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Описание

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Октреотид р-р для в/в и п/к введ. амп., 50 мкг/мл, 1 мл, 5 шт.

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5.0
(1)
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Коротко о товаре

Артикул Маркета
4453140713
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Возможно назначение до 1200 мкг/сут, подбор дозы основан на определении концентрации амилазы, липазы, воспалительных цитокинов крови.\u003Cbr\u003EДля профилактики осложнений после операций на поджелудочной железе первую дозу Октреотида 100 мкг вводят п/к за 1 час до лапаротомии; затем после операции вводят п/к по 100 мкг 3 раза/сут на протяжении 7 последующих дней.\u003Cbr\u003EДля остановки кровотечения из варикозно расширенных вен пищевода препарат вводят в/в в дозе 25 мкг/ч в виде продолжительных инфузий в течение 5 дней.\u003Cbr\u003EДля остановки кровотечений при язвенной болезни желудка и 12-перстной кишки рекомендуется вводить Октреотид в виде в/в инфузий в дозе 25 мкг/ час в течение 5 дней.\u003Cbr\u003EУ больных пожилого возраста нет необходимости в снижении дозы Октреотида.\u003Cbr\u003EУ пациентов с нарушением функции почек коррекция режима дозирования октреотида не требуется.\u003Cbr\u003EУ пациентов с нарушением функции печени рекомендуется коррекция поддерживающей дозы, т.к. имеются данные об увеличении Т1/2 октреотида у больных циррозом печени.\u003Cbr\u003EОпыт применения октреотида у детей очень ограничен.\u003Cbr\u003EПравила приготовления и введения раствора\u003Cbr\u003EДля уменьшения явлений дискомфорта в месте введения, раствор Октреотида перед введением должен иметь комнатную температуру.\u003Cbr\u003EПри п/к введении препарата следует избегать нескольких инъекций в одно и то же место через короткие интервалы времени. Ампулы с препаратом следует открывать непосредственно перед введением, неиспользованное количество раствора следует уничтожить.\u003Cbr\u003EПри в/в введении следует внимательно осмотреть раствор на предмет прозрачности, наличия частиц, осадка, изменения цвета. Нельзя применять препарат, если он является мутным, содержит частицы, осадок. Октреотид в течение 24 часов сохраняет физическую и химическую стабильность в стерильном 0,9 % растворе натрия хлорида при температуре от 8 до 25 °С. Во избежание микробного загрязнения разведенные растворы следует использовать сразу после приготовления. Если раствор не будет использован сразу, его следует хранить при температуре от 2 до 8 °С вплоть до его применения. Перед использованием раствор следует подержать при комнатной температуре.\u003Cbr\u003EОбщее время между разведением, хранением в холодильнике и окончанием введения раствора не должно превышать 24 ч.\u003Cbr\u003EПри необходимости в/в введения содержимое одной ампулы, содержащей 300 мкг октреотида, должно быть разведено в 60 мл 0,9% раствора натрия хлорида, приготовленный раствор следует вводить в/в капельно. Инфузии повторяют с необходимой частотой в соответствии с рекомендованной длительностью лечения. Октреотид также можно вводить и в более низких концентрациях."},{"name":"Побочные действия","value":"Местные реакции: в месте инъекции возможны боль, ощущение зуда или жжение, краснота и припухлость (обычно проходят в течение 15 минут).\u003Cbr\u003EСо стороны ЖКТ, поджелудочной железы, печени и желчного пузыря: возможны - анорексия, тошнота, рвота, спастические боли в животе, ощущение вздутия живота, избыточное газообразование, жидкий стул, диарея и стеаторея. Хотя выделение жира с калом может возрастать, нет указаний на то, что длительное лечение октреотидом может приводить к нарушению всасывания (мальабсорбции). В редких случаях могут отмечаться явления, напоминающие острую кишечную непроходимость: прогрессирующее вздутие живота, выраженная боль в эпигастральной области, напряжение брюшной стенки.\u003Cbr\u003EДлительное использование октреотида может приводить к образованию камней в желчном пузыре.\u003Cbr\u003EИзвестны отдельные случаи острого гепатита без холестаза (нормализация показателей трансаминаз после отмены октреотида), а также гипербилирубинемии в сочетании с увеличением активности щелочной фосфатазы, гамма-глутамилтрансферазы и др. трансаминаз.\u003Cbr\u003EИмеются отдельные сообщения о редких случаях острого панкреатита, который развивался в первые часы или дни применения октреотида.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: в отдельных случаях - тахикардия, брадикардия.\u003Cbr\u003EСо стороны обмена веществ: возможно нарушение толерантности к глюкозе после приема пищи (октреотид оказывает подавляющее Действие на образование ГР, глюкагона и инсулина), гипогликемия; в редких случаях при длительном лечении возможно развитие персистирующей гипергликемии.\u003Cbr\u003EПрочие: редко - аллергические реакции, алопеция; в отдельных случаях - анафилактические реакции."},{"name":"Фармакологическое действие","value":"Октреотид - синтетический октапептид, производное естественного гормона соматостатина, обладает сходными с ним фармакологическими эффектами, но со значительно большей продолжительностью действия. Октреотид подавляет как патологически повышенную секрецию гормона роста (ГР), так и вызываемую аргинином, физической нагрузкой и инсулиновой гипогликемией. Препарат подавляет секрецию серотонина, гастрина, инсулина и глюкагона и других пептидов, продуцируемых в гастроэнтеропанкреатической эндокринной системе. У больных, которым проводятся операции на поджелудочной железе, применение октреотида во время операции и после нее снижает частоту типичных послеоперационных осложнений (острого послеоперационного панкреатита, панкреатических свищей, абсцессов, сепсиса).\u003Cbr\u003EПри кровотечениях из варикозно расширенных вен пищевода и желудка у больных циррозом печени применение октреотида в составе комплексной терапии приводит к эффективной остановке кровотечения, профилактике раннего повторного кровотечения и улучшению выживаемости. Механизм действия октреотида связан с уменьшением органного кровотока посредством подавления вазоактивных гормонов (вазоактивного интестинального пептида, глюкагона)."},{"name":"Фармакологическая группа","value":"соматостатина аналог синтетический"},{"name":"Форма выпуска","value":"раствор для инъекций и инфузий"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"sistemnye-gormonalnye-preparaty","categoryId":"15756915","navnodeId":"72510","glfilters":["35947170:36763748"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В защищенном от света месте при температуре не выше 25 °С. Не замораживать.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Известно, что введение октреотида в дозе до 2000 мкг в виде п/к инъекции 3 раза в течение нескольких месяцев переносилось хорошо.\u003Cbr\u003EМаксимальная разовая доза при в/в болюсном введении взрослому пациенту составляла 1000 мкг. При этом отмечались такие симптомы, как снижение частоты сердечных сокращений, \"приливы\" крови к лицу, абдоминальная боль спастического характера, диарея, тошнота, ощущение пустоты в желудке. Все эти симптомы разрешились в течение 24 часов с момента введения препарата.\u003Cbr\u003EОдному пациенту по ошибке методом длительной инфузии была введена избыточная доза октреотида 250 мкг/ч (вместо 25 мкг/ч), что не сопровождалось побочными эффектами.\u003Cbr\u003EПри острой передозировке не было отмечено каких-либо опасных для жизни реакций.\u003Cbr\u003EЛечение: симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Адекватных и контролируемых исследований не проводилось. Применение во время беременности и в период лактации только по абсолютным показаниям, с учетом соотношения риск/польза, т.е. когда предполагаемая польза для матери превышает предполагаемый риск для плода или грудного ребенка."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"На сегодняшний день не имеется данных о влиянии октреотида на способность водить автомобиль и работать с механизмами."},{"name":"Особые указания","value":"У больных сахарным диабетом 1 типа (получающих инсулин), октреотид может снижать потребность в инсулине. У пациентов без нарушения углеводного обмена и больных сахарным диабетом 2 типа введение препарата может приводить к постпрандиальной гликемии. Пациентам с сахарным диабетом на фоне гипогликемической терапии рекомендуется проводить контроль концентрации глюкозы в крови.\u003Cbr\u003EУ некоторых пациентов октреотид может изменять абсорбцию жиров в кишечнике. На фоне применения октреотида отмечается снижение содержания цианокобаламина (витамина B12) и отклонение от нормы показателей теста всасывания цианокобаламина (тест Шиллинга).\u003Cbr\u003EУ пациентов с дефицитом витамина В12 в анамнезе при применении октреотида рекомендуется контролировать содержание цианокобаламина.\u003Cbr\u003EЕсли на фоне применения октреотида развивается брадикардия, необходимо снизить дозы бета-адреноблокаторов, блокаторов \"медленных\" кальциевых каналов или препаратов, влияющих на водно-электролитный баланс.\u003Cbr\u003EДо назначения октреотида больные должны пройти исходное УЗИ желчного пузыря.\u003Cbr\u003EЕсли камни в желчном пузыре выявлены перед началом лечения, вопрос о применении Октреотида решается индивидуально, в зависимости от соотношения потенциального лечебного эффекта препарата и возможными факторами риска, связанными с наличием камней в желчном пузыре.\u003Cbr\u003EВо время лечения октреотидом следует проводить УЗИ желчного пузыря, с интервалом 6-12 месяцев.\u003Cbr\u003EВедение больных, у которых камни желчного пузыря образуются в процессе лечения октреотидом\u003Cbr\u003Eа) Бессимптомные камни желчного пузыря.\u003Cbr\u003EПрименение октреотида можно прекратить или продолжить - в соответствии с оценкой соотношения польза/риск. В любом случае не требуется никаких других мер, кроме продолжения проведения осмотров, сделав их, при необходимости, более частыми.\u003Cbr\u003Eб) Камни желчного пузыря с клинической симптоматикой.\u003Cbr\u003EПрименение октреотида можно прекратить или продолжить - в соответствии с оценкой соотношения польза/риск. В любом случае больного следует лечить так же, как и в других случаях желчнокаменной болезни с клиническими проявлениями.\u003Cbr\u003EПобочные эффекты со стороны ЖКТ могут быть уменьшены, если инъекции Октреотида делать в промежутках между приемами пищи или перед сном.\u003Cbr\u003EНеобходима коррекция режима дозирования одновременно применяемых диуретиков, бета-адреноблокаторов, блокаторов \"медленных\" кальциевых каналов, инсулина, пероральных гипогликемических средств, глюкагона.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EСахарный диабет, желчнокаменная болезнь."},{"name":"Взаимодействие","value":"Октреотид уменьшает всасывание циклоспорина, замедляет всасывание циметидина.\u003Cbr\u003EНеобходима корректировка доз одновременно применяемых мочегонных средств, бета-адреноблокаторов, блокаторов \"медленных\" кальциевых каналов, инсулина, пероральных гипогликемических препаратов.\u003Cbr\u003EПри одновременном применении Октреотида и бромокриптина биодоступность последнего повышается.\u003Cbr\u003EПрепараты, метаболизирующиеся ферментами системы цитохрома Р450 и имеющие узкий терапевтический диапазон доз (например, хинидин, терфенадин) следует назначать с осторожностью."},{"name":"Регистрационный номер","value":"ЛСР-003582/10"},{"name":"Дата государственной регистрации","value":"19.05.2021"},{"name":"Владелец регистрационного удостоверения","value":"Фармкомпания","transition":{"type":"catalog","params":{"categorySlug":"sistemnye-gormonalnye-preparaty","categoryId":"15756915","navnodeId":"72510","glfilters":["34324371:35649313","7893318:35860830"]}}},{"name":"Изготовитель","value":"Натива"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Октреотид","transition":{"type":"catalog","params":{"categorySlug":"sistemnye-gormonalnye-preparaty","categoryId":"15756915","navnodeId":"72510","glfilters":["17796364:18051646"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"8819632766356791153":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"желудок, кровеносная система, пищеварительная система, поджелудочная железа"},{"name":"Назначение","value":"остановка кровотечения, панкреатит, профилактика кровотечений"},{"name":"Показания к применению","value":"- Профилактика и лечение осложнений после операций на поджелудочной железе и гастродуоденальной зоне;\u003Cbr\u003E - в составе комплексной терапии для остановки кровотечений и профилактики повторного кровотечения из варикозно расширенных вен пищевода у больных с циррозом печени;\u003Cbr\u003E - лечение острого панкреатита;\u003Cbr\u003E - остановка кровотечений при язвенной болезни желудка и 12-перстной кишки."},{"name":"Противопоказания","value":"Повышенная чувствительность к компонентам препарата."},{"name":"Состав","value":"1 мл раствора содержит:\u003Cbr\u003Eактивное вещество: октреотида ацетат (в пересчете на октреотид) 0,050 мг, 0,100 мг и 0,300 мг;\u003Cbr\u003Eвспомогательные вещества: натрия хлорид 9,0 мг, вода для инъекций до 1,0 мл."},{"name":"Действующее вещество","value":"Октреотид"},{"name":"Способ применения и дозы","value":"При лечении острого панкреатита Октреотид вводится п/к в дозе 100 мкг 3 раза/сут в течение 5-7 суток. Возможно назначение до 1200 мкг/сут, подбор дозы основан на определении концентрации амилазы, липазы, воспалительных цитокинов крови.\u003Cbr\u003EДля профилактики осложнений после операций на поджелудочной железе первую дозу Октреотида 100 мкг вводят п/к за 1 час до лапаротомии; затем после операции вводят п/к по 100 мкг 3 раза/сут на протяжении 7 последующих дней.\u003Cbr\u003EДля остановки кровотечения из варикозно расширенных вен пищевода препарат вводят в/в в дозе 25 мкг/ч в виде продолжительных инфузий в течение 5 дней.\u003Cbr\u003EДля остановки кровотечений при язвенной болезни желудка и 12-перстной кишки рекомендуется вводить Октреотид в виде в/в инфузий в дозе 25 мкг/ час в течение 5 дней.\u003Cbr\u003EУ больных пожилого возраста нет необходимости в снижении дозы Октреотида.\u003Cbr\u003EУ пациентов с нарушением функции почек коррекция режима дозирования октреотида не требуется.\u003Cbr\u003EУ пациентов с нарушением функции печени рекомендуется коррекция поддерживающей дозы, т.к. имеются данные об увеличении Т1/2 октреотида у больных циррозом печени.\u003Cbr\u003EОпыт применения октреотида у детей очень ограничен.\u003Cbr\u003EПравила приготовления и введения раствора\u003Cbr\u003EДля уменьшения явлений дискомфорта в месте введения, раствор Октреотида перед введением должен иметь комнатную температуру.\u003Cbr\u003EПри п/к введении препарата следует избегать нескольких инъекций в одно и то же место через короткие интервалы времени. Ампулы с препаратом следует открывать непосредственно перед введением, неиспользованное количество раствора следует уничтожить.\u003Cbr\u003EПри в/в введении следует внимательно осмотреть раствор на предмет прозрачности, наличия частиц, осадка, изменения цвета. Нельзя применять препарат, если он является мутным, содержит частицы, осадок. Октреотид в течение 24 часов сохраняет физическую и химическую стабильность в стерильном 0,9 % растворе натрия хлорида при температуре от 8 до 25 °С. Во избежание микробного загрязнения разведенные растворы следует использовать сразу после приготовления. Если раствор не будет использован сразу, его следует хранить при температуре от 2 до 8 °С вплоть до его применения. Перед использованием раствор следует подержать при комнатной температуре.\u003Cbr\u003EОбщее время между разведением, хранением в холодильнике и окончанием введения раствора не должно превышать 24 ч.\u003Cbr\u003EПри необходимости в/в введения содержимое одной ампулы, содержащей 300 мкг октреотида, должно быть разведено в 60 мл 0,9% раствора натрия хлорида, приготовленный раствор следует вводить в/в капельно. Инфузии повторяют с необходимой частотой в соответствии с рекомендованной длительностью лечения. Октреотид также можно вводить и в более низких концентрациях."},{"name":"Побочные действия","value":"Местные реакции: в месте инъекции возможны боль, ощущение зуда или жжение, краснота и припухлость (обычно проходят в течение 15 минут).\u003Cbr\u003EСо стороны ЖКТ, поджелудочной железы, печени и желчного пузыря: возможны - анорексия, тошнота, рвота, спастические боли в животе, ощущение вздутия живота, избыточное газообразование, жидкий стул, диарея и стеаторея. Хотя выделение жира с калом может возрастать, нет указаний на то, что длительное лечение октреотидом может приводить к нарушению всасывания (мальабсорбции). В редких случаях могут отмечаться явления, напоминающие острую кишечную непроходимость: прогрессирующее вздутие живота, выраженная боль в эпигастральной области, напряжение брюшной стенки.\u003Cbr\u003EДлительное использование октреотида может приводить к образованию камней в желчном пузыре.\u003Cbr\u003EИзвестны отдельные случаи острого гепатита без холестаза (нормализация показателей трансаминаз после отмены октреотида), а также гипербилирубинемии в сочетании с увеличением активности щелочной фосфатазы, гамма-глутамилтрансферазы и др. трансаминаз.\u003Cbr\u003EИмеются отдельные сообщения о редких случаях острого панкреатита, который развивался в первые часы или дни применения октреотида.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: в отдельных случаях - тахикардия, брадикардия.\u003Cbr\u003EСо стороны обмена веществ: возможно нарушение толерантности к глюкозе после приема пищи (октреотид оказывает подавляющее Действие на образование ГР, глюкагона и инсулина), гипогликемия; в редких случаях при длительном лечении возможно развитие персистирующей гипергликемии.\u003Cbr\u003EПрочие: редко - аллергические реакции, алопеция; в отдельных случаях - анафилактические реакции."},{"name":"Фармакологическое действие","value":"Октреотид - синтетический октапептид, производное естественного гормона соматостатина, обладает сходными с ним фармакологическими эффектами, но со значительно большей продолжительностью действия. Октреотид подавляет как патологически повышенную секрецию гормона роста (ГР), так и вызываемую аргинином, физической нагрузкой и инсулиновой гипогликемией. Препарат подавляет секрецию серотонина, гастрина, инсулина и глюкагона и других пептидов, продуцируемых в гастроэнтеропанкреатической эндокринной системе. У больных, которым проводятся операции на поджелудочной железе, применение октреотида во время операции и после нее снижает частоту типичных послеоперационных осложнений (острого послеоперационного панкреатита, панкреатических свищей, абсцессов, сепсиса).\u003Cbr\u003EПри кровотечениях из варикозно расширенных вен пищевода и желудка у больных циррозом печени применение октреотида в составе комплексной терапии приводит к эффективной остановке кровотечения, профилактике раннего повторного кровотечения и улучшению выживаемости. Механизм действия октреотида связан с уменьшением органного кровотока посредством подавления вазоактивных гормонов (вазоактивного интестинального пептида, глюкагона)."},{"name":"Фармакологическая группа","value":"соматостатина аналог синтетический"},{"name":"Форма выпуска","value":"раствор для инъекций и инфузий"},{"name":"Способ применения/введения","value":"парентеральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте при температуре не выше 25 °С. Не замораживать.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Известно, что введение октреотида в дозе до 2000 мкг в виде п/к инъекции 3 раза в течение нескольких месяцев переносилось хорошо.\u003Cbr\u003EМаксимальная разовая доза при в/в болюсном введении взрослому пациенту составляла 1000 мкг. При этом отмечались такие симптомы, как снижение частоты сердечных сокращений, \"приливы\" крови к лицу, абдоминальная боль спастического характера, диарея, тошнота, ощущение пустоты в желудке. Все эти симптомы разрешились в течение 24 часов с момента введения препарата.\u003Cbr\u003EОдному пациенту по ошибке методом длительной инфузии была введена избыточная доза октреотида 250 мкг/ч (вместо 25 мкг/ч), что не сопровождалось побочными эффектами.\u003Cbr\u003EПри острой передозировке не было отмечено каких-либо опасных для жизни реакций.\u003Cbr\u003EЛечение: симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Адекватных и контролируемых исследований не проводилось. Применение во время беременности и в период лактации только по абсолютным показаниям, с учетом соотношения риск/польза, т.е. когда предполагаемая польза для матери превышает предполагаемый риск для плода или грудного ребенка."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"На сегодняшний день не имеется данных о влиянии октреотида на способность водить автомобиль и работать с механизмами."},{"name":"Особые указания","value":"У больных сахарным диабетом 1 типа (получающих инсулин), октреотид может снижать потребность в инсулине. У пациентов без нарушения углеводного обмена и больных сахарным диабетом 2 типа введение препарата может приводить к постпрандиальной гликемии. Пациентам с сахарным диабетом на фоне гипогликемической терапии рекомендуется проводить контроль концентрации глюкозы в крови.\u003Cbr\u003EУ некоторых пациентов октреотид может изменять абсорбцию жиров в кишечнике. На фоне применения октреотида отмечается снижение содержания цианокобаламина (витамина B12) и отклонение от нормы показателей теста всасывания цианокобаламина (тест Шиллинга).\u003Cbr\u003EУ пациентов с дефицитом витамина В12 в анамнезе при применении октреотида рекомендуется контролировать содержание цианокобаламина.\u003Cbr\u003EЕсли на фоне применения октреотида развивается брадикардия, необходимо снизить дозы бета-адреноблокаторов, блокаторов \"медленных\" кальциевых каналов или препаратов, влияющих на водно-электролитный баланс.\u003Cbr\u003EДо назначения октреотида больные должны пройти исходное УЗИ желчного пузыря.\u003Cbr\u003EЕсли камни в желчном пузыре выявлены перед началом лечения, вопрос о применении Октреотида решается индивидуально, в зависимости от соотношения потенциального лечебного эффекта препарата и возможными факторами риска, связанными с наличием камней в желчном пузыре.\u003Cbr\u003EВо время лечения октреотидом следует проводить УЗИ желчного пузыря, с интервалом 6-12 месяцев.\u003Cbr\u003EВедение больных, у которых камни желчного пузыря образуются в процессе лечения октреотидом\u003Cbr\u003Eа) Бессимптомные камни желчного пузыря.\u003Cbr\u003EПрименение октреотида можно прекратить или продолжить - в соответствии с оценкой соотношения польза/риск. В любом случае не требуется никаких других мер, кроме продолжения проведения осмотров, сделав их, при необходимости, более частыми.\u003Cbr\u003Eб) Камни желчного пузыря с клинической симптоматикой.\u003Cbr\u003EПрименение октреотида можно прекратить или продолжить - в соответствии с оценкой соотношения польза/риск. В любом случае больного следует лечить так же, как и в других случаях желчнокаменной болезни с клиническими проявлениями.\u003Cbr\u003EПобочные эффекты со стороны ЖКТ могут быть уменьшены, если инъекции Октреотида делать в промежутках между приемами пищи или перед сном.\u003Cbr\u003EНеобходима коррекция режима дозирования одновременно применяемых диуретиков, бета-адреноблокаторов, блокаторов \"медленных\" кальциевых каналов, инсулина, пероральных гипогликемических средств, глюкагона.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EСахарный диабет, желчнокаменная болезнь."},{"name":"Взаимодействие","value":"Октреотид уменьшает всасывание циклоспорина, замедляет всасывание циметидина.\u003Cbr\u003EНеобходима корректировка доз одновременно применяемых мочегонных средств, бета-адреноблокаторов, блокаторов \"медленных\" кальциевых каналов, инсулина, пероральных гипогликемических препаратов.\u003Cbr\u003EПри одновременном применении Октреотида и бромокриптина биодоступность последнего повышается.\u003Cbr\u003EПрепараты, метаболизирующиеся ферментами системы цитохрома Р450 и имеющие узкий терапевтический диапазон доз (например, хинидин, терфенадин) следует назначать с осторожностью."},{"name":"Регистрационный номер","value":"ЛСР-003582/10"},{"name":"Дата государственной регистрации","value":"19.05.2021"},{"name":"Владелец регистрационного удостоверения","value":"Фармкомпания"},{"name":"Изготовитель","value":"Натива"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Октреотид"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_1997516650788470157"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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374 ₽

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  • Октреотид р-р для в/в введ. введ. и п/к введ., 100 мкг/мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gcinlqwm7cr/toggleWishlist":{"skuId":"186487581","productId":1778176975,"offerId":"by09bPiSWwWJHKUS_Jw71Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpIalj/jVoKdVEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIz6fzzwYQnab2WBiW49AHIPPcwQc=","sign":"TaL3Hrhvj4CaTAZI+4rM79BgrZ1qB61G865ftwAGyrA="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-gcinlqwm7cr/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Октреотид р-р для в/в введ. введ. и п/к введ., 100 мкг/мл, 10 шт.

    Рейтинг товара: 4.4 из 5
    на основе 10 оценок
    Цена 1 239 ₽
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  • Октреотид р-р для в/в введ. введ. и п/к, 100 мкг/мл, 1 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-io2jxt4e3q/toggleWishlist":{"skuId":"227830339","productId":1778176992,"offerId":"wNcUnkoOXrqwTeoaqhc3Sw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpIalj/jVoKdVEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI4KfzzwYQw9TRbBiW49AHIPPcwQc=","sign":"t+jqxUr7V11GI/4z0JAj4eU30FeUWEUFhnACAht/8dQ="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-io2jxt4e3q/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Октреотид р-р для в/в введ. введ. и п/к, 100 мкг/мл, 1 мл, 5 шт.

    Рейтинг товара: 4 из 5
    на основе 9 оценок
    Цена 634 ₽
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  • Сандостатин р-р для в/в введ. и п/к введ., 0.05 мг/мл, 1 мл, 5 шт.
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    Сандостатин р-р для в/в введ. и п/к введ., 0.05 мг/мл, 1 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 382 ₽
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  • Октретекс р-р д/ин.ф. и п/к введ., 0.1 мг, 1 мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kekbkxk293/toggleWishlist":{"skuId":"228054920","productId":1436732422,"offerId":"JOe12e6uZYgdkeI4Cwa5Og","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpIalj/jVoKdVEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIhpiLrQUQiK/fbBig6pAHIPPcwQc=","sign":"HWt6BvZc9RbfZB2DDG3ySGhbDh7Q7CG4isialmev46U="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kekbkxk293/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Октретекс р-р д/ин.ф. и п/к введ., 0.1 мг, 1 мл, 10 шт.

    Рейтинг товара: 3 из 5
    на основе 2 оценки
    Цена 1 246 ₽
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  • Антиква Рапид таб. дисперг., 60 мкг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-aqcwjjoqzyo/toggleWishlist":{"skuId":"663697004","productId":998360073,"offerId":"Ufl-SGMsUsJlRsp18McVSg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpIalj/jVoKdVEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIiYiH3AMQ7Oy8vAIYrsLZByDz3MEH","sign":"8fOQXgXh8Vvg8Xttv0DXZQMdFYzsU1DXBLUnSSYt+T0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-aqcwjjoqzyo/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Антиква Рапид таб. дисперг., 60 мкг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 8 оценок
    Цена 1 298 ₽
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  • Ноурем таб., 0.1 мг, 30 шт.
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    Ноурем таб., 0.1 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 8 оценок
    Цена 709 ₽
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  • Десмопрессин таб., 0.1 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8vpwxjvayum/toggleWishlist":{"skuId":"228044228","productId":1401075681,"offerId":"ufKb7KQm20Ry9iCH6LmEBA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpIalj/jVoKdVEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI4e+KnAUQxNvebBiEqbIIIPPcwQc=","sign":"ZDcDy2oyqbSrCJnh0NyC8e/glF0dohhIcrnWX6H3g5c="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8vpwxjvayum/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Десмопрессин таб., 0.1 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 791 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8vpwxjvayum/addToCartButton":{"offerId":"ufKb7KQm20Ry9iCH6LmEBA","skuId":"228044228","pendingCartItem":{"productId":1401075681,"offerId":"ufKb7KQm20Ry9iCH6LmEBA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMnMCP4h2oY8ikaBNqegDcA2v1ZwRqFx57xsn4gRo13NthDc_zbqzFYgVGWmvrr6nBueid6TXBEXt_hQuMAGYIKI4dhD2NZO3Kdi9SAlEVOL2nVcE56DcK8fqHWRS5RLs2myyVEgnzYNnkW0_l8Zv7bSm3bSmLW4pJ1onhZWHUMQIVQotK_hfqmIHtqcMJ_BeGw,,","feeShow":"OTNDnItfwRMjN9MRHuEMMnMCP4h2oY8ikaBNqegDcA2v1ZwRqFx57xsn4gRo13NthDc_zbqzFYgVGWmvrr6nBueid6TXBEXt_hQuMAGYIKI4dhD2NZO3Kdi9SAlEVOL2nVcE56DcK8fqHWRS5RLs2myyVEgnzYNnkW0_l8Zv7bSm3bSmLW4pJ1onhZWHUMQIVQotK_hfqmIHtqcMJ_BeGw,,","skuId":"228044228","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"791","currency":"RUR"},"hid":"15756915","name":"Десмопрессин таб., 0.1 мг, 30 шт.","label":"6r03hn7th8v","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4303516,"key":"img_id6459380635333965707.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCkDTJdUMBhxLcrhkF1w97S0Dq4px-uGWx_On5fPKZgdLWQfj6AAujfTC6FeIhbdL45MY-gEZaDsim0jRoDaVFEJ0kJcmgHgaixMhhaOVYngN8dchzBIlhiAnXEiyTPSOF9XO_GlM6oDGLG-lYQ9RqqNUp8JE5KLAzUeHQ27x7vyjHzus4_NpVAz3nqQSlyuY5zIGYyHhmhmqLXxQu7-j6w9quThondLaj2rpaF0cgE-elOttnkPEhI1MEF4XlrcMJr7TQ3kqWzS6btitt5gnofGWOdjyTHMikvRq7n8_w4YngKwji0_UQBSyOnRH0pdcbUU0Xj3fyUGqtBsh2cwN3CmIMIUOOQyPRTClU7OXUV8U8TTcywINOeJVEQwBMjF1f94gaWl-qxup9MqvC8SjpGfyTD6Pta9FoKAYPTp6kYvWXDmOWFQI6MeWIQeKWq8VsLGkhA46wgxrMxIke9sAwysEzsm_fS8BmYhvp7j76IS29shaoeYEepR09ay78N8r1PypdGxUO38WSbsOvlsbrb9vuuNX9w8aBYPoPz2y-yPT7YVkvLHJdY-EVTgDlVQDdrjRoOB7P_3LBrTIWkAc8GkpHudbleaD1Znev_b15dpZN6Ca5Cxuh-6PX_HyIVEMjUe3DVB1G4PXrNmK0vQ19IEwiTdPs2lrG_qROewWVL3zFePHPlsdy30c_unX3AYpUegdFpX1ry1M5fH2Rdl4WiD32qKedvUGm_CxWoasGmPORIBlusG-sT7lRdQbyOngXpbpWLsPhLDtvnyXPxL3j5jIqhWtjVTs1nWAw2lL-EPB3rJt72-ROobewxiWpycq7KqC8MADjyQehtxKtHcOf-pL7A_vqOY309LTTQMsfIdcJpORjQfJC7zg7f9BEZgUkm3r3ZFNGY6Uu_GwKTqWiCNk05UAwbhjch1Iv-xCNw35rLbjPQFd_7qTmiUiMKkhHqyaibb-53sr5b_qTeoUVhrbSM6lGVcj-_tcqpkJdygkRA31JCt4rzVcskrRt4d6-1Vif5jVefEAgSoSVPM01eYhEYwKa-RwTJujDPaaf9wmIT2ez3Scp8FAO_pe_-W82V2TDvTZojUzCxzJmJQVTwfIH1EX5HKZf1jbD8tRIBZr-S0v7QZHxlSgZDOowmO-PKfYIRePXqmoy2wUV92Is3XKWJr20pHjuiOwyJKcqrXdT2CH_JR6hMmWBkWqB6IGVPXBZ9Y_b-kJHr1IvOguNiZTttGxvyB8wxfJsWxFifaqqsPCvGBaNmZKXsRl6SwvKEQ7eY3U5e5KBf-9y7Z9Zyu3S-utNcRZAPBSs0zd3Rc6gmWhT7AFGqZuUiEIlP-nI0iAoPjMcPzETizkrvh0DZ4CxHj-cW0V7EoTfeUhq3BfuQwDm1cMHS_Um-y7r9HnMZMm7VPMRxE2IIdMRBmTfl60zDVTqnEpNz9-09ErbRtTMda7_y0R_n94Kb_hjkPZm7fFWgwupvTKEN22Coxr-MwJ1SlShDhYlg2WKJxLxy-OiSO9OAYRDrP0Ea9ZZp2iUdktySwLija5RLDIekwdA5TpQ4tQoB4TYpCOXRfZ6xpMttRCMYkwILMr-QMBKYLhj4RxfMbWVcspm15NNY5BP0A6buQX9YfjH5rgA6pILm2BfwzHEb4R6Fnc-dKkFwFdRWpTgUHzMp27TVA2XpP_2X4oOdsqpcR5FkKlA60Z9p5GEE0yJtKrPbg213ERdPY7agsVIel5DKxQAVnlIZUlcRpiyk_ynBOiG3mlcIOjhF0YY0AFtxieXhZGVfaRm2dgUylhfbUZN0cRgL5vcPg2QrO89ZAD1IZVn46gLesGdYuOs-000tbMc83E-JdXbroSnU56uSiPgEtS1OPOcVuCgIxKwdbHPvzvRx-dQXHtDjK_zMOFIkf1djL5iaBZtnDZvXRNvj02UMmSG6jDhaj50FLJxHAi8HZfgJ2JyuC9fqCObyQcnE2fCUoa1dbNFSuxko4IYnRTuMI6nSF4O66tnko-MQOOuIGRWV0j8hSLRmv6qnyTEgHI_Hq_9rK821Atb0upCqxSK6-CGrK7dPVBwYa_KbnzkrmOUIBo6cjVmc2JZfd7SB8U2Fb4E1u1eWPDAFdh_ICGnPb5H9JMc9C-BMO6KZUHxVMOm-2GXTYblQpqH3fqKiq_kUaGzzMrVUi6vU6YwIOs4Q7_4Vuv7bg-P9ou30bg9-qKo-ZD52La_1hFTTH6gxCorC63mhUKe3mkD_5C1Kg8BQbAL5qc57AeR7PdDeDhMJ0DlQxR8IChCdd4ovFytk95A8So_uBoMC3bdTbMlf3ITudrT-IL2Ec9BoOyyhj1WKGjdFYzNj_HoRvwvjJM2Xhc7r-olqAw6WvLvHnegEYoVeicwCgbSck6ipI_lwLq1MuUuoxL20u6sBpOC0OvOQOpGakbpKQfPlXdgjawTLdQd8aJxslouw8OSw2Tn1w8bjwkd3WOeKikFkgM8spt1uT08NafnGylMoLOb2_-V51OWKN_vQS1TioEdzIJHKGAk45CWxnz0h1hvDv1KpmIBSMKkOYi3UdBRbsFu7AhC06uj1oYRBcXLwHiIFs5Xb-qVkdSYqwHqjr8xLDuGlNs1y2Rza9FykPRJ1g9AlRnutxeGxkh3NJFJ-Nc5Um7Opglufv8Iak0aw557QulXlbPBcG-_PsR6p96dtNCa_Wf5S_b2eNMEb9mC9_j_taTwyV8_gWnrQSrvrWMfBAhkct4upvVIfYiYBZDWYUGC0pYaGGqIQzAF1wwXFOfLAhAIGPvnOtfOTKmRO5ok5LEpIl7kBynXIIvwFY8XV5K79-9LR8zhTzvy3PiYumVeVXR6D2VDMdOyCLztlM7hOgArvT5FrmJGZfV5Oi6ltu0FPhVNZZsCtV5DsWeoRYDaItPlp0ruyhGpv1evUJpI1EmGRq1DMQmlt1OHQwf8_FTh4GaoA5nvYvC8978oer1rMotvQMh7MDH-aqH1HzoErBauWE2vWLoFDCBUuYqn7LkcbhDyLfKSk-OklN9CB_d_pJVRKUXSn9iJWFOrdYo2mtt9ngRKVFp6XZ2UYgOWTun6Ney6ANT2gVr3qX0sqnjxdW3im6z4zOqN18rZwfI0W1T5mvGoLdq0W4ikPWMuIqv4XDVOlwTlPJ2vqcSlDX9mNd7CXcZyXcSAFVA7qemJKrLtRmblTaCkyOF6TiHH2hzNNkDVPerb0nn8RY4TpiacuUXeil4aMk58XmxTfXw0h5vZJKPdF776Kzs9cX8tgEkT3Mi_vjHQdJonNOO2BQ4vKM6569IWDoz7gqI0AnZ_ucyNZ9qNyuGlVUwyNOgr3IaZWzCHPM3Sqrv_ez-K2PMofytj8X3UyDxl4f84Oc0BAfJrdhxyEovEwb5rE6ZZsjyF406PUT862CY5jdG24dLVxI,/b64e=1/sign=69f51a8b1a252e4cd568b1e52e841ac5/keyno=MARKET_1/*","showUid":"17177414265475747076306008","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpIalj/jVoKdVEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI4e+KnAUQxNvebBiEqbIIIPPcwQc=","sign":"ZDcDy2oyqbSrCJnh0NyC8e/glF0dohhIcrnWX6H3g5c="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpIalj/jVoKdVEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI4e+KnAUQxNvebBiEqbIIIPPcwQc=","sign":"ZDcDy2oyqbSrCJnh0NyC8e/glF0dohhIcrnWX6H3g5c="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8vpwxjvayum/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Зифлукорт таб., 0.1 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9wwkozj1pqo/toggleWishlist":{"skuId":"102075403730","productId":1886405925,"offerId":"74mjR8Jxu9Kdvw363n5pug","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpIalj/jVoKdVEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIpYrBgwcQ0pusofwCGOyjswgg89zBBw==","sign":"sxFyT1M6iqvTimu2MbOPgMQ1OEuFPWeyanVVJaj2FjY="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9wwkozj1pqo/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Зифлукорт таб., 0.1 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 4 оценки
    Цена 513 ₽
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  • Минирин таб., 0.1 мг, 30 шт.
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    Минирин таб., 0.1 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 789 ₽
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  • Октреотид-депо лиоф. д/приг. сусп. для в/м введ. пролонг. фл., 20 мг
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    Октреотид-депо лиоф. д/приг. сусп. для в/м введ. пролонг. фл., 20 мг

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 19 606 ₽
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Инструкция

Показания к применению

- Профилактика и лечение осложнений после операций на поджелудочной железе и гастродуоденальной зоне;
- в составе комплексной терапии для остановки кровотечений и профилактики повторного кровотечения из варикозно расширенных вен пищевода у больных с циррозом печени;
- лечение острого панкреатита;
- остановка кровотечений при язвенной болезни желудка и 12-перстной кишки.

Противопоказания

Повышенная чувствительность к компонентам препарата.

Способ применения и дозы

При лечении острого панкреатита Октреотид вводится п/к в дозе 100 мкг 3 раза/сут в течение 5-7 суток. Возможно назначение до 1200 мкг/сут, подбор дозы основан на определении концентрации амилазы, липазы, воспалительных цитокинов крови.
Для профилактики осложнений после операций на поджелудочной железе первую дозу Октреотида 100 мкг вводят п/к за 1 час до лапаротомии; затем после операции вводят п/к по 100 мкг 3 раза/сут на протяжении 7 последующих дней.
Для остановки кровотечения из варикозно расширенных вен пищевода препарат вводят в/в в дозе 25 мкг/ч в виде продолжительных инфузий в течение 5 дней.
Для остановки кровотечений при язвенной болезни желудка и 12-перстной кишки рекомендуется вводить Октреотид в виде в/в инфузий в дозе 25 мкг/ час в течение 5 дней.
У больных пожилого возраста нет необходимости в снижении дозы Октреотида.
У пациентов с нарушением функции почек коррекция режима дозирования октреотида не требуется.
У пациентов с нарушением функции печени рекомендуется коррекция поддерживающей дозы, т.к. имеются данные об увеличении Т1/2 октреотида у больных циррозом печени.
Опыт применения октреотида у детей очень ограничен.
Правила приготовления и введения раствора
Для уменьшения явлений дискомфорта в месте введения, раствор Октреотида перед введением должен иметь комнатную температуру.
При п/к введении препарата следует избегать нескольких инъекций в одно и то же место через короткие интервалы времени. Ампулы с препаратом следует открывать непосредственно перед введением, неиспользованное количество раствора следует уничтожить.
При в/в введении следует внимательно осмотреть раствор на предмет прозрачности, наличия частиц, осадка, изменения цвета. Нельзя применять препарат, если он является мутным, содержит частицы, осадок. Октреотид в течение 24 часов сохраняет физическую и химическую стабильность в стерильном 0,9 % растворе натрия хлорида при температуре от 8 до 25 °С. Во избежание микробного загрязнения разведенные растворы следует использовать сразу после приготовления. Если раствор не будет использован сразу, его следует хранить при температуре от 2 до 8 °С вплоть до его применения. Перед использованием раствор следует подержать при комнатной температуре.
Общее время между разведением, хранением в холодильнике и окончанием введения раствора не должно превышать 24 ч.
При необходимости в/в введения содержимое одной ампулы, содержащей 300 мкг октреотида, должно быть разведено в 60 мл 0,9% раствора натрия хлорида, приготовленный раствор следует вводить в/в капельно. Инфузии повторяют с необходимой частотой в соответствии с рекомендованной длительностью лечения. Октреотид также можно вводить и в более низких концентрациях.
Полная инструкция
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Октреотид р-р для в/в и п/к введ. амп.
Октреотид р-р для в/в и п/к введ. амп., 50 мкг/мл, 1 мл, 5 шт.
5.0
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1 вопрос
Инструкция

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