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Описание

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Лозартан-Тева таб. п/о плен., 25 мг, 30 шт.

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5.0
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Коротко о товаре

Артикул Маркета
4453151376
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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тяжелая печеночная недостаточность (более 9 баллов по шкале Чайлд-Пью); одновременное применение с алискиреном или алискиренсодержащими препаратами у пациентов с сахарным диабетом и/или нарушением функции почек (скорость клубочковой фильтрации менее 60 мл/мин/1,73 м ), возраст до 18 лет; наследственная непереносимость галактозы, дефицит лактазы или синдром мальабсорбции глюкозы-галактозы; беременность и период лактации.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EАртериальная гипотензия, сниженный объем циркулирующей крови (ОЦК), нарушения водно-электролитного баланса, двусторонний стеноз почечных артерий или стеноз артерии единственной почки, почечная недостаточность, состояние после трансплантации почки, печеночная недостаточность (менее 9 баллов но шкале Чайлд-Пью), аортальный и митральный стеноз, гипертрофическая обструктивная кардиомиопатия, сердечная недостаточность с сопутствующим тяжелым нарушением функции почек, тяжелая хроническая сердечная недостаточность IV функционального класса но классификации NYHA, сердечная недостаточность с угрожающими жизни аритмиями, ишемическая болезнь сердца, цереброваскулярные заболевания, первичный гиперальдостеронизм, ангионевротический отек в анамнезе.\u003Cbr\u003E"},{"name":"Состав","value":"На 1 таблетку: В 1 таблетке содержится: активное вещество: лозартан калия 25 мг/ 50 мг/ 100 мг; вспомогательные вещества: лактозы моногидрат 4,50 мг/ 9,00 мг/ 18,00 мг; целлюлоза микрокристаллическая 39.50 мг/ 79,00 мг/ 158.00 мг; крахмал прежелатинизироваыный 30,25 мг/ 60,50 мг/ 121.00 мг; магния стеарат 0,75 мг/ 1,50 мг/ 3,00 мг; Оболочка Opacity 1185F 18422 white: поливиниловый спирт (частично гидролизованный) 1,200 мг/ 2,400 мг/ 4,800 мг; титана диоксид (Е 171) 0,750 мг/ 1,500 мг/ 3,000 мг; макрогол 0,606 мг/ 1,212 мг/ 2,424 мг; тальк 0,444 мг/ 0.888 мг/ 1,776 мг."},{"name":"Действующее вещество","value":"Лозартан","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28710554"]}}},{"name":"Способ применения и дозы","value":"Препарат Лозартан-Тева принимают внутрь независимо от приема пищи. Таблетки проглатывают, не разжевывая, запивая водой. Кратность приема - 1 раз в сутки. \u003Cbr\u003EАртериальная гипертензия\u003Cbr\u003EПри артериальной гипертензии средняя суточная доза составляет 50 мг 1 раз/сут.\u003Cbr\u003EДля достижения большего терапевтического эффекта дозу увеличивают до 100 мг 1 раз в сутки.\u003Cbr\u003EХроническая сердечная недостаточность\u003Cbr\u003EНачальная доза для пациентов с хронической сердечной недостаточностью составляет 12,5 мг (1/2 таблетки по 25 мг) 1 раз в сутки. Как правило, доза увеличивается с недельным интервалом (то есть 12,5 (1/2 таблетки по 25 мг), мг/сутки, 25 мг/сутки и 50 мг/сутки) до средней поддерживающей дозы 50 мг 1 раз в сутки, в зависимости от переносимости препарата пациентом. Не требуется коррекции дозы препарата у пациентов пожилого возраста.\u003Cbr\u003EСнижение риска развития сердечно-сосудистых заболеваний (в том числе инсульта) и смертности у пациентов с артериальной гипертензией и гипертрофией левого желудочка\u003Cbr\u003EНачальная доза препарата составляет 50 мг 1 раз/сут. В дальнейшем может быть добавлен гидрохлоротиазид в низких дозах или увеличена доза препарата Лозартан-Тева до 100 мг в один или два приема с учетом снижения артериального давления (АД).\u003Cbr\u003EПациентам с сопутствующим сахарным диабетом 2 типа с протеинурией: препарат Лозарган-Тева назначают в начальной дозе - 50 мг 1 раз в сутки с дальнейшим повышением дозы до 100 мг/сутки (с учетом степени снижения АД) в один или в два приема.\u003Cbr\u003EУ пациентов со сниженным ОЦК (например, при приеме диуретиков в высоких дозах) рекомендуемая начальная доза препарата Лозартан-Тева составляет 25 мг 1 раз/сут. \u003Cbr\u003EПациентам с печеночной недостаточностью (менее 9 баллов по шкале Чайлд-Пью), при проведении процедуры гемодиализа, а также пациентам старше 75 лет рекомендуется более низкая начальная доза препарата - 25 мг 1 раз в сутки.\u003Cbr\u003EБезопасность и эффективность препарата у детей до 18 лет не установлена.\u003Cbr\u003EНедостаточно опыта применения препарата у пациентов с тяжелой печеночной недостаточностью, поэтому препарат не рекомендован у данной категории больных."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: головокружение, ортостатическая гипотензия.\u003Cbr\u003EСо стороны обмена веществ: гиперкалиемия.\u003Cbr\u003EАллергические реакции: ангионевротический отек (включая отеки лица, губ, глотки и/или языка), крапивница.\u003Cbr\u003EСо стороны пищеварительной системы: диарея, повышение активности АЛТ.\u003Cbr\u003EСо стороны ЦНС: головная боль.\u003Cbr\u003EДерматологические реакции: зуд.\u003Cbr\u003EПрочие: нарушения функции почек, миалгии."},{"name":"Фармакологическое действие","value":"Лозартан является специфическим антагонистом рецепторов ангиотензина II (подтип АТ1) для приема внутрь. Ангиотензин II избирательно связывается с АТ1-рецепторами, находящимися во многих тканях (в гладкомышечных тканях сосудов, надпочечниках, почках и сердце) и выполняет несколько важных биологических функций, включая вазоконстрикцию и высвобождение альдостерона. Ангиотензин II также стимулирует разрастание гладкомышечных клеток."},{"name":"Фармакологическая группа","value":"антагонисты рецепторов ангиотензина II (AT1-подтип)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Пол","value":"для женщин, для мужчин"},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25° С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: выраженное снижение АД и тахикардия; брадикардия может возникнуть вследствие парасимпатической стимуляции. Лечение: форсированный диурез, симптоматическая терапия; гемодиализ не эффективен."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Лозартан-Тева при беременности противопоказано. Применение лекарственных средств, воздействующих на РААС (ренин-ангиотензин-альдостероную систему), во втором и третьем триместре беременности снижает функцию почек и увеличивает заболеваемость и смертность плода и новорожденных. Развитие олигогидрамниона может быть ассоциировано с гипоплазией легких плода и деформациями костей скелета. Возможные нежелательные явления у новорожденных включают гипоплазию костей черепа, анурию, артериальную гипотензию, почечную недостаточность и летальный исход. При диагностировании беременности препарат должен быть сразу отменен. Указанные выше нежелательные исходы обычно обусловлены применением лекарственных средств, воздействующих на РААС, во втором и третьем триместре беременности. Большинство эпидемиологических исследований по изучению развития аномалий плода после применения гипотензивных средств в первом триместре беременности нс выявили различий между лекарственными средствами, воздействующими на РААС, и другими гипотензивными средствами. При назначении гипотензивной терапии беременным важно оптимизировать возможные исходы для матери и плода. В случае если невозможно подобрать альтернативную терапию взамен терапии лекарственными средствами, воздействующими на РААС, необходимо проинформировать пациентку о возможном риске терапии для плода. Необходимо проведение периодических ультразвуковых исследований с целью оценки интраамниотического пространства. В зависимости от недели беременности необходимо проведение соответствующих тестов плода. Неизвестно, выделяется ли лозартан с грудным молоком. Не рекомендуется принимать препарат Лозартан-Тева в период лактации. Если прием препарата Лозартан-Тева необходим в период лактации, то грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Не проводилось специальных клинических исследований по оценке влияния препарата на способность управлять транспортными средствами и работать с техникой. Следует иметь в виду возможность появления сонливости и головокружения, поэтому необходимо соблюдать осторожность при выполнении работ, требующих повышенного внимания, особенно в начале лечения, при повышении дозы препарата и при управлении транспортными средствами."},{"name":"Особые указания","value":"До начала применения препарата Лозартан-Тева необходимо проводить коррекцию ОЦК или начинать лечение с применения препарата в более низкой дозе. \u003Cbr\u003EГиперчувствительность\u003Cbr\u003EПациенты с ангионевротическим отеком в анамнезе (отек лица, губ, глотки и/или языка) должны находиться под строгим наблюдением.\u003Cbr\u003EПрепараты, оказывающие воздействие на РААС, могут увеличивать концентрацию мочевины в крови и концентрацию сывороточного креатинина у пациентов с двусторонним стенозом почечных артерий или стенозом артерии единственной почки.\u003Cbr\u003EВ период лечения следует регулярно контролировать содержание калия в крови, особенно у пациентов пожилого возраста, при нарушении функции почек.\u003Cbr\u003EИшемическая болезнь сердца (ИБС) и цереброваскулярные заболевания \u003Cbr\u003EКак при применении любых гипотензивных препаратов, слишком резкое снижение артериального давления у пациентов с ИБС и цереброваскулярными заболеваниями может привести к инфаркту миокарда или ишемическому инсульту.\u003Cbr\u003EПересадка почки\u003Cbr\u003EДанные о применении лозартана у пациентов, недавно перенесших пересадку почки, отсутствуют.\u003Cbr\u003EСтеноз аортального и митрального клапана, гипертрофическая обструктивная кардиомиопатия\u003Cbr\u003EПри применении препарата Лозартан-Тева. как и других вазодилататоров, у пациентов с гипертрофической обструктивной кардиомиопатией или гемодинамически значимым стенозом аортального или митрального клапана следует соблюдать осторожность. \u003Cbr\u003EСердечная недостаточность\u003Cbr\u003EУ пациентов с сердечной недостаточностью с нарушением функции почек или без нее, как при применении других лекарственных препаратов, действующих на РААС, существует риск развития тяжелой артериальной гипотензии и ос трой почечной недостаточности.\u003Cbr\u003EОпыта применения лозартана при лечении пациентов с сердечной недостаточностью и сопутствующей тяжелой почечной недостаточностью, у пациентов с тяжелой хронической сердечной недостаточностью (IV функционального класса по классификации NYHA), а также у пациентов с сердечной недостаточностью и угрожающими жизни аритмиями, практически нет. С учетом этого, при назначении препарата Лозартан-Тева данным категориям пациентов следует соблюдать осторожность.\u003Cbr\u003EПервичный гиперальдостеронизм\u003Cbr\u003EПациенты с первичным гиперальдостеронизмом обычно резистентны к терапии гипотензивными препаратами, влияющими на РАЛС. В связи с этим препарат Лозартан-Тева не рекомендуется назначать таким пациентам."},{"name":"Взаимодействие","value":"Двойная блокада РААС с применением антагонистов рецепторов ангиотензина II (АРА II), ингибиторов АПФ или алискирена (прямой ингибитор ренина) может сопровождаться повышенным риском развития артериальной гипотензии, обморока, гиперкалиемии и нарушений функции почек (в том числе острой почечной недостаточности) по сравнению с монотерапией. Необходим регулярный контроль АД, функции ночек и содержания электролитов в крови у пациентов, принимающих одновременно лозартан и другие лекарственные средства, влияющие на РААС.\u003Cbr\u003EЛозартан не должен применяться одновременно с алискиреном или алискиренсодержащими препаратами у пациентов с сахарным диабетом и/или с нарушением функции почек (скорость клубочковой фильтрации менее 60 мл/мип/1,73 м2). Применение препарата Лозартап-Тева в сочетании с иАПФ противопоказано пациентам с диабетической нефропатией и не рекомендован прочим пациентам. Может применяться одновременно с другими гипотензивными средствами.\u003Cbr\u003EВзаимно усиливает эффект бета-адреноблокаторов и симпатолитиков.\u003Cbr\u003EСовместное применение лозартана с диуретиками вызывает аддитивный эффект.\u003Cbr\u003EНе отмечено фармакокинетических взаимодействий лозартана с гидрохлоротиазидом, дигоксипом, варфарином, циметидином, фенобарбиталом, кетоконазолом и эритромицином. По сообщениям, рифампицин и флуконазол снижают концентрацию активного метаболита в плазме крови. Клиническое значение этих взаимодействий пока неизвестно.\u003Cbr\u003EКак и при применении других средств, ингибирующих ангиотензин II или его действие, совместное применение лозартана с калийсберегающими диуретиками (например, спиронолактоном, эплеренон (производное спиронолактона), триамтереном, амилоридом), препаратами калия, солями, содержащими калий, повышает риск гиперкалиемии. Нестероидные противовоспалительные препараты (ППВП), включая селективные ингибиторы пиклооксигеназы-2 (ЦОГ-2), могут снижать эффект диуретиков и других гипотензивных средств.\u003Cbr\u003EПри совместном применении антагонистов рецепторов ангиотензина II и лития возможно увеличение концентрации лития в плазме крови. Учитывая это, необходимо взвешивать пользу и риск совместного применения лозартана с солями лития. В случае необходимости совместного применения препаратов, надо регулярно контролировать концентрацию лития в плазме крови."},{"name":"Регистрационный номер","value":"ЛП-000090"},{"name":"Дата государственной регистрации","value":"07.06.2021"},{"name":"Владелец регистрационного удостоверения","value":"TEVA","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:14909142"]}}},{"name":"Страна бренда","value":"Израиль"},{"name":"Страна-производитель","value":"Венгрия"},{"name":"Название препарата","value":"Лозартан","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:17998824"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"14972997461921549514":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия, диабетическая нефропатия, профилактика сердечно-сосудистых заболеваний, хроническая сердечная недостаточность"},{"name":"Показания к применению","value":"-Артериальная гипертензия;\u003Cbr\u003E- хроническая сердечная недостаточность (в составе комбинированной терапии, при непереносимости или неэффективности терапии ингибиторами ЛПФ);\u003Cbr\u003E- снижение риска развития сердечно-сосудистых заболеваний (в том числе инсульта) и смертности у пациентов с артериальной гипертензией и гипертрофией левого желудочка;\u003Cbr\u003E- диабетическая нефропатия или гиперкреатипинемия и протеинурия (соотношение альбумина мочи и креатинина более 300 мг/сутки) у пациентов с сахарным диабетом 2 типа и сопутствующей артериальной гипертензией (снижение прогрессирования диабетической нефропатии до терминальной хронической почечной недостаточности)."},{"name":"Противопоказания","value":"Повышенная чувствительность к компонентам препарата; тяжелая печеночная недостаточность (более 9 баллов по шкале Чайлд-Пью); одновременное применение с алискиреном или алискиренсодержащими препаратами у пациентов с сахарным диабетом и/или нарушением функции почек (скорость клубочковой фильтрации менее 60 мл/мин/1,73 м ), возраст до 18 лет; наследственная непереносимость галактозы, дефицит лактазы или синдром мальабсорбции глюкозы-галактозы; беременность и период лактации.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EАртериальная гипотензия, сниженный объем циркулирующей крови (ОЦК), нарушения водно-электролитного баланса, двусторонний стеноз почечных артерий или стеноз артерии единственной почки, почечная недостаточность, состояние после трансплантации почки, печеночная недостаточность (менее 9 баллов но шкале Чайлд-Пью), аортальный и митральный стеноз, гипертрофическая обструктивная кардиомиопатия, сердечная недостаточность с сопутствующим тяжелым нарушением функции почек, тяжелая хроническая сердечная недостаточность IV функционального класса но классификации NYHA, сердечная недостаточность с угрожающими жизни аритмиями, ишемическая болезнь сердца, цереброваскулярные заболевания, первичный гиперальдостеронизм, ангионевротический отек в анамнезе.\u003Cbr\u003E"},{"name":"Состав","value":"На 1 таблетку: В 1 таблетке содержится: активное вещество: лозартан калия 25 мг/ 50 мг/ 100 мг; вспомогательные вещества: лактозы моногидрат 4,50 мг/ 9,00 мг/ 18,00 мг; целлюлоза микрокристаллическая 39.50 мг/ 79,00 мг/ 158.00 мг; крахмал прежелатинизироваыный 30,25 мг/ 60,50 мг/ 121.00 мг; магния стеарат 0,75 мг/ 1,50 мг/ 3,00 мг; Оболочка Opacity 1185F 18422 white: поливиниловый спирт (частично гидролизованный) 1,200 мг/ 2,400 мг/ 4,800 мг; титана диоксид (Е 171) 0,750 мг/ 1,500 мг/ 3,000 мг; макрогол 0,606 мг/ 1,212 мг/ 2,424 мг; тальк 0,444 мг/ 0.888 мг/ 1,776 мг."},{"name":"Действующее вещество","value":"Лозартан"},{"name":"Способ применения и дозы","value":"Препарат Лозартан-Тева принимают внутрь независимо от приема пищи. Таблетки проглатывают, не разжевывая, запивая водой. Кратность приема - 1 раз в сутки. \u003Cbr\u003EАртериальная гипертензия\u003Cbr\u003EПри артериальной гипертензии средняя суточная доза составляет 50 мг 1 раз/сут.\u003Cbr\u003EДля достижения большего терапевтического эффекта дозу увеличивают до 100 мг 1 раз в сутки.\u003Cbr\u003EХроническая сердечная недостаточность\u003Cbr\u003EНачальная доза для пациентов с хронической сердечной недостаточностью составляет 12,5 мг (1/2 таблетки по 25 мг) 1 раз в сутки. Как правило, доза увеличивается с недельным интервалом (то есть 12,5 (1/2 таблетки по 25 мг), мг/сутки, 25 мг/сутки и 50 мг/сутки) до средней поддерживающей дозы 50 мг 1 раз в сутки, в зависимости от переносимости препарата пациентом. Не требуется коррекции дозы препарата у пациентов пожилого возраста.\u003Cbr\u003EСнижение риска развития сердечно-сосудистых заболеваний (в том числе инсульта) и смертности у пациентов с артериальной гипертензией и гипертрофией левого желудочка\u003Cbr\u003EНачальная доза препарата составляет 50 мг 1 раз/сут. В дальнейшем может быть добавлен гидрохлоротиазид в низких дозах или увеличена доза препарата Лозартан-Тева до 100 мг в один или два приема с учетом снижения артериального давления (АД).\u003Cbr\u003EПациентам с сопутствующим сахарным диабетом 2 типа с протеинурией: препарат Лозарган-Тева назначают в начальной дозе - 50 мг 1 раз в сутки с дальнейшим повышением дозы до 100 мг/сутки (с учетом степени снижения АД) в один или в два приема.\u003Cbr\u003EУ пациентов со сниженным ОЦК (например, при приеме диуретиков в высоких дозах) рекомендуемая начальная доза препарата Лозартан-Тева составляет 25 мг 1 раз/сут. \u003Cbr\u003EПациентам с печеночной недостаточностью (менее 9 баллов по шкале Чайлд-Пью), при проведении процедуры гемодиализа, а также пациентам старше 75 лет рекомендуется более низкая начальная доза препарата - 25 мг 1 раз в сутки.\u003Cbr\u003EБезопасность и эффективность препарата у детей до 18 лет не установлена.\u003Cbr\u003EНедостаточно опыта применения препарата у пациентов с тяжелой печеночной недостаточностью, поэтому препарат не рекомендован у данной категории больных."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: головокружение, ортостатическая гипотензия.\u003Cbr\u003EСо стороны обмена веществ: гиперкалиемия.\u003Cbr\u003EАллергические реакции: ангионевротический отек (включая отеки лица, губ, глотки и/или языка), крапивница.\u003Cbr\u003EСо стороны пищеварительной системы: диарея, повышение активности АЛТ.\u003Cbr\u003EСо стороны ЦНС: головная боль.\u003Cbr\u003EДерматологические реакции: зуд.\u003Cbr\u003EПрочие: нарушения функции почек, миалгии."},{"name":"Фармакологическое действие","value":"Лозартан является специфическим антагонистом рецепторов ангиотензина II (подтип АТ1) для приема внутрь. Ангиотензин II избирательно связывается с АТ1-рецепторами, находящимися во многих тканях (в гладкомышечных тканях сосудов, надпочечниках, почках и сердце) и выполняет несколько важных биологических функций, включая вазоконстрикцию и высвобождение альдостерона. Ангиотензин II также стимулирует разрастание гладкомышечных клеток."},{"name":"Фармакологическая группа","value":"антагонисты рецепторов ангиотензина II (AT1-подтип)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Пол","value":"для женщин, для мужчин"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25° С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: выраженное снижение АД и тахикардия; брадикардия может возникнуть вследствие парасимпатической стимуляции. Лечение: форсированный диурез, симптоматическая терапия; гемодиализ не эффективен."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Лозартан-Тева при беременности противопоказано. Применение лекарственных средств, воздействующих на РААС (ренин-ангиотензин-альдостероную систему), во втором и третьем триместре беременности снижает функцию почек и увеличивает заболеваемость и смертность плода и новорожденных. Развитие олигогидрамниона может быть ассоциировано с гипоплазией легких плода и деформациями костей скелета. Возможные нежелательные явления у новорожденных включают гипоплазию костей черепа, анурию, артериальную гипотензию, почечную недостаточность и летальный исход. При диагностировании беременности препарат должен быть сразу отменен. Указанные выше нежелательные исходы обычно обусловлены применением лекарственных средств, воздействующих на РААС, во втором и третьем триместре беременности. Большинство эпидемиологических исследований по изучению развития аномалий плода после применения гипотензивных средств в первом триместре беременности нс выявили различий между лекарственными средствами, воздействующими на РААС, и другими гипотензивными средствами. При назначении гипотензивной терапии беременным важно оптимизировать возможные исходы для матери и плода. В случае если невозможно подобрать альтернативную терапию взамен терапии лекарственными средствами, воздействующими на РААС, необходимо проинформировать пациентку о возможном риске терапии для плода. Необходимо проведение периодических ультразвуковых исследований с целью оценки интраамниотического пространства. В зависимости от недели беременности необходимо проведение соответствующих тестов плода. Неизвестно, выделяется ли лозартан с грудным молоком. Не рекомендуется принимать препарат Лозартан-Тева в период лактации. Если прием препарата Лозартан-Тева необходим в период лактации, то грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Не проводилось специальных клинических исследований по оценке влияния препарата на способность управлять транспортными средствами и работать с техникой. Следует иметь в виду возможность появления сонливости и головокружения, поэтому необходимо соблюдать осторожность при выполнении работ, требующих повышенного внимания, особенно в начале лечения, при повышении дозы препарата и при управлении транспортными средствами."},{"name":"Особые указания","value":"До начала применения препарата Лозартан-Тева необходимо проводить коррекцию ОЦК или начинать лечение с применения препарата в более низкой дозе. \u003Cbr\u003EГиперчувствительность\u003Cbr\u003EПациенты с ангионевротическим отеком в анамнезе (отек лица, губ, глотки и/или языка) должны находиться под строгим наблюдением.\u003Cbr\u003EПрепараты, оказывающие воздействие на РААС, могут увеличивать концентрацию мочевины в крови и концентрацию сывороточного креатинина у пациентов с двусторонним стенозом почечных артерий или стенозом артерии единственной почки.\u003Cbr\u003EВ период лечения следует регулярно контролировать содержание калия в крови, особенно у пациентов пожилого возраста, при нарушении функции почек.\u003Cbr\u003EИшемическая болезнь сердца (ИБС) и цереброваскулярные заболевания \u003Cbr\u003EКак при применении любых гипотензивных препаратов, слишком резкое снижение артериального давления у пациентов с ИБС и цереброваскулярными заболеваниями может привести к инфаркту миокарда или ишемическому инсульту.\u003Cbr\u003EПересадка почки\u003Cbr\u003EДанные о применении лозартана у пациентов, недавно перенесших пересадку почки, отсутствуют.\u003Cbr\u003EСтеноз аортального и митрального клапана, гипертрофическая обструктивная кардиомиопатия\u003Cbr\u003EПри применении препарата Лозартан-Тева. как и других вазодилататоров, у пациентов с гипертрофической обструктивной кардиомиопатией или гемодинамически значимым стенозом аортального или митрального клапана следует соблюдать осторожность. \u003Cbr\u003EСердечная недостаточность\u003Cbr\u003EУ пациентов с сердечной недостаточностью с нарушением функции почек или без нее, как при применении других лекарственных препаратов, действующих на РААС, существует риск развития тяжелой артериальной гипотензии и ос трой почечной недостаточности.\u003Cbr\u003EОпыта применения лозартана при лечении пациентов с сердечной недостаточностью и сопутствующей тяжелой почечной недостаточностью, у пациентов с тяжелой хронической сердечной недостаточностью (IV функционального класса по классификации NYHA), а также у пациентов с сердечной недостаточностью и угрожающими жизни аритмиями, практически нет. С учетом этого, при назначении препарата Лозартан-Тева данным категориям пациентов следует соблюдать осторожность.\u003Cbr\u003EПервичный гиперальдостеронизм\u003Cbr\u003EПациенты с первичным гиперальдостеронизмом обычно резистентны к терапии гипотензивными препаратами, влияющими на РАЛС. В связи с этим препарат Лозартан-Тева не рекомендуется назначать таким пациентам."},{"name":"Взаимодействие","value":"Двойная блокада РААС с применением антагонистов рецепторов ангиотензина II (АРА II), ингибиторов АПФ или алискирена (прямой ингибитор ренина) может сопровождаться повышенным риском развития артериальной гипотензии, обморока, гиперкалиемии и нарушений функции почек (в том числе острой почечной недостаточности) по сравнению с монотерапией. Необходим регулярный контроль АД, функции ночек и содержания электролитов в крови у пациентов, принимающих одновременно лозартан и другие лекарственные средства, влияющие на РААС.\u003Cbr\u003EЛозартан не должен применяться одновременно с алискиреном или алискиренсодержащими препаратами у пациентов с сахарным диабетом и/или с нарушением функции почек (скорость клубочковой фильтрации менее 60 мл/мип/1,73 м2). Применение препарата Лозартап-Тева в сочетании с иАПФ противопоказано пациентам с диабетической нефропатией и не рекомендован прочим пациентам. Может применяться одновременно с другими гипотензивными средствами.\u003Cbr\u003EВзаимно усиливает эффект бета-адреноблокаторов и симпатолитиков.\u003Cbr\u003EСовместное применение лозартана с диуретиками вызывает аддитивный эффект.\u003Cbr\u003EНе отмечено фармакокинетических взаимодействий лозартана с гидрохлоротиазидом, дигоксипом, варфарином, циметидином, фенобарбиталом, кетоконазолом и эритромицином. По сообщениям, рифампицин и флуконазол снижают концентрацию активного метаболита в плазме крови. Клиническое значение этих взаимодействий пока неизвестно.\u003Cbr\u003EКак и при применении других средств, ингибирующих ангиотензин II или его действие, совместное применение лозартана с калийсберегающими диуретиками (например, спиронолактоном, эплеренон (производное спиронолактона), триамтереном, амилоридом), препаратами калия, солями, содержащими калий, повышает риск гиперкалиемии. Нестероидные противовоспалительные препараты (ППВП), включая селективные ингибиторы пиклооксигеназы-2 (ЦОГ-2), могут снижать эффект диуретиков и других гипотензивных средств.\u003Cbr\u003EПри совместном применении антагонистов рецепторов ангиотензина II и лития возможно увеличение концентрации лития в плазме крови. Учитывая это, необходимо взвешивать пользу и риск совместного применения лозартана с солями лития. В случае необходимости совместного применения препаратов, надо регулярно контролировать концентрацию лития в плазме крови."},{"name":"Регистрационный номер","value":"ЛП-000090"},{"name":"Дата государственной регистрации","value":"07.06.2021"},{"name":"Владелец регистрационного удостоверения","value":"TEVA"},{"name":"Страна бренда","value":"Израиль"},{"name":"Страна-производитель","value":"Венгрия"},{"name":"Название препарата","value":"Лозартан"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_7706439996522979423"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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    на основе 18 оценок
    Цена 122 ₽
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  • Лозартан-тева таб. п/о плен., 25 мг, 30 шт.
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    Лозартан-тева таб. п/о плен., 25 мг, 30 шт.

    Цена 106 ₽
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  • Лозартан таб. п/о плен., 50 мг, 90 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ydznorqsxe9/toggleWishlist":{"skuId":"453489075","productId":1401075757,"offerId":"TlRhkwuJRWuGdfUHmBVXOQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhtnogpmgv9xLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIrfCKnAUQs+Oe2AEYl7b7BSDX3MEH","sign":"DqU86FGI+coaSgC750D1Xnd23LaiIqmv4wiuqf2yu00="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ydznorqsxe9/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лозартан таб. п/о плен., 50 мг, 90 шт.

    Рейтинг товара: 4.9 из 5
    на основе 63 оценки
    Цена 338 ₽
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  • Лозартан Канон таб. п/о плен., 100 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-76cip89pyw6/toggleWishlist":{"skuId":"186540667","productId":1401075463,"offerId":"xjSBmFaVPOcMZ-2qpCNuPw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhtnogpmgv9xLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIh+6KnAUQ+8T5WBjOwtkHINfcwQc=","sign":"2r2lP/EWDoaRGk4ELKslHK9RgiHQTptpglwQizydSrY="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-76cip89pyw6/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лозартан Канон таб. п/о плен., 100 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 31 оценка
    Цена 155 ₽
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  • Лозартан Канон таб. п/о плен., 50 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-07s4q8ussk9h/toggleWishlist":{"skuId":"661011054","productId":1401075926,"offerId":"o-hScJrHB7UjGUhXuMZjNg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhtnogpmgv9xLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI1vGKnAUQ7vSYuwIYzsLZByDX3MEH","sign":"VPcHBySCIIkvgUnbQFZm2HtcnfGGT/51AvNbVNqz4LE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-07s4q8ussk9h/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лозартан Канон таб. п/о плен., 50 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 66 оценок
    Цена 173 ₽
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  • Периндоприл таб., 4 мг, 30 шт.
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    Периндоприл таб., 4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 72 оценки
    Цена 155 ₽
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  • Лозартан-Ксантис таб. п/о плен., 50 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mobw2d4dwzp/toggleWishlist":{"skuId":"101714278789","productId":1746279075,"offerId":"QlI7T8UcZFGuuJMlWeuI-g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhtnogpmgv9xLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIo7XYwAYQhfOS9foCGKr9hhEg19zBBw==","sign":"/FqwRUX7ss/OBeV1riwgNwyUttwvRupibC2ZkfL00ZE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mobw2d4dwzp/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лозартан-Ксантис таб. п/о плен., 50 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 13 оценок
    Цена 169 ₽
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  • Лозартан таб. п/о плен., 50 мг, 30 шт.
    –19 %
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    Лозартан таб. п/о плен., 50 мг, 30 шт.

    Рейтинг товара: 4.6 из 5
    на основе 10 оценок
    Цена 213 ₽ вместо 263
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  • Лозартан таб. п/о плен., 12.5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-15xabi4p7ef/toggleWishlist":{"skuId":"102793793732","productId":1780857914,"offerId":"CtKGK8pC89y5iVxXZJPYvQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhtnogpmgv9xLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIuviW0QYQxKHz9/4CGIyBzwYg19zBBw==","sign":"KqmSXJEfeEqFo1Cc9bCGyGsZ1FnFqMB6v0mplwNqUls="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-15xabi4p7ef/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лозартан таб. п/о плен., 12.5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 67 ₽
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  • Лозартан таб. п/о плен., 50 мг, 30 шт.
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    Лозартан таб. п/о плен., 50 мг, 30 шт.

    Цена 217 ₽
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  • Лозартан таб. п/о плен., 12.5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8ow6yy70olv/toggleWishlist":{"skuId":"227814268","productId":1401075610,"offerId":"iSeev86rxdAOhKHZqrpoQg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhtnogpmgv9xLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUImu+KnAUQ/NbQbBiEqbIIINfcwQc=","sign":"AD7vMqpEjPgI7pKroerroi40VATPoWqRzq20ep8tAbI="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8ow6yy70olv/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лозартан таб. п/о плен., 12.5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 12 оценок
    Цена 55 ₽
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Инструкция

Показания к применению

-Артериальная гипертензия;
- хроническая сердечная недостаточность (в составе комбинированной терапии, при непереносимости или неэффективности терапии ингибиторами ЛПФ);
- снижение риска развития сердечно-сосудистых заболеваний (в том числе инсульта) и смертности у пациентов с артериальной гипертензией и гипертрофией левого желудочка;
- диабетическая нефропатия или гиперкреатипинемия и протеинурия (соотношение альбумина мочи и креатинина более 300 мг/сутки) у пациентов с сахарным диабетом 2 типа и сопутствующей артериальной гипертензией (снижение прогрессирования диабетической нефропатии до терминальной хронической почечной недостаточности).

Противопоказания

Повышенная чувствительность к компонентам препарата; тяжелая печеночная недостаточность (более 9 баллов по шкале Чайлд-Пью); одновременное применение с алискиреном или алискиренсодержащими препаратами у пациентов с сахарным диабетом и/или нарушением функции почек (скорость клубочковой фильтрации менее 60 мл/мин/1,73 м ), возраст до 18 лет; наследственная непереносимость галактозы, дефицит лактазы или синдром мальабсорбции глюкозы-галактозы; беременность и период лактации.
С осторожностью:
Артериальная гипотензия, сниженный объем циркулирующей крови (ОЦК), нарушения водно-электролитного баланса, двусторонний стеноз почечных артерий или стеноз артерии единственной почки, почечная недостаточность, состояние после трансплантации почки, печеночная недостаточность (менее 9 баллов но шкале Чайлд-Пью), аортальный и митральный стеноз, гипертрофическая обструктивная кардиомиопатия, сердечная недостаточность с сопутствующим тяжелым нарушением функции почек, тяжелая хроническая сердечная недостаточность IV функционального класса но классификации NYHA, сердечная недостаточность с угрожающими жизни аритмиями, ишемическая болезнь сердца, цереброваскулярные заболевания, первичный гиперальдостеронизм, ангионевротический отек в анамнезе.

Способ применения и дозы

Препарат Лозартан-Тева принимают внутрь независимо от приема пищи. Таблетки проглатывают, не разжевывая, запивая водой. Кратность приема - 1 раз в сутки.
Артериальная гипертензия
При артериальной гипертензии средняя суточная доза составляет 50 мг 1 раз/сут.
Для достижения большего терапевтического эффекта дозу увеличивают до 100 мг 1 раз в сутки.
Хроническая сердечная недостаточность
Начальная доза для пациентов с хронической сердечной недостаточностью составляет 12,5 мг (1/2 таблетки по 25 мг) 1 раз в сутки. Как правило, доза увеличивается с недельным интервалом (то есть 12,5 (1/2 таблетки по 25 мг), мг/сутки, 25 мг/сутки и 50 мг/сутки) до средней поддерживающей дозы 50 мг 1 раз в сутки, в зависимости от переносимости препарата пациентом. Не требуется коррекции дозы препарата у пациентов пожилого возраста.
Снижение риска развития сердечно-сосудистых заболеваний (в том числе инсульта) и смертности у пациентов с артериальной гипертензией и гипертрофией левого желудочка
Начальная доза препарата составляет 50 мг 1 раз/сут. В дальнейшем может быть добавлен гидрохлоротиазид в низких дозах или увеличена доза препарата Лозартан-Тева до 100 мг в один или два приема с учетом снижения артериального давления (АД).
Пациентам с сопутствующим сахарным диабетом 2 типа с протеинурией: препарат Лозарган-Тева назначают в начальной дозе - 50 мг 1 раз в сутки с дальнейшим повышением дозы до 100 мг/сутки (с учетом степени снижения АД) в один или в два приема.
У пациентов со сниженным ОЦК (например, при приеме диуретиков в высоких дозах) рекомендуемая начальная доза препарата Лозартан-Тева составляет 25 мг 1 раз/сут.
Пациентам с печеночной недостаточностью (менее 9 баллов по шкале Чайлд-Пью), при проведении процедуры гемодиализа, а также пациентам старше 75 лет рекомендуется более низкая начальная доза препарата - 25 мг 1 раз в сутки.
Безопасность и эффективность препарата у детей до 18 лет не установлена.
Недостаточно опыта применения препарата у пациентов с тяжелой печеночной недостаточностью, поэтому препарат не рекомендован у данной категории больных.
Полная инструкция
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Лозартан-Тева таб. п/о плен.
Лозартан-Тева таб. п/о плен., 25 мг, 30 шт.
5.0
(1)
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2 вопроса
Инструкция

109 ₽

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