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Описание

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Кетопрофен ДС р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 5 шт.

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Нет отзывов
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Коротко о товаре

Артикул Маркета
4453164488
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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головная боль; посттравматический и послеоперационный болевой синдром; болевой синдром при онкологических заболеваниях; альгодисменорея."},{"name":"Противопоказания","value":"- гиперчувствительность к кетопрофену или другим компонентам препарата, а также салицилатам или другим НПВП; \u003Cbr /\u003E- полное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе); \u003Cbr /\u003E- эрозивно-язвенные поражения желудочно-кишечного тракта и двенадцатиперстной кишки; \u003Cbr /\u003E- воспалительные заболевания кишечника (язвенный колит (обострение), болезнь Крона (обострение)); \u003Cbr /\u003E- гемофилия и другие нарушения свертываемости крови; \u003Cbr /\u003E- декомпенсированная сердечная недостаточность; \u003Cbr /\u003E- желудочно-кишечные, цереброваскулярное или другие кровотечения (или подозрение на внутричерепное кровотечение); \u003Cbr /\u003E- почечная недостаточность тяжелой степени (клиренс креатинина менее 30 мл/мин), прогрессирующие заболевания почек; \u003Cbr /\u003E- печеночная недостаточность тяжелой степени (10-15 баллов по шкале Чайлд-Пью) или активное заболевание печени; \u003Cbr /\u003E- состояние после проведения аортокоронарного шунтирования; \u003Cbr /\u003E- подтверждённая гиперкалиемия; \u003Cbr /\u003E- детский возраст (до 18 лет); \u003Cbr /\u003E- хроническая диспепсия; \u003Cbr /\u003E- беременность III триместр; \u003Cbr /\u003E- период грудного вскармливания."},{"name":"Состав","value":"Действующее вещество: кетопрофен - 50 мг; \u003Cbr /\u003Eвспомогательные вещества: пропиленгликоль - 400 мг, этанол 96 % - 100 мг, бензиловый спирт - 20 мг, натрия гидроксид -для доведения рН 7,0 ± 0,5, вода для инъекций - до 1 мл."},{"name":"Действующее вещество","value":"Кетопрофен","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["27144131:28709512"]}}},{"name":"Способ применения и дозы","value":"Внутривенно, внутримышечно. \u003Cbr /\u003EВнутримышечное введение: по 100 мг (1 ампула) 1-2 раза в день. \u003Cbr /\u003EВнутривенное инфузионное введение кетопрофена должно проводиться только в условиях стационара. \u003Cbr /\u003EНепродолжительная внутривенная инфузия: 100-200 мг (1-2 ампулы) кетопрофена, разведенных в 100 мл 0,9% раствора натрия хлорида, вводится в течение 0,5-1 часа; возможно повторное введение через 8 часов. \u003Cbr /\u003EПродолжительная внутривенная инфузия: 100-200 мг (1-2 ампулы) кетопрофена, разведенных в 500 мл инфузионного раствора (0,9% раствор натрия хлорида, лактатсодержащий раствор Рингера, 5% раствор декстрозы), вводится в течение 8 часов; возможно повторное введение через 8 часов. \u003Cbr /\u003EКетопрофен можно сочетать с анальгетиками центрального действия; его можно смешивать с опиоидами (например, морфин) в одном флаконе, нельзя смешивать в одном флаконе с трамадолом из-за выпадения осадка. \u003Cbr /\u003EПарентеральное введение препарата можно сочетать с применением пероральных форм (таблетки, капсулы) или ректальных суппозиториев. \u003Cbr /\u003EПродолжительность терапии 48 часов (2 суток). \u003Cbr /\u003EМаксимальная доза кетопрофена составляет 200 мг/сутки."},{"name":"Побочные действия","value":"Побочные эффекты сгруппированы в соответствии с классификацией системноорганных классов MedDRA. Частота побочных эффектов приведена в соответствии с классификацией Всемирной организации здравоохранения (ВОЗ): очень часто (≥1/10), часто (≥1/100, \u003C1/10), нечасто (≥1/1000, \u003C1/100), редко (≥1/10000,\u003C1/1000), очень редко (\u003C10000) частота неизвестна (частоту возникновения явлений нельзя определить на основании имеющихся данных). \u003Cbr /\u003EНарушения со стороны крови и лимфатической системы: \u003Cbr /\u003EРедко: геморрагическая анемия, лейкопения; \u003Cbr /\u003EЧастота неизвестна: агранулоцитоз, тромбоцитопения, нарушение функции костного мозга. \u003Cbr /\u003EНарушения со стороны иммунной системы: \u003Cbr /\u003EЧастота неизвестна: анафилактические реакции (включая анафилактический шок). \u003Cbr /\u003EНарушения со стороны нервной системы: \u003Cbr /\u003EНечасто: головная боль, головокружение, сонливость; \u003Cbr /\u003EРедко: парестезии; \u003Cbr /\u003EЧастота неизвестна: судороги, нарушение вкусовых ощущений. \u003Cbr /\u003EНарушения со стороны органа зрения: \u003Cbr /\u003EРедко: нечеткость зрения; \u003Cbr /\u003EНарушения со стороны органа слуха и лабиринтные нарушения: \u003Cbr /\u003EРедко: шум в ушах. \u003Cbr /\u003EНарушения со стороны сердца: \u003Cbr /\u003EЧастота неизвестна: сердечная недостаточность, гипертония, вазодилатация. \u003Cbr /\u003EНарушения со стороны сосудов: \u003Cbr /\u003EЧастота неизвестна: гипертония, вазодилатация. \u003Cbr /\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: \u003Cbr /\u003EРедко: астма, носовые кровотечение, отек гортани; \u003Cbr /\u003EЧастота неизвестна: бронхоспазм (в особенности, у пациентов с гиперчувствительностью к НПВП), ринит. \u003Cbr /\u003EНарушения со стороны желудочно-кишечного тракта: \u003Cbr /\u003EЧасто: тошнота, рвота, диспепсия, боль в области живота; \u003Cbr /\u003EНечасто: запоры, диарея, вздутие живота, гастрит; \u003Cbr /\u003EРедко: пептическая язва, стоматит; \u003Cbr /\u003EОчень редко: обострение язвенного колита или болезни Крона, желудочно-кишечное кровотечение, перфорация. \u003Cbr /\u003EНарушения со стороны печени и желчевыводящих путей: \u003Cbr /\u003EРедко: гепатит, повышение уровня \"печеночных\" ферментов и билирубина. \u003Cbr /\u003EНарушения со стороны кожи и подкожных тканей: \u003Cbr /\u003EНечасто: кожная сыпь, кожный зуд; \u003Cbr /\u003EЧастота неизвестна: фотосенсибилизация, алопеция, крапивница, ангионевротический отек, эритема, буллезная сыпь, токсический эпидермальный некролиз. \u003Cbr /\u003EНарушения со стороны почек и мочевыводящих путей: \u003Cbr /\u003EОчень редко: острая почечная недостаточность, интерстициальный нефрит, нефротический синдром, аномальные значения показателей функции почек. \u003Cbr /\u003EОбщие нарушения и реакции в месте введения: \u003Cbr /\u003EНечасто: отеки, усталость; \u003Cbr /\u003EЧастота неизвестна: боль и ощущение жжения в месте введения, воспалительные реакции в месте введения."},{"name":"Фармакологическое действие","value":"Кетопрофен является нестероидным противовоспалительным препаратом, обладающим противовоспалительным, анальгезирующим и жаропонижающим действием. Благодаря ингибированию циклооксигеназ 1 и 2 и, частично, липооксигеназы, кетопрофен подавляет синтез простагландинов и брадикинина, стабилизирует лизосомальные мембраны. \u003Cbr /\u003EКетопрофен не оказывает отрицательного влияния на состояние суставного хряща."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763748"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. \u003Cbr /\u003EХранить в местах, недоступных для детей."},{"name":"Передозировка","value":"При передозировке кетопрофена могут отмечаться тошнота, рвота, боль в области живота, рвота с кровью, нарушение сознания, угнетение дыхания, судороги, нарушение функции почек и почечная недостаточность. \u003Cbr /\u003EПри передозировке показано промывание желудка и применение активированного угля. Лечение - симптоматическое; воздействие кетопрофена на желудочно-кишечный тракт можно ослабить с помощью ингибиторов протонной помпы и простагландинов. В случае развития почечной недостаточности рекомендуется проведение гемодиализа."},{"name":"Применение при беременности и кормлении грудью","value":"Кетопрофен ДС противопоказан к применению в в сроке более 20 недель беременности. В сроке до 20 недель беременности применение Кетопрофена ДС возможно в случаях, когда потенциальная польза для матери превышает потенциальный риск для плода, применять только под наблюдением врача. \u003Cbr /\u003EПри необходимости применения Кетопрофена ДС в период лактации грудное вскармливание рекомендуется прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения кетопрофеном возможно снижение скорости психических и двигательных реакций, поэтому необходимо воздерживаться от вождения транспорта и занятий другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью: \u003Cbr /\u003E - анемия; \u003Cbr /\u003E - бронхиальная астма; \u003Cbr /\u003E - алкоголизм; \u003Cbr /\u003E - табакокурение; \u003Cbr /\u003E - алкогольный цирроз печени; \u003Cbr /\u003E - гипербилирубинемия; \u003Cbr /\u003E - печеночная недостаточность; \u003Cbr /\u003E - дегидратация; \u003Cbr /\u003E - сепсис; \u003Cbr /\u003E - хроническая сердечная недостаточность (ХСН), отеки, артериальная гипертензия; \u003Cbr /\u003E - заболевания крови (в т.ч. лейкопения); \u003Cbr /\u003E - стоматит; \u003Cbr /\u003E - ишемическая болезнь сердца (ИБС); \u003Cbr /\u003E - цереброваскулярные заболевания; \u003Cbr /\u003E - дислипидемия/гиперлипидемия; \u003Cbr /\u003E - сахарный диабет; \u003Cbr /\u003E - заболевания периферических артерий; \u003Cbr /\u003E - хроническая почечная недостаточность (ХПН) (КК 30-60 мл/мин); \u003Cbr /\u003E - язвенные поражения желудочно-кишечного тракта (ЖКТ) в анамнезе, наличие инфекции Helicobacter pylori; \u003Cbr /\u003E - длительное применение НПВП; \u003Cbr /\u003E - тяжёлые соматические заболевания; \u003Cbr /\u003E - одновременное применение пероральных глюкокортикостероидных средств (ГКС) (в т.ч. преднизолона), антикоагулянтов (в т.ч. варфарина), антиагрегантов (в т.ч. клопидогрела), селективных ингибиторов обратного захвата серотонина (в т.ч. циталопрама, флуоксетина, пароксетина, сертралина); \u003Cbr /\u003E - пожилой возраст. \u003Cbr /\u003EПри длительном применении НПВП необходимо периодически оценивать клинический анализ крови, а также контролировать функцию печени и почек, в особенности, у пациентов пожилого возраста (старше 65 лет), проводить анализ кала на скрытую кровь. Необходимо соблюдать осторожность и чаще контролировать артериальное давление при применении кетопрофена для лечения пациентов, страдающих артериальной гипертензией, сердечно-сосудистыми заболеваниями, которые приводят к задержке жидкости в организме. \u003Cbr /\u003EПри возникновении нарушений со стороны органов зрения лечение следует незамедлительно прекратить. \u003Cbr /\u003EКак и другие НПВП, кетопрофен может маскировать симптомы инфекционно-воспалительных заболеваний. В случае обнаружения признаков инфекции или ухудшения самочувствия на фоне применения препарата необходима незамедлительно обратиться к врачу. \u003Cbr /\u003EПри наличии в анамнезе противопоказаний со стороны ЖКТ (кровотечения, перфорация, язвенная болезнь), проведении длительной терапии и применении высоких дозировок кетопрофена пациент должен находиться под тщательным наблюдением врача. \u003Cbr /\u003EИз-за важной роли простагландинов в поддержании почечного кровотока следует проявлять особую осторожность при назначении кетопрофена пациентам с сердечной или почечной недостаточностью, а также при лечении пожилых пациентов, принимающих диуретики, и пациентов, у которых, по какой-либо причине, наблюдается снижение объема циркулирующей крови (например, после хирургического вмешательства). Применение кетопрофена может влиять на женскую фертильность, поэтому пациенткам с бесплодием (в т.ч. проходящим обследование) не рекомендуется использовать препарат."},{"name":"Взаимодействие","value":"Кетопрофен может ослаблять действие диуретиков и гипотензивных средств и усиливать действие пероральных гипогликемических и некоторых противосудорожных препаратов (фенитоин). \u003Cbr /\u003EСовместное применение с другими НПВП, салицилатами, глюкокортикостероидами, этанолом повышает риск развития нежелательных явлений со стороны желудочно-кишечного тракта. \u003Cbr /\u003EОдновременное назначение с антикоагулянтами (гепарин, варфарин), тромболитиками, антиагрегантами (тиклопидин, клопидогрел) повышает риск развития кровотечений. \u003Cbr /\u003EОдновременное применение с калийсберегающими диуретиками, ингибиторами АПФ, НПВП, низкомолекулярными гепаринами, циклоспорином, такролимусом и триметопримом повышает риск развития гиперкалиемии. \u003Cbr /\u003EПовышает концентрацию в плазме крови сердечных гликозидов, блокаторов медленных кальциевых каналов, препаратов лития, циклоспорина, метотрексата и дигоксина. \u003Cbr /\u003EУвеличивает токсичность метотрексата и нефротоксичность циклоспорина. \u003Cbr /\u003EОдновременное использование с пробенецидом значительно снижает клиренс кетопрофена в плазме крови. \u003Cbr /\u003EСочетанный прием с глюкокортикоидами и другими НПВП (включая селективные ингибиторы ЦОГ2) увеличивает вероятность возникновения побочных эффектов (в частности, со стороны желудочно-кишечного тракта). \u003Cbr /\u003EНестероидные противоспалительные препараты могут уменьшать эффективность мифепристона. Прием НПВП следует начинать не ранее чем через 8-12 дней после отмены мифепристона."},{"name":"Регистрационный номер","value":"ЛП-003686"},{"name":"Дата государственной регистрации","value":"17.06.2021"},{"name":"Владелец регистрационного удостоверения","value":"ВетПром","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:16003523"]}}},{"name":"Страна бренда","value":"Болгария"},{"name":"Страна-производитель","value":"Болгария"},{"name":"Название препарата","value":"Кетопрофен","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:18025498"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"1964950738668806519":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"опорно-двигательная система"},{"name":"Назначение","value":"альгодисменорея, анкилозирующий спондилит, артрит, бурсит, невралгия, подагра, радикулит, тендинит, фибромиалгия"},{"name":"Показания к применению","value":"Препарат предназначен для симптоматической терапии, уменьшения боли и воспаления на момент использования, на прогрессирование заболевания не влияет. \u003Cbr /\u003EВоспалительные и дегенеративные заболевания опорно-двигательного аппарата: ревматоидный артрит, серонегативные артриты (анкилозирующий спондилит - болезнь Бехтерева, псориатрический артрит, реактивный артрит (синдром Рейтера)), подагра, псевдоподагра, остеоартроз. \u003Cbr /\u003EБолевой синдром: тендинит, бурсит, миалгия, невралгия, радикулит; головная боль; посттравматический и послеоперационный болевой синдром; болевой синдром при онкологических заболеваниях; альгодисменорея."},{"name":"Противопоказания","value":"- гиперчувствительность к кетопрофену или другим компонентам препарата, а также салицилатам или другим НПВП; \u003Cbr /\u003E- полное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе); \u003Cbr /\u003E- эрозивно-язвенные поражения желудочно-кишечного тракта и двенадцатиперстной кишки; \u003Cbr /\u003E- воспалительные заболевания кишечника (язвенный колит (обострение), болезнь Крона (обострение)); \u003Cbr /\u003E- гемофилия и другие нарушения свертываемости крови; \u003Cbr /\u003E- декомпенсированная сердечная недостаточность; \u003Cbr /\u003E- желудочно-кишечные, цереброваскулярное или другие кровотечения (или подозрение на внутричерепное кровотечение); \u003Cbr /\u003E- почечная недостаточность тяжелой степени (клиренс креатинина менее 30 мл/мин), прогрессирующие заболевания почек; \u003Cbr /\u003E- печеночная недостаточность тяжелой степени (10-15 баллов по шкале Чайлд-Пью) или активное заболевание печени; \u003Cbr /\u003E- состояние после проведения аортокоронарного шунтирования; \u003Cbr /\u003E- подтверждённая гиперкалиемия; \u003Cbr /\u003E- детский возраст (до 18 лет); \u003Cbr /\u003E- хроническая диспепсия; \u003Cbr /\u003E- беременность III триместр; \u003Cbr /\u003E- период грудного вскармливания."},{"name":"Состав","value":"Действующее вещество: кетопрофен - 50 мг; \u003Cbr /\u003Eвспомогательные вещества: пропиленгликоль - 400 мг, этанол 96 % - 100 мг, бензиловый спирт - 20 мг, натрия гидроксид -для доведения рН 7,0 ± 0,5, вода для инъекций - до 1 мл."},{"name":"Действующее вещество","value":"Кетопрофен"},{"name":"Способ применения и дозы","value":"Внутривенно, внутримышечно. \u003Cbr /\u003EВнутримышечное введение: по 100 мг (1 ампула) 1-2 раза в день. \u003Cbr /\u003EВнутривенное инфузионное введение кетопрофена должно проводиться только в условиях стационара. \u003Cbr /\u003EНепродолжительная внутривенная инфузия: 100-200 мг (1-2 ампулы) кетопрофена, разведенных в 100 мл 0,9% раствора натрия хлорида, вводится в течение 0,5-1 часа; возможно повторное введение через 8 часов. \u003Cbr /\u003EПродолжительная внутривенная инфузия: 100-200 мг (1-2 ампулы) кетопрофена, разведенных в 500 мл инфузионного раствора (0,9% раствор натрия хлорида, лактатсодержащий раствор Рингера, 5% раствор декстрозы), вводится в течение 8 часов; возможно повторное введение через 8 часов. \u003Cbr /\u003EКетопрофен можно сочетать с анальгетиками центрального действия; его можно смешивать с опиоидами (например, морфин) в одном флаконе, нельзя смешивать в одном флаконе с трамадолом из-за выпадения осадка. \u003Cbr /\u003EПарентеральное введение препарата можно сочетать с применением пероральных форм (таблетки, капсулы) или ректальных суппозиториев. \u003Cbr /\u003EПродолжительность терапии 48 часов (2 суток). \u003Cbr /\u003EМаксимальная доза кетопрофена составляет 200 мг/сутки."},{"name":"Побочные действия","value":"Побочные эффекты сгруппированы в соответствии с классификацией системноорганных классов MedDRA. Частота побочных эффектов приведена в соответствии с классификацией Всемирной организации здравоохранения (ВОЗ): очень часто (≥1/10), часто (≥1/100, \u003C1/10), нечасто (≥1/1000, \u003C1/100), редко (≥1/10000,\u003C1/1000), очень редко (\u003C10000) частота неизвестна (частоту возникновения явлений нельзя определить на основании имеющихся данных). \u003Cbr /\u003EНарушения со стороны крови и лимфатической системы: \u003Cbr /\u003EРедко: геморрагическая анемия, лейкопения; \u003Cbr /\u003EЧастота неизвестна: агранулоцитоз, тромбоцитопения, нарушение функции костного мозга. \u003Cbr /\u003EНарушения со стороны иммунной системы: \u003Cbr /\u003EЧастота неизвестна: анафилактические реакции (включая анафилактический шок). \u003Cbr /\u003EНарушения со стороны нервной системы: \u003Cbr /\u003EНечасто: головная боль, головокружение, сонливость; \u003Cbr /\u003EРедко: парестезии; \u003Cbr /\u003EЧастота неизвестна: судороги, нарушение вкусовых ощущений. \u003Cbr /\u003EНарушения со стороны органа зрения: \u003Cbr /\u003EРедко: нечеткость зрения; \u003Cbr /\u003EНарушения со стороны органа слуха и лабиринтные нарушения: \u003Cbr /\u003EРедко: шум в ушах. \u003Cbr /\u003EНарушения со стороны сердца: \u003Cbr /\u003EЧастота неизвестна: сердечная недостаточность, гипертония, вазодилатация. \u003Cbr /\u003EНарушения со стороны сосудов: \u003Cbr /\u003EЧастота неизвестна: гипертония, вазодилатация. \u003Cbr /\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: \u003Cbr /\u003EРедко: астма, носовые кровотечение, отек гортани; \u003Cbr /\u003EЧастота неизвестна: бронхоспазм (в особенности, у пациентов с гиперчувствительностью к НПВП), ринит. \u003Cbr /\u003EНарушения со стороны желудочно-кишечного тракта: \u003Cbr /\u003EЧасто: тошнота, рвота, диспепсия, боль в области живота; \u003Cbr /\u003EНечасто: запоры, диарея, вздутие живота, гастрит; \u003Cbr /\u003EРедко: пептическая язва, стоматит; \u003Cbr /\u003EОчень редко: обострение язвенного колита или болезни Крона, желудочно-кишечное кровотечение, перфорация. \u003Cbr /\u003EНарушения со стороны печени и желчевыводящих путей: \u003Cbr /\u003EРедко: гепатит, повышение уровня \"печеночных\" ферментов и билирубина. \u003Cbr /\u003EНарушения со стороны кожи и подкожных тканей: \u003Cbr /\u003EНечасто: кожная сыпь, кожный зуд; \u003Cbr /\u003EЧастота неизвестна: фотосенсибилизация, алопеция, крапивница, ангионевротический отек, эритема, буллезная сыпь, токсический эпидермальный некролиз. \u003Cbr /\u003EНарушения со стороны почек и мочевыводящих путей: \u003Cbr /\u003EОчень редко: острая почечная недостаточность, интерстициальный нефрит, нефротический синдром, аномальные значения показателей функции почек. \u003Cbr /\u003EОбщие нарушения и реакции в месте введения: \u003Cbr /\u003EНечасто: отеки, усталость; \u003Cbr /\u003EЧастота неизвестна: боль и ощущение жжения в месте введения, воспалительные реакции в месте введения."},{"name":"Фармакологическое действие","value":"Кетопрофен является нестероидным противовоспалительным препаратом, обладающим противовоспалительным, анальгезирующим и жаропонижающим действием. Благодаря ингибированию циклооксигеназ 1 и 2 и, частично, липооксигеназы, кетопрофен подавляет синтез простагландинов и брадикинина, стабилизирует лизосомальные мембраны. \u003Cbr /\u003EКетопрофен не оказывает отрицательного влияния на состояние суставного хряща."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. \u003Cbr /\u003EХранить в местах, недоступных для детей."},{"name":"Передозировка","value":"При передозировке кетопрофена могут отмечаться тошнота, рвота, боль в области живота, рвота с кровью, нарушение сознания, угнетение дыхания, судороги, нарушение функции почек и почечная недостаточность. \u003Cbr /\u003EПри передозировке показано промывание желудка и применение активированного угля. Лечение - симптоматическое; воздействие кетопрофена на желудочно-кишечный тракт можно ослабить с помощью ингибиторов протонной помпы и простагландинов. В случае развития почечной недостаточности рекомендуется проведение гемодиализа."},{"name":"Применение при беременности и кормлении грудью","value":"Кетопрофен ДС противопоказан к применению в в сроке более 20 недель беременности. В сроке до 20 недель беременности применение Кетопрофена ДС возможно в случаях, когда потенциальная польза для матери превышает потенциальный риск для плода, применять только под наблюдением врача. \u003Cbr /\u003EПри необходимости применения Кетопрофена ДС в период лактации грудное вскармливание рекомендуется прекратить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения кетопрофеном возможно снижение скорости психических и двигательных реакций, поэтому необходимо воздерживаться от вождения транспорта и занятий другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью: \u003Cbr /\u003E - анемия; \u003Cbr /\u003E - бронхиальная астма; \u003Cbr /\u003E - алкоголизм; \u003Cbr /\u003E - табакокурение; \u003Cbr /\u003E - алкогольный цирроз печени; \u003Cbr /\u003E - гипербилирубинемия; \u003Cbr /\u003E - печеночная недостаточность; \u003Cbr /\u003E - дегидратация; \u003Cbr /\u003E - сепсис; \u003Cbr /\u003E - хроническая сердечная недостаточность (ХСН), отеки, артериальная гипертензия; \u003Cbr /\u003E - заболевания крови (в т.ч. лейкопения); \u003Cbr /\u003E - стоматит; \u003Cbr /\u003E - ишемическая болезнь сердца (ИБС); \u003Cbr /\u003E - цереброваскулярные заболевания; \u003Cbr /\u003E - дислипидемия/гиперлипидемия; \u003Cbr /\u003E - сахарный диабет; \u003Cbr /\u003E - заболевания периферических артерий; \u003Cbr /\u003E - хроническая почечная недостаточность (ХПН) (КК 30-60 мл/мин); \u003Cbr /\u003E - язвенные поражения желудочно-кишечного тракта (ЖКТ) в анамнезе, наличие инфекции Helicobacter pylori; \u003Cbr /\u003E - длительное применение НПВП; \u003Cbr /\u003E - тяжёлые соматические заболевания; \u003Cbr /\u003E - одновременное применение пероральных глюкокортикостероидных средств (ГКС) (в т.ч. преднизолона), антикоагулянтов (в т.ч. варфарина), антиагрегантов (в т.ч. клопидогрела), селективных ингибиторов обратного захвата серотонина (в т.ч. циталопрама, флуоксетина, пароксетина, сертралина); \u003Cbr /\u003E - пожилой возраст. \u003Cbr /\u003EПри длительном применении НПВП необходимо периодически оценивать клинический анализ крови, а также контролировать функцию печени и почек, в особенности, у пациентов пожилого возраста (старше 65 лет), проводить анализ кала на скрытую кровь. Необходимо соблюдать осторожность и чаще контролировать артериальное давление при применении кетопрофена для лечения пациентов, страдающих артериальной гипертензией, сердечно-сосудистыми заболеваниями, которые приводят к задержке жидкости в организме. \u003Cbr /\u003EПри возникновении нарушений со стороны органов зрения лечение следует незамедлительно прекратить. \u003Cbr /\u003EКак и другие НПВП, кетопрофен может маскировать симптомы инфекционно-воспалительных заболеваний. В случае обнаружения признаков инфекции или ухудшения самочувствия на фоне применения препарата необходима незамедлительно обратиться к врачу. \u003Cbr /\u003EПри наличии в анамнезе противопоказаний со стороны ЖКТ (кровотечения, перфорация, язвенная болезнь), проведении длительной терапии и применении высоких дозировок кетопрофена пациент должен находиться под тщательным наблюдением врача. \u003Cbr /\u003EИз-за важной роли простагландинов в поддержании почечного кровотока следует проявлять особую осторожность при назначении кетопрофена пациентам с сердечной или почечной недостаточностью, а также при лечении пожилых пациентов, принимающих диуретики, и пациентов, у которых, по какой-либо причине, наблюдается снижение объема циркулирующей крови (например, после хирургического вмешательства). Применение кетопрофена может влиять на женскую фертильность, поэтому пациенткам с бесплодием (в т.ч. проходящим обследование) не рекомендуется использовать препарат."},{"name":"Взаимодействие","value":"Кетопрофен может ослаблять действие диуретиков и гипотензивных средств и усиливать действие пероральных гипогликемических и некоторых противосудорожных препаратов (фенитоин). \u003Cbr /\u003EСовместное применение с другими НПВП, салицилатами, глюкокортикостероидами, этанолом повышает риск развития нежелательных явлений со стороны желудочно-кишечного тракта. \u003Cbr /\u003EОдновременное назначение с антикоагулянтами (гепарин, варфарин), тромболитиками, антиагрегантами (тиклопидин, клопидогрел) повышает риск развития кровотечений. \u003Cbr /\u003EОдновременное применение с калийсберегающими диуретиками, ингибиторами АПФ, НПВП, низкомолекулярными гепаринами, циклоспорином, такролимусом и триметопримом повышает риск развития гиперкалиемии. \u003Cbr /\u003EПовышает концентрацию в плазме крови сердечных гликозидов, блокаторов медленных кальциевых каналов, препаратов лития, циклоспорина, метотрексата и дигоксина. \u003Cbr /\u003EУвеличивает токсичность метотрексата и нефротоксичность циклоспорина. \u003Cbr /\u003EОдновременное использование с пробенецидом значительно снижает клиренс кетопрофена в плазме крови. \u003Cbr /\u003EСочетанный прием с глюкокортикоидами и другими НПВП (включая селективные ингибиторы ЦОГ2) увеличивает вероятность возникновения побочных эффектов (в частности, со стороны желудочно-кишечного тракта). \u003Cbr /\u003EНестероидные противоспалительные препараты могут уменьшать эффективность мифепристона. Прием НПВП следует начинать не ранее чем через 8-12 дней после отмены мифепристона."},{"name":"Регистрационный номер","value":"ЛП-003686"},{"name":"Дата государственной регистрации","value":"17.06.2021"},{"name":"Владелец регистрационного удостоверения","value":"ВетПром"},{"name":"Страна бренда","value":"Болгария"},{"name":"Страна-производитель","value":"Болгария"},{"name":"Название препарата","value":"Кетопрофен"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_12868406531928052817"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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    Цена 98 ₽
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  • Кетопрофен р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.
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    Кетопрофен р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 4.7 из 5
    на основе 13 оценок
    Цена 104 ₽
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  • Кетопрофен р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6j78jznyzk9/toggleWishlist":{"skuId":"101392427751","productId":526944146,"offerId":"XGIWnc4ZK_JnnbSeItt57g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ89aSzs3w5IsMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIko+i+wEQ59XW2/kCGISpsggg59zBBw==","sign":"DnRfoaydVqezhEYZ0y804FV7CKB8B3W9Nc8sl6BNvVk="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6j78jznyzk9/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Кетопрофен р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 207 ₽
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  • Кетопрофен-Солофарм р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xpk3vx3qz6g/toggleWishlist":{"skuId":"667636003","productId":1778170734,"offerId":"8zxZa8XN03B8uf0iOrkBKA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ89aSzs3w5IsMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI7vbyzwYQo6KtvgIYh97QByDn3MEH","sign":"RfgS6kGfLZyfnaXnIF761yC6YdTfhKekqZd+crfnPj4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xpk3vx3qz6g/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Кетопрофен-Солофарм р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 210 ₽
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  • Кетопрофен р-р для в/в и в/м введ., 50 мг/мл, 2 мл, 10 шт.
    –29 %
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    Кетопрофен р-р для в/в и в/м введ., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 123 ₽ вместо 173
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  • Кетопрофен-АКОС р-р для в/в введ. и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6krgx0tcvl/toggleWishlist":{"skuId":"101392529736","productId":186858050,"offerId":"M1sDdMYQVeiWiLSim8ecqA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ89aSzs3w5IsMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIwvSMWRDI8tzb+QIYsc2dBSDn3MEH","sign":"rXTkgYslxXwXZjE7rE9FiAITgKyrWT7F1wIdD3Etd7c="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6krgx0tcvl/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Кетопрофен-АКОС р-р для в/в введ. и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 4.3 из 5
    на основе 6 оценок
    Цена 234 ₽
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  • Кетопрофен таб. п/о плен., 100 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9y8rygvh9t/toggleWishlist":{"skuId":"101476674001","productId":1460347365,"offerId":"hB6zJ-kPQHK2LVfx7UK-Wg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ89aSzs3w5IsMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI5cOsuAUQ0dPsg/oCGJXd0Acg59zBBw==","sign":"fCRvHU0OednbIX/PW/o+oZ6QMErlzkt+JyzkQQMZrYw="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9y8rygvh9t/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Кетопрофен таб. п/о плен., 100 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 7 оценок
    Цена 128 ₽
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  • Мелоксикам р-р для в/м введ., 10 мг/мл, 1.5 мл, 5 шт.
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    Мелоксикам р-р для в/м введ., 10 мг/мл, 1.5 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 5 оценок
    Цена 265 ₽
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  • Кетонал р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hsd2tj7e6zg/toggleWishlist":{"skuId":"667778002","productId":1422663522,"offerId":"2l8YBbunnnsp1o12RD5zbA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ89aSzs3w5IsMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI4r6wpgUQ0ve1vgIYxJzQByDn3MEH","sign":"NAyR6dVoofKzpzuz9RQNzLpJEMR224bXDXae2YbeIpw="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hsd2tj7e6zg/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Кетонал р-р для в/в и в/м введ. амп., 50 мг/мл, 2 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 131 ₽
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  • Кетопрофен таб., 100 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qljla745jv/toggleWishlist":{"skuId":"648953034","productId":1778175004,"offerId":"i4vYmtj6FY5KzG5Iyvg5ww","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ89aSzs3w5IsMEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYInJjzzwYQyvm4tQIYtNWHBCDn3MEH","sign":"TeVeet/m9xYS4vYpMvswKW2iJG2vkNBvGq2GsTiUIls="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qljla745jv/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Кетопрофен таб., 100 мг, 20 шт.

    Рейтинг товара: 4.6 из 5
    на основе 14 оценок
    Цена 125 ₽
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  • Аркетал Ромфарм р-р д/инф. и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.
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    Аркетал Ромфарм р-р д/инф. и в/м введ. амп., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 219 ₽
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  • Кетопрофен органика таб. п/о плен., 100 мг, 20 шт.
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    Кетопрофен органика таб. п/о плен., 100 мг, 20 шт.

    Рейтинг товара: 4.2 из 5
    на основе 11 оценок
    Цена 143 ₽
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Инструкция

Показания к применению

Препарат предназначен для симптоматической терапии, уменьшения боли и воспаления на момент использования, на прогрессирование заболевания не влияет.
Воспалительные и дегенеративные заболевания опорно-двигательного аппарата: ревматоидный артрит, серонегативные артриты (анкилозирующий спондилит - болезнь Бехтерева, псориатрический артрит, реактивный артрит (синдром Рейтера)), подагра, псевдоподагра, остеоартроз.
Болевой синдром: тендинит, бурсит, миалгия, невралгия, радикулит; головная боль; посттравматический и послеоперационный болевой синдром; болевой синдром при онкологических заболеваниях; альгодисменорея.

Противопоказания

- гиперчувствительность к кетопрофену или другим компонентам препарата, а также салицилатам или другим НПВП;
- полное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе);
- эрозивно-язвенные поражения желудочно-кишечного тракта и двенадцатиперстной кишки;
- воспалительные заболевания кишечника (язвенный колит (обострение), болезнь Крона (обострение));
- гемофилия и другие нарушения свертываемости крови;
- декомпенсированная сердечная недостаточность;
- желудочно-кишечные, цереброваскулярное или другие кровотечения (или подозрение на внутричерепное кровотечение);
- почечная недостаточность тяжелой степени (клиренс креатинина менее 30 мл/мин), прогрессирующие заболевания почек;
- печеночная недостаточность тяжелой степени (10-15 баллов по шкале Чайлд-Пью) или активное заболевание печени;
- состояние после проведения аортокоронарного шунтирования;
- подтверждённая гиперкалиемия;
- детский возраст (до 18 лет);
- хроническая диспепсия;
- беременность III триместр;
- период грудного вскармливания.

Способ применения и дозы

Внутривенно, внутримышечно.
Внутримышечное введение: по 100 мг (1 ампула) 1-2 раза в день.
Внутривенное инфузионное введение кетопрофена должно проводиться только в условиях стационара.
Непродолжительная внутривенная инфузия: 100-200 мг (1-2 ампулы) кетопрофена, разведенных в 100 мл 0,9% раствора натрия хлорида, вводится в течение 0,5-1 часа; возможно повторное введение через 8 часов.
Продолжительная внутривенная инфузия: 100-200 мг (1-2 ампулы) кетопрофена, разведенных в 500 мл инфузионного раствора (0,9% раствор натрия хлорида, лактатсодержащий раствор Рингера, 5% раствор декстрозы), вводится в течение 8 часов; возможно повторное введение через 8 часов.
Кетопрофен можно сочетать с анальгетиками центрального действия; его можно смешивать с опиоидами (например, морфин) в одном флаконе, нельзя смешивать в одном флаконе с трамадолом из-за выпадения осадка.
Парентеральное введение препарата можно сочетать с применением пероральных форм (таблетки, капсулы) или ректальных суппозиториев.
Продолжительность терапии 48 часов (2 суток).
Максимальная доза кетопрофена составляет 200 мг/сутки.
Полная инструкция
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Кетопрофен ДС р-р для в/в введ. и в/м введ.
Кетопрофен ДС р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 5 шт.
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Инструкция

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