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Описание

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Гроприносин-Рихтер сироп фл., 50 мг/мл, 150 мл

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Коротко о товаре

Артикул Маркета
3123938829
Тип препарата
Назначение
Действующее вещество
Возраст
от 3 лет
Инструкция
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препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"дыхательная система, кожа","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["34045610:34516012,34515990"]}}},{"name":"Назначение","value":"ОРВИ, генитальный герпес, герпес, инфекции кожи и слизистых оболочек, вызванные вирусом герпеса, инфекционный мононуклеоз, контагиозный моллюск, корь, лечение гриппа, лечение инфекций, вызванных вирусом простого герпеса (ВПГ), лечение офтальмического опоясывающего герпеса, опоясывающий герпес (лишай), папилломавирусная инфекция, подострый склерозирующий панэнцефалит, укрепление иммунитета, цитомегаловирусная инфекция","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["36476390:36619114,36619054,36619042,36618932,36618905,36618844,36618658,36618536,36618504,36617891,36617679,36617669,36617578,36617555,36617262"]}}},{"name":"Показания к применению","value":"- Грипп и острые респираторные вирусные инфекции.\u003Cbr\u003E- Инфекции, вызванные вирусом простого герпеса 1, 2, 3 и 4 типов: генитальный и лабиальный герпес, герпетический кератит, опоясывающий лишай, ветряная оспа, инфекционный мононуклеоз, вызванный вирусом Эпштейна-Барр.\u003Cbr\u003E- Цитомегаловирусная инфекция.\u003Cbr\u003E- Корь тяжёлого течения.\u003Cbr\u003E- Папилломавирусная инфекция: папилломы гортани и голосовых связок (фиброзного типа), генитальные папилломавирусные инфекции у мужчин и женщин, бородавки.\u003Cbr\u003E- Подострый склерозирующий панэнцефалит.\u003Cbr\u003E- Контагиозный моллюск."},{"name":"Противопоказания","value":"- Повышенная чувствительность к инозину пранобексу и другим компонентам препарата.\u003Cbr\u003E- Подагра.\u003Cbr\u003E- Мочекаменная болезнь.\u003Cbr\u003E- Аритмии.\u003Cbr\u003E- Хроническая почечная недостаточность.\u003Cbr\u003E- Детский возраст до 3 лет (масса тела до 15-20 кг).\u003Cbr\u003E- Беременность и период грудного вскармливания.\u003Cbr\u003E- Дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EСледует соблюдать осторожность при одновременном назначении с ингибиторами ксантиноксидазы, диуретиками, зидовудином, при острой печеночной недостаточности."},{"name":"Состав","value":"1 мл содержит:\u003Cbr\u003EДействующее вещество: Инозин Пранобекс - 50,00 мг.\u003Cbr\u003EВспомогательные вещества: метилпарагидроксибензоат, пропилпарагидроксибензоат, сахароза, натрия гидроксид, лимонная кислота, вода."},{"name":"Действующее вещество","value":"Инозин Пранобекс","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["27144131:28710302"]}}},{"name":"Способ применения и дозы","value":"Способ применения\u003Cbr\u003EВнутрь после еды. Для правильного дозирования прилагается мерный шприц для приёма препарата внутрь.\u003Cbr\u003EДозы\u003Cbr\u003EДоза препарата зависит от массы тела пациента и заболевания. Суточную дозу разделяют на несколько частей (3-4), которые следует принимать через равные промежутки времени в течение дня. Продолжительность лечения обычно составляет 5-14 дней. Приём препарата следует продолжить в течение 1-2 дней после исчезновения симптомов.\u003Cbr\u003EРекомендуемая суточная доза для взрослых и пожилых пациентов, а также детей 3 лет и старше (масса тела больше 15-20 кг) составляет 50 мг/кг массы тела в 3-4 приёма. 1 мл препарата Гроприносин-Рихтер содержит 50 мг инозина пранобекса.\u003Cbr\u003EДля лечения тяжёлых инфекций дозу можно индивидуально увеличивать до 100 мг/кг массы тела 4-6 раз в сутки. Максимальная суточная доза для взрослых составляет 3-4 г/сут (60-80 мл/сут).\u003Cbr\u003EМаксимальная суточная доза для детей от 3 лет и старше - 50 мг/кг/сут.\u003Cbr\u003EПродолжительность лечения\u003Cbr\u003EОстрые инфекции: продолжительность лечения у взрослых и детей обычно от 5 до 14 дней. Лечение следует продолжать до момента исчезновения клинических симптомов и в течение ещё 1-2 дней после исчезновения симптомов. При необходимости длительность лечения может быть увеличена индивидуально под контролем врача.\u003Cbr\u003EХронические рецидивирующие инфекции: у взрослых и детей лечение необходимо продолжать несколькими курсами по 5-10 дней с интервалом 8 дней. При проведении поддерживающей терапии доза может быть снижена до 500-1000 мг в сутки (10-20 мл/сут) в течение 30 дней.\u003Cbr\u003EГерпетические инфекции: лечение продолжается в течение 5-10 дней до исчезновения симптомов заболевания. Для уменьшения числа рецидивов в бессимптомный период препарат назначают по 500 мг 2 раза в сутки (20 мл/сут) в течение 30 дней.\u003Cbr\u003EПапилломавирусные инфекции: в качестве монотерапии препарат назначается на протяжении 14-28 дней взрослым в дозе 1000 мг 3 раза в сутки (60 мл/сут), детям - 250 мг на 5 кг массы тела (1 мл/кг/сут) 3-4 раза в сутки.\u003Cbr\u003EРецидивирующие остроконечные кондиломы: в качестве монотерапии или в комбинации с хирургическим лечением препарат назначается взрослым в дозе 1000 мг 3 раза в сутки (60 мл/сут), детям - в дозе 250 мг на 5 кг массы тела (1 мл/кг/сут) в 3-4 приёма. Проводят 3 курса по 14-28 дней с интервалом 1 месяц.\u003Cbr\u003EДисплазия шейки матки, ассоциированная с папилломавирусом человека: 2-3 курса по 1000 мг 3 раза в сутки (60 мл/сут) в течение 10 дней с интервалом 10-14 дней.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EПрименение у пожилых пациентов: необходимости в коррекции дозы нет, препарат применяется так же, как у пациентов среднего возраста. Следует учитывать, что у пожилых пациентов чаще происходит повышение концентрации мочевой кислоты в сыворотке крови и в моче, чем у пациентов среднего возраста.\u003Cbr\u003EПациенты с почечной и печеночной недостаточностью: на фоне лечения препаратом Гроприносин-Рихтер следует каждые 2 недели проводить контроль содержания мочевой кислоты в сыворотке крови и моче. Контроль активности печеночных ферментов рекомендуется проводить каждые 4 недели при длительных курсах лечения препаратом."},{"name":"Побочные действия","value":"Частота развития побочных действий после применения препарата классифицирована согласно рекомендациям ВОЗ: частые - \u003E1% и \u003C10%; нечастые - \u003E0,1% и \u003C1%.\u003Cbr\u003EСо стороны нервной системы: частые - головная боль, головокружение, утомляемость, плохое самочувствие, слабость; нечастые - нервозность, сонливость, бессонница.\u003Cbr\u003EСо стороны желудочно-кишечного тракта: частые - снижение аппетита, тошнота, рвота, боль в эпигастрии; нечастые - диарея, запор.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: частые - временное повышение активности трансаминаз и щелочной фосфатазы в плазме крови, повышение концентрации мочевины в плазме крови.\u003Cbr\u003EСо стороны кожи и подкожных тканей: частые - зуд, сыпь; нечастые - макулопапулезная сыпь, крапивница, ангионевротический отек.\u003Cbr\u003EСо стороны почек и мочевыводящих путей: нечастые - полиурия.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: частые - боль в суставах, обострение подагры.\u003Cbr\u003EЛабораторные и инструментальные данные: частые - повышение концентрации азота мочевины крови."},{"name":"Фармакологическое действие","value":"Инозин пранобекс - синтетическое производное пурина, представляет собой комплекс, содержащий инозин и N,N-диметиламино-2-пропанол в молярном соотношении 1:3.\u003Cbr\u003EОбладает иммуностимулирующей активностью и неспецифическим противовирусным действием. Эффективность комплекса определяется присутствием инозина, второй компонент повышает его доступность для лимфоцитов.\u003Cbr\u003EВосстанавливает функции лимфоцитов в условиях иммунодепрессии, повышает бластогенез в популяции моноцитов, стимулирует экспрессию мембранных рецепторов на поверхности Т-хелперов, предупреждает снижение активности лимфоцитов под влиянием глюкокортикостероидов, нормализует включение в них тимидина. Инозин пранобекс стимулирует активность Т-лимфоцитов и естественных киллеров, функции Т-супрессоров и Т-хелперов, повышает продукцию иммуноглобулина G (IgG), интерферона-гамма, интерлейкинов ИЛ-1 и ИЛ-2, снижает образование противовоспалительных цитокинов - ИЛ-4 и ИЛ-10, потенцирует хемотаксис нейтрофилов, моноцитов и макрофагов.\u003Cbr\u003EПрепарат проявляет противовирусную активность in vivo в отношении вируса простого герпеса, цитомегаловируса, вируса кори, вируса Т-клеточной лимфомы человека (тип III), полиовирусов, вирусов гриппа А и В, ЕСНО-вируса (энтероцитопатогенного вируса человека), вирусов энцефаломиокардита и конского энцефалита.\u003Cbr\u003EМеханизм противовирусного действия инозина пранобекса связан с ингибированием вирусной РНК и дигидроптероатсинтетазы, участвующей в репликации некоторых вирусов, усиливает подавленный вирусами синтез мРНК лимфоцитов, что сопровождается уменьшением синтеза вирусной РНК и трансляции вирусных белков, повышает продукцию лимфоцитами обладающих противовирусными свойствами альфа и гамма интерферонов.\u003Cbr\u003EПри комбинированном назначении усиливает действие интерферона-альфа, ацикловира и зидовудина."},{"name":"Фармакологическая группа","value":"иммуностимулирующее средство"},{"name":"Форма выпуска","value":"сироп"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 3 лет"},{"name":"Комплектация","value":"В комплекте со шприцем."},{"name":"Условия хранения","value":"При температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При передозировке показано промывание желудка и симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Гроприносин-Рихтер во время беременности и в период грудного вскармливания противопоказано, так как безопасность применения не установлена."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние инозина пранобекса на психомоторные функции организма и способность управлять транспортными средствами и движущимися механизмами не исследовалось. При применении препарата следует учитывать возможность возникновения головокружения и сонливости."},{"name":"Особые указания","value":"Инозин пранобекс, как и другие противовирусные средства, наиболее эффективен при острых вирусных инфекциях, если лечение начато на ранней стадии болезни (первые сутки). После 2-х недель применения инозин пранобекса следует провести контроль концентрации мочевой кислоты в сыворотке крови и моче. Также при длительном применении рекомендуется периодически контролировать концентрацию мочевой кислоты в сыворотке крови и моче.\u003Cbr\u003EПациенты со значительно повышенной концентрацией мочевой кислоты в организме могут одновременно принимать препараты, понижающие ее концентрацию. Необходимо контролировать концентрацию мочевой кислоты в сыворотке крови при назначении препарата одновременно с препаратами, увеличивающими концентрацию мочевой кислоты или препаратами, нарушающими функцию почек.\u003Cbr\u003EПри длительном приеме (после четырех недель применения) целесообразно каждый месяц проводить контроль функции печени и почек (активность трансаминаз, уровень креатинина, мочевая кислота в сыворотке крови). Инозин пранобекс следует с осторожностью применять пациентам с острой печеночной недостаточностью, поскольку препарат подвергается метаболизму"},{"name":"Взаимодействие","value":"Иммунодепрессанты ослабляют иммуностимулирующий эффект инозина пранобекса.\u003Cbr\u003EИнозин пранобекс следует применять с осторожностью пациентам, принимающим одновременно ингибиторы ксантиноксидазы (аллопуринол) или препараты, способные блокировать канальцевую секрецию мочевой кислоты, например, \"петлевые\" диуретики (фуросемид, торасемид, этакриновая кислота), так как это может приводить к повышению концентрации мочевой кислоты в сыворотке крови.\u003Cbr\u003EСовместное применение инозина пранобекса с зидовудином приводит к увеличению концентрации зидовудина в плазме крови и удлиняет его период полувыведения. Таким образом, при совместном применении инозина пранобекса с зидовудином может потребоваться коррекция дозы зидовудина."},{"name":"Регистрационный номер","value":"ЛП-005233"},{"name":"Дата государственной регистрации","value":"05.12.2018"},{"name":"Владелец регистрационного удостоверения","value":"Гедеон Рихтер ОАО","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["34324371:35649313","7893318:17672958"]}}},{"name":"Изготовитель","value":"Гедеон Рихтер Румыния А.О."},{"name":"Фасовщик","value":"Гедеон Рихтер Румыния А.О."},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Румыния"},{"name":"Название препарата","value":"Гроприносин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-grippa-i-prostudy","categoryId":"15756357","navnodeId":"25024950","glfilters":["17796364:17992145"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"7951246096553716429":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"дыхательная система, кожа"},{"name":"Назначение","value":"ОРВИ, генитальный герпес, герпес, инфекции кожи и слизистых оболочек, вызванные вирусом герпеса, инфекционный мононуклеоз, контагиозный моллюск, корь, лечение гриппа, лечение инфекций, вызванных вирусом простого герпеса (ВПГ), лечение офтальмического опоясывающего герпеса, опоясывающий герпес (лишай), папилломавирусная инфекция, подострый склерозирующий панэнцефалит, укрепление иммунитета, цитомегаловирусная инфекция"},{"name":"Показания к применению","value":"- Грипп и острые респираторные вирусные инфекции.\u003Cbr\u003E- Инфекции, вызванные вирусом простого герпеса 1, 2, 3 и 4 типов: генитальный и лабиальный герпес, герпетический кератит, опоясывающий лишай, ветряная оспа, инфекционный мононуклеоз, вызванный вирусом Эпштейна-Барр.\u003Cbr\u003E- Цитомегаловирусная инфекция.\u003Cbr\u003E- Корь тяжёлого течения.\u003Cbr\u003E- Папилломавирусная инфекция: папилломы гортани и голосовых связок (фиброзного типа), генитальные папилломавирусные инфекции у мужчин и женщин, бородавки.\u003Cbr\u003E- Подострый склерозирующий панэнцефалит.\u003Cbr\u003E- Контагиозный моллюск."},{"name":"Противопоказания","value":"- Повышенная чувствительность к инозину пранобексу и другим компонентам препарата.\u003Cbr\u003E- Подагра.\u003Cbr\u003E- Мочекаменная болезнь.\u003Cbr\u003E- Аритмии.\u003Cbr\u003E- Хроническая почечная недостаточность.\u003Cbr\u003E- Детский возраст до 3 лет (масса тела до 15-20 кг).\u003Cbr\u003E- Беременность и период грудного вскармливания.\u003Cbr\u003E- Дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EСледует соблюдать осторожность при одновременном назначении с ингибиторами ксантиноксидазы, диуретиками, зидовудином, при острой печеночной недостаточности."},{"name":"Состав","value":"1 мл содержит:\u003Cbr\u003EДействующее вещество: Инозин Пранобекс - 50,00 мг.\u003Cbr\u003EВспомогательные вещества: метилпарагидроксибензоат, пропилпарагидроксибензоат, сахароза, натрия гидроксид, лимонная кислота, вода."},{"name":"Действующее вещество","value":"Инозин Пранобекс"},{"name":"Способ применения и дозы","value":"Способ применения\u003Cbr\u003EВнутрь после еды. Для правильного дозирования прилагается мерный шприц для приёма препарата внутрь.\u003Cbr\u003EДозы\u003Cbr\u003EДоза препарата зависит от массы тела пациента и заболевания. Суточную дозу разделяют на несколько частей (3-4), которые следует принимать через равные промежутки времени в течение дня. Продолжительность лечения обычно составляет 5-14 дней. Приём препарата следует продолжить в течение 1-2 дней после исчезновения симптомов.\u003Cbr\u003EРекомендуемая суточная доза для взрослых и пожилых пациентов, а также детей 3 лет и старше (масса тела больше 15-20 кг) составляет 50 мг/кг массы тела в 3-4 приёма. 1 мл препарата Гроприносин-Рихтер содержит 50 мг инозина пранобекса.\u003Cbr\u003EДля лечения тяжёлых инфекций дозу можно индивидуально увеличивать до 100 мг/кг массы тела 4-6 раз в сутки. Максимальная суточная доза для взрослых составляет 3-4 г/сут (60-80 мл/сут).\u003Cbr\u003EМаксимальная суточная доза для детей от 3 лет и старше - 50 мг/кг/сут.\u003Cbr\u003EПродолжительность лечения\u003Cbr\u003EОстрые инфекции: продолжительность лечения у взрослых и детей обычно от 5 до 14 дней. Лечение следует продолжать до момента исчезновения клинических симптомов и в течение ещё 1-2 дней после исчезновения симптомов. При необходимости длительность лечения может быть увеличена индивидуально под контролем врача.\u003Cbr\u003EХронические рецидивирующие инфекции: у взрослых и детей лечение необходимо продолжать несколькими курсами по 5-10 дней с интервалом 8 дней. При проведении поддерживающей терапии доза может быть снижена до 500-1000 мг в сутки (10-20 мл/сут) в течение 30 дней.\u003Cbr\u003EГерпетические инфекции: лечение продолжается в течение 5-10 дней до исчезновения симптомов заболевания. Для уменьшения числа рецидивов в бессимптомный период препарат назначают по 500 мг 2 раза в сутки (20 мл/сут) в течение 30 дней.\u003Cbr\u003EПапилломавирусные инфекции: в качестве монотерапии препарат назначается на протяжении 14-28 дней взрослым в дозе 1000 мг 3 раза в сутки (60 мл/сут), детям - 250 мг на 5 кг массы тела (1 мл/кг/сут) 3-4 раза в сутки.\u003Cbr\u003EРецидивирующие остроконечные кондиломы: в качестве монотерапии или в комбинации с хирургическим лечением препарат назначается взрослым в дозе 1000 мг 3 раза в сутки (60 мл/сут), детям - в дозе 250 мг на 5 кг массы тела (1 мл/кг/сут) в 3-4 приёма. Проводят 3 курса по 14-28 дней с интервалом 1 месяц.\u003Cbr\u003EДисплазия шейки матки, ассоциированная с папилломавирусом человека: 2-3 курса по 1000 мг 3 раза в сутки (60 мл/сут) в течение 10 дней с интервалом 10-14 дней.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EПрименение у пожилых пациентов: необходимости в коррекции дозы нет, препарат применяется так же, как у пациентов среднего возраста. Следует учитывать, что у пожилых пациентов чаще происходит повышение концентрации мочевой кислоты в сыворотке крови и в моче, чем у пациентов среднего возраста.\u003Cbr\u003EПациенты с почечной и печеночной недостаточностью: на фоне лечения препаратом Гроприносин-Рихтер следует каждые 2 недели проводить контроль содержания мочевой кислоты в сыворотке крови и моче. Контроль активности печеночных ферментов рекомендуется проводить каждые 4 недели при длительных курсах лечения препаратом."},{"name":"Побочные действия","value":"Частота развития побочных действий после применения препарата классифицирована согласно рекомендациям ВОЗ: частые - \u003E1% и \u003C10%; нечастые - \u003E0,1% и \u003C1%.\u003Cbr\u003EСо стороны нервной системы: частые - головная боль, головокружение, утомляемость, плохое самочувствие, слабость; нечастые - нервозность, сонливость, бессонница.\u003Cbr\u003EСо стороны желудочно-кишечного тракта: частые - снижение аппетита, тошнота, рвота, боль в эпигастрии; нечастые - диарея, запор.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: частые - временное повышение активности трансаминаз и щелочной фосфатазы в плазме крови, повышение концентрации мочевины в плазме крови.\u003Cbr\u003EСо стороны кожи и подкожных тканей: частые - зуд, сыпь; нечастые - макулопапулезная сыпь, крапивница, ангионевротический отек.\u003Cbr\u003EСо стороны почек и мочевыводящих путей: нечастые - полиурия.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: частые - боль в суставах, обострение подагры.\u003Cbr\u003EЛабораторные и инструментальные данные: частые - повышение концентрации азота мочевины крови."},{"name":"Фармакологическое действие","value":"Инозин пранобекс - синтетическое производное пурина, представляет собой комплекс, содержащий инозин и N,N-диметиламино-2-пропанол в молярном соотношении 1:3.\u003Cbr\u003EОбладает иммуностимулирующей активностью и неспецифическим противовирусным действием. Эффективность комплекса определяется присутствием инозина, второй компонент повышает его доступность для лимфоцитов.\u003Cbr\u003EВосстанавливает функции лимфоцитов в условиях иммунодепрессии, повышает бластогенез в популяции моноцитов, стимулирует экспрессию мембранных рецепторов на поверхности Т-хелперов, предупреждает снижение активности лимфоцитов под влиянием глюкокортикостероидов, нормализует включение в них тимидина. Инозин пранобекс стимулирует активность Т-лимфоцитов и естественных киллеров, функции Т-супрессоров и Т-хелперов, повышает продукцию иммуноглобулина G (IgG), интерферона-гамма, интерлейкинов ИЛ-1 и ИЛ-2, снижает образование противовоспалительных цитокинов - ИЛ-4 и ИЛ-10, потенцирует хемотаксис нейтрофилов, моноцитов и макрофагов.\u003Cbr\u003EПрепарат проявляет противовирусную активность in vivo в отношении вируса простого герпеса, цитомегаловируса, вируса кори, вируса Т-клеточной лимфомы человека (тип III), полиовирусов, вирусов гриппа А и В, ЕСНО-вируса (энтероцитопатогенного вируса человека), вирусов энцефаломиокардита и конского энцефалита.\u003Cbr\u003EМеханизм противовирусного действия инозина пранобекса связан с ингибированием вирусной РНК и дигидроптероатсинтетазы, участвующей в репликации некоторых вирусов, усиливает подавленный вирусами синтез мРНК лимфоцитов, что сопровождается уменьшением синтеза вирусной РНК и трансляции вирусных белков, повышает продукцию лимфоцитами обладающих противовирусными свойствами альфа и гамма интерферонов.\u003Cbr\u003EПри комбинированном назначении усиливает действие интерферона-альфа, ацикловира и зидовудина."},{"name":"Фармакологическая группа","value":"иммуностимулирующее средство"},{"name":"Форма выпуска","value":"сироп"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 3 лет"},{"name":"Комплектация","value":"В комплекте со шприцем."}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При передозировке показано промывание желудка и симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Гроприносин-Рихтер во время беременности и в период грудного вскармливания противопоказано, так как безопасность применения не установлена."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние инозина пранобекса на психомоторные функции организма и способность управлять транспортными средствами и движущимися механизмами не исследовалось. При применении препарата следует учитывать возможность возникновения головокружения и сонливости."},{"name":"Особые указания","value":"Инозин пранобекс, как и другие противовирусные средства, наиболее эффективен при острых вирусных инфекциях, если лечение начато на ранней стадии болезни (первые сутки). После 2-х недель применения инозин пранобекса следует провести контроль концентрации мочевой кислоты в сыворотке крови и моче. Также при длительном применении рекомендуется периодически контролировать концентрацию мочевой кислоты в сыворотке крови и моче.\u003Cbr\u003EПациенты со значительно повышенной концентрацией мочевой кислоты в организме могут одновременно принимать препараты, понижающие ее концентрацию. Необходимо контролировать концентрацию мочевой кислоты в сыворотке крови при назначении препарата одновременно с препаратами, увеличивающими концентрацию мочевой кислоты или препаратами, нарушающими функцию почек.\u003Cbr\u003EПри длительном приеме (после четырех недель применения) целесообразно каждый месяц проводить контроль функции печени и почек (активность трансаминаз, уровень креатинина, мочевая кислота в сыворотке крови). Инозин пранобекс следует с осторожностью применять пациентам с острой печеночной недостаточностью, поскольку препарат подвергается метаболизму"},{"name":"Взаимодействие","value":"Иммунодепрессанты ослабляют иммуностимулирующий эффект инозина пранобекса.\u003Cbr\u003EИнозин пранобекс следует применять с осторожностью пациентам, принимающим одновременно ингибиторы ксантиноксидазы (аллопуринол) или препараты, способные блокировать канальцевую секрецию мочевой кислоты, например, \"петлевые\" диуретики (фуросемид, торасемид, этакриновая кислота), так как это может приводить к повышению концентрации мочевой кислоты в сыворотке крови.\u003Cbr\u003EСовместное применение инозина пранобекса с зидовудином приводит к увеличению концентрации зидовудина в плазме крови и удлиняет его период полувыведения. Таким образом, при совместном применении инозина пранобекса с зидовудином может потребоваться коррекция дозы зидовудина."},{"name":"Регистрационный номер","value":"ЛП-005233"},{"name":"Дата государственной регистрации","value":"05.12.2018"},{"name":"Владелец регистрационного удостоверения","value":"Гедеон Рихтер ОАО"},{"name":"Изготовитель","value":"Гедеон Рихтер Румыния А.О."},{"name":"Фасовщик","value":"Гедеон Рихтер Румыния А.О."},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Румыния"},{"name":"Название препарата","value":"Гроприносин"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_8195478131585535848"}}}}
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Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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720 ₽

  • Сегодня, самовывоз • 0 ₽
ЕАПТЕКА
Рейтинг 5 из 5
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    Ранкоф Тимошка сироп от кашля д/детей фл., 100 мл, 100 г, 1 шт., нейтральный, нейтральный, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 229 оценок
    Цена 319 ₽ вместо 431
    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  • Нормомед сироп фл. (в компл. с мерным колпачком), 50 мг/мл, 120 мл
    –1 %
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    Нормомед сироп фл. (в компл. с мерным колпачком), 50 мг/мл, 120 мл

    Рейтинг товара: 4.9 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 898 ₽ вместо 907
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  • Ингавирин сироп фл., 30 мг/5 мл, 90 мл
    –1 %
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    Ингавирин сироп фл., 30 мг/5 мл, 90 мл

    Рейтинг товара: 5 из 5
    на основе 7 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 744 ₽ вместо 752
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  • Грипмакс Нос Детский таб. жев., 15 шт., банан
    –8 %
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    Грипмакс Нос Детский таб. жев., 15 шт., банан

    Рейтинг товара: 4.9 из 5
    на основе 43 оценки
    Цена 442 ₽ вместо 480
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  • Цитовир-3 пор. д/приг. р-ра д/вн. приема д/детей фл. с доз. устр-вом, 20 г, апельсин
    –1 %
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    Цитовир-3 пор. д/приг. р-ра д/вн. приема д/детей фл. с доз. устр-вом, 20 г, апельсин

    Рейтинг товара: 5 из 5
    на основе 40 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 474 ₽ вместо 479
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  • Арбидол пор. д/приг. сусп. д/вн. приема фл., 25 мг/5 мл, 37 г
    –1 %
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    Арбидол пор. д/приг. сусп. д/вн. приема фл., 25 мг/5 мл, 37 г

    Рейтинг товара: 4.3 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 430 ₽ вместо 434
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  • Римантадин Кидс сироп фл., 2 мг/мл, 200 мл
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    Римантадин Кидс сироп фл., 2 мг/мл, 200 мл

    Рейтинг товара: 5 из 5
    на основе 7 оценок
    Цена 405 ₽
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  • Орвирем сироп д/детей фл., 2 мг/мл, 100 мл
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    Орвирем сироп д/детей фл., 2 мг/мл, 100 мл

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 442 ₽
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  • Гроприносин таб., 500 мг, 20 шт.
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    Гроприносин таб., 500 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 23 оценки
    Цена 780 ₽
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  • Реглисам д/детей гран. д/приг. сусп. д/вн. приема пак., 25 мг, 1.3 г, 30 шт.
    –1 %
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    Реглисам д/детей гран. д/приг. сусп. д/вн. приема пак., 25 мг, 1.3 г, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 49 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 627 ₽ вместо 633
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  • Анаферон детский таб. д/рассас., 20 шт.
    –1 %
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    Анаферон детский таб. д/рассас., 20 шт.

    Рейтинг товара: 4.7 из 5
    на основе 14 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 341 ₽ вместо 344
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  • Цитовир-3 капс., 12 шт.
    –1 %
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    Цитовир-3 капс., 12 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 550 ₽ вместо 556
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Инструкция

Показания к применению

- Грипп и острые респираторные вирусные инфекции.
- Инфекции, вызванные вирусом простого герпеса 1, 2, 3 и 4 типов: генитальный и лабиальный герпес, герпетический кератит, опоясывающий лишай, ветряная оспа, инфекционный мононуклеоз, вызванный вирусом Эпштейна-Барр.
- Цитомегаловирусная инфекция.
- Корь тяжёлого течения.
- Папилломавирусная инфекция: папилломы гортани и голосовых связок (фиброзного типа), генитальные папилломавирусные инфекции у мужчин и женщин, бородавки.
- Подострый склерозирующий панэнцефалит.
- Контагиозный моллюск.

Противопоказания

- Повышенная чувствительность к инозину пранобексу и другим компонентам препарата.
- Подагра.
- Мочекаменная болезнь.
- Аритмии.
- Хроническая почечная недостаточность.
- Детский возраст до 3 лет (масса тела до 15-20 кг).
- Беременность и период грудного вскармливания.
- Дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция.
С осторожностью:
Следует соблюдать осторожность при одновременном назначении с ингибиторами ксантиноксидазы, диуретиками, зидовудином, при острой печеночной недостаточности.

Способ применения и дозы

Способ применения
Внутрь после еды. Для правильного дозирования прилагается мерный шприц для приёма препарата внутрь.
Дозы
Доза препарата зависит от массы тела пациента и заболевания. Суточную дозу разделяют на несколько частей (3-4), которые следует принимать через равные промежутки времени в течение дня. Продолжительность лечения обычно составляет 5-14 дней. Приём препарата следует продолжить в течение 1-2 дней после исчезновения симптомов.
Рекомендуемая суточная доза для взрослых и пожилых пациентов, а также детей 3 лет и старше (масса тела больше 15-20 кг) составляет 50 мг/кг массы тела в 3-4 приёма. 1 мл препарата Гроприносин-Рихтер содержит 50 мг инозина пранобекса.
Для лечения тяжёлых инфекций дозу можно индивидуально увеличивать до 100 мг/кг массы тела 4-6 раз в сутки. Максимальная суточная доза для взрослых составляет 3-4 г/сут (60-80 мл/сут).
Максимальная суточная доза для детей от 3 лет и старше - 50 мг/кг/сут.
Продолжительность лечения
Острые инфекции: продолжительность лечения у взрослых и детей обычно от 5 до 14 дней. Лечение следует продолжать до момента исчезновения клинических симптомов и в течение ещё 1-2 дней после исчезновения симптомов. При необходимости длительность лечения может быть увеличена индивидуально под контролем врача.
Хронические рецидивирующие инфекции: у взрослых и детей лечение необходимо продолжать несколькими курсами по 5-10 дней с интервалом 8 дней. При проведении поддерживающей терапии доза может быть снижена до 500-1000 мг в сутки (10-20 мл/сут) в течение 30 дней.
Герпетические инфекции: лечение продолжается в течение 5-10 дней до исчезновения симптомов заболевания. Для уменьшения числа рецидивов в бессимптомный период препарат назначают по 500 мг 2 раза в сутки (20 мл/сут) в течение 30 дней.
Папилломавирусные инфекции: в качестве монотерапии препарат назначается на протяжении 14-28 дней взрослым в дозе 1000 мг 3 раза в сутки (60 мл/сут), детям - 250 мг на 5 кг массы тела (1 мл/кг/сут) 3-4 раза в сутки.
Рецидивирующие остроконечные кондиломы: в качестве монотерапии или в комбинации с хирургическим лечением препарат назначается взрослым в дозе 1000 мг 3 раза в сутки (60 мл/сут), детям - в дозе 250 мг на 5 кг массы тела (1 мл/кг/сут) в 3-4 приёма. Проводят 3 курса по 14-28 дней с интервалом 1 месяц.
Дисплазия шейки матки, ассоциированная с папилломавирусом человека: 2-3 курса по 1000 мг 3 раза в сутки (60 мл/сут) в течение 10 дней с интервалом 10-14 дней.
Особые группы пациентов
Применение у пожилых пациентов: необходимости в коррекции дозы нет, препарат применяется так же, как у пациентов среднего возраста. Следует учитывать, что у пожилых пациентов чаще происходит повышение концентрации мочевой кислоты в сыворотке крови и в моче, чем у пациентов среднего возраста.
Пациенты с почечной и печеночной недостаточностью: на фоне лечения препаратом Гроприносин-Рихтер следует каждые 2 недели проводить контроль содержания мочевой кислоты в сыворотке крови и моче. Контроль активности печеночных ферментов рекомендуется проводить каждые 4 недели при длительных курсах лечения препаратом.
Полная инструкция
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Гроприносин-Рихтер сироп фл.
Гроприносин-Рихтер сироп фл., 50 мг/мл, 150 мл
5.0
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1 вопрос
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720 ₽

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