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Описание

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Альфа Нормикс таб. п/о плен., 200 мг, 28 шт.

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5.0
(29)
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Дозировка: 200 мг

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Количество штук в упаковке, шт.: 28

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Коротко о товаре

Артикул Маркета
3123167595
Тип препарата
Назначение
Действующее вещество
Возраст
от 12 лет
Инструкция
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энцефалопатия","transition":{"type":"list","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["36476390:36618449,36618400,36618084"]}}},{"name":"действующее вещество","value":"Рифаксимин","transition":{"type":"list","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28709039"]}}},{"name":"возраст","value":"от 12 лет"},{"name":"форма выпуска","value":"таблетки"},{"name":"страна-производитель","value":"Италия"}]}},"compactSpecs":{"12916071118273146004":{"specItems":[{"name":"Артикул Маркета","value":"3123167595","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный 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препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27272850:1,0"]}}},{"name":"Назначение","value":"диарея, дивертикулез, печеночная энцефалопатия","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["36476390:36618449,36618400,36618084"]}}},{"name":"Органы и системы","value":"пищеварительная система"},{"name":"Показания к применению","value":"Лечение желудочно-кишечных инфекций, вызываемых бактериями, чувствительными к рифаксимину, например, при острых желудочно-кишечных инфекциях, диареи путешественников, синдроме избыточного роста микроорганизмов в кишечнике, печёночной энцефалопатии, симптоматическом неосложнённом дивертикулезном заболевании ободочной кишки и хроническом воспалении кишечника.\u003Cbr\u003EПрофилактика инфекционных осложнений при колоректальных хирургических вмешательствах."},{"name":"Противопоказания","value":"- повышенная чувствительность к рифаксимину или другим из компонентов, входящих в состав препарата.\u003Cbr\u003E- диарея, сопровождающаяся лихорадкой и жидким стулом кровью.\u003Cbr\u003E- кишечная непроходимость (в том числе частичная).\u003Cbr\u003E- тяжелое язвенное поражение кишечника.\u003Cbr\u003E- детский возраст до 12 лет (эффективность и безопасность не установлены).\u003Cbr\u003E- наследственная непереносимость фруктозы, нарушение всасывания глюкозы-галактозы, недостаточность сахаразы-изомальтазы (для лекарственной формы гранулы для приготовления суспензии для приема внутрь)."},{"name":"Состав","value":"Для дозировки 200 мг: каждая таблетка, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EАктивное вещество: рифаксимин с полиморфной структурой альфа -200 мг.\u003Cbr\u003EВспомогательные вещества: карбоксиметилкрахмал натрия 15 мг, глицерил пальмитостеарат 18 мг, кремния диоксид коллоидный 1 мг, тальк 1 мг, целлюлоза микрокристаллическая 115 мг.\u003Cbr\u003EПленочная оболочка: гипромеллоза 5.15 мг, титана диоксид (Е171) 1,5 мг, динатрия эдетат 0,02 мг, пропиленгликоль 0,5 мг, оксид железа красный (Е 172) 0,15 мг.\u003Cbr\u003EДля дозировки 400 мг: каждая таблетка содержит:\u003Cbr\u003EДействующее вещество: рифаксимин 400 мг.\u003Cbr\u003EВспомогательные вещества: целлюлоза микрокристаллическая, тип 102, глицерид дистеарат, карбоксиметилкрахмал натрия, тип А, кремния диоксид коллоидный, тальк;\u003Cbr\u003E\nпленочная оболочка: гипромеллоза, титана диоксид (Е171), пропиленгликоль, динатрия эдетат, краситель железа оксид красный (Е172)."},{"name":"Действующее вещество","value":"Рифаксимин","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28709039"]}}},{"name":"Способ применения и дозы","value":"Дозировка 200 мг: \u003Cbr\u003E\nПринимать внутрь, запивая стаканом воды, независимо от приема пищи.\u003Cbr\u003EЛечение диареи: Взрослые и дети старше 12 лет: 1 таблетка по 200 мг (что эквивалентно 200 мг рифаксимина) каждые 6 часов. Лечение диареи путешественника не должно превышать 3 дней.\u003Cbr\u003EПеченочная энцефалопатия: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг (что эквивалентно 400 мг рифаксимина) каждые 8 часов.\u003Cbr\u003EПрофилактика постоперационных осложнений при колоректальных хирургических вмешательствах: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг (что эквивалентно 400 мг рифаксимина) каждые 12 часов. Профилактику проводят за 3 дня до операции.\u003Cbr\u003EСиндром избыточного бактериального роста: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг каждые 8-12 часов.\u003Cbr\u003EСимптоматический неосложненный дивертикулез: Взрослые и дети старше 12 лет: 1- 2 таблетки по 200 мг (что эквивалентно 200 - 400 мг рифаксимина) каждые 8-12 часов.\u003Cbr\u003EХронические воспалительные заболевания кишечника: Взрослые и дети старше 12 лет: 1-2 таблетки по 200 мг (что эквивалентно 200- 400 мг рифаксимина) каждые 8-12 часов.\u003Cbr\u003EПродолжительность лечения Альфа Нормиксом не должна превышать 7 дней. Повторный курс лечения следует проводить не ранее, чем через 20 - 40 дней. Общая продолжительность лечения определяется клиническим состоянием пациентов. По рекомендации врача могут быть изменены дозы и частота приёма.\u003Cbr\u003EКоррекция дозы у пациентов пожилого возраста и у пациентов с печеночной и почечной недостаточностью не требуется.\u003Cbr\u003E\nДозировка 400 мг:\u003Cbr\u003E\nПринимать внутрь, запивая стаканом воды, независимо от приёма пищи.\u003Cbr\u003E\nЛечение диареи:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов. Лечение диареи путешественника не должно превышать 3 дней.\u003Cbr\u003E\nПечёночная энцефалопатия:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8 часов.\u003Cbr\u003E\nПрофилактика постоперационных осложнений при колоректальных хирургических вмешательствах:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов. Профилактику проводят за 3 дня до операции.\u003Cbr\u003E\nСиндром избыточного бактериального роста:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8-12 часов.\u003Cbr\u003E\nСимптоматический неосложненный дивертикулёз:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов.\u003Cbr\u003E\nХронические воспалительные заболевания кишечника:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8-12 часов.\u003Cbr\u003E\nДля всех показаний продолжительность лечения не должна превышать 7 дней и зависит от состояния пациента. При необходимости повторный курс лечения следует проводить не ранее, чем через 20-40 дней. Общая продолжительность лечения определяется клиническим состоянием пациентов. По рекомендации врача могут быть изменены дозы и частота их приёма.\u003Cbr\u003E\nПациенты пожилого возраста:\u003Cbr\u003E\nФармакокинетика рифаксимина у пациентов пожилого возраста не изучалась, тем не менее коррекция дозы у данной группы пациентов не требуется.\u003Cbr\u003E\nПациенты с печёночной недостаточностью:\u003Cbr\u003E\nУ пациентов с печёночной недостаточностью коррекция дозы не требуется, пациентам с тяжёлой печёночной недостаточностью препарат следует применять с осторожностью\u003Cbr\u003E\nПациенты с почечной недостаточностью:\u003Cbr\u003E\nКоррекция дозы не требуется, у данной группы пациентов препарат следует применять с осторожностью"},{"name":"Побочные действия","value":"Побочные эффекты классифицированы по частоте встречаемости следующим образом: очень часто (≥ 1/10), часто (≥1/100 - \u003C1/10), нечасто (≥1/1000 - \u003C1/100), редко (≥1/10000 - \u003C1/1000), очень редко (\u003C1/10000), неизвестно (частота не может быть установлена на основании имеющихся данных).\u003Cbr\u003EСо стороны сердечно-сосудистой системы: Нечасто: ощущение сердцебиения, \"приливы\" крови к коже лица, повышение артериального давления.\u003Cbr\u003EСо стороны крови: Нечасто: лимфоцитоз, моноцитоз, нейтропения. Неизвестно: тромбоцитопения.\u003Cbr\u003E Со стороны иммунной системы: Неизвестно: анафилактические реакции, гиперчувствительность, анафилактический шок, отек гортани.\u003Cbr\u003E Метаболические нарушения: Нечасто: снижение аппетита, дегидратация.\u003Cbr\u003E Психические нарушения: Нечасто: патологические сновидения. депрессивное настроение, бессонница, нервозность.\u003Cbr\u003EСо стороны центральной нервной системы: Часто: головокружение, головная боль. Нечасто: гипестезия, мигрень. парестезия, сонливость, головная боль в области пазух носа. Неизвестно: предобморочное состояние, возбуждение.\u003Cbr\u003EСо стороны органа зрения: Нечасто: диплопия.\u003Cbr\u003E Со стороны внутреннего уха: Нечасто: боль в ухе, системное головокружение.\u003Cbr\u003E Со стороны органов дыхания: Нечасто: одышка, сухость в горле, заложенность носа, боль в ротоглотке, кашель, ринорея.\u003Cbr\u003E Со стороны желудочно-кишечного тракта и печени: Часто: вздутие живота, боль в животе, запор, диарея, метеоризм, тошнота, тенезмы, рвота, позывы на дефекацию. Нечасто: боль в верхней половине живота, асцит, диспепсия, нарушение моторики желудочно- кишечного тракта, выделение слизи и крови со стулом, сухость губ, \"твердый\" стул, повышение активности аспартатаминотрансферазы, агевзия.Неизвестно: нарушение печеночных функциональных тестов, изжога.\u003Cbr\u003E Со стороны мочевыделительной системы: Нечасто: глюкозурия, полиурия, поллакиурия, гематурия, протеинурия.\u003Cbr\u003E Со стороны кожи и подкожно-жировой клетчатки: Нечасто: сыпь, солнечный ожог.Неизвестно: ангионевротический отек, аллергический дерматит, эксфолиативный дерматит, экзема, эритема, зуд, пурпура, крапивница, эритематозная сыпь, эритема ладоней, зуд половых органов.\u003Cbr\u003E Со стороны опорно-двигательного аппарата: Нечасто: боль в спине, мышечный спазм, мышечная слабость, миалгия, боль в шее.\u003Cbr\u003E Инфекции: Нечасто: кандидоз, простой герпес, назофарингит, фарингит, инфекции верхних дыхательных путей.Неизвестно: клостридиальная инфекция.\u003Cbr\u003EСо стороны репродуктивной системы:Нечасто: полименорея.\u003Cbr\u003E Общие симптомы: Часто: лихорадка. Нечасто: астения, боль и неприятные ощущения неопределенной локализации, озноб, холодный пот, гриппоподобные симптомы, периферические отеки, гипергидроз, отек лица, усталость.\u003Cbr\u003E Лабораторные исследования: изменение международного нормализованного отношения."},{"name":"Фармакологическое действие","value":"Рифаксимин - антибиотик широкого спектра действия из группы рифамицина. Как и другие представители этой группы, необратимо связывает бета субъединицы фермента бактерий ДНК-зависимой РЕК полимеразы и, следовательно, ингибирует синтез РНК и белков бактерий.\u003Cbr\u003EВ результате необратимого связывания с ферментом, рифаксимин проявляет бактерицидные свойства в отношении чувствительных бактерий. Препарат обладает широким спектром противомикробной активности, включающим большинство грамотрицательных и грамположительных, аэробных и анаэробных бактерий.\u003Cbr\u003EШирокий антибактериальный спектр рифаксимина способствует снижению патогенной кишечной бактериальной нагрузки, которая обуславливает некоторые патологические состояния."},{"name":"Фармакологическая группа","value":"антибиотик-рифамицин"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 12 лет"},{"name":"Условия хранения","value":"При температуре не выше 30 °С. Хранить в местах, недоступных для детей."},{"name":"Передозировка","value":"По данным клинических исследований, у пациентов с диареей путешественника дозы рифаксимина до 1800 мг/день хорошо переносились. Даже у пациентов с нормальной бактериальной флорой кишечника рифаксимин в дозе до 2400 мг/день в течение 7 дней не вызывал неблагоприятных симптомов. При случайной передозировке показана симптоматическая и поддерживающая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Данные о применении Альфа Нормикса при беременности весьма ограничены. Исследования на животных показали преходящее влияние рифаксимина на оссификацию и строение скелета у плода. Клиническая значимость этих результатов неизвестна.\u003Cbr\u003EПрименение Альфа Нормикса при беременности не рекомендуется. Неизвестно, проникает ли рифаксимин в грудное молоко. Нельзя исключить риска для ребенка, находящегося на грудном вскармливании. Для решения вопроса о продолжении приема рифаксимина в период грудного вскармливания необходимо оценить соотношение риска для ребенка и пользы для матери."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Хотя головокружение и сонливость наблюдаются при применении препарата Альфа Нормикс, однако, он не оказывает существенного влияния на способность управлять автотранспортом и заниматься видами деятельности, требующими повышенного внимания и быстроты психомоторных реакций. В случае появления головокружения и сонливости при применении препарата, следует воздержаться от выполнения указанных видов деятельности."},{"name":"Особые указания","value":"Клинические данные свидетельствуют, что препарат Альфа Нормикс неэффективен при лечении кишечных инфекций, вызванных Campylobacter jejuni, Salmonella spp., Shigella spp, которые вызывают частую диарею, лихорадку, выделение крови со стулом. Препарат Альфа Нормикс не рекомендуется применять, если у пациентов наблюдаются лихорадка и жидкий стул с кровью. Препарат Альфа Нормикс следует отменить, если симптомы диареи усиливаются или сохраняются более 48 часов. Следует назначить другую антибактериальную терапию. Лечение диареи путешественника не должно превышать 3 дней.\u003Cbr\u003EИзвестно, что Clostridium difficile-ассоциированная диарея, может развиться при применении почти всех антибактериальных средств, включая препарат Альфа Нормикс. Потенциальную взаимосвязь препарата Альфа Нормикс с развитием Clostridium difficile-ассоциированной диареи и псевдомембранозного колита нельзя исключить. Опыт применения рифаксимина совместно с другими рифамицинами отсутствует. Пациентов необходимо предупредить, что, несмотря на незначительное всасывание рифаксимина (менее 1%), он может вызвать окрашивание мочи в красноватый цвет: это обусловлено активным веществом рифаксимином, который, как и большинство антибиотиков этого ряда (рифамицины), имеет красновато-оранжевую окраску. При развитии суперинфекции микроорганизмами, нечувствительными к рифаксимину, прием препарата Альфа Нормикс следует прекратить и назначить соответствующую терапию. Вследствие влияния препарата Альфа Нормикс на кишечную флору, эффективность пероральных контрацептивов, содержащих эстрогены, может снизиться после его приема. Рекомендуется применять дополнительные меры контрацепции при приеме препарата Альфа Нормикс, особенно, если содержание эстрогенов в пероральных контрацептивах менее 50 мкг. Прием препарата Альфа Нормикс возможен не ранее, чем через 2 часа после приема активированного угля. Гранулы для приготовления суспензии для приема внутрь содержат сахарозу, поэтому препарат Альфа Нормикс в данной лекарственной форме нельзя применять при наследственной непереносимости фруктозы, нарушении всасывания глюкозы- галактозы, недостаточности сахаразы-изомальтазы."},{"name":"Взаимодействие","value":"Исследования in vitro показывают, что рифаксимин не ингибирует изоферменты системы цитохрома Р-450 (CYP1A2, 2А6, 2В6, 2С8, 2С9, 2С19, 2D6,2Е1 и 3А4) и не индуцирует CYP 1А2 и CYP2B6, но является слабым индуктором CYP3A4. Клинические исследования лекарственного взаимодействия свидетельствуют, что у здоровых добровольцев рифаксимин не оказывает значительного влияния на фармакокинетику лекарственных средств, метаболизирующихся с участием CYP3A4. У пациентов с нарушением функции печени нельзя исключить, что рифаксимин может снизить экспозицию лекарственных средств субстратов CYP3A4 (например, варфарин, противоаритмические, противосудорожные и.т.д.) при одновременном применении с ними, так как при печеночной недостаточности имеет более высокую системную экспозицию по сравнению со здоровыми добровольцами. Исследования In vitro позволяют предполагать, что рифаксимин является умеренным субстратом Р- гликопротеина и метаболизируется с помощью изофермента CYP3 А4. Неизвестно, повышают ли системную экспозицию рифаксимина лекарственные средства, которые ингибируют Р-гликопротеин и/или CYP3A4 при одновременном применении с ним. Потенциальные взаимодействия рифаксимина с другими лекарственными средствами, которые подвергаются выведению из клетки с помощью Р-гликопротеина или других транспортных белков (MDRl, MRP2 MRP4, BCRP, BSEP), маловероятны."},{"name":"Регистрационный номер","value":"ЛС-001993; ЛП-008488"},{"name":"Дата государственной регистрации","value":"03.03.2021; 23.08.2022"},{"name":"Владелец регистрационного удостоверения","value":"Alfasigma S.p.A.","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["34324371:35649313","7893318:16628329"]}}},{"name":"Изготовитель","value":"Альфасигма"},{"name":"Фасовщик","value":"Альфасигма"},{"name":"Страна бренда","value":"Италия"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Альфа Нормикс","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["17796364:18014738"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"12916071118273146004":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Назначение","value":"диарея, дивертикулез, печеночная энцефалопатия"},{"name":"Органы и системы","value":"пищеварительная система"},{"name":"Показания к применению","value":"Лечение желудочно-кишечных инфекций, вызываемых бактериями, чувствительными к рифаксимину, например, при острых желудочно-кишечных инфекциях, диареи путешественников, синдроме избыточного роста микроорганизмов в кишечнике, печёночной энцефалопатии, симптоматическом неосложнённом дивертикулезном заболевании ободочной кишки и хроническом воспалении кишечника.\u003Cbr\u003EПрофилактика инфекционных осложнений при колоректальных хирургических вмешательствах."},{"name":"Противопоказания","value":"- повышенная чувствительность к рифаксимину или другим из компонентов, входящих в состав препарата.\u003Cbr\u003E- диарея, сопровождающаяся лихорадкой и жидким стулом кровью.\u003Cbr\u003E- кишечная непроходимость (в том числе частичная).\u003Cbr\u003E- тяжелое язвенное поражение кишечника.\u003Cbr\u003E- детский возраст до 12 лет (эффективность и безопасность не установлены).\u003Cbr\u003E- наследственная непереносимость фруктозы, нарушение всасывания глюкозы-галактозы, недостаточность сахаразы-изомальтазы (для лекарственной формы гранулы для приготовления суспензии для приема внутрь)."},{"name":"Состав","value":"Для дозировки 200 мг: каждая таблетка, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EАктивное вещество: рифаксимин с полиморфной структурой альфа -200 мг.\u003Cbr\u003EВспомогательные вещества: карбоксиметилкрахмал натрия 15 мг, глицерил пальмитостеарат 18 мг, кремния диоксид коллоидный 1 мг, тальк 1 мг, целлюлоза микрокристаллическая 115 мг.\u003Cbr\u003EПленочная оболочка: гипромеллоза 5.15 мг, титана диоксид (Е171) 1,5 мг, динатрия эдетат 0,02 мг, пропиленгликоль 0,5 мг, оксид железа красный (Е 172) 0,15 мг.\u003Cbr\u003EДля дозировки 400 мг: каждая таблетка содержит:\u003Cbr\u003EДействующее вещество: рифаксимин 400 мг.\u003Cbr\u003EВспомогательные вещества: целлюлоза микрокристаллическая, тип 102, глицерид дистеарат, карбоксиметилкрахмал натрия, тип А, кремния диоксид коллоидный, тальк;\u003Cbr\u003E\nпленочная оболочка: гипромеллоза, титана диоксид (Е171), пропиленгликоль, динатрия эдетат, краситель железа оксид красный (Е172)."},{"name":"Действующее вещество","value":"Рифаксимин"},{"name":"Способ применения и дозы","value":"Дозировка 200 мг: \u003Cbr\u003E\nПринимать внутрь, запивая стаканом воды, независимо от приема пищи.\u003Cbr\u003EЛечение диареи: Взрослые и дети старше 12 лет: 1 таблетка по 200 мг (что эквивалентно 200 мг рифаксимина) каждые 6 часов. Лечение диареи путешественника не должно превышать 3 дней.\u003Cbr\u003EПеченочная энцефалопатия: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг (что эквивалентно 400 мг рифаксимина) каждые 8 часов.\u003Cbr\u003EПрофилактика постоперационных осложнений при колоректальных хирургических вмешательствах: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг (что эквивалентно 400 мг рифаксимина) каждые 12 часов. Профилактику проводят за 3 дня до операции.\u003Cbr\u003EСиндром избыточного бактериального роста: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг каждые 8-12 часов.\u003Cbr\u003EСимптоматический неосложненный дивертикулез: Взрослые и дети старше 12 лет: 1- 2 таблетки по 200 мг (что эквивалентно 200 - 400 мг рифаксимина) каждые 8-12 часов.\u003Cbr\u003EХронические воспалительные заболевания кишечника: Взрослые и дети старше 12 лет: 1-2 таблетки по 200 мг (что эквивалентно 200- 400 мг рифаксимина) каждые 8-12 часов.\u003Cbr\u003EПродолжительность лечения Альфа Нормиксом не должна превышать 7 дней. Повторный курс лечения следует проводить не ранее, чем через 20 - 40 дней. Общая продолжительность лечения определяется клиническим состоянием пациентов. По рекомендации врача могут быть изменены дозы и частота приёма.\u003Cbr\u003EКоррекция дозы у пациентов пожилого возраста и у пациентов с печеночной и почечной недостаточностью не требуется.\u003Cbr\u003E\nДозировка 400 мг:\u003Cbr\u003E\nПринимать внутрь, запивая стаканом воды, независимо от приёма пищи.\u003Cbr\u003E\nЛечение диареи:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов. Лечение диареи путешественника не должно превышать 3 дней.\u003Cbr\u003E\nПечёночная энцефалопатия:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8 часов.\u003Cbr\u003E\nПрофилактика постоперационных осложнений при колоректальных хирургических вмешательствах:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов. Профилактику проводят за 3 дня до операции.\u003Cbr\u003E\nСиндром избыточного бактериального роста:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8-12 часов.\u003Cbr\u003E\nСимптоматический неосложненный дивертикулёз:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов.\u003Cbr\u003E\nХронические воспалительные заболевания кишечника:\u003Cbr\u003E\nВзрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8-12 часов.\u003Cbr\u003E\nДля всех показаний продолжительность лечения не должна превышать 7 дней и зависит от состояния пациента. При необходимости повторный курс лечения следует проводить не ранее, чем через 20-40 дней. Общая продолжительность лечения определяется клиническим состоянием пациентов. По рекомендации врача могут быть изменены дозы и частота их приёма.\u003Cbr\u003E\nПациенты пожилого возраста:\u003Cbr\u003E\nФармакокинетика рифаксимина у пациентов пожилого возраста не изучалась, тем не менее коррекция дозы у данной группы пациентов не требуется.\u003Cbr\u003E\nПациенты с печёночной недостаточностью:\u003Cbr\u003E\nУ пациентов с печёночной недостаточностью коррекция дозы не требуется, пациентам с тяжёлой печёночной недостаточностью препарат следует применять с осторожностью\u003Cbr\u003E\nПациенты с почечной недостаточностью:\u003Cbr\u003E\nКоррекция дозы не требуется, у данной группы пациентов препарат следует применять с осторожностью"},{"name":"Побочные действия","value":"Побочные эффекты классифицированы по частоте встречаемости следующим образом: очень часто (≥ 1/10), часто (≥1/100 - \u003C1/10), нечасто (≥1/1000 - \u003C1/100), редко (≥1/10000 - \u003C1/1000), очень редко (\u003C1/10000), неизвестно (частота не может быть установлена на основании имеющихся данных).\u003Cbr\u003EСо стороны сердечно-сосудистой системы: Нечасто: ощущение сердцебиения, \"приливы\" крови к коже лица, повышение артериального давления.\u003Cbr\u003EСо стороны крови: Нечасто: лимфоцитоз, моноцитоз, нейтропения. Неизвестно: тромбоцитопения.\u003Cbr\u003E Со стороны иммунной системы: Неизвестно: анафилактические реакции, гиперчувствительность, анафилактический шок, отек гортани.\u003Cbr\u003E Метаболические нарушения: Нечасто: снижение аппетита, дегидратация.\u003Cbr\u003E Психические нарушения: Нечасто: патологические сновидения. депрессивное настроение, бессонница, нервозность.\u003Cbr\u003EСо стороны центральной нервной системы: Часто: головокружение, головная боль. Нечасто: гипестезия, мигрень. парестезия, сонливость, головная боль в области пазух носа. Неизвестно: предобморочное состояние, возбуждение.\u003Cbr\u003EСо стороны органа зрения: Нечасто: диплопия.\u003Cbr\u003E Со стороны внутреннего уха: Нечасто: боль в ухе, системное головокружение.\u003Cbr\u003E Со стороны органов дыхания: Нечасто: одышка, сухость в горле, заложенность носа, боль в ротоглотке, кашель, ринорея.\u003Cbr\u003E Со стороны желудочно-кишечного тракта и печени: Часто: вздутие живота, боль в животе, запор, диарея, метеоризм, тошнота, тенезмы, рвота, позывы на дефекацию. Нечасто: боль в верхней половине живота, асцит, диспепсия, нарушение моторики желудочно- кишечного тракта, выделение слизи и крови со стулом, сухость губ, \"твердый\" стул, повышение активности аспартатаминотрансферазы, агевзия.Неизвестно: нарушение печеночных функциональных тестов, изжога.\u003Cbr\u003E Со стороны мочевыделительной системы: Нечасто: глюкозурия, полиурия, поллакиурия, гематурия, протеинурия.\u003Cbr\u003E Со стороны кожи и подкожно-жировой клетчатки: Нечасто: сыпь, солнечный ожог.Неизвестно: ангионевротический отек, аллергический дерматит, эксфолиативный дерматит, экзема, эритема, зуд, пурпура, крапивница, эритематозная сыпь, эритема ладоней, зуд половых органов.\u003Cbr\u003E Со стороны опорно-двигательного аппарата: Нечасто: боль в спине, мышечный спазм, мышечная слабость, миалгия, боль в шее.\u003Cbr\u003E Инфекции: Нечасто: кандидоз, простой герпес, назофарингит, фарингит, инфекции верхних дыхательных путей.Неизвестно: клостридиальная инфекция.\u003Cbr\u003EСо стороны репродуктивной системы:Нечасто: полименорея.\u003Cbr\u003E Общие симптомы: Часто: лихорадка. Нечасто: астения, боль и неприятные ощущения неопределенной локализации, озноб, холодный пот, гриппоподобные симптомы, периферические отеки, гипергидроз, отек лица, усталость.\u003Cbr\u003E Лабораторные исследования: изменение международного нормализованного отношения."},{"name":"Фармакологическое действие","value":"Рифаксимин - антибиотик широкого спектра действия из группы рифамицина. Как и другие представители этой группы, необратимо связывает бета субъединицы фермента бактерий ДНК-зависимой РЕК полимеразы и, следовательно, ингибирует синтез РНК и белков бактерий.\u003Cbr\u003EВ результате необратимого связывания с ферментом, рифаксимин проявляет бактерицидные свойства в отношении чувствительных бактерий. Препарат обладает широким спектром противомикробной активности, включающим большинство грамотрицательных и грамположительных, аэробных и анаэробных бактерий.\u003Cbr\u003EШирокий антибактериальный спектр рифаксимина способствует снижению патогенной кишечной бактериальной нагрузки, которая обуславливает некоторые патологические состояния."},{"name":"Фармакологическая группа","value":"антибиотик-рифамицин"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 12 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 30 °С. Хранить в местах, недоступных для детей."},{"name":"Передозировка","value":"По данным клинических исследований, у пациентов с диареей путешественника дозы рифаксимина до 1800 мг/день хорошо переносились. Даже у пациентов с нормальной бактериальной флорой кишечника рифаксимин в дозе до 2400 мг/день в течение 7 дней не вызывал неблагоприятных симптомов. При случайной передозировке показана симптоматическая и поддерживающая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Данные о применении Альфа Нормикса при беременности весьма ограничены. Исследования на животных показали преходящее влияние рифаксимина на оссификацию и строение скелета у плода. Клиническая значимость этих результатов неизвестна.\u003Cbr\u003EПрименение Альфа Нормикса при беременности не рекомендуется. Неизвестно, проникает ли рифаксимин в грудное молоко. Нельзя исключить риска для ребенка, находящегося на грудном вскармливании. Для решения вопроса о продолжении приема рифаксимина в период грудного вскармливания необходимо оценить соотношение риска для ребенка и пользы для матери."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Хотя головокружение и сонливость наблюдаются при применении препарата Альфа Нормикс, однако, он не оказывает существенного влияния на способность управлять автотранспортом и заниматься видами деятельности, требующими повышенного внимания и быстроты психомоторных реакций. В случае появления головокружения и сонливости при применении препарата, следует воздержаться от выполнения указанных видов деятельности."},{"name":"Особые указания","value":"Клинические данные свидетельствуют, что препарат Альфа Нормикс неэффективен при лечении кишечных инфекций, вызванных Campylobacter jejuni, Salmonella spp., Shigella spp, которые вызывают частую диарею, лихорадку, выделение крови со стулом. Препарат Альфа Нормикс не рекомендуется применять, если у пациентов наблюдаются лихорадка и жидкий стул с кровью. Препарат Альфа Нормикс следует отменить, если симптомы диареи усиливаются или сохраняются более 48 часов. Следует назначить другую антибактериальную терапию. Лечение диареи путешественника не должно превышать 3 дней.\u003Cbr\u003EИзвестно, что Clostridium difficile-ассоциированная диарея, может развиться при применении почти всех антибактериальных средств, включая препарат Альфа Нормикс. Потенциальную взаимосвязь препарата Альфа Нормикс с развитием Clostridium difficile-ассоциированной диареи и псевдомембранозного колита нельзя исключить. Опыт применения рифаксимина совместно с другими рифамицинами отсутствует. Пациентов необходимо предупредить, что, несмотря на незначительное всасывание рифаксимина (менее 1%), он может вызвать окрашивание мочи в красноватый цвет: это обусловлено активным веществом рифаксимином, который, как и большинство антибиотиков этого ряда (рифамицины), имеет красновато-оранжевую окраску. При развитии суперинфекции микроорганизмами, нечувствительными к рифаксимину, прием препарата Альфа Нормикс следует прекратить и назначить соответствующую терапию. Вследствие влияния препарата Альфа Нормикс на кишечную флору, эффективность пероральных контрацептивов, содержащих эстрогены, может снизиться после его приема. Рекомендуется применять дополнительные меры контрацепции при приеме препарата Альфа Нормикс, особенно, если содержание эстрогенов в пероральных контрацептивах менее 50 мкг. Прием препарата Альфа Нормикс возможен не ранее, чем через 2 часа после приема активированного угля. Гранулы для приготовления суспензии для приема внутрь содержат сахарозу, поэтому препарат Альфа Нормикс в данной лекарственной форме нельзя применять при наследственной непереносимости фруктозы, нарушении всасывания глюкозы- галактозы, недостаточности сахаразы-изомальтазы."},{"name":"Взаимодействие","value":"Исследования in vitro показывают, что рифаксимин не ингибирует изоферменты системы цитохрома Р-450 (CYP1A2, 2А6, 2В6, 2С8, 2С9, 2С19, 2D6,2Е1 и 3А4) и не индуцирует CYP 1А2 и CYP2B6, но является слабым индуктором CYP3A4. Клинические исследования лекарственного взаимодействия свидетельствуют, что у здоровых добровольцев рифаксимин не оказывает значительного влияния на фармакокинетику лекарственных средств, метаболизирующихся с участием CYP3A4. У пациентов с нарушением функции печени нельзя исключить, что рифаксимин может снизить экспозицию лекарственных средств субстратов CYP3A4 (например, варфарин, противоаритмические, противосудорожные и.т.д.) при одновременном применении с ними, так как при печеночной недостаточности имеет более высокую системную экспозицию по сравнению со здоровыми добровольцами. Исследования In vitro позволяют предполагать, что рифаксимин является умеренным субстратом Р- гликопротеина и метаболизируется с помощью изофермента CYP3 А4. Неизвестно, повышают ли системную экспозицию рифаксимина лекарственные средства, которые ингибируют Р-гликопротеин и/или CYP3A4 при одновременном применении с ним. Потенциальные взаимодействия рифаксимина с другими лекарственными средствами, которые подвергаются выведению из клетки с помощью Р-гликопротеина или других транспортных белков (MDRl, MRP2 MRP4, BCRP, BSEP), маловероятны."},{"name":"Регистрационный номер","value":"ЛС-001993; ЛП-008488"},{"name":"Дата государственной регистрации","value":"03.03.2021; 23.08.2022"},{"name":"Владелец регистрационного удостоверения","value":"Alfasigma S.p.A."},{"name":"Изготовитель","value":"Альфасигма"},{"name":"Фасовщик","value":"Альфасигма"},{"name":"Страна бренда","value":"Италия"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Альфа Нормикс"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_7804136379998055556"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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    Альфаксим таб. п/о плен., 200 мг, 20 шт.

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  • Альфаксим таб. п/о плен., 200 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o3p4uihn9n/toggleWishlist":{"skuId":"862217069","productId":1778177224,"offerId":"aD7paF3xnaIWGKzav8Yjtg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7viYpviQ4cdBEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIyKnzzwYQ7caRmwMY69zQByD33MEH","sign":"NmzXAhvtx+Im6/4afg8kCg+tObqI9TckGagQenlCcK0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o3p4uihn9n/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Альфаксим таб. п/о плен., 200 мг, 20 шт.

    Рейтинг товара: 4.5 из 5
    на основе 10 оценок
    Цена 872 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o3p4uihn9n/addToCartButton":{"offerId":"aD7paF3xnaIWGKzav8Yjtg","skuId":"862217069","pendingCartItem":{"productId":1778177224,"offerId":"aD7paF3xnaIWGKzav8Yjtg","showPlaceId":"OTNDnItfwRMjN9MRHuEMMlyiKxtmtKFLoHn9TLrVsqRPI8izUF_3UZn7-juZtVDehgF78ypq8GOngb0flHtPc2y5tEluTskgwPw6HAqsqhNB9MASyit6WY8gW6eRNMV-xjgvdQZRNhZf5Ffw6OoqW6__zT5nWNc7CkTu8VLFRN5WRmAIrc3H6D8za1AFqoupqtiB0QQz8xivGxmbXfHzlg,,","feeShow":"OTNDnItfwRMjN9MRHuEMMlyiKxtmtKFLoHn9TLrVsqRPI8izUF_3UZn7-juZtVDehgF78ypq8GOngb0flHtPc2y5tEluTskgwPw6HAqsqhNB9MASyit6WY8gW6eRNMV-xjgvdQZRNhZf5Ffw6OoqW6__zT5nWNc7CkTu8VLFRN5WRmAIrc3H6D8za1AFqoupqtiB0QQz8xivGxmbXfHzlg,,","skuId":"862217069","shopId":77075781,"price":{"applicablePriceDiscounts":[],"value":"872","currency":"RUR"},"hid":"15756919","name":"Альфаксим таб. п/о плен., 200 мг, 20 шт.","label":"tk29tclqyuj","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4721581,"key":"img_id2447380039117825298.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCkDTJdUMBhxLcrhkF1w97S0Dq4px-uGWx_On5fPKZgdLWQfj6AAujfSoKepGutILpZR6EyOzUKkQwi8rtD3XLy8Oq6YeFLLa4_NFdlCY-yoWbelTiht8mpp8_2E2yLA33BHe_jajKrfICpe4gXzE91Uv_Fk7WRKgojd2cMfnf6SxoTH2zUBnxcxNWwB6fu0EgntN0Q6Vy7NR2JMUNviOKy0bJy4ly_6pgJJuzkgqoumvh4Kbu6tvRfZfeu23fo6ytFdKIC5Z1csCd8cPW3skmL0GInIHAvT5Sx3PVCk0tTneQpDQYmMF1QNf2-p75EklJwrjY-p0TEUX9elkTAduhhdMohvipiJ0Y3af3WSPoS2mmPDcB7OOdlWlUwvep_M9rC-Mimn3OTDY3-SDoUHWydT3r1yTAMBz-7cMzfG1NTQfys87b2_ZL89_D-l6AbOa2unE4OSN40Nr9pg-CQzUQNkSwFPpvCtFIv0xvx9591EOVr6RknbKQe3b6r--LlgrThFZqgEQTN_LCcqUwfPwVtIc9QlzbP5HKHWBMLXzNwNogT4UTU1HIrESQBERNYekM6eJ3NYns5JH8mLaB1wqC943JGV0SQQ7cWcFJoZK2nPTgZzvOUHBusb7gwweIyaBhnfEYNFO3t7LokzcNyZzv_gFExuOF7pZdqu8SyhpUPxy6-JecZ-41z0NA9NHegbiaVCvyb-Eo3wonppmdMhhcKxwxLFjDIAiYMEMD_GBHQZF2P6UFcgDV40T_5hZB6n6ZZjRWfoabDgRZl6w1J2cbcV9LRsI0zP2qT6JqfpzIK3q-pLXUDiyJ5bpzgGaLWL3zxE4kMwa7mo0iBjWZVH8gl1fK15bqh5wA-tTNU4nKRvF7cDFK504AuQI8gxjKe5keW_H0d4NTUzJijs9COXrgR-j-PayDqeQuS3sMdnMlY9Y45tGwlYoqauaLmhMXTeqch6tPbO25DFqO5jA3-hEdlx90LS_jVfJ3wOu_kIYGkE5vMXCgd3-0uQLUamx5vLvaGEcJ210S23mftKkHmBsNLR5Z5kiZD7DM439n3MTArwX-H-OWzAegIWxHiUZ2ahPz7fjoaiGF1onY-Jcc_I6dbpf5s8iIbSBT3cvpJes8qceHPjuJM8sAyozK-WOrLY3lQeRgLcwjlSc0pTfOT2jK3lLajv-w0Foa1UvP5qODhYfFjXRleI3QevEoD3EHOcy6lUCqYVwuVoc4bPgAXB_4qJy72Lew2lLY9ZRcAFgLnMddi2RRo35rhyUGfNn_BwY_wnqz1T_nnNP7uxx3zdoJLZz5jp6V_drB9T31AWj8IR8X-Nr6UO_QywAUNSxr6gjSo89OCCXnk3592-sTc8YN1mnj1rlxybd0QSCOkUmDsILmEzfMMUw9WDTgu-E-mQfd-_lJSEHlxhu40_69y9zf3XKVDZIlsCNUINrmORwuS4cS_MXRyMVAbm2U_hmgpZFBMHcB2zyc124SJZIxqJr2t4s4q2YAdivbzbqgxu5TjGQQbZB0ZOpVZ7V1ido6Q7X2A5OkKrNytjMMlMW6fOBGVIZ8rLxdTQ4LLX7cUdyV3v2xCqFiwDliSl2TzSHEZqElBGE_pgnInPAM7SM29LGhSf2k9YmcnrwAc0AsR7IO9XkyBbmI9DRxFj15PiePeqtp8vOqGMcBJ7_iQd4-aUiVJQ3QiTZA40oZEbsfP6e_SmuN1RJdBM_x3ENAdx-ALAKdzsshawqVB3IuMkyXl5Kvg5luT2VxFbAl9HVNX1l_OE5JxjvWlvEh47u__LgbF8tuAUOjamXe2CS6StdhbWckJKowH_7TLfomYNvAAA61Q8upfAga2hNKtByTc12ltgeEFLBhI_1R6ge5lt0inOVWxZj6L26HDCczD6mJwHYZwvB2Vp4FOqKv701-DKKxwk8eSBZY00CYAqyrM1RkVzlfBm4LXERjqICC5r8vcy8U4Z7IhyjzBUE65NXmy-gjSXTMljVDrCqF9NWxdC2XzY53mcV7kKY5pUdPpsAPfJwRINyWnZ3veUUmFGvKS3A8unWJV3lPZVjQdyxJPOul6Sf1a1BnTMek7NuLUtalI8Bp1Yu2T6H0O7_dMUUSwcJe8OeWjq-kaGPmr3j5E8E2NCDA2FU79sZ9-ZEuzZWXtN18ksl_lYWNwmw7SIINcuIOx2QYAqxGDC6X_VjpeWjSNq9JcXafWHfz9fk_GG4yR-7Az8wfpxhsNwxH6c9lx26BrV7vVtg6HGUSf0EFLLodYqbjmCVrSJ17r91-b_wKODXonbQW7Hjj-5DtEM-1zX-R6l67AgBH5w0yQV3hMb03RyJWOAUHdSbf870-QJre339OXErGK9Wm16Do8yAMoVl9LDJxf1Kj3v5AxPnnW_gdKbn67uFZiJCpM_4e0wT1ltLXc3Agg1KeO63H1koaD0VZc-S2ZAQtHj6I4-83sgCyj1RqdVzb25FexmXdBJ-CfZKy8_Do4mzUoD0lwP5JetUZ_WDKlVVqpwJtE0Ngx6ou1NnGYKd4iJCojHEpT5qgUiZp5-LDyHErMVEXvKkWUeI218kEFVyPsGV0fwdrJg8PSRhwo_Cjfx7Cgua1fU-UtjpxX8YBuTxnAlk_XjcV55VD9Fow1GMghs_PXfQcE-7oGs4svNPLaY6gdcsyRPci7HQmdh8BIQEKPGiDu_PwI2t00zh0ED-ittBwULuVnk0Ij-00N6yFrOp4Rf9RG7W6NSHiiMWb65PPl5-Pgv6C0ps8rjudzZX6Vm670Jggf2Dj0PUicQnX1_9Q9dxPuioXpHzxSXMsl6Ytm1TCZG6AboyilhblFTuO2trq_TmY6ayjBQI2V0ucHX8QCbyx7JEiyQp0acMC007jN3pGf_Vb3BrL4-FAYQKqIcm-NX6yjg1jLpGwbTFZKfMLBGX1sskXyfittbI75JU5GaMR8ENI69sP5FVFWHmSYq3zYRZvZNJ7U8yOnzBAN8oB_6usL6-X7ETNpUtivtHAbICrDAipTinjixGf-vPcWqrc4fxL_bt2HkiJRD4EjEwJBHQaynbbFgrJOslXCnfE9IliVUtsQo9YXfFNt8sO5yaAgM3vKHIpxr7N4gE7TvkS3bzXJi6wFnMmwMMpbH1NIAASHz8PF0AtDn59drD1jf3mFDREYNL8qNK70dtODH61TNV7Qh7fWI8flatyVSXoscuURYZPurQUsK0S3lCX3aWzNzmEhjKDs6Khlo54xPp9oc0pFKlkTsh5EHRVVmi-vWG0vmsm4tqzGGcakKWakt2pryz6AZsNfrg74uBkFJfWALWD3YBU2QDGcAO5H5IYyVDcXBjY0CfYccYHsoud0nVFIQOTMf-VIr8lpA,/b64e=1/sign=9288ca84c9bd1c0b7931e0572301619f/keyno=MARKET_1/*","showUid":"17179752289331090235806002","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7viYpviQ4cdBEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIyKnzzwYQ7caRmwMY69zQByD33MEH","sign":"NmzXAhvtx+Im6/4afg8kCg+tObqI9TckGagQenlCcK0="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7viYpviQ4cdBEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIyKnzzwYQ7caRmwMY69zQByD33MEH","sign":"NmzXAhvtx+Im6/4afg8kCg+tObqI9TckGagQenlCcK0="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o3p4uihn9n/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Немозол таб. п/о плен., 400 мг, 1 шт.
    –17 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wpzne80co6/toggleWishlist":{"skuId":"227830327","productId":1434054472,"offerId":"lBKIhU7II1CDiD_NMnAjcg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7viYpviQ4cdBEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIyN7nqwUQt9TRbBiQ3tAHIPfcwQc=","sign":"4fASVQ8vbaNmD9Jz/S5X5CV7Xz5/vsWhTJMYupyFSx0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wpzne80co6/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Немозол таб. п/о плен., 400 мг, 1 шт.

    Рейтинг товара: 4.9 из 5
    на основе 43 оценки
    Цена 326 ₽ вместо 391
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  • Тройчатка Эвалар капс., 40 шт.
    –10 %
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    Тройчатка Эвалар капс., 40 шт.

    Рейтинг товара: 4.8 из 5
    на основе 266 оценок
    Цена 433 ₽ вместо 481
    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  • Плаквенил таб. п/о плен., 200 мг, 60 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-iivuxufeswj/toggleWishlist":{"skuId":"265313417","productId":1780859108,"offerId":"9vRmSPfX1TNwLzz48J9OZw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7viYpviQ4cdBEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI5IGX0QYQibnBfhi42KIFIPfcwQc=","sign":"9wI0U2FAm780HqF0AC2xScv2mxB45uhfyXWvzLKwG0Y="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-iivuxufeswj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Плаквенил таб. п/о плен., 200 мг, 60 шт.

    Рейтинг товара: 5 из 5
    на основе 8 оценок
    Цена 517 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-iivuxufeswj/addToCartButton":{"offerId":"9vRmSPfX1TNwLzz48J9OZw","skuId":"265313417","pendingCartItem":{"productId":1780859108,"offerId":"9vRmSPfX1TNwLzz48J9OZw","showPlaceId":"OTNDnItfwRMjN9MRHuEMMlyiKxtmtKFL2xaU34vEzL28yqkyQKG94B_2YEcDLAzEAbqYI6MTXqLQq1p0VgnCAwYJcYH7ZopJ93sgPqR-ZXs3-dPLja01AkzqmXj-_e3twJoge9jgyC0VK-SPgoKfRHH_Z79j35olJDgGtz37R4eLb-W4X8BcVK3pZe7VovASoT7SeoMo-6UbTkWk7NOl4g,,","feeShow":"OTNDnItfwRMjN9MRHuEMMlyiKxtmtKFL2xaU34vEzL28yqkyQKG94B_2YEcDLAzEAbqYI6MTXqLQq1p0VgnCAwYJcYH7ZopJ93sgPqR-ZXs3-dPLja01AkzqmXj-_e3twJoge9jgyC0VK-SPgoKfRHH_Z79j35olJDgGtz37R4eLb-W4X8BcVK3pZe7VovASoT7SeoMo-6UbTkWk7NOl4g,,","skuId":"265313417","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"517","currency":"RUR"},"hid":"15756919","name":"Плаквенил таб. п/о плен., 200 мг, 60 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  • Нормакс таб. п/о плен., 400 мг, 6 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cm2r5pn9um/toggleWishlist":{"skuId":"228063017","productId":1778176285,"offerId":"-wWg_kXABsQywz8slrhQnw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7viYpviQ4cdBEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUInaLzzwYQqe7fbBiQ3tAHIPfcwQc=","sign":"Vh3GeMEU6qchJYWRrDaRl/MOh1N7MXwu0KwI+o3vmbY="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cm2r5pn9um/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нормакс таб. п/о плен., 400 мг, 6 шт.

    Рейтинг товара: 4.3 из 5
    на основе 4 оценки
    Цена 273 ₽
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  • Рулид таб. п/о плен., 150 мг, 10 шт.
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    Рулид таб. п/о плен., 150 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 1 909 ₽
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  • Монурал гран. д/приг. р-ра д/вн. приема, 3 г, 3 г, 1 шт.
    –16 %
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    Монурал гран. д/приг. р-ра д/вн. приема, 3 г, 3 г, 1 шт.

    Рейтинг товара: 4.9 из 5
    на основе 40 оценок
    Цена 781 ₽ вместо 929
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  • Сумамед таб. п/о плен., 125 мг, 6 шт.
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    Сумамед таб. п/о плен., 125 мг, 6 шт.

    Рейтинг товара: 4.9 из 5
    на основе 33 оценки
    Цена 219 ₽
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  • Азитромицин капс., 500 мг, 3 шт.
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    Азитромицин капс., 500 мг, 3 шт.

    Рейтинг товара: 4.7 из 5
    на основе 156 оценок
    Цена 96 ₽
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  • Флуимуцил-антибиотик ИТ лиоф. д/приг. р-ра д/ин. и инг., 500 мг, 3 шт.
    –11 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mfs1mwi2cuc/toggleWishlist":{"skuId":"101286033775","productId":228092780,"offerId":"wc0UevR-Qvn14kS2_Iyk8A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7viYpviQ4cdBEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI7NbhbBDv8vio+QIY7t/QByD33MEH","sign":"4qUElgnlDUzTuy15JmcalOi5UqmXHtSYmGj5Ub5OHaE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mfs1mwi2cuc/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Флуимуцил-антибиотик ИТ лиоф. д/приг. р-ра д/ин. и инг., 500 мг, 3 шт.

    Рейтинг товара: 5 из 5
    на основе 46 оценок
    Цена 3 664 ₽ вместо 4 117
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Инструкция

Показания к применению

Лечение желудочно-кишечных инфекций, вызываемых бактериями, чувствительными к рифаксимину, например, при острых желудочно-кишечных инфекциях, диареи путешественников, синдроме избыточного роста микроорганизмов в кишечнике, печёночной энцефалопатии, симптоматическом неосложнённом дивертикулезном заболевании ободочной кишки и хроническом воспалении кишечника.
Профилактика инфекционных осложнений при колоректальных хирургических вмешательствах.

Противопоказания

- повышенная чувствительность к рифаксимину или другим из компонентов, входящих в состав препарата.
- диарея, сопровождающаяся лихорадкой и жидким стулом кровью.
- кишечная непроходимость (в том числе частичная).
- тяжелое язвенное поражение кишечника.
- детский возраст до 12 лет (эффективность и безопасность не установлены).
- наследственная непереносимость фруктозы, нарушение всасывания глюкозы-галактозы, недостаточность сахаразы-изомальтазы (для лекарственной формы гранулы для приготовления суспензии для приема внутрь).

Способ применения и дозы

Дозировка 200 мг:
Принимать внутрь, запивая стаканом воды, независимо от приема пищи.
Лечение диареи: Взрослые и дети старше 12 лет: 1 таблетка по 200 мг (что эквивалентно 200 мг рифаксимина) каждые 6 часов. Лечение диареи путешественника не должно превышать 3 дней.
Печеночная энцефалопатия: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг (что эквивалентно 400 мг рифаксимина) каждые 8 часов.
Профилактика постоперационных осложнений при колоректальных хирургических вмешательствах: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг (что эквивалентно 400 мг рифаксимина) каждые 12 часов. Профилактику проводят за 3 дня до операции.
Синдром избыточного бактериального роста: Взрослые и дети старше 12 лет: 2 таблетки по 200 мг каждые 8-12 часов.
Симптоматический неосложненный дивертикулез: Взрослые и дети старше 12 лет: 1- 2 таблетки по 200 мг (что эквивалентно 200 - 400 мг рифаксимина) каждые 8-12 часов.
Хронические воспалительные заболевания кишечника: Взрослые и дети старше 12 лет: 1-2 таблетки по 200 мг (что эквивалентно 200- 400 мг рифаксимина) каждые 8-12 часов.
Продолжительность лечения Альфа Нормиксом не должна превышать 7 дней. Повторный курс лечения следует проводить не ранее, чем через 20 - 40 дней. Общая продолжительность лечения определяется клиническим состоянием пациентов. По рекомендации врача могут быть изменены дозы и частота приёма.
Коррекция дозы у пациентов пожилого возраста и у пациентов с печеночной и почечной недостаточностью не требуется.
Дозировка 400 мг:
Принимать внутрь, запивая стаканом воды, независимо от приёма пищи.
Лечение диареи:
Взрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов. Лечение диареи путешественника не должно превышать 3 дней.
Печёночная энцефалопатия:
Взрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8 часов.
Профилактика постоперационных осложнений при колоректальных хирургических вмешательствах:
Взрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов. Профилактику проводят за 3 дня до операции.
Синдром избыточного бактериального роста:
Взрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8-12 часов.
Симптоматический неосложненный дивертикулёз:
Взрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 12 часов.
Хронические воспалительные заболевания кишечника:
Взрослые и дети старше 12 лет: 1 таблетка 400 мг каждые 8-12 часов.
Для всех показаний продолжительность лечения не должна превышать 7 дней и зависит от состояния пациента. При необходимости повторный курс лечения следует проводить не ранее, чем через 20-40 дней. Общая продолжительность лечения определяется клиническим состоянием пациентов. По рекомендации врача могут быть изменены дозы и частота их приёма.
Пациенты пожилого возраста:
Фармакокинетика рифаксимина у пациентов пожилого возраста не изучалась, тем не менее коррекция дозы у данной группы пациентов не требуется.
Пациенты с печёночной недостаточностью:
У пациентов с печёночной недостаточностью коррекция дозы не требуется, пациентам с тяжёлой печёночной недостаточностью препарат следует применять с осторожностью
Пациенты с почечной недостаточностью:
Коррекция дозы не требуется, у данной группы пациентов препарат следует применять с осторожностью
Полная инструкция
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Альфа Нормикс таб. п/о плен.
Альфа Нормикс таб. п/о плен., 200 мг, 28 шт.
5.0
(29)
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5 вопросов
Инструкция

1 892 ₽

Скидка: 17%
–17 %
Вместо:2 270 ₽
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5.0
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