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Депренорм МВ таб. с пролонг. высвоб., п/о плен., 35 мг, 60 шт.

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Количество штук в упаковке, шт.: 60

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Коротко о товаре

Артикул Маркета
3310889654
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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гипромеллоза (гидроксипропилметилцеллюлоза) 69,4 мг; кальция гидрофосфат 29,2 мг; коповидон 4,2 мг; кремния диоксид коллоидный 6,4 мг; магния стеарат 0,8 мг; целлюлоза микрокристаллическая (тип 302) 64,4 мг;\u003Cbr\u003Eсостав оболочки: Селекоат AQ-01673 розовый 7,0 мг, в том числе: гипромеллоза (гидроксипропилметилцеллюлоза) 2,8 мг, макрогол-400 (полиэтиленгликоль-400) 0,7 мг, макрогол-6000 (полиэтиленгликоль-6000) 0,7 мг, титана диоксид 2,1 мг, краситель пунцовый [Понсо 4 R] 0,7 мг.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Триметазидин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28708333"]}}},{"name":"Способ применения и дозы","value":"Таблетки Депренорм МВ следует принимать целиком, не разжевывая, запивая водой.\u003Cbr\u003EВнутрь, по 1 таблетке 2 раза в сутки, утром и вечером, во время еды.\u003Cbr\u003EОценка пользы от лечения должна быть проведена после трех месяцев приема препарата. Прием триметазидина следует прекратить, если за это время улучшение не наступило.\u003Cbr\u003EПродолжительность лечения определяется лечащим врачом.\u003Cbr\u003EОсобые группы\u003Cbr\u003EПациенты с нарушением функции почек\u003Cbr\u003EУ пациентов с умеренным нарушением функции почек (КК 30-60 мл/мин) суточная доза составляет 35 мг (1 таблетка), утром во время завтрака.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EУ пациентов пожилого возраста может наблюдаться повышенная экспозиция триметазидина из-за возрастного снижения функции почек (см. раздел \"Фармакологические свойства\"). 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Нарушения сна (бессонница, сонливость).\nСо стороны сердечно-сосудистой системы\nРедко: ортостатическая гипотензия, «приливы» крови к коже лица, ощущение сердцебиения, экстрасистолия, тахикардия, выраженное снижение АД.\nСо стороны кровеносной и лимфатической системы\nНеуточненной частоты: агранулоцитоз, тромбоцитопения, тромбоцитопеническая пурпура.\nСо стороны пищеварительной системы\nЧасто: боль в животе, диарея, диспепсия, тошнота, рвота.\nНеуточненной частоты: запор.\nСо стороны печени и желчевыводящих путей\nНеуточненной частоты: гепатит.\nСо стороны кожных покровов\nЧасто: кожная сыпь, зуд, крапивница.\nНеуточненной частоты: острый генерализованный экзантематозныи пустулез, отек Квинке.\nОбщие нарушения\nЧасто: астения.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Триметазидин предотвращает снижение внутриклеточной концентрации аденозинтрифосфата (АТФ) путем сохранения энергетического метаболизма клеток в состоянии гипоксии. Таким образом, препарат обеспечивает нормальное функционирование мембранных ионных каналов, трансмембранный перенос ионов калия и натрия и сохранение клеточного гомеостаза.\u003Cbr\u003EТриметазидин ингибирует окисление жирных кислот за счет селективного ингибирования фермента З-кетоацил-КоА-тиолазы (З-КАТ) митохондриальной длинноцепочечной изоформы жирных кислот, что приводит к усилению окисления глюкозы и ускорению гликолиза с окислением глюкозы, что и обусловливает защиту миокарда от ишемии. Переключение энергетического метаболизма с окисления жирных кислот на окисление глюкозы лежит в основе фармакологических свойств триметазидина.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"антиангинальное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °С, во вторичной упаковке (пачке картонной). Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Имеется лишь очень ограниченная информация о передозировке триметазидина. В случае передозировки следует проводить симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EДанные о применении триметазидина у беременных отсутствуют. Исследования на животных не выявили наличие прямого или непрямого негативного влияния в отношении репродуктивной функции.\u003Cbr\u003EПрименение препарата Депренорм MB во время беременности противопоказано.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EДанные о выделении или его метаболитов в грудное молоко отсутствуют. Риск для новорожденного/ребенка не может быть исключен. При необходимости применения лекарственного препарата Депренорм МВ в период лактации грудное вскармливание необходимо прекратить.\u003Cbr\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В ходе клинических исследований не было выявлено влияния триметазидина на показатели гемодинамики, однако в период пострегистрационного применения наблюдались случаи головокружения и сонливости (см. раздел «Побочное действие»), что может повлиять на способность к управлению автотранспортом и выполнение работ, требующих повышенной скорости физической и психической реакций."},{"name":"Особые указания","value":"С осторожностью:\nПациенты с умеренным нарушением функции почек (клиренс креатинина 30-60 мл/мин).\n\nПациенты старше 75 лет (см. разделы \"Способ применения и дозы\" и \"Особые указания\").\u003Cbr\u003EОсобые указания:\u003Cbr\u003EЛекарственный препарат Депренорм МВ не предназначен для купирования приступов стенокардии и не показан для начального курса терапии нестабильной стенокардии или инфаркта миокарда на догоспитальном этапе или в первые дни госпитализации.\u003Cbr\u003EВ случае развития приступа стенокардии следует вновь оценить степень поражения коронарных артерий и, при необходимости, адаптировать лечение (лекарственную терапию или возможное проведение процедуры реваскуляризации).\u003Cbr\u003EТриметазидин может вызывать или ухудшать симптомы паркинсонизма (тремор, акинезию, повышение тонуса), поэтому следует проводить регулярное наблюдение пациентов, особенно пожилого возраста. В сомнительных случаях пациенты должны быть направлены к неврологу для соответствующего обследования.\u003Cbr\u003EПри появлении двигательных нарушений, таких как симптомы паркинсонизма, синдром «беспокойных ног», тремор, неустойчивость походки, триметазидин следует окончательно отменить.\u003Cbr\u003EТакие случаи редки и симптомы обычно проходят после прекращения терапии: у большинства пациентов в течение 4 месяцев после отмены триметазидина. Если симптомы паркинсонизма сохраняются более 4 месяцев после отмены препарата, следует проконсультироваться у невролога.\u003Cbr\u003EМогут отмечаться случаи падения, связанные с неустойчивостью походки или артериальной гипотензией особенно у пациентов, принимающих гипотензивные препараты (см. раздел «Побочное действие»).\u003Cbr\u003EСледует с осторожностью назначать триметазидин пациентам, у которых возможно повышение его экспозиции:\u003Cbr\u003E- При нарушении функции почек умеренной степени тяжести (см. разделы «Фармакологические свойства» и «Способ применения и дозы»).\u003Cbr\u003E- У пожилых пациентов старше 75 лет (см. раздел «Способ применения и дозы»).\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Не было выявлено взаимодействий с другими лекарственными средствами."},{"name":"Регистрационный номер","value":"ЛС-001706"},{"name":"Дата государственной регистрации","value":"04.02.2021"},{"name":"Владелец регистрационного удостоверения","value":"Канонфарма продакшн","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:16146766"]}}},{"name":"Изготовитель","value":"Канонфарма продакшн"},{"name":"Фасовщик","value":"Канонфарма продакшн"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Депренорм","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:18017668"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"6494312213952954682":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносная система, сердце"},{"name":"Назначение","value":"ишемическая болезнь сердца, профилактика приступов стенокардии, стенокардия"},{"name":"Показания к применению","value":"Длительная терапия ишемической болезни сердца: профилактика приступов стабильной стенокардии в составе моно- или комбинированной терапии."},{"name":"Противопоказания","value":"- повышенная чувствительность к действующему веществу или любому из вспомогательных веществ, входящих в состав лекарственного препарата.\u003Cbr\u003E- болезнь Паркинсона, симптомы паркинсонизма, тремор, синдром \"беспокойных ног\" и другие, связанные с ними двигательные нарушения.\u003Cbr\u003E- тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин).\u003Cbr\u003E- из-за отсутствия достаточного количества клинических данных пациентам до 18 лет назначение лекарственного препарата не рекомендуется.\u003Cbr\u003E- беременность и период грудного вскармливания.\u003Cbr\u003E"},{"name":"Состав","value":"Состав на одну таблетку:\u003Cbr\u003Eдействующее вещество: триметазидина дигидрохлорид 35,0 мг;\u003Cbr\u003Eвспомогательные вещества: гипролоза (гидроксипропилцеллюлоза) 6,0 мг; гипромеллоза (гидроксипропилметилцеллюлоза) 69,4 мг; кальция гидрофосфат 29,2 мг; коповидон 4,2 мг; кремния диоксид коллоидный 6,4 мг; магния стеарат 0,8 мг; целлюлоза микрокристаллическая (тип 302) 64,4 мг;\u003Cbr\u003Eсостав оболочки: Селекоат AQ-01673 розовый 7,0 мг, в том числе: гипромеллоза (гидроксипропилметилцеллюлоза) 2,8 мг, макрогол-400 (полиэтиленгликоль-400) 0,7 мг, макрогол-6000 (полиэтиленгликоль-6000) 0,7 мг, титана диоксид 2,1 мг, краситель пунцовый [Понсо 4 R] 0,7 мг.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Триметазидин"},{"name":"Способ применения и дозы","value":"Таблетки Депренорм МВ следует принимать целиком, не разжевывая, запивая водой.\u003Cbr\u003EВнутрь, по 1 таблетке 2 раза в сутки, утром и вечером, во время еды.\u003Cbr\u003EОценка пользы от лечения должна быть проведена после трех месяцев приема препарата. Прием триметазидина следует прекратить, если за это время улучшение не наступило.\u003Cbr\u003EПродолжительность лечения определяется лечащим врачом.\u003Cbr\u003EОсобые группы\u003Cbr\u003EПациенты с нарушением функции почек\u003Cbr\u003EУ пациентов с умеренным нарушением функции почек (КК 30-60 мл/мин) суточная доза составляет 35 мг (1 таблетка), утром во время завтрака.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EУ пациентов пожилого возраста может наблюдаться повышенная экспозиция триметазидина из-за возрастного снижения функции почек (см. раздел \"Фармакологические свойства\"). У пациентов с умеренным нарушением функции почек (КК 30-60 мл/мин) рекомендованная суточная доза составляет 35 мг (1 таблетка), утром во время завтрака.\u003Cbr\u003EПодбор дозы у пациентов старше 75 лет должен происходить с осторожностью (см. раздел \"Особые указания\").\u003Cbr\u003E"},{"name":"Побочные действия","value":"Частота побочных эффектов, отмеченных при приеме триметазидина, приведена в следующей градации:\nочень часто (более 1/10);\nчасто (более 1/100, менее 1/10);\nнечасто (более 1/1000, менее 1/100);\nредко (более 1/10000, менее 1/1000);\nочень редко (менее 1/10000, в том числе отдельные сообщения);\nнеуточненной частоты (частота не может быть подсчитана по доступным данным).\u003Cbr\u003EСо стороны центральной нервной системы\nЧасто: головокружение, головная боль.\nНеуточненной частоты: симптомы паркинсонизма (тремор, акинезия, повышение тонуса), неустойчивость в позе Ромберга и «шаткость» походки, синдром «беспокойных» ног, другие связанные с ними двигательные нарушения, обычно обратимые после прекращения терапии. Нарушения сна (бессонница, сонливость).\nСо стороны сердечно-сосудистой системы\nРедко: ортостатическая гипотензия, «приливы» крови к коже лица, ощущение сердцебиения, экстрасистолия, тахикардия, выраженное снижение АД.\nСо стороны кровеносной и лимфатической системы\nНеуточненной частоты: агранулоцитоз, тромбоцитопения, тромбоцитопеническая пурпура.\nСо стороны пищеварительной системы\nЧасто: боль в животе, диарея, диспепсия, тошнота, рвота.\nНеуточненной частоты: запор.\nСо стороны печени и желчевыводящих путей\nНеуточненной частоты: гепатит.\nСо стороны кожных покровов\nЧасто: кожная сыпь, зуд, крапивница.\nНеуточненной частоты: острый генерализованный экзантематозныи пустулез, отек Квинке.\nОбщие нарушения\nЧасто: астения.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Триметазидин предотвращает снижение внутриклеточной концентрации аденозинтрифосфата (АТФ) путем сохранения энергетического метаболизма клеток в состоянии гипоксии. Таким образом, препарат обеспечивает нормальное функционирование мембранных ионных каналов, трансмембранный перенос ионов калия и натрия и сохранение клеточного гомеостаза.\u003Cbr\u003EТриметазидин ингибирует окисление жирных кислот за счет селективного ингибирования фермента З-кетоацил-КоА-тиолазы (З-КАТ) митохондриальной длинноцепочечной изоформы жирных кислот, что приводит к усилению окисления глюкозы и ускорению гликолиза с окислением глюкозы, что и обусловливает защиту миокарда от ишемии. Переключение энергетического метаболизма с окисления жирных кислот на окисление глюкозы лежит в основе фармакологических свойств триметазидина.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"антиангинальное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С, во вторичной упаковке (пачке картонной). Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Имеется лишь очень ограниченная информация о передозировке триметазидина. В случае передозировки следует проводить симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EДанные о применении триметазидина у беременных отсутствуют. Исследования на животных не выявили наличие прямого или непрямого негативного влияния в отношении репродуктивной функции.\u003Cbr\u003EПрименение препарата Депренорм MB во время беременности противопоказано.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EДанные о выделении или его метаболитов в грудное молоко отсутствуют. Риск для новорожденного/ребенка не может быть исключен. При необходимости применения лекарственного препарата Депренорм МВ в период лактации грудное вскармливание необходимо прекратить.\u003Cbr\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В ходе клинических исследований не было выявлено влияния триметазидина на показатели гемодинамики, однако в период пострегистрационного применения наблюдались случаи головокружения и сонливости (см. раздел «Побочное действие»), что может повлиять на способность к управлению автотранспортом и выполнение работ, требующих повышенной скорости физической и психической реакций."},{"name":"Особые указания","value":"С осторожностью:\nПациенты с умеренным нарушением функции почек (клиренс креатинина 30-60 мл/мин).\n\nПациенты старше 75 лет (см. разделы \"Способ применения и дозы\" и \"Особые указания\").\u003Cbr\u003EОсобые указания:\u003Cbr\u003EЛекарственный препарат Депренорм МВ не предназначен для купирования приступов стенокардии и не показан для начального курса терапии нестабильной стенокардии или инфаркта миокарда на догоспитальном этапе или в первые дни госпитализации.\u003Cbr\u003EВ случае развития приступа стенокардии следует вновь оценить степень поражения коронарных артерий и, при необходимости, адаптировать лечение (лекарственную терапию или возможное проведение процедуры реваскуляризации).\u003Cbr\u003EТриметазидин может вызывать или ухудшать симптомы паркинсонизма (тремор, акинезию, повышение тонуса), поэтому следует проводить регулярное наблюдение пациентов, особенно пожилого возраста. В сомнительных случаях пациенты должны быть направлены к неврологу для соответствующего обследования.\u003Cbr\u003EПри появлении двигательных нарушений, таких как симптомы паркинсонизма, синдром «беспокойных ног», тремор, неустойчивость походки, триметазидин следует окончательно отменить.\u003Cbr\u003EТакие случаи редки и симптомы обычно проходят после прекращения терапии: у большинства пациентов в течение 4 месяцев после отмены триметазидина. Если симптомы паркинсонизма сохраняются более 4 месяцев после отмены препарата, следует проконсультироваться у невролога.\u003Cbr\u003EМогут отмечаться случаи падения, связанные с неустойчивостью походки или артериальной гипотензией особенно у пациентов, принимающих гипотензивные препараты (см. раздел «Побочное действие»).\u003Cbr\u003EСледует с осторожностью назначать триметазидин пациентам, у которых возможно повышение его экспозиции:\u003Cbr\u003E- При нарушении функции почек умеренной степени тяжести (см. разделы «Фармакологические свойства» и «Способ применения и дозы»).\u003Cbr\u003E- У пожилых пациентов старше 75 лет (см. раздел «Способ применения и дозы»).\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Не было выявлено взаимодействий с другими лекарственными средствами."},{"name":"Регистрационный номер","value":"ЛС-001706"},{"name":"Дата государственной регистрации","value":"04.02.2021"},{"name":"Владелец регистрационного удостоверения","value":"Канонфарма продакшн"},{"name":"Изготовитель","value":"Канонфарма продакшн"},{"name":"Фасовщик","value":"Канонфарма продакшн"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Депренорм"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_11564566971353697772"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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Ещё может подойти

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Инструкция

Показания к применению

Длительная терапия ишемической болезни сердца: профилактика приступов стабильной стенокардии в составе моно- или комбинированной терапии.

Противопоказания

- повышенная чувствительность к действующему веществу или любому из вспомогательных веществ, входящих в состав лекарственного препарата.
- болезнь Паркинсона, симптомы паркинсонизма, тремор, синдром "беспокойных ног" и другие, связанные с ними двигательные нарушения.
- тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин).
- из-за отсутствия достаточного количества клинических данных пациентам до 18 лет назначение лекарственного препарата не рекомендуется.
- беременность и период грудного вскармливания.

Способ применения и дозы

Таблетки Депренорм МВ следует принимать целиком, не разжевывая, запивая водой.
Внутрь, по 1 таблетке 2 раза в сутки, утром и вечером, во время еды.
Оценка пользы от лечения должна быть проведена после трех месяцев приема препарата. Прием триметазидина следует прекратить, если за это время улучшение не наступило.
Продолжительность лечения определяется лечащим врачом.
Особые группы
Пациенты с нарушением функции почек
У пациентов с умеренным нарушением функции почек (КК 30-60 мл/мин) суточная доза составляет 35 мг (1 таблетка), утром во время завтрака.
Пациенты пожилого возраста
У пациентов пожилого возраста может наблюдаться повышенная экспозиция триметазидина из-за возрастного снижения функции почек (см. раздел "Фармакологические свойства"). У пациентов с умеренным нарушением функции почек (КК 30-60 мл/мин) рекомендованная суточная доза составляет 35 мг (1 таблетка), утром во время завтрака.
Подбор дозы у пациентов старше 75 лет должен происходить с осторожностью (см. раздел "Особые указания").
Полная инструкция
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Депренорм МВ таб. с пролонг. высвоб., п/о плен.
Депренорм МВ таб. с пролонг. высвоб., п/о плен., 35 мг, 60 шт.
5.0
(9)
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1 вопрос
Инструкция

461 ₽

Скидка: 10%
–10 %
Вместо:511 ₽
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5.0
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У продавца:9 оценок·2 отзыва
У всех продавцов:38 оценок·9 отзывов
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user avatar
10 месяцев назад • Лариса Мороз • Куплен на Маркете
Достоинства: все замечательно
user avatar
Год назад • Ольга И. • Куплен на Маркете
Достоинства: Цена
Недостатки: Нет
Посмотреть все отзывы на Маркете
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