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Описание

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Глюконорм таб. п/о плен., 2.5 мг+400 мг, 40 шт.

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Коротко о товаре

Артикул Маркета
3420512863
Тип препарата
Назначение
Действующее вещество
Форма выпуска
таблетки
Инструкция
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типа","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["36476390:36618138"]}}},{"name":"Показания к применению","value":"Сахарный диабет 2 типа у взрослых:\u003Cbr\u003E-при неэффективности диетотерапии, физических упражнений и предшествующей терапии метформином или глибенкламидом;\u003Cbr\u003E-для замещения предшествующей терапии двумя препаратами (метформином и глибенкламидом) у больных со стабильным и хорошо контролируемым уровнем глюкозы крови."},{"name":"Противопоказания","value":"- Повышенная чувствительность к метформину, глибенкламиду или другим производным сульфонилмочевины, а также к вспомогательным веществам;\u003Cbr\u003E- сахарный диабет 1 типа;\u003Cbr\u003E- диабет ический кетоацидоз, диабетическая прекома, диабетическая кома;\u003Cbr\u003E- гипогликемия:\u003Cbr\u003E- тяжелые нарушения функции почек;\u003Cbr\u003E- острые состояния, которые могут приводить к изменению функции почек: дегидратация, тяжелая инфекция, шок;\u003Cbr\u003E- острые или хронические заболевания, сопровождающиеся гипоксией тканей: сердечная или дыхательная недостаточность, недавний инфаркт миокарда, шок;\u003Cbr\u003E- печеночная недостаточность;\u003Cbr\u003E- порфирия;\u003Cbr\u003E- беременность, период грудного вскармливания;\u003Cbr\u003E- одновременный прием миконазола;\u003Cbr\u003E- инфекционные заболевания, большие хирургические вмешательства, травмы, обширные ожоги и другие состояния, требующие проведения инсулинотерапии;\u003Cbr\u003E- хронический алкоголизм, острая алкогольная интоксикация:\u003Cbr\u003E- лактоацидоз (в т.ч. в анамнезе);\u003Cbr\u003E- применение в течение не менее 48 часов до и в течение 48 часов после проведения радиоизотопных или рентгенологических исследований с введением йодсодержащего контрастного вещества;\u003Cbr\u003E- соблюдение гипокалорийной диеты (менее 1000 кал/сут).\u003Cbr\u003EНе рекомендуется применять препарат у лиц старше 60 лет, выполняющих тяжелую физическую работу, что связано с повышенным риском развития у них лактоацидоза.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EЛихорадочный синдром, надпочечниковая недостаточность, гипофункция передней доли гипофиза, заболевания щитовидной железы с нарушением ее функции."},{"name":"Состав","value":"Каждая таблетка, покрытая пленочной оболочкой, содержит:\nактивные вещества: метформина гидрохлорид - 400 мг, глибенкламид - 2,5 мг;\u003Cbr\u003Eвспомогательные вещества: целлюлоза микрокристаллическая 100,0 мг, крахмал кукурузный - 20,0 мг, кремния диоксид коллоидный - 20,0 мг, желатин - 10,0 мг, глицерол - 10,0 мг, магния стеарат - 7,0 мг, тальк - 15,0 мг, кроскармеллоза натрия - 30,0 мг, карбоксиметилкрахмал натрия - 18,3 мг, целлацефат - 2,0 мг, диэтилфталат - 0,2 мг."},{"name":"Действующее вещество","value":"Глибенкламид+Метформин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["27144131:36089434"]}}},{"name":"Способ применения и дозы","value":"Препарат применяют внутрь, во время еды. Доза препарата определяется врачом индивидуально для каждого пациента в зависимости от концентрации глюкозы в крови. Обычно начальная доза составляет 1 таблетку в день. Каждые 1-2 недели после начала лечения дозу препарата корректируют в зависимости от концентрации глюкозы в крови. При замещении предшествующей комбинированной терапии метформином и глибекламидом назначают 1-2 таблетки препарата Глюконорм, в зависимости от предыдущей дозы каждого компонента. Максимальная суточная доза составляет 5 таблеток."},{"name":"Побочные действия","value":"Со стороны углеводного обмена: возможна гипогликемия.\u003Cbr\u003EСо стороны ЖКТ и печени: редко - тошнота, рвота, боли в животе, потеря аппетита, \"металлический\" привкус во рту; в отдельных случаях - холестатическая желтуха, повышение активности \"печеночных\" ферментов, гепатит.\u003Cbr\u003EСо стороны системы кроветворения: редко - лейкопения, тромбоцитопения, эритроцитопения: очень редко - агранулоцитоз, гемолитическая или межобластная анемия, панцитопения.\u003Cbr\u003EСо стороны центральной нервной системы: головная боль, головокружение, слабость, повышенная утомляемость, редко - парезы, нарушения чувствительности.\u003Cbr\u003EАллергические и иммунопатологические реакции: редко - крапивница, эритема, кожный зуд. повышение температуры тела, артралгия, протеинурия.\u003Cbr\u003EДерматологические реакции: редко - фотосенсибилизация.\u003Cbr\u003EСо стороны обмена веществ: лактоацидоз.\u003Cbr\u003EПрочие: острая реакция непереносимости алкоголя после его употребления, выражающаяся осложнениями со стороны органов кровообращения и дыхания (дисульфирамоподобная реакция; рвота, ощущение жара в лице и верхней части туловища, тахикардия, головокружение. головная боль)."},{"name":"Фармакологическое действие","value":"Глюконорм представляет собой фиксированную комбинацию двух пероральных гипогликемических средств различных фармакологических групп: метформина и глибенкламида.\u003Cbr\u003EМетформин относится к группе бигуанидов и снижает концентрацию глюкозы в сыворотке крови за счет повышения чувствительности периферических тканей к действию инсулина и усиления захвата глюкозы.\u003Cbr\u003EСнижает всасывание углеводов в желудочно-кишечном тракте и тормозит глюконеогенез в печени. Препарат также оказывает благоприятное действие на липидный профиль крови, снижая концентрацию общего холестерина, ЛПНП и триглицеридов. Не вызывает гипогликемических реакций. Глибенкламид относится к группе производных сульфонилмочевины II поколения. Стимулирует секрецию инсулина путем снижения порога раздражения глюкозой бета-клеток поджелудочной железы, повышает чувствительность к инсулину и степень его связывания с клетками-мишенями, увеличивает высвобождение инсулина, усиливает влияние инсулина на поглощение глюкозы мышцами и печенью, тормозит липолиз в жировой ткани. Действует на вторую фазу секреции инсулина."},{"name":"Фармакологическая группа","value":"гипогликемическое средство для перорального применения комбинированное (бигуанид+производное сульфонилмочевины)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["35947170:36763744"]}}},{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Передозировка или наличие факторов риска могут спровоцировать развитие лактоацидоза, гак как в состав препарата входит метформин. При появлении симптомов лактоацидоза (рвота, боли в животе, общая слабость, мышечные судороги) необходимо прекратить прием препарата. Лактоацидоз является состоянием, требующим неотложной медицинской помощи; лечение лактоацидоза должно проводиться в стационаре. Наиболее эффективным методом лечения является гемодиализ.\u003Cbr\u003EПередозировка также может привести к развитию гипогликемии из-за присутствия в составе препарата глибенкламида. Симптомы гипогликемии: чувство голода, повышенная потливость, слабость, сердцебиение, бледность кожных покровов, парестезия слизистой оболочки полости рта, тремор, общее беспокойство, головная боль, патологическая сонливость. расстройства сна, чувство страха, нарушение координации движений, временные неврологические расстройства. При прогрессировании гипогликемии возможна потеря больным самоконтроля и сознания.\u003Cbr\u003EПри гипогликемии легкой или средней тяжести декстрозу (глюкозу) или раствор сахара принимают внутрь, В случае тяжелой гипогликемии (потеря сознания) вводят внутривенно 40 % раствор декстрозы (глюкозы) или глюкагон внутривенно, внутримышечно, подкожно. После восстановления сознания больному необходимо дать пищу, богатую углеводами. во избежание повторного развития гипогликемии."},{"name":"Применение при беременности и кормлении грудью","value":"В период беременности применение препарата Глюконорм противопоказано. При планировании беременности, а также в случае наступления беременности в период приема препарата Глюконорм®, препарат должен быть отменен и назначена инсулинотерапия.\u003Cbr\u003EГлюконорм противопоказан при грудном вскармливании, поскольку метформин проникает в грудное молоко. В этом случае необходимо перейти на инсулинотерапию или прекратить кормление грудью."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения необходимо соблюдать осторожность при управлении транспортными средствами и механизмами и при занятиях другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Большие хирургические вмешательства и травмы, обширные ожоги, инфекционные заболевания с лихорадочным синдромом могут потребовать отмены препарата и назначения инсулинотерапии.\u003Cbr\u003EНеобходимо регулярно контролировать содержание глюкозы в крови натощак и после приема пищи.\u003Cbr\u003EСледует предупредить пациентов о повышенном риске возникновения гипогликемии в случаях приема этанола, НПВП, при голодании.\u003Cbr\u003EНеобходима коррекция дозы при физическом и эмоциональном перенапряжении, изменении режима питания. Во время лечения не рекомендуется принимать алкоголь. За 48 часов до хирургического вмешательства или внутривенного введения йодсодержащего рентгеноконтрастного средства прием препарата Глюконорм следует прекратить. Лечение препаратом Глюконорм рекомендуется возобновить через 48 часов."},{"name":"Взаимодействие","value":"Взаимодействие с другими лекарственными средствами\u003Cbr\u003EУсиливают гипогликемическое действие препарата ингибиторы ангиотензин- превращающего фермента (каптоприл, эналаприл), блокаторы Н2-гистаминовых рецепторов (циметидин), противогрибковые лекарственные средства (миконазол, флуконазол), нестероидные противовоспалительные препараты (НПВП) (фенилбутазон, азапропазон, оксифенбутазон), фибраты (клофибрат, безафибрат), противотуберкулезные (этионамид), салицилаты, антикоагулянты кумаринового ряда, анаболические стероиды, бета-адреноблокаторы, ингибиторы моноаминооксидазы, сульфаниламиды длительного действия, циклофосфамид, хлорамфеникол, фенфлурамин, флуоксетин, гуанетидин, пентоксифиллин, тетрациклин, теофиллин, блокаторы канальциевой секреции, резерпин, бромокриптин, дизопирамид, пиридоксин, другие гипогликемические препараты (акарбоза, бигуаниды, инсулин и др.), аллопуринол.\u003Cbr\u003EОслабляют эффект барбитураты, глюкокортикостероиды, адреностимуляторы (эпинефрин, клонидин), противоэпилептические препараты (фенитоин), блокаторы \"медленных\" кальциевых каналов, ингибиторы карбоангидразы (ацетазоламид), тиазидные диуретики, хлорталидон, фуросемид, триамтерен, аспарагиназа, баклофен, даназол, диазоксид, изониазид, морфин, ритодрин, сальбутамол, тербуталин, глюкагон, рифампицин, йодсодержащие гормоны щитовидной железы, соли лития, в высоких дозах - никотиновая кислота, хлорпромазин, пероральные контрацептивы и эстрогены.\u003Cbr\u003EПодкисляющие мочу лекарственные средства (аммония хлорид, кальция хлорид, аскорбиновая кислота в больших дозах) усиливают действие за счет уменьшения степени диссоциации и повышения реабсорбции глибенкламида.\u003Cbr\u003EЭтанол усиливает вероятность развития лактоацидоза.\u003Cbr\u003EМетформин уменьшает максимальную концентрацию в крови (Сmах) и Т1/2 фуросемида на 31 и 42,3 % соответственно.\u003Cbr\u003EФуросемид увеличивает Сmах метформина на 22 %.\u003Cbr\u003EНифедипин повышает абсорбцию, Сmах, замедляет выведение метформина.\u003Cbr\u003EКатионные лекарственные средства (амилорид, дигоксин, морфин, прокаинамид, хинидин, хинин, ранитидин, триамтерен и ванкомицин), секретирующиеся в канальцах, конкурируют за канальциевые транспортные системы и при длительной терапии могут увеличить Сmах метформина на 60 %."},{"name":"Регистрационный номер","value":"ЛCP-009610/09"},{"name":"Дата государственной регистрации","value":"10.06.2010"},{"name":"Владелец регистрационного удостоверения","value":"M.J.Biopharm","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["34324371:35649313","7893318:16077127"]}}},{"name":"Изготовитель","value":"M.J.Biopharm"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Глюконорм","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-sakharnogo-diabeta","categoryId":"15756510","navnodeId":"72472","glfilters":["17796364:18046644"]}}},{"name":"Срок годности","value":"35 мес."}]}},"fullSpecsGrouped":{"17993221696313214539":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"эндокринная система"},{"name":"Назначение","value":"сахарный диабет 2 типа"},{"name":"Показания к применению","value":"Сахарный диабет 2 типа у взрослых:\u003Cbr\u003E-при неэффективности диетотерапии, физических упражнений и предшествующей терапии метформином или глибенкламидом;\u003Cbr\u003E-для замещения предшествующей терапии двумя препаратами (метформином и глибенкламидом) у больных со стабильным и хорошо контролируемым уровнем глюкозы крови."},{"name":"Противопоказания","value":"- Повышенная чувствительность к метформину, глибенкламиду или другим производным сульфонилмочевины, а также к вспомогательным веществам;\u003Cbr\u003E- сахарный диабет 1 типа;\u003Cbr\u003E- диабет ический кетоацидоз, диабетическая прекома, диабетическая кома;\u003Cbr\u003E- гипогликемия:\u003Cbr\u003E- тяжелые нарушения функции почек;\u003Cbr\u003E- острые состояния, которые могут приводить к изменению функции почек: дегидратация, тяжелая инфекция, шок;\u003Cbr\u003E- острые или хронические заболевания, сопровождающиеся гипоксией тканей: сердечная или дыхательная недостаточность, недавний инфаркт миокарда, шок;\u003Cbr\u003E- печеночная недостаточность;\u003Cbr\u003E- порфирия;\u003Cbr\u003E- беременность, период грудного вскармливания;\u003Cbr\u003E- одновременный прием миконазола;\u003Cbr\u003E- инфекционные заболевания, большие хирургические вмешательства, травмы, обширные ожоги и другие состояния, требующие проведения инсулинотерапии;\u003Cbr\u003E- хронический алкоголизм, острая алкогольная интоксикация:\u003Cbr\u003E- лактоацидоз (в т.ч. в анамнезе);\u003Cbr\u003E- применение в течение не менее 48 часов до и в течение 48 часов после проведения радиоизотопных или рентгенологических исследований с введением йодсодержащего контрастного вещества;\u003Cbr\u003E- соблюдение гипокалорийной диеты (менее 1000 кал/сут).\u003Cbr\u003EНе рекомендуется применять препарат у лиц старше 60 лет, выполняющих тяжелую физическую работу, что связано с повышенным риском развития у них лактоацидоза.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EЛихорадочный синдром, надпочечниковая недостаточность, гипофункция передней доли гипофиза, заболевания щитовидной железы с нарушением ее функции."},{"name":"Состав","value":"Каждая таблетка, покрытая пленочной оболочкой, содержит:\nактивные вещества: метформина гидрохлорид - 400 мг, глибенкламид - 2,5 мг;\u003Cbr\u003Eвспомогательные вещества: целлюлоза микрокристаллическая 100,0 мг, крахмал кукурузный - 20,0 мг, кремния диоксид коллоидный - 20,0 мг, желатин - 10,0 мг, глицерол - 10,0 мг, магния стеарат - 7,0 мг, тальк - 15,0 мг, кроскармеллоза натрия - 30,0 мг, карбоксиметилкрахмал натрия - 18,3 мг, целлацефат - 2,0 мг, диэтилфталат - 0,2 мг."},{"name":"Действующее вещество","value":"Глибенкламид+Метформин"},{"name":"Способ применения и дозы","value":"Препарат применяют внутрь, во время еды. Доза препарата определяется врачом индивидуально для каждого пациента в зависимости от концентрации глюкозы в крови. Обычно начальная доза составляет 1 таблетку в день. Каждые 1-2 недели после начала лечения дозу препарата корректируют в зависимости от концентрации глюкозы в крови. При замещении предшествующей комбинированной терапии метформином и глибекламидом назначают 1-2 таблетки препарата Глюконорм, в зависимости от предыдущей дозы каждого компонента. Максимальная суточная доза составляет 5 таблеток."},{"name":"Побочные действия","value":"Со стороны углеводного обмена: возможна гипогликемия.\u003Cbr\u003EСо стороны ЖКТ и печени: редко - тошнота, рвота, боли в животе, потеря аппетита, \"металлический\" привкус во рту; в отдельных случаях - холестатическая желтуха, повышение активности \"печеночных\" ферментов, гепатит.\u003Cbr\u003EСо стороны системы кроветворения: редко - лейкопения, тромбоцитопения, эритроцитопения: очень редко - агранулоцитоз, гемолитическая или межобластная анемия, панцитопения.\u003Cbr\u003EСо стороны центральной нервной системы: головная боль, головокружение, слабость, повышенная утомляемость, редко - парезы, нарушения чувствительности.\u003Cbr\u003EАллергические и иммунопатологические реакции: редко - крапивница, эритема, кожный зуд. повышение температуры тела, артралгия, протеинурия.\u003Cbr\u003EДерматологические реакции: редко - фотосенсибилизация.\u003Cbr\u003EСо стороны обмена веществ: лактоацидоз.\u003Cbr\u003EПрочие: острая реакция непереносимости алкоголя после его употребления, выражающаяся осложнениями со стороны органов кровообращения и дыхания (дисульфирамоподобная реакция; рвота, ощущение жара в лице и верхней части туловища, тахикардия, головокружение. головная боль)."},{"name":"Фармакологическое действие","value":"Глюконорм представляет собой фиксированную комбинацию двух пероральных гипогликемических средств различных фармакологических групп: метформина и глибенкламида.\u003Cbr\u003EМетформин относится к группе бигуанидов и снижает концентрацию глюкозы в сыворотке крови за счет повышения чувствительности периферических тканей к действию инсулина и усиления захвата глюкозы.\u003Cbr\u003EСнижает всасывание углеводов в желудочно-кишечном тракте и тормозит глюконеогенез в печени. Препарат также оказывает благоприятное действие на липидный профиль крови, снижая концентрацию общего холестерина, ЛПНП и триглицеридов. Не вызывает гипогликемических реакций. Глибенкламид относится к группе производных сульфонилмочевины II поколения. Стимулирует секрецию инсулина путем снижения порога раздражения глюкозой бета-клеток поджелудочной железы, повышает чувствительность к инсулину и степень его связывания с клетками-мишенями, увеличивает высвобождение инсулина, усиливает влияние инсулина на поглощение глюкозы мышцами и печенью, тормозит липолиз в жировой ткани. Действует на вторую фазу секреции инсулина."},{"name":"Фармакологическая группа","value":"гипогликемическое средство для перорального применения комбинированное (бигуанид+производное сульфонилмочевины)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Передозировка или наличие факторов риска могут спровоцировать развитие лактоацидоза, гак как в состав препарата входит метформин. При появлении симптомов лактоацидоза (рвота, боли в животе, общая слабость, мышечные судороги) необходимо прекратить прием препарата. Лактоацидоз является состоянием, требующим неотложной медицинской помощи; лечение лактоацидоза должно проводиться в стационаре. Наиболее эффективным методом лечения является гемодиализ.\u003Cbr\u003EПередозировка также может привести к развитию гипогликемии из-за присутствия в составе препарата глибенкламида. Симптомы гипогликемии: чувство голода, повышенная потливость, слабость, сердцебиение, бледность кожных покровов, парестезия слизистой оболочки полости рта, тремор, общее беспокойство, головная боль, патологическая сонливость. расстройства сна, чувство страха, нарушение координации движений, временные неврологические расстройства. При прогрессировании гипогликемии возможна потеря больным самоконтроля и сознания.\u003Cbr\u003EПри гипогликемии легкой или средней тяжести декстрозу (глюкозу) или раствор сахара принимают внутрь, В случае тяжелой гипогликемии (потеря сознания) вводят внутривенно 40 % раствор декстрозы (глюкозы) или глюкагон внутривенно, внутримышечно, подкожно. После восстановления сознания больному необходимо дать пищу, богатую углеводами. во избежание повторного развития гипогликемии."},{"name":"Применение при беременности и кормлении грудью","value":"В период беременности применение препарата Глюконорм противопоказано. При планировании беременности, а также в случае наступления беременности в период приема препарата Глюконорм®, препарат должен быть отменен и назначена инсулинотерапия.\u003Cbr\u003EГлюконорм противопоказан при грудном вскармливании, поскольку метформин проникает в грудное молоко. В этом случае необходимо перейти на инсулинотерапию или прекратить кормление грудью."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения необходимо соблюдать осторожность при управлении транспортными средствами и механизмами и при занятиях другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Большие хирургические вмешательства и травмы, обширные ожоги, инфекционные заболевания с лихорадочным синдромом могут потребовать отмены препарата и назначения инсулинотерапии.\u003Cbr\u003EНеобходимо регулярно контролировать содержание глюкозы в крови натощак и после приема пищи.\u003Cbr\u003EСледует предупредить пациентов о повышенном риске возникновения гипогликемии в случаях приема этанола, НПВП, при голодании.\u003Cbr\u003EНеобходима коррекция дозы при физическом и эмоциональном перенапряжении, изменении режима питания. Во время лечения не рекомендуется принимать алкоголь. За 48 часов до хирургического вмешательства или внутривенного введения йодсодержащего рентгеноконтрастного средства прием препарата Глюконорм следует прекратить. Лечение препаратом Глюконорм рекомендуется возобновить через 48 часов."},{"name":"Взаимодействие","value":"Взаимодействие с другими лекарственными средствами\u003Cbr\u003EУсиливают гипогликемическое действие препарата ингибиторы ангиотензин- превращающего фермента (каптоприл, эналаприл), блокаторы Н2-гистаминовых рецепторов (циметидин), противогрибковые лекарственные средства (миконазол, флуконазол), нестероидные противовоспалительные препараты (НПВП) (фенилбутазон, азапропазон, оксифенбутазон), фибраты (клофибрат, безафибрат), противотуберкулезные (этионамид), салицилаты, антикоагулянты кумаринового ряда, анаболические стероиды, бета-адреноблокаторы, ингибиторы моноаминооксидазы, сульфаниламиды длительного действия, циклофосфамид, хлорамфеникол, фенфлурамин, флуоксетин, гуанетидин, пентоксифиллин, тетрациклин, теофиллин, блокаторы канальциевой секреции, резерпин, бромокриптин, дизопирамид, пиридоксин, другие гипогликемические препараты (акарбоза, бигуаниды, инсулин и др.), аллопуринол.\u003Cbr\u003EОслабляют эффект барбитураты, глюкокортикостероиды, адреностимуляторы (эпинефрин, клонидин), противоэпилептические препараты (фенитоин), блокаторы \"медленных\" кальциевых каналов, ингибиторы карбоангидразы (ацетазоламид), тиазидные диуретики, хлорталидон, фуросемид, триамтерен, аспарагиназа, баклофен, даназол, диазоксид, изониазид, морфин, ритодрин, сальбутамол, тербуталин, глюкагон, рифампицин, йодсодержащие гормоны щитовидной железы, соли лития, в высоких дозах - никотиновая кислота, хлорпромазин, пероральные контрацептивы и эстрогены.\u003Cbr\u003EПодкисляющие мочу лекарственные средства (аммония хлорид, кальция хлорид, аскорбиновая кислота в больших дозах) усиливают действие за счет уменьшения степени диссоциации и повышения реабсорбции глибенкламида.\u003Cbr\u003EЭтанол усиливает вероятность развития лактоацидоза.\u003Cbr\u003EМетформин уменьшает максимальную концентрацию в крови (Сmах) и Т1/2 фуросемида на 31 и 42,3 % соответственно.\u003Cbr\u003EФуросемид увеличивает Сmах метформина на 22 %.\u003Cbr\u003EНифедипин повышает абсорбцию, Сmах, замедляет выведение метформина.\u003Cbr\u003EКатионные лекарственные средства (амилорид, дигоксин, морфин, прокаинамид, хинидин, хинин, ранитидин, триамтерен и ванкомицин), секретирующиеся в канальцах, конкурируют за канальциевые транспортные системы и при длительной терапии могут увеличить Сmах метформина на 60 %."},{"name":"Регистрационный номер","value":"ЛCP-009610/09"},{"name":"Дата государственной регистрации","value":"10.06.2010"},{"name":"Владелец регистрационного удостоверения","value":"M.J.Biopharm"},{"name":"Изготовитель","value":"M.J.Biopharm"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Глюконорм"},{"name":"Срок годности","value":"35 мес."}]}],"transitionId":"tr_13431602956594298390"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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246 ₽

Скидка: 17%
–17 %
Вместо:296 ₽
  • 11-13 июня, самовывоз • 0 ₽
POLZAru
Рейтинг 4.9 из 5
38Котзывов
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  • Субетта таб. д/рассас., 100 шт.
    –2 %
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    Субетта таб. д/рассас., 100 шт.

    Рейтинг товара: 4.8 из 5
    на основе 13 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 598 ₽ вместо 610
    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таб. д/рассас., 100 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  • Глюкованс таб. п/о плен., 5 мг+500 мг, 30 шт.
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    Глюкованс таб. п/о плен., 5 мг+500 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 10 оценок
    Цена 478 ₽
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  • Глюконорм плюс таб. п/о плен., 5 мг+500 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-u6s46gqraq8/toggleWishlist":{"skuId":"228044141","productId":998360042,"offerId":"4WzN8Lt9L2anFo2X5dZ35Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQo52Yrs6BytuHARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIVCOqHh9wDEO3a3mwY/sPZByDe2cEH","sign":"e7gl7xpRGjnCiWq3mjMeNRlbkATl2Rm0sivLtuI7vS0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-u6s46gqraq8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Глюконорм плюс таб. п/о плен., 5 мг+500 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 6 оценок
    Цена 303 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-u6s46gqraq8/addToCartButton":{"offerId":"4WzN8Lt9L2anFo2X5dZ35Q","skuId":"228044141","pendingCartItem":{"productId":998360042,"offerId":"4WzN8Lt9L2anFo2X5dZ35Q","showPlaceId":"OTNDnItfwRMjN9MRHuEMMsJVHK543kRXmqUCK2YjLl26xB4wD_-NaZxZUY4niPzUQU867E2w-HCm5j24UgodvK7ssxKwJmwjNXwSSqC-lVimB7r5qj66m-MNpPPK1DUC5Ov6rhKL0Ui8m93s0coeBQv7QQk5wINFz0l-eN94Ugml2ATuX5AM_YT42-OWDVF1GHh5IKSbqEMCeeRqprJHkg,,","feeShow":"OTNDnItfwRMjN9MRHuEMMsJVHK543kRXmqUCK2YjLl26xB4wD_-NaZxZUY4niPzUQU867E2w-HCm5j24UgodvK7ssxKwJmwjNXwSSqC-lVimB7r5qj66m-MNpPPK1DUC5Ov6rhKL0Ui8m93s0coeBQv7QQk5wINFz0l-eN94Ugml2ATuX5AM_YT42-OWDVF1GHh5IKSbqEMCeeRqprJHkg,,","skuId":"228044141","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"303","currency":"RUR"},"hid":"15756510","name":"Глюконорм плюс таб. п/о плен., 5 мг+500 мг, 30 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  • Диабетон МВ таб. модиф. высвоб., 60 мг, 30 шт.
    –20 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-tqtc6m8hcm/toggleWishlist":{"skuId":"452783006","productId":1778172473,"offerId":"vXC_nG8AMFwyuZv3HbDd_g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQo52Yrs6BytuHARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIWCLmE888GEJ7X89cBGKXe0Acg3tnBBw==","sign":"mR8KNuHy0LBayz1N32pkvH4IcYQaYGoin4xEjqdItDc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-tqtc6m8hcm/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Диабетон МВ таб. модиф. высвоб., 60 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 14 оценок
    Цена 245 ₽ вместо 306
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  • Глибомет таб. п/о плен., 2.5 мг+400 мг, 40 шт.
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    Глибомет таб. п/о плен., 2.5 мг+400 мг, 40 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 616 ₽
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  • Сиофор таб. п/о плен., 1000 мг, 60 шт.
    –20 %
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    Сиофор таб. п/о плен., 1000 мг, 60 шт.

    Рейтинг товара: 4.8 из 5
    на основе 39 оценок
    Цена 209 ₽ вместо 261
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  • Галвус таб., 50 мг, 28 шт.
    –10 %
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    Галвус таб., 50 мг, 28 шт.

    Рейтинг товара: 4.9 из 5
    на основе 43 оценки
    Цена 824 ₽ вместо 915
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  • Гликлазид-СЗ таб. пролонг. высвоб., 60 мг, 30 шт.
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    Гликлазид-СЗ таб. пролонг. высвоб., 60 мг, 30 шт.

    Рейтинг товара: 3.7 из 5
    на основе 6 оценок
    Цена 132 ₽
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  • Сиофор таб. п/о плен., 850 мг, 60 шт.
    –18 %
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    Сиофор таб. п/о плен., 850 мг, 60 шт.

    Рейтинг товара: 4.8 из 5
    на основе 18 оценок
    Цена 174 ₽ вместо 211
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  • Глибенкламид + Метформин таб. п/о плен., 2.5 мг+500 мг, 30 шт.
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    Глибенкламид + Метформин таб. п/о плен., 2.5 мг+500 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 273 ₽
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  • Глидиаб МВ таб. модиф. высвоб., 30 мг, 60 шт.
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    Глидиаб МВ таб. модиф. высвоб., 30 мг, 60 шт.

    Рейтинг товара: 4.9 из 5
    на основе 15 оценок
    Цена 151 ₽
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{"widgets":{"@light/ScrollBoxControls":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/controls":{"parentId":"09wrnzh8j9to","itemsCount":12,"ratio":[2,13],"withScrollBoxGap":false,"gapWidth":4,"rightButtonOffset":0,"leftButtonOffset":0}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/controls":{"name":"@light/ScrollBoxControls"}}}

Инструкция

Показания к применению

Сахарный диабет 2 типа у взрослых:
-при неэффективности диетотерапии, физических упражнений и предшествующей терапии метформином или глибенкламидом;
-для замещения предшествующей терапии двумя препаратами (метформином и глибенкламидом) у больных со стабильным и хорошо контролируемым уровнем глюкозы крови.

Противопоказания

- Повышенная чувствительность к метформину, глибенкламиду или другим производным сульфонилмочевины, а также к вспомогательным веществам;
- сахарный диабет 1 типа;
- диабет ический кетоацидоз, диабетическая прекома, диабетическая кома;
- гипогликемия:
- тяжелые нарушения функции почек;
- острые состояния, которые могут приводить к изменению функции почек: дегидратация, тяжелая инфекция, шок;
- острые или хронические заболевания, сопровождающиеся гипоксией тканей: сердечная или дыхательная недостаточность, недавний инфаркт миокарда, шок;
- печеночная недостаточность;
- порфирия;
- беременность, период грудного вскармливания;
- одновременный прием миконазола;
- инфекционные заболевания, большие хирургические вмешательства, травмы, обширные ожоги и другие состояния, требующие проведения инсулинотерапии;
- хронический алкоголизм, острая алкогольная интоксикация:
- лактоацидоз (в т.ч. в анамнезе);
- применение в течение не менее 48 часов до и в течение 48 часов после проведения радиоизотопных или рентгенологических исследований с введением йодсодержащего контрастного вещества;
- соблюдение гипокалорийной диеты (менее 1000 кал/сут).
Не рекомендуется применять препарат у лиц старше 60 лет, выполняющих тяжелую физическую работу, что связано с повышенным риском развития у них лактоацидоза.
С осторожностью:
Лихорадочный синдром, надпочечниковая недостаточность, гипофункция передней доли гипофиза, заболевания щитовидной железы с нарушением ее функции.

Способ применения и дозы

Препарат применяют внутрь, во время еды. Доза препарата определяется врачом индивидуально для каждого пациента в зависимости от концентрации глюкозы в крови. Обычно начальная доза составляет 1 таблетку в день. Каждые 1-2 недели после начала лечения дозу препарата корректируют в зависимости от концентрации глюкозы в крови. При замещении предшествующей комбинированной терапии метформином и глибекламидом назначают 1-2 таблетки препарата Глюконорм, в зависимости от предыдущей дозы каждого компонента. Максимальная суточная доза составляет 5 таблеток.
Полная инструкция
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Глюконорм таб. п/о плен.
Глюконорм таб. п/о плен., 2.5 мг+400 мг, 40 шт.
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У продавца:8 оценок·2 отзыва
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3 месяца назад • Александр Скулаков • Куплен на Маркете
Достоинства: Выполняет свою функцию
Комментарий: Аналог более дорогого препарата - глибомета.
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9 месяцев назад • Сергей Р. • Куплен на Маркете
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