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Велсон таб. п/о плен., 3 мг, 30 шт.

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4.3
(16)
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Коротко о товаре

Артикул Маркета
3420516480
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 мин до сна.\u003Cbr\u003EПациенты с нарушением функции почек\u003Cbr\u003EВлияние различной степени почечной недостаточности на фармакокинетику мелатонина не изучено, поэтому мелатонин нужно принимать с осторожностью таким пациентам. Пациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"name":"Побочные действия","value":"Инфекционные и паразитарные заболевания: редко - опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: редко - лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: частота неизвестна - реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания: редко - гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушения психики: нечасто - раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога; редко - перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы: нечасто - мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость; редко - обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения: редко - снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: редко - вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердца: редко - стенокардия напряжения, ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны сосудов: нечасто - артериальная гипертензия; редко - \"приливы\".\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: нечасто - абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота; редко - гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: нечасто - гипербилирубинемия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: нечасто - дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи; редко - экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей; частота неизвестна - отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: нечасто - боль в конечностях; редко - артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: нечасто - глюкозурия, протеинурия; редко - полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и молочных желез: нечасто - менопаузальные симптомы; редко - приапизм, простатит; частота неизвестна - галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: нечасто - астения, боль в груди; редко - утомляемость, боль, жажда.\u003Cbr\u003EВлияние на результаты лабораторных и инструментальных исследований: нечасто - отклонение от нормы лабораторных показателей функции печени, увеличение массы тела; редко - повышение активности \"печеночных\" трансаминаз, отклонение от нормы содержания электролитов в крови, отклонение от нормы результатов лабораторных тестов.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Синтетический аналог гормона шишковидного тела (эпифиза); оказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы. Увеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина. Регулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу.\u003Cbr\u003EСпособствует организации биологического ритма и нормализации ночного сна. Улучшает качество сна, ускоряет засыпание, регулирует нейроэндокринные функции. Адаптирует организм метеочувствительных людей к изменениям погодных условий."},{"name":"Фармакологическая группа","value":"адаптогенное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозе до 300 мг не вызывало клинически значимых нежелательных реакций. Наблюдались гиперемия, спазмы в брюшной полости, диарея, головная боль и скотома при применении мелатонина в дозах 3000-6600 мг в течение нескольких недель. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания.\u003Cbr\u003EСимптомы: при передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение: промывание желудка, активированный уголь, симптоматическая терапия. Клиренс активного вещества предполагается в пределах 12 ч после приема внутрь."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Велсон противопоказан к применению при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Велсон вызывает сонливость, в связи с этим в период лечения следует воздержаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"В период применения препарата Велсон рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у пациентов с аутоиммунными заболеваниями, в связи с чем, применение у данной категории пациентов не рекомендуется. \u003Cbr\u003EПрепарат Велсон нужно применять с осторожностью пациентам с различной степенью почечной недостаточности."},{"name":"Взаимодействие","value":"Фармакокинетическое взаимодействие\u003Cbr\u003EИзвестно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003EВ концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A, по-видимому, незначимо.\u003Cbr\u003EМетаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1А.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина (увеличение AUC в 17 раз и Сmах в 12 раз) за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1А2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин (ингибитор изоферментов CYP2D), поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EКурение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1A1 и CYP1A2.\u003Cbr\u003EИнгибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003EИндукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003EВ современной литературе имеется множество данных, касающихся влияния агонистов/ антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003EВо время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003EМелатонин потенциирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплен, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003EВ ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют на центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"name":"Регистрационный номер","value":"ЛП-005391"},{"name":"Дата государственной регистрации","value":"11.06.2019"},{"name":"Владелец регистрационного удостоверения","value":"Petrovax","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:15266591"]}}},{"name":"Изготовитель","value":"Фармпроект"},{"name":"Фасовщик","value":"Фармпроект"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Велсон","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18038314"]}}},{"name":"Срок годности","value":"48 мес."}]}},"fullSpecsGrouped":{"17072139860723554968":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"нервная система"},{"name":"Назначение","value":"бессонница, десинхроноз, нарушение сна, нормализация сна"},{"name":"Показания к применению","value":"При расстройстве сна, в т.ч. обусловленных нарушением ритма \"сон-бодрствование\", таких как десинхроноз (резкая смена часовых поясов)."},{"name":"Противопоказания","value":"- Гиперчувствительность к компонентам препарата;\u003Cbr\u003E- аутоиммунные заболевания;\u003Cbr\u003E- печеночная недостаточность;\u003Cbr\u003E- тяжелая почечная недостаточность;\u003Cbr\u003E- беременность и период грудного вскармливания;\u003Cbr\u003E- возраст до 18 лет (эффективность и безопасность препарата не установлена).\u003Cbr\u003E"},{"name":"Состав","value":"Одна таблетка, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EДействующее вещество: мелатонин - 3 мг.\u003Cbr\u003EВспомогательные вещества: кальция гидрофосфат дигидрат - 64,67 мг, целлюлоза микрокристаллическая - 25,00 мг, повидон К 25 - 3,33 мг, кроскармеллоза натрия - 2,00 мг, тальк - 1,00 мг, кремния диоксид коллоидный - 0,50 мг, кальция стеарат - 0,50 мг.\u003Cbr\u003EСостав оболочки: опадрай белый (03А280002) - 3,00 мг [гипромеллоза (гидроксипропилметилцеллюлоза) - 40%, целлюлоза микрокристаллическая - 32%, титана диоксид - 20%, макрогол (полиэтиленгликоль) - 8%]."},{"name":"Действующее вещество","value":"Мелатонин"},{"name":"Способ применения и дозы","value":"Внутрь, запивая достаточным количеством жидкости.\u003Cbr\u003EПри нарушении сна: 3 мг 1 раз в день за 30-40 мин до сна.\u003Cbr\u003EПри десинхронозе в качестве адаптогена при смене часовых поясов: за 1 день до перелета и в последующие 2-5 дней по 3 мг за 30-40 мин до сна.\u003Cbr\u003EМаксимальная суточная доза - 6 мг.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EС возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пациентов пожилого возраста. С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 мин до сна.\u003Cbr\u003EПациенты с нарушением функции почек\u003Cbr\u003EВлияние различной степени почечной недостаточности на фармакокинетику мелатонина не изучено, поэтому мелатонин нужно принимать с осторожностью таким пациентам. Пациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"name":"Побочные действия","value":"Инфекционные и паразитарные заболевания: редко - опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: редко - лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: частота неизвестна - реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания: редко - гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушения психики: нечасто - раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога; редко - перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы: нечасто - мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость; редко - обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения: редко - снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: редко - вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердца: редко - стенокардия напряжения, ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны сосудов: нечасто - артериальная гипертензия; редко - \"приливы\".\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: нечасто - абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота; редко - гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: нечасто - гипербилирубинемия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: нечасто - дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи; редко - экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей; частота неизвестна - отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: нечасто - боль в конечностях; редко - артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: нечасто - глюкозурия, протеинурия; редко - полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и молочных желез: нечасто - менопаузальные симптомы; редко - приапизм, простатит; частота неизвестна - галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: нечасто - астения, боль в груди; редко - утомляемость, боль, жажда.\u003Cbr\u003EВлияние на результаты лабораторных и инструментальных исследований: нечасто - отклонение от нормы лабораторных показателей функции печени, увеличение массы тела; редко - повышение активности \"печеночных\" трансаминаз, отклонение от нормы содержания электролитов в крови, отклонение от нормы результатов лабораторных тестов.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Синтетический аналог гормона шишковидного тела (эпифиза); оказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы. Увеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина. Регулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу.\u003Cbr\u003EСпособствует организации биологического ритма и нормализации ночного сна. Улучшает качество сна, ускоряет засыпание, регулирует нейроэндокринные функции. Адаптирует организм метеочувствительных людей к изменениям погодных условий."},{"name":"Фармакологическая группа","value":"адаптогенное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозе до 300 мг не вызывало клинически значимых нежелательных реакций. Наблюдались гиперемия, спазмы в брюшной полости, диарея, головная боль и скотома при применении мелатонина в дозах 3000-6600 мг в течение нескольких недель. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания.\u003Cbr\u003EСимптомы: при передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение: промывание желудка, активированный уголь, симптоматическая терапия. Клиренс активного вещества предполагается в пределах 12 ч после приема внутрь."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Велсон противопоказан к применению при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Велсон вызывает сонливость, в связи с этим в период лечения следует воздержаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"В период применения препарата Велсон рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у пациентов с аутоиммунными заболеваниями, в связи с чем, применение у данной категории пациентов не рекомендуется. \u003Cbr\u003EПрепарат Велсон нужно применять с осторожностью пациентам с различной степенью почечной недостаточности."},{"name":"Взаимодействие","value":"Фармакокинетическое взаимодействие\u003Cbr\u003EИзвестно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003EВ концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A, по-видимому, незначимо.\u003Cbr\u003EМетаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1А.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина (увеличение AUC в 17 раз и Сmах в 12 раз) за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1А2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин (ингибитор изоферментов CYP2D), поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EКурение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1A1 и CYP1A2.\u003Cbr\u003EИнгибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003EИндукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003EВ современной литературе имеется множество данных, касающихся влияния агонистов/ антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003EВо время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003EМелатонин потенциирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплен, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003EВ ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют на центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"name":"Регистрационный номер","value":"ЛП-005391"},{"name":"Дата государственной регистрации","value":"11.06.2019"},{"name":"Владелец регистрационного удостоверения","value":"Petrovax"},{"name":"Изготовитель","value":"Фармпроект"},{"name":"Фасовщик","value":"Фармпроект"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Велсон"},{"name":"Срок годности","value":"48 мес."}]}],"transitionId":"tr_17853475051002165019"}}}}
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622 ₽

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  • 11-13 июня, самовывоз • 0 ₽
POLZAru
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  • Гармония сна капс., 0.36 г
    –54 %
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    Гармония сна капс., 0.36 г

    Рейтинг товара: 4.4 из 5
    на основе 57 оценок
    Цена 341 ₽ вместо 742
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  • Сонные+ таб., 30 шт., 1 уп.
    –31 %
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    Сонные+ таб., 30 шт., 1 уп.

    Рейтинг товара: 4.1 из 5
    на основе 148 оценок
    Цена 275 ₽ вместо 399
    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таб., 30 шт., 1 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  • Формула сна экспресс таб. д/рассас., 40 шт.
    –10 %
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    Формула сна экспресс таб. д/рассас., 40 шт.

    Рейтинг товара: 4.3 из 5
    на основе 78 оценок
    Цена 396 ₽ вместо 440
    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сна экспресс таб. д/рассас., 40 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  • Мелаксен таб., 3 мг, 24 шт.
    –1 %
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    Мелаксен таб., 3 мг, 24 шт.

    Рейтинг товара: 4.8 из 5
    на основе 174 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 722 ₽ вместо 729
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  • Мелатонин-СЗ таб. п/о плен., 3 мг, 30 шт., 1 уп.
    –1 %
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    Мелатонин-СЗ таб. п/о плен., 3 мг, 30 шт., 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 24 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 336 ₽ вместо 339
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  • Соннован таб. п/о плен., 3 мг, 30 шт.
    –1 %
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    Соннован таб. п/о плен., 3 мг, 30 шт.

    Рейтинг товара: 4.6 из 5
    на основе 15 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 397 ₽ вместо 401
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  • Донормил таб. п/о плен., 15 мг, 30 шт.
    –17 %
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    Донормил таб. п/о плен., 15 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 35 оценок
    Цена 516 ₽ вместо 619
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  • Формула сна таб., 40 шт., 1 уп.
    –20 %
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    Формула сна таб., 40 шт., 1 уп.

    Рейтинг товара: 4.3 из 5
    на основе 27 оценок
    Цена 371 ₽ вместо 464
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сна таб., 40 шт., 1 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  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
    –8 %
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 23 оценки
    Цена 550 ₽ вместо 600
    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Триптофан капс., 500 мг, 0.25 г, 90 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  • СонНорм Дуо таб. п/о плен., 20 шт.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-bonzyt1izcw/toggleWishlist":{"skuId":"101809292934","productId":1767864030,"offerId":"A33ED4WN-jGK5VUOZ-ztEQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ3fPdwYvW94QJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI3u39ygYQho26ovsCGI+83gcg7dnBBw==","sign":"FWA+zxNID/Oug3GtJcd57Zcue50Ad2s1RtlNZP0bVlg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-bonzyt1izcw/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    СонНорм Дуо таб. п/о плен., 20 шт.

    Рейтинг товара: 4.3 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 412 ₽ вместо 420
    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Дуо таб. п/о плен., 20 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  • Меларена таб. п/о плен., 3 мг, 30 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-edpehusbfxu/toggleWishlist":{"skuId":"228041550","productId":1778172750,"offerId":"VfZudrZP3dqCsSDieYyj7w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ3fPdwYvW94QJEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIzobzzwYQzsbebBjZ8c8GIO3ZwQc=","sign":"XdqJspaAsg0v+Mh3qGBjpHPkH1EyCukO8WEEdc+O2Ak="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-edpehusbfxu/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Меларена таб. п/о плен., 3 мг, 30 шт.

    Рейтинг товара: 4.4 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 516 ₽ вместо 521
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Инструкция

Показания к применению

При расстройстве сна, в т.ч. обусловленных нарушением ритма "сон-бодрствование", таких как десинхроноз (резкая смена часовых поясов).

Противопоказания

- Гиперчувствительность к компонентам препарата;
- аутоиммунные заболевания;
- печеночная недостаточность;
- тяжелая почечная недостаточность;
- беременность и период грудного вскармливания;
- возраст до 18 лет (эффективность и безопасность препарата не установлена).

Способ применения и дозы

Внутрь, запивая достаточным количеством жидкости.
При нарушении сна: 3 мг 1 раз в день за 30-40 мин до сна.
При десинхронозе в качестве адаптогена при смене часовых поясов: за 1 день до перелета и в последующие 2-5 дней по 3 мг за 30-40 мин до сна.
Максимальная суточная доза - 6 мг.
Пациенты пожилого возраста
С возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пациентов пожилого возраста. С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 мин до сна.
Пациенты с нарушением функции почек
Влияние различной степени почечной недостаточности на фармакокинетику мелатонина не изучено, поэтому мелатонин нужно принимать с осторожностью таким пациентам. Пациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется.
Полная инструкция
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Велсон таб. п/о плен.
Велсон таб. п/о плен., 3 мг, 30 шт.
4.3
(16)
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8 вопросов
Инструкция

622 ₽

Скидка: 21%
–21 %
Вместо:788 ₽
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4.3
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У продавца:16 оценок·8 отзывов
У всех продавцов:361 оценка·208 отзывов
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user avatar
Год назад • Антон • Куплен на Маркете
Достоинства: реально работающий компонент в составе, можно принимать с успокоительными, не снотворное.
Недостатки: работает но есть ньансы
Комментарий: Велсон реально работает когда нужно облегчить засыпание, но при одном условии - если вы итак хотите заснуть и вам просто нужен помощник для глубокого сна. С затяжной бессонницей, особенно из-за депрессии, он конечно не справиться. Но! если днем перенервничали, или спали слишком долго до полудня, или провели бессоную ночь - помогает однозначно. Принимал за 30 минут до засыпания, просыпался бодрым и отдохнувшим.
user avatar
3 месяца назад • А.т. • Куплен на Маркете
Достоинства: иногда помогает заснуть.
user avatar
Год назад • ShowWomens • Куплен на Маркете
Достоинства: сплю
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