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Описание

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Пульмикорт сусп. д/инг., 0.5 мг/мл, 2 мл, 20 шт.

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4.8
(62)
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Дозировка: 0.5 мг/мл

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Коротко о товаре

Артикул Маркета
34644372
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 месяцев
Инструкция
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В том случае, если рекомендуемая доза не превышает 1 мг/сутки, всю дозу препарата можно принять за один раз (единовременно). В случае приема более высокой дозы рекомендуется её разделить на два приёма.\u003Cbr\u003EРекомендуемая начальная доза:\u003Cbr\u003EДети от 6 месяцев и старше: 0,25-0,5 мг в сутки. При необходимости доза может быть увеличена до 1 мг/сутки.\u003Cbr\u003EВзрослые/пожилые пациенты: 1-2 мг в сутки.\u003Cbr\u003EДоза при поддерживающем лечении:\u003Cbr\u003EДети от 6 месяцев и старше: 0,25-2 мг в сутки.\u003Cbr\u003EВзрослые: 0,5-4 мг в сутки. В случае тяжелых, обострений доза может быть увеличена.\u003Cbr\u003EДля всех пациентов желательно определить минимальную эффективную поддерживающую дозу.\u003Cbr\u003EВ случае необходимости достижения дополнительного терапевтического эффекта можно рекомендовать увеличение суточной дозы (до 1 мг/сутки) Пульмикорта вместо комбинации препарата с пероральными глюкокортикостероидами; благодаря более низкому риску развития системных эффектов. \u003Cbr\u003EПациенты, получающие пероральные глюкокортикостероиды \u003Cbr\u003EОтмену пероральных глюкокортикостероидов необходимо начинать на фоне стабильного состояния здоровья пациента. В течение 10 дней необходимо принимать высокую дозу Пульмикорта на фоне приема пероральных глюкокортикостероидов в привычной дозе. В дальнейшем в течение месяца следует постепенно снижать дозу пероральных глюкокортикостероидов (например, по 2,5 мг преднизолона или его аналога) до минимальной эффективной дозы. Во многих случаях удаётся полностью отказаться от приёма пероральных глюкокортикостероидов. Поскольку Пульмикорт, применяемый в виде суспензии с помощью небулайзера, попадает в легкие при вдохе важно проинструктировать пациента вдыхать препарат через мундштук небулайзера спокойно и ровно.\u003Cbr\u003EНет данных о применении будесонида у пациентов с почечной недостаточностью или нарушением функции печени. Принимая во внимание тот факт, что будесонид выводится путем биотрансформации в печени, можно ожидать увеличения длительности действия препарата у пациентов с выраженным циррозом печени.\u003Cbr\u003EСтенозирующий ларинготрахеит (ложный круп)\u003Cbr\u003EДети от 6 месяцев и старше: 2 мг в сутки.\u003Cbr\u003EДозу препарата можно принять за один раз (единовременно) или разделить ее на два приема по 1 мг с интервалом в 30 мин.\u003Cbr\u003EНарушение функции печени или почек\u003Cbr\u003EНет данных о применении будесонида у пациентов с нарушением функции печени или почек. Принимая во внимание тот факт, что будесонид выводится путем биотрансформации в печени, можно ожидать увеличения экспозиции препарата у пациентов с выраженным циррозом печени.\u003Cbr\u003E"},{"name":"Побочные действия","value":"До 10% пациентов, принимающих препарат, могут испытывать следующие побочные эффекты:\u003Cbr\u003EЧасто (\u003E1/100)\u003Cbr\u003EДыхательные пути: кандидоз ротоглотки, раздражение слизистой оболочки глотки, кашель, охриплость голоса, сухость во рту.\u003Cbr\u003EРедко (\u003C1/1000)\u003Cbr\u003EАллергические реакции: ангионевротический отек.\u003Cbr\u003EЦНС: головная боль.\u003Cbr\u003EДерматологические реакции: крапивница, сыпь, контактный дерматит.\u003Cbr\u003EДыхательные пути: бронхоспазм.\u003Cbr\u003EСо стороны ЦНС: возможны нервозность, возбудимость, депрессия, нарушения поведения.\u003Cbr\u003EВ отдельных случаях могут возникать симптомы, вызванные системным действием ГКС (включая гипофункцию надпочечников).\u003Cbr\u003EПрочие: редко - появление кровоподтеков на коже, раздражение кожи лица при использовании небулайзера с маской."},{"name":"Фармакологическое действие","value":"Будесонид, ингаляционный глюкокортикостероид, в рекомендованных дозах оказывает противовоспалительное действие в бронхах, снижая выраженность симптомов и частоту обострений бронхиальной астмы с меньшей частотой побочных эффектов, чем при использовании системных глюкокортикостероидов. Уменьшает выраженность отека слизистой бронхов, продукцию слизи, образование мокроты и гиперреактивность дыхательных путей. Хорошо переносится при длительном лечении, не обладает минералокортикостероидной активностью.\u003Cbr\u003EВремя начала терапевтического эффекта после ингаляции одной дозы препарата составляет несколько часов. Максимальный терапевтический эффект достигается через 1-2 недели после лечения. Будесонид оказывает профилактическое действие на течение бронхиальной астмы и не влияет на острые проявления заболевания.\u003Cbr\u003EПоказано дозозависимое воздействие на содержание кортизола в плазме и моче на фоне приёма Пульмикорта. В рекомендованных дозах препарат оказывает значительно меньшее влияние на надпочечную функцию, чем преднизолон в дозе 10 мг, как было показано в АКТГ тестах."},{"name":"Фармакологическая группа","value":"глюкокортикостероид для местного применения"},{"name":"Форма выпуска","value":"суспензия"},{"name":"Способ применения/введения","value":"ингалятивный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["35947170:36763738"]}}},{"name":"Минимальный возраст применения","value":"от 6 месяцев"},{"name":"Условия хранения","value":"При температуре ниже 30°С. Хранить в недоступном для детей месте. Препарат в контейнерах должен быть использован в течение 3 месяцев после вскрытия конверта. Открытый контейнер должен быть использован в течение 12 часов. Контейнеры следует хранить в конверте для защиты их от света."},{"name":"Передозировка","value":"При острой передозировке клинических проявлений не возникает. При длительном использовании препарата в дозах, значительно превышающих рекомендуемые, может развиться системный глюкокортикостероидный эффект в виде гиперкортицизма и подавления функции надпочечников."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность: наблюдение за беременными женщинами, принимавшими будесонид, не выявило аномалий развития у плода, тем не менее нельзя полностью исключить риск их развития, поэтому во время беременности в связи с возможностью ухудшения течения бронхиальной астмы следует использовать минимальную эффективную дозу будесонида.\u003Cbr\u003EЛактация: Будесонид проникает в грудное молоко, однако при применении Пульмикорта в терапевтических дозах воздействия на ребенка не отмечено. Пульмикорт может применяться во время грудного кормления."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Пульмикорт не оказывает влияния на способность управлять автомобилем или другими механизмами."},{"name":"Особые указания","value":"Для сведения к минимуму риска грибкового поражения ротоглотки следует проинструктировать пациента о необходимости тщательно полоскать рот водой после каждой ингаляции препарата.\u003Cbr\u003EСледует избегать совместного назначения будесонида с кетоконазолом, итраконазолом или другими потенциальными ингибиторами CYP3A4. В случае, если будесонид и кетоконазол или другие потенциальные ингибиторы CYP3A4 были назначены, следует увеличить время между приемом препаратов до максимально возможного.\u003Cbr\u003EИз-за возможного риска ослабления функции надпочечников особое внимание необходимо уделять пациентам, которые переводятся с пероральных глюкокортикостероидов на приём Пульмикорта. Также особое внимание следует уделять пациентам, принимавшим высокие дозы глюкокортикостероидов, или длительно получавшим максимально высокие рекомендованные дозы ингаляционных глюкокортикостероидов. В стрессовых ситуациях у таких пациентов могут проявиться признаки и симптомы надпочечниковой недостаточности. При стрессах или в случаях хирургического вмешательства рекомендуется проводить дополнительную терапию системными глюкокортикостероидами. Особое внимание необходимо уделять пациентам, которые переводятся с системных на ингаляционные глюкокортикостероиды (Пульмикорт) или в случае, когда можно ожидать нарушение гипофизарно-надпочечниковой функции. У таких пациентов следует с особой осторожностью снижать дозу системных глюкокортикостероидов и контролировать гипоталамо-гипофизарно-надпочечниковую функцию. Также пациентам может потребоваться добавление пероральных глюкокортикостероидов в период стрессовых ситуаций, таких как травма, хирургическое вмешательство и т.д.\u003Cbr\u003EПри переходе с пероральных глюкокортикостероидов на Пульмикорт пациенты могут почувствовать ранее наблюдавшиеся симптомы, такие как мышечные боли или боли в суставах. В таких случаях может понадобиться временное увеличение дозы пероральных глюкокортикостероидов. В редких случаях могут наблюдаться такие симптомы как чувство усталости, головная боль, тошнота и рвота, указывающие на системную недостаточность глюкокортикостероидов.\u003Cbr\u003EЗамена пероральных глюкокортикостероидов на ингаляционные иногда приводит к проявлению сопутствующей аллергии, например, ринита и экземы, которые ранее купировались системными препаратами.\u003Cbr\u003EУ детей и подростков, получающих лечение глюкокортикостероидами (независимо от способа доставки) в течение продолжительного периода, рекомендуется регулярно контролировать показатели роста. При назначении глюкокортикостероидов следует принимать во внимание соотношение пользы применения препарата и возможного риска замедления роста.\u003Cbr\u003EПрименение будесонида в дозе до 400 мкг в сутки у детей старше 3-х лет не приводило к возникновению системных эффектов. Биохимические признаки системного эффекта препарата могут встречаться при приёме препарата в дозе от 400 до 800 мкг в сутки. При превышении дозы 800 мкг в сутки системные эффекты препарата встречаются часто. Применение глюкокортикостероидов для лечения бронхиальной астмы может вызывать нарушение роста. Результаты наблюдений за детьми и подростками, получавшими будесонид в течение длительного периода (до 11 лет), показали, что рост пациентов достигает ожидаемых нормативных показателей для взрослых.\u003Cbr\u003EТерапия ингаляционным будесонид ом 1 или 2 раза в сутки показала эффективность для профилактики бронхиальной астмы физического усилия.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EТребуется более тщательное наблюдение за больными: у пациентов с грибковыми, вирусными, бактериальными инфекциями органов дыхания, циррозом печени; при назначений следует принимать во внимание возможное проявление системного действия глюкокортикостероидов."},{"name":"Взаимодействие","value":"Не наблюдалось взаимодействия будесонида с другими препаратами, используемыми при лечении бронхиальной астмы.\u003Cbr\u003EКетоконазол (200 мг один раз в сутки) повышает плазменную концентрацию перорального будесонида (3 мг один раз в сутки) в среднем в 6 раз при совместном приёме. При приеме кетоконазола через 12 часов после приёма будесонида концентрация последнего в плазме крови увеличивалась в среднем в 3 раза. Информация о подобном взаимодействии при приёме будесонида в виде ингаляции отсутствует, однако предполагается, что и в этом случае следует ожидать увеличение концентрации будесонида в плазме крови. В случае необходимости приема кетоконазола и будесонида следует увеличить время между приёмом препаратов до максимально возможного. Также следует рассмотреть возможность снижения дозы будесонида. Другой потенциальный ингибитор CYP3A4, например, итраконазол, также значительно повышает плазменную концентрацию будесонида. Предварительная ингаляция бета-адреностимуляторов расширяет бронхи, улучшает поступление будесонида в дыхательные пути и усиливает его терапевтический эффект. Фенобарбитал, фенитоин, рифампицин снижают эффективность (индукция ферментов микросомального окисления) будесонида.\u003Cbr\u003EМетандростенолон, эстрогены усиливают действие будесонида."},{"name":"Регистрационный номер","value":"П N013826/01"},{"name":"Дата государственной регистрации","value":"25.03.2021"},{"name":"Владелец регистрационного удостоверения","value":"AstraZeneca","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["34324371:35649313","7893318:16002703"]}}},{"name":"Изготовитель","value":"AstraZeneca"},{"name":"Фасовщик","value":"AstraZeneca"},{"name":"Страна бренда","value":"Швеция"},{"name":"Страна-производитель","value":"Швеция"},{"name":"Название препарата","value":"Пульмикорт","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["17796364:18053245"]}}},{"name":"Срок годности","value":"23 мес."}]}},"fullSpecsGrouped":{"1819677480434982959":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"дыхательная система"},{"name":"Назначение","value":"бронхиальная астма, хроническая обструктивная болезнь легких"},{"name":"Показания к применению","value":"- Бронхиальная астма, требующая поддерживающей терапии глюкокортикостероидами. \u003Cbr\u003E- Хроническая обструктивная болезнь легких (ХОБЛ) \u003Cbr\u003EСтенозирующий ларинготрахеит (ложный круп)."},{"name":"Противопоказания","value":"- Повышенная чувствительность к будесониду.\u003Cbr\u003E- Детский возраст до 6 месяцев."},{"name":"Состав","value":"В 1 мл суспензии содержится: \u003Cbr\u003EАктивный ингредиент: будесонид (будесонид микронизированный) 0,25 мг. \u003Cbr\u003EВспомогательные ингредиенты: натрия хлорид 8,5 мг, натрия цитрат 0,5 мг, эдетат динатрия (натриевая соль этилендиаминтетрауксусной кислоты (двухзамещенная) (динатриевая соль ЭДТА)) 0,1 мг, полисорбат 80 0,2 мг, лимонная кислота (безводная) 0,28 мг, вода очищенная."},{"name":"Действующее вещество","value":"Будесонид"},{"name":"Способ применения и дозы","value":"Доза препарата подбирается индивидуально. В том случае, если рекомендуемая доза не превышает 1 мг/сутки, всю дозу препарата можно принять за один раз (единовременно). В случае приема более высокой дозы рекомендуется её разделить на два приёма.\u003Cbr\u003EРекомендуемая начальная доза:\u003Cbr\u003EДети от 6 месяцев и старше: 0,25-0,5 мг в сутки. При необходимости доза может быть увеличена до 1 мг/сутки.\u003Cbr\u003EВзрослые/пожилые пациенты: 1-2 мг в сутки.\u003Cbr\u003EДоза при поддерживающем лечении:\u003Cbr\u003EДети от 6 месяцев и старше: 0,25-2 мг в сутки.\u003Cbr\u003EВзрослые: 0,5-4 мг в сутки. В случае тяжелых, обострений доза может быть увеличена.\u003Cbr\u003EДля всех пациентов желательно определить минимальную эффективную поддерживающую дозу.\u003Cbr\u003EВ случае необходимости достижения дополнительного терапевтического эффекта можно рекомендовать увеличение суточной дозы (до 1 мг/сутки) Пульмикорта вместо комбинации препарата с пероральными глюкокортикостероидами; благодаря более низкому риску развития системных эффектов. \u003Cbr\u003EПациенты, получающие пероральные глюкокортикостероиды \u003Cbr\u003EОтмену пероральных глюкокортикостероидов необходимо начинать на фоне стабильного состояния здоровья пациента. В течение 10 дней необходимо принимать высокую дозу Пульмикорта на фоне приема пероральных глюкокортикостероидов в привычной дозе. В дальнейшем в течение месяца следует постепенно снижать дозу пероральных глюкокортикостероидов (например, по 2,5 мг преднизолона или его аналога) до минимальной эффективной дозы. Во многих случаях удаётся полностью отказаться от приёма пероральных глюкокортикостероидов. Поскольку Пульмикорт, применяемый в виде суспензии с помощью небулайзера, попадает в легкие при вдохе важно проинструктировать пациента вдыхать препарат через мундштук небулайзера спокойно и ровно.\u003Cbr\u003EНет данных о применении будесонида у пациентов с почечной недостаточностью или нарушением функции печени. Принимая во внимание тот факт, что будесонид выводится путем биотрансформации в печени, можно ожидать увеличения длительности действия препарата у пациентов с выраженным циррозом печени.\u003Cbr\u003EСтенозирующий ларинготрахеит (ложный круп)\u003Cbr\u003EДети от 6 месяцев и старше: 2 мг в сутки.\u003Cbr\u003EДозу препарата можно принять за один раз (единовременно) или разделить ее на два приема по 1 мг с интервалом в 30 мин.\u003Cbr\u003EНарушение функции печени или почек\u003Cbr\u003EНет данных о применении будесонида у пациентов с нарушением функции печени или почек. Принимая во внимание тот факт, что будесонид выводится путем биотрансформации в печени, можно ожидать увеличения экспозиции препарата у пациентов с выраженным циррозом печени.\u003Cbr\u003E"},{"name":"Побочные действия","value":"До 10% пациентов, принимающих препарат, могут испытывать следующие побочные эффекты:\u003Cbr\u003EЧасто (\u003E1/100)\u003Cbr\u003EДыхательные пути: кандидоз ротоглотки, раздражение слизистой оболочки глотки, кашель, охриплость голоса, сухость во рту.\u003Cbr\u003EРедко (\u003C1/1000)\u003Cbr\u003EАллергические реакции: ангионевротический отек.\u003Cbr\u003EЦНС: головная боль.\u003Cbr\u003EДерматологические реакции: крапивница, сыпь, контактный дерматит.\u003Cbr\u003EДыхательные пути: бронхоспазм.\u003Cbr\u003EСо стороны ЦНС: возможны нервозность, возбудимость, депрессия, нарушения поведения.\u003Cbr\u003EВ отдельных случаях могут возникать симптомы, вызванные системным действием ГКС (включая гипофункцию надпочечников).\u003Cbr\u003EПрочие: редко - появление кровоподтеков на коже, раздражение кожи лица при использовании небулайзера с маской."},{"name":"Фармакологическое действие","value":"Будесонид, ингаляционный глюкокортикостероид, в рекомендованных дозах оказывает противовоспалительное действие в бронхах, снижая выраженность симптомов и частоту обострений бронхиальной астмы с меньшей частотой побочных эффектов, чем при использовании системных глюкокортикостероидов. Уменьшает выраженность отека слизистой бронхов, продукцию слизи, образование мокроты и гиперреактивность дыхательных путей. Хорошо переносится при длительном лечении, не обладает минералокортикостероидной активностью.\u003Cbr\u003EВремя начала терапевтического эффекта после ингаляции одной дозы препарата составляет несколько часов. Максимальный терапевтический эффект достигается через 1-2 недели после лечения. Будесонид оказывает профилактическое действие на течение бронхиальной астмы и не влияет на острые проявления заболевания.\u003Cbr\u003EПоказано дозозависимое воздействие на содержание кортизола в плазме и моче на фоне приёма Пульмикорта. В рекомендованных дозах препарат оказывает значительно меньшее влияние на надпочечную функцию, чем преднизолон в дозе 10 мг, как было показано в АКТГ тестах."},{"name":"Фармакологическая группа","value":"глюкокортикостероид для местного применения"},{"name":"Форма выпуска","value":"суспензия"},{"name":"Способ применения/введения","value":"ингалятивный"},{"name":"Минимальный возраст применения","value":"от 6 месяцев"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре ниже 30°С. Хранить в недоступном для детей месте. Препарат в контейнерах должен быть использован в течение 3 месяцев после вскрытия конверта. Открытый контейнер должен быть использован в течение 12 часов. Контейнеры следует хранить в конверте для защиты их от света."},{"name":"Передозировка","value":"При острой передозировке клинических проявлений не возникает. При длительном использовании препарата в дозах, значительно превышающих рекомендуемые, может развиться системный глюкокортикостероидный эффект в виде гиперкортицизма и подавления функции надпочечников."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность: наблюдение за беременными женщинами, принимавшими будесонид, не выявило аномалий развития у плода, тем не менее нельзя полностью исключить риск их развития, поэтому во время беременности в связи с возможностью ухудшения течения бронхиальной астмы следует использовать минимальную эффективную дозу будесонида.\u003Cbr\u003EЛактация: Будесонид проникает в грудное молоко, однако при применении Пульмикорта в терапевтических дозах воздействия на ребенка не отмечено. Пульмикорт может применяться во время грудного кормления."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Пульмикорт не оказывает влияния на способность управлять автомобилем или другими механизмами."},{"name":"Особые указания","value":"Для сведения к минимуму риска грибкового поражения ротоглотки следует проинструктировать пациента о необходимости тщательно полоскать рот водой после каждой ингаляции препарата.\u003Cbr\u003EСледует избегать совместного назначения будесонида с кетоконазолом, итраконазолом или другими потенциальными ингибиторами CYP3A4. В случае, если будесонид и кетоконазол или другие потенциальные ингибиторы CYP3A4 были назначены, следует увеличить время между приемом препаратов до максимально возможного.\u003Cbr\u003EИз-за возможного риска ослабления функции надпочечников особое внимание необходимо уделять пациентам, которые переводятся с пероральных глюкокортикостероидов на приём Пульмикорта. Также особое внимание следует уделять пациентам, принимавшим высокие дозы глюкокортикостероидов, или длительно получавшим максимально высокие рекомендованные дозы ингаляционных глюкокортикостероидов. В стрессовых ситуациях у таких пациентов могут проявиться признаки и симптомы надпочечниковой недостаточности. При стрессах или в случаях хирургического вмешательства рекомендуется проводить дополнительную терапию системными глюкокортикостероидами. Особое внимание необходимо уделять пациентам, которые переводятся с системных на ингаляционные глюкокортикостероиды (Пульмикорт) или в случае, когда можно ожидать нарушение гипофизарно-надпочечниковой функции. У таких пациентов следует с особой осторожностью снижать дозу системных глюкокортикостероидов и контролировать гипоталамо-гипофизарно-надпочечниковую функцию. Также пациентам может потребоваться добавление пероральных глюкокортикостероидов в период стрессовых ситуаций, таких как травма, хирургическое вмешательство и т.д.\u003Cbr\u003EПри переходе с пероральных глюкокортикостероидов на Пульмикорт пациенты могут почувствовать ранее наблюдавшиеся симптомы, такие как мышечные боли или боли в суставах. В таких случаях может понадобиться временное увеличение дозы пероральных глюкокортикостероидов. В редких случаях могут наблюдаться такие симптомы как чувство усталости, головная боль, тошнота и рвота, указывающие на системную недостаточность глюкокортикостероидов.\u003Cbr\u003EЗамена пероральных глюкокортикостероидов на ингаляционные иногда приводит к проявлению сопутствующей аллергии, например, ринита и экземы, которые ранее купировались системными препаратами.\u003Cbr\u003EУ детей и подростков, получающих лечение глюкокортикостероидами (независимо от способа доставки) в течение продолжительного периода, рекомендуется регулярно контролировать показатели роста. При назначении глюкокортикостероидов следует принимать во внимание соотношение пользы применения препарата и возможного риска замедления роста.\u003Cbr\u003EПрименение будесонида в дозе до 400 мкг в сутки у детей старше 3-х лет не приводило к возникновению системных эффектов. Биохимические признаки системного эффекта препарата могут встречаться при приёме препарата в дозе от 400 до 800 мкг в сутки. При превышении дозы 800 мкг в сутки системные эффекты препарата встречаются часто. Применение глюкокортикостероидов для лечения бронхиальной астмы может вызывать нарушение роста. Результаты наблюдений за детьми и подростками, получавшими будесонид в течение длительного периода (до 11 лет), показали, что рост пациентов достигает ожидаемых нормативных показателей для взрослых.\u003Cbr\u003EТерапия ингаляционным будесонид ом 1 или 2 раза в сутки показала эффективность для профилактики бронхиальной астмы физического усилия.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EТребуется более тщательное наблюдение за больными: у пациентов с грибковыми, вирусными, бактериальными инфекциями органов дыхания, циррозом печени; при назначений следует принимать во внимание возможное проявление системного действия глюкокортикостероидов."},{"name":"Взаимодействие","value":"Не наблюдалось взаимодействия будесонида с другими препаратами, используемыми при лечении бронхиальной астмы.\u003Cbr\u003EКетоконазол (200 мг один раз в сутки) повышает плазменную концентрацию перорального будесонида (3 мг один раз в сутки) в среднем в 6 раз при совместном приёме. При приеме кетоконазола через 12 часов после приёма будесонида концентрация последнего в плазме крови увеличивалась в среднем в 3 раза. Информация о подобном взаимодействии при приёме будесонида в виде ингаляции отсутствует, однако предполагается, что и в этом случае следует ожидать увеличение концентрации будесонида в плазме крови. В случае необходимости приема кетоконазола и будесонида следует увеличить время между приёмом препаратов до максимально возможного. Также следует рассмотреть возможность снижения дозы будесонида. Другой потенциальный ингибитор CYP3A4, например, итраконазол, также значительно повышает плазменную концентрацию будесонида. Предварительная ингаляция бета-адреностимуляторов расширяет бронхи, улучшает поступление будесонида в дыхательные пути и усиливает его терапевтический эффект. 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Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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1 039 ₽

  • Завтра, самовывоз • 0 ₽
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Ещё может подойти

  • Пульмикорт Турбухалер пор. д/инг. дозир., 200 мкг/доза, 100 шт.
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    Пульмикорт Турбухалер пор. д/инг. дозир., 200 мкг/доза, 100 шт.

    Рейтинг товара: 4.3 из 5
    на основе 8 оценок
    Цена 481 ₽
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  • Беродуал р-р д/инг., 0.25 мг+0.5 мг/мл, 20 мл, 1 шт.
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    Беродуал р-р д/инг., 0.25 мг+0.5 мг/мл, 20 мл, 1 шт.

    Рейтинг товара: 4.8 из 5
    на основе 43 оценки
    Цена 288 ₽
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  • Пульмибуд сусп. д/инг. дозир., 0.25 мг/мл, 2 мл, 20 шт.
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    Пульмибуд сусп. д/инг. дозир., 0.25 мг/мл, 2 мл, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 22 оценки
    Цена 667 ₽
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  • Беродуал н аэр. д/инг. дозир. доз, 20 мкг+50 мкг/доза, 10 мл, 1 шт.
    –10 %
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    Беродуал н аэр. д/инг. дозир. доз, 20 мкг+50 мкг/доза, 10 мл, 1 шт.

    Рейтинг товара: 4.9 из 5
    на основе 17 оценок
    Цена 593 ₽ вместо 658
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  • Симбикорт турбухалер пор. д/инг. дозир., 80 мкг+4.5 мкг/доза, 60 шт.
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    Симбикорт турбухалер пор. д/инг. дозир., 80 мкг+4.5 мкг/доза, 60 шт.

    Рейтинг товара: 4.8 из 5
    на основе 42 оценки
    Цена 1 114 ₽
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  • Симбикорт Рапихалер аэр. д/инг. дозир., 80 мкг+4.5 мкг/доза, 120 шт.
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    Симбикорт Рапихалер аэр. д/инг. дозир., 80 мкг+4.5 мкг/доза, 120 шт.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    Цена 2 299 ₽
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  • Пульмибуд сусп.д/инг.дозир., 0.5 мг/мл, 2 мл, 20 шт.
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    Пульмибуд сусп.д/инг.дозир., 0.5 мг/мл, 2 мл, 20 шт.

    Цена 901 ₽
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  • Сингуляр таб. жев., 4 мг, 14 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-a7ys09oj0nk/toggleWishlist":{"skuId":"186487584","productId":1436721413,"offerId":"6zKHzz8a_zQUa_QBbLZEvg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxsXen7GE6MosEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIhcKKrQUQoKb2WBiE3LAIIOHcwQc=","sign":"a5V/vsKAJZ3/pV78QyOcNK9pFR90ifPsoC3Z8gOLXYs="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-a7ys09oj0nk/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Сингуляр таб. жев., 4 мг, 14 шт.

    Рейтинг товара: 4.8 из 5
    на основе 19 оценок
    Цена 1 399 ₽
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  • Сингуляр таб. жев., 5 мг, 14 шт.
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    Сингуляр таб. жев., 5 мг, 14 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 1 369 ₽
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Инструкция

Показания к применению

- Бронхиальная астма, требующая поддерживающей терапии глюкокортикостероидами.
- Хроническая обструктивная болезнь легких (ХОБЛ)
Стенозирующий ларинготрахеит (ложный круп).

Противопоказания

- Повышенная чувствительность к будесониду.
- Детский возраст до 6 месяцев.

Способ применения и дозы

Доза препарата подбирается индивидуально. В том случае, если рекомендуемая доза не превышает 1 мг/сутки, всю дозу препарата можно принять за один раз (единовременно). В случае приема более высокой дозы рекомендуется её разделить на два приёма.
Рекомендуемая начальная доза:
Дети от 6 месяцев и старше: 0,25-0,5 мг в сутки. При необходимости доза может быть увеличена до 1 мг/сутки.
Взрослые/пожилые пациенты: 1-2 мг в сутки.
Доза при поддерживающем лечении:
Дети от 6 месяцев и старше: 0,25-2 мг в сутки.
Взрослые: 0,5-4 мг в сутки. В случае тяжелых, обострений доза может быть увеличена.
Для всех пациентов желательно определить минимальную эффективную поддерживающую дозу.
В случае необходимости достижения дополнительного терапевтического эффекта можно рекомендовать увеличение суточной дозы (до 1 мг/сутки) Пульмикорта вместо комбинации препарата с пероральными глюкокортикостероидами; благодаря более низкому риску развития системных эффектов.
Пациенты, получающие пероральные глюкокортикостероиды
Отмену пероральных глюкокортикостероидов необходимо начинать на фоне стабильного состояния здоровья пациента. В течение 10 дней необходимо принимать высокую дозу Пульмикорта на фоне приема пероральных глюкокортикостероидов в привычной дозе. В дальнейшем в течение месяца следует постепенно снижать дозу пероральных глюкокортикостероидов (например, по 2,5 мг преднизолона или его аналога) до минимальной эффективной дозы. Во многих случаях удаётся полностью отказаться от приёма пероральных глюкокортикостероидов. Поскольку Пульмикорт, применяемый в виде суспензии с помощью небулайзера, попадает в легкие при вдохе важно проинструктировать пациента вдыхать препарат через мундштук небулайзера спокойно и ровно.
Нет данных о применении будесонида у пациентов с почечной недостаточностью или нарушением функции печени. Принимая во внимание тот факт, что будесонид выводится путем биотрансформации в печени, можно ожидать увеличения длительности действия препарата у пациентов с выраженным циррозом печени.
Стенозирующий ларинготрахеит (ложный круп)
Дети от 6 месяцев и старше: 2 мг в сутки.
Дозу препарата можно принять за один раз (единовременно) или разделить ее на два приема по 1 мг с интервалом в 30 мин.
Нарушение функции печени или почек
Нет данных о применении будесонида у пациентов с нарушением функции печени или почек. Принимая во внимание тот факт, что будесонид выводится путем биотрансформации в печени, можно ожидать увеличения экспозиции препарата у пациентов с выраженным циррозом печени.
Полная инструкция
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Пульмикорт сусп. д/инг.
Пульмикорт сусп. д/инг., 0.5 мг/мл, 2 мл, 20 шт.
4.8
(62)
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17 вопросов
Инструкция

1 039 ₽

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4.8
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У продавца:62 оценки·14 отзывов
У всех продавцов:614 оценок·157 отзывов
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user avatar
Год назад • Владимир Ивонтьев • Куплен на Маркете
Достоинства: Замечательный препарат, убирает отдышку
Недостатки: Цена, очень уж дорого, для хронических больных
Комментарий: Имеет накопительный эффект, для полноценного действия необходимо применять не менее пяти дней
user avatar
2 недели назад • Светлана Куклачева • Куплен на Маркете
Достоинства: Быстрая помощь при стенозе
Недостатки: Нет
Комментарий: Я еще использую для промывания пазух при гайморите. Отек сходит быстро и вся слизь выходит.
user avatar
3 месяца назад • Игорь Гурко • Куплен на Маркете
Комментарий: Хорошее лекарство, после первого применения кашель стал гораздо меньше, а после 4го практически пропал
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