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Описание

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Рениприл таб., 20 мг, 30 шт.

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5.0
(3)
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Дозировка: 20 мг

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Коротко о товаре

Артикул Маркета
3123173799
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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После приема начальной дозы больные должны находиться под медицинским наблюдением в течение 2 ч и дополнительно 1 ч, пока не стабилизируется АД. При необходимости и достаточно хорошей переносимости дозу можно увеличить до 40 мг/сут в 2 приема. Через 2-3 недели переходят на поддерживающую дозу - 10-40 мг/сут, разделенную на 1-2 приема. При умеренной артериальной гипертензии средняя суточная доза составляет около 10 мг.\u003Cbr\u003EМаксимальная суточная доза препарата составляет 40 мг/сут.\u003Cbr\u003EВ случае назначения пациентам, одновременно получающим диуретики, лечение диуретиком необходимо прекратить за 2-3 дня до назначения Рениприла. Если это невозможно, то начальная доза препарата должна составлять 2,5 мг/сут.\u003Cbr\u003EБольным с гипонатриемией (концентрация ионов натрия в сыворотке крови менее 130 ммоль/л) или концентрацией креатинина в сыворотке крови более 0,14 ммоль/л начальная доза - 2,5 мг 1 раз в сутки.\u003Cbr\u003EПри реноваскулярной гипертензии начальная доза - 2,5-5 мг/сутки. Максимальная суточная доза составляет 20 мг.\u003Cbr\u003EПри хронической сердечной недостаточности начальная доза составляет 2,5 мг однократно, затем дозу увеличивают на 2,5 - 5 мг через каждые 3-4 дня в соответствии с клинической реакцией до максимально переносимых доз в зависимости от величин АД, но не выше 40 мг/сут. однократно или в 2 приема. У больных с низким систолическим АД (менее 110 мм рт.ст.) терапию следует начинать с дозы 1,25 мг/сутки. Подбор дозы должен проводиться в течение 2-4 недель или в более короткие сроки. Средняя поддерживающая доза - 5-20 мг/сут. за 1-2 приема.\u003Cbr\u003EУ пожилых людей чаще наблюдается более выраженный гипотензивный эффект и удлинение времени действия препарата, что связано с уменьшением скорости выведения эналаприла, поэтому рекомендуемая начачьная доза пожилым - 1,25 мг.\u003Cbr\u003EПри хронической почечной недостаточности кумуляция наступает при снижении фильтрации менее 10 мл/мин. При клиренсе креатинина (КК) 80-30 мл/мин доза обычно составляет 5-10 мг/сут., при КК до 30-10 мл/мин - 2,5-5 мг/сут., при КК менее 10 мл/мин - 1,25-2,5 мг/сут. только в дни диализа.\u003Cbr\u003EДлительность лечения зависит от эффективности терапии. При слишком выраженном снижении АД дозу препарата постепенно уменьшают.\u003Cbr\u003EПрепарат применяют как в монотерапии, так и в сочетании с другими антигипертензивными средствами."},{"name":"Побочные действия","value":"Рениприл в целом хорошо переносится и в большинстве случаев не вызывает побочных действий, требующих отмены препарата.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: чрезмерное снижение АД, ортостатический коллапс, редко - загрудинная боль, стенокардия, инфаркт миокарда (обычно связаны с выраженным снижением АД), крайне редко - аритмии (предсердная бради- или тахикардия, мерцание предсердий), сердцебиение, тромбоэмболия ветвей легочной артерии.\u003Cbr\u003EСо стороны нервной системы: головокружение, головная боль, слабость, бессонница,тревога, спутанность сознания, повышенная утомляемость, сонливость (2-3%), очень редко при применении высоких доз - нервозность, депрессия, парестезии.\u003Cbr\u003EСо стороны органов чувств: нарушения вестибулярного аппарата, нарушения слуха и зрения, шум в ушах.\u003Cbr\u003EСо стороны пищеварительного тракта: сухость во рту, анорексия, диспепсические расстройства (тошнота, диарея или запор, рвота, боли в области живота), кишечная непроходимость, панкреатит, нарушение функции печени и желчевыделения, гепатит, желтуха.\u003Cbr\u003EСо стороны дыхательной системы: непродуктивный сухой кашель, интерстициальный пневмонит, бронхоспазм, одышка, ринорея, фарингит.\u003Cbr\u003EАллергические реакции: кожная сыпь, зуд, крапивница, ангионевротический отек, крайне редко - дисфония, полиморфная эритема, эксфолиативный дерматит, синдром Стивена- Джонсона, токсический эпидермальный некролиз, пемфигус, фотосенсибилизация, серозит, васкулит, миозит, артралгия, артрит, стоматит, глоссит.\u003Cbr\u003EСо стороны лабораторных показателей: гиперкреатининемия, повышение содержания мочевины, повышение активности \"печеночных\" ферментов, гипербилирубинемия, гиперкалиемия, гипонатриемия. Отмечаются в некоторых случаях снижение гематокрита, повышение СОЭ, тромбоцитопения, нейтропения, агранулоцитоз (у больных с аутоиммунными заболеваниями), эозинофилия.\u003Cbr\u003EСо стороны мочевыделительной системы: нарушение функции почек, протеинурия. Прочие: алопеция, снижение либидо, приливы."},{"name":"Фармакологическое действие","value":"Рениприл - антигипертензивный препарат из группы ингибиторов АПФ. Эналаприл является \"пролекарством\": в результате его гидролиза образуется эналаприлат, который и ингибирует АПФ. Механизм его действия связан с уменьшением образования из ангиотензина I ангиотензина II, снижение содержания которого ведет к прямому уменьшению выделения альдостерона. При этом понижается общее периферическое сосудистое сопротивление, систолическое и диастолическое артериальное давление (АД), пост- и преднагрузка на миокард.\u003Cbr\u003EРасширяет артерии в большей степени, чем вены, при этом рефлекторного повышения частоты сердечных сокращений не отмечается.\u003Cbr\u003EГипотензивный эффект более выражен при высоком уровне ренина плазмы, чем при нормальном или сниженном его уровне. Снижение АД в терапевтических пределах не оказывает влияния на мозговое кровообращение, кровоток в сосудах мозга поддерживается на достаточном уровне и на фоне сниженного артериального давления. Усиливает коронарный и почечный кровоток.\u003Cbr\u003EПри длительном применении уменьшается гипертрофия левого желудочка миокарда и миоцитов стенок артерий резистивного типа, предотвращает прогрессирование сердечной недостаточности и замедляет развитие дилатации левого желудочка. Улучшает кровоснабжение ишемизированного миокарда. Снижает агрегацию тромбоцитов.\u003Cbr\u003EОбладает некоторым диуретическим эффектом.\u003Cbr\u003EВремя наступления гипотензивного эффекта при приеме внутрь - 1 ч., достигает максимума через 4-6 ч. и сохраняется до 24 ч. У некоторых больных для достижения оптимального уровня артериального давления необходима терапия на протяжении нескольких недель. При сердечной недостаточности заметный клинический эффект наблюдается при длительном применении - 6 месяцев и более."},{"name":"Фармакологическая группа","value":"ингибиторы АПФ"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: выраженное снижение АД вплоть до развития коллапса, инфаркта миокарда, острого нарушения мозгового кровообращения или тромбоэмболических осложнений, судороги,ступор.\u003Cbr\u003EЛечение: больного переводят в горизонтальное положение с низким изголовьем. В легких случаях показаны промывание желудка и прием внутрь солевого раствора, в более тяжелых случаях - мероприятия, направленные на стабилизацию АД: внутривенное введение физиологического раствора, плазмозаменителей, при необходимости - введение ангиотензина II, гемодиализ (скорость выведения эналаприлата в среднем составляет 62 мл/мин)."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В начале лечения, до завершения периода подбора дозы, необходимо воздерживаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как возможно головокружение, особенно после начальной дозы ингибитора АПФ у больных, принимающих диуретические средства."},{"name":"Особые указания","value":"Необходимо соблюдать осторожность при назначении Рениприла пациентам со сниженным объемом циркулирующей крови (в результате терапии диуретиками, при ограничении потребления поваренной соли, проведении гемодиализа, диарее и рвоте) - повышен риск внезапного и выраженного снижения АД после применения даже начальной дозы ингибитора АПФ. Транзиторная артериальная гипотензия не является противопоказанием для продолжения лечения препаратом после стабилизации АД. В случае повторного выраженного снижения АД следует уменьшить дозу или отменить препарат.\u003Cbr\u003EПрименение высокопроницаемых диализных мембран повышает риск развития анафилактической реакции. Коррекция режима дозирования в дни, свободные от диализа, должна осуществляться в зависимости от уровня АД.\u003Cbr\u003EДо и во время лечения ингибиторами АПФ необходим периодический контроль АД, показателей крови (концентрации гемоглобина, калия, креатинина, мочевины, активности \"печеночных\" ферментов), белка в моче.\u003Cbr\u003EСледует тщательно наблюдать за больными с тяжелой сердечной недостаточностью, ишемической болезнью сердца и заболеваниями сосудов мозга, у которых резкое снижение АД может привести к инфаркту миокарда, инсульту или нарушению функции почек.\u003Cbr\u003EВнезапная отмена лечения не приводит к синдрому \"отмены\" (резкому подъему АД).\u003Cbr\u003EЗа новорожденными и грудными детьми, которые подвергались внутриутробному воздействию ингибиторов АПФ, рекомендуется вести тщательное наблюдение для своевременного выявления выраженного снижения АД, олигурии, гиперкалиемии и неврологических расстройств, возможных вследствие уменьшения почечного и мозгового кровотока при снижении АД, вызванного ингибиторами АПФ. При олигурии необходимо поддержание АД и почечной перфузии путем введения соответствующих жидкостей и сосудосуживающих средств.\u003Cbr\u003EПеред исследованием функций паращитовидных желез препарат следует отменить. Алкоголь усиливает гипотензивное действие препарата.\u003Cbr\u003EПеред хирургическим вмешательством (включая стоматологию) необходимо предупредить хирурга/анестезиолога о применении ингибиторов АПФ.\u003Cbr\u003EПри наличии почечной недостаточности возможно снижение выведения активного метаболита, приводящее к увеличению его концентрации в плазме крови. Таким пациентам может потребоваться назначение меньших доз препарата.\u003Cbr\u003EУ пациентов с артериальной гипертензией и односторонним или двусторонним стенозом почечных артерий возможно повышение содержания мочевины и креатинина в сыворотке крови.\u003Cbr\u003EУ таких пациентов необходимо контролировать функцию почек в течение первых нескольких недель терапии. Может потребоваться снижение дозировки препарата.\u003Cbr\u003EСледует учитывать соотношение риска и потенциальной пользы при назначении Рениприла пациентам с коронарной и цереброваскулярной недостаточностью в связи с опасностью усиления ишемии при чрезмерной артериальной гипотензии.\u003Cbr\u003EПрепарат следует назначать с осторожностью пациентам с сахарным диабетом из-за риска развития гиперкалиемии.\u003Cbr\u003EПациенты, имеющие в анамнезе указания на ангионевротический отек, могут иметь повышенный риск развития ангионевротического отека на фоне лечения Рениприлом.\u003Cbr\u003EУ пациентов с выраженными аутоимунными заболеваниями, например, системной красной волчанкой или склеродермией, повышен риск развития нейтропении или агранулоцитоза на фоне приема Рениприла.\u003Cbr\u003EРекомендуется соблюдать осторожность при назначении Рениприла для терапии хронической сердечной недостаточности у пациентов, получавших сердечные гликозиды и/или диуретики.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EС осторожностью применять при первичном гиперальдостеронизме, двустороннем стенозе почечных артерий, стенозе артерии единственной почки, гиперкалиемии, состоянии после трансплантации почки; аортальном стенозе, митральном стенозе (с нарушениями гемодинамики), идиопатическом гипертрофическом субаортальном стенозе, системных заболеваниях соединительной ткани, ишемической болезни сердца, угнетение костномозгового кроветворения, цереброваскулярных заболеваниях, сахарном диабете, почечной недостаточности (протеинурия - более 1 г/сутки), печеночной недостаточности, у пациентов, соблюдающих диету с ограничением соли или находящихся на гемодиализе, при одновременном приеме с иммунодепрессантами и салуретиками, у пожилых людей (старше 65 лет), состояниях, сопровождающихся снижением объема циркулирующей крови (в том числе диарея, рвота)."},{"name":"Взаимодействие","value":"При одновременном назначении Рениприла с нестероидными противовоспалительными препаратами (НПВП), эстрогенами возможно снижение гипотензивного эффекта; с калийсберегаюгцими диуретиками (спиронолактон, триамтерен, амилорид) может привести к гиперкалиемии; с солями лития - к замедлению выведения лития (показан контроль концентрации лития в плазме крови).\u003Cbr\u003EОдновременный прием с жаропонижающими и болеутоляющими средствами может уменьшить эффективность эналаприла.\u003Cbr\u003EЭналаприл ослабляет действие препаратов, содержащих теофиллин.\u003Cbr\u003EГипотензивное действие эналаприла усиливают диуретики, бета-адреноблокаторы, метилдопа, нитраты, блокаторы \"медленных\" кальциевых каналов, гидралазин, празозин, лекарственные средства для общей анестезии, этанол.\u003Cbr\u003EИммунодепрессанты, аллопуринол, цитостатики усиливают гематотоксичность. Препараты, вызывающие угнетение костного мозга, повышают риск развития нейтропении и/или агранулоцитоза."},{"name":"Регистрационный номер","value":"Р N000084/01"},{"name":"Дата государственной регистрации","value":"25.07.2018"},{"name":"Владелец регистрационного удостоверения","value":"Фармстандарт-Лексредства","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:16227855"]}}},{"name":"Изготовитель","value":"Фармстандарт-Лексредства"},{"name":"Фасовщик","value":"Фармстандарт-Лексредства"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Рениприл","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:18010899"]}}},{"name":"Срок годности","value":"49 мес."}]}},"fullSpecsGrouped":{"18416330812381248596":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия, хроническая сердечная недостаточность"},{"name":"Показания к применению","value":"Артериальная гипертензия, при хронической сердечной недостаточности (в составе комбинированной терапии)."},{"name":"Противопоказания","value":"Повышенная чувствительность к эналаприлу и другим ингибиторам АПФ, наследственный или идиопатический отек, наличие в анамнезе ангионевротического отека, связанного с лечением ингибиторами АПФ, порфирия, беременность, период лактации, возраст до 18 лет (эффективность и безопасность не установлены)."},{"name":"Состав","value":"1 таблетка содержит активного вещества эналаприла малеата - 10 или 20 мг, а также вспомогательные вещества: лактоза, крахмал картофельный, повидон низкомолекулярный, кальция стеарат."},{"name":"Действующее вещество","value":"Эналаприл"},{"name":"Способ применения и дозы","value":"Назначают внутрь независимо от времени приема пищи.\u003Cbr\u003EПри монотерапии артериальной гипертензии начальная доза - 5 мг один раз в сутки.\u003Cbr\u003EПри отсутствии клинического эффекта через 1-2 недели дозу повышают на 5 мг. После приема начальной дозы больные должны находиться под медицинским наблюдением в течение 2 ч и дополнительно 1 ч, пока не стабилизируется АД. При необходимости и достаточно хорошей переносимости дозу можно увеличить до 40 мг/сут в 2 приема. Через 2-3 недели переходят на поддерживающую дозу - 10-40 мг/сут, разделенную на 1-2 приема. При умеренной артериальной гипертензии средняя суточная доза составляет около 10 мг.\u003Cbr\u003EМаксимальная суточная доза препарата составляет 40 мг/сут.\u003Cbr\u003EВ случае назначения пациентам, одновременно получающим диуретики, лечение диуретиком необходимо прекратить за 2-3 дня до назначения Рениприла. Если это невозможно, то начальная доза препарата должна составлять 2,5 мг/сут.\u003Cbr\u003EБольным с гипонатриемией (концентрация ионов натрия в сыворотке крови менее 130 ммоль/л) или концентрацией креатинина в сыворотке крови более 0,14 ммоль/л начальная доза - 2,5 мг 1 раз в сутки.\u003Cbr\u003EПри реноваскулярной гипертензии начальная доза - 2,5-5 мг/сутки. Максимальная суточная доза составляет 20 мг.\u003Cbr\u003EПри хронической сердечной недостаточности начальная доза составляет 2,5 мг однократно, затем дозу увеличивают на 2,5 - 5 мг через каждые 3-4 дня в соответствии с клинической реакцией до максимально переносимых доз в зависимости от величин АД, но не выше 40 мг/сут. однократно или в 2 приема. У больных с низким систолическим АД (менее 110 мм рт.ст.) терапию следует начинать с дозы 1,25 мг/сутки. Подбор дозы должен проводиться в течение 2-4 недель или в более короткие сроки. Средняя поддерживающая доза - 5-20 мг/сут. за 1-2 приема.\u003Cbr\u003EУ пожилых людей чаще наблюдается более выраженный гипотензивный эффект и удлинение времени действия препарата, что связано с уменьшением скорости выведения эналаприла, поэтому рекомендуемая начачьная доза пожилым - 1,25 мг.\u003Cbr\u003EПри хронической почечной недостаточности кумуляция наступает при снижении фильтрации менее 10 мл/мин. При клиренсе креатинина (КК) 80-30 мл/мин доза обычно составляет 5-10 мг/сут., при КК до 30-10 мл/мин - 2,5-5 мг/сут., при КК менее 10 мл/мин - 1,25-2,5 мг/сут. только в дни диализа.\u003Cbr\u003EДлительность лечения зависит от эффективности терапии. При слишком выраженном снижении АД дозу препарата постепенно уменьшают.\u003Cbr\u003EПрепарат применяют как в монотерапии, так и в сочетании с другими антигипертензивными средствами."},{"name":"Побочные действия","value":"Рениприл в целом хорошо переносится и в большинстве случаев не вызывает побочных действий, требующих отмены препарата.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: чрезмерное снижение АД, ортостатический коллапс, редко - загрудинная боль, стенокардия, инфаркт миокарда (обычно связаны с выраженным снижением АД), крайне редко - аритмии (предсердная бради- или тахикардия, мерцание предсердий), сердцебиение, тромбоэмболия ветвей легочной артерии.\u003Cbr\u003EСо стороны нервной системы: головокружение, головная боль, слабость, бессонница,тревога, спутанность сознания, повышенная утомляемость, сонливость (2-3%), очень редко при применении высоких доз - нервозность, депрессия, парестезии.\u003Cbr\u003EСо стороны органов чувств: нарушения вестибулярного аппарата, нарушения слуха и зрения, шум в ушах.\u003Cbr\u003EСо стороны пищеварительного тракта: сухость во рту, анорексия, диспепсические расстройства (тошнота, диарея или запор, рвота, боли в области живота), кишечная непроходимость, панкреатит, нарушение функции печени и желчевыделения, гепатит, желтуха.\u003Cbr\u003EСо стороны дыхательной системы: непродуктивный сухой кашель, интерстициальный пневмонит, бронхоспазм, одышка, ринорея, фарингит.\u003Cbr\u003EАллергические реакции: кожная сыпь, зуд, крапивница, ангионевротический отек, крайне редко - дисфония, полиморфная эритема, эксфолиативный дерматит, синдром Стивена- Джонсона, токсический эпидермальный некролиз, пемфигус, фотосенсибилизация, серозит, васкулит, миозит, артралгия, артрит, стоматит, глоссит.\u003Cbr\u003EСо стороны лабораторных показателей: гиперкреатининемия, повышение содержания мочевины, повышение активности \"печеночных\" ферментов, гипербилирубинемия, гиперкалиемия, гипонатриемия. Отмечаются в некоторых случаях снижение гематокрита, повышение СОЭ, тромбоцитопения, нейтропения, агранулоцитоз (у больных с аутоиммунными заболеваниями), эозинофилия.\u003Cbr\u003EСо стороны мочевыделительной системы: нарушение функции почек, протеинурия. Прочие: алопеция, снижение либидо, приливы."},{"name":"Фармакологическое действие","value":"Рениприл - антигипертензивный препарат из группы ингибиторов АПФ. Эналаприл является \"пролекарством\": в результате его гидролиза образуется эналаприлат, который и ингибирует АПФ. Механизм его действия связан с уменьшением образования из ангиотензина I ангиотензина II, снижение содержания которого ведет к прямому уменьшению выделения альдостерона. При этом понижается общее периферическое сосудистое сопротивление, систолическое и диастолическое артериальное давление (АД), пост- и преднагрузка на миокард.\u003Cbr\u003EРасширяет артерии в большей степени, чем вены, при этом рефлекторного повышения частоты сердечных сокращений не отмечается.\u003Cbr\u003EГипотензивный эффект более выражен при высоком уровне ренина плазмы, чем при нормальном или сниженном его уровне. Снижение АД в терапевтических пределах не оказывает влияния на мозговое кровообращение, кровоток в сосудах мозга поддерживается на достаточном уровне и на фоне сниженного артериального давления. Усиливает коронарный и почечный кровоток.\u003Cbr\u003EПри длительном применении уменьшается гипертрофия левого желудочка миокарда и миоцитов стенок артерий резистивного типа, предотвращает прогрессирование сердечной недостаточности и замедляет развитие дилатации левого желудочка. Улучшает кровоснабжение ишемизированного миокарда. Снижает агрегацию тромбоцитов.\u003Cbr\u003EОбладает некоторым диуретическим эффектом.\u003Cbr\u003EВремя наступления гипотензивного эффекта при приеме внутрь - 1 ч., достигает максимума через 4-6 ч. и сохраняется до 24 ч. У некоторых больных для достижения оптимального уровня артериального давления необходима терапия на протяжении нескольких недель. При сердечной недостаточности заметный клинический эффект наблюдается при длительном применении - 6 месяцев и более."},{"name":"Фармакологическая группа","value":"ингибиторы АПФ"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: выраженное снижение АД вплоть до развития коллапса, инфаркта миокарда, острого нарушения мозгового кровообращения или тромбоэмболических осложнений, судороги,ступор.\u003Cbr\u003EЛечение: больного переводят в горизонтальное положение с низким изголовьем. В легких случаях показаны промывание желудка и прием внутрь солевого раствора, в более тяжелых случаях - мероприятия, направленные на стабилизацию АД: внутривенное введение физиологического раствора, плазмозаменителей, при необходимости - введение ангиотензина II, гемодиализ (скорость выведения эналаприлата в среднем составляет 62 мл/мин)."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В начале лечения, до завершения периода подбора дозы, необходимо воздерживаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как возможно головокружение, особенно после начальной дозы ингибитора АПФ у больных, принимающих диуретические средства."},{"name":"Особые указания","value":"Необходимо соблюдать осторожность при назначении Рениприла пациентам со сниженным объемом циркулирующей крови (в результате терапии диуретиками, при ограничении потребления поваренной соли, проведении гемодиализа, диарее и рвоте) - повышен риск внезапного и выраженного снижения АД после применения даже начальной дозы ингибитора АПФ. Транзиторная артериальная гипотензия не является противопоказанием для продолжения лечения препаратом после стабилизации АД. В случае повторного выраженного снижения АД следует уменьшить дозу или отменить препарат.\u003Cbr\u003EПрименение высокопроницаемых диализных мембран повышает риск развития анафилактической реакции. Коррекция режима дозирования в дни, свободные от диализа, должна осуществляться в зависимости от уровня АД.\u003Cbr\u003EДо и во время лечения ингибиторами АПФ необходим периодический контроль АД, показателей крови (концентрации гемоглобина, калия, креатинина, мочевины, активности \"печеночных\" ферментов), белка в моче.\u003Cbr\u003EСледует тщательно наблюдать за больными с тяжелой сердечной недостаточностью, ишемической болезнью сердца и заболеваниями сосудов мозга, у которых резкое снижение АД может привести к инфаркту миокарда, инсульту или нарушению функции почек.\u003Cbr\u003EВнезапная отмена лечения не приводит к синдрому \"отмены\" (резкому подъему АД).\u003Cbr\u003EЗа новорожденными и грудными детьми, которые подвергались внутриутробному воздействию ингибиторов АПФ, рекомендуется вести тщательное наблюдение для своевременного выявления выраженного снижения АД, олигурии, гиперкалиемии и неврологических расстройств, возможных вследствие уменьшения почечного и мозгового кровотока при снижении АД, вызванного ингибиторами АПФ. При олигурии необходимо поддержание АД и почечной перфузии путем введения соответствующих жидкостей и сосудосуживающих средств.\u003Cbr\u003EПеред исследованием функций паращитовидных желез препарат следует отменить. Алкоголь усиливает гипотензивное действие препарата.\u003Cbr\u003EПеред хирургическим вмешательством (включая стоматологию) необходимо предупредить хирурга/анестезиолога о применении ингибиторов АПФ.\u003Cbr\u003EПри наличии почечной недостаточности возможно снижение выведения активного метаболита, приводящее к увеличению его концентрации в плазме крови. Таким пациентам может потребоваться назначение меньших доз препарата.\u003Cbr\u003EУ пациентов с артериальной гипертензией и односторонним или двусторонним стенозом почечных артерий возможно повышение содержания мочевины и креатинина в сыворотке крови.\u003Cbr\u003EУ таких пациентов необходимо контролировать функцию почек в течение первых нескольких недель терапии. Может потребоваться снижение дозировки препарата.\u003Cbr\u003EСледует учитывать соотношение риска и потенциальной пользы при назначении Рениприла пациентам с коронарной и цереброваскулярной недостаточностью в связи с опасностью усиления ишемии при чрезмерной артериальной гипотензии.\u003Cbr\u003EПрепарат следует назначать с осторожностью пациентам с сахарным диабетом из-за риска развития гиперкалиемии.\u003Cbr\u003EПациенты, имеющие в анамнезе указания на ангионевротический отек, могут иметь повышенный риск развития ангионевротического отека на фоне лечения Рениприлом.\u003Cbr\u003EУ пациентов с выраженными аутоимунными заболеваниями, например, системной красной волчанкой или склеродермией, повышен риск развития нейтропении или агранулоцитоза на фоне приема Рениприла.\u003Cbr\u003EРекомендуется соблюдать осторожность при назначении Рениприла для терапии хронической сердечной недостаточности у пациентов, получавших сердечные гликозиды и/или диуретики.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EС осторожностью применять при первичном гиперальдостеронизме, двустороннем стенозе почечных артерий, стенозе артерии единственной почки, гиперкалиемии, состоянии после трансплантации почки; аортальном стенозе, митральном стенозе (с нарушениями гемодинамики), идиопатическом гипертрофическом субаортальном стенозе, системных заболеваниях соединительной ткани, ишемической болезни сердца, угнетение костномозгового кроветворения, цереброваскулярных заболеваниях, сахарном диабете, почечной недостаточности (протеинурия - более 1 г/сутки), печеночной недостаточности, у пациентов, соблюдающих диету с ограничением соли или находящихся на гемодиализе, при одновременном приеме с иммунодепрессантами и салуретиками, у пожилых людей (старше 65 лет), состояниях, сопровождающихся снижением объема циркулирующей крови (в том числе диарея, рвота)."},{"name":"Взаимодействие","value":"При одновременном назначении Рениприла с нестероидными противовоспалительными препаратами (НПВП), эстрогенами возможно снижение гипотензивного эффекта; с калийсберегаюгцими диуретиками (спиронолактон, триамтерен, амилорид) может привести к гиперкалиемии; с солями лития - к замедлению выведения лития (показан контроль концентрации лития в плазме крови).\u003Cbr\u003EОдновременный прием с жаропонижающими и болеутоляющими средствами может уменьшить эффективность эналаприла.\u003Cbr\u003EЭналаприл ослабляет действие препаратов, содержащих теофиллин.\u003Cbr\u003EГипотензивное действие эналаприла усиливают диуретики, бета-адреноблокаторы, метилдопа, нитраты, блокаторы \"медленных\" кальциевых каналов, гидралазин, празозин, лекарственные средства для общей анестезии, этанол.\u003Cbr\u003EИммунодепрессанты, аллопуринол, цитостатики усиливают гематотоксичность. Препараты, вызывающие угнетение костного мозга, повышают риск развития нейтропении и/или агранулоцитоза."},{"name":"Регистрационный номер","value":"Р N000084/01"},{"name":"Дата государственной регистрации","value":"25.07.2018"},{"name":"Владелец регистрационного удостоверения","value":"Фармстандарт-Лексредства"},{"name":"Изготовитель","value":"Фармстандарт-Лексредства"},{"name":"Фасовщик","value":"Фармстандарт-Лексредства"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Рениприл"},{"name":"Срок годности","value":"49 мес."}]}],"transitionId":"tr_213902094267774108"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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  • Рениприл гт таб., 12.5 мг+10 мг, 20 шт.
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    Рениприл гт таб., 12.5 мг+10 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 227 ₽
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  • Ко-ренитек таб., 12.5 мг+20 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gzj3eizfuz/toggleWishlist":{"skuId":"101370459729","productId":265150315,"offerId":"ffwDemLxdja6BiHzfqxoaA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI6763fhDR7JnR+QIYi9TQByDX3MEH","sign":"tG0n5JpJjogxRz1unLIaH00/gbhp+vkFTESt1vN1lfE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gzj3eizfuz/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ко-ренитек таб., 12.5 мг+20 мг, 28 шт.

    Рейтинг товара: 4.9 из 5
    на основе 51 оценка
    Цена 658 ₽
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  • Энам таб., 5 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-j8tpz5zymtj/toggleWishlist":{"skuId":"228091431","productId":1401075809,"offerId":"qX6R6v9dnhNdMKusZQsjgA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI4fCKnAUQp8zhbBjAotUHINfcwQc=","sign":"aSOH2zuJRSn8I3qvgjXs8L/puk+2UmHFD40sGtvdg+4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-j8tpz5zymtj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Энам таб., 5 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 9 оценок
    Цена 40 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-j8tpz5zymtj/addToCartButton":{"offerId":"qX6R6v9dnhNdMKusZQsjgA","skuId":"228091431","pendingCartItem":{"productId":1401075809,"offerId":"qX6R6v9dnhNdMKusZQsjgA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMn_OuaUEMGIqhMSvRb1Qf_BLpyrqsY2fcQBTCjKkrZwo48cGUsU5BSZhOnF9aKAFI7jfl9Wt0nQWioNf-zOymuM0nU5r2VvRQpi3QuV3Ss85TWzUNmX8rTeEE-7vGqHVSO_W95xAXSMA-JPdjGuPUmkxh3IYH7IAkTQrqqcdgvBQ-aV13__y9oySRSAqyg-eyA,,","feeShow":"OTNDnItfwRMjN9MRHuEMMn_OuaUEMGIqhMSvRb1Qf_BLpyrqsY2fcQBTCjKkrZwo48cGUsU5BSZhOnF9aKAFI7jfl9Wt0nQWioNf-zOymuM0nU5r2VvRQpi3QuV3Ss85TWzUNmX8rTeEE-7vGqHVSO_W95xAXSMA-JPdjGuPUmkxh3IYH7IAkTQrqqcdgvBQ-aV13__y9oySRSAqyg-eyA,,","skuId":"228091431","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"40","currency":"RUR"},"hid":"15756887","name":"Энам таб., 5 мг, 20 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  • Энап таб., 20 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rrn31n82l6q/toggleWishlist":{"skuId":"228137090","productId":1401075469,"offerId":"VPoD2Zhy-MLLJmro61xauw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIje6KnAUQgrHkbBi21YcEINfcwQc=","sign":"HSjZmfQHBak8r3BENkNAoD8x6CdPtt5OUfm/wWP8hMM="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rrn31n82l6q/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Энап таб., 20 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 10 оценок
    Цена 150 ₽
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  • Эналаприл таб., 20 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-j0d6wz8hvks/toggleWishlist":{"skuId":"228094437","productId":1401075668,"offerId":"jdbBXCpEy-oVVtMDeGbYtA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI1O+KnAUQ5ePhbBjZ8c8GINfcwQc=","sign":"+TbyCOO8WVO0tdutY+Xa+IFEbNx6X9T/VJeXAGLwOSc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-j0d6wz8hvks/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл таб., 20 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 4 оценки
    Цена 131 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-j0d6wz8hvks/addToCartButton":{"offerId":"jdbBXCpEy-oVVtMDeGbYtA","skuId":"228094437","pendingCartItem":{"productId":1401075668,"offerId":"jdbBXCpEy-oVVtMDeGbYtA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMn_OuaUEMGIqnoCnBgbbnHZEoyH_sW9cDxjYH8hCGRCaP0j0OAttOAU28mrVpBNNY8DDivIAoPCsQzC2Va1MTpbmUACY1NNTEwTE_VzoQmtMyPt2Ux7MJXbuaHtlGgvfnaHR2YZQaotHoGeMg-mzMDizRih8NuAiw6p5tkfXowqpuO0WNfyqZ5zxHKQBZtbjdQ,,","feeShow":"OTNDnItfwRMjN9MRHuEMMn_OuaUEMGIqnoCnBgbbnHZEoyH_sW9cDxjYH8hCGRCaP0j0OAttOAU28mrVpBNNY8DDivIAoPCsQzC2Va1MTpbmUACY1NNTEwTE_VzoQmtMyPt2Ux7MJXbuaHtlGgvfnaHR2YZQaotHoGeMg-mzMDizRih8NuAiw6p5tkfXowqpuO0WNfyqZ5zxHKQBZtbjdQ,,","skuId":"228094437","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"131","currency":"RUR"},"hid":"15756887","name":"Эналаприл таб., 20 мг, 20 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  • Эналаприл таб., 10 мг, 50 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xte0fjb3u2f/toggleWishlist":{"skuId":"101875277953","productId":1784969488,"offerId":"qHHfl_F3UwgFTqeDiyp_Aw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIkPKR0wYQgcH1wfsCGJe2+wUg19zBBw==","sign":"9MFxOYeRiwRjGgA0MDxlidG10HH5lTLgh0DfkzTngM0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xte0fjb3u2f/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл таб., 10 мг, 50 шт.

    Рейтинг товара: 4.8 из 5
    на основе 55 оценок
    Цена 150 ₽
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  • Эналаприл таб., 10 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-3opthclhmkt/toggleWishlist":{"skuId":"228128573","productId":1401075719,"offerId":"bmol8gGUCz_MTeVEUgdcJQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIh/CKnAUQve7jbBjyrIIIINfcwQc=","sign":"fYNLDNBhsn7qOj/aXuoBXpZlTLh9z+vKzNoN/qz2ueM="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-3opthclhmkt/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл таб., 10 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 5 оценок
    Цена 119 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-3opthclhmkt/addToCartButton":{"offerId":"bmol8gGUCz_MTeVEUgdcJQ","skuId":"228128573","pendingCartItem":{"productId":1401075719,"offerId":"bmol8gGUCz_MTeVEUgdcJQ","showPlaceId":"OTNDnItfwRMjN9MRHuEMMn_OuaUEMGIqQGBcxeM0bzbDno0j0i1pyeR3lQlLaFu5tpcAJpBZEh5eIEXekmlHxKayr3xcaqKa7EVyaJ4iDxSml9KV2lbYZTAJ17r5AFLk1KWMiYmljbEtvBfm1IZ1zDgu8BjM4rzNcDmnuFUPIQN1l9yUx9wt-cvQfFWbXiDiFxuNNsUVJdZ0CnEnLvBcDw,,","feeShow":"OTNDnItfwRMjN9MRHuEMMn_OuaUEMGIqQGBcxeM0bzbDno0j0i1pyeR3lQlLaFu5tpcAJpBZEh5eIEXekmlHxKayr3xcaqKa7EVyaJ4iDxSml9KV2lbYZTAJ17r5AFLk1KWMiYmljbEtvBfm1IZ1zDgu8BjM4rzNcDmnuFUPIQN1l9yUx9wt-cvQfFWbXiDiFxuNNsUVJdZ0CnEnLvBcDw,,","skuId":"228128573","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"119","currency":"RUR"},"hid":"15756887","name":"Эналаприл таб., 10 мг, 28 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  • Эналаприл таб., 10 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-w8p2mumvhzh/toggleWishlist":{"skuId":"228095669","productId":1778174097,"offerId":"OEgb_NuXoJBrpswUUUqvLA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIkZHzzwYQte3hbBiV3dAHINfcwQc=","sign":"PU3AF/6L9R5/Cix9d5pMke2smoqa2+ZjljgW7ZzPhVI="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-w8p2mumvhzh/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл таб., 10 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 68 оценок
    Цена 38 ₽
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  • Эналаприл гексал таб., 10 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ljmy91pafr/toggleWishlist":{"skuId":"228128571","productId":1401075667,"offerId":"KyPPW78WahYABokqtcbtkQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI0++KnAUQu+7jbBjEnNAHINfcwQc=","sign":"ySQXA/PX4uzbntdLUFsPDF9yfJ9ujlIep6wtHkLj0Po="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ljmy91pafr/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл гексал таб., 10 мг, 20 шт.

    Рейтинг товара: 4.6 из 5
    на основе 65 оценок
    Цена 79 ₽
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  • Каптоприл таб., 50 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xwaj1oi1t3/toggleWishlist":{"skuId":"101813091770","productId":1401075819,"offerId":"8zHdnwtEqpxoYY1wgm8KYw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI6/CKnAUQuvuhpPsCGNfxzwYg19zBBw==","sign":"wTB5s/DXQ/Lo5RjwtHFZbUZbRixeViKrPrFfa7VUnMs="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xwaj1oi1t3/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Каптоприл таб., 50 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 16 оценок
    Цена 65 ₽
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  • Берлиприл 10 таб., 10 мг, 30 шт.
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    Берлиприл 10 таб., 10 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 137 ₽
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  • Эналаприл Гексал таб., 20 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kqqczidybeb/toggleWishlist":{"skuId":"101922734880","productId":1811768949,"offerId":"L1f3_HTaFVpOmfS2d4dRYQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQjLqyuK6KmbgdEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI9cz13wYQoIbG2PsCGMSc0Acg19zBBw==","sign":"rfYJ6YEBft+V+6AqPLPp7aEyHFzPVLBr5DTAKkZ3Qm0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kqqczidybeb/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эналаприл Гексал таб., 20 мг, 20 шт.

    Рейтинг товара: 4.5 из 5
    на основе 19 оценок
    Цена 91 ₽
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Инструкция

Показания к применению

Артериальная гипертензия, при хронической сердечной недостаточности (в составе комбинированной терапии).

Противопоказания

Повышенная чувствительность к эналаприлу и другим ингибиторам АПФ, наследственный или идиопатический отек, наличие в анамнезе ангионевротического отека, связанного с лечением ингибиторами АПФ, порфирия, беременность, период лактации, возраст до 18 лет (эффективность и безопасность не установлены).

Способ применения и дозы

Назначают внутрь независимо от времени приема пищи.
При монотерапии артериальной гипертензии начальная доза - 5 мг один раз в сутки.
При отсутствии клинического эффекта через 1-2 недели дозу повышают на 5 мг. После приема начальной дозы больные должны находиться под медицинским наблюдением в течение 2 ч и дополнительно 1 ч, пока не стабилизируется АД. При необходимости и достаточно хорошей переносимости дозу можно увеличить до 40 мг/сут в 2 приема. Через 2-3 недели переходят на поддерживающую дозу - 10-40 мг/сут, разделенную на 1-2 приема. При умеренной артериальной гипертензии средняя суточная доза составляет около 10 мг.
Максимальная суточная доза препарата составляет 40 мг/сут.
В случае назначения пациентам, одновременно получающим диуретики, лечение диуретиком необходимо прекратить за 2-3 дня до назначения Рениприла. Если это невозможно, то начальная доза препарата должна составлять 2,5 мг/сут.
Больным с гипонатриемией (концентрация ионов натрия в сыворотке крови менее 130 ммоль/л) или концентрацией креатинина в сыворотке крови более 0,14 ммоль/л начальная доза - 2,5 мг 1 раз в сутки.
При реноваскулярной гипертензии начальная доза - 2,5-5 мг/сутки. Максимальная суточная доза составляет 20 мг.
При хронической сердечной недостаточности начальная доза составляет 2,5 мг однократно, затем дозу увеличивают на 2,5 - 5 мг через каждые 3-4 дня в соответствии с клинической реакцией до максимально переносимых доз в зависимости от величин АД, но не выше 40 мг/сут. однократно или в 2 приема. У больных с низким систолическим АД (менее 110 мм рт.ст.) терапию следует начинать с дозы 1,25 мг/сутки. Подбор дозы должен проводиться в течение 2-4 недель или в более короткие сроки. Средняя поддерживающая доза - 5-20 мг/сут. за 1-2 приема.
У пожилых людей чаще наблюдается более выраженный гипотензивный эффект и удлинение времени действия препарата, что связано с уменьшением скорости выведения эналаприла, поэтому рекомендуемая начачьная доза пожилым - 1,25 мг.
При хронической почечной недостаточности кумуляция наступает при снижении фильтрации менее 10 мл/мин. При клиренсе креатинина (КК) 80-30 мл/мин доза обычно составляет 5-10 мг/сут., при КК до 30-10 мл/мин - 2,5-5 мг/сут., при КК менее 10 мл/мин - 1,25-2,5 мг/сут. только в дни диализа.
Длительность лечения зависит от эффективности терапии. При слишком выраженном снижении АД дозу препарата постепенно уменьшают.
Препарат применяют как в монотерапии, так и в сочетании с другими антигипертензивными средствами.
Полная инструкция
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Рениприл таб.
Рениприл таб., 20 мг, 30 шт.
5.0
(3)
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Задать вопрос
Инструкция

73 ₽

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5.0
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У продавца:3 оценки·1 отзыв
У всех продавцов:16 оценок·5 отзывов
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7 месяцев назад • Татьяна К. • Куплен на Маркете
Достоинства: Принимать эти лекарства - необходимость, более ничего не скажешь
Посмотреть все отзывы на Маркете
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