьшением окружности талии."},{"name":"Фармакологическая группа","value":"ингибиторы липазы ЖКТ"},{"name":"Форма выпуска","value":"капсулы"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °C, в оригинальной упаковке.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"У лиц с нормальной массой тела и ожирением прием однократных доз орлистата (800 мг) и многократных (до 400 мг орлистата 3 раза в день на протяжении 15 дней) не вызывал нежелательных явлений. Кроме того, у пациентов с ожирением прием орлистата в дозе 240 мг 3 раза в день на протяжении 6 месяцев не сопровождался усилением нежелательных явлений.\u003Cbr\u003EВ большинстве сообщений о случаях передозировки орлистата говорилось об отсутствии нежелательных реакций, либо нежелательные реакции были подобны тем, которые наблюдались при применении орлистата в рекомендуемых дозах.\u003Cbr\u003EВ случае значительной передозировки орлистата рекомендуется наблюдение пациента на протяжении 24 часов. По данным доклинических и клинических исследований, системные эффекты, связанные с липазингибирующими свойствами орлистата, должны быть быстро обратимыми."},{"name":"Применение при беременности и кормлении грудью","value":"Доклинические исследования не выявили тератогенного и эмбриотоксического эффекта орлистата. Однако, в связи с отсутствием клинических данных о применении у беременных, орлистат противопоказан при беременности.\u003Cbr\u003EПоскольку неизвестно, проникает ли орлистат в грудное молоко, он противопоказан в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Не выявлено какого-либо отрицательного влияния орлистата на способность управлять автотранспортными средствами и механизмами."},{"name":"Особые указания","value":"Диета и физические упражнения являются неотъемлемой частью программы снижения массы тела. Рекомендуется начинать диетическую программу и физические упражнения до начала терапии препаратом Орлистат-Акрихин.\u003Cbr\u003EВо время приема препарата Орлистат-Акрихин необходимо придерживаться дробного, сбалансированного, умеренно гипокалорийного питания, с содержанием жира не более 30% от суточной калорийности рациона (например, при рационе 2000 ккал/день\u003Cbr\u003Eпотребление жира должно составлять не более 66 г/день). Следует придерживаться полученных рекомендаций по режиму питания и физической активности, как во время, так и после прекращения приема препарата.\u003Cbr\u003EПрименение препарата Орлистат-Акрихин приводит к увеличению содержания жира в кале уже спустя 24-48 часов после начала приема. После прекращения применения препарата Орлистат-Акрихин содержание жира в кале обычно возвращается к исходному уровню в течение 48-72 часов.\u003Cbr\u003EСоблюдение диеты с низким содержанием жира уменьшает вероятность возникновения нежелательных реакций со стороны ЖКТ.\u003Cbr\u003EПрием орлистата потенциально может ухудшать всасывание жирорастворимых витаминов (A, D, E, K и бета-каротин). У подавляющего большинства пациентов, получавших орлистат в ходе четырехлетних клинических исследований, концентрация витаминов A, D, E, K и бета-каротина были в пределах нормальных значений. С профилактической целью рекомендуется принимать поливитамины на ночь.\u003Cbr\u003EПоскольку потеря массы тела обычно сопровождается улучшением показателей углеводного обмена, пациенты с сахарным диабетом 2 типа перед началом терапии препаратом Орлистат-Акрихин должны проконсультироваться с врачом и, в случае необходимости, скорректировать дозу гипогликемических препаратов.\u003Cbr\u003EСнижение массы тела при лечении может сопровождаться снижением артериального давления и концентрации ОХс в плазме крови. Пациентам, принимающим гипотензивные или гиполипидемические препараты, следует проконсультироваться с врачом и, в случае необходимости, провести коррекцию дозы этих лекарственных препаратов.\u003Cbr\u003EВ клинических исследованиях взаимодействия между контрацептивами для приема внутрь и орлистатом не наблюдалось. Однако орлистат может опосредованно снижать биодоступность контрацептивов для приема внутрь, что может привести к развитию нежелательной беременности. Рекомендуется применять дополнительные методы контрацепции в случае развития острой диареи.\u003Cbr\u003EПациентам с заболеванием почек необходимо проконсультироваться с врачом, так как возможно развитие гипероксалурии и нефропатии.\u003Cbr\u003EПациентам, принимающим амиодарон, варфарин или другие антикоагулянты для приема внутрь, также следует проконсультироваться с врачом до начала терапии орлистатом, поскольку возможны изменения показателя МНО.\u003Cbr\u003EПациентам следует прекратить прием препарата Орлистат-Акрихин и обратиться к врачу в случае появления симптомов: желтушное окрашивание склеры или кожи, кожный зуд, потемнение мочи и потеря аппетита.\u003Cbr\u003EПри применении орлистата наблюдались случаи ректального кровотечения. Если возникает это явление пациент должен проконсультироваться с врачом.\u003Cbr\u003EПри совместном применении орлистата и левотироксина натрия может развиться гипотиреоз и/или снижение контроля гипотиреоза. Пациентам, принимающим левотироксин натрия, следует проконсультироваться с врачом перед началом лечения орлистатом, т.к. может возникнуть необходимость в приеме орлистата и левотироксина натрия в разное время, а также, возможно, потребуется коррекция дозы левотироксина натрия.\u003Cbr\u003EПациентам, принимающим противоэпилептические препараты, следует проконсультироваться с врачом перед началом лечения орлистатом, т.к. они должны находиться под наблюдением в отношении возможных изменений частоты возникновения и степени выраженности судорог. В этих случаях следует рассмотреть возможность приема орлистата и противоэпилептических препаратов в разное время.\u003Cbr\u003EПациенты должны проконсультироваться с врачом перед началом применения орлистата одновременно с антиретровирусными препаратами, применяемыми для лечения ВИЧ-инфекции. Орлистат-Акрихин может уменьшать всасывание антиретровирусных препаратов и негативно влиять на их эффективность."},{"name":"Взаимодействие","value":"При одновременном применении орлистата и циклоспорина возможно снижение концентрации циклоспорина в плазме крови, в связи с чем необходимо мониторировать содержание циклоспорина в плазме крови. Одновременное применение орлистата и циклоспорина противопоказано.\u003Cbr\u003EПри одновременном применении орлистата с амиодароном рекомендуется клиническое наблюдение и мониторинг ЭКГ, так как возможно снижение концентрации амиодарона в плазме крови.\u003Cbr\u003EПри одновременном приеме орлистата и варфарина или других антикоагулянтов, может наблюдаться снижение концентрации протромбина и повышение МНО, что приводит к изменению гемостатических показателей. Одновременное применение орлистата и варфарина и других пероральных антикоагулянтов противопоказано.\u003Cbr\u003EОрлистат может уменьшать абсорбцию жирорастворимых витаминов A, D, Е, К и бета- каротина. Если показан прием поливитаминов, то их следует принимать не ранее, чем через 2 часа после приема орлистата или перед сном.\u003Cbr\u003EОрлистат может снижать всасывание противоэпилептических препаратов, что может привести к возникновению судорог.\u003Cbr\u003EС учетом отсутствия исследований фармакокинетического взаимодействия, совместного назначения орлистата и акарбозы необходимо избегать.\u003Cbr\u003EВ отдельных случаях орлистат может непрямым путем снижать биодоступность пероральных контрацептивов. В случае тяжелой диареи рекомендуется применение дополнительного метода контрацепции.\u003Cbr\u003EПри одновременном приеме с левотироксином натрия, в связи с уменьшением всасывания неорганического йода и/или левотироксина натрия, может развиться гипотиреоз и/или снижение контроля гипотиреоза.\u003Cbr\u003EНе выявлено лекарственного взаимодействия с амитриптилином, аторвастатином, бигуанидами, дигоксином, фибратами, флуоксетином, лозартаном, фенитоином, фентермином, правастатином, нифедипином, сибутрамином и этанолом."},{"name":"Регистрационный номер","value":"ЛП-002322"},{"name":"Дата государственной регистрации","value":"08.10.2019"},{"name":"Владелец регистрационного удостоверения","value":"Polpharma","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:16002745"]}}},{"name":"Изготовитель","value":"Polpharma"},{"name":"Страна бренда","value":"Польша"},{"name":"Страна-производитель","value":"Польша"},{"name":"Название препарата","value":"Орлистат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["17796364:18014575"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"13583737306437187668":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"пищеварительная система"},{"name":"Назначение","value":"избыточная масса тела, похудение"},{"name":"Показания к применению","value":"Снижение избыточной массы тела (ИМТ \u003E28 кг/м2) при применении в сочетании с умеренно гипокалорийной диетой с низким содержанием жиров."},{"name":"Противопоказания","value":"- Повышенная чувствительность к любому из компонентов препарата;\u003Cbr\u003E- Синдром хронической мальабсорбции;\u003Cbr\u003E- Холестаз;\u003Cbr\u003E- Сопутствующая терапия варфарином или другими пероральными антикоагулянтами;\u003Cbr\u003E- Сопутствующая терапия циклоспорином;\u003Cbr\u003E- Период беременности и лактации;\u003Cbr\u003E- Детский возраст до 18 лет."},{"name":"Состав","value":"На 1 капсулу (мг):\u003Cbr\u003Eактивное вещество: орлистат - 60,00;\u003Cbr\u003Eвспомогательные вещества: целлюлоза микрокристаллическая - 28,55;\u003Cbr\u003Eкарбоксиметилкрахмал натрия - 20,75; кремния диоксид коллоидный - 4,55; натрия лаурилсульфат -1,15;\u003Cbr\u003Eоболочка капсулы: твердая желатиновая капсула № 3 (желатин - 47,01; титана диоксид (Е171) - 0,96; индигокармин (Е132) - 0,03)."},{"name":"Действующее вещество","value":"Орлистат"},{"name":"Способ применения и дозы","value":"Внутрь, запивая водой, в рекомендуемой дозе 60 мг перед каждым основным приемом пищи, вместе с пищей или не позднее, чем через час после приема пищи. Если прием пищи пропускают или пища не содержит жира, прием орлистата также можно пропустить.\u003Cbr\u003EВ течение 24 часов не следует принимать более 3 капсул по 60 мг.\u003Cbr\u003EЕсли через 12 недель терапии не произошло снижения массы тела, прием орлистата следует прекратить. Лечение не должно превышать 6 месяцев.\u003Cbr\u003EУ пожилых пациентов, пациентов с нарушениями функции печени и почек коррекции дозы не требуется.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EПациенты пожилого возраста (\u003E 65 лет)\u003Cbr\u003EЕсть ограниченные данные о применении орлистата у лиц пожилого возраста. Однако, учитывая, что всасывание орлистата минимально, коррекции дозы у данной группы пациентов не требуется.\u003Cbr\u003EПациенты с печеночной и почечной недостаточностью\u003Cbr\u003EДействие орлистата у лиц с печеночной и/или почечной недостаточностью не изучалось.\u003Cbr\u003EОднако, учитывая, что всасывание орлистата минимально, коррекции дозы у пациентов с печеночной и/или почечной недостаточностью не требуется.\u003Cbr\u003EДети\u003Cbr\u003EПрименение орлистата 60 мг противопоказано у детей в возрасте до 18 лет из-за недостаточности данных о безопасности и эффективности."},{"name":"Побочные действия","value":"Нежелательные явления при приеме орлистата отмечались в основном со стороны желудочно-кишечного тракта и были обусловлены повышением количества жира в кале.\u003Cbr\u003EПри длительной терапии орлистатом количество нежелательных явлений снижается.\u003Cbr\u003EУказанные ниже побочные эффекты даются в соответствии со следующими градациями частоты их возникновения: очень часто (≥ 1/10); часто (≥ 1/100, \u003C1/10); нечасто (≥ 1/1 000,\u003Cbr\u003E\u003C1/100); редко (≥ 1/10 000, \u003C1/1 000) и очень редко (\u003C1/10 000):\u003Cbr\u003EСо стороны желудочно-кишечного тракта\u003Cbr\u003EОчень часто: маслянистые выделения из прямой кишки; газы с некоторым количеством отделяемого; императивные позывы на дефекацию; стеаторея; метеоризм; неоформленный стул.\u003Cbr\u003EЧасто: боли в животе; недержание кала; жидкий стул; увеличение частоты дефекаций.\u003Cbr\u003EПрочие\u003Cbr\u003EЧасто: тревожность.\u003Cbr\u003EНиже представлены побочные эффекты, зарегистрированные в постмаркетинговом периоде (частота неизвестна):\u003Cbr\u003EСо стороны желудочно-кишечного тракта: незначительное кровотечение из прямой кишки; дивертикулит; панкреатит.\u003Cbr\u003EСо стороны почек и мочевыводящих путей: гипероксалурия, оксалатная нефропатия, которая иногда может приводить к почечной недостаточности.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: повышение активности «печеночных» трансаминаз и щелочной фосфатазы, гепатит, желчнокаменная болезнь.\u003Cbr\u003EПрочие:\u003Cbr\u003Eснижение концентрации протромбина, повышение нормализованного отношения (МНО) у пациентов, принимавших орлистат совместно с антикоагулянтами; буллезная сыпь; реакции гиперчувствительности (зуд, сыпь, крапивница, ангионевротический отек, бронхоспазм и анафилаксия)."},{"name":"Фармакологическое действие","value":"Орлистат - специфический ингибитор желудочно-кишечных липаз длительного действия. Действует в просвете желудка и тонкого кишечника, образуя ковалентную связь с активным сериновым участком желудочной и панкреатической липаз. Инактивированный фермент не способен расщеплять жиры пищи, поступающие в виде триглицеридов, до абсорбируемых свободных жирных кислот и моноглицеридов. Нерасщепленные триглицериды не всасываются, в связи с чем, уменьшается поступление калорий в организм, что приводит к уменьшению массы тела. Терапевтическое действие препарата осуществляется без всасывания в системный кровоток. Увеличивает концентрацию жира в каловых массах через 24-48 ч после приема. Обеспечивает эффективный контроль массы тела, уменьшение доли жира.\u003Cbr\u003EУ взрослых людей с индексом массы тела (ИМТ) \u003E 28 кг/м2 орлистат в дозе 60 мг три раза в день эффективен в сочетании с гипокалорийной диетой с низким содержанием жиров. При этом, основная потеря массы тела происходит в течение первых 6 месяцев лечения. Снижение массы тела, обусловленное применением орлистата в дозе 60 мг три раза в день, сопровождается и другим благоприятным действием: снижением концентрации общего холестерина, холестерина ЛПНП, а также уменьшением окружности талии."},{"name":"Фармакологическая группа","value":"ингибиторы липазы ЖКТ"},{"name":"Форма выпуска","value":"капсулы"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °C, в оригинальной упаковке.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"У лиц с нормальной массой тела и ожирением прием однократных доз орлистата (800 мг) и многократных (до 400 мг орлистата 3 раза в день на протяжении 15 дней) не вызывал нежелательных явлений. Кроме того, у пациентов с ожирением прием орлистата в дозе 240 мг 3 раза в день на протяжении 6 месяцев не сопровождался усилением нежелательных явлений.\u003Cbr\u003EВ большинстве сообщений о случаях передозировки орлистата говорилось об отсутствии нежелательных реакций, либо нежелательные реакции были подобны тем, которые наблюдались при применении орлистата в рекомендуемых дозах.\u003Cbr\u003EВ случае значительной передозировки орлистата рекомендуется наблюдение пациента на протяжении 24 часов. По данным доклинических и клинических исследований, системные эффекты, связанные с липазингибирующими свойствами орлистата, должны быть быстро обратимыми."},{"name":"Применение при беременности и кормлении грудью","value":"Доклинические исследования не выявили тератогенного и эмбриотоксического эффекта орлистата. Однако, в связи с отсутствием клинических данных о применении у беременных, орлистат противопоказан при беременности.\u003Cbr\u003EПоскольку неизвестно, проникает ли орлистат в грудное молоко, он противопоказан в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Не выявлено какого-либо отрицательного влияния орлистата на способность управлять автотранспортными средствами и механизмами."},{"name":"Особые указания","value":"Диета и физические упражнения являются неотъемлемой частью программы снижения массы тела. Рекомендуется начинать диетическую программу и физические упражнения до начала терапии препаратом Орлистат-Акрихин.\u003Cbr\u003EВо время приема препарата Орлистат-Акрихин необходимо придерживаться дробного, сбалансированного, умеренно гипокалорийного питания, с содержанием жира не более 30% от суточной калорийности рациона (например, при рационе 2000 ккал/день\u003Cbr\u003Eпотребление жира должно составлять не более 66 г/день). Следует придерживаться полученных рекомендаций по режиму питания и физической активности, как во время, так и после прекращения приема препарата.\u003Cbr\u003EПрименение препарата Орлистат-Акрихин приводит к увеличению содержания жира в кале уже спустя 24-48 часов после начала приема. После прекращения применения препарата Орлистат-Акрихин содержание жира в кале обычно возвращается к исходному уровню в течение 48-72 часов.\u003Cbr\u003EСоблюдение диеты с низким содержанием жира уменьшает вероятность возникновения нежелательных реакций со стороны ЖКТ.\u003Cbr\u003EПрием орлистата потенциально может ухудшать всасывание жирорастворимых витаминов (A, D, E, K и бета-каротин). У подавляющего большинства пациентов, получавших орлистат в ходе четырехлетних клинических исследований, концентрация витаминов A, D, E, K и бета-каротина были в пределах нормальных значений. С профилактической целью рекомендуется принимать поливитамины на ночь.\u003Cbr\u003EПоскольку потеря массы тела обычно сопровождается улучшением показателей углеводного обмена, пациенты с сахарным диабетом 2 типа перед началом терапии препаратом Орлистат-Акрихин должны проконсультироваться с врачом и, в случае необходимости, скорректировать дозу гипогликемических препаратов.\u003Cbr\u003EСнижение массы тела при лечении может сопровождаться снижением артериального давления и концентрации ОХс в плазме крови. Пациентам, принимающим гипотензивные или гиполипидемические препараты, следует проконсультироваться с врачом и, в случае необходимости, провести коррекцию дозы этих лекарственных препаратов.\u003Cbr\u003EВ клинических исследованиях взаимодействия между контрацептивами для приема внутрь и орлистатом не наблюдалось. Однако орлистат может опосредованно снижать биодоступность контрацептивов для приема внутрь, что может привести к развитию нежелательной беременности. Рекомендуется применять дополнительные методы контрацепции в случае развития острой диареи.\u003Cbr\u003EПациентам с заболеванием почек необходимо проконсультироваться с врачом, так как возможно развитие гипероксалурии и нефропатии.\u003Cbr\u003EПациентам, принимающим амиодарон, варфарин или другие антикоагулянты для приема внутрь, также следует проконсультироваться с врачом до начала терапии орлистатом, поскольку возможны изменения показателя МНО.\u003Cbr\u003EПациентам следует прекратить прием препарата Орлистат-Акрихин и обратиться к врачу в случае появления симптомов: желтушное окрашивание склеры или кожи, кожный зуд, потемнение мочи и потеря аппетита.\u003Cbr\u003EПри применении орлистата наблюдались случаи ректального кровотечения. Если возникает это явление пациент должен проконсультироваться с врачом.\u003Cbr\u003EПри совместном применении орлистата и левотироксина натрия может развиться гипотиреоз и/или снижение контроля гипотиреоза. Пациентам, принимающим левотироксин натрия, следует проконсультироваться с врачом перед началом лечения орлистатом, т.к. может возникнуть необходимость в приеме орлистата и левотироксина натрия в разное время, а также, возможно, потребуется коррекция дозы левотироксина натрия.\u003Cbr\u003EПациентам, принимающим противоэпилептические препараты, следует проконсультироваться с врачом перед началом лечения орлистатом, т.к. они должны находиться под наблюдением в отношении возможных изменений частоты возникновения и степени выраженности судорог. В этих случаях следует рассмотреть возможность приема орлистата и противоэпилептических препаратов в разное время.\u003Cbr\u003EПациенты должны проконсультироваться с врачом перед началом применения орлистата одновременно с антиретровирусными препаратами, применяемыми для лечения ВИЧ-инфекции. Орлистат-Акрихин может уменьшать всасывание антиретровирусных препаратов и негативно влиять на их эффективность."},{"name":"Взаимодействие","value":"При одновременном применении орлистата и циклоспорина возможно снижение концентрации циклоспорина в плазме крови, в связи с чем необходимо мониторировать содержание циклоспорина в плазме крови. Одновременное применение орлистата и циклоспорина противопоказано.\u003Cbr\u003EПри одновременном применении орлистата с амиодароном рекомендуется клиническое наблюдение и мониторинг ЭКГ, так как возможно снижение концентрации амиодарона в плазме крови.\u003Cbr\u003EПри одновременном приеме орлистата и варфарина или других антикоагулянтов, может наблюдаться снижение концентрации протромбина и повышение МНО, что приводит к изменению гемостатических показателей. Одновременное применение орлистата и варфарина и других пероральных антикоагулянтов противопоказано.\u003Cbr\u003EОрлистат может уменьшать абсорбцию жирорастворимых витаминов A, D, Е, К и бета- каротина. Если показан прием поливитаминов, то их следует принимать не ранее, чем через 2 часа после приема орлистата или перед сном.\u003Cbr\u003EОрлистат может снижать всасывание противоэпилептических препаратов, что может привести к возникновению судорог.\u003Cbr\u003EС учетом отсутствия исследований фармакокинетического взаимодействия, совместного назначения орлистата и акарбозы необходимо избегать.\u003Cbr\u003EВ отдельных случаях орлистат может непрямым путем снижать биодоступность пероральных контрацептивов. В случае тяжелой диареи рекомендуется применение дополнительного метода контрацепции.\u003Cbr\u003EПри одновременном приеме с левотироксином натрия, в связи с уменьшением всасывания неорганического йода и/или левотироксина натрия, может развиться гипотиреоз и/или снижение контроля гипотиреоза.\u003Cbr\u003EНе выявлено лекарственного взаимодействия с амитриптилином, аторвастатином, бигуанидами, дигоксином, фибратами, флуоксетином, лозартаном, фенитоином, фентермином, правастатином, нифедипином, сибутрамином и этанолом."},{"name":"Регистрационный номер","value":"ЛП-002322"},{"name":"Дата государственной регистрации","value":"08.10.2019"},{"name":"Владелец регистрационного удостоверения","value":"Polpharma"},{"name":"Изготовитель","value":"Polpharma"},{"name":"Страна бренда","value":"Польша"},{"name":"Страна-производитель","value":"Польша"},{"name":"Название препарата","value":"Орлистат"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_18152351690033290906"}}}}
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Цена с картой Яндекс Пэй:817 ₽

Скидка: 1%
–1 %
Вместо: 825 ₽
  • 11 июня, курьер Маркета • 99 ₽
  • Завтра, самовывоз • 0 ₽
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  • Орсотен Слим капс., 60 мг, 42 шт.
    –2 %
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    Орсотен Слим капс., 60 мг, 42 шт.

    Рейтинг товара: 4.1 из 5
    на основе 17 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 337 ₽ вместо 1 365
    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Слим капс., 60 мг, 42 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  • Голдлайн плюс капс., 10 мг+158,5 мг, 10 шт.
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    Голдлайн плюс капс., 10 мг+158,5 мг, 10 шт.

    Рейтинг товара: 4.6 из 5
    на основе 1199 оценок
    Цена 702 ₽
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  • Орлистат-акрихин капс., 120 мг, 84 шт.
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    Орлистат-акрихин капс., 120 мг, 84 шт.

    Рейтинг товара: 4.9 из 5
    на основе 47 оценок
    Цена 3 185 ₽
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  • Орлистат-акрихин капс., 120 мг, 42 шт.
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    Орлистат-акрихин капс., 120 мг, 42 шт.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    Цена 1 689 ₽
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  • Листата таб. п/о плен., 120 мг, 20 шт.
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    Листата таб. п/о плен., 120 мг, 20 шт.

    Рейтинг товара: 4.7 из 5
    на основе 52 оценки
    Цена 1 096 ₽
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  • Редуксин капс., 10 мг+158.5 мг, 30 шт.
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    Редуксин капс., 10 мг+158.5 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 22 оценки
    Цена 2 749 ₽
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  • Целлюлоза микрокристаллическая МКЦ АНКИР-Б таб., 120 г, 100 шт., нейтральный, 1 уп.
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    Целлюлоза микрокристаллическая МКЦ АНКИР-Б таб., 120 г, 100 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.4 из 5
    на основе 244 оценки
    Цена 276 ₽
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  • Ксеникал капс., 120 мг, 21 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-osggyqxo3q/toggleWishlist":{"skuId":"662548056","productId":1400799747,"offerId":"U050YJtE1gxPoKZ7Fokmjg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQo86mm7r548EaEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIg4T6mwUQ2Nz2uwIY4tmJESDa2cEH","sign":"ju4XX67J4SxrmEFYV942X//AOFQXRcGPvpbGNcIhdNA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-osggyqxo3q/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ксеникал капс., 120 мг, 21 шт.

    Рейтинг товара: 4.8 из 5
    на основе 27 оценок
    Цена 1 012 ₽
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  • Орсотен капс., 120 мг, 21 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-7uv9rtngbb2/toggleWishlist":{"skuId":"228062718","productId":1400799424,"offerId":"2cGE-JWcZ3wONpy2c7g2Ug","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQo86mm7r548EaEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIwIH6mwUQ/uvfbBigxN4HINrZwQc=","sign":"CIAr5Stv1dXXVahBmI34OlpUSSSeBLQVG8hbOoH0hA0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-7uv9rtngbb2/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Орсотен капс., 120 мг, 21 шт.

    Рейтинг товара: 4.7 из 5
    на основе 30 оценок
    Цена 1 035 ₽
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  • Редуксин Форте таб. п/о плен., 850 мг+10 мг, 30 шт.
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    Редуксин Форте таб. п/о плен., 850 мг+10 мг, 30 шт.

    Рейтинг товара: 4.3 из 5
    на основе 13 оценок
    Цена 2 759 ₽
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Инструкция

Показания к применению

Снижение избыточной массы тела (ИМТ >28 кг/м2) при применении в сочетании с умеренно гипокалорийной диетой с низким содержанием жиров.

Противопоказания

- Повышенная чувствительность к любому из компонентов препарата;
- Синдром хронической мальабсорбции;
- Холестаз;
- Сопутствующая терапия варфарином или другими пероральными антикоагулянтами;
- Сопутствующая терапия циклоспорином;
- Период беременности и лактации;
- Детский возраст до 18 лет.

Способ применения и дозы

Внутрь, запивая водой, в рекомендуемой дозе 60 мг перед каждым основным приемом пищи, вместе с пищей или не позднее, чем через час после приема пищи. Если прием пищи пропускают или пища не содержит жира, прием орлистата также можно пропустить.
В течение 24 часов не следует принимать более 3 капсул по 60 мг.
Если через 12 недель терапии не произошло снижения массы тела, прием орлистата следует прекратить. Лечение не должно превышать 6 месяцев.
У пожилых пациентов, пациентов с нарушениями функции печени и почек коррекции дозы не требуется.
Особые группы пациентов
Пациенты пожилого возраста (> 65 лет)
Есть ограниченные данные о применении орлистата у лиц пожилого возраста. Однако, учитывая, что всасывание орлистата минимально, коррекции дозы у данной группы пациентов не требуется.
Пациенты с печеночной и почечной недостаточностью
Действие орлистата у лиц с печеночной и/или почечной недостаточностью не изучалось.
Однако, учитывая, что всасывание орлистата минимально, коррекции дозы у пациентов с печеночной и/или почечной недостаточностью не требуется.
Дети
Применение орлистата 60 мг противопоказано у детей в возрасте до 18 лет из-за недостаточности данных о безопасности и эффективности.
Полная инструкция
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Орлистат-Акрихин капс.
Орлистат-Акрихин капс., 60 мг, 42 шт.
4.6
(73)
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12 вопросов
Инструкция

Цена с картой Яндекс Пэй:817 ₽

Скидка: 1%
–1 %
Вместо: 825 ₽
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4.6
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У продавца:73 оценки·8 отзывов
У всех продавцов:443 оценки·122 отзыва
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user avatar
3 недели назад • Татьяна • Куплен на Маркете
Достоинства: Дней через 10 я начала заметно скидывать в объёмах. Часто плаваю, много хожу, не очень калорийно питаюсь, но раньше начать терять вес не получалось. Сейчас процесс пошёл. Ем не очень жирную пищу, поэтому всех побочных эффектов удается в целом избежать. Если уж так получается, что жирненькое попалось - ну да, это становится заметно в процессе посещения туалета. Но ничего ниоткуда не вытекает и никакого недержания нет, как иногда пишут страшилки о побочках)
Недостатки: Я не заметила. Обо всех побочных эффектах написано в инструкции, поэтому они логичны и ожидаемы при употреблении жирной еды.
Комментарий: Я очень довольна, пью уже вторую упаковку.
user avatar
5 месяцев назад • Елена • Куплен на Маркете
Достоинства: хорошие таблетки и капсулы
Недостатки: нет
Комментарий: советую
user avatar
5 месяцев назад • Изабелла Каркошкина • Куплен на Маркете
Достоинства: эффективно
Недостатки: нет
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