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Описание

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Тримектал ОД таб. пролонг. действ. п/о плен., 80 мг, 60 шт.

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У продавца: 
нет • На Маркете: 5.0
(12)
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Количество штук в упаковке, шт.: 60

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Коротко о товаре

Артикул Маркета
4453134792
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Прием препарата следует прекратить, если за это время улучшения не наступило. Продолжительность лечения определяется врачом. \u003Cbr/\u003EПациенты пожилого возраста\u003Cbr/\u003EУ пациентов старше 75 лет может наблюдаться повышенная экспозиция триметазидина из-за возрастного снижения функции почек, У пациентов с почечной недостаточностью умеренной степени тяжести (КК 30-60 мл/мин), рекомендуется снижение дозы, т.е. 1 таблетка, содержащая 35 мг триметазидина в день. Подбор дозы у пациентов старше 75 лет должен происходить с осторожностью. \u003Cbr/\u003EПациенты с нарушением функции почек\u003Cbr/\u003EУ пациентов с почечной недостаточностью умеренной степени тяжести (КК 30-60 мл/мин) рекомендуется снижение дозы, т.е. 1 таблетка, содержащая 35 мг триметазидина в день. \u003Cbr/\u003EПациенты с нарушением функции печени\u003Cbr/\u003EСледует проявлять осторожность при лечении пациентов с печеночной недостаточностью тяжелой степени тяжести ввиду того, что имеющиеся данные ограничены и не позволяют полностью исключить отсутствие влияния нарушений функции печени на метаболизм триметазидина. \u003Cbr/\u003EПациенты детского возраста\u003Cbr/\u003EБезопасность и эффективность применения триметазидина у пациентов младше 18 лет не установлены. Данные отсутствуют."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной организации здравоохранения (ВОЗ): \u003Cbr/\u003EОчень часто ≥ 1/10; \u003Cbr/\u003EЧасто от ≥ 1/100 до \u003C 1/10; \u003Cbr/\u003EНечасто от ≥ 1/1000 до \u003C 1/100; \u003Cbr/\u003EРедко от ≥ 1/10000 до \u003C 1/1000; \u003Cbr/\u003EОчень редко \u003C 1/10000, включая отдельные сообщения; \u003Cbr/\u003Eчастота неизвестна - по имеющимся данным установить частоту возникновения не представляется возможным. \u003Cbr/\u003EНарушения со стороны крови и лимфатической систем: \u003Cbr/\u003Eчастота неизвестна - агранулоцитоз, тромбоцитопения, тромбоцитопеническая пурпура. \u003Cbr/\u003EНарушения со стороны нервной системы: \u003Cbr/\u003Eчасто - головокружение, головная боль; \u003Cbr/\u003Eчастота неизвестна - симптомы паркинсонизма (тремор, акинезия, повышение тонуса), «шаткость» походки, синдром «беспокойных ног», другие связанные с ними двигательные нарушения, обычно обратимые после прекращения терапии. Нарушения сна (бессонница, сонливость). \u003Cbr/\u003EНарушения со стороны органа слуха и лабиринта: \u003Cbr/\u003Eчастота неизвестна - вертиго. \u003Cbr/\u003EНарушения со стороны сердца: \u003Cbr/\u003Eредко - ощущение сердцебиения, экстрасистолия, тахикардия. \u003Cbr/\u003EНарушения со стороны сосудов: \u003Cbr/\u003Eредко - артериальная гипотензия, ортостатическая гипотензия, которая может сопровождаться общей слабостью, головокружением или потерей равновесия, особенно при одновременном приеме гипотензивных препаратов, «приливы» крови к коже лица. \u003Cbr/\u003EЖелудочно-кишечные нарушения: \u003Cbr/\u003Eчасто - боль в животе, диарея, диспепсия, тошнота, рвота; частота неизвестна - запор. \u003Cbr/\u003EНарушения со стороны печени и желчевыводящих путей: \u003Cbr/\u003Eчастота неизвестна - гепатит. \u003Cbr/\u003EНарушения со стороны кожи и подкожной клетчатки: \u003Cbr/\u003Eчасто - кожная сыпь, зуд, крапивница; \u003Cbr/\u003Eчастота неизвестна - острый генерализованный экзантематозный пустулез, отек Квинке. \u003Cbr/\u003EОбщие нарушения и реакции в месте введения:\u003Cbr/\u003Eчасто - астения."},{"name":"Фармакологическое действие","value":"Механизм действия\u003Cbr/\u003EТриметазидин предотвращает снижение внутриклеточной концентрации аденозинтрифосфата (АТФ) путем сохранения энергетического метаболизма клеток в состоянии гипоксии. Таким образом, триметазидин обеспечивает нормальное функционирование мембранных ионных каналов, трансмембранный перенос ионов калия и натрия и сохранение клеточного гомеостаза. \u003Cbr/\u003EТриметазидин ингибирует окисление жирных кислот за счет селективного ингибирования фермента 3-кетоацил-КоА-тиолазы (3-КАТ) митохондриальной длинноцепочечной изоформы жирных кислот, что приводит к усилению окисления глюкозы и ускорению гликолиза с окислением глюкозы, что и обусловливает защиту миокарда от ишемии. Переключение энергетического метаболизма с окисления жирных кислот на окисление глюкозы лежит в основе фармакологических свойств триметазидина. \u003Cbr/\u003EФармакодинамические свойства: \u003Cbr/\u003E- поддерживает энергетический метаболизм сердца и нейросенсорных тканей во время ишемии; \u003Cbr/\u003E- уменьшает выраженность внутриклеточного ацидоза и изменений трансмембранного ионного потока, возникающих при ишемии; \u003Cbr/\u003E- понижает уровень миграции и инфильтрации полинуклеарных нейтрофилов в ишемизированных и реперфузированных тканях сердца; \u003Cbr/\u003E- уменьшает размер повреждения миокарда; \u003Cbr/\u003E- не оказывает прямого воздействия на показатели гемодинамики. \u003Cbr/\u003EУ пациентов со стенокардией триметазидин: \u003Cbr/\u003E- увеличивает коронарный резерв, тем самым замедляя наступление ишемии, вызванной физической нагрузкой, начиная с 15-го дня терапии; \u003Cbr/\u003E- ограничивает колебания артериального давления, вызванные физической нагрузкой, без значительных изменений частоты сердечных сокращений; \u003Cbr/\u003E- значительно снижает частоту приступов стенокардии и потребность в приеме нитроглицерина короткого действия; \u003Cbr/\u003E- улучшает сократительную функцию левого желудочка у пациентов с ишемической дисфункцией. \u003Cbr/\u003EРезультаты проведенных клинических исследований подтвердили эффективность и безопасность применения триметазидина у пациентов со стабильной стенокардией, как в монотерапии, так и в составе комбинированной терапии при недостаточном эффекте других антиангинальных препаратов. \u003Cbr/\u003EВ исследовании с участием 426 пациентов со стабильной стенокардией добавление триметазидина (60 мг/сут) к терапии метопрололом 100мг/сут (50 мг 2 раза/сутки) в течение 12 недель статистически достоверно улучшило результаты нагрузочных тестов и клинические симптомы по сравнению с плацебо: общая длительность нагрузочных тестов, общее время выполнения нагрузки, время до развития депрессии сегмента ST на 1 мм, время до развития приступа стенокардии, количество приступов стенокардии в неделю и потребление нитратов короткого действия в неделю, без гемодинамических изменений. \u003Cbr/\u003EВ исследовании с участием 223 пациентов со стабильной стенокардией добавление триметазидина в дозе 35 мг (2 раза/сутки) к терапии атенололом в дозе 50 мг (1 раз/сутки) в течение 8 недель приводило к увеличению времени до развития ишемической депрессии сегмента ST на 1 мм при проведении нагрузочных тестов в подгруппе пациентов по сравнению с плацебо. Существенная разница также была показана для времени развития приступов стенокардии. Не выявлено достоверных различий между группами для других вторичных конечных точек (общая длительность нагрузочных тестов, общее время нагрузки и клинические конечные точки). \u003Cbr/\u003EВ исследовании с участием 1962 пациентов со стабильной стенокардией триметазидин в двух дозировках (70 мг/сут и 140 мг/сут) в сравнении с плацебо был добавлен к терапии атенололом 50 мг/сут. В общей популяции, включая пациентов, как без симптомов, так и с симптомами стенокардии, триметазидин не продемонстрировал преимуществ по эргометрическим и клиническим конечным точкам. Однако, в ретроспективном анализе в подгруппе пациентов с симптомами стенокардии, триметазидин (140 мг) значительно улучшил общее время нагрузочного теста и время до развития приступа стенокардии. \u003Cbr/\u003E"},{"name":"Фармакологическая группа","value":"антиангинальное средство"},{"name":"Форма выпуска","value":"таблетки с пролонгированным высвобождением"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25° С. \u003Cbr/\u003EХранить в недоступном для детей месте. \u003Cbr/\u003EНе применять по истечении срока годности."},{"name":"Передозировка","value":"Имеется лишь очень ограниченная информация о передозировке триметазидина. В случае передозировки следует проводить симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr/\u003EДанные о применении триметазидина у беременных отсутствуют. Исследования на животных не выявили наличие прямой или непрямой репродуктивной токсичности. Применение триметазидина во время беременности противопоказано. \u003Cbr/\u003EПериод грудного вскармливания\u003Cbr/\u003EДанные о выделении триметазидина или его метаболитов в грудное молоко отсутствуют. Риск для новорожденного/ребенка не может быть исключен. При необходимости применения препарата в период грудного вскармливания, грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В ходе клинических исследований, не было выявлено влияния триметазидина на показатели гемодинамики, однако, в период пострегистрационного применения, наблюдались случаи головокружения и сонливости, что может повлиять на способность к управлению транспортными средствами и механизмами."},{"name":"Особые указания","value":"С осторожностью применяют: \u003Cbr/\u003E- Пациенты с печеночной недостаточностью тяжелой степени тяжести (от 10 до 15 баллов по шкале Чайлд-Пью). \u003Cbr/\u003E- Пациенты с почечной недостаточностью умеренной степени тяжести (клиренс креатинина 30-60 мл/мин). \u003Cbr/\u003E- Пациенты старше 75 лет. \u003Cbr/\u003EПрепарат не предназначен для купирования приступов стенокардии и не показан для начального курса терапии нестабильной стенокардии или инфаркта миокарда на догоспитальном этапе или в первые дни госпитализации. \u003Cbr/\u003EВ случае развития приступа стенокардии следует вновь оценить степень поражения коронарных артерий и, при необходимости, адаптировать лечение (лекарственную терапию или возможное проведение процедуры реваскуляризации). Триметазидин может вызывать или ухудшать симптомы паркинсонизма (тремор, акинезию, повышение тонуса), поэтому следует проводить регулярное наблюдение пациентов, особенно пожилого возраста. В сомнительных случаях пациенты должны быть направлены к неврологу для соответствующего обследования. \u003Cbr/\u003EПри появлении двигательных нарушений, таких как симптомы паркинсонизма, синдром «беспокойных ног», тремор, «шаткость» походки, препарат следует окончательно отменить. \u003Cbr/\u003EТакие случаи редки и симптомы обычно проходят после прекращения терапии: у большинства пациентов - в течение 4 месяцев после отмены препарата. Если симптомы паркинсонизма сохраняются более 4 месяцев после отмены, следует проконсультироваться у невролога. \u003Cbr/\u003EМогут отмечаться случаи падения, связанные с неустойчивостью походки или артериальной гипотензией, особенно, у пациентов, принимающих гипотензивные препараты. Следует с осторожностью назначать препарат пациентам, у которых возможно повышение его экспозиции: \u003Cbr/\u003E- при умеренной почечной недостаточности. \u003Cbr/\u003E - у пожилых пациентов старше 75 лет. \u003Cbr/\u003E Ввиду лекарственной формы препарата «таблетки с пролонгированным высвобождением, покрытые пленочной оболочкой», гелеобразный каркас таблетки препарата может не раствориться в кишечнике и выделиться с калом, что не влияет на терапевтическую эффективность препарата."},{"name":"Взаимодействие","value":"Не было выявлено взаимодействий с другими лекарственными средствами. Пациент должен сообщить врачу обо всех принимаемых препаратах."},{"name":"Регистрационный номер","value":"ЛП-007527"},{"name":"Дата государственной регистрации","value":"21.10.2021"},{"name":"Владелец регистрационного удостоверения","value":"Вертекс","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:8514228"]}}},{"name":"Изготовитель","value":"Вертекс"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Тримектал","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:18017727"]}}},{"name":"Срок годности","value":"566 дн."}]}},"fullSpecsGrouped":{"5357457133146451374":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"ишемическая болезнь сердца, профилактика приступов стенокардии"},{"name":"Показания к применению","value":"- длительная терапия ишемической болезни сердца: профилактика приступов стабильной стенокардии в составе моно- или комбинированной терапии."},{"name":"Противопоказания","value":"- Повышенная чувствительность к действующему веществу или любому из вспомогательных веществ, входящих в состав лекарственного препарата. \u003Cbr/\u003E- Болезнь Паркинсона, симптомы паркинсонизма, тремор, синдром «беспокойных ног» и другие связанные с ними двигательные нарушения. \u003Cbr/\u003E- Тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин). \u003Cbr/\u003E- Из-за отсутствия достаточного количества клинических данных, пациентам до 18 лет назначение препарата не рекомендуется. \u003Cbr/\u003E- Беременность и период грудного вскармливания."},{"name":"Состав","value":"Одна таблетка содержит: \u003Cbr/\u003Eдействующее вещество: триметазидина дигидрохлорид - 80,00 мг; \u003Cbr/\u003Eвспомогательные вещества: гипромеллоза, крахмал кукурузный прежелатинизированный, магния стеарат, кремния диоксид коллоидный; \u003Cbr/\u003Eпленочная оболочка № 1: [гипромеллоза, тальк, титана диоксид, макрогол 4000 (полиэтиленгликоль 4000)] или [сухая смесь для пленочного покрытия, содержащая гипромеллозу, тальк, титана диокид, макрогол 4000 (полиэтиленгликоль 4000)]; \u003Cbr/\u003Eпленочная оболочка № 2: водная дисперсия этилцеллюлозы для пленочного покрытия, содержащая этилцеллюлозу, аммиака раствор 28 %, триглицериды среднецепочечные, олеиновую кислоту в пересчете на сухое вещество."},{"name":"Действующее вещество","value":"Триметазидин"},{"name":"Способ применения и дозы","value":"Внутрь, по 1 таблетке 1 раз в сутки, утром, во время завтрака. \u003Cbr/\u003EТаблетки следует принимать целиком, не разжевывая, запивая водой. \u003Cbr/\u003EОценка пользы от лечения может быть проведена после трех месяцев приема препарата. Прием препарата следует прекратить, если за это время улучшения не наступило. Продолжительность лечения определяется врачом. \u003Cbr/\u003EПациенты пожилого возраста\u003Cbr/\u003EУ пациентов старше 75 лет может наблюдаться повышенная экспозиция триметазидина из-за возрастного снижения функции почек, У пациентов с почечной недостаточностью умеренной степени тяжести (КК 30-60 мл/мин), рекомендуется снижение дозы, т.е. 1 таблетка, содержащая 35 мг триметазидина в день. Подбор дозы у пациентов старше 75 лет должен происходить с осторожностью. \u003Cbr/\u003EПациенты с нарушением функции почек\u003Cbr/\u003EУ пациентов с почечной недостаточностью умеренной степени тяжести (КК 30-60 мл/мин) рекомендуется снижение дозы, т.е. 1 таблетка, содержащая 35 мг триметазидина в день. \u003Cbr/\u003EПациенты с нарушением функции печени\u003Cbr/\u003EСледует проявлять осторожность при лечении пациентов с печеночной недостаточностью тяжелой степени тяжести ввиду того, что имеющиеся данные ограничены и не позволяют полностью исключить отсутствие влияния нарушений функции печени на метаболизм триметазидина. \u003Cbr/\u003EПациенты детского возраста\u003Cbr/\u003EБезопасность и эффективность применения триметазидина у пациентов младше 18 лет не установлены. Данные отсутствуют."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной организации здравоохранения (ВОЗ): \u003Cbr/\u003EОчень часто ≥ 1/10; \u003Cbr/\u003EЧасто от ≥ 1/100 до \u003C 1/10; \u003Cbr/\u003EНечасто от ≥ 1/1000 до \u003C 1/100; \u003Cbr/\u003EРедко от ≥ 1/10000 до \u003C 1/1000; \u003Cbr/\u003EОчень редко \u003C 1/10000, включая отдельные сообщения; \u003Cbr/\u003Eчастота неизвестна - по имеющимся данным установить частоту возникновения не представляется возможным. \u003Cbr/\u003EНарушения со стороны крови и лимфатической систем: \u003Cbr/\u003Eчастота неизвестна - агранулоцитоз, тромбоцитопения, тромбоцитопеническая пурпура. \u003Cbr/\u003EНарушения со стороны нервной системы: \u003Cbr/\u003Eчасто - головокружение, головная боль; \u003Cbr/\u003Eчастота неизвестна - симптомы паркинсонизма (тремор, акинезия, повышение тонуса), «шаткость» походки, синдром «беспокойных ног», другие связанные с ними двигательные нарушения, обычно обратимые после прекращения терапии. Нарушения сна (бессонница, сонливость). \u003Cbr/\u003EНарушения со стороны органа слуха и лабиринта: \u003Cbr/\u003Eчастота неизвестна - вертиго. \u003Cbr/\u003EНарушения со стороны сердца: \u003Cbr/\u003Eредко - ощущение сердцебиения, экстрасистолия, тахикардия. \u003Cbr/\u003EНарушения со стороны сосудов: \u003Cbr/\u003Eредко - артериальная гипотензия, ортостатическая гипотензия, которая может сопровождаться общей слабостью, головокружением или потерей равновесия, особенно при одновременном приеме гипотензивных препаратов, «приливы» крови к коже лица. \u003Cbr/\u003EЖелудочно-кишечные нарушения: \u003Cbr/\u003Eчасто - боль в животе, диарея, диспепсия, тошнота, рвота; частота неизвестна - запор. \u003Cbr/\u003EНарушения со стороны печени и желчевыводящих путей: \u003Cbr/\u003Eчастота неизвестна - гепатит. \u003Cbr/\u003EНарушения со стороны кожи и подкожной клетчатки: \u003Cbr/\u003Eчасто - кожная сыпь, зуд, крапивница; \u003Cbr/\u003Eчастота неизвестна - острый генерализованный экзантематозный пустулез, отек Квинке. \u003Cbr/\u003EОбщие нарушения и реакции в месте введения:\u003Cbr/\u003Eчасто - астения."},{"name":"Фармакологическое действие","value":"Механизм действия\u003Cbr/\u003EТриметазидин предотвращает снижение внутриклеточной концентрации аденозинтрифосфата (АТФ) путем сохранения энергетического метаболизма клеток в состоянии гипоксии. Таким образом, триметазидин обеспечивает нормальное функционирование мембранных ионных каналов, трансмембранный перенос ионов калия и натрия и сохранение клеточного гомеостаза. \u003Cbr/\u003EТриметазидин ингибирует окисление жирных кислот за счет селективного ингибирования фермента 3-кетоацил-КоА-тиолазы (3-КАТ) митохондриальной длинноцепочечной изоформы жирных кислот, что приводит к усилению окисления глюкозы и ускорению гликолиза с окислением глюкозы, что и обусловливает защиту миокарда от ишемии. Переключение энергетического метаболизма с окисления жирных кислот на окисление глюкозы лежит в основе фармакологических свойств триметазидина. \u003Cbr/\u003EФармакодинамические свойства: \u003Cbr/\u003E- поддерживает энергетический метаболизм сердца и нейросенсорных тканей во время ишемии; \u003Cbr/\u003E- уменьшает выраженность внутриклеточного ацидоза и изменений трансмембранного ионного потока, возникающих при ишемии; \u003Cbr/\u003E- понижает уровень миграции и инфильтрации полинуклеарных нейтрофилов в ишемизированных и реперфузированных тканях сердца; \u003Cbr/\u003E- уменьшает размер повреждения миокарда; \u003Cbr/\u003E- не оказывает прямого воздействия на показатели гемодинамики. \u003Cbr/\u003EУ пациентов со стенокардией триметазидин: \u003Cbr/\u003E- увеличивает коронарный резерв, тем самым замедляя наступление ишемии, вызванной физической нагрузкой, начиная с 15-го дня терапии; \u003Cbr/\u003E- ограничивает колебания артериального давления, вызванные физической нагрузкой, без значительных изменений частоты сердечных сокращений; \u003Cbr/\u003E- значительно снижает частоту приступов стенокардии и потребность в приеме нитроглицерина короткого действия; \u003Cbr/\u003E- улучшает сократительную функцию левого желудочка у пациентов с ишемической дисфункцией. \u003Cbr/\u003EРезультаты проведенных клинических исследований подтвердили эффективность и безопасность применения триметазидина у пациентов со стабильной стенокардией, как в монотерапии, так и в составе комбинированной терапии при недостаточном эффекте других антиангинальных препаратов. \u003Cbr/\u003EВ исследовании с участием 426 пациентов со стабильной стенокардией добавление триметазидина (60 мг/сут) к терапии метопрололом 100мг/сут (50 мг 2 раза/сутки) в течение 12 недель статистически достоверно улучшило результаты нагрузочных тестов и клинические симптомы по сравнению с плацебо: общая длительность нагрузочных тестов, общее время выполнения нагрузки, время до развития депрессии сегмента ST на 1 мм, время до развития приступа стенокардии, количество приступов стенокардии в неделю и потребление нитратов короткого действия в неделю, без гемодинамических изменений. \u003Cbr/\u003EВ исследовании с участием 223 пациентов со стабильной стенокардией добавление триметазидина в дозе 35 мг (2 раза/сутки) к терапии атенололом в дозе 50 мг (1 раз/сутки) в течение 8 недель приводило к увеличению времени до развития ишемической депрессии сегмента ST на 1 мм при проведении нагрузочных тестов в подгруппе пациентов по сравнению с плацебо. Существенная разница также была показана для времени развития приступов стенокардии. Не выявлено достоверных различий между группами для других вторичных конечных точек (общая длительность нагрузочных тестов, общее время нагрузки и клинические конечные точки). \u003Cbr/\u003EВ исследовании с участием 1962 пациентов со стабильной стенокардией триметазидин в двух дозировках (70 мг/сут и 140 мг/сут) в сравнении с плацебо был добавлен к терапии атенололом 50 мг/сут. В общей популяции, включая пациентов, как без симптомов, так и с симптомами стенокардии, триметазидин не продемонстрировал преимуществ по эргометрическим и клиническим конечным точкам. Однако, в ретроспективном анализе в подгруппе пациентов с симптомами стенокардии, триметазидин (140 мг) значительно улучшил общее время нагрузочного теста и время до развития приступа стенокардии. \u003Cbr/\u003E"},{"name":"Фармакологическая группа","value":"антиангинальное средство"},{"name":"Форма выпуска","value":"таблетки с пролонгированным высвобождением"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25° С. \u003Cbr/\u003EХранить в недоступном для детей месте. \u003Cbr/\u003EНе применять по истечении срока годности."},{"name":"Передозировка","value":"Имеется лишь очень ограниченная информация о передозировке триметазидина. В случае передозировки следует проводить симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr/\u003EДанные о применении триметазидина у беременных отсутствуют. Исследования на животных не выявили наличие прямой или непрямой репродуктивной токсичности. Применение триметазидина во время беременности противопоказано. \u003Cbr/\u003EПериод грудного вскармливания\u003Cbr/\u003EДанные о выделении триметазидина или его метаболитов в грудное молоко отсутствуют. Риск для новорожденного/ребенка не может быть исключен. При необходимости применения препарата в период грудного вскармливания, грудное вскармливание необходимо прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В ходе клинических исследований, не было выявлено влияния триметазидина на показатели гемодинамики, однако, в период пострегистрационного применения, наблюдались случаи головокружения и сонливости, что может повлиять на способность к управлению транспортными средствами и механизмами."},{"name":"Особые указания","value":"С осторожностью применяют: \u003Cbr/\u003E- Пациенты с печеночной недостаточностью тяжелой степени тяжести (от 10 до 15 баллов по шкале Чайлд-Пью). \u003Cbr/\u003E- Пациенты с почечной недостаточностью умеренной степени тяжести (клиренс креатинина 30-60 мл/мин). \u003Cbr/\u003E- Пациенты старше 75 лет. \u003Cbr/\u003EПрепарат не предназначен для купирования приступов стенокардии и не показан для начального курса терапии нестабильной стенокардии или инфаркта миокарда на догоспитальном этапе или в первые дни госпитализации. \u003Cbr/\u003EВ случае развития приступа стенокардии следует вновь оценить степень поражения коронарных артерий и, при необходимости, адаптировать лечение (лекарственную терапию или возможное проведение процедуры реваскуляризации). Триметазидин может вызывать или ухудшать симптомы паркинсонизма (тремор, акинезию, повышение тонуса), поэтому следует проводить регулярное наблюдение пациентов, особенно пожилого возраста. В сомнительных случаях пациенты должны быть направлены к неврологу для соответствующего обследования. \u003Cbr/\u003EПри появлении двигательных нарушений, таких как симптомы паркинсонизма, синдром «беспокойных ног», тремор, «шаткость» походки, препарат следует окончательно отменить. \u003Cbr/\u003EТакие случаи редки и симптомы обычно проходят после прекращения терапии: у большинства пациентов - в течение 4 месяцев после отмены препарата. Если симптомы паркинсонизма сохраняются более 4 месяцев после отмены, следует проконсультироваться у невролога. \u003Cbr/\u003EМогут отмечаться случаи падения, связанные с неустойчивостью походки или артериальной гипотензией, особенно, у пациентов, принимающих гипотензивные препараты. Следует с осторожностью назначать препарат пациентам, у которых возможно повышение его экспозиции: \u003Cbr/\u003E- при умеренной почечной недостаточности. \u003Cbr/\u003E - у пожилых пациентов старше 75 лет. \u003Cbr/\u003E Ввиду лекарственной формы препарата «таблетки с пролонгированным высвобождением, покрытые пленочной оболочкой», гелеобразный каркас таблетки препарата может не раствориться в кишечнике и выделиться с калом, что не влияет на терапевтическую эффективность препарата."},{"name":"Взаимодействие","value":"Не было выявлено взаимодействий с другими лекарственными средствами. Пациент должен сообщить врачу обо всех принимаемых препаратах."},{"name":"Регистрационный номер","value":"ЛП-007527"},{"name":"Дата государственной регистрации","value":"21.10.2021"},{"name":"Владелец регистрационного удостоверения","value":"Вертекс"},{"name":"Изготовитель","value":"Вертекс"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Тримектал"},{"name":"Срок годности","value":"566 дн."}]}],"transitionId":"tr_10670355498471340514"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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1 319 ₽

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    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 660 ₽
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  • Триметазидин МВ таб. модиф. высвоб. п/о плен., 35 мг, 60 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o9u61z1tk5/toggleWishlist":{"skuId":"662548051","productId":1401075936,"offerId":"LCw24rruWLrMImSVZqzApQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI4PGKnAUQ09z2uwIYjIHPBiDX3MEH","sign":"nGL01ONy7FeQIgDMN96hLCRsO3K2LD8FIflD0149dJQ="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o9u61z1tk5/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Триметазидин МВ таб. модиф. высвоб. п/о плен., 35 мг, 60 шт.

    Рейтинг товара: 4.5 из 5
    на основе 31 оценка
    Цена 224 ₽
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  • Депренорм ОД таб. пролонг. высвоб. п/о плен., 70 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-3i0a2uzbzp/toggleWishlist":{"skuId":"101594763760","productId":833199064,"offerId":"5C_ZWtjq7NTdpI4S8BQg3A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI2LemjQMQ8KOUvPoCGM7C2Qcg19zBBw==","sign":"AygI9S+UeGubN8DOn4vidgpwGFO0Zb6bgHPSWisnBls="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-3i0a2uzbzp/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Депренорм ОД таб. пролонг. высвоб. п/о плен., 70 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 540 ₽
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  • Верапамил таб. п/о плен., 40 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cql9x72lu1v/toggleWishlist":{"skuId":"228042234","productId":1401075599,"offerId":"82VwWWQcFaPK7O7D__NvBA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIj++KnAUQ+svebBjk4NAHINfcwQc=","sign":"VFT5baxrGrOevkZ2jvQQrb4LiANGaNmJrnllIJUjA44="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cql9x72lu1v/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Верапамил таб. п/о плен., 40 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 6 оценок
    Цена 55 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-cql9x72lu1v/addToCartButton":{"offerId":"82VwWWQcFaPK7O7D__NvBA","skuId":"228042234","pendingCartItem":{"productId":1401075599,"offerId":"82VwWWQcFaPK7O7D__NvBA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMi308g334ZgMUl8Y-bzUjLtnK6iSiCZyY-a7xuNOGloEcPpBWS-Sd4xTMV-S16DL-pf1wXKvR1t4W5JFbUl9NCO1M40p2_sfkorQH_BusXcldwcT0nV8Qw_IMGgM_o2pMlMmJ97gtdy7NhgcBgIPEHZOh1slR0OxiMr5wl4FjcbxUq-dZsz2TbxK0XRLku4Ceg,,","feeShow":"OTNDnItfwRMjN9MRHuEMMi308g334ZgMUl8Y-bzUjLtnK6iSiCZyY-a7xuNOGloEcPpBWS-Sd4xTMV-S16DL-pf1wXKvR1t4W5JFbUl9NCO1M40p2_sfkorQH_BusXcldwcT0nV8Qw_IMGgM_o2pMlMmJ97gtdy7NhgcBgIPEHZOh1slR0OxiMr5wl4FjcbxUq-dZsz2TbxK0XRLku4Ceg,,","skuId":"228042234","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"55","currency":"RUR"},"hid":"15756887","name":"Верапамил таб. п/о плен., 40 мг, 30 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  • Бисопролол Реневал таб. п/о плен., 5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-42sin6sh4du/toggleWishlist":{"skuId":"101762663758","productId":1754834159,"offerId":"6_EmMXajAMKDm99g_CYjaQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI78nixAYQzoqcjPsCGPKsgggg19zBBw==","sign":"vWcLm5rygfFdWR4GkGIzSJ1wR/2vSMj5lMuxiHPkARM="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-42sin6sh4du/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Бисопролол Реневал таб. п/о плен., 5 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 45 оценок
    Цена 99 ₽
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  • Бисопролол Канон таб. п/о плен., 2.5 мг, 30 шт.
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    Бисопролол Канон таб. п/о плен., 2.5 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 95 оценок
    Цена 93 ₽
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  • Триметазидин мв таб. пролонг. высвоб. п/о плен., 35 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-oco359vfue/toggleWishlist":{"skuId":"228090683","productId":1401075802,"offerId":"dFVVL5gyC_JWeqYvZ3QaRA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI2vCKnAUQu8bhbBiEqbIIINfcwQc=","sign":"w1conGH3dCTUhfwRPdfSvBUT71YKhmHvJRkG1KYwFqg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-oco359vfue/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Триметазидин мв таб. пролонг. высвоб. п/о плен., 35 мг, 30 шт.

    Рейтинг товара: 3.7 из 5
    на основе 3 оценки
    Цена 257 ₽
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  • Плагрил таб. п/о плен., 75 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-szj1hld8lu/toggleWishlist":{"skuId":"101914772756","productId":1810550779,"offerId":"Iux6DSJfdx28hAJo1d4WUg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI+5+r3wYQlIrg1PsCGMCi1Qcg19zBBw==","sign":"IQa9w+Cdjrgol8CAORhmv/VfQ0yNvGWAWFrYwIbDW6E="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-szj1hld8lu/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Плагрил таб. п/о плен., 75 мг, 30 шт.

    Цена 621 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-szj1hld8lu/addToCartButton":{"offerId":"Iux6DSJfdx28hAJo1d4WUg","skuId":"101914772756","pendingCartItem":{"productId":1810550779,"offerId":"Iux6DSJfdx28hAJo1d4WUg","showPlaceId":"OTNDnItfwRMjN9MRHuEMMi308g334ZgMbCov2lV-mRL0Yws-gb6jbSnq-XXB1n36cOHfJfkG9UG1FKonFHQ--6-X7gvd4EwODlJxbRbYbtQLkc-FYqhaX_2MwewHitPVO-MHY97GN4KVNewaRpAtKrdLxHXi59sMTUnTbJH7GVeCCFHHAob1qGLBcU875AjGJH3sCLav3UPUqySltTa9cA,,","feeShow":"OTNDnItfwRMjN9MRHuEMMi308g334ZgMbCov2lV-mRL0Yws-gb6jbSnq-XXB1n36cOHfJfkG9UG1FKonFHQ--6-X7gvd4EwODlJxbRbYbtQLkc-FYqhaX_2MwewHitPVO-MHY97GN4KVNewaRpAtKrdLxHXi59sMTUnTbJH7GVeCCFHHAob1qGLBcU875AjGJH3sCLav3UPUqySltTa9cA,,","skuId":"101914772756","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"621","currency":"RUR"},"hid":"15756887","name":"Плагрил таб. п/о плен., 75 мг, 30 шт.","label":"9ie66x6uegj","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":7632591,"key":"img_id7931829703814116604.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96UWkyu_L0koKYok6hYzEHW1XZFGfxnS2l9tgr2WDgBNpPBwZXQOdR02DJV0Lh9nir51UT4pveA3lsui-J_nJHGZX4FnpalMI1fH4wdZVj0FCpDBDkB02kRBWbLJL7ZKSdEs6pE7PX2n5-aNWN70bVsQIo2-Qh2iif63Fy1cOlIzVB7jB3AjJgNW0IkY6Xx5mAkNO9qAJaH_3CWDdo0f_hOVav6fqaY-bdPWrwJbEoNBAkiiLZOFoPAigclbfhIGosRww2dWHJVhNVxeIRJgzGsUKqa1iYMcNtbyg2dHQPxQlNOs1cdmyQRrWIItxyFpUaueuJ43Pji2mcypmVNvbFHrK2oO1gaG2hpUuBvdhppYI22_DWmXYuANHz4ZfmyNAoVDbZBim0Rt_mPC-SPA5tK2hqehqYpydjvWr-YnAKBIRaTn0MO1rEPc6hcO5oE8YZh1LlaaUpbLcG6Hx9geHE1pwfrAw3Ab_2ridctl3NKkoi3VUoZX1lveX7RL0fbDicPaL87FALYv9smgXtSjxb2lRkIfcjhTyqvhMAll3jp02cLN8GL8l8zjE_uuJynDh4Ni5vrwUFPMZm4wQZibf0QGgtPtlbgwuNRxxoHbj7WTDIRFu_No_5DFJCro2s3P8GSXvnwwWRfFNS2EtXcJXiictLS0vYij-xIgQ--mWAHTLITUOoLVjIa_u7c1KxR1d5etv5jaVEyyRd1oY_-kcnAQEcUb6fMrsVuyadW5f4FNr4Xa6SRhbYHMhJFzJ8sE1Rpmb84lEoOAt14P3h9wjIO83a7iFoVNcQdyrBhxN0OP9PmfxIlnljS1pHjHHG9Y3-gw8hzfD3OSVi2U-sCune219glhr2UsefPmADrKfytQBUdAxjB_a1kTm3sMhyg9SOxQ5wZFMtZ7tEG5F_InRHH2xKULACAOPNNFn5OuJKTZdx0KG_4mN1qYqh3yZsjEAdhTYlJ9rVaMWsj_Egvj4RoONnvHcW8cCgE3PKIneiPoe3zF7TRLiorAQiAZUKkduvhGalR2vu0aab1hV7k0VX7JSro65aPajNvfCkJ4X9pZRdRSLkuJRzMsVKZnMYgvd0VDkNRCJJt3cQJ2utwjkOyncyaBwk8Eywb55nnOEt_WRNMR_jW8nclufrayb82hX1Wv42vR4A6Ffbt8heFH5T3tkHo-C9B4ruQyJ02d4gZge72LoZqmguMRFeVfZ7GC7HujIeWeMiVpJzve7PmeIcwuwoZCO6e3xuK6Q3NWpdHoestM6r-U3hDEtagHAwvWmAGsT-AqHwuzNttqCpqTr4NwDLh3k-y7zpuTgq9-mUhyC4cvstveGmVS-7ymdpzWTDu3H5etAiDz7qHZwA7iEU-FBlqqp3dOxOVBsHoe8uu0gMEwN1cBeBMXyoiKmMbikIwzCZ38hC19OD2oU1W6DFKy7kERUDmMsJhfksytQM3gWp4AJKcqFGvt2sVbh_ecgb4J0_wexG_BGs0d6F0plBVuAh2JuIRyBVT0LcB0cjdYJTSO3NNL9deVwNFnolSTe0REuk2YkIuvDTf5xZHnnjbi3G6XxIzsaNhEZQsViqJbB078Xw7VI10XAmdNb4gfLaMXpY-nYSmKSGPM58aarOqJaUW64I091uEglpADzPTyf8mkrFr5iVgXadZaGoBzX1AiCWO6j35AK8XVTdvm79hqAdQ_cDMSPJTxHr-PYoMpKTwvg7xXmX3kf197z2kLscX2jH3dzB7Fi-Vao4ZEOR9f8yYdFmJScBdlODuA6DxRg7BEKBqRuZ6xtdbxL_C3v0k_2nvGLaSSCUAFEPCGEWEn5vn0UJcGRWV1HTpnPbQougA_dJ4sIYZDihD8tzV8xxsT1VncqO_6cfsivga8kG2fvo7HKw9JlUf1VoFh6WDHnNsWqtZEDoDsc0jheLvl1o6RJe5Ty5h9NHYGd6Uaq4X_-HdUOJNhymZbGh-5lnDrdTJ2o8PkzUDTEAy_6vlpGtqvLHAGubJERn4yQ4KM0hwTZjol3jfhGckrrpeh7WZj3xWJToJxv30DB1lAEvbwgBBlpZkJmX9PggQDmiiz8Nwyi6afCdpFeRi7GKNkvbqO6oO46_5G24QnWGSh5i3id3hERk699FMXyhomDlpTr1Z5JG1JYPnivJ-4x8FJ7EHdR0ZjklvpfVwo1nV2BcPR5M00BUbRP3UIKeezvX5QaOQgb0HO3iGHbupuLYuDjum67wyfEAjjDHrlMyD1liSQTxp87A7y4Iy0rSEuwe63JJJSFnCno0QSGNx9GX85VfMWk0C-bNa9sLBPfMNUwpUTwCMw0h4fg3SrddHcDAqFTdsq5vbFrGP4ykzykeeK0RtRL8Y1lW6NZd8z-LianIg3-HM3kkdlbP6HVtHSYd_zZeG8N2nWAEAw_1ut6E1NCKlPfuyc8hEkJN7WSbRFBWOu5pb4QzjEvL7B56BE_zYbwHQ0xBR-8v6n6ZGdtnIYHydcl8a5BFYYKOX607XzEB2LJU4_Qzo3svBK5WuupeFKBlkpS6cOs1ZV98W6av5sUREoJ4RiQZnbwgG_ZmClAMH5ZepW5gqvVW1J6hgDCpm_xTuXFvxSiQbSN6MDVz_7zAyDwoM09BfPoDgGae6QbjhrgBXfmz142Y1f15NgHccWg-_lZz4FxUNAkEO-Pq8PTBHy9SIhM1Nyzln2871btX_a3yoWSsWTvCWcnxZlrIU4L6rNmEA6bxEVfBIzznNFcg9cRLF5WLLJog5br3Xz-ZqMcKDOCnuENQLib5_EO5CK3sZyhCX764iwKdyOJ7X_WcYql7vzbcwKjbnxGFM4xdhy7Udb53LcRl1DKrLtAc7W7cFva4pO_L6UUG_oh10PLRkAaq-Pwl15Kh5pZ4kVokE7noZen2vvC3-cAb-R98p5X6uB5MTs1nLZ5IewUV64hhvpNGFtzcmcf_a7g82fuitq8sl2ILbQwAIlxM4gHiXREWIFCS7Jx7vFehG-woiHRdTlptJM7c2AIJaYbw5RXW9SSbNmJ9ErxktgVrjEKNDSrAxaV3pLsqVMisADqfzmdkFWJ7x2ehXIl9iCxZd137Az0YaGiZRRaLVN7p4KUWIL8kctOgx4vIjiQgof5eZKTW1vx9bRDbeZ84TQBJBCRB74bvG5ocTlY-iescyEhP5QJ151VDwZdIcTtXdajdrHxNBRCipGDz7VHhfWQmXITrOlXvBR7yiRHWOw6K2_XRCIfHrDHOsAp5T9YMxIfI7wz8O2jELoe1Ty9YEVACZ_cyoshDV81wvOe23I4Q,,/b64e=1/sign=263e737bb104a34f2edb02ffccebb78d/keyno=MARKET_1/*","showUid":"17179920527235304727806009","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI+5+r3wYQlIrg1PsCGMCi1Qcg19zBBw==","sign":"IQa9w+Cdjrgol8CAORhmv/VfQ0yNvGWAWFrYwIbDW6E="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI+5+r3wYQlIrg1PsCGMCi1Qcg19zBBw==","sign":"IQa9w+Cdjrgol8CAORhmv/VfQ0yNvGWAWFrYwIbDW6E="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-szj1hld8lu/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Триметазидин таб. п/о плен., 20 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kpuhevh2r6d/toggleWishlist":{"skuId":"634116303","productId":1401075509,"offerId":"sVxFNZ3lQnQvraxal23zJg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIte6KnAUQz7GvrgIY1/HPBiDX3MEH","sign":"3DBL/YeeDl1gc6yd3yrijomvxbZ9rVsyW2RgKn5g6ec="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kpuhevh2r6d/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Триметазидин таб. п/о плен., 20 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 12 оценок
    Цена 235 ₽
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  • Лориста таб. п/о плен., 25 мг, 30 шт.
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    Лориста таб. п/о плен., 25 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 34 оценки
    Цена 119 ₽
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  • Триметазидин-АКОС МВ таб. с модифиц. высвоб. п/о плен., 35 мг, 60 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-x2narrcm1pj/toggleWishlist":{"skuId":"101760546709","productId":1741773236,"offerId":"Mw53aoVeaqxmXkCf_jIbRQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQrpSttc6qnLpOEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcItLPFvgYQle+ai/sCGKbf0Acg19zBBw==","sign":"qv3ZMtMdm1wQFfNQDGzM6t2ktv8dsyGD67puL65n+2s="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-x2narrcm1pj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Триметазидин-АКОС МВ таб. с модифиц. высвоб. п/о плен., 35 мг, 60 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 355 ₽
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Инструкция

Показания к применению

- длительная терапия ишемической болезни сердца: профилактика приступов стабильной стенокардии в составе моно- или комбинированной терапии.

Противопоказания

- Повышенная чувствительность к действующему веществу или любому из вспомогательных веществ, входящих в состав лекарственного препарата.
- Болезнь Паркинсона, симптомы паркинсонизма, тремор, синдром «беспокойных ног» и другие связанные с ними двигательные нарушения.
- Тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин).
- Из-за отсутствия достаточного количества клинических данных, пациентам до 18 лет назначение препарата не рекомендуется.
- Беременность и период грудного вскармливания.

Способ применения и дозы

Внутрь, по 1 таблетке 1 раз в сутки, утром, во время завтрака.
Таблетки следует принимать целиком, не разжевывая, запивая водой.
Оценка пользы от лечения может быть проведена после трех месяцев приема препарата. Прием препарата следует прекратить, если за это время улучшения не наступило. Продолжительность лечения определяется врачом.
Пациенты пожилого возраста
У пациентов старше 75 лет может наблюдаться повышенная экспозиция триметазидина из-за возрастного снижения функции почек, У пациентов с почечной недостаточностью умеренной степени тяжести (КК 30-60 мл/мин), рекомендуется снижение дозы, т.е. 1 таблетка, содержащая 35 мг триметазидина в день. Подбор дозы у пациентов старше 75 лет должен происходить с осторожностью.
Пациенты с нарушением функции почек
У пациентов с почечной недостаточностью умеренной степени тяжести (КК 30-60 мл/мин) рекомендуется снижение дозы, т.е. 1 таблетка, содержащая 35 мг триметазидина в день.
Пациенты с нарушением функции печени
Следует проявлять осторожность при лечении пациентов с печеночной недостаточностью тяжелой степени тяжести ввиду того, что имеющиеся данные ограничены и не позволяют полностью исключить отсутствие влияния нарушений функции печени на метаболизм триметазидина.
Пациенты детского возраста
Безопасность и эффективность применения триметазидина у пациентов младше 18 лет не установлены. Данные отсутствуют.
Полная инструкция
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Тримектал ОД таб. пролонг. действ. п/о плен.
Тримектал ОД таб. пролонг. действ. п/о плен., 80 мг, 60 шт.
У продавца: 
нет • На Маркете: 5.0
(12)
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1 вопрос
Инструкция

1 319 ₽

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