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Описание

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Верошпилактон таб., 25 мг, 20 шт.

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5.0
(5)
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Коротко о товаре

Артикул Маркета
3123129562
Тип препарата
Назначение
Действующее вещество
Возраст
от 3 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"9908146043242777415":{"specItems":[{"name":"Артикул Маркета","value":"3123129562","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"гиперальдостеронизм, гипокалиемия, гипомагниемия, отечный синдром, эссенциальная гипертензия","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["36476390:36618955,36618786,36618440,36618237,36617252"]}}},{"name":"действующее вещество","value":"Спиронолактон","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28710514"]}}},{"name":"возраст","value":"от 3 лет"},{"name":"форма выпуска","value":"таблетки"},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"9908146043242777415":{"specItems":[{"name":"Артикул Маркета","value":"3123129562","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Действующее вещество","value":"Спиронолактон","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28710514"]}}},{"name":"Возраст","value":"От 3 лет"},{"name":"Форма выпуска","value":"Таблетки"}]}},"fullSpecs":{"9908146043242777415":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"гиперальдостеронизм, гипокалиемия, гипомагниемия, отечный синдром, эссенциальная гипертензия","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["36476390:36618955,36618786,36618440,36618237,36617252"]}}},{"name":"Показания к применению","value":"Эссенциальная гипертензия (в составе комбинированной терапии). Отечный синдром при хронической сердечной недостаточности (может применяться в монотерапии и в комбинации со стандартной терапией). Состояния, при которых может обнаруживаться вторичный гиперальдостеронизм, включая цирроз печени, сопровождающийся асцитом и/или отеками, нефротический синдром, а также другие состояния, сопровождающиеся отеками. Гипокалиемия/гипомагниемия (в качестве вспомогательного средства для ее профилактики во время лечения диуретиками и при невозможности применения других способов коррекции содержания калия). Первичный гиперальдостеронизм (синдром Конна) - для короткого предоперационного курса лечения. Для установления диагноза первичного гиперальдостеронизма."},{"name":"Противопоказания","value":"Повышенная чувствительность к какому-либо из компонентов препарата, болезнь Аддисона, гиперкалиемия, гипонатриемия, тяжелая почечная недостаточность (клиренс креатинина менее 10 мл/мин), анурия, беременность, период кормления грудью. Детский возраст (до 3 лет), в связи с твердой лекарственной формой."},{"name":"Состав","value":"Действующее вещество: спиронолактон – 25 мг\u003Cbr\u003EВспомогательные вещества: магния стеарат, лактоза (сахар молочный), крахмал картофельный, кремния диоксид коллоидный (аэросил), тальк."},{"name":"Действующее вещество","value":"Спиронолактон","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28710514"]}}},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003E\nЭссенциалъная гипертензия\u003Cbr\u003E\nСуточная доза для взрослых обычно составляет 50-100 мг однократно и может быть увеличена до 200 мг, при этом увеличивать дозу следует постепенно, 1 раз в 2 недели. Чтобы добиться адекватного ответа на терапию, препарат необходимо принимать не менее 2 недель. При необходимости проводят корректировку дозы.\u003Cbr\u003E\nИдиопатический гиперальдостеронизм Назначают 100-400 мг/сут. \u003Cbr\u003E\nВыраженный гиперальдостеронизм и гипокалиемия\u003Cbr\u003E\nНазначают 300 мг/сут (максимально 400 мг/сут) за 2-3 приема, при улучшении состояния дозу постепенно снижают до 25 мг/сут. \u003Cbr\u003E\nГипокалиемия и/или гипомагниемия\u003Cbr\u003E\nПри гипокалиемии и/или гипомагниемии, вызванных терапией диуретиками, назначают препарат в дозе 25-100 мг/сут, однократно или в несколько приёмов. Максимальная суточная доза 400 мг, если препараты калия для приема внутрь или другие методы восполнения его дефицита неэффективны. \u003Cbr\u003E\nДиагностика и лечение первичного гиперальдостеронизма\u003Cbr\u003E\nВ качестве диагностического средства при коротком диагностическом тесте: в течение 4 дней по 400 мг/сут, распределив на несколько приемов в день. При увеличении содержания калия в крови во время приема препарата и снижении после отмены его можно предполагать наличие первичного гиперальдостеронизма. При длительном диагностическом тесте: в той же дозе в течение 3-4 недель. При достижении коррекции гипокалиемии и артериальной гипертензии можно предполагать наличие первичного гиперальдостеронизма. \u003Cbr\u003E\nКороткий курс предоперационной терапии первичного гиперальдостеронизма\u003Cbr\u003E\nПосле того как диагноз гиперальдостеронизма установлен с помощью более точных диагностических методов, препарат Верошпилактон следует принимать по 100-400 мг/сут, разделив на 1-4 приёма в сутки в течение всего периода подготовки к хирургическому вмешательству. Если хирургическое вмешательство не показано, то препарат Верошпилактон применяется для проведения длительной поддерживающей терапии, при этом применяется наименьшая эффективная доза, которая подбирается индивидуально для каждого пациента. \u003Cbr\u003E\nОтеки на фоне нефротического синдрома\u003Cbr\u003E\nСуточная доза для взрослых обычно составляет 100-200 мг/сут. Не выявлено влияния спиронолактона на основной патологический процесс, и потому применение данного препарата рекомендуется только в тех случаях, когда другие виды терапии оказываются неэффективны. \u003Cbr\u003E\nОтечный синдром на фоне хронической сердечной недостаточности\u003Cbr\u003E\nЕжедневно, в течение 5 дней по 100-200 мг/сут в 2-3 приема, в комбинации с \"петлевым\" или тиазидным диуретиком. В зависимости от эффекта, суточную дозу уменьшают до 25 мг. Поддерживающая доза подбирается индивидуально. Максимальная доза 200 мг/сут.\u003Cbr\u003E\nОтеки на фоне цирроза печени\u003Cbr\u003E\nЕсли в моче соотношение ионов натрия и калия (Na+/K+) превышают 1,0, то суточная доза для взрослых обычно составляет 100 мг. Если соотношение меньше 1,0, то суточная доза для взрослых обычно равна 200-400 мг. Поддерживающая доза подбирается индивидуально. \u003Cbr\u003E\nОтеки у детей\u003Cbr\u003E\nНачальная доза у детей старше 3 лет составляет 1-3,3 мг/кг массы тела или 30- 90 мг/м2/сут. в 1-4 приема. Через 5 дней дозу корректируют и при необходимости увеличивают в 3 раза по сравнению с первоначальной."},{"name":"Побочные действия","value":"Со стороны желудочно-кишечного тракта: тошнота, рвота, диарея, изъязвления и кровотечения из желудочно-кишечного тракта, гастрит, кишечная колика, боль в животе, запор.\u003Cbr\u003E\nСо стороны печени: нарушение функции печени. \u003Cbr\u003E\nСо стороны центральной нервной системы: атаксия, заторможенность, головокружение, головная боль, сонливость, летаргия, спутанность сознания, мышечный спазм. \u003Cbr\u003E\nСо стороны крови и лимфатической системы: агранулоцитоз, тромбоцитопения, мегалобластоз. \u003Cbr\u003E\nСо стороны лабораторных показателей: гиперурикемия, гиперкреатининемия, повышение концентрации мочевины, нарушение водно-электролитного баланса (гиперкалиемия, гипонатриемия) и кислотно-основного состояния (метаболический гиперхлоремический ацидоз или алкалоз). \u003Cbr\u003E\nСо стороны эндокринной системы: огрубение голоса, у мужчин - гинекомастия (вероятность развития зависит от дозы, длительности лечения и, обычно, носит обратимый характер, и после отмены препарата исчезает, и лишь в редких случаях грудная железа остается несколько увеличенной); снижение потенции и эрекции; у женщин - нарушение менструального цикла; дисменорея, аменорея, метроррагия в климактерическом периоде, гирсутизм, боли в области молочных желез, карцинома молочной железы (наличие связи с приемом препарата не установлено). \u003Cbr\u003E\nАллергические реакции: крапивница, макулопапулезная и эритематозная сыпь, лекарственная лихорадка, кожный зуд, эозинофилия, синдром Стивена-Джонсона, токсический эпидермальный некролиз. \u003Cbr\u003E\nСо стороны кожи и подкожных тканей: алопеция, гипертрихоз. \u003Cbr\u003E\nСо стороны почек и мочевыводящих путей: острая почечная недостаточность. \u003Cbr\u003E\nСо стороны скелетно-мышечной и соединительной ткани: судороги икроножных мышц, остеомаляция. \u003Cbr\u003E\nСо стороны дыхательной системы, органов грудной клетки и средостения: одышка. \u003Cbr\u003E\nЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили другие нежелательные явления не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Спиронолактон является калийсберегающим диуретиком, специфическим антагонистом альдостерона пролонгированного действия (минералокортикостероидный гормон коры надпочечников). В дистальных отделах нефрона спиронолактон препятствует задержке альдостероном натрия и воды и подавляет калийвыводягций эффект альдостерона, снижает синтез пермеаз в альдостерон-зависимом участке собирательных трубочек и дистальных канальцев. Связываясь с рецепторами альдостерона, увеличивает экскрецию ионов натрия, хлора и воды с мочой, уменьшает выведение ионов калия и мочевины, снижает кислотность мочи. Усиление диуреза обусловлено наличием диуретического эффекта, который непостоянен. Диуретический эффект проявляется на 2-5 день лечения."},{"name":"Фармакологическая группа","value":"диуретическое калийсберегающее средство"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 3 лет"},{"name":"Условия хранения","value":"В сухом, защищенном от света месте, при температуре не выше 25°С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: тошнота, рвота, головокружение, диарея, кожная сыпь, гиперкалиемия (парестезии, мышечная слабость, аритмии), гипонатриемия (сухость слизистой оболочки полости рта, жажда, сонливость) гиперкальциемия, дегидратация, увеличение концентрации мочевины.\u003Cbr\u003E\nЛечение: промывание желудка, симптоматическое лечение дегидратации. При гиперкалиемии необходимо нормализовать водно-электролитный баланс с помощью калийвыводящих диуретиков, быстрого парентерального введения 5-20 % раствора декстрозы (глюкоза) с инсулином из расчета 0,25-0,5 ЕД на 1 г декстрозы (глюкоза); при необходимости можно ввести повторно. В тяжелых случаях проводят гемодиализ."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Верошпилактон противопоказано при беременности и в период кормления грудью."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Необходимо соблюдать осторожность при управлении транспортными средствами и работе с механизмами, требующими повышенной концентрации внимания и быстроты реакций (риск развития головокружения и сонливости)."},{"name":"Особые указания","value":"Возможно временное повышение уровня азота мочевины в сыворотке крови, особенно при сниженной функции почек и гиперкалиемии. Возможен обратимый гиперхлоремический метаболический ацидоз.\u003Cbr\u003E\nПри болезнях почек и печени, а также в пожилом возрасте необходим регулярный контроль электролитов сыворотки крови и функции почек.\u003Cbr\u003E\nПрепарат затрудняет определение дигоксина, кортизола и адреналина в крови.\u003Cbr\u003E\nНесмотря на отсутствие прямого воздействия на углеводный обмен, наличие сахарного диабета, особенно с диабетической нефропатией, требует особой осторожности из-за возможности развития гиперкалиемии. \u003Cbr\u003E\nПри лечении нестероидными противовоспалительными препаратами следует контролировать функцию почек и уровень электролитов в крови.\u003Cbr\u003E\nСледует избегать пищи, богатой калием.\u003Cbr\u003E\nВо время лечения употребление алкоголя противопоказано.\u003Cbr\u003E\nС осторожностью применяется при следующих состояниях: гиперкальциемия, метаболический ацидоз, атриовентрикулярная блокада (гиперкалиемия способствует усилению ее), сахарный диабет (при подтвержденной или предполагаемой хронической почечной недостаточности), диабетическая нефропатия, хирургические вмешательства, прием лекарственных средств, вызывающих гинекомастию, местная и общая анестезия, пожилой возраст, нарушение менструального цикла, увеличение молочных желез, печеночная недостаточность."},{"name":"Взаимодействие","value":"Снижает эффект антикоагулянтов, непрямых антикоагулянтов (гепарина, производных кумарина, индандинона) и токсичность сердечных гликозидов (т. к. нормализация уровня калия в крови препятствует токсичности).\u003Cbr\u003E\nУсиливает метаболизм феназола (антипирина). Снижает чувствительность сосудов к ноэпинефрину (требует соблюдения осторожности при проведении анестезии), увеличивает период полувыведения дигоксина - возможна интоксикация - дигоксином.\u003Cbr\u003E\nУсиливает токсическое действие лития из-за снижения клиренса. Ускоряет метаболизм и выведение карбеноксолона.\u003Cbr\u003E\nКарбеноксолон способствует задержке натрия спиронолактоном. Глюкокортикостероидные препараты и диуретики (производные бензотиадиазина, фуросемид, этакриновая кислота) усиливают и ускоряют диуретический и натрийуретический эффекты. \u003Cbr\u003E\nУсиливает действие диуретических и гипотензивных лекарственных средств. Нестероидные противовоспалительные средства снижают диуретический и натрийуретический эффекты, увеличивается риск развития гиперкалиемии. Глюкокортикостероидные препараты усиливают диуретический и натрийуретический эффект при гипоальбуминемии и/или гипонатриемия. \u003Cbr\u003E\nВозрастает риск развития гиперкалиемии при приеме с препаратами калия, калиевыми добавками и калийсберегающими диуретиками, ингибиторами ангиОтензин- конвертирующего энзима (ацидоз), антагонистами ангиотензина П, блокаторами альдоетерона, индометацина, циклоспорина. \u003Cbr\u003E\nСалицилаты, индометацин снижают диуретический эффект. Хлорид аммония, колестирамин способствуют развитию гиперкалиемического метаболического ацидоза. \u003Cbr\u003E\nФлудрокортизон вызывает парадоксальное усиление канальцевой секции калия. Снижает эффект митотана. \u003Cbr\u003E\nУсиливает эффект трипторелина, бусерелина, гонадорелина."},{"name":"Регистрационный номер","value":"ЛП-№(000485)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"28.12.2021"},{"name":"Владелец регистрационного удостоверения","value":"Алиум","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:17728945"]}}},{"name":"Изготовитель","value":"Алиум"},{"name":"Фасовщик","value":"Алиум"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Верошпилактон","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:18017983"]}}},{"name":"Срок годности","value":"48 мес."}]}},"fullSpecsGrouped":{"9908146043242777415":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"гиперальдостеронизм, гипокалиемия, гипомагниемия, отечный синдром, эссенциальная гипертензия"},{"name":"Показания к применению","value":"Эссенциальная гипертензия (в составе комбинированной терапии). Отечный синдром при хронической сердечной недостаточности (может применяться в монотерапии и в комбинации со стандартной терапией). Состояния, при которых может обнаруживаться вторичный гиперальдостеронизм, включая цирроз печени, сопровождающийся асцитом и/или отеками, нефротический синдром, а также другие состояния, сопровождающиеся отеками. Гипокалиемия/гипомагниемия (в качестве вспомогательного средства для ее профилактики во время лечения диуретиками и при невозможности применения других способов коррекции содержания калия). Первичный гиперальдостеронизм (синдром Конна) - для короткого предоперационного курса лечения. Для установления диагноза первичного гиперальдостеронизма."},{"name":"Противопоказания","value":"Повышенная чувствительность к какому-либо из компонентов препарата, болезнь Аддисона, гиперкалиемия, гипонатриемия, тяжелая почечная недостаточность (клиренс креатинина менее 10 мл/мин), анурия, беременность, период кормления грудью. Детский возраст (до 3 лет), в связи с твердой лекарственной формой."},{"name":"Состав","value":"Действующее вещество: спиронолактон – 25 мг\u003Cbr\u003EВспомогательные вещества: магния стеарат, лактоза (сахар молочный), крахмал картофельный, кремния диоксид коллоидный (аэросил), тальк."},{"name":"Действующее вещество","value":"Спиронолактон"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003E\nЭссенциалъная гипертензия\u003Cbr\u003E\nСуточная доза для взрослых обычно составляет 50-100 мг однократно и может быть увеличена до 200 мг, при этом увеличивать дозу следует постепенно, 1 раз в 2 недели. Чтобы добиться адекватного ответа на терапию, препарат необходимо принимать не менее 2 недель. При необходимости проводят корректировку дозы.\u003Cbr\u003E\nИдиопатический гиперальдостеронизм Назначают 100-400 мг/сут. \u003Cbr\u003E\nВыраженный гиперальдостеронизм и гипокалиемия\u003Cbr\u003E\nНазначают 300 мг/сут (максимально 400 мг/сут) за 2-3 приема, при улучшении состояния дозу постепенно снижают до 25 мг/сут. \u003Cbr\u003E\nГипокалиемия и/или гипомагниемия\u003Cbr\u003E\nПри гипокалиемии и/или гипомагниемии, вызванных терапией диуретиками, назначают препарат в дозе 25-100 мг/сут, однократно или в несколько приёмов. Максимальная суточная доза 400 мг, если препараты калия для приема внутрь или другие методы восполнения его дефицита неэффективны. \u003Cbr\u003E\nДиагностика и лечение первичного гиперальдостеронизма\u003Cbr\u003E\nВ качестве диагностического средства при коротком диагностическом тесте: в течение 4 дней по 400 мг/сут, распределив на несколько приемов в день. При увеличении содержания калия в крови во время приема препарата и снижении после отмены его можно предполагать наличие первичного гиперальдостеронизма. При длительном диагностическом тесте: в той же дозе в течение 3-4 недель. При достижении коррекции гипокалиемии и артериальной гипертензии можно предполагать наличие первичного гиперальдостеронизма. \u003Cbr\u003E\nКороткий курс предоперационной терапии первичного гиперальдостеронизма\u003Cbr\u003E\nПосле того как диагноз гиперальдостеронизма установлен с помощью более точных диагностических методов, препарат Верошпилактон следует принимать по 100-400 мг/сут, разделив на 1-4 приёма в сутки в течение всего периода подготовки к хирургическому вмешательству. Если хирургическое вмешательство не показано, то препарат Верошпилактон применяется для проведения длительной поддерживающей терапии, при этом применяется наименьшая эффективная доза, которая подбирается индивидуально для каждого пациента. \u003Cbr\u003E\nОтеки на фоне нефротического синдрома\u003Cbr\u003E\nСуточная доза для взрослых обычно составляет 100-200 мг/сут. Не выявлено влияния спиронолактона на основной патологический процесс, и потому применение данного препарата рекомендуется только в тех случаях, когда другие виды терапии оказываются неэффективны. \u003Cbr\u003E\nОтечный синдром на фоне хронической сердечной недостаточности\u003Cbr\u003E\nЕжедневно, в течение 5 дней по 100-200 мг/сут в 2-3 приема, в комбинации с \"петлевым\" или тиазидным диуретиком. В зависимости от эффекта, суточную дозу уменьшают до 25 мг. Поддерживающая доза подбирается индивидуально. Максимальная доза 200 мг/сут.\u003Cbr\u003E\nОтеки на фоне цирроза печени\u003Cbr\u003E\nЕсли в моче соотношение ионов натрия и калия (Na+/K+) превышают 1,0, то суточная доза для взрослых обычно составляет 100 мг. Если соотношение меньше 1,0, то суточная доза для взрослых обычно равна 200-400 мг. Поддерживающая доза подбирается индивидуально. \u003Cbr\u003E\nОтеки у детей\u003Cbr\u003E\nНачальная доза у детей старше 3 лет составляет 1-3,3 мг/кг массы тела или 30- 90 мг/м2/сут. в 1-4 приема. Через 5 дней дозу корректируют и при необходимости увеличивают в 3 раза по сравнению с первоначальной."},{"name":"Побочные действия","value":"Со стороны желудочно-кишечного тракта: тошнота, рвота, диарея, изъязвления и кровотечения из желудочно-кишечного тракта, гастрит, кишечная колика, боль в животе, запор.\u003Cbr\u003E\nСо стороны печени: нарушение функции печени. \u003Cbr\u003E\nСо стороны центральной нервной системы: атаксия, заторможенность, головокружение, головная боль, сонливость, летаргия, спутанность сознания, мышечный спазм. \u003Cbr\u003E\nСо стороны крови и лимфатической системы: агранулоцитоз, тромбоцитопения, мегалобластоз. \u003Cbr\u003E\nСо стороны лабораторных показателей: гиперурикемия, гиперкреатининемия, повышение концентрации мочевины, нарушение водно-электролитного баланса (гиперкалиемия, гипонатриемия) и кислотно-основного состояния (метаболический гиперхлоремический ацидоз или алкалоз). \u003Cbr\u003E\nСо стороны эндокринной системы: огрубение голоса, у мужчин - гинекомастия (вероятность развития зависит от дозы, длительности лечения и, обычно, носит обратимый характер, и после отмены препарата исчезает, и лишь в редких случаях грудная железа остается несколько увеличенной); снижение потенции и эрекции; у женщин - нарушение менструального цикла; дисменорея, аменорея, метроррагия в климактерическом периоде, гирсутизм, боли в области молочных желез, карцинома молочной железы (наличие связи с приемом препарата не установлено). \u003Cbr\u003E\nАллергические реакции: крапивница, макулопапулезная и эритематозная сыпь, лекарственная лихорадка, кожный зуд, эозинофилия, синдром Стивена-Джонсона, токсический эпидермальный некролиз. \u003Cbr\u003E\nСо стороны кожи и подкожных тканей: алопеция, гипертрихоз. \u003Cbr\u003E\nСо стороны почек и мочевыводящих путей: острая почечная недостаточность. \u003Cbr\u003E\nСо стороны скелетно-мышечной и соединительной ткани: судороги икроножных мышц, остеомаляция. \u003Cbr\u003E\nСо стороны дыхательной системы, органов грудной клетки и средостения: одышка. \u003Cbr\u003E\nЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили другие нежелательные явления не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Спиронолактон является калийсберегающим диуретиком, специфическим антагонистом альдостерона пролонгированного действия (минералокортикостероидный гормон коры надпочечников). В дистальных отделах нефрона спиронолактон препятствует задержке альдостероном натрия и воды и подавляет калийвыводягций эффект альдостерона, снижает синтез пермеаз в альдостерон-зависимом участке собирательных трубочек и дистальных канальцев. Связываясь с рецепторами альдостерона, увеличивает экскрецию ионов натрия, хлора и воды с мочой, уменьшает выведение ионов калия и мочевины, снижает кислотность мочи. Усиление диуреза обусловлено наличием диуретического эффекта, который непостоянен. Диуретический эффект проявляется на 2-5 день лечения."},{"name":"Фармакологическая группа","value":"диуретическое калийсберегающее средство"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 3 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В сухом, защищенном от света месте, при температуре не выше 25°С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: тошнота, рвота, головокружение, диарея, кожная сыпь, гиперкалиемия (парестезии, мышечная слабость, аритмии), гипонатриемия (сухость слизистой оболочки полости рта, жажда, сонливость) гиперкальциемия, дегидратация, увеличение концентрации мочевины.\u003Cbr\u003E\nЛечение: промывание желудка, симптоматическое лечение дегидратации. При гиперкалиемии необходимо нормализовать водно-электролитный баланс с помощью калийвыводящих диуретиков, быстрого парентерального введения 5-20 % раствора декстрозы (глюкоза) с инсулином из расчета 0,25-0,5 ЕД на 1 г декстрозы (глюкоза); при необходимости можно ввести повторно. В тяжелых случаях проводят гемодиализ."},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Верошпилактон противопоказано при беременности и в период кормления грудью."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Необходимо соблюдать осторожность при управлении транспортными средствами и работе с механизмами, требующими повышенной концентрации внимания и быстроты реакций (риск развития головокружения и сонливости)."},{"name":"Особые указания","value":"Возможно временное повышение уровня азота мочевины в сыворотке крови, особенно при сниженной функции почек и гиперкалиемии. Возможен обратимый гиперхлоремический метаболический ацидоз.\u003Cbr\u003E\nПри болезнях почек и печени, а также в пожилом возрасте необходим регулярный контроль электролитов сыворотки крови и функции почек.\u003Cbr\u003E\nПрепарат затрудняет определение дигоксина, кортизола и адреналина в крови.\u003Cbr\u003E\nНесмотря на отсутствие прямого воздействия на углеводный обмен, наличие сахарного диабета, особенно с диабетической нефропатией, требует особой осторожности из-за возможности развития гиперкалиемии. \u003Cbr\u003E\nПри лечении нестероидными противовоспалительными препаратами следует контролировать функцию почек и уровень электролитов в крови.\u003Cbr\u003E\nСледует избегать пищи, богатой калием.\u003Cbr\u003E\nВо время лечения употребление алкоголя противопоказано.\u003Cbr\u003E\nС осторожностью применяется при следующих состояниях: гиперкальциемия, метаболический ацидоз, атриовентрикулярная блокада (гиперкалиемия способствует усилению ее), сахарный диабет (при подтвержденной или предполагаемой хронической почечной недостаточности), диабетическая нефропатия, хирургические вмешательства, прием лекарственных средств, вызывающих гинекомастию, местная и общая анестезия, пожилой возраст, нарушение менструального цикла, увеличение молочных желез, печеночная недостаточность."},{"name":"Взаимодействие","value":"Снижает эффект антикоагулянтов, непрямых антикоагулянтов (гепарина, производных кумарина, индандинона) и токсичность сердечных гликозидов (т. к. нормализация уровня калия в крови препятствует токсичности).\u003Cbr\u003E\nУсиливает метаболизм феназола (антипирина). Снижает чувствительность сосудов к ноэпинефрину (требует соблюдения осторожности при проведении анестезии), увеличивает период полувыведения дигоксина - возможна интоксикация - дигоксином.\u003Cbr\u003E\nУсиливает токсическое действие лития из-за снижения клиренса. Ускоряет метаболизм и выведение карбеноксолона.\u003Cbr\u003E\nКарбеноксолон способствует задержке натрия спиронолактоном. Глюкокортикостероидные препараты и диуретики (производные бензотиадиазина, фуросемид, этакриновая кислота) усиливают и ускоряют диуретический и натрийуретический эффекты. \u003Cbr\u003E\nУсиливает действие диуретических и гипотензивных лекарственных средств. Нестероидные противовоспалительные средства снижают диуретический и натрийуретический эффекты, увеличивается риск развития гиперкалиемии. Глюкокортикостероидные препараты усиливают диуретический и натрийуретический эффект при гипоальбуминемии и/или гипонатриемия. \u003Cbr\u003E\nВозрастает риск развития гиперкалиемии при приеме с препаратами калия, калиевыми добавками и калийсберегающими диуретиками, ингибиторами ангиОтензин- конвертирующего энзима (ацидоз), антагонистами ангиотензина П, блокаторами альдоетерона, индометацина, циклоспорина. \u003Cbr\u003E\nСалицилаты, индометацин снижают диуретический эффект. Хлорид аммония, колестирамин способствуют развитию гиперкалиемического метаболического ацидоза. \u003Cbr\u003E\nФлудрокортизон вызывает парадоксальное усиление канальцевой секции калия. Снижает эффект митотана. \u003Cbr\u003E\nУсиливает эффект трипторелина, бусерелина, гонадорелина."},{"name":"Регистрационный номер","value":"ЛП-№(000485)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"28.12.2021"},{"name":"Владелец регистрационного удостоверения","value":"Алиум"},{"name":"Изготовитель","value":"Алиум"},{"name":"Фасовщик","value":"Алиум"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Верошпилактон"},{"name":"Срок годности","value":"48 мес."}]}],"transitionId":"tr_13618024241626787688"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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96 ₽

  • Сегодня, самовывоз • 0 ₽
ЕАПТЕКА
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{"widgets":{"@yandex-market/LazyLoader-market":{"/content/page/fancyPage/heroBannerCarousel/heroBannerCarousel/LazyLoader":{"widgetName":"@marketfront/HeroBannerCarousel","widgetId":"HeroBannerCarousel","options":{"resources":{"garsons":[{"id":"MadvCreatives","params":{"data":{"creatives":[{"mark":"hero","block":"ModelCardBannerList","blockParams":[{}]}]}}}]},"props":{"fixedRatio":true,"roundedCorners":true,"bannerFormat":"heroTouchOld"},"isChefRemixExp":false},"infinite":false,"cspNonce":"nSI9UzSieiOSb5elP28nRQ==","renderStrategy":"append"}}},"meta":{"/content/page/fancyPage/heroBannerCarousel/heroBannerCarousel/LazyLoader":{"name":"@yandex-market/LazyLoader-market"}}}
{"widgets":{"@marketfront/VisibilityLoaderMarket":{"/content/page/fancyPage/heroBannerCarousel/heroBannerCarousel":{"pageId":"market:offer","offset":3000,"epicModeForLazyLoad":"default","widgetId":"HeroBannerCarousel","__zoneName":""}}},"meta":{"/content/page/fancyPage/heroBannerCarousel/heroBannerCarousel":{"name":"@marketfront/VisibilityLoaderMarket"}}}
{"widgets":{"@market/CartService":{}},"meta":{"/content/page/fancyPage/cartService":{"name":"@market/CartService"}},"collections":{"sku":{},"product":{},"shop":{},"initialCartItem":{},"promo":{}}}

Ещё может подойти

  • Верошпирон таб., 25 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-395n8dvymm1/toggleWishlist":{"skuId":"101811674794","productId":1768328956,"offerId":"5cm0ydImvl_vaJ9I_4GyKw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQgZmv+tyBtto3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI/J2aywYQqr3Lo/sCGP7Vtggg19zBBw==","sign":"D0iduypH/AhtRkYJr8WF+VHdRFC5uVylLHJQb5qmHeo="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-395n8dvymm1/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Верошпирон таб., 25 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 23 оценки
    Цена 117 ₽
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  • Верошпилактон капс., 25 мг, 20 шт.
    –34 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wkakg6iyjvi/toggleWishlist":{"skuId":"101480514410","productId":1464010508,"offerId":"Gz0Tu7MZQGU-QV_gBtdy_Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQgZmv+tyBtto3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIjI6MugUQ6obXhfoCGLGLuggg19zBBw==","sign":"dh2/PNIr7xJ1BTkTRtR7IfTIvxpbIpo7opd36XWrg9M="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-wkakg6iyjvi/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Верошпилактон капс., 25 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 95 ₽ вместо 145
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  • Верошпилактон капс., 50 мг, 30 шт.
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    Верошпилактон капс., 50 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 232 ₽
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  • Верошпирон капс., 50 мг, 30 шт.
    –12 %
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    Верошпирон капс., 50 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 17 оценок
    Цена 230 ₽ вместо 260
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  • Спиронолактон таб., 25 мг, 20 шт.
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    Спиронолактон таб., 25 мг, 20 шт.

    Рейтинг товара: 4.6 из 5
    на основе 11 оценок
    Цена 79 ₽
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  • Верошпирон капс., 50 мг, 30 шт.
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    Верошпирон капс., 50 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 29 оценок
    Цена 217 ₽
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  • Аторвастатин таб. п/о плен., 40 мг, 30 шт.
    –16 %
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    Аторвастатин таб. п/о плен., 40 мг, 30 шт.

    Рейтинг товара: 4.3 из 5
    на основе 7 оценок
    Цена 379 ₽ вместо 449
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  • Лориста таб. п/о плен., 25 мг, 30 шт.
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    Лориста таб. п/о плен., 25 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 34 оценки
    Цена 119 ₽
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  • Бисопролол таб. п/о плен., 5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vqk3wuf8xoq/toggleWishlist":{"skuId":"228004076","productId":1401075592,"offerId":"9kyVvI7gZcH-bFX9LEdtxA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQgZmv+tyBtto3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIiO+KnAUQ7KHcbBi01YcEINfcwQc=","sign":"5ptT1HW7eXkFIY4lJ6H84ypRUCfBtYiNN5gLnEFw68U="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vqk3wuf8xoq/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Бисопролол таб. п/о плен., 5 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 35 оценок
    Цена 105 ₽
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  • Торасемид-СЗ таб., 10 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-m3zwdn3js5p/toggleWishlist":{"skuId":"186618052","productId":1401075464,"offerId":"oJ_ESfD79VusopA5_xvN0A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQgZmv+tyBtto3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIiO6KnAUQxKH+WBiu3tAHINfcwQc=","sign":"CMzBLQJEWQEZhv1MUPU4e5GXsNg+W5oGE2HfZmvUFuw="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-m3zwdn3js5p/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Торасемид-СЗ таб., 10 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 11 оценок
    Цена 326 ₽
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  • Периндоприл-Алиум таб., 4 мг, 30 шт., 1
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    Периндоприл-Алиум таб., 4 мг, 30 шт., 1

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 214 ₽
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Инструкция

Показания к применению

Эссенциальная гипертензия (в составе комбинированной терапии). Отечный синдром при хронической сердечной недостаточности (может применяться в монотерапии и в комбинации со стандартной терапией). Состояния, при которых может обнаруживаться вторичный гиперальдостеронизм, включая цирроз печени, сопровождающийся асцитом и/или отеками, нефротический синдром, а также другие состояния, сопровождающиеся отеками. Гипокалиемия/гипомагниемия (в качестве вспомогательного средства для ее профилактики во время лечения диуретиками и при невозможности применения других способов коррекции содержания калия). Первичный гиперальдостеронизм (синдром Конна) - для короткого предоперационного курса лечения. Для установления диагноза первичного гиперальдостеронизма.

Противопоказания

Повышенная чувствительность к какому-либо из компонентов препарата, болезнь Аддисона, гиперкалиемия, гипонатриемия, тяжелая почечная недостаточность (клиренс креатинина менее 10 мл/мин), анурия, беременность, период кормления грудью. Детский возраст (до 3 лет), в связи с твердой лекарственной формой.

Способ применения и дозы

Внутрь.
Эссенциалъная гипертензия
Суточная доза для взрослых обычно составляет 50-100 мг однократно и может быть увеличена до 200 мг, при этом увеличивать дозу следует постепенно, 1 раз в 2 недели. Чтобы добиться адекватного ответа на терапию, препарат необходимо принимать не менее 2 недель. При необходимости проводят корректировку дозы.
Идиопатический гиперальдостеронизм Назначают 100-400 мг/сут.
Выраженный гиперальдостеронизм и гипокалиемия
Назначают 300 мг/сут (максимально 400 мг/сут) за 2-3 приема, при улучшении состояния дозу постепенно снижают до 25 мг/сут.
Гипокалиемия и/или гипомагниемия
При гипокалиемии и/или гипомагниемии, вызванных терапией диуретиками, назначают препарат в дозе 25-100 мг/сут, однократно или в несколько приёмов. Максимальная суточная доза 400 мг, если препараты калия для приема внутрь или другие методы восполнения его дефицита неэффективны.
Диагностика и лечение первичного гиперальдостеронизма
В качестве диагностического средства при коротком диагностическом тесте: в течение 4 дней по 400 мг/сут, распределив на несколько приемов в день. При увеличении содержания калия в крови во время приема препарата и снижении после отмены его можно предполагать наличие первичного гиперальдостеронизма. При длительном диагностическом тесте: в той же дозе в течение 3-4 недель. При достижении коррекции гипокалиемии и артериальной гипертензии можно предполагать наличие первичного гиперальдостеронизма.
Короткий курс предоперационной терапии первичного гиперальдостеронизма
После того как диагноз гиперальдостеронизма установлен с помощью более точных диагностических методов, препарат Верошпилактон следует принимать по 100-400 мг/сут, разделив на 1-4 приёма в сутки в течение всего периода подготовки к хирургическому вмешательству. Если хирургическое вмешательство не показано, то препарат Верошпилактон применяется для проведения длительной поддерживающей терапии, при этом применяется наименьшая эффективная доза, которая подбирается индивидуально для каждого пациента.
Отеки на фоне нефротического синдрома
Суточная доза для взрослых обычно составляет 100-200 мг/сут. Не выявлено влияния спиронолактона на основной патологический процесс, и потому применение данного препарата рекомендуется только в тех случаях, когда другие виды терапии оказываются неэффективны.
Отечный синдром на фоне хронической сердечной недостаточности
Ежедневно, в течение 5 дней по 100-200 мг/сут в 2-3 приема, в комбинации с "петлевым" или тиазидным диуретиком. В зависимости от эффекта, суточную дозу уменьшают до 25 мг. Поддерживающая доза подбирается индивидуально. Максимальная доза 200 мг/сут.
Отеки на фоне цирроза печени
Если в моче соотношение ионов натрия и калия (Na+/K+) превышают 1,0, то суточная доза для взрослых обычно составляет 100 мг. Если соотношение меньше 1,0, то суточная доза для взрослых обычно равна 200-400 мг. Поддерживающая доза подбирается индивидуально.
Отеки у детей
Начальная доза у детей старше 3 лет составляет 1-3,3 мг/кг массы тела или 30- 90 мг/м2/сут. в 1-4 приема. Через 5 дней дозу корректируют и при необходимости увеличивают в 3 раза по сравнению с первоначальной.
Полная инструкция
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Верошпилактон таб.
Верошпилактон таб., 25 мг, 20 шт.
5.0
(5)
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Инструкция

96 ₽

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5.0
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У продавца:5 оценок·2 отзыва
У всех продавцов:15 оценок·4 отзыва
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3 месяца назад • Окси • Куплен на Маркете
Комментарий: старый проверенный препарат.
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5 месяцев назад • Наталья Рассказова • Куплен на Маркете
Достоинства: 👍
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