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Описание

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Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 20 шт.

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4.8
(11)
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Количество штук в упаковке, шт.: 20

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Объем, мл: 2

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Коротко о товаре

Артикул Маркета
4453152270
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Строго контролируемых клинических исследований безопасности применения препарата Мексидол у детей, при беременности и кормлении грудью не проводилось."},{"name":"Состав","value":"Действующее вещество: этилметилгидроксипиридина сукцинат 50 г;\u003Cbr\u003Eвспомогательные вещества: натрия метабисульфит 0,4 мг, вода для инъекций до 1 мл."},{"name":"Действующее вещество","value":"Этилметилгидроксипиридина сукцинат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28710482"]}}},{"name":"Способ применения и дозы","value":"В/м или в/в (струйно или капельно). При инфузионном способе введения препарат следует разводить в 0,9% растворе натрия хлорида.\u003Cbr\u003EСтруйно Мексидол вводят медленно в течение 5-7 мин, капельно - со скоростью 40-60 капель в минуту. Максимальная суточная доза не должна превышать 1200 мг.\u003Cbr\u003EПри острых нарушениях мозгового кровообращения Мексидол применяют в первые 10-14 дней - в/в капельно по 200-500 мг 2-4 раза в сутки, затем в/м по 200-250 мг 2-3 раза в сутки в течение 2 недель.\u003Cbr\u003EПри черепно-мозговой травме и последствиях черепно-мозговых травм Мексидол применяют в течении 10-15 дней в/в капельно по 200-500 мг 2-4 раза в сутки.\u003Cbr\u003EПри дисциркуляторной энцефалопатии в фазе декомпенсации Мексидол следует назначать в/в струйно или капельно в дозе 200-500 мг 1- 2 раза в сутки на протяжении 14 дней. Затем в/м по 100-250 мг/сут. на протяжении последующих 2 нед.\u003Cbr\u003EДля курсовой профилактики дисциркуляторной энцефалопатии препарат вводят в/м в дозе 200-250 мг 2 раза в сутки на протяжении 10-14 дней.\u003Cbr\u003EПри легких когнитивных нарушениях у больных пожилого возраста и при тревожных расстройствах препарат применяют в/м в суточной дозе 100-300 мг/сут на протяжении 14-30 дней.\u003Cbr\u003EПри остром инфаркте миокарда в составе комплексной терапии Мексидол вводят внутривенно или внутримышечно в течение 14 суток, на фоне традиционной терапии инфаркта миокарда, включающей нитраты, бета-адреноблокаторы, ингибиторы ангиотензинпревращающего фермента (АПФ), тромболитики, антикоагулянтные и антиагрегантные средства, а также симптоматические средства по показаниям.\u003Cbr\u003EВ первые 5 суток для достижения максимального эффекта препарат желательно вводить внутривенно, в последующие 9 суток Мексидол может вводиться внутримышечно. Внутривенное введение препарата производят путем капельной инфузии, медленно (во избежание побочных эффектов) на 0,9% растворе натрия хлорида или 5% растворе декстрозы (глюкозы) в объеме 100-150 мл в течение 30-90 мин. При необходимости возможно медленное струйное введение препарата, продолжительностью не менее 5 минут.\u003Cbr\u003EВведение препарата (внутривенное или внутримышечное) осуществляют 3 раза в сутки, через каждые 8 часов. Суточная терапевтическая доза составляет 6-9 мг/кг массы тела в сутки, разовая доза - 2-3 мг/кг массы тела. Максимальная суточная доза не должна превышать 800 мг, разовая - 250 мг.\u003Cbr\u003EПри открытоугольной глаукоме различных стадий в составе комплексной терапии Мексидол вводят внутримышечно по 100-300 мг/сутки, 1-3 раза в сутки в течение 14 дней.\u003Cbr\u003EПри абстинентном алкогольном синдроме Мексидол вводят в дозе 200-500 мг в/в капельно или в/м 2-3 раза в сутки в сутки в течение 5-7 дней.\u003Cbr\u003EПри острой интоксикации антипсихотическими средствами препарат вводят в/в в дозе 200-500 мг/сут на протяжении 7-14 дней.\u003Cbr\u003EПри острых гнойно-воспалительных процессах брюшной полости (острый некротический панкреатит, перитонит) препарат назначают в первые сутки как в предоперационном, так и в послеоперационном периоде. Вводимые дозы зависят от формы и тяжести заболевания, распространенности процесса, вариантов клинического течения. Отмена препарата должна производиться постепенно только после устойчивого положительного клинико-лабораторного эффекта.\u003Cbr\u003EПри остром отечном (интерстициальном) панкреатите Мексидол назначают по 200-500 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида) и в/м.\u003Cbr\u003EЛегкая степень тяжести некротического панкреатита - по 100-200 мг 3 раза в день в/в капельно (в 0,9% растворе натрия хлорида) и в/м.\u003Cbr\u003EСредняя степень тяжести - по 200 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида).\u003Cbr\u003EТяжелое течение - в пульс- дозировке 800 мг в первые сутки, при двукратном режиме введения; далее по 200-500 мг 2 раза в день с постепенным снижением суточной дозы.\u003Cbr\u003EКрайне тяжелое течение - в начальной дозировке 800 мг/сут до стойкого купирования проявлений панкреатогенного шока, по стабилизации состояния по 300-500 мг 2 раза в день в/в капельно (в 0,9% растворе натрия хлорида) с постепенным снижением суточной дозировки."},{"name":"Побочные действия","value":"Во избежание возникновения побочных эффектов рекомендуется соблюдать режим дозирования и скорость введения препарата. Частота побочных эффектов определялась в соответствии с классификацией Всемирной организации здравоохранения (ВОЗ): очень часто (≥10%); часто ( ≥2%,но \u003C 10%); нечасто (≥ 0,1%, но \u003C 1%); редко (≥ 0,01%, но \u003C 0,1%); очень редко (\u003C 0,01%); частота неизвестна (частота не может быть определена на основе имеющихся данных).\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eочень редко анафилактический шок, ангионевротический отек, крапивница.\u003Cbr\u003EПсихические нарушения:\u003Cbr\u003Eочень редко сонливость.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eочень редко головная боль,головокружение (может быть связано с чрезмерно высокой скоростью введения и носит кратковременный характер)\u003Cbr\u003EНарушения со стороны сосудов:\u003Cbr\u003Eочень редко понижение АД, повышение АД (может быть связано с чрезмерно высокой скоростью введения и носит кратковременный характер).\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения:\u003Cbr\u003Eочень редко - сухой кашель, першение в горле, дискомфорт в грудной клетке, затруднение дыхания (может быть связано с чрезмерно высокой скоростью введения и носит кратковременный характер)\u003Cbr\u003EЖелудочно-кишечные нарушения:\u003Cbr\u003Eочень редко - сухость во рту, тошнота, ощущение неприятного запаха, металлический привкус во рту\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: очень редко - зуд, сыпь, гиперемия.\u003Cbr\u003EОбщие нарушения и реакции в месте введения:\u003Cbr\u003Eочень редко - ощущение тепла."},{"name":"Фармакологическое действие","value":"Оказывает антигипоксическое, мембранопротекторное, ноотропное, противосудорожное, анксиолитическое действие, повышает устойчивость организма к стрессу. Препарат повышает резистентность организма к воздействию основных повреждающих факторов, к кислородзависимым патологическим состояниям (шок, гипоксия и ишемия, нарушение мозгового кровообращения, интоксикация алкоголем и антипсихотическими препаратами (нейролептиками)).\u003Cbr\u003EМексидол улучшает мозговой метаболизм и кровоснабжение головного мозга, улучшает микроциркуляцию и реологические свойства крови, уменьшает агрегацию тромбоцитов. Стабилизирует мембранные структуры клеток крови (эритроциты и тромбоциты) при гемолизе. Оказывает гиполипидемическое действие, уменьшает уровень общего холестерина и ЛПНП.\u003Cbr\u003EУменьшает ферментативную токсемию и эндогенную интоксикацию при остром панкреатите.\u003Cbr\u003EМеханизм действия Мексидола обусловлен его антигипоксантным, антиоксидантным и мембранопротекторным действием. Он ингибирует процессы перекисного окисления липидов, повышает активность супероксиддисмутазы, повышает соотношение липид-белок, уменьшает вязкость мембраны, увеличивает ее текучесть. Модулирует активность мембраносвязанных ферментов (кальцийнезависимая фосфодиэстераза, аденилатциклаза, ацетилхолинэстераза), рецепторных комплексов (бензодиазепиновый, ГАМК, ацетилхолиновый), что усиливает их способность связывания с лигандами, помогает сохранению структурно-функциональной организации биомембран, транспорта нейромедиаторов и улучшению синаптической передачи. Мексидол повышает содержание дофамина в головном мозге. Вызывает усиление компенсаторной активности аэробного гликолиза и снижение степени угнетения окислительных процессов в цикле Кребса в условиях гипоксии, с увеличением содержания АТФ, креатинфосфата и активацией энергосинтезирующих функций митохондрий, стабилизацию клеточных мембран. Мексидол нормализует метаболические процессы в ишемизированном миокарде, уменьшает зону некроза, восстанавливает и улучшает электрическую активность и сократимость миокарда, а также увеличивает коронарный кровоток в зоне ишемии, уменьшает последствия реперфузионного синдрома при острой коронарной недостаточности. Повышает антиангинальную активность нитропрепаратов. Мексидол способствует сохранению ганглиозных клеток сетчатки и волокон зрительного нерва при прогрессирующей нейропатии, причинами которой являются хроническая ишемия и гипоксия. Улучшает функциональную активность сетчатки и зрительного нерва, увеличивая остроту зрения."},{"name":"Фармакологическая группа","value":"антиоксидантное средство"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763748"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить в сухом защищённом от света недоступном для детей месте при температуре не выше 25°С."},{"name":"Передозировка","value":"Симптомы: сонливость, бессонница.\u003Cbr\u003EЛечение: в связи с низкой токсичностью передозировка маловероятна. Лечение, как правило, не требуется, симптомы исчезают самостоятельно в течение суток. При выраженных проявлениях проводится поддерживающее и симптоматическое лечение."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Мексидол противопоказан при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период приема препарата следует соблюдать осторожность при работе, требующей быстроты психофизических реакций (управление транспортными средствами, механизмами и т.п.)."},{"name":"Особые указания","value":"В отдельных случаях, особенно у предрасположенных пациентов с бронхиальной астмой при повышенной чувствительности к сульфитам, возможно развитие тяжелых реакций гиперчувствительности."},{"name":"Взаимодействие","value":"Усиливает действие бензодиазепиновых анксиолитиков, противосудорожных средств (карбамазепина), противопаркинсонических средств (леводопа).\u003Cbr\u003EУменьшает токсические эффекты этилового спирта."},{"name":"Регистрационный номер","value":"Р N002161/01"},{"name":"Дата государственной регистрации","value":"13.01.2020"},{"name":"Владелец регистрационного удостоверения","value":"Фармасофт","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:12531373"]}}},{"name":"Изготовитель","value":"Армавирская биофабрика"},{"name":"Фасовщик","value":"Армавирская биофабрика"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мексидол","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18007914"]}}},{"name":"Срок годности","value":"37 мес."}]}},"fullSpecsGrouped":{"18206994572697024951":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"головной мозг, кровеносные сосуды"},{"name":"Назначение","value":"дисциркуляторная энцефалопатия, нарушение когнитивной функции, острые нарушения мозгового кровообращения, синдром вегетативной (нейроциркуляторной) дистонии"},{"name":"Показания к применению","value":"Острые нарушения мозгового кровообращения;\u003Cbr\u003E- черепно-мозговая травма, последствия черепно-мозговых травм;\u003Cbr\u003E- дисциркуляторная энцефалопатия;\u003Cbr\u003E- синдром вегетативной дистонии;\u003Cbr\u003E- легкие когнитивные расстройства атеросклеротического генеза;\u003Cbr\u003E- тревожные расстройства при невротических и неврозоподобных состояниях;\u003Cbr\u003E- острый инфаркт миокарда (с первых суток) в составе комплексной терапии;\u003Cbr\u003E- первичная открытоугольная глаукома различных стадий, в составе комплексной терапии;\u003Cbr\u003E- купирование абстинентного синдрома при алкоголизме с преобладанием неврозоподобных и вегетативно-сосудистых расстройств;\u003Cbr\u003E- острая интоксикация антипсихотическими средствами;\u003Cbr\u003E- острые гнойно-воспалительные процессы брюшной полости (острый некротический панкреатит, перитонит) в составе комплексной терапии."},{"name":"Противопоказания","value":"Острые нарушения функции печени и почек, повышенная индивидуальная чувствительность к препарату. Строго контролируемых клинических исследований безопасности применения препарата Мексидол у детей, при беременности и кормлении грудью не проводилось."},{"name":"Состав","value":"Действующее вещество: этилметилгидроксипиридина сукцинат 50 г;\u003Cbr\u003Eвспомогательные вещества: натрия метабисульфит 0,4 мг, вода для инъекций до 1 мл."},{"name":"Действующее вещество","value":"Этилметилгидроксипиридина сукцинат"},{"name":"Способ применения и дозы","value":"В/м или в/в (струйно или капельно). При инфузионном способе введения препарат следует разводить в 0,9% растворе натрия хлорида.\u003Cbr\u003EСтруйно Мексидол вводят медленно в течение 5-7 мин, капельно - со скоростью 40-60 капель в минуту. Максимальная суточная доза не должна превышать 1200 мг.\u003Cbr\u003EПри острых нарушениях мозгового кровообращения Мексидол применяют в первые 10-14 дней - в/в капельно по 200-500 мг 2-4 раза в сутки, затем в/м по 200-250 мг 2-3 раза в сутки в течение 2 недель.\u003Cbr\u003EПри черепно-мозговой травме и последствиях черепно-мозговых травм Мексидол применяют в течении 10-15 дней в/в капельно по 200-500 мг 2-4 раза в сутки.\u003Cbr\u003EПри дисциркуляторной энцефалопатии в фазе декомпенсации Мексидол следует назначать в/в струйно или капельно в дозе 200-500 мг 1- 2 раза в сутки на протяжении 14 дней. Затем в/м по 100-250 мг/сут. на протяжении последующих 2 нед.\u003Cbr\u003EДля курсовой профилактики дисциркуляторной энцефалопатии препарат вводят в/м в дозе 200-250 мг 2 раза в сутки на протяжении 10-14 дней.\u003Cbr\u003EПри легких когнитивных нарушениях у больных пожилого возраста и при тревожных расстройствах препарат применяют в/м в суточной дозе 100-300 мг/сут на протяжении 14-30 дней.\u003Cbr\u003EПри остром инфаркте миокарда в составе комплексной терапии Мексидол вводят внутривенно или внутримышечно в течение 14 суток, на фоне традиционной терапии инфаркта миокарда, включающей нитраты, бета-адреноблокаторы, ингибиторы ангиотензинпревращающего фермента (АПФ), тромболитики, антикоагулянтные и антиагрегантные средства, а также симптоматические средства по показаниям.\u003Cbr\u003EВ первые 5 суток для достижения максимального эффекта препарат желательно вводить внутривенно, в последующие 9 суток Мексидол может вводиться внутримышечно. Внутривенное введение препарата производят путем капельной инфузии, медленно (во избежание побочных эффектов) на 0,9% растворе натрия хлорида или 5% растворе декстрозы (глюкозы) в объеме 100-150 мл в течение 30-90 мин. При необходимости возможно медленное струйное введение препарата, продолжительностью не менее 5 минут.\u003Cbr\u003EВведение препарата (внутривенное или внутримышечное) осуществляют 3 раза в сутки, через каждые 8 часов. Суточная терапевтическая доза составляет 6-9 мг/кг массы тела в сутки, разовая доза - 2-3 мг/кг массы тела. Максимальная суточная доза не должна превышать 800 мг, разовая - 250 мг.\u003Cbr\u003EПри открытоугольной глаукоме различных стадий в составе комплексной терапии Мексидол вводят внутримышечно по 100-300 мг/сутки, 1-3 раза в сутки в течение 14 дней.\u003Cbr\u003EПри абстинентном алкогольном синдроме Мексидол вводят в дозе 200-500 мг в/в капельно или в/м 2-3 раза в сутки в сутки в течение 5-7 дней.\u003Cbr\u003EПри острой интоксикации антипсихотическими средствами препарат вводят в/в в дозе 200-500 мг/сут на протяжении 7-14 дней.\u003Cbr\u003EПри острых гнойно-воспалительных процессах брюшной полости (острый некротический панкреатит, перитонит) препарат назначают в первые сутки как в предоперационном, так и в послеоперационном периоде. Вводимые дозы зависят от формы и тяжести заболевания, распространенности процесса, вариантов клинического течения. Отмена препарата должна производиться постепенно только после устойчивого положительного клинико-лабораторного эффекта.\u003Cbr\u003EПри остром отечном (интерстициальном) панкреатите Мексидол назначают по 200-500 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида) и в/м.\u003Cbr\u003EЛегкая степень тяжести некротического панкреатита - по 100-200 мг 3 раза в день в/в капельно (в 0,9% растворе натрия хлорида) и в/м.\u003Cbr\u003EСредняя степень тяжести - по 200 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида).\u003Cbr\u003EТяжелое течение - в пульс- дозировке 800 мг в первые сутки, при двукратном режиме введения; далее по 200-500 мг 2 раза в день с постепенным снижением суточной дозы.\u003Cbr\u003EКрайне тяжелое течение - в начальной дозировке 800 мг/сут до стойкого купирования проявлений панкреатогенного шока, по стабилизации состояния по 300-500 мг 2 раза в день в/в капельно (в 0,9% растворе натрия хлорида) с постепенным снижением суточной дозировки."},{"name":"Побочные действия","value":"Во избежание возникновения побочных эффектов рекомендуется соблюдать режим дозирования и скорость введения препарата. Частота побочных эффектов определялась в соответствии с классификацией Всемирной организации здравоохранения (ВОЗ): очень часто (≥10%); часто ( ≥2%,но \u003C 10%); нечасто (≥ 0,1%, но \u003C 1%); редко (≥ 0,01%, но \u003C 0,1%); очень редко (\u003C 0,01%); частота неизвестна (частота не может быть определена на основе имеющихся данных).\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eочень редко анафилактический шок, ангионевротический отек, крапивница.\u003Cbr\u003EПсихические нарушения:\u003Cbr\u003Eочень редко сонливость.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eочень редко головная боль,головокружение (может быть связано с чрезмерно высокой скоростью введения и носит кратковременный характер)\u003Cbr\u003EНарушения со стороны сосудов:\u003Cbr\u003Eочень редко понижение АД, повышение АД (может быть связано с чрезмерно высокой скоростью введения и носит кратковременный характер).\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения:\u003Cbr\u003Eочень редко - сухой кашель, першение в горле, дискомфорт в грудной клетке, затруднение дыхания (может быть связано с чрезмерно высокой скоростью введения и носит кратковременный характер)\u003Cbr\u003EЖелудочно-кишечные нарушения:\u003Cbr\u003Eочень редко - сухость во рту, тошнота, ощущение неприятного запаха, металлический привкус во рту\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: очень редко - зуд, сыпь, гиперемия.\u003Cbr\u003EОбщие нарушения и реакции в месте введения:\u003Cbr\u003Eочень редко - ощущение тепла."},{"name":"Фармакологическое действие","value":"Оказывает антигипоксическое, мембранопротекторное, ноотропное, противосудорожное, анксиолитическое действие, повышает устойчивость организма к стрессу. Препарат повышает резистентность организма к воздействию основных повреждающих факторов, к кислородзависимым патологическим состояниям (шок, гипоксия и ишемия, нарушение мозгового кровообращения, интоксикация алкоголем и антипсихотическими препаратами (нейролептиками)).\u003Cbr\u003EМексидол улучшает мозговой метаболизм и кровоснабжение головного мозга, улучшает микроциркуляцию и реологические свойства крови, уменьшает агрегацию тромбоцитов. Стабилизирует мембранные структуры клеток крови (эритроциты и тромбоциты) при гемолизе. Оказывает гиполипидемическое действие, уменьшает уровень общего холестерина и ЛПНП.\u003Cbr\u003EУменьшает ферментативную токсемию и эндогенную интоксикацию при остром панкреатите.\u003Cbr\u003EМеханизм действия Мексидола обусловлен его антигипоксантным, антиоксидантным и мембранопротекторным действием. Он ингибирует процессы перекисного окисления липидов, повышает активность супероксиддисмутазы, повышает соотношение липид-белок, уменьшает вязкость мембраны, увеличивает ее текучесть. Модулирует активность мембраносвязанных ферментов (кальцийнезависимая фосфодиэстераза, аденилатциклаза, ацетилхолинэстераза), рецепторных комплексов (бензодиазепиновый, ГАМК, ацетилхолиновый), что усиливает их способность связывания с лигандами, помогает сохранению структурно-функциональной организации биомембран, транспорта нейромедиаторов и улучшению синаптической передачи. Мексидол повышает содержание дофамина в головном мозге. Вызывает усиление компенсаторной активности аэробного гликолиза и снижение степени угнетения окислительных процессов в цикле Кребса в условиях гипоксии, с увеличением содержания АТФ, креатинфосфата и активацией энергосинтезирующих функций митохондрий, стабилизацию клеточных мембран. Мексидол нормализует метаболические процессы в ишемизированном миокарде, уменьшает зону некроза, восстанавливает и улучшает электрическую активность и сократимость миокарда, а также увеличивает коронарный кровоток в зоне ишемии, уменьшает последствия реперфузионного синдрома при острой коронарной недостаточности. Повышает антиангинальную активность нитропрепаратов. Мексидол способствует сохранению ганглиозных клеток сетчатки и волокон зрительного нерва при прогрессирующей нейропатии, причинами которой являются хроническая ишемия и гипоксия. Улучшает функциональную активность сетчатки и зрительного нерва, увеличивая остроту зрения."},{"name":"Фармакологическая группа","value":"антиоксидантное средство"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить в сухом защищённом от света недоступном для детей месте при температуре не выше 25°С."},{"name":"Передозировка","value":"Симптомы: сонливость, бессонница.\u003Cbr\u003EЛечение: в связи с низкой токсичностью передозировка маловероятна. Лечение, как правило, не требуется, симптомы исчезают самостоятельно в течение суток. При выраженных проявлениях проводится поддерживающее и симптоматическое лечение."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Мексидол противопоказан при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период приема препарата следует соблюдать осторожность при работе, требующей быстроты психофизических реакций (управление транспортными средствами, механизмами и т.п.)."},{"name":"Особые указания","value":"В отдельных случаях, особенно у предрасположенных пациентов с бронхиальной астмой при повышенной чувствительности к сульфитам, возможно развитие тяжелых реакций гиперчувствительности."},{"name":"Взаимодействие","value":"Усиливает действие бензодиазепиновых анксиолитиков, противосудорожных средств (карбамазепина), противопаркинсонических средств (леводопа).\u003Cbr\u003EУменьшает токсические эффекты этилового спирта."},{"name":"Регистрационный номер","value":"Р N002161/01"},{"name":"Дата государственной регистрации","value":"13.01.2020"},{"name":"Владелец регистрационного удостоверения","value":"Фармасофт"},{"name":"Изготовитель","value":"Армавирская биофабрика"},{"name":"Фасовщик","value":"Армавирская биофабрика"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мексидол"},{"name":"Срок годности","value":"37 мес."}]}],"transitionId":"tr_17824000841424999331"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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1 013 ₽

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  • Мексидол таб. п/о плен., 125 мг, 30 шт.
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    Мексидол таб. п/о плен., 125 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 62 оценки
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  • Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 5 мл, 5 шт.
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    Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 5 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 531 ₽
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  • Мексидол р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.
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    Мексидол р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 4.4 из 5
    на основе 14 оценок
    Цена 579 ₽
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  • Мексидол форте таб. п/о. плен., 250 мг, 40 шт.
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    Мексидол форте таб. п/о. плен., 250 мг, 40 шт.

    Рейтинг товара: 4.8 из 5
    на основе 70 оценок
    Цена 717 ₽
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  • Кортексин лиоф. д/приг. р-ра для в/м введ. фл., 10 мг, 0.22 г, 10 шт.
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    Кортексин лиоф. д/приг. р-ра для в/м введ. фл., 10 мг, 0.22 г, 10 шт.

    Рейтинг товара: 4.8 из 5
    на основе 51 оценка
    Цена 1 707 ₽
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  • Церебролизин р-р д/ин. амп., 5 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-w36zbpznd8q/toggleWishlist":{"skuId":"228004469","productId":1404748442,"offerId":"FUAKyYbGPMkFOA-oQc5k1w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ4uyt09qU9twaEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUImoXrnQUQ9aTcbBjh4NAHIO3ZwQc=","sign":"21JjP3IhxJq1n0eHwKKV4JMSmSaBzQDbBqo7t/SlBbA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-w36zbpznd8q/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Церебролизин р-р д/ин. амп., 5 мл, 5 шт.

    Рейтинг товара: 4.9 из 5
    на основе 18 оценок
    Цена 1 049 ₽
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  • Мексиприм р-р д/в-в и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.
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    Мексиприм р-р д/в-в и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 436 ₽
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  • Мексифин р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cvsyqk2gb05/toggleWishlist":{"skuId":"832382522","productId":1404748415,"offerId":"qTLxyk5P7wXPRgpdAYxu8Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ4uyt09qU9twaEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI/4TrnQUQusz0jAMYlsGQESDt2cEH","sign":"X5Ko/P17HqywHlyUyAp3M7cs5c0v7eYWT0rfo//CNDc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cvsyqk2gb05/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мексифин р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 3.4 из 5
    на основе 8 оценок
    Цена 315 ₽
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  • Кортексин лиоф. д/приг. р-ра для в/м введ. фл. (для детей), 5 мг, 10 шт.
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    Кортексин лиоф. д/приг. р-ра для в/м введ. фл. (для детей), 5 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 1 030 ₽
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  • Фенибут таб., 250 мг, 10 шт.
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    Фенибут таб., 250 мг, 10 шт.

    Рейтинг товара: 4.8 из 5
    на основе 324 оценки
    Цена 92 ₽
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  • Мексиприм таб. п/о плен., 125 мг, 30 шт.
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    Мексиприм таб. п/о плен., 125 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 7 оценок
    Цена 218 ₽
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  • Мексиприм р-р для в/в введ. и в/м введ., 50 мг/мл, 5 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-0gu2l0g20h2/toggleWishlist":{"skuId":"186923153","productId":1404748436,"offerId":"-r417muekz7GeBNBfY3IbA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ4uyt09qU9twaEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIlIXrnQUQkfGQWRjZ8c8GIO3ZwQc=","sign":"Zg2x0HNAbKHvRPwNFKrj/z5yis+Amn2J+H0tlN4oSkc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-0gu2l0g20h2/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мексиприм р-р для в/в введ. и в/м введ., 50 мг/мл, 5 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 16 оценок
    Цена 474 ₽
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Инструкция

Показания к применению

Острые нарушения мозгового кровообращения;
- черепно-мозговая травма, последствия черепно-мозговых травм;
- дисциркуляторная энцефалопатия;
- синдром вегетативной дистонии;
- легкие когнитивные расстройства атеросклеротического генеза;
- тревожные расстройства при невротических и неврозоподобных состояниях;
- острый инфаркт миокарда (с первых суток) в составе комплексной терапии;
- первичная открытоугольная глаукома различных стадий, в составе комплексной терапии;
- купирование абстинентного синдрома при алкоголизме с преобладанием неврозоподобных и вегетативно-сосудистых расстройств;
- острая интоксикация антипсихотическими средствами;
- острые гнойно-воспалительные процессы брюшной полости (острый некротический панкреатит, перитонит) в составе комплексной терапии.

Противопоказания

Острые нарушения функции печени и почек, повышенная индивидуальная чувствительность к препарату. Строго контролируемых клинических исследований безопасности применения препарата Мексидол у детей, при беременности и кормлении грудью не проводилось.

Способ применения и дозы

В/м или в/в (струйно или капельно). При инфузионном способе введения препарат следует разводить в 0,9% растворе натрия хлорида.
Струйно Мексидол вводят медленно в течение 5-7 мин, капельно - со скоростью 40-60 капель в минуту. Максимальная суточная доза не должна превышать 1200 мг.
При острых нарушениях мозгового кровообращения Мексидол применяют в первые 10-14 дней - в/в капельно по 200-500 мг 2-4 раза в сутки, затем в/м по 200-250 мг 2-3 раза в сутки в течение 2 недель.
При черепно-мозговой травме и последствиях черепно-мозговых травм Мексидол применяют в течении 10-15 дней в/в капельно по 200-500 мг 2-4 раза в сутки.
При дисциркуляторной энцефалопатии в фазе декомпенсации Мексидол следует назначать в/в струйно или капельно в дозе 200-500 мг 1- 2 раза в сутки на протяжении 14 дней. Затем в/м по 100-250 мг/сут. на протяжении последующих 2 нед.
Для курсовой профилактики дисциркуляторной энцефалопатии препарат вводят в/м в дозе 200-250 мг 2 раза в сутки на протяжении 10-14 дней.
При легких когнитивных нарушениях у больных пожилого возраста и при тревожных расстройствах препарат применяют в/м в суточной дозе 100-300 мг/сут на протяжении 14-30 дней.
При остром инфаркте миокарда в составе комплексной терапии Мексидол вводят внутривенно или внутримышечно в течение 14 суток, на фоне традиционной терапии инфаркта миокарда, включающей нитраты, бета-адреноблокаторы, ингибиторы ангиотензинпревращающего фермента (АПФ), тромболитики, антикоагулянтные и антиагрегантные средства, а также симптоматические средства по показаниям.
В первые 5 суток для достижения максимального эффекта препарат желательно вводить внутривенно, в последующие 9 суток Мексидол может вводиться внутримышечно. Внутривенное введение препарата производят путем капельной инфузии, медленно (во избежание побочных эффектов) на 0,9% растворе натрия хлорида или 5% растворе декстрозы (глюкозы) в объеме 100-150 мл в течение 30-90 мин. При необходимости возможно медленное струйное введение препарата, продолжительностью не менее 5 минут.
Введение препарата (внутривенное или внутримышечное) осуществляют 3 раза в сутки, через каждые 8 часов. Суточная терапевтическая доза составляет 6-9 мг/кг массы тела в сутки, разовая доза - 2-3 мг/кг массы тела. Максимальная суточная доза не должна превышать 800 мг, разовая - 250 мг.
При открытоугольной глаукоме различных стадий в составе комплексной терапии Мексидол вводят внутримышечно по 100-300 мг/сутки, 1-3 раза в сутки в течение 14 дней.
При абстинентном алкогольном синдроме Мексидол вводят в дозе 200-500 мг в/в капельно или в/м 2-3 раза в сутки в сутки в течение 5-7 дней.
При острой интоксикации антипсихотическими средствами препарат вводят в/в в дозе 200-500 мг/сут на протяжении 7-14 дней.
При острых гнойно-воспалительных процессах брюшной полости (острый некротический панкреатит, перитонит) препарат назначают в первые сутки как в предоперационном, так и в послеоперационном периоде. Вводимые дозы зависят от формы и тяжести заболевания, распространенности процесса, вариантов клинического течения. Отмена препарата должна производиться постепенно только после устойчивого положительного клинико-лабораторного эффекта.
При остром отечном (интерстициальном) панкреатите Мексидол назначают по 200-500 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида) и в/м.
Легкая степень тяжести некротического панкреатита - по 100-200 мг 3 раза в день в/в капельно (в 0,9% растворе натрия хлорида) и в/м.
Средняя степень тяжести - по 200 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида).
Тяжелое течение - в пульс- дозировке 800 мг в первые сутки, при двукратном режиме введения; далее по 200-500 мг 2 раза в день с постепенным снижением суточной дозы.
Крайне тяжелое течение - в начальной дозировке 800 мг/сут до стойкого купирования проявлений панкреатогенного шока, по стабилизации состояния по 300-500 мг 2 раза в день в/в капельно (в 0,9% растворе натрия хлорида) с постепенным снижением суточной дозировки.
Полная инструкция
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Мексидол р-р для в/в и в/м введ. амп.
Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 20 шт.
4.8
(11)
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10 вопросов
Инструкция

1 013 ₽

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4.8
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У продавца:11 оценок·3 отзыва
У всех продавцов:230 оценок·69 отзывов
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Месяц назад • Ольга Ефремова • Куплен на Маркете
Достоинства: одни достоинств! работает по назначению!
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2 месяца назад • Имя скрыто • Куплен на Маркете
Достоинства: это хороший препарат, но странно оценивать по предложенным критериям)
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Месяц назад • Имя скрыто • Куплен на Маркете
Достоинства: все ок
Посмотреть все отзывы на Маркете
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