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Описание

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Ципрофлоксацин таб. п/о плен., 500 мг, 10 шт.

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4.9
(20)
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Дозировка: 500 мг

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Коротко о товаре

Артикул Маркета
3123140224
Тип препарата
Назначение
Действующее вещество
Форма выпуска
таблетки, покрытые пленочной оболочкой
Инструкция
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отит","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["36476390:36619067,36618553,36618372,36618338,36618132,36618018,36617693,36617637,36617383,36617320"]}}},{"name":"Органы и системы","value":"глаза, дыхательная система, кожа, мочевой пузырь, мочеточники, половая система, почки, уши"},{"name":"Показания к применению","value":"инфекционно-воспалительные заболевания, вызванные чувствительными микроорганизмами:\u003Cbr\u003E- заболевания нижних дыхательных путей (острый и хронический (в стадии обострения) бронхит, пневмония, бронхоэктатическая болезнь, инфекционные осложнения муковисцидоза);\u003Cbr\u003E- инфекции ЛОР-органов (острый синусит);\u003Cbr\u003E- инфекции почек и мочевыводящих путей (цистит, пиелонефрит);\u003Cbr\u003E- осложненные интраабдоминальные инфекции (в комбинации с метронидазолом);\u003Cbr\u003E- хронический бактериальный простатит;\u003Cbr\u003E- неосложненная гонорея;\u003Cbr\u003E- брюшной тиф,\u003Cbr\u003E- инфекционная диарея, в том числе кампилобактериоз, шигеллез, диарея “путешественников”;\u003Cbr\u003E- инфекции кожи и мягких тканей (инфицированные язвы, раны, ожоги, абсцессы, флегмона);\u003Cbr\u003E- костей и суставов (остеомиелит, септический артрит);\u003Cbr\u003E- инфекции на фоне иммунодефицита (возникающего при лечении иммунодепрессивными лекарственными средствами или у больных с нейтропенией);\u003Cbr\u003E- профилактика и лечение легочной формы сибирской язвы.\u003Cbr\u003EДети.\u003Cbr\u003E- терапия осложнений, вызванных Pseudomonas aeruginosa у детей с муковисцидозом легких от 5 до 17 лет;\u003Cbr\u003E- профилактика и лечение легочной формы сибирской язвы (инфицирование Bacillus anthracis)."},{"name":"Противопоказания","value":"-гиперчувствительность; -одновременный прием с тизанидином (риск выраженного снижения артериального давления, сонливости); -возраст до 18 лет (до завершения процесса формирования скелета, кроме терапии осложнений, вызванных Pseudomonas aeruginosa у детей с муковисцидозом легких от 5 до 17 лет; -профилактики и лечения легочной формы сибирской язвы), беременность, период лактации."},{"name":"Состав","value":"Состав на 1 таблетку 250 мг:\u003Cbr\u003EАктивное вещество: ципрофлоксацина гидрохлорида моногидрат в пересчете на ципрофлоксацин - 250 мг;\u003Cbr\u003EВспомогательные вещества (ядро): кросповидон - 7 мг, целлюлоза микрокристаллическая - 43,9 мг, повидон (поливинилпирролидон) - 16,3 мг, магния стеарат - 3,7 мг, крахмал кукурузный -13,0 мг. Вспомогательные вещества (оболочка): гипромеллоза - 8,5 мг, титана диоксид - 4,5 мг, макрогол - 2,0 мг.\u003Cbr\u003EСостав на 1 таблетку 500 мг:\u003Cbr\u003EАктивное вещество: ципрофлоксацина гидрохлорид 582,25 мг, в пересчете на ципрофлоксацин 500,00 мг. Вспомогательные вещества (ядро): крахмал кукурузный - 13,00 мг, целлюлоза микрокристаллическая - 10,85 мг, повидон-К25 - 28,70 мг, карбоксиметилкрахмал натрия - 9,90 мг, кремния диоксид коллоидный - 0,10 мг, магния стеарат - 6,50 мг, кросповидон - 8,70 мг. Вспомогательные вещества (оболочка): гипромеллоза - 11,33 мг, макрогол-4000 - 2,67 мг, титана диоксид - 6,00 мг."},{"name":"Действующее вещество","value":"Ципрофлоксацин","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28708674"]}}},{"name":"Способ применения и дозы","value":"Внутрь. Таблетки следует проглатывать целиком с небольшим количеством жидкости после еды. При приеме таблетки натощак активное вещество всасывается быстрее.\u003Cbr\u003EПри инфекциях нижних дыхательных путей легкой и средней степени - 0.5 г 2 раза в сутки, при тяжелом течении - 0.75 г 2 раза. Курс лечения - 7-14 дней.\u003Cbr\u003EПри остром синусите - по 0.5 г 2 раза в сутки. Курс лечения - 10 дней.\u003Cbr\u003EПри инфекции кожи и мягких тканей легкой и средней степени - 0.5 г 2 раза в сутки, при тяжелом течении-0.75 г 2 раза. Курс лечения - 7-14 дней.\u003Cbr\u003EПри инфекциях костей и суставов - легкой и средней степени - 0.5 г2 раза в сутки, при тяжелом течении -0.75 г 2 раза. Курс лечения - до 4-6 нед.\u003Cbr\u003EПри инфекциях мочевыводящих путей - по 0.25-0.5 г 2 раза в сутки; курс лечения - 7-14 дней, при неосложненном цистите у женщин - 3 дня.\u003Cbr\u003EПри хроническом бактериальном простатите - по 0.5 г 2 раза, курс лечения - 28 дней.\u003Cbr\u003EПри неосложненной гонорее - 0.25-0.5 г однократно.\u003Cbr\u003EИнфекционная диарея - по 0.5 г 2 раза, курс лечения - 5-7 дней. При брюшном тифе - по 0.5 г 2 раза; курс лечения - 10 дней.\u003Cbr\u003EПри осложненных интраабдоминальных инфекциях - по 0.5 г каждые 12 ч в течение 7-14 дней.\u003Cbr\u003EДля профилактики и лечения легочной формы сибирской язвы - по 0.5 г 2 раза в сутки в течение 60 дней.\u003Cbr\u003EДругие инфекции (см. \"Показания к применению\") - по 0.5 г 2 раза в сутки.\u003Cbr\u003EВ педиатрии\u003Cbr\u003Eпри лечении осложнений, вызванных Pseudomonas aeruginosa, у детей с муковисцидозом легких от 5 до 17 лет - 20 мг/кг 2 раза в сутки (максимальная доза 1.5 г).\u003Cbr\u003EПродолжительность лечения - 10-14 дней.\u003Cbr\u003EПри легочной форме сибирской язвы (профилактика и лечение) - 15 мг/кг2 раза вдень.\u003Cbr\u003EМаксимальная разовая доза - 0.5 г, суточная - 1г. Общая продолжительность приема ципрофлоксацина - 60 дней.\u003Cbr\u003EХроническая почечная недостаточность: при КК более 50 мл/мин коррекции дозы не требуется; при КК 30-50 мл/мин - 0.25-0.5 каждые 12 ч; при КК 5-29 мл/мин - 0.25-0.5 г каждые 18 ч. Если больному проводится гемодиализ или перитонеальный диализ - 0.25-0.5 г/сут, но принимать препарат следует после сеанса гемодиализа."},{"name":"Побочные действия","value":"Со стороны пищеварительной системы: тошнота, диарея, рвота, боль в животе, метеоризм, снижение аппетита, холестатическая желтуха (особенно у пациентов с перенесенными заболеваниями печени), гепатит, гепатонекроз.\u003Cbr\u003EСо стороны нервной системы: головокружение, головная боль, повышенная утомляемость, тревожность, тремор, бессонница, “кошмарные” сновидения, периферическая паралгезия (аномалия восприятия чувства боли), повышенное потоотделение, повышение внутричерепного давления, спутанность сознания, депрессия, галлюцинации, а также другие проявления психотических реакций (изредка прогрессирующих до состояний, в которых пациент может причинить себе вред), мигрень, обмороки, тромбоз церебральных артерий.\u003Cbr\u003EСо стороны органов чувств: нарушения вкуса и обоняния, нарушение зрения (диплопия, изменение цветовосприятия), шум в ушах, снижение слуха.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: тахикардия, нарушения сердечного ритма, снижение артериального давления.\u003Cbr\u003EСо стороны кроветворной системы: лейкопения, гранулоцитопения, анемия, тромбоцитопения, лейкоцитоз, тромбоцитоз, гемолитическая анемия.\u003Cbr\u003EЛабораторные показатели: гипопротромбинемия, повышение активности “печеночных” трансаминаз и щелочной фосфатазы, гиперкреатининемия, гипербилирубинемия, гипергликемия.\u003Cbr\u003EСо стороны моче выделительной системы: гематурия, кристаллурия (прежде всего при щелочной моче и низком диурезе), гломерулонефрит, дизурия, полиурия, задержка мочи, альбуминурия, уретральные кровотечения, снижение азотовыделительной функции почек, интерстициальный нефрит.\u003Cbr\u003EАллергические реакции: кожный зуд, крапивница, образование волдырей, сопровождающихся кровотечениями, и появление маленьких узелков, образующих струпья, лекарственная лихорадка, точечные кровоизлияния на коже (петехии), отек лица или гортани, одышка, эозинофилия, васкулит, узловатая эритема, мультиформная экссудативная эритема (в т.ч. синдром Стивенса-Джонсона), токсический эпидермальный некролиз (синдром Лайелла).\u003Cbr\u003EСо стороны опорно-двигательного аппарата: артралгия, артрит, тендовагинит, разрывы сухожилий, миалгия.\u003Cbr\u003EПрочие: астения, повышенная светочувствительность, суперинфекции (кандидоз, псевдомембранозный колит), “приливы\" крови к лицу."},{"name":"Фармакологическое действие","value":"Противомикробное средство широкого спектра действия, производное хинолона, подавляет бактериальную ДНК-гиразу (топоизомеразы II и IV, ответственные за процесс суперспирализации хромосомной ДНК вокруг ядерной РНК, что необходимо для считывания генетической информации), нарушает синтез ДНК, рост и деление бактерий; вызывает выраженные морфологические изменения (в т.ч. клеточной стенки и мембран) и быструю гибель бактериальной клетки.\u003Cbr\u003EДействует бактерицидно на грамотрицательные микроорганизмы в период покоя и деления (т.к. влияет не только на ДНК-гиразу, но и вызывает лизис клеточной стенки), на грамположительные микроорганизмы - только в период деления.\u003Cbr\u003EНизкая токсичность для клеток макроорганизма объясняется отсутствием в них ДНК-гиразы. На фоне приема ципрофлоксацина не происходит параллельной выработки устойчивости к другим антибиотикам, не принадлежащим к группе ингибиторов ДНК-гиразы, что делает его высокоэффективным по отношению к бактериям, которые устойчивы, например, к аминогликозидам, пенициллинам, цефалоспоринам, тетрациклинам.\u003Cbr\u003EК ципрофлоксацину чувствительны грамотрицательные аэробные бактерии: энтеробактерии (Escherichia coli, Salmonella spp., Shigella spp., Citrobacter spp., Klebsiella spp., Enterobacter spp., Proteus mirabilis, Proteus vulgaris, Serratia marcescens, Hafnia alvei, Edwardsiella tarda, Providencia spp., Morganella morganii, Vibrio spp., Yersinia spp), другие грамотрицательные бактерии (Haemophilus spp., Pseudomonas aeruginosa, Moraxella catarrhalis, Aeromonas spp., Pasteurella multocida, Plesiomonas shigelloides, Campylobacter jejuni, Neisseria spp.), некоторые внутриклеточные возбудители - Legionella pneumophila, Brucella spp., Listeria monocytogenes, Mycobacterium tuberculosis, Mycobacterium kansasii.\u003Cbr\u003EГрамположительные аэробные бактерии: Staphylococcus spp. (Staphylococcus aureus, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus saprophyticus), Streptococcus spp. (Streptococcus pyogenes, Streptococcus agalactiae). К ципрофлоксацину также чувствителен Bacillus anthracis.\u003Cbr\u003EБольшинство стафилококков, устойчивых к метициллину, резистентны и к ципрофлоксацину. Чувствительность Streptococcus pneumoniae, Enterococcus faecalis, Mycobacterium avium (расположенных внутриклеточно) - умеренная (для их подавления требуются высокие концентрации).\u003Cbr\u003EК препарату резистентны: Bacteroides fragilis, Pseudomonas cepacia, Pseudomonas maltophilia, Ureaplasma urealyticum, Clostridium difficile, Nocardia asteroides. He эффективен в отношении Treponema pallidum. Резистентность развивается крайне медленно, поскольку, с одной стороны, после действия ципрофлоксацина практически не остается персистирующих микроорганизмов, а с другой - у бактериальных клеток нет ферментов, инактивирующих его."},{"name":"Фармакологическая группа","value":"противомикробное средство - фторхинолон"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["35947170:36763744"]}}},{"name":"Условия хранения","value":"В защищенном от света месте при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Лечение: специфический антидот неизвестен. Промывание желудка и другие меры неотложной помощи, тщательный контроль состояния пациента, обеспечение достаточного поступления жидкости. С помощью гемо- или перитонеального диализа может быть выведено лишь незначительное (менее 10%) количество препарата."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказан."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Во время лечения следует воздерживаться от занятий потенциально опасными видами деятельности, требующими повышенного внимания и быстроты психических и двигательных реакций."},{"name":"Особые указания","value":"Ципрофлоксацин не является препаратом выбора при подозреваемой или установленной пневмонии, вызванной Streptococcus pneumoniae. Во избежание развития кристаллурии недопустимо превышение рекомендованной суточной дозы, необходимо также достаточное потребление жидкости и поддержание кислой реакции мочи.\u003Cbr\u003EБольным с эпилепсией, приступами судорог в анамнезе, сосудистыми заболеваниями и органическими поражениями головного мозга, в связи с угрозой развития побочных реакций со стороны центральной нервной системы ципрофлоксацин следует назначать только по “жизненным” показаниям.\u003Cbr\u003EПри возникновении во время или после лечения тяжелой и длительной диареи следует исключить диагноз псевдомембранозного колита, который требует немедленной отмены препарата и назначения соответствующего лечения.\u003Cbr\u003EПри появлении болей в сухожилиях или первых признаков тендовагинита лечение следует прекратить (описаны отдельные случаи воспаления и даже разрыва сухожилий во время лечения фторхинолонами).\u003Cbr\u003EВ период лечения следует избегать УФ-облучения (в том числе контакта с прямыми солнечными лучами).\u003Cbr\u003EС осторожностью:\u003Cbr\u003EВыраженный атеросклероз сосудов головного мозга, нарушение мозгового кровообращения, психические заболевания, эпилепсия, выраженная почечная и/или печеночная недостаточность, поражение сухожилий при ранее проводившемся лечении фторхинолонами, пожилой возраст."},{"name":"Взаимодействие","value":"Вследствие снижения активности процессов микросомального окисления в гепатоцитах повышает концентрацию и удлиняет Т1/2 теофиллина (и других ксантинов, например, кофеина), пероральных гипогликемических лекарственных средств, непрямых антикоагулянтов, способствует снижению протромбинового индекса.\u003Cbr\u003EПри сочетании с другими противомикробными лекарственными средствами (бета-лактамные антибиотики, аминогликозиды, клиндамицин, метронидазол) обычно наблюдается синергизм; может успешно применяться в комбинации с азлоциллином и цефтазидимом при инфекциях, вызванных Pseudomonas spp.; с мезлоциллином, азлоциллином и другими бета-лактамными антибиотиками - при стрептококковых инфекциях; с изоксазолилпенициллинами и ванкомицином - при стафилококковых инфекциях; с метронидазол ом и клиндамицином - при анаэробных инфекциях.\u003Cbr\u003EУсиливает нефротоксическое действие циклоспорина, отмечается увеличение сывороточного креатинина, у таких пациентов необходим контроль этого показателя 2 раза в неделю.\u003Cbr\u003EПри одновременном приеме усиливает действие непрямых антикоагулянтов.\u003Cbr\u003EПероральный прием совместно с железосодержащими лекарственными средствами, сукральфатом и антацидными лекарственными средствами, содержащими ионы магния, кальция, алюминия, приводит к снижению всасывания ципрофлоксацина, поэтому его следует назначать за 1-2 ч до или через 4 ч после приема вышеуказанных лекарственных средств.\u003Cbr\u003EНестероидные противовоспалительные препараты (исключая ацетилсалициловую кислоту) повышают риск развития судорог.\u003Cbr\u003EДиданозин снижает всасывание ципрофлоксацина вследствие образования с ним комплексов с содержащимися в диданозине ионами кальция, железа и магния.\u003Cbr\u003EМетоклопрамид ускоряет абсорбцию, что приводит к уменьшению времени достижения его Смах.\u003Cbr\u003EСовместное применение урикозурических лекарственных средств приводит к замедлению выведения (до 50%) и повышению плазменной концентрации ципрофлоксацина.\u003Cbr\u003EПовышает Смах в 7 раз (от 4 до 21 раза) и площадь под фармакологической кривой \"концентрация-время\" (AUC) в 10 раз (от 6 до 24 раз) тизанидина, что повышает риск выраженного снижения артериального давления и сонливости."},{"name":"Регистрационный номер","value":"Р N003190/01\nЛП-№(000964)-(РГ-RU)\nЛСР-003299/07\nЛП-№(000641)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"17.08.2020\n01.07.2022\n04.09.2020\n24.03.2022"},{"name":"Владелец регистрационного удостоверения","value":"ОЗОН Фармацевтика","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["34324371:35649313","7893318:13891799"]}}},{"name":"Изготовитель","value":"ОЗОН"},{"name":"Фасовщик","value":"ОЗОН"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Ципрофлоксацин","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["17796364:18036884"]}}},{"name":"Срок годности","value":"961 дн."}]}},"fullSpecsGrouped":{"3141738958087526337":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Назначение","value":"бактериальные инфекции верхних отделов дыхательных путей и ЛОР-органов, бактериальные инфекции глаз, бактериальные инфекции нижних отделов дыхательных путей, воспалительные заболевания половых органов, инфекции кожи и мягких тканей, инфекции мочевыводящих путей, инфекционно-воспалительные заболевания, вызванные чувствительными микроорганизмами, профилактика и лечение сибирской язвы, синусит, средний отит"},{"name":"Органы и системы","value":"глаза, дыхательная система, кожа, мочевой пузырь, мочеточники, половая система, почки, уши"},{"name":"Показания к применению","value":"инфекционно-воспалительные заболевания, вызванные чувствительными микроорганизмами:\u003Cbr\u003E- заболевания нижних дыхательных путей (острый и хронический (в стадии обострения) бронхит, пневмония, бронхоэктатическая болезнь, инфекционные осложнения муковисцидоза);\u003Cbr\u003E- инфекции ЛОР-органов (острый синусит);\u003Cbr\u003E- инфекции почек и мочевыводящих путей (цистит, пиелонефрит);\u003Cbr\u003E- осложненные интраабдоминальные инфекции (в комбинации с метронидазолом);\u003Cbr\u003E- хронический бактериальный простатит;\u003Cbr\u003E- неосложненная гонорея;\u003Cbr\u003E- брюшной тиф,\u003Cbr\u003E- инфекционная диарея, в том числе кампилобактериоз, шигеллез, диарея “путешественников”;\u003Cbr\u003E- инфекции кожи и мягких тканей (инфицированные язвы, раны, ожоги, абсцессы, флегмона);\u003Cbr\u003E- костей и суставов (остеомиелит, септический артрит);\u003Cbr\u003E- инфекции на фоне иммунодефицита (возникающего при лечении иммунодепрессивными лекарственными средствами или у больных с нейтропенией);\u003Cbr\u003E- профилактика и лечение легочной формы сибирской язвы.\u003Cbr\u003EДети.\u003Cbr\u003E- терапия осложнений, вызванных Pseudomonas aeruginosa у детей с муковисцидозом легких от 5 до 17 лет;\u003Cbr\u003E- профилактика и лечение легочной формы сибирской язвы (инфицирование Bacillus anthracis)."},{"name":"Противопоказания","value":"-гиперчувствительность; -одновременный прием с тизанидином (риск выраженного снижения артериального давления, сонливости); -возраст до 18 лет (до завершения процесса формирования скелета, кроме терапии осложнений, вызванных Pseudomonas aeruginosa у детей с муковисцидозом легких от 5 до 17 лет; -профилактики и лечения легочной формы сибирской язвы), беременность, период лактации."},{"name":"Состав","value":"Состав на 1 таблетку 250 мг:\u003Cbr\u003EАктивное вещество: ципрофлоксацина гидрохлорида моногидрат в пересчете на ципрофлоксацин - 250 мг;\u003Cbr\u003EВспомогательные вещества (ядро): кросповидон - 7 мг, целлюлоза микрокристаллическая - 43,9 мг, повидон (поливинилпирролидон) - 16,3 мг, магния стеарат - 3,7 мг, крахмал кукурузный -13,0 мг. Вспомогательные вещества (оболочка): гипромеллоза - 8,5 мг, титана диоксид - 4,5 мг, макрогол - 2,0 мг.\u003Cbr\u003EСостав на 1 таблетку 500 мг:\u003Cbr\u003EАктивное вещество: ципрофлоксацина гидрохлорид 582,25 мг, в пересчете на ципрофлоксацин 500,00 мг. Вспомогательные вещества (ядро): крахмал кукурузный - 13,00 мг, целлюлоза микрокристаллическая - 10,85 мг, повидон-К25 - 28,70 мг, карбоксиметилкрахмал натрия - 9,90 мг, кремния диоксид коллоидный - 0,10 мг, магния стеарат - 6,50 мг, кросповидон - 8,70 мг. Вспомогательные вещества (оболочка): гипромеллоза - 11,33 мг, макрогол-4000 - 2,67 мг, титана диоксид - 6,00 мг."},{"name":"Действующее вещество","value":"Ципрофлоксацин"},{"name":"Способ применения и дозы","value":"Внутрь. Таблетки следует проглатывать целиком с небольшим количеством жидкости после еды. При приеме таблетки натощак активное вещество всасывается быстрее.\u003Cbr\u003EПри инфекциях нижних дыхательных путей легкой и средней степени - 0.5 г 2 раза в сутки, при тяжелом течении - 0.75 г 2 раза. Курс лечения - 7-14 дней.\u003Cbr\u003EПри остром синусите - по 0.5 г 2 раза в сутки. Курс лечения - 10 дней.\u003Cbr\u003EПри инфекции кожи и мягких тканей легкой и средней степени - 0.5 г 2 раза в сутки, при тяжелом течении-0.75 г 2 раза. Курс лечения - 7-14 дней.\u003Cbr\u003EПри инфекциях костей и суставов - легкой и средней степени - 0.5 г2 раза в сутки, при тяжелом течении -0.75 г 2 раза. Курс лечения - до 4-6 нед.\u003Cbr\u003EПри инфекциях мочевыводящих путей - по 0.25-0.5 г 2 раза в сутки; курс лечения - 7-14 дней, при неосложненном цистите у женщин - 3 дня.\u003Cbr\u003EПри хроническом бактериальном простатите - по 0.5 г 2 раза, курс лечения - 28 дней.\u003Cbr\u003EПри неосложненной гонорее - 0.25-0.5 г однократно.\u003Cbr\u003EИнфекционная диарея - по 0.5 г 2 раза, курс лечения - 5-7 дней. При брюшном тифе - по 0.5 г 2 раза; курс лечения - 10 дней.\u003Cbr\u003EПри осложненных интраабдоминальных инфекциях - по 0.5 г каждые 12 ч в течение 7-14 дней.\u003Cbr\u003EДля профилактики и лечения легочной формы сибирской язвы - по 0.5 г 2 раза в сутки в течение 60 дней.\u003Cbr\u003EДругие инфекции (см. \"Показания к применению\") - по 0.5 г 2 раза в сутки.\u003Cbr\u003EВ педиатрии\u003Cbr\u003Eпри лечении осложнений, вызванных Pseudomonas aeruginosa, у детей с муковисцидозом легких от 5 до 17 лет - 20 мг/кг 2 раза в сутки (максимальная доза 1.5 г).\u003Cbr\u003EПродолжительность лечения - 10-14 дней.\u003Cbr\u003EПри легочной форме сибирской язвы (профилактика и лечение) - 15 мг/кг2 раза вдень.\u003Cbr\u003EМаксимальная разовая доза - 0.5 г, суточная - 1г. Общая продолжительность приема ципрофлоксацина - 60 дней.\u003Cbr\u003EХроническая почечная недостаточность: при КК более 50 мл/мин коррекции дозы не требуется; при КК 30-50 мл/мин - 0.25-0.5 каждые 12 ч; при КК 5-29 мл/мин - 0.25-0.5 г каждые 18 ч. Если больному проводится гемодиализ или перитонеальный диализ - 0.25-0.5 г/сут, но принимать препарат следует после сеанса гемодиализа."},{"name":"Побочные действия","value":"Со стороны пищеварительной системы: тошнота, диарея, рвота, боль в животе, метеоризм, снижение аппетита, холестатическая желтуха (особенно у пациентов с перенесенными заболеваниями печени), гепатит, гепатонекроз.\u003Cbr\u003EСо стороны нервной системы: головокружение, головная боль, повышенная утомляемость, тревожность, тремор, бессонница, “кошмарные” сновидения, периферическая паралгезия (аномалия восприятия чувства боли), повышенное потоотделение, повышение внутричерепного давления, спутанность сознания, депрессия, галлюцинации, а также другие проявления психотических реакций (изредка прогрессирующих до состояний, в которых пациент может причинить себе вред), мигрень, обмороки, тромбоз церебральных артерий.\u003Cbr\u003EСо стороны органов чувств: нарушения вкуса и обоняния, нарушение зрения (диплопия, изменение цветовосприятия), шум в ушах, снижение слуха.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: тахикардия, нарушения сердечного ритма, снижение артериального давления.\u003Cbr\u003EСо стороны кроветворной системы: лейкопения, гранулоцитопения, анемия, тромбоцитопения, лейкоцитоз, тромбоцитоз, гемолитическая анемия.\u003Cbr\u003EЛабораторные показатели: гипопротромбинемия, повышение активности “печеночных” трансаминаз и щелочной фосфатазы, гиперкреатининемия, гипербилирубинемия, гипергликемия.\u003Cbr\u003EСо стороны моче выделительной системы: гематурия, кристаллурия (прежде всего при щелочной моче и низком диурезе), гломерулонефрит, дизурия, полиурия, задержка мочи, альбуминурия, уретральные кровотечения, снижение азотовыделительной функции почек, интерстициальный нефрит.\u003Cbr\u003EАллергические реакции: кожный зуд, крапивница, образование волдырей, сопровождающихся кровотечениями, и появление маленьких узелков, образующих струпья, лекарственная лихорадка, точечные кровоизлияния на коже (петехии), отек лица или гортани, одышка, эозинофилия, васкулит, узловатая эритема, мультиформная экссудативная эритема (в т.ч. синдром Стивенса-Джонсона), токсический эпидермальный некролиз (синдром Лайелла).\u003Cbr\u003EСо стороны опорно-двигательного аппарата: артралгия, артрит, тендовагинит, разрывы сухожилий, миалгия.\u003Cbr\u003EПрочие: астения, повышенная светочувствительность, суперинфекции (кандидоз, псевдомембранозный колит), “приливы\" крови к лицу."},{"name":"Фармакологическое действие","value":"Противомикробное средство широкого спектра действия, производное хинолона, подавляет бактериальную ДНК-гиразу (топоизомеразы II и IV, ответственные за процесс суперспирализации хромосомной ДНК вокруг ядерной РНК, что необходимо для считывания генетической информации), нарушает синтез ДНК, рост и деление бактерий; вызывает выраженные морфологические изменения (в т.ч. клеточной стенки и мембран) и быструю гибель бактериальной клетки.\u003Cbr\u003EДействует бактерицидно на грамотрицательные микроорганизмы в период покоя и деления (т.к. влияет не только на ДНК-гиразу, но и вызывает лизис клеточной стенки), на грамположительные микроорганизмы - только в период деления.\u003Cbr\u003EНизкая токсичность для клеток макроорганизма объясняется отсутствием в них ДНК-гиразы. На фоне приема ципрофлоксацина не происходит параллельной выработки устойчивости к другим антибиотикам, не принадлежащим к группе ингибиторов ДНК-гиразы, что делает его высокоэффективным по отношению к бактериям, которые устойчивы, например, к аминогликозидам, пенициллинам, цефалоспоринам, тетрациклинам.\u003Cbr\u003EК ципрофлоксацину чувствительны грамотрицательные аэробные бактерии: энтеробактерии (Escherichia coli, Salmonella spp., Shigella spp., Citrobacter spp., Klebsiella spp., Enterobacter spp., Proteus mirabilis, Proteus vulgaris, Serratia marcescens, Hafnia alvei, Edwardsiella tarda, Providencia spp., Morganella morganii, Vibrio spp., Yersinia spp), другие грамотрицательные бактерии (Haemophilus spp., Pseudomonas aeruginosa, Moraxella catarrhalis, Aeromonas spp., Pasteurella multocida, Plesiomonas shigelloides, Campylobacter jejuni, Neisseria spp.), некоторые внутриклеточные возбудители - Legionella pneumophila, Brucella spp., Listeria monocytogenes, Mycobacterium tuberculosis, Mycobacterium kansasii.\u003Cbr\u003EГрамположительные аэробные бактерии: Staphylococcus spp. (Staphylococcus aureus, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus saprophyticus), Streptococcus spp. (Streptococcus pyogenes, Streptococcus agalactiae). К ципрофлоксацину также чувствителен Bacillus anthracis.\u003Cbr\u003EБольшинство стафилококков, устойчивых к метициллину, резистентны и к ципрофлоксацину. Чувствительность Streptococcus pneumoniae, Enterococcus faecalis, Mycobacterium avium (расположенных внутриклеточно) - умеренная (для их подавления требуются высокие концентрации).\u003Cbr\u003EК препарату резистентны: Bacteroides fragilis, Pseudomonas cepacia, Pseudomonas maltophilia, Ureaplasma urealyticum, Clostridium difficile, Nocardia asteroides. He эффективен в отношении Treponema pallidum. Резистентность развивается крайне медленно, поскольку, с одной стороны, после действия ципрофлоксацина практически не остается персистирующих микроорганизмов, а с другой - у бактериальных клеток нет ферментов, инактивирующих его."},{"name":"Фармакологическая группа","value":"противомикробное средство - фторхинолон"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Лечение: специфический антидот неизвестен. Промывание желудка и другие меры неотложной помощи, тщательный контроль состояния пациента, обеспечение достаточного поступления жидкости. С помощью гемо- или перитонеального диализа может быть выведено лишь незначительное (менее 10%) количество препарата."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказан."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Во время лечения следует воздерживаться от занятий потенциально опасными видами деятельности, требующими повышенного внимания и быстроты психических и двигательных реакций."},{"name":"Особые указания","value":"Ципрофлоксацин не является препаратом выбора при подозреваемой или установленной пневмонии, вызванной Streptococcus pneumoniae. Во избежание развития кристаллурии недопустимо превышение рекомендованной суточной дозы, необходимо также достаточное потребление жидкости и поддержание кислой реакции мочи.\u003Cbr\u003EБольным с эпилепсией, приступами судорог в анамнезе, сосудистыми заболеваниями и органическими поражениями головного мозга, в связи с угрозой развития побочных реакций со стороны центральной нервной системы ципрофлоксацин следует назначать только по “жизненным” показаниям.\u003Cbr\u003EПри возникновении во время или после лечения тяжелой и длительной диареи следует исключить диагноз псевдомембранозного колита, который требует немедленной отмены препарата и назначения соответствующего лечения.\u003Cbr\u003EПри появлении болей в сухожилиях или первых признаков тендовагинита лечение следует прекратить (описаны отдельные случаи воспаления и даже разрыва сухожилий во время лечения фторхинолонами).\u003Cbr\u003EВ период лечения следует избегать УФ-облучения (в том числе контакта с прямыми солнечными лучами).\u003Cbr\u003EС осторожностью:\u003Cbr\u003EВыраженный атеросклероз сосудов головного мозга, нарушение мозгового кровообращения, психические заболевания, эпилепсия, выраженная почечная и/или печеночная недостаточность, поражение сухожилий при ранее проводившемся лечении фторхинолонами, пожилой возраст."},{"name":"Взаимодействие","value":"Вследствие снижения активности процессов микросомального окисления в гепатоцитах повышает концентрацию и удлиняет Т1/2 теофиллина (и других ксантинов, например, кофеина), пероральных гипогликемических лекарственных средств, непрямых антикоагулянтов, способствует снижению протромбинового индекса.\u003Cbr\u003EПри сочетании с другими противомикробными лекарственными средствами (бета-лактамные антибиотики, аминогликозиды, клиндамицин, метронидазол) обычно наблюдается синергизм; может успешно применяться в комбинации с азлоциллином и цефтазидимом при инфекциях, вызванных Pseudomonas spp.; с мезлоциллином, азлоциллином и другими бета-лактамными антибиотиками - при стрептококковых инфекциях; с изоксазолилпенициллинами и ванкомицином - при стафилококковых инфекциях; с метронидазол ом и клиндамицином - при анаэробных инфекциях.\u003Cbr\u003EУсиливает нефротоксическое действие циклоспорина, отмечается увеличение сывороточного креатинина, у таких пациентов необходим контроль этого показателя 2 раза в неделю.\u003Cbr\u003EПри одновременном приеме усиливает действие непрямых антикоагулянтов.\u003Cbr\u003EПероральный прием совместно с железосодержащими лекарственными средствами, сукральфатом и антацидными лекарственными средствами, содержащими ионы магния, кальция, алюминия, приводит к снижению всасывания ципрофлоксацина, поэтому его следует назначать за 1-2 ч до или через 4 ч после приема вышеуказанных лекарственных средств.\u003Cbr\u003EНестероидные противовоспалительные препараты (исключая ацетилсалициловую кислоту) повышают риск развития судорог.\u003Cbr\u003EДиданозин снижает всасывание ципрофлоксацина вследствие образования с ним комплексов с содержащимися в диданозине ионами кальция, железа и магния.\u003Cbr\u003EМетоклопрамид ускоряет абсорбцию, что приводит к уменьшению времени достижения его Смах.\u003Cbr\u003EСовместное применение урикозурических лекарственных средств приводит к замедлению выведения (до 50%) и повышению плазменной концентрации ципрофлоксацина.\u003Cbr\u003EПовышает Смах в 7 раз (от 4 до 21 раза) и площадь под фармакологической кривой \"концентрация-время\" (AUC) в 10 раз (от 6 до 24 раз) тизанидина, что повышает риск выраженного снижения артериального давления и сонливости."},{"name":"Регистрационный номер","value":"Р N003190/01\nЛП-№(000964)-(РГ-RU)\nЛСР-003299/07\nЛП-№(000641)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"17.08.2020\n01.07.2022\n04.09.2020\n24.03.2022"},{"name":"Владелец регистрационного удостоверения","value":"ОЗОН Фармацевтика"},{"name":"Изготовитель","value":"ОЗОН"},{"name":"Фасовщик","value":"ОЗОН"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Ципрофлоксацин"},{"name":"Срок годности","value":"961 дн."}]}],"transitionId":"tr_982407401138763440"}}}}
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    Ципролет таб. п/о плен., 500 мг, 10 шт.

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    Цена 113 ₽
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  • Амоксициллин капс., 500 мг, 16 шт.
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    Амоксициллин капс., 500 мг, 16 шт.

    Рейтинг товара: 4.9 из 5
    на основе 64 оценки
    Цена 115 ₽
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  • Азитромицин капс., 250 мг, 6 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k8zcftjleg/toggleWishlist":{"skuId":"186882187","productId":1434054437,"offerId":"SpJ0LUDKY_Bz7nu0CBi7UQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpqD5wvje0rp1EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIpd7nqwUQi7GOWRjkpNUHIPfcwQc=","sign":"Wk0TDDfrDhb/JvQ/zQtNe0zRrrn4HYYiCXBHoLwkWNs="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k8zcftjleg/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Азитромицин капс., 250 мг, 6 шт.

    Рейтинг товара: 4.7 из 5
    на основе 156 оценок
    Цена 83 ₽
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  • Ципрофлоксацин таб. п/о плен., 500 мг, 10 шт.
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    Ципрофлоксацин таб. п/о плен., 500 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 98 ₽
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  • Азитромицин капс., 250 мг, 6 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-4u2s2whwed8/toggleWishlist":{"skuId":"226178391","productId":1434054447,"offerId":"dbKT67w1MXmTdVGaIqWkKQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpqD5wvje0rp1EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIr97nqwUQ1+rsaxiEqbIIIPfcwQc=","sign":"buZUeAtZOGUzeMMN7JLPhiJCQej/jaXDWi9JcdrFPEc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-4u2s2whwed8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Азитромицин капс., 250 мг, 6 шт.

    Рейтинг товара: 5 из 5
    на основе 14 оценок
    Цена 94 ₽
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  • Цифран таб. п/о плен., 250 мг, 10 шт.
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    Цифран таб. п/о плен., 250 мг, 10 шт.

    Рейтинг товара: 4.7 из 5
    на основе 6 оценок
    Цена 48 ₽
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  • Амоксиклав таб. п/о плен., 875 мг+125 мг, 14 шт.
    –19 %
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    Амоксиклав таб. п/о плен., 875 мг+125 мг, 14 шт.

    Рейтинг товара: 5 из 5
    на основе 43 оценки
    Цена 500 ₽ вместо 620
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  • Сумамед таб. п/о плен., 125 мг, 6 шт.
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    Сумамед таб. п/о плен., 125 мг, 6 шт.

    Рейтинг товара: 4.9 из 5
    на основе 33 оценки
    Цена 219 ₽
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  • Тетрациклин таб. п/о плен., 100 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6hl7eoh6vya/toggleWishlist":{"skuId":"661816045","productId":1778176336,"offerId":"wNF6OuDrsnaswkTHJSfZNg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpqD5wvje0rp1EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI0KLzzwYQ7YXKuwIY6NzQByD33MEH","sign":"0V2y7qReldTwa75wLmf+r1SRnvyZ2qM4TDtf/2F5mLg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6hl7eoh6vya/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тетрациклин таб. п/о плен., 100 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 14 оценок
    Цена 138 ₽
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  • Ципрофлоксацин Экоцифол таб. п/о плен., 500 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qrxf6gnhe79/toggleWishlist":{"skuId":"453489064","productId":1780859132,"offerId":"txVncBx1IfgYvclr4v6YnA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpqD5wvje0rp1EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI/IGX0QYQqOOe2AEY68v1ByD33MEH","sign":"Y3i461dPc5frEYJxlfT6gz9PrQRdfwgc83pu/GOv1aE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qrxf6gnhe79/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ципрофлоксацин Экоцифол таб. п/о плен., 500 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 9 оценок
    Цена 113 ₽
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  • Рокситромицин таб. п/о плен., 150 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-khw601es81/toggleWishlist":{"skuId":"186618039","productId":1778176874,"offerId":"dsJ0JoziqYiewU2zy9eDpA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpqD5wvje0rp1EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI6qbzzwYQt6H+WBiEqbIIIPfcwQc=","sign":"4Q7u3QqrZ1R+6Sv+z+eZdFBkEtvTgNVmS72jlY7FFsc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-khw601es81/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Рокситромицин таб. п/о плен., 150 мг, 10 шт.

    Рейтинг товара: 4.6 из 5
    на основе 22 оценки
    Цена 427 ₽
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Инструкция

Показания к применению

инфекционно-воспалительные заболевания, вызванные чувствительными микроорганизмами:
- заболевания нижних дыхательных путей (острый и хронический (в стадии обострения) бронхит, пневмония, бронхоэктатическая болезнь, инфекционные осложнения муковисцидоза);
- инфекции ЛОР-органов (острый синусит);
- инфекции почек и мочевыводящих путей (цистит, пиелонефрит);
- осложненные интраабдоминальные инфекции (в комбинации с метронидазолом);
- хронический бактериальный простатит;
- неосложненная гонорея;
- брюшной тиф,
- инфекционная диарея, в том числе кампилобактериоз, шигеллез, диарея “путешественников”;
- инфекции кожи и мягких тканей (инфицированные язвы, раны, ожоги, абсцессы, флегмона);
- костей и суставов (остеомиелит, септический артрит);
- инфекции на фоне иммунодефицита (возникающего при лечении иммунодепрессивными лекарственными средствами или у больных с нейтропенией);
- профилактика и лечение легочной формы сибирской язвы.
Дети.
- терапия осложнений, вызванных Pseudomonas aeruginosa у детей с муковисцидозом легких от 5 до 17 лет;
- профилактика и лечение легочной формы сибирской язвы (инфицирование Bacillus anthracis).

Противопоказания

-гиперчувствительность; -одновременный прием с тизанидином (риск выраженного снижения артериального давления, сонливости); -возраст до 18 лет (до завершения процесса формирования скелета, кроме терапии осложнений, вызванных Pseudomonas aeruginosa у детей с муковисцидозом легких от 5 до 17 лет; -профилактики и лечения легочной формы сибирской язвы), беременность, период лактации.

Способ применения и дозы

Внутрь. Таблетки следует проглатывать целиком с небольшим количеством жидкости после еды. При приеме таблетки натощак активное вещество всасывается быстрее.
При инфекциях нижних дыхательных путей легкой и средней степени - 0.5 г 2 раза в сутки, при тяжелом течении - 0.75 г 2 раза. Курс лечения - 7-14 дней.
При остром синусите - по 0.5 г 2 раза в сутки. Курс лечения - 10 дней.
При инфекции кожи и мягких тканей легкой и средней степени - 0.5 г 2 раза в сутки, при тяжелом течении-0.75 г 2 раза. Курс лечения - 7-14 дней.
При инфекциях костей и суставов - легкой и средней степени - 0.5 г2 раза в сутки, при тяжелом течении -0.75 г 2 раза. Курс лечения - до 4-6 нед.
При инфекциях мочевыводящих путей - по 0.25-0.5 г 2 раза в сутки; курс лечения - 7-14 дней, при неосложненном цистите у женщин - 3 дня.
При хроническом бактериальном простатите - по 0.5 г 2 раза, курс лечения - 28 дней.
При неосложненной гонорее - 0.25-0.5 г однократно.
Инфекционная диарея - по 0.5 г 2 раза, курс лечения - 5-7 дней. При брюшном тифе - по 0.5 г 2 раза; курс лечения - 10 дней.
При осложненных интраабдоминальных инфекциях - по 0.5 г каждые 12 ч в течение 7-14 дней.
Для профилактики и лечения легочной формы сибирской язвы - по 0.5 г 2 раза в сутки в течение 60 дней.
Другие инфекции (см. "Показания к применению") - по 0.5 г 2 раза в сутки.
В педиатрии
при лечении осложнений, вызванных Pseudomonas aeruginosa, у детей с муковисцидозом легких от 5 до 17 лет - 20 мг/кг 2 раза в сутки (максимальная доза 1.5 г).
Продолжительность лечения - 10-14 дней.
При легочной форме сибирской язвы (профилактика и лечение) - 15 мг/кг2 раза вдень.
Максимальная разовая доза - 0.5 г, суточная - 1г. Общая продолжительность приема ципрофлоксацина - 60 дней.
Хроническая почечная недостаточность: при КК более 50 мл/мин коррекции дозы не требуется; при КК 30-50 мл/мин - 0.25-0.5 каждые 12 ч; при КК 5-29 мл/мин - 0.25-0.5 г каждые 18 ч. Если больному проводится гемодиализ или перитонеальный диализ - 0.25-0.5 г/сут, но принимать препарат следует после сеанса гемодиализа.
Полная инструкция
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Ципрофлоксацин таб. п/о плен.
Ципрофлоксацин таб. п/о плен., 500 мг, 10 шт.
4.9
(20)
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10 вопросов
Инструкция

77 ₽

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4.9
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У продавца:20 оценок·3 отзыва
У всех продавцов:151 оценка·49 отзывов
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user avatar
4 месяца назад • Настасья • Куплен на Маркете
Комментарий: особых изменений в своем состоянии не обнаружила, поэтому ни плюсов, ни минусов нет
user avatar
Месяц назад • Vit pr • Куплен на Маркете
Достоинства: цена
Комментарий: быстро помогает, улучшает самочувствие..
user avatar
6 месяцев назад • Милли - Ванилли • Куплен на Маркете
Комментарий: Довольна. Спасибо.
Посмотреть все отзывы на Маркете
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