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Описание

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Дексилант капс. с модиф. высвоб., 60 мг, 28 шт.

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Коротко о товаре

Артикул Маркета
3492227444
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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НЭРБ - неэрозивная рефлюксная болезнь)."},{"name":"Противопоказания","value":"— повышенная чувствительность к любому из компонентов препарата;\u003Cbr\u003E— совместное применение с ингибиторами протеаз ВИЧ, абсорбция которых зависит от pH среды желудка (таких как атазанавир, нелфинавир) из-за значительного уменьшения их биодоступности;\u003Cbr\u003E— возраст до 18 лет;\u003Cbr\u003E— беременность;\u003Cbr\u003E— период лактации.\u003Cbr\u003EПрепарат содержит сахарозу, поэтому его применение не рекомендовано пациентам с наследственной непереносимостью фруктозы, глюкозо-галактозной мальабсорбцией или сахаразно-изомальтазной недостаточностью."},{"name":"Состав","value":"Состав на 1 капсулу 30 мг\u003Cbr\u003EАктивное вещество: декслансопразол 30 мг.\u003Cbr\u003EВспомогательные вещества: сахарная крупка1 (от 500 мкм до 710 мкм) 28,8 мг, магния карбонат 11,5 мг, сахароза 41,5 мг, гипролоза низкозамещенная 8,64 мг, гипролоза 0,34 мг, гипромеллоза 2910 7,54 мг, тальк 16,64 мг, титана диоксид 5,5 мг, дисперсия метакриловой кислоты сополимера2 9,66 мг, макрогол-8000 0,96 мг, полисорбат-80 0,44 мг, кремния диоксид коллоидный 0,09 мг, метакриловой кислоты и метилметакрилата сополимер [1:2] 15,95 мг, метакриловой кислоты и метилметакрилата сополимер[1:1] 5,32 мг, триэтилцитрат 2,12 мг;\u003Cbr\u003EОболочка капсулы: каррагинан 0,192-0,624 мг, калия хлорид 0,144-0,48 мг, титана диоксид 2,4768 мг, краситель FD & С синий №2 алюминиевый лак 0,3456 мг, краситель железа оксид черный 0,0576 мг, гипромеллоза q.s. до 48 мг, чернила серые очищенные для маркировки3 следовые количества.\u003Cbr\u003EСостав сахарной крупки: сахароза 18-26,352 мг, крахмал кукурузный 2,448-10,8 мг;\u003Cbr\u003E Состав дисперсии метакриловой кислоты сополимера: метакриловая кислота 4,4436 мг, этилакрилат 4,2504 мг, натрия лаурилсульфат 0,2254 мг, полисорбат-80 0,7406 мг;\u003Cbr\u003EСостав на 1 капсулу 60 мг\u003Cbr\u003EАктивное вещество: декслансопразол 60 мг.\u003Cbr\u003EВспомогательные вещества: сахарная крупка1 (от 500 мкм до 710 мкм) 40,0 мг, магния карбонат 16,0 мг, сахароза 39,52 мг, гипролоза низкозамещенная 12,0 мг, гипролоза 0,48 мг, гипромеллоза 2910 10,5067 мг, тальк 27,5499 мг, титана диоксид 6,9933 мг, дисперсия метакриловой кислоты сополимера2 7,02 мг, макрогол-8000 0,7 мг, полисорбат-80 0,32 мг, кремния диоксид коллоидный 0,13 мг, метакриловой кислоты и метилметакрилата сополимер [1:2] 31,9 мг, метакриловой кислоты и метилметакрилата сополимер [1:1] 10,64 мг, триэтилцитрат 4,24 мг.\u003Cbr\u003EОболочка капсулы: каррагинан 0,24-0,78 мг, калия хлорид 0,18-0,6 мг, титана диоксид 2,52 мг, краситель FD & С синий №2 алюминиевый лак 1,08 мг, гипромеллоза q.s. до 60 мг, чернила серые очищенные для маркировки3 следовые количества.\u003Cbr\u003EСостав сахарной крупки: сахароза 25-36,6 мг, крахмал кукурузный 3,4-15 мг;\u003Cbr\u003E Состав дисперсии метакриловой кислоты сополимера: метакриловая кислота 3,2292 мг, этилакрилат 3,0888 мг, натрия лаурилсульфат 0,1638 мг, полисорбат-80 0,5382 мг;\u003Cbr\u003EЧернила серые очищенные для маркировки состоят из красителя железа оксида красного, красителя железа оксида желтого, красителя FD & С синего №2 алюминиевого лака, воска карнаубского, шеллака, глицерила моноолеата."},{"name":"Действующее вещество","value":"Декслансопразол","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28708248"]}}},{"name":"Способ применения и дозы","value":"Внутрь: капсулу принимают целиком вне зависимости от приема пищи. Также можно капсулу открыть, высыпать из нее гранулы в столовую ложку и смешать их с яблочным пюре; затем немедленно, не разжевывая, проглотить.\u003Cbr\u003EЛечение эрозивного эзофагита любой степени тяжести: рекомендуемая доза составляет 60 мг 1 раз/сут. Курс лечения - 8 недель.\u003Cbr\u003EПоддерживающая терапия после лечения эрозивного эзофагита и облегчение проявлений изжоги: рекомендуемая доза составляет 30 мг 1 раз/сут. В проведенных исследованиях курс лечения составлял до 6 месяцев.\u003Cbr\u003EПри эрозивном эзофагите средней и тяжелой степени рекомендуемая доза составляет 60 мг 1 раз/сут. В проведенных исследованиях курс лечения составлял до 6 месяцев.\u003Cbr\u003EСимптоматическое лечение гастроэзофагеальной рефлюксной болезни ГЭРБ (т.е. НЭРБ - неэрозивная рефлюксная болезнь): рекомендуемая доза составляет 30 мг 1 раз/сут. Курс лечения - 4 недели.\u003Cbr\u003EУ пациентов с нарушениями функции печени средней степени тяжести (класс В по Чайлд-Пью) суточная доза не должна превышать 30 мг декслансопразола.\u003Cbr\u003EКлинические данные о приеме препарата у пациентов с нарушениями тяжелой степени (класс С по Чайлд-Пью) отсутствуют.\u003Cbr\u003EКоррекции дозы у пациентов пожилого возраста, пациентов с нарушением функции почек и с нарушением функции печени легкой степени тяжести (класс А по Чайлд-Пью) не требуется."},{"name":"Побочные действия","value":"Наиболее часто (не менее 2%): диарея, метеоризм, боли в животе, тошнота, рвота, инфекции верхних дыхательных путей.\u003Cbr\u003EОпределение частоты побочных реакций: очень часто (≥1/10), часто (≥1/100 и \u003C1/10), нечасто (≥1/1000 и \u003C1/100), редко (≥1/10 000 и \u003C1/1000), очень редко (\u003C1/10 000, включая отдельные случаи), частота неизвестна (невозможно оценить на основании имеющихся данных). \u003Cbr\u003EСо стороны иммунной системы: частота неизвестна - гиперчувствительность (в т.ч. анафилактические реакции), злокачественная экссудативная эритема (синдром Стивенса-Джонсона), токсический эпидермальный некролиз, эксфолиативный дерматит, анафилактический шок.\u003Cbr\u003EСо стороны обмена веществ: частота неизвестна - гипомагниемия, гипонатриемия.\u003Cbr\u003EСо стороны пищеварительной системы: часто - диарея, дискомфорт и боль в животе, запор, метеоризм, тошнота, рвота; нечасто - сухость во рту; редко - кандидоз полости рта; частота неизвестна - отек слизистой рта, панкреатит.\u003Cbr\u003EСо стороны мочевыводящей системы: частота неизвестна - острая почечная недостаточность.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: нечасто - изменение показателей функциональной активности печени; частота неизвестна - лекарственный гепатит.\u003Cbr\u003EСо стороны кожи и подкожных тканей: нечасто - сыпь, крапивница, зуд; частота неизвестна - лейкоцитокластический васкулит, генерализованная сыпь.\u003Cbr\u003EСо стороны дыхательной системы: часто - инфекционные заболевания верхних дыхательных путей; нечасто - кашель; частота неизвестна - отек гортани, чувство стеснения в горле.\u003Cbr\u003EСо стороны крови и лимфатической системы: частота неизвестна - аутоиммунная гемолитическая анемия, идиопатическая тромбоцитопеническая пурпура.\u003Cbr\u003EСо стороны костно-мышечной системы: частота неизвестна - переломы.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: нечасто - приступ жара (\"приливы\"), повышение АД.\u003Cbr\u003EСо стороны нервной системы: часто - головная боль; нечасто - головокружение, дисгевзия; редко - парестезия, судороги; частота неизвестна - инсульт, транзиторная ишемическая атака.\u003Cbr\u003EСо стороны органа зрения: редко - нарушение зрения; частота неизвестна - нарушение зрения (затуманивание).\u003Cbr\u003EСо стороны органа слуха и лабиринтные нарушения: редко - вертиго; частота неизвестна - снижение слуха.\u003Cbr\u003EНарушения психики: нечасто - бессонница, депрессия; редко - слуховые галлюцинации.\u003Cbr\u003EОбщие расстройства: нечасто - слабость, изменения аппетита; частота неизвестна - отек лица."},{"name":"Фармакологическое действие","value":"Ингибитор протонового насоса. Подавляет секрецию желудочного сока путем угнетения Н+/К+-АТФ-азы в париетальных клетках желудка. Блокирует заключительную стадию секреции соляной кислоты.\u003Cbr\u003EКапсула препарата Дексилант® распадается в желудке и содержит два типа гранул, покрытых кишечнорастворимой оболочкой, которые высвобождают активное вещество в зависимости от рН в различных областях тонкого кишечника. Данная комбинация помогает пролонгировать действие декслансопразола и способствует снижению секреции желудочного сока в течение продолжительного времени."},{"name":"Фармакологическая группа","value":"ингибиторы протонного насоса"},{"name":"Форма выпуска","value":"капсулы"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей, сухом месте при температуре не выше 25°С. Срок годности при фасовке во флаконы - 4 года, при фасовке в блистеры - 3 года. Не использовать после истечения срока годности, указанного на упаковке."},{"name":"Передозировка","value":"Сообщений о значимых случаях передозировки в результате применения препарата Дексилант не отмечено.\u003Cbr\u003EСимптомы: многократный прием дозы по 120 мг и однократный прием в дозе 300 мг не вызывали тяжелых побочных эффектов. При приеме препарата Дексилант® по 60 мг 2 раза/сут наблюдалось повышение АД более 140/90 мм рт.ст.\u003Cbr\u003EЛечение: в случае передозировки и только при наличии клинических проявлений проводится симптоматическая терапия. Декслансопразол не выводится посредством гемодиализа."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Дексилант в период беременности противопоказано. При необходимости применения препарата в период лактации следует прекратить грудное вскармливание."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Из-за вероятности головокружения и нарушения зрения пациентам в период лечения следует воздержаться от управления транспортными средствами и другими механизмами, требующими повышенного внимания."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003E— пациентам, принимающим такролимус;\u003Cbr\u003E— пациентам, принимающим ингибиторы изофермента CYP2C19, такие как флувоксамин;\u003Cbr\u003E— пациентам, принимающим варфарин (под контролем протромбинового времени и MHO);\u003Cbr\u003E— пациентам, принимающим метотрексат.\u003Cbr\u003EПеред началом лечения декслансопразолом следует исключить возможность злокачественного новообразования, поскольку препарат может маскировать симптомы и отсрочить правильную постановку диагноза.\u003Cbr\u003EЕсли симптомы сохраняются, несмотря на адекватное лечение, то следует провести дальнейшее обследование.\u003Cbr\u003EПри приеме ингибиторов протонного насоса, к которым относится декслансопразол, повышается риск желудочно-кишечных инфекций, сопровождающиеся диареей, возбудителями которых являются бактерии рода Clostridium difficile, особенно у госпитализированных пациентов. Это необходимо принять во внимание в случае, если при лечении диареи состояние пациента не улучшается.\u003Cbr\u003EПациентам в данном случае рекомендуется принимать минимально эффективную дозу декслансопразола при наименьшей продолжительности лечения.\u003Cbr\u003EУ пациентов, получающих высокие дозы препарата или при длительной терапии ингибиторами протонного насоса (ИПН) в течение года и более, возрастает риск остеопоротических переломов костей бедер, кистей и позвоночника. Пациенты с риском возникновения остеопоротических переломов должны придерживаться рекомендуемых дозировок (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EВ редких случаях у пациентов наблюдалась симптоматическая и асимптоматическая гипомагниемия при приеме препаратов ИПН в течение не менее трех месяцев, а в большинстве случаев - при приеме в течение года. Симптомами гипомагниемии являются тетания, аритмия и судороги. Лечение - восполнение магния и отмена приема препаратов ИПН. У пациентов, которым необходимо продолжительное лечение или одновременно принимающих препараты ИПН с дигоксином или другими препаратами, способными вызвать гипомагниемию (например, диуретики), необходимо контролировать концентрацию магния в сыворотке крови до начала и во время лечения."},{"name":"Взаимодействие","value":"Декслансопразол может быть назначен без риска лекарственного взаимодействия пациентам, принимающим клопидогрел. В случае совместного приема коррекции дозы клопидогрела не требуется. \u003Cbr\u003EТакже отмечено отсутствие клинически значимого лекарственного взаимодействия с фенитоином, теофиллином и диазепамом. \u003Cbr\u003EОдновременное применение декслансопразола может влиять на всасывание препаратов, биодоступность которых зависит от рН среды желудка (например, сложные эфиры ампицилина, дигоксин, соли железа, кетоконазол, эрлотиниб). \u003Cbr\u003EОдновременный прием с такролимусом может привести к увеличению концентрации такролимуса в плазме крови, особенно у пациентов после трансплантации, которые являются умеренными или медленными метаболизаторами по изоферменту CYP2C19. \u003Cbr\u003EПри одновременном приеме с флувоксамином существует вероятность увеличения системного воздействия декслансопразола. \u003Cbr\u003EОдновременный прием декслансопразола и метотрексата может привести к повышению и сохранению высокой концентрации метотрексата и/или его метаболита в сыворотке крови, что, соответственно может привести к развитию токсичности метотрексата. При необходимости приема высоких доз метотрексата рекомендуется временная отмена приема декслансопразола."},{"name":"Регистрационный номер","value":"ЛП-002477"},{"name":"Дата государственной регистрации","value":"27.05.2019"},{"name":"Владелец регистрационного удостоверения","value":"Такеда Фармасьютикалс","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:16227838"]}}},{"name":"Изготовитель","value":"Takeda"},{"name":"Страна бренда","value":"США"},{"name":"Страна-производитель","value":"Япония"},{"name":"Название препарата","value":"Дексилант","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["17796364:18014630"]}}},{"name":"Срок годности","value":"709 дн."}]}},"fullSpecsGrouped":{"16391777575601750829":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"желудок, пищеварительная система"},{"name":"Назначение","value":"гастроэзофагиальный рефлюкс, изжога, профилактика гастроэзофагеальной рефлюксной болезни, рефлюкс-эзофагит"},{"name":"Показания к применению","value":"— лечение эрозивного эзофагита любой степени тяжести;\u003Cbr\u003E— поддерживающая терапия после лечения эрозивного эзофагита и облегчение проявлений изжоги;\u003Cbr\u003E— симптоматическое лечение гастроэзофагеальной рефлюксной болезни ГЭРБ (т.е. НЭРБ - неэрозивная рефлюксная болезнь)."},{"name":"Противопоказания","value":"— повышенная чувствительность к любому из компонентов препарата;\u003Cbr\u003E— совместное применение с ингибиторами протеаз ВИЧ, абсорбция которых зависит от pH среды желудка (таких как атазанавир, нелфинавир) из-за значительного уменьшения их биодоступности;\u003Cbr\u003E— возраст до 18 лет;\u003Cbr\u003E— беременность;\u003Cbr\u003E— период лактации.\u003Cbr\u003EПрепарат содержит сахарозу, поэтому его применение не рекомендовано пациентам с наследственной непереносимостью фруктозы, глюкозо-галактозной мальабсорбцией или сахаразно-изомальтазной недостаточностью."},{"name":"Состав","value":"Состав на 1 капсулу 30 мг\u003Cbr\u003EАктивное вещество: декслансопразол 30 мг.\u003Cbr\u003EВспомогательные вещества: сахарная крупка1 (от 500 мкм до 710 мкм) 28,8 мг, магния карбонат 11,5 мг, сахароза 41,5 мг, гипролоза низкозамещенная 8,64 мг, гипролоза 0,34 мг, гипромеллоза 2910 7,54 мг, тальк 16,64 мг, титана диоксид 5,5 мг, дисперсия метакриловой кислоты сополимера2 9,66 мг, макрогол-8000 0,96 мг, полисорбат-80 0,44 мг, кремния диоксид коллоидный 0,09 мг, метакриловой кислоты и метилметакрилата сополимер [1:2] 15,95 мг, метакриловой кислоты и метилметакрилата сополимер[1:1] 5,32 мг, триэтилцитрат 2,12 мг;\u003Cbr\u003EОболочка капсулы: каррагинан 0,192-0,624 мг, калия хлорид 0,144-0,48 мг, титана диоксид 2,4768 мг, краситель FD & С синий №2 алюминиевый лак 0,3456 мг, краситель железа оксид черный 0,0576 мг, гипромеллоза q.s. до 48 мг, чернила серые очищенные для маркировки3 следовые количества.\u003Cbr\u003EСостав сахарной крупки: сахароза 18-26,352 мг, крахмал кукурузный 2,448-10,8 мг;\u003Cbr\u003E Состав дисперсии метакриловой кислоты сополимера: метакриловая кислота 4,4436 мг, этилакрилат 4,2504 мг, натрия лаурилсульфат 0,2254 мг, полисорбат-80 0,7406 мг;\u003Cbr\u003EСостав на 1 капсулу 60 мг\u003Cbr\u003EАктивное вещество: декслансопразол 60 мг.\u003Cbr\u003EВспомогательные вещества: сахарная крупка1 (от 500 мкм до 710 мкм) 40,0 мг, магния карбонат 16,0 мг, сахароза 39,52 мг, гипролоза низкозамещенная 12,0 мг, гипролоза 0,48 мг, гипромеллоза 2910 10,5067 мг, тальк 27,5499 мг, титана диоксид 6,9933 мг, дисперсия метакриловой кислоты сополимера2 7,02 мг, макрогол-8000 0,7 мг, полисорбат-80 0,32 мг, кремния диоксид коллоидный 0,13 мг, метакриловой кислоты и метилметакрилата сополимер [1:2] 31,9 мг, метакриловой кислоты и метилметакрилата сополимер [1:1] 10,64 мг, триэтилцитрат 4,24 мг.\u003Cbr\u003EОболочка капсулы: каррагинан 0,24-0,78 мг, калия хлорид 0,18-0,6 мг, титана диоксид 2,52 мг, краситель FD & С синий №2 алюминиевый лак 1,08 мг, гипромеллоза q.s. до 60 мг, чернила серые очищенные для маркировки3 следовые количества.\u003Cbr\u003EСостав сахарной крупки: сахароза 25-36,6 мг, крахмал кукурузный 3,4-15 мг;\u003Cbr\u003E Состав дисперсии метакриловой кислоты сополимера: метакриловая кислота 3,2292 мг, этилакрилат 3,0888 мг, натрия лаурилсульфат 0,1638 мг, полисорбат-80 0,5382 мг;\u003Cbr\u003EЧернила серые очищенные для маркировки состоят из красителя железа оксида красного, красителя железа оксида желтого, красителя FD & С синего №2 алюминиевого лака, воска карнаубского, шеллака, глицерила моноолеата."},{"name":"Действующее вещество","value":"Декслансопразол"},{"name":"Способ применения и дозы","value":"Внутрь: капсулу принимают целиком вне зависимости от приема пищи. Также можно капсулу открыть, высыпать из нее гранулы в столовую ложку и смешать их с яблочным пюре; затем немедленно, не разжевывая, проглотить.\u003Cbr\u003EЛечение эрозивного эзофагита любой степени тяжести: рекомендуемая доза составляет 60 мг 1 раз/сут. Курс лечения - 8 недель.\u003Cbr\u003EПоддерживающая терапия после лечения эрозивного эзофагита и облегчение проявлений изжоги: рекомендуемая доза составляет 30 мг 1 раз/сут. В проведенных исследованиях курс лечения составлял до 6 месяцев.\u003Cbr\u003EПри эрозивном эзофагите средней и тяжелой степени рекомендуемая доза составляет 60 мг 1 раз/сут. В проведенных исследованиях курс лечения составлял до 6 месяцев.\u003Cbr\u003EСимптоматическое лечение гастроэзофагеальной рефлюксной болезни ГЭРБ (т.е. НЭРБ - неэрозивная рефлюксная болезнь): рекомендуемая доза составляет 30 мг 1 раз/сут. Курс лечения - 4 недели.\u003Cbr\u003EУ пациентов с нарушениями функции печени средней степени тяжести (класс В по Чайлд-Пью) суточная доза не должна превышать 30 мг декслансопразола.\u003Cbr\u003EКлинические данные о приеме препарата у пациентов с нарушениями тяжелой степени (класс С по Чайлд-Пью) отсутствуют.\u003Cbr\u003EКоррекции дозы у пациентов пожилого возраста, пациентов с нарушением функции почек и с нарушением функции печени легкой степени тяжести (класс А по Чайлд-Пью) не требуется."},{"name":"Побочные действия","value":"Наиболее часто (не менее 2%): диарея, метеоризм, боли в животе, тошнота, рвота, инфекции верхних дыхательных путей.\u003Cbr\u003EОпределение частоты побочных реакций: очень часто (≥1/10), часто (≥1/100 и \u003C1/10), нечасто (≥1/1000 и \u003C1/100), редко (≥1/10 000 и \u003C1/1000), очень редко (\u003C1/10 000, включая отдельные случаи), частота неизвестна (невозможно оценить на основании имеющихся данных). \u003Cbr\u003EСо стороны иммунной системы: частота неизвестна - гиперчувствительность (в т.ч. анафилактические реакции), злокачественная экссудативная эритема (синдром Стивенса-Джонсона), токсический эпидермальный некролиз, эксфолиативный дерматит, анафилактический шок.\u003Cbr\u003EСо стороны обмена веществ: частота неизвестна - гипомагниемия, гипонатриемия.\u003Cbr\u003EСо стороны пищеварительной системы: часто - диарея, дискомфорт и боль в животе, запор, метеоризм, тошнота, рвота; нечасто - сухость во рту; редко - кандидоз полости рта; частота неизвестна - отек слизистой рта, панкреатит.\u003Cbr\u003EСо стороны мочевыводящей системы: частота неизвестна - острая почечная недостаточность.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: нечасто - изменение показателей функциональной активности печени; частота неизвестна - лекарственный гепатит.\u003Cbr\u003EСо стороны кожи и подкожных тканей: нечасто - сыпь, крапивница, зуд; частота неизвестна - лейкоцитокластический васкулит, генерализованная сыпь.\u003Cbr\u003EСо стороны дыхательной системы: часто - инфекционные заболевания верхних дыхательных путей; нечасто - кашель; частота неизвестна - отек гортани, чувство стеснения в горле.\u003Cbr\u003EСо стороны крови и лимфатической системы: частота неизвестна - аутоиммунная гемолитическая анемия, идиопатическая тромбоцитопеническая пурпура.\u003Cbr\u003EСо стороны костно-мышечной системы: частота неизвестна - переломы.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: нечасто - приступ жара (\"приливы\"), повышение АД.\u003Cbr\u003EСо стороны нервной системы: часто - головная боль; нечасто - головокружение, дисгевзия; редко - парестезия, судороги; частота неизвестна - инсульт, транзиторная ишемическая атака.\u003Cbr\u003EСо стороны органа зрения: редко - нарушение зрения; частота неизвестна - нарушение зрения (затуманивание).\u003Cbr\u003EСо стороны органа слуха и лабиринтные нарушения: редко - вертиго; частота неизвестна - снижение слуха.\u003Cbr\u003EНарушения психики: нечасто - бессонница, депрессия; редко - слуховые галлюцинации.\u003Cbr\u003EОбщие расстройства: нечасто - слабость, изменения аппетита; частота неизвестна - отек лица."},{"name":"Фармакологическое действие","value":"Ингибитор протонового насоса. Подавляет секрецию желудочного сока путем угнетения Н+/К+-АТФ-азы в париетальных клетках желудка. Блокирует заключительную стадию секреции соляной кислоты.\u003Cbr\u003EКапсула препарата Дексилант® распадается в желудке и содержит два типа гранул, покрытых кишечнорастворимой оболочкой, которые высвобождают активное вещество в зависимости от рН в различных областях тонкого кишечника. Данная комбинация помогает пролонгировать действие декслансопразола и способствует снижению секреции желудочного сока в течение продолжительного времени."},{"name":"Фармакологическая группа","value":"ингибиторы протонного насоса"},{"name":"Форма выпуска","value":"капсулы"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей, сухом месте при температуре не выше 25°С. Срок годности при фасовке во флаконы - 4 года, при фасовке в блистеры - 3 года. Не использовать после истечения срока годности, указанного на упаковке."},{"name":"Передозировка","value":"Сообщений о значимых случаях передозировки в результате применения препарата Дексилант не отмечено.\u003Cbr\u003EСимптомы: многократный прием дозы по 120 мг и однократный прием в дозе 300 мг не вызывали тяжелых побочных эффектов. При приеме препарата Дексилант® по 60 мг 2 раза/сут наблюдалось повышение АД более 140/90 мм рт.ст.\u003Cbr\u003EЛечение: в случае передозировки и только при наличии клинических проявлений проводится симптоматическая терапия. Декслансопразол не выводится посредством гемодиализа."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Дексилант в период беременности противопоказано. При необходимости применения препарата в период лактации следует прекратить грудное вскармливание."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Из-за вероятности головокружения и нарушения зрения пациентам в период лечения следует воздержаться от управления транспортными средствами и другими механизмами, требующими повышенного внимания."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003E— пациентам, принимающим такролимус;\u003Cbr\u003E— пациентам, принимающим ингибиторы изофермента CYP2C19, такие как флувоксамин;\u003Cbr\u003E— пациентам, принимающим варфарин (под контролем протромбинового времени и MHO);\u003Cbr\u003E— пациентам, принимающим метотрексат.\u003Cbr\u003EПеред началом лечения декслансопразолом следует исключить возможность злокачественного новообразования, поскольку препарат может маскировать симптомы и отсрочить правильную постановку диагноза.\u003Cbr\u003EЕсли симптомы сохраняются, несмотря на адекватное лечение, то следует провести дальнейшее обследование.\u003Cbr\u003EПри приеме ингибиторов протонного насоса, к которым относится декслансопразол, повышается риск желудочно-кишечных инфекций, сопровождающиеся диареей, возбудителями которых являются бактерии рода Clostridium difficile, особенно у госпитализированных пациентов. Это необходимо принять во внимание в случае, если при лечении диареи состояние пациента не улучшается.\u003Cbr\u003EПациентам в данном случае рекомендуется принимать минимально эффективную дозу декслансопразола при наименьшей продолжительности лечения.\u003Cbr\u003EУ пациентов, получающих высокие дозы препарата или при длительной терапии ингибиторами протонного насоса (ИПН) в течение года и более, возрастает риск остеопоротических переломов костей бедер, кистей и позвоночника. Пациенты с риском возникновения остеопоротических переломов должны придерживаться рекомендуемых дозировок (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EВ редких случаях у пациентов наблюдалась симптоматическая и асимптоматическая гипомагниемия при приеме препаратов ИПН в течение не менее трех месяцев, а в большинстве случаев - при приеме в течение года. Симптомами гипомагниемии являются тетания, аритмия и судороги. Лечение - восполнение магния и отмена приема препаратов ИПН. У пациентов, которым необходимо продолжительное лечение или одновременно принимающих препараты ИПН с дигоксином или другими препаратами, способными вызвать гипомагниемию (например, диуретики), необходимо контролировать концентрацию магния в сыворотке крови до начала и во время лечения."},{"name":"Взаимодействие","value":"Декслансопразол может быть назначен без риска лекарственного взаимодействия пациентам, принимающим клопидогрел. В случае совместного приема коррекции дозы клопидогрела не требуется. \u003Cbr\u003EТакже отмечено отсутствие клинически значимого лекарственного взаимодействия с фенитоином, теофиллином и диазепамом. \u003Cbr\u003EОдновременное применение декслансопразола может влиять на всасывание препаратов, биодоступность которых зависит от рН среды желудка (например, сложные эфиры ампицилина, дигоксин, соли железа, кетоконазол, эрлотиниб). \u003Cbr\u003EОдновременный прием с такролимусом может привести к увеличению концентрации такролимуса в плазме крови, особенно у пациентов после трансплантации, которые являются умеренными или медленными метаболизаторами по изоферменту CYP2C19. \u003Cbr\u003EПри одновременном приеме с флувоксамином существует вероятность увеличения системного воздействия декслансопразола. \u003Cbr\u003EОдновременный прием декслансопразола и метотрексата может привести к повышению и сохранению высокой концентрации метотрексата и/или его метаболита в сыворотке крови, что, соответственно может привести к развитию токсичности метотрексата. При необходимости приема высоких доз метотрексата рекомендуется временная отмена приема декслансопразола."},{"name":"Регистрационный номер","value":"ЛП-002477"},{"name":"Дата государственной регистрации","value":"27.05.2019"},{"name":"Владелец регистрационного удостоверения","value":"Такеда Фармасьютикалс"},{"name":"Изготовитель","value":"Takeda"},{"name":"Страна бренда","value":"США"},{"name":"Страна-производитель","value":"Япония"},{"name":"Название препарата","value":"Дексилант"},{"name":"Срок годности","value":"709 дн."}]}],"transitionId":"tr_4491135268760924014"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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2 955 ₽

Скидка: 11%
–11 %
Вместо:3 321 ₽
  • 8-10 июня, самовывоз • 0 ₽
POLZAru
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38Котзывов
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  • Альфазокс р-р д/вн прим. саше, 10 мл, 20 шт., 1 уп.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o0oyzioimm/toggleWishlist":{"skuId":"101422383738","productId":649931041,"offerId":"kUhs-GtA30OSl8gr3iJvNQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ98Ly14622oFvEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIodL0tQIQ+oT76fkCGOn09gcg2tnBBw==","sign":"xbF0VGBEhvcWrBW6aSS5T/tMb9nC3fp9L9w/vWnCKXA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o0oyzioimm/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Альфазокс р-р д/вн прим. саше, 10 мл, 20 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 153 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 155 ₽ вместо 1 167
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-o0oyzioimm/addToCartButton":{"offerId":"kUhs-GtA30OSl8gr3iJvNQ","skuId":"101422383738","pendingCartItem":{"productId":649931041,"offerId":"kUhs-GtA30OSl8gr3iJvNQ","showPlaceId":"OTNDnItfwRMjN9MRHuEMMv508q6AHPapIBNvr4-oCm4aUo5Zq2ITXDDu8yElgJrPOk3miC49NFmGbArVG0Z-gaBf2toeBB1Cm-z7Gkns3i2UHMEuZMVA5akSC2bHc99rJ09FIlkaYFkm2VgycgY9-hBkxvGJxduMq3ZQI2YAWbO4KFMwKsa-sjU2V4Nhti4Vs84u1zEE4Dwat5dHboHE2A,,","feeShow":"OTNDnItfwRMjN9MRHuEMMv508q6AHPapIBNvr4-oCm4aUo5Zq2ITXDDu8yElgJrPOk3miC49NFmGbArVG0Z-gaBf2toeBB1Cm-z7Gkns3i2UHMEuZMVA5akSC2bHc99rJ09FIlkaYFkm2VgycgY9-hBkxvGJxduMq3ZQI2YAWbO4KFMwKsa-sjU2V4Nhti4Vs84u1zEE4Dwat5dHboHE2A,,","skuId":"101422383738","shopId":11693184,"price":{"applicablePriceDiscounts":[{"priceWithDiscount":"1155","type":"ya-card","totalPercentWithDiscount":1}],"value":"1167","currency":"RUR"},"hid":"15756506","name":"Альфазокс р-р д/вн прим. саше, 10 мл, 20 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  • Фестал таб. п/о кш/раств., 20 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8h1rd7fc2yo/toggleWishlist":{"skuId":"228073283","productId":1400799455,"offerId":"phdeb_WXaWCvUq5-rL2gaw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ98Ly14622oFvEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI34H6mwUQw77gbBioxN4HINrZwQc=","sign":"67P8mOPvpn73RXQ2Q2gWnPyrP9Bt4pWEN64agWrrKdc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8h1rd7fc2yo/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Фестал таб. п/о кш/раств., 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 64 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 224 ₽ вместо 226
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8h1rd7fc2yo/addToCartButton":{"offerId":"phdeb_WXaWCvUq5-rL2gaw","skuId":"228073283","pendingCartItem":{"productId":1400799455,"offerId":"phdeb_WXaWCvUq5-rL2gaw","showPlaceId":"OTNDnItfwRMjN9MRHuEMMv508q6AHPapDaun_GjJTCUWS6w-cZope4T_MlT5yWeRAO-IUQcI-qi4NrnEZZMLnpHtSGEdFW7nYkoGBNOWMOOL_Yt_ZyiaU2B_pPGgRezW0FDILqPn_mCJTleaSo4SGpqibkgVxLzNH2QQi3OKBsdxDgKsuxchmg8RteIxxwCWwRtfqF58Tf_3CNYL6_6lJvtkP3nYUpdpC4szveHIu6E,","feeShow":"OTNDnItfwRMjN9MRHuEMMv508q6AHPapDaun_GjJTCUWS6w-cZope4T_MlT5yWeRAO-IUQcI-qi4NrnEZZMLnpHtSGEdFW7nYkoGBNOWMOOL_Yt_ZyiaU2B_pPGgRezW0FDILqPn_mCJTleaSo4SGpqibkgVxLzNH2QQi3OKBsdxDgKsuxchmg8RteIxxwCWwRtfqF58Tf_3CNYL6_6lJvtkP3nYUpdpC4szveHIu6E,","skuId":"228073283","shopId":431782,"price":{"applicablePriceDiscounts":[{"priceWithDiscount":"224","type":"ya-card","totalPercentWithDiscount":1}],"value":"226","currency":"RUR"},"hid":"15756506","name":"Фестал таб. 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  • Урсофальк капс., 250 мг, 100 шт.
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    Урсофальк капс., 250 мг, 100 шт.

    Рейтинг товара: 4.8 из 5
    на основе 118 оценок
    Цена 1 659 ₽
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  • Колофорт таб. д/рассас., 100 шт.
    –2 %
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    Колофорт таб. д/рассас., 100 шт.

    Рейтинг товара: 4.9 из 5
    на основе 18 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 735 ₽ вместо 751
    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таб. д/рассас., 100 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  • Дицетел таб. п/о, 50 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-a9jl4e7voqt/toggleWishlist":{"skuId":"101759825748","productId":227814211,"offerId":"GsWuTF-IjRpqksbdmP1_iA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ98Ly14622oFvEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIw9bQbBDU7u6K+wIY0MTeByDa2cEH","sign":"dVUfuQhvgTjuYJVOfT0FNHu7lFkpBhBn9jYjVNQlhWE="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-a9jl4e7voqt/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Дицетел таб. п/о, 50 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 640 ₽
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  • Ребагит таб. п/о плен., 100 мг, 30 шт.
    –21 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-26jkk6sm6c4/toggleWishlist":{"skuId":"228063575","productId":1400799597,"offerId":"I-nVUhr3EcU_2BdlSUfHfQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ98Ly14622oFvEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI7YL6mwUQ1/LfbBik3dAHINrZwQc=","sign":"tuE74sO2r7/QRsGPUYE1DmYQO7wPAc6ciQ2qda9rTFQ="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-26jkk6sm6c4/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ребагит таб. п/о плен., 100 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 23 оценки
    Цена 857 ₽ вместо 1 085
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  • Ребагит таб. п/о плен., 100 мг, 30 шт.
    –17 %
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    Ребагит таб. п/о плен., 100 мг, 30 шт.

    Рейтинг товара: 4.6 из 5
    на основе 24 оценки
    Цена 1 000 ₽ вместо 1 210
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  • Контролок лиоф. д/приг. р-ра для в/в введ. фл., 40 мг
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    Контролок лиоф. д/приг. р-ра для в/в введ. фл., 40 мг

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 473 ₽
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  • Лактофильтрум таб., 120 мг + 355 мг, 60 шт.
    –2 %
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    Лактофильтрум таб., 120 мг + 355 мг, 60 шт.

    Рейтинг товара: 4.9 из 5
    на основе 196 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 604 ₽ вместо 616
    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таб., 120 мг + 355 мг, 60 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  • Рекицен-РД с фруктоолигосахаридами таб., 90 шт.
    –1 %
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    Рекицен-РД с фруктоолигосахаридами таб., 90 шт.

    Рейтинг товара: 4.7 из 5
    на основе 14 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 442 ₽ вместо 446
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  • Релиф Про супп. рект., 40 мг+ 1 мг, 10 шт.
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    Релиф Про супп. рект., 40 мг+ 1 мг, 10 шт.

    Рейтинг товара: 4.5 из 5
    на основе 44 оценки
    Цена 1 020 ₽
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Инструкция

Показания к применению

— лечение эрозивного эзофагита любой степени тяжести;
— поддерживающая терапия после лечения эрозивного эзофагита и облегчение проявлений изжоги;
— симптоматическое лечение гастроэзофагеальной рефлюксной болезни ГЭРБ (т.е. НЭРБ - неэрозивная рефлюксная болезнь).

Противопоказания

— повышенная чувствительность к любому из компонентов препарата;
— совместное применение с ингибиторами протеаз ВИЧ, абсорбция которых зависит от pH среды желудка (таких как атазанавир, нелфинавир) из-за значительного уменьшения их биодоступности;
— возраст до 18 лет;
— беременность;
— период лактации.
Препарат содержит сахарозу, поэтому его применение не рекомендовано пациентам с наследственной непереносимостью фруктозы, глюкозо-галактозной мальабсорбцией или сахаразно-изомальтазной недостаточностью.

Способ применения и дозы

Внутрь: капсулу принимают целиком вне зависимости от приема пищи. Также можно капсулу открыть, высыпать из нее гранулы в столовую ложку и смешать их с яблочным пюре; затем немедленно, не разжевывая, проглотить.
Лечение эрозивного эзофагита любой степени тяжести: рекомендуемая доза составляет 60 мг 1 раз/сут. Курс лечения - 8 недель.
Поддерживающая терапия после лечения эрозивного эзофагита и облегчение проявлений изжоги: рекомендуемая доза составляет 30 мг 1 раз/сут. В проведенных исследованиях курс лечения составлял до 6 месяцев.
При эрозивном эзофагите средней и тяжелой степени рекомендуемая доза составляет 60 мг 1 раз/сут. В проведенных исследованиях курс лечения составлял до 6 месяцев.
Симптоматическое лечение гастроэзофагеальной рефлюксной болезни ГЭРБ (т.е. НЭРБ - неэрозивная рефлюксная болезнь): рекомендуемая доза составляет 30 мг 1 раз/сут. Курс лечения - 4 недели.
У пациентов с нарушениями функции печени средней степени тяжести (класс В по Чайлд-Пью) суточная доза не должна превышать 30 мг декслансопразола.
Клинические данные о приеме препарата у пациентов с нарушениями тяжелой степени (класс С по Чайлд-Пью) отсутствуют.
Коррекции дозы у пациентов пожилого возраста, пациентов с нарушением функции почек и с нарушением функции печени легкой степени тяжести (класс А по Чайлд-Пью) не требуется.
Полная инструкция
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Дексилант капс. с модиф. высвоб.
Дексилант капс. с модиф. высвоб., 60 мг, 28 шт.
4.7
(3)
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5 вопросов
Инструкция

2 955 ₽

Скидка: 11%
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Вместо:3 321 ₽
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4.7
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