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Описание

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Актрапид hm р-р д/ин., 100 МЕ/мл, 10 мл, 1 шт.

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5.0
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Коротко о товаре

Артикул Маркета
3297519778
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"550758787315191032":{"specItems":[{"name":"Артикул Маркета","value":"3297519778","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"диабетическая кома и прекома, кетоацидоз, сахарный диабет, сахарный диабет 1 типа, сахарный диабет 2 типа","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["36476390:36618661,36618199,36618138,36617639,36617476"]}}},{"name":"действующее вещество","value":"Инсулин растворимый (человеческий генно-инженерный)","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["27144131:36090294"]}}},{"name":"возраст","value":"от 6 лет"},{"name":"форма выпуска","value":"раствор для инъекций"},{"name":"страна-производитель","value":"Дания"}]}},"compactSpecs":{"550758787315191032":{"specItems":[{"name":"Артикул Маркета","value":"3297519778","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Возраст","value":"От 6 лет"},{"name":"Форма выпуска","value":"Раствор для инъекций"},{"name":"Страна-производитель","value":"Дания"}]}},"fullSpecs":{"550758787315191032":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"эндокринная система"},{"name":"Назначение","value":"диабетическая кома и прекома, кетоацидоз, сахарный диабет, сахарный диабет 1 типа, сахарный диабет 2 типа","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["36476390:36618661,36618199,36618138,36617639,36617476"]}}},{"name":"Показания к применению","value":"Сахарный диабет типа 1, сахарный диабет типа 2: стадия резистентности к пероральным гипогликемическим ЛС, частичная резистентность к пероральным гипогликемическим ЛС (комбинированная терапия); диабетический кетоацидоз, кетоацидотическая и гиперосмолярная кома; сахарный диабет, возникший во время беременности (при неэффективности диетотерапии); для интермиттирующего применения у больных сахарным диабетом на фоне инфекций, сопровождающихся высокой температурой; при предстоящих хирургических операциях, травмах, родах, при нарушениях обмена веществ, перед переходом на лечение пролонгированными препаратами инсулина."},{"name":"Противопоказания","value":"Гиперчувствительность, гипогликемия."},{"name":"Состав","value":"Действующее вещество: инсулин растворимый (человеческий генно-инженерный) – 100 МЕ*\u003Cbr\u003EВспомогательные вещества: цинка хлорид, глицерол, метакрезол, хлористоводородной кислоты и/или натрия гидроксида раствор (для поддержания уровня pH), вода д/и\u003Cbr/\u003E"},{"name":"Действующее вещество","value":"Инсулин растворимый (человеческий генно-инженерный)","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["27144131:36090294"]}}},{"name":"Способ применения и дозы","value":"Доза и путь введения препарата определяется индивидуально в каждом конкретном случае на основании содержания глюкозы в крови до еды и через 1–2 ч после еды, а также в зависимости от степени глюкозурии и особенностей течения заболевания.\u003Cbr\u003EПрепарат вводят п/к, в/м, в/в, за 15–30 мин до приема пищи. Наиболее частый способ введения — п/к. При диабетическом кетоацидозе, диабетической коме, в период хирургического вмешательства — в/в и в/м.\u003Cbr\u003EПри монотерапии кратность введения обычно составляет 3 раза в сутки (при необходимости — до 5–6 раз в сутки), место инъекций каждый раз меняют во избежание развития липодистрофии (атрофии или гипертрофии подкожно-жировой клетчатки).\u003Cbr\u003EСредняя суточная доза составляет 30–40 ЕД, у детей — 8 ЕД, затем в средней суточной дозе — 0,5–1 ЕД/кг или 30–40 ЕД 1–3 раза в сутки, при необходимости — 5–6 раз в сутки. При суточной дозе, превышающей 0,6 ЕД/кг, инсулин необходимо вводить в виде 2 и более инъекций в различные области тела. Возможно комбинировать с инсулинами длительного действия.\u003Cbr\u003EРаствор инсулина набирают из флакона, прокалывая стерильной иглой шприца резиновую пробку, протертую после снятия алюминиевого колпачка этанолом."},{"name":"Побочные действия","value":"Аллергические реакции (крапивница, ангионевротический отек — лихорадка, одышка, снижение АД);\u003Cbr\u003Eгипогликемия (бледность кожных покровов, усиление потоотделения, испарина, сердцебиение, тремор, чувство голода, возбуждение, тревожность, парестезии в области рта, головная боль, сонливость, бессонница, страх, депрессивное настроение, раздражительность, необычное поведение, неуверенность движений, нарушения речи и зрения), гипогликемическая кома;\u003Cbr\u003Eгипергликемия и диабетический ацидоз (при низких дозах, пропуске инъекции, несоблюдении диеты, на фоне лихорадки и инфекций): сонливость, жажда, снижение аппетита, гиперемия лица);\u003Cbr\u003Eнарушение сознания (вплоть до развития прекоматозного и коматозного состояния);\u003Cbr\u003Eпреходящие нарушения зрения (обычно в начале терапии);\u003Cbr\u003Eиммунологические перекрестные реакции с инсулином человека; повышение титра антиинсулиновых антител с последующим ростом гликемии;\u003Cbr\u003Eгиперемия, зуд и липодистрофия (атрофия или гипертрофия подкожной жировой клетчатки) в месте введения.\u003Cbr\u003EВ начале лечения — отеки и нарушение рефракции (носят временный характер и проходят при продолжении лечения)."},{"name":"Фармакологическое действие","value":"Препарат инсулина короткого действия. Взаимодействуя со специфическим рецептором внешней мембраны клеток, образует инсулинрецепторный комплекс. Повышая синтез цАМФ (в жировых клетках и клетках печени) или непосредственно проникая в клетку (мышцы), инсулинрецепторный комплекс стимулирует внутриклеточные процессы, в т.ч. синтез ряда ключевых ферментов (гексокиназа, пируваткиназа, гликогенсинтетаза и др.). Снижение концентрации глюкозы в крови обусловлено повышением ее внутриклеточного транспорта, усилением поглощения и усвоения тканями, стимуляцией липогенеза, гликогеногенеза, синтеза белка, снижением скорости продукции глюкозы печенью (снижение распада гликогена) и др. После п/к инъекции действие наступает в течение 20–30 мин, достигает максимума через 1–3 ч и продолжается, в зависимости от дозы, 5–8 ч. Длительность действия препарата зависит от дозы, способа, места введения и имеет значительные индивидуальные особенности."},{"name":"Фармакологическая группа","value":"гипогликемическое средство - инсулин короткого действия"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["35947170:36763748"]}}},{"name":"Минимальный возраст применения","value":"от 6 лет"},{"name":"Продолжительность действия","value":"5-8 часов"},{"name":"Условия хранения","value":"ранить в холодильнике при температуре от 2oC до 8oC (не слишком близко к морозильной камере) в картонной пачке. Не замораживать.\u003Cbr\u003EДля вскрытого флакона: хранить при температуре не выше 25oC в течение 6 недель. Не рекомендуется хранить в холодильнике. Хранить флакон в картонной пачке для защиты от света.\u003Cbr\u003EПрепарат следует защищать от воздействия тепла и солнечного света.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: гипогликемия (слабость, \"холодный\" пот, бледность кожных покровов, сердцебиение, дрожь, нервозность, чувство голода, парестезии в кистях рук, ногах, губах, языке, головная боль), гипогликемическая кома, судороги.\u003Cbr\u003EЛечение: легкую гипогликемию больной может устранить самостоятельно, приняв внутрь сахар или богатые легкоусвояемыми углеводами продукты питания.\u003Cbr\u003EП/к, в/м или в/в вводят глюкагон или в/в гипертонический раствор декстрозы. При развитии гипогликемической комы в/в струйно вводят 20–40 мл (до 100 мл) 40% раствора декстрозы до тех пор, пока больной не выйдет из коматозного состояния."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Способность пациентов к концентрации внимания и скорость реакции могут нарушаться во время гипогликемии, что может представлять опасность в тех ситуациях, когда эти способности особенно необходимы (например, при управлении транспортными средствами или работе с машинами и механизмами).\u003Cbr\u003EПациентам необходимо рекомендовать предпринимать меры для предупреждения развития гипогликемии при управлении транспортными средствами. Это особенно важно для пациентов с отсутствием или снижением выраженности симптомов-предвестников развивающейся гипогликемии или пациентов с частыми эпизодами гипогликемии. В этих случаях следует рассмотреть целесообразность управления транспортными средствами и выполнения подобных работ."},{"name":"Особые указания","value":"Перед взятием инсулина из флакона необходимо проверить прозрачность раствора. При появлении инородных тел, помутнении или выпадении в осадок субстанции на стекле флакона препарат использоваться не может.\u003Cbr\u003EТемпература вводимого инсулина должна соответствовать комнатной. Дозу инсулина необходимо корректировать в случаях инфекционных заболеваний, при нарушении функции щитовидной железы, болезни Аддисона, гипопитуитаризме, ХПН и сахарном диабете у лиц старше 65 лет.\u003Cbr\u003EПричинами гипогликемии могут быть: передозировка инсулина, замена препарата, пропуск приема пищи, рвота, диарея, физическое напряжение; заболевания, снижающие потребность в инсулине (далеко зашедшие заболевания почек и печени, а также гипофункция коры надпочечников, гипофиза или щитовидной железы), смена места инъекции (например кожа на животе, плечо, бедро), а также взаимодействие с др. ЛС. Возможно снижение концентрации глюкозы в крови при переводе больного с инсулина животных на инсулин человека.\u003Cbr\u003EПеревод больного на инсулин человека должен быть всегда медицински обоснован и проводиться только под контролем врача. Склонность к развитию гипогликемии может ухудшать способность больных к активному участию в дорожном движении, а также к обслуживанию машин и механизмов.\u003Cbr\u003EБольные сахарным диабетом могут купировать ощущаемую ими самими легкую гипогликемию с помощью приема сахара или пищи с высоким содержанием углеводов (рекомендуется всегда иметь с собой не менее 20 г сахара). О перенесенной гипогликемии необходимо информировать лечащего врача для решения вопроса о необходимости коррекции лечения.\u003Cbr\u003EПри лечении инсулином короткого действия в единичных случаях возможно уменьшение или увеличение объема жировой ткани (липодистрофия) в области инъекции. Этих явлений в значительной степени удается избежать путем постоянной смены места инъекции. В период беременности необходимо учитывать снижение (I триместр) или увеличение (II–III триместры) потребности в инсулине. Во время родов и непосредственно после них потребность в инсулине может резко снизиться. В период лактации необходимо ежедневное наблюдение в течение нескольких месяцев (до стабилизации потребности в инсулине).\u003Cbr\u003EБольные, получающие более 100 ЕД инсулина в сутки, при смене препарата требуют госпитализации."},{"name":"Взаимодействие","value":"Фармацевтически несовместим с растворами др. ЛС.\u003Cbr\u003EГипогликемическое действие усиливают сульфонамиды (в т.ч. пероральные гипогликемические ЛС, сульфаниламиды), ингибиторы МАО (в т.ч. фуразолидон, прокарбазин, селегилин), ингибиторы карбоангидразы, ингибиторы АПФ, НПВП (в т.ч. салицилаты), анаболические стероиды (в т.ч. станозолол, оксандролон, метандростенолон), андрогены, бромокриптин, тетрациклины, клофибрат, кетоконазол, мебендазол, теофиллин, циклофосфамид, фенфлурамин, препараты Li+, пиридоксин, хинидин, хинин, хлорохинин, этанол.\u003Cbr\u003EГипогликемическое действие ослабляют глюкагон, соматропин, ГКС, пероральные контрацептивы, эстрогены, тиазидные и петлевые диуретики, БМКК, тиреоидные гормоны, гепарин, сульфинпиразон, симпатомиметики, даназол, трициклические антидепрессанты, клонидин, антагонисты кальция, диазоксид, морфин, марихуана, никотин, фенитоин, эпинефрин, блокаторы H1-гистаминовых рецепторов.\u003Cbr\u003EБета-адреноблокаторы, резерпин, октреотид, пентамидин могут как усиливать, так и ослаблять гипогликемическое действие инсулина."},{"name":"Регистрационный номер","value":"П N014272/02"},{"name":"Дата государственной регистрации","value":"10.07.2019"},{"name":"Владелец регистрационного удостоверения","value":"Novo Nordisk","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["34324371:35649313","7893318:14908913"]}}},{"name":"Страна бренда","value":"Дания"},{"name":"Страна-производитель","value":"Дания"},{"name":"Название препарата","value":"Актрапид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["17796364:18050969"]}}},{"name":"Срок годности","value":"29 мес."}]}},"fullSpecsGrouped":{"550758787315191032":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"эндокринная система"},{"name":"Назначение","value":"диабетическая кома и прекома, кетоацидоз, сахарный диабет, сахарный диабет 1 типа, сахарный диабет 2 типа"},{"name":"Показания к применению","value":"Сахарный диабет типа 1, сахарный диабет типа 2: стадия резистентности к пероральным гипогликемическим ЛС, частичная резистентность к пероральным гипогликемическим ЛС (комбинированная терапия); диабетический кетоацидоз, кетоацидотическая и гиперосмолярная кома; сахарный диабет, возникший во время беременности (при неэффективности диетотерапии); для интермиттирующего применения у больных сахарным диабетом на фоне инфекций, сопровождающихся высокой температурой; при предстоящих хирургических операциях, травмах, родах, при нарушениях обмена веществ, перед переходом на лечение пролонгированными препаратами инсулина."},{"name":"Противопоказания","value":"Гиперчувствительность, гипогликемия."},{"name":"Состав","value":"Действующее вещество: инсулин растворимый (человеческий генно-инженерный) – 100 МЕ*\u003Cbr\u003EВспомогательные вещества: цинка хлорид, глицерол, метакрезол, хлористоводородной кислоты и/или натрия гидроксида раствор (для поддержания уровня pH), вода д/и\u003Cbr/\u003E"},{"name":"Действующее вещество","value":"Инсулин растворимый (человеческий генно-инженерный)"},{"name":"Способ применения и дозы","value":"Доза и путь введения препарата определяется индивидуально в каждом конкретном случае на основании содержания глюкозы в крови до еды и через 1–2 ч после еды, а также в зависимости от степени глюкозурии и особенностей течения заболевания.\u003Cbr\u003EПрепарат вводят п/к, в/м, в/в, за 15–30 мин до приема пищи. Наиболее частый способ введения — п/к. При диабетическом кетоацидозе, диабетической коме, в период хирургического вмешательства — в/в и в/м.\u003Cbr\u003EПри монотерапии кратность введения обычно составляет 3 раза в сутки (при необходимости — до 5–6 раз в сутки), место инъекций каждый раз меняют во избежание развития липодистрофии (атрофии или гипертрофии подкожно-жировой клетчатки).\u003Cbr\u003EСредняя суточная доза составляет 30–40 ЕД, у детей — 8 ЕД, затем в средней суточной дозе — 0,5–1 ЕД/кг или 30–40 ЕД 1–3 раза в сутки, при необходимости — 5–6 раз в сутки. При суточной дозе, превышающей 0,6 ЕД/кг, инсулин необходимо вводить в виде 2 и более инъекций в различные области тела. Возможно комбинировать с инсулинами длительного действия.\u003Cbr\u003EРаствор инсулина набирают из флакона, прокалывая стерильной иглой шприца резиновую пробку, протертую после снятия алюминиевого колпачка этанолом."},{"name":"Побочные действия","value":"Аллергические реакции (крапивница, ангионевротический отек — лихорадка, одышка, снижение АД);\u003Cbr\u003Eгипогликемия (бледность кожных покровов, усиление потоотделения, испарина, сердцебиение, тремор, чувство голода, возбуждение, тревожность, парестезии в области рта, головная боль, сонливость, бессонница, страх, депрессивное настроение, раздражительность, необычное поведение, неуверенность движений, нарушения речи и зрения), гипогликемическая кома;\u003Cbr\u003Eгипергликемия и диабетический ацидоз (при низких дозах, пропуске инъекции, несоблюдении диеты, на фоне лихорадки и инфекций): сонливость, жажда, снижение аппетита, гиперемия лица);\u003Cbr\u003Eнарушение сознания (вплоть до развития прекоматозного и коматозного состояния);\u003Cbr\u003Eпреходящие нарушения зрения (обычно в начале терапии);\u003Cbr\u003Eиммунологические перекрестные реакции с инсулином человека; повышение титра антиинсулиновых антител с последующим ростом гликемии;\u003Cbr\u003Eгиперемия, зуд и липодистрофия (атрофия или гипертрофия подкожной жировой клетчатки) в месте введения.\u003Cbr\u003EВ начале лечения — отеки и нарушение рефракции (носят временный характер и проходят при продолжении лечения)."},{"name":"Фармакологическое действие","value":"Препарат инсулина короткого действия. Взаимодействуя со специфическим рецептором внешней мембраны клеток, образует инсулинрецепторный комплекс. Повышая синтез цАМФ (в жировых клетках и клетках печени) или непосредственно проникая в клетку (мышцы), инсулинрецепторный комплекс стимулирует внутриклеточные процессы, в т.ч. синтез ряда ключевых ферментов (гексокиназа, пируваткиназа, гликогенсинтетаза и др.). Снижение концентрации глюкозы в крови обусловлено повышением ее внутриклеточного транспорта, усилением поглощения и усвоения тканями, стимуляцией липогенеза, гликогеногенеза, синтеза белка, снижением скорости продукции глюкозы печенью (снижение распада гликогена) и др. После п/к инъекции действие наступает в течение 20–30 мин, достигает максимума через 1–3 ч и продолжается, в зависимости от дозы, 5–8 ч. Длительность действия препарата зависит от дозы, способа, места введения и имеет значительные индивидуальные особенности."},{"name":"Фармакологическая группа","value":"гипогликемическое средство - инсулин короткого действия"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный"},{"name":"Минимальный возраст применения","value":"от 6 лет"},{"name":"Продолжительность действия","value":"5-8 часов"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"ранить в холодильнике при температуре от 2oC до 8oC (не слишком близко к морозильной камере) в картонной пачке. Не замораживать.\u003Cbr\u003EДля вскрытого флакона: хранить при температуре не выше 25oC в течение 6 недель. Не рекомендуется хранить в холодильнике. Хранить флакон в картонной пачке для защиты от света.\u003Cbr\u003EПрепарат следует защищать от воздействия тепла и солнечного света.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: гипогликемия (слабость, \"холодный\" пот, бледность кожных покровов, сердцебиение, дрожь, нервозность, чувство голода, парестезии в кистях рук, ногах, губах, языке, головная боль), гипогликемическая кома, судороги.\u003Cbr\u003EЛечение: легкую гипогликемию больной может устранить самостоятельно, приняв внутрь сахар или богатые легкоусвояемыми углеводами продукты питания.\u003Cbr\u003EП/к, в/м или в/в вводят глюкагон или в/в гипертонический раствор декстрозы. При развитии гипогликемической комы в/в струйно вводят 20–40 мл (до 100 мл) 40% раствора декстрозы до тех пор, пока больной не выйдет из коматозного состояния."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Способность пациентов к концентрации внимания и скорость реакции могут нарушаться во время гипогликемии, что может представлять опасность в тех ситуациях, когда эти способности особенно необходимы (например, при управлении транспортными средствами или работе с машинами и механизмами).\u003Cbr\u003EПациентам необходимо рекомендовать предпринимать меры для предупреждения развития гипогликемии при управлении транспортными средствами. Это особенно важно для пациентов с отсутствием или снижением выраженности симптомов-предвестников развивающейся гипогликемии или пациентов с частыми эпизодами гипогликемии. В этих случаях следует рассмотреть целесообразность управления транспортными средствами и выполнения подобных работ."},{"name":"Особые указания","value":"Перед взятием инсулина из флакона необходимо проверить прозрачность раствора. При появлении инородных тел, помутнении или выпадении в осадок субстанции на стекле флакона препарат использоваться не может.\u003Cbr\u003EТемпература вводимого инсулина должна соответствовать комнатной. Дозу инсулина необходимо корректировать в случаях инфекционных заболеваний, при нарушении функции щитовидной железы, болезни Аддисона, гипопитуитаризме, ХПН и сахарном диабете у лиц старше 65 лет.\u003Cbr\u003EПричинами гипогликемии могут быть: передозировка инсулина, замена препарата, пропуск приема пищи, рвота, диарея, физическое напряжение; заболевания, снижающие потребность в инсулине (далеко зашедшие заболевания почек и печени, а также гипофункция коры надпочечников, гипофиза или щитовидной железы), смена места инъекции (например кожа на животе, плечо, бедро), а также взаимодействие с др. ЛС. Возможно снижение концентрации глюкозы в крови при переводе больного с инсулина животных на инсулин человека.\u003Cbr\u003EПеревод больного на инсулин человека должен быть всегда медицински обоснован и проводиться только под контролем врача. Склонность к развитию гипогликемии может ухудшать способность больных к активному участию в дорожном движении, а также к обслуживанию машин и механизмов.\u003Cbr\u003EБольные сахарным диабетом могут купировать ощущаемую ими самими легкую гипогликемию с помощью приема сахара или пищи с высоким содержанием углеводов (рекомендуется всегда иметь с собой не менее 20 г сахара). О перенесенной гипогликемии необходимо информировать лечащего врача для решения вопроса о необходимости коррекции лечения.\u003Cbr\u003EПри лечении инсулином короткого действия в единичных случаях возможно уменьшение или увеличение объема жировой ткани (липодистрофия) в области инъекции. Этих явлений в значительной степени удается избежать путем постоянной смены места инъекции. В период беременности необходимо учитывать снижение (I триместр) или увеличение (II–III триместры) потребности в инсулине. Во время родов и непосредственно после них потребность в инсулине может резко снизиться. В период лактации необходимо ежедневное наблюдение в течение нескольких месяцев (до стабилизации потребности в инсулине).\u003Cbr\u003EБольные, получающие более 100 ЕД инсулина в сутки, при смене препарата требуют госпитализации."},{"name":"Взаимодействие","value":"Фармацевтически несовместим с растворами др. ЛС.\u003Cbr\u003EГипогликемическое действие усиливают сульфонамиды (в т.ч. пероральные гипогликемические ЛС, сульфаниламиды), ингибиторы МАО (в т.ч. фуразолидон, прокарбазин, селегилин), ингибиторы карбоангидразы, ингибиторы АПФ, НПВП (в т.ч. салицилаты), анаболические стероиды (в т.ч. станозолол, оксандролон, метандростенолон), андрогены, бромокриптин, тетрациклины, клофибрат, кетоконазол, мебендазол, теофиллин, циклофосфамид, фенфлурамин, препараты Li+, пиридоксин, хинидин, хинин, хлорохинин, этанол.\u003Cbr\u003EГипогликемическое действие ослабляют глюкагон, соматропин, ГКС, пероральные контрацептивы, эстрогены, тиазидные и петлевые диуретики, БМКК, тиреоидные гормоны, гепарин, сульфинпиразон, симпатомиметики, даназол, трициклические антидепрессанты, клонидин, антагонисты кальция, диазоксид, морфин, марихуана, никотин, фенитоин, эпинефрин, блокаторы H1-гистаминовых рецепторов.\u003Cbr\u003EБета-адреноблокаторы, резерпин, октреотид, пентамидин могут как усиливать, так и ослаблять гипогликемическое действие инсулина."},{"name":"Регистрационный номер","value":"П N014272/02"},{"name":"Дата государственной регистрации","value":"10.07.2019"},{"name":"Владелец регистрационного удостоверения","value":"Novo Nordisk"},{"name":"Страна бренда","value":"Дания"},{"name":"Страна-производитель","value":"Дания"},{"name":"Название препарата","value":"Актрапид"},{"name":"Срок годности","value":"29 мес."}]}],"transitionId":"tr_17864289596453826364"}}}}
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    Цена 488 ₽
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  • Актрапид НМ Пенфилл р-р д/ин., 100 МЕ/мл, 3 мл, 5 шт.
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    Актрапид НМ Пенфилл р-р д/ин., 100 МЕ/мл, 3 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 1 005 ₽
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  • Туджео СолоСтар р-р для в/м введ.ен., 300 ЕД/мл, 1.5 мл, 3 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-orqafowmlvk/toggleWishlist":{"skuId":"662108006","productId":998360080,"offerId":"Tx6rENMLsjWxezCgn2XApw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ4sHtod3bndByEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIkIiH3AMQ5u7buwIYhIiHCCDe2cEH","sign":"4xUNY1fP+8/40ebHOYRgX2RSOf3vw4OLeMW6vqUDMrs="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-orqafowmlvk/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Туджео СолоСтар р-р для в/м введ.ен., 300 ЕД/мл, 1.5 мл, 3 шт.

    Рейтинг товара: 5 из 5
    на основе 8 оценок
    Цена 3 096 ₽
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  • Новорапид Флекспен р-р для п/к и в/в введ., 100 ЕД/мл, 3 мл, 5 шт.
    –11 %
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    Новорапид Флекспен р-р для п/к и в/в введ., 100 ЕД/мл, 3 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 18 оценок
    Цена 2 169 ₽ вместо 2 437
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  • Левемир ФлексПен р-р для в/м введ. шприц-ручка, 100 ЕД/мл, 3 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-7acnwcre8c/toggleWishlist":{"skuId":"101966586853","productId":1823627489,"offerId":"R7w1yZf6kOA7BahObe8nrw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ4sHtod3bndByEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI4bHJ5QYQ5ce67fsCGPH7jQcg3tnBBw==","sign":"uljeTu0X/E1F6D1kISCbMZKzxNuiybi/xdtOj/cuu3k="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-7acnwcre8c/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Левемир ФлексПен р-р для в/м введ. шприц-ручка, 100 ЕД/мл, 3 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 9 оценок
    Цена 2 835 ₽
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  • Ринсулин НПХ сусп. для п/к введ. фл., 100 МЕ/мл, 10 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-n45e74jh8f/toggleWishlist":{"skuId":"101370581744","productId":998482000,"offerId":"88-0u9odIj6A709mFEDVfw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ4sHtod3bndByEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI0MCO3AMQ8KWh0fkCGMPe0Acg3tnBBw==","sign":"K9o6tnkA0qvMWnCD02Ff1XZd5jrej6Pn42TecP3isH0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-n45e74jh8f/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ринсулин НПХ сусп. для п/к введ. фл., 100 МЕ/мл, 10 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 503 ₽
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  • Биосулин Р р-р д/ин. фл., 100 МЕ/мл, 10 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dndnuth8kxs/toggleWishlist":{"skuId":"573232085","productId":998499010,"offerId":"4zVFYCUEVIy7Cv8CjYV_DQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ4sHtod3bndByEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIwsWP3AMQ1aerkQIYrsLZByDe2cEH","sign":"GAgygtSUr3pQ6+LtCJe1G+6Nvy7ZTl6Z8pB1IwpdEMA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dndnuth8kxs/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Биосулин Р р-р д/ин. фл., 100 МЕ/мл, 10 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 606 ₽
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  • Биосулин Н сусп. для п/к введ. фл., 100 МЕ/мл, 10 мл, 1 шт.
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    Биосулин Н сусп. для п/к введ. фл., 100 МЕ/мл, 10 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 681 ₽
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  • Тресиба ФлексПен р-р для п/к введ. шприц-ручки, 100 ЕД/мл, 3 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-st21xtjggtg/toggleWishlist":{"skuId":"101759014029","productId":1753645952,"offerId":"c_rHsWwID6FaBTU1_gzzpQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ4sHtod3bndByEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIgIeaxAYQjam9ivsCGPH7jQcg3tnBBw==","sign":"YcXNIW7okuww1KtBLjIdrwmkOoRY95ZzZtzJYyAHlXo="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-st21xtjggtg/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тресиба ФлексПен р-р для п/к введ. шприц-ручки, 100 ЕД/мл, 3 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 4 754 ₽
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  • Лантус Солостар р-р для п/к введ. шприц-ручка, 100 ЕД/мл, 3 мл, 5 шт.
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    Лантус Солостар р-р для п/к введ. шприц-ручка, 100 ЕД/мл, 3 мл, 5 шт.

    Рейтинг товара: 4.9 из 5
    на основе 7 оценок
    Цена 3 367 ₽
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  • Хумалог Микс 25 сусп. д/ин. шприц-ручка КвикПен, 3 мл, 5 шт.
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    Хумалог Микс 25 сусп. д/ин. шприц-ручка КвикПен, 3 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 1 799 ₽
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Инструкция

Показания к применению

Сахарный диабет типа 1, сахарный диабет типа 2: стадия резистентности к пероральным гипогликемическим ЛС, частичная резистентность к пероральным гипогликемическим ЛС (комбинированная терапия); диабетический кетоацидоз, кетоацидотическая и гиперосмолярная кома; сахарный диабет, возникший во время беременности (при неэффективности диетотерапии); для интермиттирующего применения у больных сахарным диабетом на фоне инфекций, сопровождающихся высокой температурой; при предстоящих хирургических операциях, травмах, родах, при нарушениях обмена веществ, перед переходом на лечение пролонгированными препаратами инсулина.

Противопоказания

Гиперчувствительность, гипогликемия.

Способ применения и дозы

Доза и путь введения препарата определяется индивидуально в каждом конкретном случае на основании содержания глюкозы в крови до еды и через 1–2 ч после еды, а также в зависимости от степени глюкозурии и особенностей течения заболевания.
Препарат вводят п/к, в/м, в/в, за 15–30 мин до приема пищи. Наиболее частый способ введения — п/к. При диабетическом кетоацидозе, диабетической коме, в период хирургического вмешательства — в/в и в/м.
При монотерапии кратность введения обычно составляет 3 раза в сутки (при необходимости — до 5–6 раз в сутки), место инъекций каждый раз меняют во избежание развития липодистрофии (атрофии или гипертрофии подкожно-жировой клетчатки).
Средняя суточная доза составляет 30–40 ЕД, у детей — 8 ЕД, затем в средней суточной дозе — 0,5–1 ЕД/кг или 30–40 ЕД 1–3 раза в сутки, при необходимости — 5–6 раз в сутки. При суточной дозе, превышающей 0,6 ЕД/кг, инсулин необходимо вводить в виде 2 и более инъекций в различные области тела. Возможно комбинировать с инсулинами длительного действия.
Раствор инсулина набирают из флакона, прокалывая стерильной иглой шприца резиновую пробку, протертую после снятия алюминиевого колпачка этанолом.
Полная инструкция
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Актрапид hm р-р д/ин.
Актрапид hm р-р д/ин., 100 МЕ/мл, 10 мл, 1 шт.
5.0
(2)
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3 вопроса
Инструкция

449 ₽

Скидка: 10%
–10 %
Вместо:499 ₽
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5.0
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У продавца:2 оценки·1 отзыв
У всех продавцов:56 оценок·9 отзывов
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user avatar
2 года назад • Наталья С. • Куплен на Маркете
Комментарий: Нужно было срочно получить лекарство, доставили оперативно, спасибо,все целое, качественно упаковано
Посмотреть все отзывы на Маркете
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