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Описание

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Клиндацин Б пролонг крем ваг., 20 г, 1 шт.

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5.0
(2)
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Коротко о товаре

Артикул Маркета
3123922210
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"1559074394253480114":{"specItems":[{"name":"Артикул Маркета","value":"3123922210","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"бактериальный вагиноз, вагинит","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["36476390:36618445,36617698"]}}},{"name":"действующее вещество","value":"Бутоконазол+Клиндамицин","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27144131:36090362"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"крем"},{"name":"способ применения/введения","value":"интравагинально, местный","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["35947170:36763743,36763736"]}}},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"1559074394253480114":{"specItems":[{"name":"Артикул Маркета","value":"3123922210","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Назначение","value":"Бактериальный вагиноз, вагинит","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["36476390:36618445,36617698"]}}},{"name":"Действующее вещество","value":"Бутоконазол+Клиндамицин","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27144131:36090362"]}}},{"name":"Возраст","value":"От 18 лет"}]}},"fullSpecs":{"1559074394253480114":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"половая система"},{"name":"Назначение","value":"бактериальный вагиноз, вагинит","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["36476390:36618445,36617698"]}}},{"name":"Показания к применению","value":"Бактериальные вагинозы, грибковые и смешанные вагиниты, вызванные чувствительными к лекарственному средству микроорганизмами."},{"name":"Противопоказания","value":"Повышенная чувствительность к клиндамицину, линкомицину, бутоконазолу или любому компоненту препарата; воспалительные заболевания кишечника (болезнь Крона, язвенный, псевдомембранозный и антибиотик-ассоциированный колиты (в том числе в анамнезе)); детский возраст до 18 лет."},{"name":"Состав","value":"100 г крема содержат:\u003Cbr\u003Eдействующие вещества: бутоконазола нитрат в пересчете на 100 % вещество - 2 г; клинда¬мицина фосфат в пересчете на 100 % вещество - 2,376 г, что эквивалентно 2 г клиндамици¬на;\u003Cbr\u003Eвспомогательные вещества: консервант Euxyl РЕ 9010 (феноксиэтанол 90 %, этилгексилглицерол 10 %) 0,5 г, что эквивалентно 0.45 г феноксиэтанола, пропиленгликоль 5 г, изопропилмиристат 8 г, макрогола цетостеарат (макрогола-20 цетостеариловый эфир) 2 г, цетостеариловый спирт [цетиловый спирт 60 %, стеариловый спирт 40 %] 6 г, гидроксипропилдикрахмалфосфат 8 г, натрия гидроксид 0,26 г, вода очищенная до 100 г."},{"name":"Действующее вещество","value":"Бутоконазол+Клиндамицин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27144131:36090362"]}}},{"name":"Способ применения и дозы","value":"Вводится интравагинально с помощью аппликатора. Применяется 1 раз в день, предпочтительно перед сном. Рекомендуемая доза составляет один полный аппликатор (5 г крема, что соответствует 100 мг бутоконазола нитрата и 100 мг клиндамицина). Курс лечения - ежедневно в течение 3-х дней.\u003Cbr\u003EИнструкция по использованию аппликатора\u003Cbr\u003EОдноразовые аппликаторы, прилагающиеся к упаковке, предназначены для точного дозирования и введения крема Клиндаци Б пролонг во влагалище.\u003Cbr\u003E1. Откройте тубу с кремом, сняв колпачок. Проколите мембрану тубы обратной стороной колпачка. Навинтите пластмассовый аппликатор на снабженное резьбой горлышко тюбика.\u003Cbr\u003E2. Мягко надавливая на тубу с противоположного конца, осторожно выдавите крем в аппликатор. Поршень аппликатора двигается самостоятельно по мере заполнения необходимого объема. Аппликатор заполнен, когда поршень доходит до упора. Отвинтите аппликатор и закройте тубу колпачком\u003Cbr\u003E3. В положении лежа на спине подтяните колени к груди. Держа аппликатор горизонтально, осторожно введите его во влагалище как можно глубже, стараясь не вызвать неприятных ощущений.\u003Cbr\u003E4. Медленно надавливая на поршень до упора, введите весь объем крема во влагалище.\u003Cbr\u003E5. Осторожно извлеките аппликатор из влагалища и выбросите его в мусорный контейнер."},{"name":"Побочные действия","value":"Безопасность вагинального крема клиндамицина оценивали как у небеременных пациенток, так и у пациенток во II и III триместрах беременности. Нежелательные лекарственные реакции, зарегистрированные при применении клиндамицина, крема вагинального. Определение частоты нежелательных реакций: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10 000 до \u003C1/1000), очень редко (\u003C1/10 000), частота неизвестна (невозможно оценить на основании имеющихся данных). \u003Cbr\u003EИнфекционные и паразитарные заболевания: часто - грибковые инфекции, вызываемые грибами рода Candida; нечасто - бактериальные инфекции; частота неизвестна - кандидоз кожи.\u003Cbr\u003EСо стороны иммунной системы: нечасто - гиперчувствительность.\u003Cbr\u003EСо стороны эндокринной системы: частота неизвестна - гипертиреоз.\u003Cbr\u003EСо стороны нервной системы: часто - головная боль, головокружение, дисгевзия.\u003Cbr\u003EСо стороны органа слуха и вестибулярного аппарата: нечасто - вертиго.\u003Cbr\u003EСо стороны дыхательной системы: часто - инфекции верхних дыхательных путей; нечасто - носовое кровотечение.\u003Cbr\u003EСо стороны пищеварительной системы: часто - боль в животе, запор, диарея, тошнота, рвота; нечасто - вздутие живота, метеоризм, неприятный запах изо рта; частота неизвестна - псевдомембранозный колит*, желудочно-кишечные расстройства, диспепсия.\u003Cbr\u003EСо стороны кожи и подкожных тканей: часто - зуд кожи, сыпь; нечасто - крапивница, эритема; частота неизвестна - макуло-папулезная сыпь.\u003Cbr\u003EСо стороны костно-мышечной системы: часто - боль в спине.\u003Cbr\u003EСо стороны мочевыделительной системы: часто - инфекции мочевыводящих путей, глюкозурия, протеинурия; нечасто - дизурия.\u003Cbr\u003EБеременность, послеродовые и перинатальные состояния: часто - аномальные роды.\u003Cbr\u003EСо стороны половых органов и молочной железы: очень часто - вульвовагинальный кандидоз; часто - вульвовагинит, вульвовагинальные расстройства, нарушение менструального цикла, вульвовагинальная боль, метроррагия, выделения из влагалища; нечасто - трихомонадный вульвовагинит, вагинальные инфекции, боль в тазу; частота неизвестна - эндометриоз.\u003Cbr\u003EОбщие расстройства и реакции в месте в ведения: частота неизвестна - воспаление, боль.\u003Cbr\u003EДанные лабораторных и инструментальных исследований: нечасто - отклонение результатов микробиологических анализов от нормы.\u003Cbr\u003E* Нежелательные лекарственные реакции, выявленные в пострегистрационном периоде."},{"name":"Фармакологическое действие","value":"Бутоконазол - производное имидазола, обладает фунгицидной активностью в отношении грибов Candida, Trichophyton, Microsporum, Epidermaphyton и некоторых грамположительных бактерий. Наиболее эффективен при кандидозах.\u003Cbr\u003EБлокируя в клеточной мембране образование эргостерола из ланостерола, увеличивает проницаемость мембраны, что приводит к лизису клетки гриба. Клиндамицин - бактериостатический антибиотик из группы линкозамидов, обладает широким спектром действия, связывается с 50S субъединицей рибосомальной мембраны и подавляет синтез белка в микробной клетке. В отношении ряда грамположительных кокков возможно бактерицидное действие.\u003Cbr\u003EВ условиях in vitro к клиндамицину чувствительны следующие микроорганизмы, вызывающие бактериальные вагинозы: Gardnerella vaginalis, Mobiluncus spp., Mycoplasma hominis, Bacteroides spp., Peptostreptococcus spp.\u003Cbr\u003EГидрофильная кремовая основа обеспечивает препарату гелеобразную консистенцию при температуре 35-40 °С. При интравагинальном применении крем не плавится, в связи с чем активные вещества находятся на слизистой оболочке влагалища в течение 1-3 дней.\u003Cbr\u003EСуществует перекрестная резистентность между клиндамицином и линкомицином."},{"name":"Фармакологическая группа","value":"противомикробное и противогрибковое средство"},{"name":"Форма выпуска","value":"крем"},{"name":"Способ применения/введения","value":"интравагинально, местный","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["35947170:36763743,36763736"]}}},{"name":"Пол","value":"для женщин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["14805991:14805993"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре от 15 до 25 °C. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При интравагинальном применении препарата передозировка не установлена. Возможна абсорбция клиндамицина в количествах, достаточных для развития системных реакций.\u003Cbr\u003EСлучайное попадание препарата в желудочно-кишечный тракт также может вызвать системные эффекты, сходные с теми, который возникают после приема внутрь клиндамицина в терапевтических дозах. К возможным системным побочным эффектам можно отнести диарею, геморрагическую диарею, включая псевдомембранозный колит (см. разделы \"Побочное действие\" и \"Особые указания\"). Лечение: симптоматическое и поддерживающее."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата в период беременности и лактации возможно только в том случае, если потенциальная польза для матери превышает риск для плода или ребенка.\u003Cbr\u003EАдекватных контролируемых исследований по применению препарата в I триместре беременности не проводилось, поэтому Клиндацин Б пролонг можно назначать женщинам в I триместре беременности только по абсолютным показаниям, т.е. когда потенциальная польза терапии препаратом для матери превосходит потенциальный риск для плода. В исследованиях на животных при введении клиндамицина подкожно или внутрь каких-либо отрицательных влияний на плод не обнаружено, за исключением случаев приема препарата в дозах, токсичных для матери. При применении клиндамицина интравагинально во II или III триместре беременности увеличения частоты врожденных аномалий плода не отмечалось. Аномальные роды имели место у 1,1% женщин по сравнению с 0,5% в группе плацебо, если клиндамицин крем вагинальный применялся во II триместре в течение 7 дней. Применение препарата во П-Ш триместре беременности возможно, если потенциальная польза для матери превосходит риск для плода.\u003Cbr\u003EНеизвестно, выделяется ли клиндамицин в грудное молоко после интравагинального применения. Клиндамицин обнаружен в грудном молоке после перорального или парентерального введения, поэтому в период грудного вскармливания следует либо отменить применение препарата, либо прекратить грудное вскармливание, учитывая степень важности применения препарата для матери."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Нет оснований полагать, что применение препарата Клиндацин Б Пролонг крем вагинальный может оказывать влияние на способность к вождению автомобиля и управлению механизмами."},{"name":"Особые указания","value":"До назначения препарата с помощью соответствующих лабораторных методов должны быть исключены Trichomonas vaginalis, Chlamidia trachomatis, Neisseria gonorrhoeae и Herpes simplex virus, часто вызывающие вульвовагинит.\u003Cbr\u003E\n\u003Cbr\u003EИнтравагинальное применение клиндамицина может привести к усиленному росту нечувствительных микроорганизмов, особенно дрожжеподобных грибов.\u003Cbr\u003E\n\u003Cbr\u003EПрименение клиндамицина (как и практически всех антибиотиков) внутрь или парентерально связано с развитием тяжелой диареи и в ряде случаев псевдомембранозного колита. При развитии выраженной или длительной диареи препарат следует отменить и при необходимости провести соответствующее диагностические и лечебные мероприятия.\u003Cbr\u003E\u003Cbr\u003EПациентов следует предупредить о том, что во время терапии препаратом не следует вступать в половые сношения.\u003Cbr\u003E\u003Cbr\u003EВагинальный крем не рекомендуется использовать одновременно с другими интраваги- нальными лекарственными средствами.\u003Cbr\u003E\u003Cbr\u003EНе рекомендуется применение препарата в период менструации. Следует отложить начало терапии до окончания менструации.\u003Cbr\u003E\u003Cbr\u003EПрепарат содержит компоненты, которые могут уменьшить прочность изделий из латекса или каучука, поэтому использование презервативов, влагалищных противозачаточных диафрагм и других средств из латекса для интравагинального применения во время терапии препаратом и в течение 72 часов после применения не рекомендуется.\u003Cbr\u003E\u003Cbr\u003EЕсли клинические признаки инфекции сохраняются после завершения лечения, следует провести повторное микробиологическое исследование для выявления возбудителя и подтверждения диагноза.\u003Cbr\u003E\u003Cbr\u003EВходящий в состав препарата цетостеариловый спирт может вызвать местные кожные реакции (сыпь, контактный дерматит). Появление раздражения слизистой оболочки влагалища или болезненных ощущений, служит показанием к прекращению лечения."},{"name":"Взаимодействие","value":"Существует перекрестная резистентность между клиндамицином и линкомицином. В условиях in vitro продемонстрирован анатагонизм между клиндамицином и эритромицином. Установлено, что клиндамицин при системном применении нарушает нейромышечную передачу и, следовательно, может усиливать действие миорелаксантов периферического действия, поэтому препарат следует применять с осторожностью у больных, получающих препараты данной группы. Совместное применение с другими препаратами для интравагиналыюго введения не рекомендуется. Несовместим с растворами, содержащими комплекс витаминов группы В, аминогликозидами, ампициллином, кальция глюконатом и магния сульфатом."},{"name":"Регистрационный номер","value":"ЛП-001855"},{"name":"Дата государственной регистрации","value":"22.06.2022"},{"name":"Владелец регистрационного удостоверения","value":"АКРИХИН","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["34324371:35649313","7893318:11037214"]}}},{"name":"Изготовитель","value":"АКРИХИН"},{"name":"Фасовщик","value":"АКРИХИН"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Клиндацин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["17796364:18037413"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"1559074394253480114":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"половая система"},{"name":"Назначение","value":"бактериальный вагиноз, вагинит"},{"name":"Показания к применению","value":"Бактериальные вагинозы, грибковые и смешанные вагиниты, вызванные чувствительными к лекарственному средству микроорганизмами."},{"name":"Противопоказания","value":"Повышенная чувствительность к клиндамицину, линкомицину, бутоконазолу или любому компоненту препарата; воспалительные заболевания кишечника (болезнь Крона, язвенный, псевдомембранозный и антибиотик-ассоциированный колиты (в том числе в анамнезе)); детский возраст до 18 лет."},{"name":"Состав","value":"100 г крема содержат:\u003Cbr\u003Eдействующие вещества: бутоконазола нитрат в пересчете на 100 % вещество - 2 г; клинда¬мицина фосфат в пересчете на 100 % вещество - 2,376 г, что эквивалентно 2 г клиндамици¬на;\u003Cbr\u003Eвспомогательные вещества: консервант Euxyl РЕ 9010 (феноксиэтанол 90 %, этилгексилглицерол 10 %) 0,5 г, что эквивалентно 0.45 г феноксиэтанола, пропиленгликоль 5 г, изопропилмиристат 8 г, макрогола цетостеарат (макрогола-20 цетостеариловый эфир) 2 г, цетостеариловый спирт [цетиловый спирт 60 %, стеариловый спирт 40 %] 6 г, гидроксипропилдикрахмалфосфат 8 г, натрия гидроксид 0,26 г, вода очищенная до 100 г."},{"name":"Действующее вещество","value":"Бутоконазол+Клиндамицин"},{"name":"Способ применения и дозы","value":"Вводится интравагинально с помощью аппликатора. Применяется 1 раз в день, предпочтительно перед сном. Рекомендуемая доза составляет один полный аппликатор (5 г крема, что соответствует 100 мг бутоконазола нитрата и 100 мг клиндамицина). Курс лечения - ежедневно в течение 3-х дней.\u003Cbr\u003EИнструкция по использованию аппликатора\u003Cbr\u003EОдноразовые аппликаторы, прилагающиеся к упаковке, предназначены для точного дозирования и введения крема Клиндаци Б пролонг во влагалище.\u003Cbr\u003E1. Откройте тубу с кремом, сняв колпачок. Проколите мембрану тубы обратной стороной колпачка. Навинтите пластмассовый аппликатор на снабженное резьбой горлышко тюбика.\u003Cbr\u003E2. Мягко надавливая на тубу с противоположного конца, осторожно выдавите крем в аппликатор. Поршень аппликатора двигается самостоятельно по мере заполнения необходимого объема. Аппликатор заполнен, когда поршень доходит до упора. Отвинтите аппликатор и закройте тубу колпачком\u003Cbr\u003E3. В положении лежа на спине подтяните колени к груди. Держа аппликатор горизонтально, осторожно введите его во влагалище как можно глубже, стараясь не вызвать неприятных ощущений.\u003Cbr\u003E4. Медленно надавливая на поршень до упора, введите весь объем крема во влагалище.\u003Cbr\u003E5. Осторожно извлеките аппликатор из влагалища и выбросите его в мусорный контейнер."},{"name":"Побочные действия","value":"Безопасность вагинального крема клиндамицина оценивали как у небеременных пациенток, так и у пациенток во II и III триместрах беременности. Нежелательные лекарственные реакции, зарегистрированные при применении клиндамицина, крема вагинального. Определение частоты нежелательных реакций: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10 000 до \u003C1/1000), очень редко (\u003C1/10 000), частота неизвестна (невозможно оценить на основании имеющихся данных). \u003Cbr\u003EИнфекционные и паразитарные заболевания: часто - грибковые инфекции, вызываемые грибами рода Candida; нечасто - бактериальные инфекции; частота неизвестна - кандидоз кожи.\u003Cbr\u003EСо стороны иммунной системы: нечасто - гиперчувствительность.\u003Cbr\u003EСо стороны эндокринной системы: частота неизвестна - гипертиреоз.\u003Cbr\u003EСо стороны нервной системы: часто - головная боль, головокружение, дисгевзия.\u003Cbr\u003EСо стороны органа слуха и вестибулярного аппарата: нечасто - вертиго.\u003Cbr\u003EСо стороны дыхательной системы: часто - инфекции верхних дыхательных путей; нечасто - носовое кровотечение.\u003Cbr\u003EСо стороны пищеварительной системы: часто - боль в животе, запор, диарея, тошнота, рвота; нечасто - вздутие живота, метеоризм, неприятный запах изо рта; частота неизвестна - псевдомембранозный колит*, желудочно-кишечные расстройства, диспепсия.\u003Cbr\u003EСо стороны кожи и подкожных тканей: часто - зуд кожи, сыпь; нечасто - крапивница, эритема; частота неизвестна - макуло-папулезная сыпь.\u003Cbr\u003EСо стороны костно-мышечной системы: часто - боль в спине.\u003Cbr\u003EСо стороны мочевыделительной системы: часто - инфекции мочевыводящих путей, глюкозурия, протеинурия; нечасто - дизурия.\u003Cbr\u003EБеременность, послеродовые и перинатальные состояния: часто - аномальные роды.\u003Cbr\u003EСо стороны половых органов и молочной железы: очень часто - вульвовагинальный кандидоз; часто - вульвовагинит, вульвовагинальные расстройства, нарушение менструального цикла, вульвовагинальная боль, метроррагия, выделения из влагалища; нечасто - трихомонадный вульвовагинит, вагинальные инфекции, боль в тазу; частота неизвестна - эндометриоз.\u003Cbr\u003EОбщие расстройства и реакции в месте в ведения: частота неизвестна - воспаление, боль.\u003Cbr\u003EДанные лабораторных и инструментальных исследований: нечасто - отклонение результатов микробиологических анализов от нормы.\u003Cbr\u003E* Нежелательные лекарственные реакции, выявленные в пострегистрационном периоде."},{"name":"Фармакологическое действие","value":"Бутоконазол - производное имидазола, обладает фунгицидной активностью в отношении грибов Candida, Trichophyton, Microsporum, Epidermaphyton и некоторых грамположительных бактерий. Наиболее эффективен при кандидозах.\u003Cbr\u003EБлокируя в клеточной мембране образование эргостерола из ланостерола, увеличивает проницаемость мембраны, что приводит к лизису клетки гриба. Клиндамицин - бактериостатический антибиотик из группы линкозамидов, обладает широким спектром действия, связывается с 50S субъединицей рибосомальной мембраны и подавляет синтез белка в микробной клетке. В отношении ряда грамположительных кокков возможно бактерицидное действие.\u003Cbr\u003EВ условиях in vitro к клиндамицину чувствительны следующие микроорганизмы, вызывающие бактериальные вагинозы: Gardnerella vaginalis, Mobiluncus spp., Mycoplasma hominis, Bacteroides spp., Peptostreptococcus spp.\u003Cbr\u003EГидрофильная кремовая основа обеспечивает препарату гелеобразную консистенцию при температуре 35-40 °С. При интравагинальном применении крем не плавится, в связи с чем активные вещества находятся на слизистой оболочке влагалища в течение 1-3 дней.\u003Cbr\u003EСуществует перекрестная резистентность между клиндамицином и линкомицином."},{"name":"Фармакологическая группа","value":"противомикробное и противогрибковое средство"},{"name":"Форма выпуска","value":"крем"},{"name":"Способ применения/введения","value":"интравагинально, местный"},{"name":"Пол","value":"для женщин"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре от 15 до 25 °C. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При интравагинальном применении препарата передозировка не установлена. Возможна абсорбция клиндамицина в количествах, достаточных для развития системных реакций.\u003Cbr\u003EСлучайное попадание препарата в желудочно-кишечный тракт также может вызвать системные эффекты, сходные с теми, который возникают после приема внутрь клиндамицина в терапевтических дозах. К возможным системным побочным эффектам можно отнести диарею, геморрагическую диарею, включая псевдомембранозный колит (см. разделы \"Побочное действие\" и \"Особые указания\"). Лечение: симптоматическое и поддерживающее."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата в период беременности и лактации возможно только в том случае, если потенциальная польза для матери превышает риск для плода или ребенка.\u003Cbr\u003EАдекватных контролируемых исследований по применению препарата в I триместре беременности не проводилось, поэтому Клиндацин Б пролонг можно назначать женщинам в I триместре беременности только по абсолютным показаниям, т.е. когда потенциальная польза терапии препаратом для матери превосходит потенциальный риск для плода. В исследованиях на животных при введении клиндамицина подкожно или внутрь каких-либо отрицательных влияний на плод не обнаружено, за исключением случаев приема препарата в дозах, токсичных для матери. При применении клиндамицина интравагинально во II или III триместре беременности увеличения частоты врожденных аномалий плода не отмечалось. Аномальные роды имели место у 1,1% женщин по сравнению с 0,5% в группе плацебо, если клиндамицин крем вагинальный применялся во II триместре в течение 7 дней. Применение препарата во П-Ш триместре беременности возможно, если потенциальная польза для матери превосходит риск для плода.\u003Cbr\u003EНеизвестно, выделяется ли клиндамицин в грудное молоко после интравагинального применения. Клиндамицин обнаружен в грудном молоке после перорального или парентерального введения, поэтому в период грудного вскармливания следует либо отменить применение препарата, либо прекратить грудное вскармливание, учитывая степень важности применения препарата для матери."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Нет оснований полагать, что применение препарата Клиндацин Б Пролонг крем вагинальный может оказывать влияние на способность к вождению автомобиля и управлению механизмами."},{"name":"Особые указания","value":"До назначения препарата с помощью соответствующих лабораторных методов должны быть исключены Trichomonas vaginalis, Chlamidia trachomatis, Neisseria gonorrhoeae и Herpes simplex virus, часто вызывающие вульвовагинит.\u003Cbr\u003E\n\u003Cbr\u003EИнтравагинальное применение клиндамицина может привести к усиленному росту нечувствительных микроорганизмов, особенно дрожжеподобных грибов.\u003Cbr\u003E\n\u003Cbr\u003EПрименение клиндамицина (как и практически всех антибиотиков) внутрь или парентерально связано с развитием тяжелой диареи и в ряде случаев псевдомембранозного колита. При развитии выраженной или длительной диареи препарат следует отменить и при необходимости провести соответствующее диагностические и лечебные мероприятия.\u003Cbr\u003E\u003Cbr\u003EПациентов следует предупредить о том, что во время терапии препаратом не следует вступать в половые сношения.\u003Cbr\u003E\u003Cbr\u003EВагинальный крем не рекомендуется использовать одновременно с другими интраваги- нальными лекарственными средствами.\u003Cbr\u003E\u003Cbr\u003EНе рекомендуется применение препарата в период менструации. Следует отложить начало терапии до окончания менструации.\u003Cbr\u003E\u003Cbr\u003EПрепарат содержит компоненты, которые могут уменьшить прочность изделий из латекса или каучука, поэтому использование презервативов, влагалищных противозачаточных диафрагм и других средств из латекса для интравагинального применения во время терапии препаратом и в течение 72 часов после применения не рекомендуется.\u003Cbr\u003E\u003Cbr\u003EЕсли клинические признаки инфекции сохраняются после завершения лечения, следует провести повторное микробиологическое исследование для выявления возбудителя и подтверждения диагноза.\u003Cbr\u003E\u003Cbr\u003EВходящий в состав препарата цетостеариловый спирт может вызвать местные кожные реакции (сыпь, контактный дерматит). Появление раздражения слизистой оболочки влагалища или болезненных ощущений, служит показанием к прекращению лечения."},{"name":"Взаимодействие","value":"Существует перекрестная резистентность между клиндамицином и линкомицином. В условиях in vitro продемонстрирован анатагонизм между клиндамицином и эритромицином. Установлено, что клиндамицин при системном применении нарушает нейромышечную передачу и, следовательно, может усиливать действие миорелаксантов периферического действия, поэтому препарат следует применять с осторожностью у больных, получающих препараты данной группы. Совместное применение с другими препаратами для интравагиналыюго введения не рекомендуется. Несовместим с растворами, содержащими комплекс витаминов группы В, аминогликозидами, ампициллином, кальция глюконатом и магния сульфатом."},{"name":"Регистрационный номер","value":"ЛП-001855"},{"name":"Дата государственной регистрации","value":"22.06.2022"},{"name":"Владелец регистрационного удостоверения","value":"АКРИХИН"},{"name":"Изготовитель","value":"АКРИХИН"},{"name":"Фасовщик","value":"АКРИХИН"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Клиндацин"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_4801470049198593134"}}}}
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    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  • Клиндацин супп. ваг., 100 мг, 3 шт.
    ВАМ–16 %
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    Клиндацин супп. ваг., 100 мг, 3 шт.

    Рейтинг товара: 4.9 из 5
    на основе 24 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 672 ₽ вместо 686
    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  • Клиндацин крем ваг. туба, 20 г, 1 шт.
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    Клиндацин крем ваг. туба, 20 г, 1 шт.

    Рейтинг товара: 4 из 5
    на основе 9 оценок
    Цена 687 ₽
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  • Клиндацин супп. ваг., 100 мг, 3 шт.
    –17 %
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    Клиндацин супп. ваг., 100 мг, 3 шт.

    Рейтинг товара: 5 из 5
    на основе 53 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 729 ₽ вместо 736
    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  • Вагилак гель для интимной гигиены, 50 мл, 50 г
    –2 %
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    Вагилак гель для интимной гигиены, 50 мл, 50 г

    Рейтинг товара: 5 из 5
    на основе 31 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 673 ₽ вместо 687
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  • Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.
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    Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.

    Рейтинг товара: 4.6 из 5
    на основе 1044 оценки
    Цена 216 ₽
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  • Клиндамицин крем ваг. туба, 20 г, 1 шт.
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    Клиндамицин крем ваг. туба, 20 г, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 517 ₽
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  • Силденафил Реневал таб., 50 мг, 10 шт.
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    Силденафил Реневал таб., 50 мг, 10 шт.

    Рейтинг товара: 4.7 из 5
    на основе 322 оценки
    Цена 290 ₽
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  • Эпиген интим гель д/нар. прим. фл., 250 мл, 300 г, 1 шт., 1 уп.
    –22 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ezfobksw109/toggleWishlist":{"skuId":"101796150745","productId":591009006,"offerId":"iNThzkBGZ6MkcqV0gtE0sw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzPafkqCazfguEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI7qnomQIQ2fuXnPsCGILGhhEg7tzBBw==","sign":"J6sNdIUz3UjY8bhA+H7DiKAAGxHeevj1ScWyD/ah57c="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ezfobksw109/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эпиген интим гель д/нар. прим. фл., 250 мл, 300 г, 1 шт., 1 уп.

    Рейтинг товара: 4.9 из 5
    на основе 1102 оценки
    Цена 1 620 ₽ вместо 2 090
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  • Гинофлор Э таб. ваг., 6 шт.
    –1 %
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    Гинофлор Э таб. ваг., 6 шт.

    Рейтинг товара: 5 из 5
    на основе 22 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 023 ₽ вместо 1 033
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  • Эстрогиал гель, 40 мл
    –1 %
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    Эстрогиал гель, 40 мл

    Рейтинг товара: 4.8 из 5
    на основе 45 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 645 ₽ вместо 652
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  • Тержинан таб. ваг., 6 шт.
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    Тержинан таб. ваг., 6 шт.

    Рейтинг товара: 4.5 из 5
    на основе 15 оценок
    Цена 699 ₽
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Инструкция

Показания к применению

Бактериальные вагинозы, грибковые и смешанные вагиниты, вызванные чувствительными к лекарственному средству микроорганизмами.

Противопоказания

Повышенная чувствительность к клиндамицину, линкомицину, бутоконазолу или любому компоненту препарата; воспалительные заболевания кишечника (болезнь Крона, язвенный, псевдомембранозный и антибиотик-ассоциированный колиты (в том числе в анамнезе)); детский возраст до 18 лет.

Способ применения и дозы

Вводится интравагинально с помощью аппликатора. Применяется 1 раз в день, предпочтительно перед сном. Рекомендуемая доза составляет один полный аппликатор (5 г крема, что соответствует 100 мг бутоконазола нитрата и 100 мг клиндамицина). Курс лечения - ежедневно в течение 3-х дней.
Инструкция по использованию аппликатора
Одноразовые аппликаторы, прилагающиеся к упаковке, предназначены для точного дозирования и введения крема Клиндаци Б пролонг во влагалище.
1. Откройте тубу с кремом, сняв колпачок. Проколите мембрану тубы обратной стороной колпачка. Навинтите пластмассовый аппликатор на снабженное резьбой горлышко тюбика.
2. Мягко надавливая на тубу с противоположного конца, осторожно выдавите крем в аппликатор. Поршень аппликатора двигается самостоятельно по мере заполнения необходимого объема. Аппликатор заполнен, когда поршень доходит до упора. Отвинтите аппликатор и закройте тубу колпачком
3. В положении лежа на спине подтяните колени к груди. Держа аппликатор горизонтально, осторожно введите его во влагалище как можно глубже, стараясь не вызвать неприятных ощущений.
4. Медленно надавливая на поршень до упора, введите весь объем крема во влагалище.
5. Осторожно извлеките аппликатор из влагалища и выбросите его в мусорный контейнер.
Полная инструкция
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Клиндацин Б пролонг крем ваг.
Клиндацин Б пролонг крем ваг., 20 г, 1 шт.
5.0
(2)
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2 вопроса
Инструкция

784 ₽

Скидка: 13%
–13 %
Вместо:902 ₽
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5.0
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