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Описание

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Рамиприл-Акрихин таб., 5 мг, 30 шт.

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5.0
(1)
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Коротко о товаре

Артикул Маркета
3288356876
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"13324624693244028794":{"specItems":[{"name":"Артикул Маркета","value":"3288356876","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"артериальная гипертензия, диабетическая нефропатия, нефропатия, профилактика сердечно-сосудистых заболеваний, сердечная недостаточность, хроническая сердечная недостаточность","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["36476390:36618511,36618249,36618158,36617879,36617793,36617310"]}}},{"name":"действующее вещество","value":"Рамиприл","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28710604"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"таблетки"},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"13324624693244028794":{"specItems":[{"name":"Артикул Маркета","value":"3288356876","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Действующее вещество","value":"Рамиприл","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28710604"]}}},{"name":"Возраст","value":"От 18 лет"},{"name":"Форма выпуска","value":"Таблетки"}]}},"fullSpecs":{"13324624693244028794":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия, диабетическая нефропатия, нефропатия, профилактика сердечно-сосудистых заболеваний, сердечная недостаточность, хроническая сердечная недостаточность","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["36476390:36618511,36618249,36618158,36617879,36617793,36617310"]}}},{"name":"Показания к применению","value":"Артериальная гипертензия; хроническая сердечная недостаточность; сердечная недостаточность, развившаяся в первые несколько дней после острого инфаркта миокарда; диабетическая и недиабетическая нефропатия; снижение риска развития инфаркта миокарда, инсульта и сердечно-сосудистой смертности у пациентов с высоким сердечно-сосудистым риском, включая пациентов с подтвержденной ИБС (с инфарктом в анамнезе или без него), пациентов, перенесших чрескожную транслюминальную коронарную ангиопластику, коронарное шунтирование, с инсультом в анамнезе и пациентов с окклюзионными поражениями периферических артерий."},{"name":"Противопоказания","value":"Выраженные нарушения функции почек и печени, двусторонний стеноз почечных артерий или стеноз артерии единственной почки; состояние после трансплантации почки; первичный гиперальдостеронизм, гиперкалиемия, стеноз устья аорты, беременность, лактация (грудное вскармливание), детский и подростковый возраст до 18 лет, повышенная чувствительность к рамиприлу и другим ингибиторам АПФ."},{"name":"Состав","value":"Одна таблетка 1,25 мг/2,5 мг содержит:\u003Cbr /\u003Eдействующее вещество: рамиприл в пересчете на 100 % вещество - 1,25 мг/2,5 мг;\u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат, натрия гидрокарбонат, целлюлоза мик­рокристаллическая, гипромеллоза (тип 2910), аргинин, кроскармеллоза натрия, кремния диоксид коллоидный, кремния диоксид метилированный (кремния диоксид коллоидный гидрофобный), натрия стеарилфумарат, краситель железа оксид желтый.\u003Cbr /\u003EОдна таблетка 5 мг/10 мг содержит:\u003Cbr /\u003Eдействующее вещество: рамиприл в пересчете на 100 % вещество - 5 мг/10 мг;\u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат, натрия гидрокарбонат, целлюлоза мик­рокристаллическая, гипромеллоза (тип 2910), аргинин, кроскармеллоза натрия, кремния диоксид коллоидный, кремния диоксид метилированный (кремния диоксид коллоидный гидрофобный), натрия стеарилфумарат, краситель железа оксид красный.\u003Cbr /\u003E"},{"name":"Действующее вещество","value":"Рамиприл","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28710604"]}}},{"name":"Способ применения и дозы","value":"Принимают внутрь. Начальная доза - 1.25-2.5 мг 1-2 раза/сут. При необходимости возможно постепенное повышение дозы. Поддерживающая доза устанавливается индивидуально, в зависимости от показаний к применению и эффективности лечения."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: артериальная гипотензия; редко - боли в груди, тахикардия.\u003Cbr\u003EСо стороны ЦНС: головокружение, слабость, головная боль; редко - нарушения сна, настроения.\u003Cbr\u003EСо стороны системы пищеварения: диарея, запор, потеря аппетита; редко - стоматит, боли в животе, панкреатит, холестатическая желтуха.\u003Cbr\u003EСо стороны дыхательной системы: сухой кашель, бронхит, синусит.\u003Cbr\u003EСо стороны мочевыделительной системы: редко - протеинурия, повышение концентрации креатинина и мочевины в крови (главным образом у пациентов с нарушением функции почек).\u003Cbr\u003EСо стороны системы кроветворения: редко - нейтропения, агранулоцитоз, тромбоцитопения, анемия.\u003Cbr\u003EСо стороны лабораторных показателей: гипокалиемия, гипонатриемия.\u003Cbr\u003EАллергические реакции: кожная сыпь, ангионевротический отек и другие реакции гиперчувствительности.\u003Cbr\u003EПрочие: редко - мышечные спазмы, импотенция, алопеция."},{"name":"Фармакологическое действие","value":"Ингибитор АПФ. Является пролекарством, из которого в организме образуется активный метаболит рамиприлат. Полагают, что механизм антигипертензивного действия связан с конкурентным ингибированием активности АПФ, которое приводит к снижению скорости превращения ангиотензина I в ангиотензин II, являющийся мощным сосудосуживающим веществом. В результате уменьшения концентрации ангиотензина II происходит вторичное увеличение активности ренина плазмы за счет устранения отрицательной обратной связи при высвобождении ренина и прямое снижение секреции альдостерона. Благодаря сосудорасширяющему действию уменьшает ОПСС (постнагрузку), давление заклинивания в легочных капиллярах (преднагрузку) и сопротивление в легочных сосудах; повышает минутный объем сердца и толерантность к нагрузке.\u003Cbr\u003EУ пациентов с признаками хронической сердечной недостаточности после инфаркта миокарда рамиприл снижает риск внезапной смерти, прогрессирование сердечной недостаточности в тяжелую/резистентную недостаточность и уменьшает число госпитализаций по поводу сердечной недостаточности.\u003Cbr\u003EИзвестно, что рамиприл значительно снижает частоту инфаркта миокарда, инсульта и сердечно-сосудистой смерти у пациентов с повышенным кардиоваскулярным риском вследствие сосудистых заболеваний (ИБС, перенесенный инсульт или заболевания периферических сосудов) или сахарного диабета, у которых имеется как минимум один дополнительный фактор риска (микроальбуминурия, артериальная гипертензия, повышение уровня общего холестерина, низкий уровень ЛПВП, курение). Снижает общую смертность и потребность в процедурах по реваскуляризации, замедляет возникновение и прогрессирование хронической сердечной недостаточности. Как у пациентов с сахарным диабетом, так и без него, рамиприл значительно снижает имеющуюся микроальбуминурию и риск развития нефропатии. Эти эффекты отмечаются у пациентов как с повышенным, так и с нормальным АД.\u003Cbr\u003EГипотензивный эффект рамиприла развивается примерно через 1-2 ч, достигает максимума в пределах 3-6 ч, продолжается не менее 24 ч."},{"name":"Фармакологическая группа","value":"ингибиторы АПФ"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В сухом, защищенном от света месте при температуре не выше 25 °C. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Случаи передозировки препарата до настоящего времени зарегистрированы не были."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан при беременности, так как он может оказывать токсическое действие на плод:(нарушение развития почек, нарушение функции почек, олигогидрамнион, контрактура конечностей, деформация костей черепа, гипоплазия легких) и новорожденного (почечная недостаточность, олигурия, артериальная гипотензия, гиперкалиемия). Поэтому перед началом приема препарата у женщин репродуктивного возраста следует исключить беременность.\u003Cbr /\u003EЕсли женщина планирует беременность, то лечение ингибиторами АПФ должно быть прекращено.\u003Cbr /\u003EЕсли воздействие ингибиторов АПФ имело место во втором триместре беременности или на более поздних сроках, рекомендуется ультразвуковое исследование плода для контроля функции почек и состояния костей черепа. Новорожденных, чьи матери во время беременности принимали ингибиторы АПФ, необходимо тщательно наблюдать из-за риска развития артериальной гипотензии, олигурии и гиперкалиемии.\u003Cbr /\u003EВ случае подтверждения факта беременности во время лечения препаратом Рамиприл-Акрихин следует как можно скорее прекратить его прием и перевести пациентку на прием других препаратов, при применении которых риск для ребенка будет наименьшим.\u003Cbr /\u003EЕсли лечение препаратом Рамиприл-Акрихин необходимо в период грудного вскармливания, то грудное вскармливание должно быть прекращено.\u003Cbr /\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения препаратом Рамиприл-Акрихин необходимо воздерживаться от занятий потенциально опасными видами деятельности, включая управление транспортными средствами, требующими повышенной концентрации внимания и быстроты реакций, т.к. на фоне его приема возможно появление головокружения, снижение быстроты психомоторных реакций, внимания, особенно после приема первой дозы препарата."},{"name":"Особые указания","value":"У пациентов с сопутствующим нарушением функции почек дозы подбирают индивидуально в соответствии со значениями КК. Перед началом лечения всем больным необходимо проведение исследования функции почек. В процессе лечения рамиприлом регулярно осуществляется контроль функции почек, электролитного состава крови, уровня печеночных ферментов в крови, а также картины периферической крови (особенно у пациентов с диффузными заболеваниями соединительной ткани, у пациентов, получающих иммунодепрессанты, аллопуринол). Больным, у которых имеется дефицит жидкости и/или натрия, перед началом лечения необходимо провести коррекцию водно-электролитных нарушений. Во время лечения рамиприлом нельзя проводить гемодиализ с использованием полиакрилонитрильных мембран (повышен риск возникновения анафилактических реакций)."},{"name":"Взаимодействие","value":"При одновременном применении калийсберегающих диуретиков (в т.ч. спиронолактона, триамтерена, амилорида), препаратов калия, заменителей соли и БАД к пище, содержащих калий, возможно развитие гиперкалиемии (особенно у пациентов с нарушениями функции почек), т.к. ингибиторы АПФ уменьшают содержание альдостерона, что приводит к задержке калия в организме на фоне ограничения выведения калия или его дополнительного поступления в организм.\u003Cbr\u003EПри одновременном применении с НПВС возможно уменьшение гипотензивного эффекта рамиприла, нарушение функции почек.\u003Cbr\u003EПри одновременном применении с \"петлевыми\" или тиазидными диуретиками усиливается антигипертензивное действие. Выраженная артериальная гипотензия, особенно после приема первой дозы диуретика, по-видимому, возникает за счет гиповолемии, которая приводит к транзиторному усилению гипотензивного эффекта рамиприла. Имеется риск развития гипокалиемии. Повышается риск нарушения функции почек.\u003Cbr\u003EПри одновременном применении со средствами, оказывающими гипотензивный эффект, возможно усиление гипотензивного эффекта.\u003Cbr\u003EПри одновременном применении с инсулином, гипогликемическими средствами производными сульфонилмочевины, метформином возможно развитие гипогликемии.\u003Cbr\u003EПри одновременном применении с аллопуринолом, цистостатиками, иммунодепрессантами, прокаинамидом возможно повышение риска развития лейкопении.\u003Cbr\u003EПри одновременном применении с лития карбонатом возможно повышение концентрации лития в сыворотке крови."},{"name":"Регистрационный номер","value":"ЛП-002791"},{"name":"Дата государственной регистрации","value":"30.12.2019"},{"name":"Владелец регистрационного удостоверения","value":"АКРИХИН","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:11037214"]}}},{"name":"Изготовитель","value":"АКРИХИН"},{"name":"Фасовщик","value":"АКРИХИН"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Рамиприл-Акрихин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:17998906"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"13324624693244028794":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия, диабетическая нефропатия, нефропатия, профилактика сердечно-сосудистых заболеваний, сердечная недостаточность, хроническая сердечная недостаточность"},{"name":"Показания к применению","value":"Артериальная гипертензия; хроническая сердечная недостаточность; сердечная недостаточность, развившаяся в первые несколько дней после острого инфаркта миокарда; диабетическая и недиабетическая нефропатия; снижение риска развития инфаркта миокарда, инсульта и сердечно-сосудистой смертности у пациентов с высоким сердечно-сосудистым риском, включая пациентов с подтвержденной ИБС (с инфарктом в анамнезе или без него), пациентов, перенесших чрескожную транслюминальную коронарную ангиопластику, коронарное шунтирование, с инсультом в анамнезе и пациентов с окклюзионными поражениями периферических артерий."},{"name":"Противопоказания","value":"Выраженные нарушения функции почек и печени, двусторонний стеноз почечных артерий или стеноз артерии единственной почки; состояние после трансплантации почки; первичный гиперальдостеронизм, гиперкалиемия, стеноз устья аорты, беременность, лактация (грудное вскармливание), детский и подростковый возраст до 18 лет, повышенная чувствительность к рамиприлу и другим ингибиторам АПФ."},{"name":"Состав","value":"Одна таблетка 1,25 мг/2,5 мг содержит:\u003Cbr /\u003Eдействующее вещество: рамиприл в пересчете на 100 % вещество - 1,25 мг/2,5 мг;\u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат, натрия гидрокарбонат, целлюлоза мик­рокристаллическая, гипромеллоза (тип 2910), аргинин, кроскармеллоза натрия, кремния диоксид коллоидный, кремния диоксид метилированный (кремния диоксид коллоидный гидрофобный), натрия стеарилфумарат, краситель железа оксид желтый.\u003Cbr /\u003EОдна таблетка 5 мг/10 мг содержит:\u003Cbr /\u003Eдействующее вещество: рамиприл в пересчете на 100 % вещество - 5 мг/10 мг;\u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат, натрия гидрокарбонат, целлюлоза мик­рокристаллическая, гипромеллоза (тип 2910), аргинин, кроскармеллоза натрия, кремния диоксид коллоидный, кремния диоксид метилированный (кремния диоксид коллоидный гидрофобный), натрия стеарилфумарат, краситель железа оксид красный.\u003Cbr /\u003E"},{"name":"Действующее вещество","value":"Рамиприл"},{"name":"Способ применения и дозы","value":"Принимают внутрь. Начальная доза - 1.25-2.5 мг 1-2 раза/сут. При необходимости возможно постепенное повышение дозы. Поддерживающая доза устанавливается индивидуально, в зависимости от показаний к применению и эффективности лечения."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: артериальная гипотензия; редко - боли в груди, тахикардия.\u003Cbr\u003EСо стороны ЦНС: головокружение, слабость, головная боль; редко - нарушения сна, настроения.\u003Cbr\u003EСо стороны системы пищеварения: диарея, запор, потеря аппетита; редко - стоматит, боли в животе, панкреатит, холестатическая желтуха.\u003Cbr\u003EСо стороны дыхательной системы: сухой кашель, бронхит, синусит.\u003Cbr\u003EСо стороны мочевыделительной системы: редко - протеинурия, повышение концентрации креатинина и мочевины в крови (главным образом у пациентов с нарушением функции почек).\u003Cbr\u003EСо стороны системы кроветворения: редко - нейтропения, агранулоцитоз, тромбоцитопения, анемия.\u003Cbr\u003EСо стороны лабораторных показателей: гипокалиемия, гипонатриемия.\u003Cbr\u003EАллергические реакции: кожная сыпь, ангионевротический отек и другие реакции гиперчувствительности.\u003Cbr\u003EПрочие: редко - мышечные спазмы, импотенция, алопеция."},{"name":"Фармакологическое действие","value":"Ингибитор АПФ. Является пролекарством, из которого в организме образуется активный метаболит рамиприлат. Полагают, что механизм антигипертензивного действия связан с конкурентным ингибированием активности АПФ, которое приводит к снижению скорости превращения ангиотензина I в ангиотензин II, являющийся мощным сосудосуживающим веществом. В результате уменьшения концентрации ангиотензина II происходит вторичное увеличение активности ренина плазмы за счет устранения отрицательной обратной связи при высвобождении ренина и прямое снижение секреции альдостерона. Благодаря сосудорасширяющему действию уменьшает ОПСС (постнагрузку), давление заклинивания в легочных капиллярах (преднагрузку) и сопротивление в легочных сосудах; повышает минутный объем сердца и толерантность к нагрузке.\u003Cbr\u003EУ пациентов с признаками хронической сердечной недостаточности после инфаркта миокарда рамиприл снижает риск внезапной смерти, прогрессирование сердечной недостаточности в тяжелую/резистентную недостаточность и уменьшает число госпитализаций по поводу сердечной недостаточности.\u003Cbr\u003EИзвестно, что рамиприл значительно снижает частоту инфаркта миокарда, инсульта и сердечно-сосудистой смерти у пациентов с повышенным кардиоваскулярным риском вследствие сосудистых заболеваний (ИБС, перенесенный инсульт или заболевания периферических сосудов) или сахарного диабета, у которых имеется как минимум один дополнительный фактор риска (микроальбуминурия, артериальная гипертензия, повышение уровня общего холестерина, низкий уровень ЛПВП, курение). Снижает общую смертность и потребность в процедурах по реваскуляризации, замедляет возникновение и прогрессирование хронической сердечной недостаточности. Как у пациентов с сахарным диабетом, так и без него, рамиприл значительно снижает имеющуюся микроальбуминурию и риск развития нефропатии. Эти эффекты отмечаются у пациентов как с повышенным, так и с нормальным АД.\u003Cbr\u003EГипотензивный эффект рамиприла развивается примерно через 1-2 ч, достигает максимума в пределах 3-6 ч, продолжается не менее 24 ч."},{"name":"Фармакологическая группа","value":"ингибиторы АПФ"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В сухом, защищенном от света месте при температуре не выше 25 °C. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Случаи передозировки препарата до настоящего времени зарегистрированы не были."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан при беременности, так как он может оказывать токсическое действие на плод:(нарушение развития почек, нарушение функции почек, олигогидрамнион, контрактура конечностей, деформация костей черепа, гипоплазия легких) и новорожденного (почечная недостаточность, олигурия, артериальная гипотензия, гиперкалиемия). Поэтому перед началом приема препарата у женщин репродуктивного возраста следует исключить беременность.\u003Cbr /\u003EЕсли женщина планирует беременность, то лечение ингибиторами АПФ должно быть прекращено.\u003Cbr /\u003EЕсли воздействие ингибиторов АПФ имело место во втором триместре беременности или на более поздних сроках, рекомендуется ультразвуковое исследование плода для контроля функции почек и состояния костей черепа. Новорожденных, чьи матери во время беременности принимали ингибиторы АПФ, необходимо тщательно наблюдать из-за риска развития артериальной гипотензии, олигурии и гиперкалиемии.\u003Cbr /\u003EВ случае подтверждения факта беременности во время лечения препаратом Рамиприл-Акрихин следует как можно скорее прекратить его прием и перевести пациентку на прием других препаратов, при применении которых риск для ребенка будет наименьшим.\u003Cbr /\u003EЕсли лечение препаратом Рамиприл-Акрихин необходимо в период грудного вскармливания, то грудное вскармливание должно быть прекращено.\u003Cbr /\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения препаратом Рамиприл-Акрихин необходимо воздерживаться от занятий потенциально опасными видами деятельности, включая управление транспортными средствами, требующими повышенной концентрации внимания и быстроты реакций, т.к. на фоне его приема возможно появление головокружения, снижение быстроты психомоторных реакций, внимания, особенно после приема первой дозы препарата."},{"name":"Особые указания","value":"У пациентов с сопутствующим нарушением функции почек дозы подбирают индивидуально в соответствии со значениями КК. Перед началом лечения всем больным необходимо проведение исследования функции почек. В процессе лечения рамиприлом регулярно осуществляется контроль функции почек, электролитного состава крови, уровня печеночных ферментов в крови, а также картины периферической крови (особенно у пациентов с диффузными заболеваниями соединительной ткани, у пациентов, получающих иммунодепрессанты, аллопуринол). Больным, у которых имеется дефицит жидкости и/или натрия, перед началом лечения необходимо провести коррекцию водно-электролитных нарушений. Во время лечения рамиприлом нельзя проводить гемодиализ с использованием полиакрилонитрильных мембран (повышен риск возникновения анафилактических реакций)."},{"name":"Взаимодействие","value":"При одновременном применении калийсберегающих диуретиков (в т.ч. спиронолактона, триамтерена, амилорида), препаратов калия, заменителей соли и БАД к пище, содержащих калий, возможно развитие гиперкалиемии (особенно у пациентов с нарушениями функции почек), т.к. ингибиторы АПФ уменьшают содержание альдостерона, что приводит к задержке калия в организме на фоне ограничения выведения калия или его дополнительного поступления в организм.\u003Cbr\u003EПри одновременном применении с НПВС возможно уменьшение гипотензивного эффекта рамиприла, нарушение функции почек.\u003Cbr\u003EПри одновременном применении с \"петлевыми\" или тиазидными диуретиками усиливается антигипертензивное действие. Выраженная артериальная гипотензия, особенно после приема первой дозы диуретика, по-видимому, возникает за счет гиповолемии, которая приводит к транзиторному усилению гипотензивного эффекта рамиприла. Имеется риск развития гипокалиемии. Повышается риск нарушения функции почек.\u003Cbr\u003EПри одновременном применении со средствами, оказывающими гипотензивный эффект, возможно усиление гипотензивного эффекта.\u003Cbr\u003EПри одновременном применении с инсулином, гипогликемическими средствами производными сульфонилмочевины, метформином возможно развитие гипогликемии.\u003Cbr\u003EПри одновременном применении с аллопуринолом, цистостатиками, иммунодепрессантами, прокаинамидом возможно повышение риска развития лейкопении.\u003Cbr\u003EПри одновременном применении с лития карбонатом возможно повышение концентрации лития в сыворотке крови."},{"name":"Регистрационный номер","value":"ЛП-002791"},{"name":"Дата государственной регистрации","value":"30.12.2019"},{"name":"Владелец регистрационного удостоверения","value":"АКРИХИН"},{"name":"Изготовитель","value":"АКРИХИН"},{"name":"Фасовщик","value":"АКРИХИН"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Рамиприл-Акрихин"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_4010699607089860962"}}}}
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    на основе 12 оценок
    Цена 73 ₽
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  • Рамиприл таб., 2.5 мг, 28 шт.
    –36 %
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    Рамиприл таб., 2.5 мг, 28 шт.

    Рейтинг товара: 4.7 из 5
    на основе 18 оценок
    Цена 90 ₽ вместо 140
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  • Рамиприл таб., 5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-en0olxhejq4/toggleWishlist":{"skuId":"647080079","productId":1401075906,"offerId":"uk9xL7n5MaXo5US1U7kP3g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQu4aWi6rqor9gEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIwvGKnAUQj9HGtAIYsc2dBSDX3MEH","sign":"BdzngT8+812x9xR7Z6+k8n4bTHs9DZgeR0rGxpoU1fI="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-en0olxhejq4/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Рамиприл таб., 5 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 21 оценка
    Цена 138 ₽
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  • Рамиприл-СЗ таб., 5 мг, 30 шт.
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    Рамиприл-СЗ таб., 5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 79 ₽
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  • Рамиприл-ВЕРТЕКС капс., 5 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gayjfgw2z17/toggleWishlist":{"skuId":"661005021","productId":1401075925,"offerId":"iVQCmlJCXqcI7PQq-Ym4aw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQu4aWi6rqor9gEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI1fGKnAUQ3cWYuwIYtNWHBCDX3MEH","sign":"4nTBF5PB9g4IbJqVm8TIIxhKHFavtjs5OvXWOg9rxkc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gayjfgw2z17/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Рамиприл-ВЕРТЕКС капс., 5 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 152 ₽
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  • Хартил таб., 5 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-az5koqc6j0h/toggleWishlist":{"skuId":"228095646","productId":1401075629,"offerId":"grhSJ6qYwyQqDYF473BB4w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQu4aWi6rqor9gEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIre+KnAUQnu3hbBiS3dAHINfcwQc=","sign":"LLxLE/HwN9VSFKpPWU46rlcLmXUO2ZIDi3NLknp/dNg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-az5koqc6j0h/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Хартил таб., 5 мг, 28 шт.

    Рейтинг товара: 4.8 из 5
    на основе 87 оценок
    Цена 153 ₽
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  • Моксонидин-Акрихин таб. п/о плен., 0.2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vhvlebf1v8h/toggleWishlist":{"skuId":"834997635","productId":1401075967,"offerId":"YCynmt7uRtWY2jjYa8AlDg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQu4aWi6rqor9gEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI//GKnAUQg5uUjgMYntShBSDX3MEH","sign":"wJoEQ+xOxgdqJgsulGs8IXGjYWH9eHxV+0rcTun2Zmk="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vhvlebf1v8h/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин-Акрихин таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 6 оценок
    Цена 249 ₽
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  • Метопролол-Акрихин таб., 50 мг, 30 шт.
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    Метопролол-Акрихин таб., 50 мг, 30 шт.

    Рейтинг товара: 3 из 5
    на основе 2 оценки
    Цена 86 ₽
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  • Аторвастатин таб. п/о плен., 20 мг, 90 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-c8ee9zgkrue/toggleWishlist":{"skuId":"228018694","productId":1401075579,"offerId":"cKP9oDk7TeOlOfgnOtALpQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQu4aWi6rqor9gEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI++6KnAUQhpTdbBjHotUHINfcwQc=","sign":"AVOcwBi9AD5bCVoc1dUrDx6ZJ+zUzQOdUN6YXwI23cY="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-c8ee9zgkrue/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Аторвастатин таб. п/о плен., 20 мг, 90 шт.

    Рейтинг товара: 5 из 5
    на основе 13 оценок
    Цена 945 ₽
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  • Амприлан таб., 10 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rw7q86oauns/toggleWishlist":{"skuId":"228004018","productId":1401075686,"offerId":"Wwg9wackivrgnameMgDu_Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQu4aWi6rqor9gEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI5u+KnAUQsqHcbBi21YcEINfcwQc=","sign":"VLKw0wi5UBeTJ6XxRg0L81qGy2CSsCJzWWIBbRasvog="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rw7q86oauns/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Амприлан таб., 10 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 199 ₽
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  • Карведилол-Акрихин таб., 6.25 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qhrqse36zxt/toggleWishlist":{"skuId":"186852231","productId":1401075474,"offerId":"bDO0zrmmNXcfN-h0NfrKcg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQu4aWi6rqor9gEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIku6KnAUQh8eMWRie1KEFINfcwQc=","sign":"UTJLL5/fNv+38dLNXNdAaDl69gixr6GE9k11g2QS3Ms="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qhrqse36zxt/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Карведилол-Акрихин таб., 6.25 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 6 оценок
    Цена 204 ₽
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  • Лерникор таб. п/о плен., 10 мг, 30 шт.
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    Лерникор таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 3 оценки
    Цена 371 ₽
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Инструкция

Показания к применению

Артериальная гипертензия; хроническая сердечная недостаточность; сердечная недостаточность, развившаяся в первые несколько дней после острого инфаркта миокарда; диабетическая и недиабетическая нефропатия; снижение риска развития инфаркта миокарда, инсульта и сердечно-сосудистой смертности у пациентов с высоким сердечно-сосудистым риском, включая пациентов с подтвержденной ИБС (с инфарктом в анамнезе или без него), пациентов, перенесших чрескожную транслюминальную коронарную ангиопластику, коронарное шунтирование, с инсультом в анамнезе и пациентов с окклюзионными поражениями периферических артерий.

Противопоказания

Выраженные нарушения функции почек и печени, двусторонний стеноз почечных артерий или стеноз артерии единственной почки; состояние после трансплантации почки; первичный гиперальдостеронизм, гиперкалиемия, стеноз устья аорты, беременность, лактация (грудное вскармливание), детский и подростковый возраст до 18 лет, повышенная чувствительность к рамиприлу и другим ингибиторам АПФ.

Способ применения и дозы

Принимают внутрь. Начальная доза - 1.25-2.5 мг 1-2 раза/сут. При необходимости возможно постепенное повышение дозы. Поддерживающая доза устанавливается индивидуально, в зависимости от показаний к применению и эффективности лечения.
Полная инструкция
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Рамиприл-Акрихин таб.
Рамиприл-Акрихин таб., 5 мг, 30 шт.
5.0
(1)
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1 вопрос
Инструкция

145 ₽

Скидка: 26%
–26 %
Вместо:195 ₽
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