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Моксонидин таб. п/о плен., 0.2 мг, 90 шт.

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4.7
(31)
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Дозировка: 0.2 мг

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Количество штук в упаковке, шт.: 90

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Коротко о товаре

Артикул Маркета
419787805
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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применению","value":"Артериальная гипертензия."},{"name":"Противопоказания","value":"-повышенная чувствительность к активному веществу и другим компонентам препарата;\u003Cbr\u003E-ангионевротический отёк в анамнезе;\u003Cbr\u003E-синдром слабости синусового узла или синоатриальная блокада;\u003Cbr\u003E-тяжёлая печеночная недостаточность;\u003Cbr\u003E-выраженная брадикардия (частота сердечных сокращений (ЧСС) покоя менее 50 уд./мин);\u003Cbr\u003E-атриовентрикулярная блокада II или III степени;\u003Cbr\u003E-острая и хроническая сердечная недостаточность;\u003Cbr\u003E-период грудного вскармливания;\u003Cbr\u003Eнаследственная непереносимость галактозы, дефицит лактазы или мальабсорбция глюкозы-галактозы;\u003Cbr\u003E-возраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности)."},{"name":"Состав","value":"1 таблетка 0,2 мг, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EДействующее вещество: моксонидин 0,2 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат, целлюлоза микрокристаллическая (тип 102), повидон-К25, кросповидон, магния стеарат;\u003Cbr\u003EСостав оболочки: гипромеллоза, титана диоксид, макрогол 400, диметикон 100.\u003Cbr\u003E1 таблетка 0,3 мг, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EДействующее вещество: моксонидин 0,3 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат, целлюлоза микрокристаллическая (тип 102), повидон-К25, кросповидон, магния стеарат;\u003Cbr\u003EСостав оболочки: гипромеллоза, титана диоксид, макрогол 400, диметикон 100, краситель железа оксид желтый.\u003Cbr\u003E1 таблетка 0,4 мг, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EДействующее вещество: моксонидин 0,4 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат, целлюлоза микрокристаллическая (тип 102), повидон-К25, кросповидон, магния стеарат;\u003Cbr\u003EСостав оболочки: гипромеллоза, титана диоксид, макрогол 400, диметикон 100."},{"name":"Действующее вещество","value":"Моксонидин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28709517"]}}},{"name":"Способ применения и дозы","value":"Внутрь, независимо от приема пищи.\u003Cbr\u003EВ большинстве случаев начальная доза препарата Моксонидин составляет 0,2 мг в сутки. Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии. Коррекция дозы для пациентов с печеночной недостаточностью не требуется.\u003Cbr\u003EНачальная доза для пациентов, находящихся на гемодиализе - 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг в сутки.\u003Cbr\u003EПациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин)."},{"name":"Побочные действия","value":"Наиболее частые побочные эффекты у пациентов, принимающих моксонидин: сухость во рту, головокружение, астения и сонливость. Эти симптомы часто уменьшаются по прошествии первых недель терапии.\u003Cbr\u003EУ пациентов, принимавших участие в плацебо-контролируемых клинических исследованиях препарата МОКСОНИДИН, отмечены следующие побочные эффекты. Частота побочных эффектов, приведенных ниже, определялась соответственно следующему: очень часто (\u003E1/10); часто (\u003E1/100, \u003C1/10); нечасто (\u003E1/1000, \u003C1/100); включая отдельные сообщения.\u003Cbr\u003EСо стороны центральной нервной системы:\u003Cbr\u003Eчасто - головная боль*, головокружение (вертиго), сонливость, бессонница;\u003Cbr\u003Eнечасто - обморок*, повышенная возбудимость.\u003Cbr\u003EСо стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто - выраженное снижение АД, ортостатическая гипотензия*, брадикардия.\u003Cbr\u003EСо стороны желудочно-кишечного тракта:\u003Cbr\u003Eочень часто - сухость во рту;\u003Cbr\u003Eчасто - диарея, тошнота, рвота, диспепсия.\u003Cbr\u003EСо стороны кожи и подкожных тканей:\u003Cbr\u003Eчасто - кожная сыпь, зуд;\u003Cbr\u003Eнечасто - ангионевротический отек.\u003Cbr\u003EСо стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eнечасто - звон в ушах.\u003Cbr\u003EСо стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eчасто - боль в спине;\u003Cbr\u003Eнечасто - боль в области шеи.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eчасто - астения;\u003Cbr\u003Eнечасто - периферические отеки.\u003Cbr\u003E(* - частота сопоставима с плацебо)."},{"name":"Фармакологическое действие","value":"Моксонидин является гипотензивным средством с центральным механизмом действия. В стволовых структурах мозга (ростральный слой боковых желудочков) моксонидин селективно стимулирует имидазолин-чувствительные рецепторы, принимающие участие в тонической и рефлекторной регуляции симпатической нервной системы. Стимуляция имидазолиновых рецепторов снижает периферическую симпатическую активность и артериальное давление (АД).\u003Cbr\u003EМоксонидин отличается от других симпатолитических гипотензивных средств более низким сродством к α2-адренорецепторам, что объясняет меньшую вероятность развития седативного эффекта и сухости во рту.\u003Cbr\u003EПрием моксонидина приводит к снижению системного сосудистого сопротивления и АД. Гипотензивный эффект моксонидина подтвержден в двойных слепых плацебо-контролируемых рандомизированных исследованиях.\u003Cbr\u003EРезультаты клинического исследования с участием 42 пациентов с артериальной гипертензией и гипертрофией левого желудочка (ГЛЖ) продемонстрировали, что при сходном снижении АД, применение комбинации антагонистов рецепторов к ангиотензину II с моксонидином позволяет в большей степени уменьшить ГЛЖ по сравнению со свободной комбинацией тиазидного диуретика и блокатора кальциевых каналов (15 % против 11 %; р \u003C 0,05).\u003Cbr\u003EМоксонидин улучшает на 21 % индекс чувствительности к инсулину (в сравнении с плацебо) у пациентов с ожирением, инсулинорезистентностью и умеренной степенью артериальной гипертензии."},{"name":"Фармакологическая группа","value":"гипотензивное средство центрального действия"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25°С."},{"name":"Передозировка","value":"Имеются сообщения о нескольких случаях передозировки без летального исхода, когда одномоментно применялись дозы до 19,6 мг.\u003Cbr\u003EСимптомы: головная боль, седативный эффект, сонливость, выраженное снижение АД, головокружение, астения, брадикардия, сухость во рту, рвота, усталость, боль в эпигастральной области, угнетение дыхания и нарушение сознания.\u003Cbr\u003EКроме того, возможно также кратковременное повышение АД, тахикардия и гипергликемия, как было показано в нескольких исследованиях по изучению высоких доз на животных.\u003Cbr\u003EЛечение: специфического антидота не существует. В случае выраженного снижения АД может потребоваться восстановление объема циркулирующей крови за счет введения жидкости и допамина (инъекционно).\u003Cbr\u003EБрадикардия может быть купирована атропином (инъекционное введение).\u003Cbr\u003EВ тяжелых случаях передозировки рекомендуется тщательно контролировать нарушения сознания и не допускать угнетения дыхания.\u003Cbr\u003EАнтагонисты α-адренорецепторов могут уменьшать или устранять парадоксальные гипертензивные эффекты при передозировке моксонидином."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EКлинические данные о применении у беременных отсутствуют.\u003Cbr\u003EВ ходе исследований на животных было установлено эмбриотоксическое действие препарата.\u003Cbr\u003EМоксонидин следует назначать беременным только после тщательной оценки соотношения риска и пользы, когда польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EМоксонидин проникает в грудное молоко и поэтому не должен назначаться во время кормления грудью.\u003Cbr\u003EПри необходимости применения лекарственного препарата Моксонидин в период лактации, грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследования влияния препарата на способность управлять автомобилем и другими механизмами не проводились.\u003Cbr\u003EИмеются сообщения о сонливости и головокружении в период лечения моксонидином. Это следует учитывать при выполнении вышеуказанных действий."},{"name":"Особые указания","value":"Во время лечения необходим регулярный контроль АД.\u003Cbr\u003EВ постмаркетинговом наблюдении зафиксированы случаи атриовентрикулярной блокады различной степени тяжести у пациентов, принимающих моксонидин. Связь между приемом препарата Моксонидин и замедлением атриовентрикулярной проводимости не может быть полностью исключена. Таким образом, при лечении пациентов с вероятной предрасположенностью к развитию атриовентрикулярной блокады рекомендуется соблюдать осторожность.\u003Cbr\u003EПри необходимости отмены одновременно принимаемых β-адреноблокаторов и препарата МОКСОНИДИН, сначала отменяют бета-адреноблокаторы и лишь через несколько дней препарат МОКСОНИДИН.\u003Cbr\u003EВ настоящее время нет подтверждений того, что прекращение приема моксонидина приводит к повышению АД.\u003Cbr\u003EОднако не рекомендуется прекращать прием препарата Моксонидин резко, вместо этого следует постепенно уменьшать дозу препарата в течение двух недель.\u003Cbr\u003EУ пациентов пожилого возраста может быть повышен риск развития сердечно-сосудистых осложнений вследствие применения гипотензивных препаратов, поэтому терапию препаратом Моксонидин следует начинать с минимальной дозы.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EАтриовентрикулярная блокада I степени (риск развития брадикардии), заболевания коронарных артерий (в т.ч. ишемическая болезнь сердца, нестабильная стенокардия, ранний постинфарктный период), заболевания периферического кровообращения (в т.ч. перемежающаяся хромота, синдром Рейно), эпилепсия, болезнь Паркинсона, депрессия, глаукома, умеренная почечная недостаточность (КК 30-60 мл/мин, креатинин сыворотки 105-160 мкмоль/л), печеночная недостаточность, беременность."},{"name":"Взаимодействие","value":"Совместное применение моксонидина с другими гипотензивными средствами приводит к аддитивному эффекту.\u003Cbr\u003EТрициклические антидепрессанты могут снижать эффективность гипотензивных средств центрального действия, в связи с чем не рекомендуется их прием совместно с моксонидином.\u003Cbr\u003EМоксонидин может усиливать седативное действие трициклических антидепрессантов (необходимо избегать совместного назначения), транквилизаторов, этанола, седативных и снотворных средств.\u003Cbr\u003EМоксонидин способен умеренно улучшать ослабленные когнитивные функции у пациентов, получающих лоразепам.\u003Cbr\u003EМоксонидин может усиливать седативный эффект производных бензодиазепина при их одновременном назначении.\u003Cbr\u003EМоксонидин выделяется путем канальцевой секреции. Поэтому не исключено его взаимодействие с другими препаратами, выделяющимися путем канальцевой секреции."},{"name":"Регистрационный номер","value":"ЛП-008182"},{"name":"Дата государственной регистрации","value":"20.05.2022"},{"name":"Владелец регистрационного удостоверения","value":"ПРАНАФАРМ","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:12507927"]}}},{"name":"Изготовитель","value":"ПРАНАФАРМ"},{"name":"Страна-производитель","value":"Россия"},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"13392448498281280988":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Назначение","value":"артериальная гипертензия"},{"name":"Показания к применению","value":"Артериальная гипертензия."},{"name":"Противопоказания","value":"-повышенная чувствительность к активному веществу и другим компонентам препарата;\u003Cbr\u003E-ангионевротический отёк в анамнезе;\u003Cbr\u003E-синдром слабости синусового узла или синоатриальная блокада;\u003Cbr\u003E-тяжёлая печеночная недостаточность;\u003Cbr\u003E-выраженная брадикардия (частота сердечных сокращений (ЧСС) покоя менее 50 уд./мин);\u003Cbr\u003E-атриовентрикулярная блокада II или III степени;\u003Cbr\u003E-острая и хроническая сердечная недостаточность;\u003Cbr\u003E-период грудного вскармливания;\u003Cbr\u003Eнаследственная непереносимость галактозы, дефицит лактазы или мальабсорбция глюкозы-галактозы;\u003Cbr\u003E-возраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности)."},{"name":"Состав","value":"1 таблетка 0,2 мг, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EДействующее вещество: моксонидин 0,2 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат, целлюлоза микрокристаллическая (тип 102), повидон-К25, кросповидон, магния стеарат;\u003Cbr\u003EСостав оболочки: гипромеллоза, титана диоксид, макрогол 400, диметикон 100.\u003Cbr\u003E1 таблетка 0,3 мг, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EДействующее вещество: моксонидин 0,3 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат, целлюлоза микрокристаллическая (тип 102), повидон-К25, кросповидон, магния стеарат;\u003Cbr\u003EСостав оболочки: гипромеллоза, титана диоксид, макрогол 400, диметикон 100, краситель железа оксид желтый.\u003Cbr\u003E1 таблетка 0,4 мг, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EДействующее вещество: моксонидин 0,4 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат, целлюлоза микрокристаллическая (тип 102), повидон-К25, кросповидон, магния стеарат;\u003Cbr\u003EСостав оболочки: гипромеллоза, титана диоксид, макрогол 400, диметикон 100."},{"name":"Действующее вещество","value":"Моксонидин"},{"name":"Способ применения и дозы","value":"Внутрь, независимо от приема пищи.\u003Cbr\u003EВ большинстве случаев начальная доза препарата Моксонидин составляет 0,2 мг в сутки. Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии. Коррекция дозы для пациентов с печеночной недостаточностью не требуется.\u003Cbr\u003EНачальная доза для пациентов, находящихся на гемодиализе - 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг в сутки.\u003Cbr\u003EПациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин)."},{"name":"Побочные действия","value":"Наиболее частые побочные эффекты у пациентов, принимающих моксонидин: сухость во рту, головокружение, астения и сонливость. Эти симптомы часто уменьшаются по прошествии первых недель терапии.\u003Cbr\u003EУ пациентов, принимавших участие в плацебо-контролируемых клинических исследованиях препарата МОКСОНИДИН, отмечены следующие побочные эффекты. Частота побочных эффектов, приведенных ниже, определялась соответственно следующему: очень часто (\u003E1/10); часто (\u003E1/100, \u003C1/10); нечасто (\u003E1/1000, \u003C1/100); включая отдельные сообщения.\u003Cbr\u003EСо стороны центральной нервной системы:\u003Cbr\u003Eчасто - головная боль*, головокружение (вертиго), сонливость, бессонница;\u003Cbr\u003Eнечасто - обморок*, повышенная возбудимость.\u003Cbr\u003EСо стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто - выраженное снижение АД, ортостатическая гипотензия*, брадикардия.\u003Cbr\u003EСо стороны желудочно-кишечного тракта:\u003Cbr\u003Eочень часто - сухость во рту;\u003Cbr\u003Eчасто - диарея, тошнота, рвота, диспепсия.\u003Cbr\u003EСо стороны кожи и подкожных тканей:\u003Cbr\u003Eчасто - кожная сыпь, зуд;\u003Cbr\u003Eнечасто - ангионевротический отек.\u003Cbr\u003EСо стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eнечасто - звон в ушах.\u003Cbr\u003EСо стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eчасто - боль в спине;\u003Cbr\u003Eнечасто - боль в области шеи.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eчасто - астения;\u003Cbr\u003Eнечасто - периферические отеки.\u003Cbr\u003E(* - частота сопоставима с плацебо)."},{"name":"Фармакологическое действие","value":"Моксонидин является гипотензивным средством с центральным механизмом действия. В стволовых структурах мозга (ростральный слой боковых желудочков) моксонидин селективно стимулирует имидазолин-чувствительные рецепторы, принимающие участие в тонической и рефлекторной регуляции симпатической нервной системы. Стимуляция имидазолиновых рецепторов снижает периферическую симпатическую активность и артериальное давление (АД).\u003Cbr\u003EМоксонидин отличается от других симпатолитических гипотензивных средств более низким сродством к α2-адренорецепторам, что объясняет меньшую вероятность развития седативного эффекта и сухости во рту.\u003Cbr\u003EПрием моксонидина приводит к снижению системного сосудистого сопротивления и АД. Гипотензивный эффект моксонидина подтвержден в двойных слепых плацебо-контролируемых рандомизированных исследованиях.\u003Cbr\u003EРезультаты клинического исследования с участием 42 пациентов с артериальной гипертензией и гипертрофией левого желудочка (ГЛЖ) продемонстрировали, что при сходном снижении АД, применение комбинации антагонистов рецепторов к ангиотензину II с моксонидином позволяет в большей степени уменьшить ГЛЖ по сравнению со свободной комбинацией тиазидного диуретика и блокатора кальциевых каналов (15 % против 11 %; р \u003C 0,05).\u003Cbr\u003EМоксонидин улучшает на 21 % индекс чувствительности к инсулину (в сравнении с плацебо) у пациентов с ожирением, инсулинорезистентностью и умеренной степенью артериальной гипертензии."},{"name":"Фармакологическая группа","value":"гипотензивное средство центрального действия"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25°С."},{"name":"Передозировка","value":"Имеются сообщения о нескольких случаях передозировки без летального исхода, когда одномоментно применялись дозы до 19,6 мг.\u003Cbr\u003EСимптомы: головная боль, седативный эффект, сонливость, выраженное снижение АД, головокружение, астения, брадикардия, сухость во рту, рвота, усталость, боль в эпигастральной области, угнетение дыхания и нарушение сознания.\u003Cbr\u003EКроме того, возможно также кратковременное повышение АД, тахикардия и гипергликемия, как было показано в нескольких исследованиях по изучению высоких доз на животных.\u003Cbr\u003EЛечение: специфического антидота не существует. В случае выраженного снижения АД может потребоваться восстановление объема циркулирующей крови за счет введения жидкости и допамина (инъекционно).\u003Cbr\u003EБрадикардия может быть купирована атропином (инъекционное введение).\u003Cbr\u003EВ тяжелых случаях передозировки рекомендуется тщательно контролировать нарушения сознания и не допускать угнетения дыхания.\u003Cbr\u003EАнтагонисты α-адренорецепторов могут уменьшать или устранять парадоксальные гипертензивные эффекты при передозировке моксонидином."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EКлинические данные о применении у беременных отсутствуют.\u003Cbr\u003EВ ходе исследований на животных было установлено эмбриотоксическое действие препарата.\u003Cbr\u003EМоксонидин следует назначать беременным только после тщательной оценки соотношения риска и пользы, когда польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EМоксонидин проникает в грудное молоко и поэтому не должен назначаться во время кормления грудью.\u003Cbr\u003EПри необходимости применения лекарственного препарата Моксонидин в период лактации, грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследования влияния препарата на способность управлять автомобилем и другими механизмами не проводились.\u003Cbr\u003EИмеются сообщения о сонливости и головокружении в период лечения моксонидином. Это следует учитывать при выполнении вышеуказанных действий."},{"name":"Особые указания","value":"Во время лечения необходим регулярный контроль АД.\u003Cbr\u003EВ постмаркетинговом наблюдении зафиксированы случаи атриовентрикулярной блокады различной степени тяжести у пациентов, принимающих моксонидин. Связь между приемом препарата Моксонидин и замедлением атриовентрикулярной проводимости не может быть полностью исключена. Таким образом, при лечении пациентов с вероятной предрасположенностью к развитию атриовентрикулярной блокады рекомендуется соблюдать осторожность.\u003Cbr\u003EПри необходимости отмены одновременно принимаемых β-адреноблокаторов и препарата МОКСОНИДИН, сначала отменяют бета-адреноблокаторы и лишь через несколько дней препарат МОКСОНИДИН.\u003Cbr\u003EВ настоящее время нет подтверждений того, что прекращение приема моксонидина приводит к повышению АД.\u003Cbr\u003EОднако не рекомендуется прекращать прием препарата Моксонидин резко, вместо этого следует постепенно уменьшать дозу препарата в течение двух недель.\u003Cbr\u003EУ пациентов пожилого возраста может быть повышен риск развития сердечно-сосудистых осложнений вследствие применения гипотензивных препаратов, поэтому терапию препаратом Моксонидин следует начинать с минимальной дозы.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EАтриовентрикулярная блокада I степени (риск развития брадикардии), заболевания коронарных артерий (в т.ч. ишемическая болезнь сердца, нестабильная стенокардия, ранний постинфарктный период), заболевания периферического кровообращения (в т.ч. перемежающаяся хромота, синдром Рейно), эпилепсия, болезнь Паркинсона, депрессия, глаукома, умеренная почечная недостаточность (КК 30-60 мл/мин, креатинин сыворотки 105-160 мкмоль/л), печеночная недостаточность, беременность."},{"name":"Взаимодействие","value":"Совместное применение моксонидина с другими гипотензивными средствами приводит к аддитивному эффекту.\u003Cbr\u003EТрициклические антидепрессанты могут снижать эффективность гипотензивных средств центрального действия, в связи с чем не рекомендуется их прием совместно с моксонидином.\u003Cbr\u003EМоксонидин может усиливать седативное действие трициклических антидепрессантов (необходимо избегать совместного назначения), транквилизаторов, этанола, седативных и снотворных средств.\u003Cbr\u003EМоксонидин способен умеренно улучшать ослабленные когнитивные функции у пациентов, получающих лоразепам.\u003Cbr\u003EМоксонидин может усиливать седативный эффект производных бензодиазепина при их одновременном назначении.\u003Cbr\u003EМоксонидин выделяется путем канальцевой секреции. Поэтому не исключено его взаимодействие с другими препаратами, выделяющимися путем канальцевой секреции."},{"name":"Регистрационный номер","value":"ЛП-008182"},{"name":"Дата государственной регистрации","value":"20.05.2022"},{"name":"Владелец регистрационного удостоверения","value":"ПРАНАФАРМ"},{"name":"Изготовитель","value":"ПРАНАФАРМ"},{"name":"Страна-производитель","value":"Россия"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_1164211077414802097"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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410 ₽

Скидка: 11%
–11 %
Вместо:460 ₽
  • 11-13 июня, самовывоз • 0 ₽
POLZAru
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  • Моксонидин Канон таб. п/о плен., 0.4 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-nkyrecaf1k/toggleWishlist":{"skuId":"186557801","productId":1401075448,"offerId":"Su2mRI_bKvYwvVzuGwMvVg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzp2XlIHOxeJ8EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI+O2KnAUQ6cr6WBjOwtkHINfcwQc=","sign":"hAzbjn2P6N51n4JjwIjRkJpNi8oRUpJkWRoxQLC921E="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-nkyrecaf1k/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин Канон таб. п/о плен., 0.4 мг, 28 шт.

    Рейтинг товара: 4.7 из 5
    на основе 23 оценки
    Цена 216 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-nkyrecaf1k/addToCartButton":{"offerId":"Su2mRI_bKvYwvVzuGwMvVg","skuId":"186557801","pendingCartItem":{"productId":1401075448,"offerId":"Su2mRI_bKvYwvVzuGwMvVg","showPlaceId":"OTNDnItfwRMjN9MRHuEMMiX2G0qePTzBZw6igD2oGEsjTpwRcCysMbpAGvBXa1Vdn_h0t3-3SEo4zzIgA77uk5gwrBcS8xyLvDafzZ3YQqAaUSmOm1bY7Smth3bxJqBiyz1HszJeCMZtNcGdwmGjDhyOj0uehGiJrCSI0JpG93Ca6BpAsqcy6Oiab1CYUi3hHnCFOLwYykxBuMt-8Dlw4A,,","feeShow":"OTNDnItfwRMjN9MRHuEMMiX2G0qePTzBZw6igD2oGEsjTpwRcCysMbpAGvBXa1Vdn_h0t3-3SEo4zzIgA77uk5gwrBcS8xyLvDafzZ3YQqAaUSmOm1bY7Smth3bxJqBiyz1HszJeCMZtNcGdwmGjDhyOj0uehGiJrCSI0JpG93Ca6BpAsqcy6Oiab1CYUi3hHnCFOLwYykxBuMt-8Dlw4A,,","skuId":"186557801","shopId":77075781,"price":{"applicablePriceDiscounts":[],"value":"216","currency":"RUR"},"hid":"15756887","name":"Моксонидин Канон таб. п/о плен., 0.4 мг, 28 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  • Моксонидин Реневал таб. п/о плен., 0.2 мг, 90 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-v36vz2vz489/toggleWishlist":{"skuId":"101770901161","productId":1754820958,"offerId":"d6KCtYQlLJoMIYG_0bgXFQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzp2XlIHOxeJ8EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI3uLhxAYQqe2SkPsCGPKsgggg19zBBw==","sign":"4vFrJ0SnzKiNP3ivsvMfiTFh2YFPuq3yyL2ctN5Z+6I="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-v36vz2vz489/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин Реневал таб. п/о плен., 0.2 мг, 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 21 оценка
    Цена 375 ₽
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  • Моксонидин таб. п/о плен., 0.2 мг, 14 шт.
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    Моксонидин таб. п/о плен., 0.2 мг, 14 шт.

    Рейтинг товара: 5 из 5
    на основе 30 оценок
    Цена 148 ₽
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  • Моксонидин-АЛСИ таб. п/о плен., 0.2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o0ei4q8laue/toggleWishlist":{"skuId":"101474629555","productId":1460168636,"offerId":"YsfCv0uxuqmEj4FmXIZzIA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzp2XlIHOxeJ8EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIvM+huAUQs+/vgvoCGMfc0Acg19zBBw==","sign":"GtZhMm4ZPq/fhuDLiBUyYGqozneNzAehGeUD+bl5+o8="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o0ei4q8laue/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин-АЛСИ таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 8 оценок
    Цена 177 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o0ei4q8laue/addToCartButton":{"offerId":"YsfCv0uxuqmEj4FmXIZzIA","skuId":"101474629555","pendingCartItem":{"productId":1460168636,"offerId":"YsfCv0uxuqmEj4FmXIZzIA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMiX2G0qePTzBJFI_-amcw71FcDGw_pbpNTVekZvGK90CC8sC4d196Kf9LnH32ANBPlRflo8hZRXVuCaouyL76A2HLUhIr4PKC-vqcWCKnMDjRlcl3jQI_KGZPrFWu3XuUQwcbmL58Cj14Y8YC3PQmImqictK6Ef8tyNQSzbKO5GIB5LaKc1VCEA-oP7OZw26QQ,,","feeShow":"OTNDnItfwRMjN9MRHuEMMiX2G0qePTzBJFI_-amcw71FcDGw_pbpNTVekZvGK90CC8sC4d196Kf9LnH32ANBPlRflo8hZRXVuCaouyL76A2HLUhIr4PKC-vqcWCKnMDjRlcl3jQI_KGZPrFWu3XuUQwcbmL58Cj14Y8YC3PQmImqictK6Ef8tyNQSzbKO5GIB5LaKc1VCEA-oP7OZw26QQ,,","skuId":"101474629555","shopId":77075781,"price":{"applicablePriceDiscounts":[],"value":"177","currency":"RUR"},"hid":"15756887","name":"Моксонидин-АЛСИ таб. п/о плен., 0.2 мг, 30 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  • Моксонидин таб. п/о плен., 400 мкг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zajyu96mj4d/toggleWishlist":{"skuId":"228057931","productId":1401075705,"offerId":"PXRRW-7Ez5XzISPl4f_KCw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzp2XlIHOxeJ8EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI+e+KnAUQy8bfbBir3tAHINfcwQc=","sign":"hVXE9aIF63gMWDX7vgopZ25EzI8EwC0AiTiqQFicmRA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zajyu96mj4d/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин таб. п/о плен., 400 мкг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 7 оценок
    Цена 289 ₽
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  • Моксонитекс таб. п/о плен., 0.2 мг, 28 шт.
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    Моксонитекс таб. п/о плен., 0.2 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 319 ₽
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  • Моксонидин-Алиум таб. п/о плен., 200 мкг, 14 шт., 1
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cv4pc1z7qn/toggleWishlist":{"skuId":"102438079754","productId":1755061555,"offerId":"OcyQizIF7vjxOpbQ6GpTQw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzp2XlIHOxeJ8EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIs7rwxAYQipqkzv0CGLGLuggg19zBBw==","sign":"4A3LvsfkSc7fzlTzwrBt4dd+dKpupVgxy4H6p45UGQY="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cv4pc1z7qn/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин-Алиум таб. п/о плен., 200 мкг, 14 шт., 1

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 89 ₽
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  • Моксонидин-Акрихин таб. п/о плен., 0.2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xiz5fcgx9o/toggleWishlist":{"skuId":"834997635","productId":1401075967,"offerId":"YCynmt7uRtWY2jjYa8AlDg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzp2XlIHOxeJ8EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI//GKnAUQg5uUjgMYntShBSDX3MEH","sign":"NwkGc6SSdqke2QO/ClHUBs1JbM3/aX/k9Rs8T/ob/wE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xiz5fcgx9o/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Моксонидин-Акрихин таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 6 оценок
    Цена 249 ₽
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  • Моксонидин Авексима таб. п/о плен., 0.2 мг, 30 шт.
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    Моксонидин Авексима таб. п/о плен., 0.2 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 7 оценок
    Цена 281 ₽
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  • Моксонидин солофарм таб. п/о плен., 0.2 мг, 30 шт.
    –19 %
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    Моксонидин солофарм таб. п/о плен., 0.2 мг, 30 шт.

    Цена 214 ₽ вместо 264
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Инструкция

Показания к применению

Артериальная гипертензия.

Противопоказания

-повышенная чувствительность к активному веществу и другим компонентам препарата;
-ангионевротический отёк в анамнезе;
-синдром слабости синусового узла или синоатриальная блокада;
-тяжёлая печеночная недостаточность;
-выраженная брадикардия (частота сердечных сокращений (ЧСС) покоя менее 50 уд./мин);
-атриовентрикулярная блокада II или III степени;
-острая и хроническая сердечная недостаточность;
-период грудного вскармливания;
наследственная непереносимость галактозы, дефицит лактазы или мальабсорбция глюкозы-галактозы;
-возраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности).

Способ применения и дозы

Внутрь, независимо от приема пищи.
В большинстве случаев начальная доза препарата Моксонидин составляет 0,2 мг в сутки. Максимальная разовая доза составляет 0,4 мг. Максимальная суточная доза, которую следует разделить на 2 приема, составляет 0,6 мг. Необходима индивидуальная коррекция суточной дозы в зависимости от переносимости пациентом проводимой терапии. Коррекция дозы для пациентов с печеночной недостаточностью не требуется.
Начальная доза для пациентов, находящихся на гемодиализе - 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза может быть увеличена до максимальной 0,4 мг в сутки.
Пациентам с почечной недостаточностью рекомендуется осторожный подбор дозы, особенно в начале лечения. Начальная доза должна составлять 0,2 мг в сутки. В случае необходимости и при хорошей переносимости суточная доза препарата может быть увеличена максимум до 0,4 мг для пациентов с умеренной почечной недостаточностью (КК более 30 мл/мин, но менее 60 мл/мин) и 0,3 мг для пациентов с тяжелой почечной недостаточностью (КК менее 30 мл/мин).
Полная инструкция
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Моксонидин таб. п/о плен.
Моксонидин таб. п/о плен., 0.2 мг, 90 шт.
4.7
(31)
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1 вопрос
Инструкция

410 ₽

Скидка: 11%
–11 %
Вместо:460 ₽
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4.7
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У продавца:31 оценка·8 отзывов
У всех продавцов:57 оценок·15 отзывов
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user avatar
4 дня назад • Алексей • Куплен на Маркете
Достоинства: помогает сразу и очень быстро
Недостатки: нет
Комментарий: Принимаю периодически,так как сильно сбивает давление и надо быть осторожнее
user avatar
9 месяцев назад • Анжелика А. • Куплен на Маркете
Достоинства: Покупаю уже не один раз. Помогают лечить высокой давление. Снизилось. Побочных эффектов не наблюдаю.
Недостатки: Нет
user avatar
2 месяца назад • Борис Мальцев • Куплен на Маркете
Достоинства: работает, давление приходит в норму
Недостатки: не выявлено
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