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Описание

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Монурал гран. д/приг. р-ра д/вн. приема, 3 г, 3 г, 1 шт.

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4.9
(40)
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Количество штук в упаковке, шт.: 1

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Коротко о товаре

Артикул Маркета
3123170392
Тип препарата
Назначение
Действующее вещество
Возраст
от 5 лет
Инструкция
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\u003Cbr /\u003E- бактериальный неспецифический уретрит; \u003Cbr /\u003E- бессимптомная массивная бактериурия у беременных; \u003Cbr /\u003E- послеоперационные инфекции мочевыводящих путей;\u003Cbr /\u003E- профилактика инфекций при хирургическом вмешательстве на мочевыводящих путях и при трансуретральных диагностических исследованиях.\u003Cbr /\u003E"},{"name":"Противопоказания","value":"- повышенная чувствительность к фосфомицину, другим компонентам препарата; \u003Cbr /\u003E- тяжелая почечная недостаточность (клиренс креатинина \u003C10 мл/мин), детский возраст до 12 лет (для дозировки 3 г); \u003Cbr /\u003E- детский возраст до 5 лет (для дозировки 2 г); \u003Cbr /\u003E- гемодиализ, дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция.\u003Cbr /\u003E"},{"name":"Состав","value":"1 пакет 6 г содержит: активное вещество - фосфомицина трометамол 3,754 г (эквивалентно 2,0 г фосфомицина); вспомогательные вещества: ароматизатор мандариновый 0,07 г, ароматизатор апельсиновый 0,06 г, сахарин 0,016 г, сахароза 2,100 г.\u003Cbr\u003E1 пакет 8 г содержит: активное вещество - фосфомицина трометамол 5,631 г (эквивалентно 3,0 г фосфомицина); вспомогательные вещества: ароматизатор мандариновый 0,07 г, ароматизатор апельсиновый 0,07 г, сахарин 0,016 г, сахароза 2,213 г."},{"name":"Действующее вещество","value":"Фосфомицин","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28710375"]}}},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EГранулы растворяют в 1/2 стакана воды (50 75 мл) или другого напитка, перемешивают до полного растворения, принимают сразу же после растворения. Монурал применяют один раз в сутки внутрь натощак за 1 час до или через 2-3 часа после еды, предпочтительно перед сном, предварительно опорожнив мочевой пузырь.\u003Cbr\u003EВзрослым и детям от 12 до 18 лет: по 1 пакету (3 г) 1 раз в день однократно.\u003Cbr\u003EС целью профилактики инфицирования мочевыводящих путей при хирургическом вмешательстве, трансуретральных диагностических процедурах Монурал принимают 2 раза по 3 г: за 3 часа до вмешательства и через 24 часа после вмешательства.\u003Cbr\u003EДетям от 5 лет до 12 лет: по 1 пакету (2 г) 1 раз в день однократно. С целью профилактики инфицирования мочевыводящих путей при хирургическом вмешательстве, трансуретральных диагностических процедурах Монурал принимают 2 раза по 2 г: за 3 часа до вмешательства и через 24 часа после вмешательства.\u003Cbr\u003EВ более тяжелых случаях (пожилые пациенты, рецидивирующие инфекции) принимают еще 1 пакет через 24 часа.\u003Cbr\u003EУ пациентов с легкой или средней степенью тяжести почечной недостаточности коррекция дозы не требуется. У пациентов с тяжелой почечной недостаточностью или находящихся на гемодиализе применение препарата противопоказано. У пациентов с печеночной недостаточностью коррекции дозы не требуется."},{"name":"Побочные действия","value":"Наиболее распространенными нежелательными реакциями на однократный прием фосфомицина являются нарушения со стороны желудочно- кишечного тракта, чаще всего диарея. Эти реакции являются кратковременными и проходят спонтанно. \u003Cbr\u003EДалее в таблице приведены неблагоприятные побочные реакции, которые были зарегистрированы при использовании препарата Монурал, в ходе клинических испытаний или пост-регистрационного наблюдения. Частота реакций указана следующим образом: очень часто (\u003E 1/10), часто (\u003E 1/100 до \u003C1/10), нечасто (\u003E 1/1000 до \u003C1/100), редко (\u003E 1/10000 до \u003C1/1000), очень редко (\u003C 1/10000) и неизвестно (частотность не может быть оценена на основе имеющихся данных). В каждой группе нежелательные реакции представлены в порядке убывания тяжести. \u003Cbr\u003E\nНарушения со стороны нервной системы: нечасто - Головная боль, головокружение; редко – Парестезии;\u003Cbr\u003EИнфекционные и паразитарные заболевания: нечасто - вульвовагинит редко – суперинфекция;\u003Cbr\u003EНарушения со стороны иммунной системы: неизвестно -анафилактические реакции, в том числе анафилактический шок, гиперчувствительность;\u003Cbr\u003EНарушения со стороны сердца: очень редко – тахикардия\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: неизвестно - астма, бронхоспазм, одышка;\u003Cbr\u003EНарушения со стороны желудочно -кишечного тракта: нечасто диарея, тошнота, диспепсия редко - абдоминальные боли, рвота; неизвестно - антибиотик -ассоциировэнный колит, снижение аппетита;\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: редко - сыпь, крапивница, зуд. Неизвестно- ангионевротический отёк;\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко- усталость;\u003Cbr\u003EНарушения со стороны сосудов неизвестно- снижение артериального давления, петехии;\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: неизвестно - кратковременное повышение активности щелочной фосфатазы и «печеночных» трансаминаз;\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: редко - апластическая анемия; неизвестно - эозинофилия, тромбоцитоз (петехии)."},{"name":"Фармакологическое действие","value":"Активное вещество Монуралан - фосфомицина трометамол - антибиотик широкого спектра, производное фосфоновой кислоты.\u003Cbr\u003EМонурал обладает бактерицидным действием. Механизм действия связан с подавлением первого этапа синтеза клеточной стенки бактерий. Являясь структурным аналогом фосфоэнола пирувата, вступает в конкурентное взаимодействие с ферментом N-ацетил-глюкозамино-З-о-энолпирувил- трансферазой, в результате чего происходит специфическое, избирательное и необратимое ингибирование этого фермента, что обеспечивает отсутствие перекрестной резистентности с другими классами антибиотиков и возможность синергизма с другими антибиотиками (in vitro отмечают синергизм с амоксициллином, цефалексином, пипемидиновой кислотой). Антибактериальный спектр действия фосфомицина трометамола in vitro включает большинство обычных грамположительных (Enterococcus spp., Enterococcus faecalis, Staphylococcus aureus, Staphylococcus saprophyt., Staphylococcus spp.) и грамотрицательных (E. coli, Citrobacter spp., Enterobacter spp., Klebsiella spp., Klebsiella pneumoniae, Morganella morganii, Proteus mirabilis, Pseudomonas spp., Serratia spp.) возбудителей. In vitro фосфомицина трометамол снижает адгезию ряда бактерий на эпителии мочевыводящих путей."},{"name":"Фармакологическая группа","value":"антибиотики"},{"name":"Форма выпуска","value":"гранулы"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 5 лет"},{"name":"Условия хранения","value":"Список Б. Хранить при температуре не выше 30 °С.\u003Cbr\u003EХранить в местах, недоступных для детей."},{"name":"Передозировка","value":"Данные в отношении передозировки фосфомицина для приема внутрь ограничены. У пациентов, принявших чрезмерную дозу препарата Монурал, наблюдались следующие реакции: нарушения функции вестибулярного аппарата, нарушения слуха, «металлический» привкус во рту, а также общее снижение восприятия вкуса.\u003Cbr\u003E Лечение при передозировке - симптоматическое и поддерживающее. В случае передозировки рекомендуется прием жидкости внутрь с целью увеличения диуреза."},{"name":"Применение при беременности и кормлении грудью","value":"При беременности препарат назначают только тогда, когда потенциальная польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПри необходимости назначения препарата в период лактации следует прекратить грудное вскармливание на время лечения."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Специальных\tисследований не проводилось, но пациентов следует информировать о том, что применение препарата может вызвать головокружение. При появлении головокружения следует воздержаться от выполнения указанных видов деятельности."},{"name":"Особые указания","value":"Во время лечения фосфомицином могут возникнуть реакции гиперчувствительности, включая анафилаксию и анафилактический шок, представляющие опасность для жизни. Если такая реакция возникает, необходимо исключить повторный прием фосфомицина и провести адекватное лечение. \u003Cbr\u003EАнтибиотик-ассоциированная диарея была отмечена при использовании практически всех антибактериальных средств, в том числе фосфомицина. Ее тяжесть может варьироваться от легкой диареи до смертельного колита. Диарея, в особенности тяжелая, непрекращающаяся и/или с кровью, во время или после лечения препаратом Монурал (в том числе, в течение нескольких недель после лечения), может быть симптомом заболевания, вызванного Clostridium difficile (псевдомембранозный колит). Этот диагноз важно учитывать при лечении пациентов во время или после приема препарата Монурал. При предполагаемом или подтвержденном диагнозе псевдомембранозного колита соответствующее лечение должно быть начато незамедлительно. \u003Cbr\u003EПрепараты, подавляющие перистальтику кишечника, в данной клинической ситуации противопоказаны. Почечная недостаточность: концентрация фосфомицина в моче сохраняется в течение 48 часов после приема обычной дозы, если клиренс креатинина выше 10 мл/мин. Препарат противопоказан пациентам, проходящим гемодиализ. \u003Cbr\u003EПациентам сахарным диабетом следует учитывать, что в 1 пакете препарата Монурал с дозировкой 2 г или 3 г фосфомицина содержится 2,100 г или 2,213 г сахарозы, соответственно. Пациентам с редкими наследственными заболеваниями, такими как непереносимость фруктозы, мальабсорбция глюкозы-галактозы или недостаточность сахаразы-изомальтазы, данный препарат противопоказан."},{"name":"Взаимодействие","value":"При совместном применении с фосфомицином, метоклопрамид снижает концентрацию фосфомицина в сыворотке крови и моче. Одновременное применение антацидов или солей кальция приводит к уменьшению концентрации фосфомицина в плазме крови и моче. \u003Cbr\u003EДругие препараты, которые увеличивают двигательную активность желудочно- кишечного тракта, могут вызывать аналогичный эффект. Возможны специфические проблемы, связанные с изменением международного нормализованного отношения (МНО). \u003Cbr\u003EУ пациентов, получающих антибиотики, были зарегистрированы, многочисленные случаи повышенной активности антагонистов антивитамина К. К факторам риска относятся тяжелая инфекция или воспаление, возраст и плохое общее состояние здоровья. В этих условиях трудно определить, является ли изменение в МНО следствием инфекционного заболевания или его лечения. Тем не менее, определенные классы антибиотиков чаще упоминаются в этой связи, а именно: фторхинолоны, макролиды, циклины, ко- тримоксазол и некоторые цефалоспорины."},{"name":"Регистрационный номер","value":"П N012976/01"},{"name":"Дата государственной регистрации","value":"11.07.2007"},{"name":"Владелец регистрационного удостоверения","value":"Zambon","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["34324371:35649313","7893318:16003054"]}}},{"name":"Изготовитель","value":"Zambon"},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Швейцария"},{"name":"Название препарата","value":"Монурал","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["17796364:18038408"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"5996325068758798474":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Назначение","value":"бессимптомная массивная бактериурия, инфекции мочевыводящих путей, послеоперационные инфекции, профилактика инфекций после хирургических операций, уретрит, цистит"},{"name":"Органы и системы","value":"выделительная система"},{"name":"Показания к применению","value":"Инфекционно-воспалительные заболевания, вызванные чувствительными к фосфомицину микроорганизмами: \u003Cbr /\u003E- острый бактериальный цистит, острые приступы рецидивирующего бактериального цистита; \u003Cbr /\u003E- бактериальный неспецифический уретрит; \u003Cbr /\u003E- бессимптомная массивная бактериурия у беременных; \u003Cbr /\u003E- послеоперационные инфекции мочевыводящих путей;\u003Cbr /\u003E- профилактика инфекций при хирургическом вмешательстве на мочевыводящих путях и при трансуретральных диагностических исследованиях.\u003Cbr /\u003E"},{"name":"Противопоказания","value":"- повышенная чувствительность к фосфомицину, другим компонентам препарата; \u003Cbr /\u003E- тяжелая почечная недостаточность (клиренс креатинина \u003C10 мл/мин), детский возраст до 12 лет (для дозировки 3 г); \u003Cbr /\u003E- детский возраст до 5 лет (для дозировки 2 г); \u003Cbr /\u003E- гемодиализ, дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция.\u003Cbr /\u003E"},{"name":"Состав","value":"1 пакет 6 г содержит: активное вещество - фосфомицина трометамол 3,754 г (эквивалентно 2,0 г фосфомицина); вспомогательные вещества: ароматизатор мандариновый 0,07 г, ароматизатор апельсиновый 0,06 г, сахарин 0,016 г, сахароза 2,100 г.\u003Cbr\u003E1 пакет 8 г содержит: активное вещество - фосфомицина трометамол 5,631 г (эквивалентно 3,0 г фосфомицина); вспомогательные вещества: ароматизатор мандариновый 0,07 г, ароматизатор апельсиновый 0,07 г, сахарин 0,016 г, сахароза 2,213 г."},{"name":"Действующее вещество","value":"Фосфомицин"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EГранулы растворяют в 1/2 стакана воды (50 75 мл) или другого напитка, перемешивают до полного растворения, принимают сразу же после растворения. Монурал применяют один раз в сутки внутрь натощак за 1 час до или через 2-3 часа после еды, предпочтительно перед сном, предварительно опорожнив мочевой пузырь.\u003Cbr\u003EВзрослым и детям от 12 до 18 лет: по 1 пакету (3 г) 1 раз в день однократно.\u003Cbr\u003EС целью профилактики инфицирования мочевыводящих путей при хирургическом вмешательстве, трансуретральных диагностических процедурах Монурал принимают 2 раза по 3 г: за 3 часа до вмешательства и через 24 часа после вмешательства.\u003Cbr\u003EДетям от 5 лет до 12 лет: по 1 пакету (2 г) 1 раз в день однократно. С целью профилактики инфицирования мочевыводящих путей при хирургическом вмешательстве, трансуретральных диагностических процедурах Монурал принимают 2 раза по 2 г: за 3 часа до вмешательства и через 24 часа после вмешательства.\u003Cbr\u003EВ более тяжелых случаях (пожилые пациенты, рецидивирующие инфекции) принимают еще 1 пакет через 24 часа.\u003Cbr\u003EУ пациентов с легкой или средней степенью тяжести почечной недостаточности коррекция дозы не требуется. У пациентов с тяжелой почечной недостаточностью или находящихся на гемодиализе применение препарата противопоказано. У пациентов с печеночной недостаточностью коррекции дозы не требуется."},{"name":"Побочные действия","value":"Наиболее распространенными нежелательными реакциями на однократный прием фосфомицина являются нарушения со стороны желудочно- кишечного тракта, чаще всего диарея. Эти реакции являются кратковременными и проходят спонтанно. \u003Cbr\u003EДалее в таблице приведены неблагоприятные побочные реакции, которые были зарегистрированы при использовании препарата Монурал, в ходе клинических испытаний или пост-регистрационного наблюдения. Частота реакций указана следующим образом: очень часто (\u003E 1/10), часто (\u003E 1/100 до \u003C1/10), нечасто (\u003E 1/1000 до \u003C1/100), редко (\u003E 1/10000 до \u003C1/1000), очень редко (\u003C 1/10000) и неизвестно (частотность не может быть оценена на основе имеющихся данных). В каждой группе нежелательные реакции представлены в порядке убывания тяжести. \u003Cbr\u003E\nНарушения со стороны нервной системы: нечасто - Головная боль, головокружение; редко – Парестезии;\u003Cbr\u003EИнфекционные и паразитарные заболевания: нечасто - вульвовагинит редко – суперинфекция;\u003Cbr\u003EНарушения со стороны иммунной системы: неизвестно -анафилактические реакции, в том числе анафилактический шок, гиперчувствительность;\u003Cbr\u003EНарушения со стороны сердца: очень редко – тахикардия\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: неизвестно - астма, бронхоспазм, одышка;\u003Cbr\u003EНарушения со стороны желудочно -кишечного тракта: нечасто диарея, тошнота, диспепсия редко - абдоминальные боли, рвота; неизвестно - антибиотик -ассоциировэнный колит, снижение аппетита;\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: редко - сыпь, крапивница, зуд. Неизвестно- ангионевротический отёк;\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко- усталость;\u003Cbr\u003EНарушения со стороны сосудов неизвестно- снижение артериального давления, петехии;\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: неизвестно - кратковременное повышение активности щелочной фосфатазы и «печеночных» трансаминаз;\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: редко - апластическая анемия; неизвестно - эозинофилия, тромбоцитоз (петехии)."},{"name":"Фармакологическое действие","value":"Активное вещество Монуралан - фосфомицина трометамол - антибиотик широкого спектра, производное фосфоновой кислоты.\u003Cbr\u003EМонурал обладает бактерицидным действием. Механизм действия связан с подавлением первого этапа синтеза клеточной стенки бактерий. Являясь структурным аналогом фосфоэнола пирувата, вступает в конкурентное взаимодействие с ферментом N-ацетил-глюкозамино-З-о-энолпирувил- трансферазой, в результате чего происходит специфическое, избирательное и необратимое ингибирование этого фермента, что обеспечивает отсутствие перекрестной резистентности с другими классами антибиотиков и возможность синергизма с другими антибиотиками (in vitro отмечают синергизм с амоксициллином, цефалексином, пипемидиновой кислотой). Антибактериальный спектр действия фосфомицина трометамола in vitro включает большинство обычных грамположительных (Enterococcus spp., Enterococcus faecalis, Staphylococcus aureus, Staphylococcus saprophyt., Staphylococcus spp.) и грамотрицательных (E. coli, Citrobacter spp., Enterobacter spp., Klebsiella spp., Klebsiella pneumoniae, Morganella morganii, Proteus mirabilis, Pseudomonas spp., Serratia spp.) возбудителей. In vitro фосфомицина трометамол снижает адгезию ряда бактерий на эпителии мочевыводящих путей."},{"name":"Фармакологическая группа","value":"антибиотики"},{"name":"Форма выпуска","value":"гранулы"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 5 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Список Б. Хранить при температуре не выше 30 °С.\u003Cbr\u003EХранить в местах, недоступных для детей."},{"name":"Передозировка","value":"Данные в отношении передозировки фосфомицина для приема внутрь ограничены. У пациентов, принявших чрезмерную дозу препарата Монурал, наблюдались следующие реакции: нарушения функции вестибулярного аппарата, нарушения слуха, «металлический» привкус во рту, а также общее снижение восприятия вкуса.\u003Cbr\u003E Лечение при передозировке - симптоматическое и поддерживающее. В случае передозировки рекомендуется прием жидкости внутрь с целью увеличения диуреза."},{"name":"Применение при беременности и кормлении грудью","value":"При беременности препарат назначают только тогда, когда потенциальная польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПри необходимости назначения препарата в период лактации следует прекратить грудное вскармливание на время лечения."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Специальных\tисследований не проводилось, но пациентов следует информировать о том, что применение препарата может вызвать головокружение. При появлении головокружения следует воздержаться от выполнения указанных видов деятельности."},{"name":"Особые указания","value":"Во время лечения фосфомицином могут возникнуть реакции гиперчувствительности, включая анафилаксию и анафилактический шок, представляющие опасность для жизни. Если такая реакция возникает, необходимо исключить повторный прием фосфомицина и провести адекватное лечение. \u003Cbr\u003EАнтибиотик-ассоциированная диарея была отмечена при использовании практически всех антибактериальных средств, в том числе фосфомицина. Ее тяжесть может варьироваться от легкой диареи до смертельного колита. Диарея, в особенности тяжелая, непрекращающаяся и/или с кровью, во время или после лечения препаратом Монурал (в том числе, в течение нескольких недель после лечения), может быть симптомом заболевания, вызванного Clostridium difficile (псевдомембранозный колит). Этот диагноз важно учитывать при лечении пациентов во время или после приема препарата Монурал. При предполагаемом или подтвержденном диагнозе псевдомембранозного колита соответствующее лечение должно быть начато незамедлительно. \u003Cbr\u003EПрепараты, подавляющие перистальтику кишечника, в данной клинической ситуации противопоказаны. Почечная недостаточность: концентрация фосфомицина в моче сохраняется в течение 48 часов после приема обычной дозы, если клиренс креатинина выше 10 мл/мин. Препарат противопоказан пациентам, проходящим гемодиализ. \u003Cbr\u003EПациентам сахарным диабетом следует учитывать, что в 1 пакете препарата Монурал с дозировкой 2 г или 3 г фосфомицина содержится 2,100 г или 2,213 г сахарозы, соответственно. Пациентам с редкими наследственными заболеваниями, такими как непереносимость фруктозы, мальабсорбция глюкозы-галактозы или недостаточность сахаразы-изомальтазы, данный препарат противопоказан."},{"name":"Взаимодействие","value":"При совместном применении с фосфомицином, метоклопрамид снижает концентрацию фосфомицина в сыворотке крови и моче. Одновременное применение антацидов или солей кальция приводит к уменьшению концентрации фосфомицина в плазме крови и моче. \u003Cbr\u003EДругие препараты, которые увеличивают двигательную активность желудочно- кишечного тракта, могут вызывать аналогичный эффект. Возможны специфические проблемы, связанные с изменением международного нормализованного отношения (МНО). \u003Cbr\u003EУ пациентов, получающих антибиотики, были зарегистрированы, многочисленные случаи повышенной активности антагонистов антивитамина К. К факторам риска относятся тяжелая инфекция или воспаление, возраст и плохое общее состояние здоровья. В этих условиях трудно определить, является ли изменение в МНО следствием инфекционного заболевания или его лечения. Тем не менее, определенные классы антибиотиков чаще упоминаются в этой связи, а именно: фторхинолоны, макролиды, циклины, ко- тримоксазол и некоторые цефалоспорины."},{"name":"Регистрационный номер","value":"П N012976/01"},{"name":"Дата государственной регистрации","value":"11.07.2007"},{"name":"Владелец регистрационного удостоверения","value":"Zambon"},{"name":"Изготовитель","value":"Zambon"},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Швейцария"},{"name":"Название препарата","value":"Монурал"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_13341611603642618428"}}}}
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Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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781 ₽

Скидка: 16%
–16 %
Вместо:929 ₽
  • Сегодня, самовывоз • 0 ₽
ЕАПТЕКА
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  • Фосфомицин-ЛекТ пор. д/приг. р-ра д/вн. приема пак., 3 г, 8 г, 1 шт.
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    Фосфомицин-ЛекТ пор. д/приг. р-ра д/вн. приема пак., 3 г, 8 г, 1 шт.

    Рейтинг товара: 4.7 из 5
    на основе 40 оценок
    Цена 339 ₽
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  • Экофомурал гран. д/приг. р-ра д/вн., 3 г, 8 г, 1 шт.
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    Экофомурал гран. д/приг. р-ра д/вн., 3 г, 8 г, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 557 ₽
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  • Уронормин-Ф пор. для приг. р-ра д/вн. приема, 3 г, 8 г, 1 шт.
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    Уронормин-Ф пор. для приг. р-ра д/вн. приема, 3 г, 8 г, 1 шт.

    Рейтинг товара: 4.8 из 5
    на основе 11 оценок
    Цена 613 ₽
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  • Овеа гран. д/приг. р-ра д/вн. приема пак., 3 г, 1 шт.
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    Овеа гран. д/приг. р-ра д/вн. приема пак., 3 г, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 790 ₽
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  • Фурамаг капс., 25 мг, 30 шт.
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    Фурамаг капс., 25 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 13 оценок
    Цена 1 271 ₽
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  • Амоксиклав таб. п/о плен., 875 мг+125 мг, 14 шт.
    –19 %
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    Амоксиклав таб. п/о плен., 875 мг+125 мг, 14 шт.

    Рейтинг товара: 5 из 5
    на основе 43 оценки
    Цена 500 ₽ вместо 620
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  • Амоксициллин капс., 500 мг, 16 шт.
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    Амоксициллин капс., 500 мг, 16 шт.

    Рейтинг товара: 4.9 из 5
    на основе 64 оценки
    Цена 115 ₽
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  • Фурагин таб., 50 мг, 30 шт.
    –10 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-42zq60d6bwc/toggleWishlist":{"skuId":"227814566","productId":1778176920,"offerId":"HkNnnirKccTj-A0yFvkeNQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxMHkw9bU85AsEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUImKfzzwYQptnQbBjX8c8GIPfcwQc=","sign":"eTyFjjUPO4I0WxL9jq5AXjakm6voFpbnXr2w84VwDnU="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-42zq60d6bwc/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Фурагин таб., 50 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 6 оценок
    Цена 362 ₽ вместо 402
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  • Азитромицин капс., 500 мг, 3 шт.
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    Азитромицин капс., 500 мг, 3 шт.

    Рейтинг товара: 4.7 из 5
    на основе 156 оценок
    Цена 96 ₽
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  • Ципрофлоксацин таб. п/о плен., 250 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gnsvwypat8c/toggleWishlist":{"skuId":"227814594","productId":1434054466,"offerId":"ZBd_bcnTOtVxIpRDG9r60g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxMHkw9bU85AsEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIwt7nqwUQwtnQbBjX8c8GIPfcwQc=","sign":"hTITJbo/DAmQnft5Opyk9OJAvdQZ+Xv7qo3wMQugoYU="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gnsvwypat8c/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ципрофлоксацин таб. п/о плен., 250 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 20 оценок
    Цена 44 ₽
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Инструкция

Показания к применению

Инфекционно-воспалительные заболевания, вызванные чувствительными к фосфомицину микроорганизмами:
- острый бактериальный цистит, острые приступы рецидивирующего бактериального цистита;
- бактериальный неспецифический уретрит;
- бессимптомная массивная бактериурия у беременных;
- послеоперационные инфекции мочевыводящих путей;
- профилактика инфекций при хирургическом вмешательстве на мочевыводящих путях и при трансуретральных диагностических исследованиях.

Противопоказания

- повышенная чувствительность к фосфомицину, другим компонентам препарата;
- тяжелая почечная недостаточность (клиренс креатинина <10 мл/мин), детский возраст до 12 лет (для дозировки 3 г);
- детский возраст до 5 лет (для дозировки 2 г);
- гемодиализ, дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция.

Способ применения и дозы

Внутрь.
Гранулы растворяют в 1/2 стакана воды (50 75 мл) или другого напитка, перемешивают до полного растворения, принимают сразу же после растворения. Монурал применяют один раз в сутки внутрь натощак за 1 час до или через 2-3 часа после еды, предпочтительно перед сном, предварительно опорожнив мочевой пузырь.
Взрослым и детям от 12 до 18 лет: по 1 пакету (3 г) 1 раз в день однократно.
С целью профилактики инфицирования мочевыводящих путей при хирургическом вмешательстве, трансуретральных диагностических процедурах Монурал принимают 2 раза по 3 г: за 3 часа до вмешательства и через 24 часа после вмешательства.
Детям от 5 лет до 12 лет: по 1 пакету (2 г) 1 раз в день однократно. С целью профилактики инфицирования мочевыводящих путей при хирургическом вмешательстве, трансуретральных диагностических процедурах Монурал принимают 2 раза по 2 г: за 3 часа до вмешательства и через 24 часа после вмешательства.
В более тяжелых случаях (пожилые пациенты, рецидивирующие инфекции) принимают еще 1 пакет через 24 часа.
У пациентов с легкой или средней степенью тяжести почечной недостаточности коррекция дозы не требуется. У пациентов с тяжелой почечной недостаточностью или находящихся на гемодиализе применение препарата противопоказано. У пациентов с печеночной недостаточностью коррекции дозы не требуется.
Полная инструкция
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Монурал гран. д/приг. р-ра д/вн. приема
Монурал гран. д/приг. р-ра д/вн. приема, 3 г, 3 г, 1 шт.
4.9
(40)
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9 вопросов
Инструкция

781 ₽

Скидка: 16%
–16 %
Вместо:929 ₽
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4.9
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У продавца:40 оценок·8 отзывов
У всех продавцов:349 оценок·109 отзывов
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user avatar
3 месяца назад • Светлана Максимкина • Куплен на Маркете
Достоинства: хорошее средство
Недостатки: нет
Комментарий: всё хорошо, сроки отличные
user avatar
5 месяцев назад • Светлана Кравцова • Куплен на Маркете
Достоинства: Действительно работает. Случилась проблема. Улетала рано утром в отпуск. Купила лекарство в аптеке в аэропорту. В течение часа проблема ушла.
user avatar
3 месяца назад • Татьяна Боброва • Куплен на Маркете
Достоинства: Помогает
Недостатки: Нет
Комментарий: При обострении цистита спасаюсь только им
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