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Описание

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Урсофальк таб. п/о плен., 500 мг, 50 шт.

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4.8
(26)
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Коротко о товаре

Артикул Маркета
3351628927
Тип препарата
Назначение
Действующее вещество
Возраст
от 3 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"7943804868871560272":{"specItems":[{"name":"Артикул Маркета","value":"3351628927","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"билиарный рефлюкс-гастрит, билиарный цирроз печени, дискинезия желчевыводящих путей, муковисцидоз, растворение мелких и средних холестериновых камней при функционирующем желчном пузыре, холангит, хронические гепатиты","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["36476390:36618493,36618448,36618229,36617916,36617898,36617890,36617299"]}}},{"name":"действующее вещество","value":"Урсодезоксихолевая кислота","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28710121"]}}},{"name":"возраст","value":"от 3 лет"},{"name":"форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"страна-производитель","value":"Германия"}]}},"compactSpecs":{"7943804868871560272":{"specItems":[{"name":"Артикул Маркета","value":"3351628927","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Действующее вещество","value":"Урсодезоксихолевая кислота","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28710121"]}}},{"name":"Возраст","value":"От 3 лет"},{"name":"Форма выпуска","value":"Таблетки, покрытые пленочной оболочкой"}]}},"fullSpecs":{"7943804868871560272":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"печень, пищеварительная система","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34045610:34516029,34516020"]}}},{"name":"Назначение","value":"билиарный рефлюкс-гастрит, билиарный цирроз печени, дискинезия желчевыводящих путей, муковисцидоз, растворение мелких и средних холестериновых камней при функционирующем желчном пузыре, холангит, хронические гепатиты","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["36476390:36618493,36618448,36618229,36617916,36617898,36617890,36617299"]}}},{"name":"Показания к применению","value":"Растворение холестериновых камней желчного пузыря размером не более 15 мм в диаметре при нормальной сократительной способности желчного пузыря.\u003Cbr\u003E\nВ составе комплексной терапии:\u003Cbr\u003E\nПервичный билиарный цирроз при отсутствии признаков декомпенсации;\u003Cbr\u003E\nЛечение билиарного рефлюкс-гастрита;\u003Cbr\u003E\nПервичный склерозирующий холангит;\u003Cbr\u003E\nНеалкогольный стеатогепатит;\u003Cbr\u003E\nМуковисцидоз (в составе комплексной терапии) у взрослых и детей в возрасте старше 6 лет."},{"name":"Противопоказания","value":"Гиперчувствительность к урсодезоксихолевой кислоте или другим желчным кислотам, а также к вспомогательным веществам препарата;\u003Cbr\u003E\nРентгеноконтрастные (кальцифицированные) камни в желчном пузыре; нарушение сократимости желчного пузыря;\u003Cbr\u003E\nОстрое воспаление желчного пузыря и желчевыводящих путей;\u003Cbr\u003E\nОкклюзия желчных путей (закупорка общего желчного протока или пузырного протока),\u003Cbr\u003E\nЧастые эпизоды желчной колики\u003Cbr\u003E\nДетский возраст до 3 лет (для данной лекарственной формы);\u003Cbr\u003E\nЦирроз печени в стадии декоменсации;\u003Cbr\u003E\nТяжелая печеночная и/или почечная недостаточность.\u003Cbr\u003E\nПедиатрическая популяция\u003Cbr\u003E\nНеудачная портоэнтеростомия или без восстановления нормального оттока желчи у детей с атрезией желчевыводящих путей."},{"name":"Состав","value":"В одной таблетке, покрытой пленочной оболочкой, содержится:\u003Cbr\u003E\nАктивное вещество: Урсодезоксихолевая кислота - 500 мг\u003Cbr\u003E\nВспомогательные вещества: целлюлоза микрокристаллическая, повидон К25, кросповидон (тип А), тальк, магния стеарат, кремния диоксид коллоидный, полисорбат.\u003Cbr\u003E\nПленочная оболочка: гипромеллоза, тальк, макрогол 6000."},{"name":"Действующее вещество","value":"Урсодезоксихолевая кислота","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28710121"]}}},{"name":"Способ применения и дозы","value":"Для пациентов, которые не могут проглотить препарат Урсофальк таблетки, покрытые пленочной оболочкой 500 мг, или с массой тела менее 47 кг рекомендуется применять препарат Урсофальк в капсулах или суспензии. Таблетки, покрытые пленочной оболочкой, следует проглатывать целиком, запивая жидкостью. Их следует принимать регулярно.\u003Cbr\u003E\nДетям до трех лет и пациентам с затруднением проглатывания рекомендуется принимать Урсофальк в форме суспензии.\u003Cbr\u003E\nРастворение холестериновых желчных камней\u003Cbr\u003E\nРекомендуемая доза составляет 10 мг урсодезоксихолевой кислоты на 1 кг массы тела в сутки.\u003Cbr\u003E\nДля растворения желчных камней обычно требуется 6-24 месяцев. Если после 12 месяцев лечения размер камней не уменьшается, то лечение следует прекратить.\u003Cbr\u003E\nЭффективность лечения следует оценивать каждые 6 месяцев при ультразвуковом исследовании или рентгенографии. В ходе промежуточного обследования следует оценить, не произошло ли обызвествление камней за истекший период. В случае обызвествления камней, лечение следует прекратить.\u003Cbr\u003E\nВ составе комплексной терапии:\u003Cbr\u003E\nЛечение первичного билиарного цирроза\u003Cbr\u003E\nСуточная доза зависит от массы тела и варьирует от 11/2 до 31/2 таблеток (14 ± 2 мг урсодезоксихолевой кислоты на 1 кг массы тела).\u003Cbr\u003E\nВ течение первых 3 месяцев лечения, суточную дозу следует разделить на несколько приемов. После улучшения функциональных показателей печени, можно перейти на однократный прием суточной дозы в вечернее время.\u003Cbr\u003E\nПрименение препарата Урсофалька для лечения первичного билиарного цирроза может продолжаться в течение неограниченного времени.\u003Cbr\u003E\nУ пациентов с первичным билиарным циррозом в редких случаях клинические симптомы могут ухудшиться в начале лечения, например, может участиться зуд. В этом случае лечение следует продолжить, принимая по /г таблетке ежедневно, далее следует постепенно повышать дозу (увеличивая суточную дозу еженедельно на ½ таблетки) до тех пор, пока вновь не будет достигнут рекомендованный режим дозирования.\u003Cbr\u003E\nЛечение билиарного рефлюкс-гастрита\u003Cbr\u003E\nПо 250 мг (1/2 таблетки) ежедневно вечером перед сном.\u003Cbr\u003E\nКурс лечения от 10-14 дней до 6 месяцев, при необходимости - до 2 лет.\u003Cbr\u003E\nПервичный склерозирующий холангит - суточная доза 12-15 мг/кг в 2-3 приема. Также было показано, что при дозе 20 мг/кг в сутки улучшается гистология и функциональные тесты печени у пациентов с ПСХ.\u003Cbr\u003E\nНеалкоголъный стеатогепатит - средняя суточная доза 10-15 мг/кг в 2-3 приема. Длительность терапии составляет от 6-12 месяцев и более.\u003Cbr\u003E\nМуковисцидоз (в составе комплексной терапии) у взрослых и детей в возрасте старше 6 лет: 20 мг/кг/сут в 2-3 приема с последующим увеличением до 30 мг/кг/сут при необходимости."},{"name":"Побочные действия","value":"Оценка нежелательных явлений основана на следующей классификации:\u003Cbr\u003E\nОчень частые (≥1/10)\u003Cbr\u003E\nЧастые (≥1/100 - \u003C1/10)\u003Cbr\u003E\nНечастые (≥1/1000 - \u003C1/100)\u003Cbr\u003E\nРедкие (≥1/10000-\u003C1/1000)\u003Cbr\u003E\nОчень редкие (\u003C1/10000).\u003Cbr\u003E\nНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003E\nВ клинических исследованиях на фоне лечения урсодезоксихолевой кислотой часто наблюдались неоформленный стул или диарея.\u003Cbr\u003E\nНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003E\nВ очень редких случаях на фоне лечения урсодезоксихолевой кислотой может произойти кальцинирование желчных камней.\u003Cbr\u003E\nПри лечении развитых стадий первичного билиарного цирроза, в очень редких случаях наблюдалась декомпенсация цирроза печени, которая регрессирует после отмены препарата.\u003Cbr\u003E\nНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003E\nВ очень редких случаях могут наблюдаться аллергические реакции, в том числе крапивница.\u003Cbr\u003E\nЕсли любое из указанных нежелательных явлений усугубляется, или Вы заметили другие неуказанные нежелательные явления, пожалуйста, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Небольшое количество УДХК содержится в желчи.\nПосле приема внутрь УДХК снижает насыщение холестерина желчи, ингибируя абсорбцию холестерина в кишечнике и снижая его секрецию в желчь. Предположительно в результате диспергирования холестерина и образования жидких кристаллов происходит постепенное растворение холестериновых камней в желчном пузыре.\nСогласно современным представлениям считается, что действие УДХК при заболеваниях печени и холестатических заболеваниях связано с относительным обменом липофильных, подобных детергентам, токсичных желчных кислот на гидрофильные, цитопротекторные, нетоксичные УДХК, что приводит к улучшению секреторной функции гепатоцитов и к иммунорегуляторным процессам.\nПедиатрическая популяция\nМуковисцидоз (кистозный фиброз)\nСогласно данным клинических отчетов, имеется многолетний опыт (до 10 лет и более) лечения урсодезоксихолевой кислотой педиатрических больных, страдающих гепатобилиарной болезнью, связанной с муковисцидозом (CFAHD). Имеются данные о том, что терапия урсодезоксихолевой кислотой способна снижать пролиферацию желчных протоков, замедлять развитие повреждений, выявляемых при гистологическом исследовании, и даже способствовать обратному развитию изменений гепатобилиарной системы в случае, если терапия начинается на ранних стадиях CFAHD. В целях оптимизации эффективности лечения терапию урсодезоксихолевой кислотой следует начинать как можно раньше после установления диагноза CFAHD."},{"name":"Фармакологическая группа","value":"гепатопротекторы"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 3 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25°С. Хранить в недоступном для детей месте.\u003Cbr\u003E"},{"name":"Передозировка","value":"В случае передозировки возможна диарея. В целом, другие симптомы передозировки маловероятны, поскольку с увеличением дозы урсодезоксихолевой кислоты ее абсорбция снижается, а выведение с каловыми массами увеличивается.\u003Cbr\u003E\nСпецифическое лечение не требуется, последствия диареи лечатся симптоматически с восстановлением водно-электролитного баланса."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003E\nДанные об использовании урсодезоксихолевой кислоты у беременных женщин носят ограниченный характер или отсутствуют. Исследования на животных показали наличие репродуктивной токсичности на ранней стадии беременности. Во время беременности Урсофальк не должен применяться во время беременности, за исключением случаев, когда это явно необходимо.\u003Cbr\u003E\nГрудное вскармливание\u003Cbr\u003E\nСогласно данным нескольких документально подтвержденных случаев, уровень урсодезоксихолевой кислоты в грудном молоке у женщин очень низок и поэтому возникновение нежелательных реакций у детей при грудном вскармливании не ожидается."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"УДХК не оказывает влияния на способность управлять транспортными средствами и механизмами или же это влияние минимальное."},{"name":"Особые указания","value":"Прием препарата Урсофальк должен осуществляться под наблюдением врача. В течение первых 3 месяцев лечения следует контролировать функциональные показатели печени ACT, АЛТ и гамма-глутамилтранспептидазу каждые 4 недели, а затем каждые 3 месяца. Такой мониторинг позволит на раннем этапе выявить потенциальное ухудшение состояния печени, особенно у пациентов с поздней стадией ПБЦ. Кроме того, так можно быстро определить, реагирует ли пациент с первичным билиарным циррозом на проводимое лечение.\u003Cbr\u003E\nПри применении у пациентов для растворения холестериновых желчных камней:\u003Cbr\u003E\nДля того, чтобы оценить прогресс в лечении и для своевременного выявления признаков кальциноза камней в зависимости от размера камней, желчный пузырь следует визуализировать (пероральная холецистография) с осмотром затемнений в положении «стоя» и «лежа на спине» (ультразвуковое исследование) через 6-10 месяцев после начала лечения.\u003Cbr\u003E\nЕсли желчный пузырь невозможно визуализировать на рентгеновских снимках или в случаях кальциноза камней, слабой сократимости желчного пузыря или частых приступов колик, препарат Урсофальк применять не следует.\u003Cbr\u003E\nПри лечении пациентов на поздних стадиях первичного билиарного цирроза: Крайне редко отмечались случаи декомпенсации цирроза печени после прекращения терапии.\u003Cbr\u003E\nУ пациентов с первичным билиарным циррозом в редких случаях в начале лечения возможно усиление клинических симптомов, например, может усилиться зуд. В этом случае дозу препарата необходимо снизить до 250 мг (1/2 таблетки), а затем постепенно вновь увеличивать, как описано в разделе «Способ применения и дозы».\u003Cbr\u003E\nПри применении у пациентов с первичным склерозирующим холангитом: Длительная терапия высокими дозами УДХК (28-30 мг/кг/сут) пациентов с данной патологией может вызвать серьезные нежелательные явления.\u003Cbr\u003E\nУ пациентов с диареей следует уменьшить дозировку препарата. При персистирующей диарее следует прекратить лечение.\u003Cbr\u003E\nЖенщины детородного возраста могут принимать препарат, только если они используют надежные средства контрацепции. Рекомендуется использовать негормональные противозачаточные средства, либо пероральные контрацептивы с низким содержанием эстрогенов, поскольку гормональные пероральные контрацептивы могут усиливать камнеобразование в желчном пузыре. До начала лечения следует исключить возможную беременность."},{"name":"Взаимодействие","value":"Колестирамин, колестипол и антациды, содержащие алюминия гидроксид или смектит (алюминия оксид), снижают абсорбцию урсодезоксихолевой кислоты в кишечнике и таким образом уменьшают ее поглощение и эффективность. Если же использование препаратов, содержащих хотя бы одно из этих веществ, все же является необходимым, их нужно принимать минимум за 2 ч до приема препарата Урсофальк.\nУДХК может влиять на поглощение циклоспорина из кишечника. Поэтому у больных, одновременно принимающих циклоспорин, необходимо определять концентрацию циклоспорина в крови и в случае необходимости корректировать дозу циклоспорина.\nУДХК может снижать всасывание ципрофлоксацина.\nВ клиническом исследовании с участием здоровых добровольцев одновременное применение УДХК (500 мг/сут) и розувастатина (20 мг/сут) приводило к небольшому повышению уровня розувастатина в плазме крови. Клиническая значимость этого взаимодействия в том числе в отношении других статинов неизвестна.\nДоказано, что УДХК снижает максимальную концентрацию и площадь под фармакокинетической кривой «концентрация-время» антагониста кальция нитрендипина. В случае одновременного применения нитрендипина и УДХК рекомендуется тщательный мониторинг. Может потребоваться увеличение дозы нитрендипина. Кроме того, сообщалось о снижении терапевтического эффекта дапсона.\nЭти сведения, а также данные, полученные in vitro, позволяют предположить, что УДХК может индуцировать изоферменты CYP3A. Тем не менее, результаты контролируемых клинических исследований свидетельствуют о том, что УДХК не оказывает выраженного индуцирующего влияния на изофермент CYP3A.\nЭстрогены, гиполипидемические лекарственные средства, такие как клофибрат, увеличивают секрецию холестерина в печени и могут снижать литолитический эффект УДХК."},{"name":"Регистрационный номер","value":"ЛП-003568"},{"name":"Дата государственной регистрации","value":"20.09.2021"},{"name":"Владелец регистрационного удостоверения","value":"Dr. Falk Pharma","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:16003163"]}}},{"name":"Изготовитель","value":"Losan Pharma"},{"name":"Фасовщик","value":"Losan Pharma"},{"name":"Страна бренда","value":"Германия"},{"name":"Страна-производитель","value":"Германия"},{"name":"Название препарата","value":"Урсофальк","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["17796364:18012122"]}}},{"name":"Срок годности","value":"48 мес."}]}},"fullSpecsGrouped":{"7943804868871560272":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"печень, пищеварительная система"},{"name":"Назначение","value":"билиарный рефлюкс-гастрит, билиарный цирроз печени, дискинезия желчевыводящих путей, муковисцидоз, растворение мелких и средних холестериновых камней при функционирующем желчном пузыре, холангит, хронические гепатиты"},{"name":"Показания к применению","value":"Растворение холестериновых камней желчного пузыря размером не более 15 мм в диаметре при нормальной сократительной способности желчного пузыря.\u003Cbr\u003E\nВ составе комплексной терапии:\u003Cbr\u003E\nПервичный билиарный цирроз при отсутствии признаков декомпенсации;\u003Cbr\u003E\nЛечение билиарного рефлюкс-гастрита;\u003Cbr\u003E\nПервичный склерозирующий холангит;\u003Cbr\u003E\nНеалкогольный стеатогепатит;\u003Cbr\u003E\nМуковисцидоз (в составе комплексной терапии) у взрослых и детей в возрасте старше 6 лет."},{"name":"Противопоказания","value":"Гиперчувствительность к урсодезоксихолевой кислоте или другим желчным кислотам, а также к вспомогательным веществам препарата;\u003Cbr\u003E\nРентгеноконтрастные (кальцифицированные) камни в желчном пузыре; нарушение сократимости желчного пузыря;\u003Cbr\u003E\nОстрое воспаление желчного пузыря и желчевыводящих путей;\u003Cbr\u003E\nОкклюзия желчных путей (закупорка общего желчного протока или пузырного протока),\u003Cbr\u003E\nЧастые эпизоды желчной колики\u003Cbr\u003E\nДетский возраст до 3 лет (для данной лекарственной формы);\u003Cbr\u003E\nЦирроз печени в стадии декоменсации;\u003Cbr\u003E\nТяжелая печеночная и/или почечная недостаточность.\u003Cbr\u003E\nПедиатрическая популяция\u003Cbr\u003E\nНеудачная портоэнтеростомия или без восстановления нормального оттока желчи у детей с атрезией желчевыводящих путей."},{"name":"Состав","value":"В одной таблетке, покрытой пленочной оболочкой, содержится:\u003Cbr\u003E\nАктивное вещество: Урсодезоксихолевая кислота - 500 мг\u003Cbr\u003E\nВспомогательные вещества: целлюлоза микрокристаллическая, повидон К25, кросповидон (тип А), тальк, магния стеарат, кремния диоксид коллоидный, полисорбат.\u003Cbr\u003E\nПленочная оболочка: гипромеллоза, тальк, макрогол 6000."},{"name":"Действующее вещество","value":"Урсодезоксихолевая кислота"},{"name":"Способ применения и дозы","value":"Для пациентов, которые не могут проглотить препарат Урсофальк таблетки, покрытые пленочной оболочкой 500 мг, или с массой тела менее 47 кг рекомендуется применять препарат Урсофальк в капсулах или суспензии. Таблетки, покрытые пленочной оболочкой, следует проглатывать целиком, запивая жидкостью. Их следует принимать регулярно.\u003Cbr\u003E\nДетям до трех лет и пациентам с затруднением проглатывания рекомендуется принимать Урсофальк в форме суспензии.\u003Cbr\u003E\nРастворение холестериновых желчных камней\u003Cbr\u003E\nРекомендуемая доза составляет 10 мг урсодезоксихолевой кислоты на 1 кг массы тела в сутки.\u003Cbr\u003E\nДля растворения желчных камней обычно требуется 6-24 месяцев. Если после 12 месяцев лечения размер камней не уменьшается, то лечение следует прекратить.\u003Cbr\u003E\nЭффективность лечения следует оценивать каждые 6 месяцев при ультразвуковом исследовании или рентгенографии. В ходе промежуточного обследования следует оценить, не произошло ли обызвествление камней за истекший период. В случае обызвествления камней, лечение следует прекратить.\u003Cbr\u003E\nВ составе комплексной терапии:\u003Cbr\u003E\nЛечение первичного билиарного цирроза\u003Cbr\u003E\nСуточная доза зависит от массы тела и варьирует от 11/2 до 31/2 таблеток (14 ± 2 мг урсодезоксихолевой кислоты на 1 кг массы тела).\u003Cbr\u003E\nВ течение первых 3 месяцев лечения, суточную дозу следует разделить на несколько приемов. После улучшения функциональных показателей печени, можно перейти на однократный прием суточной дозы в вечернее время.\u003Cbr\u003E\nПрименение препарата Урсофалька для лечения первичного билиарного цирроза может продолжаться в течение неограниченного времени.\u003Cbr\u003E\nУ пациентов с первичным билиарным циррозом в редких случаях клинические симптомы могут ухудшиться в начале лечения, например, может участиться зуд. В этом случае лечение следует продолжить, принимая по /г таблетке ежедневно, далее следует постепенно повышать дозу (увеличивая суточную дозу еженедельно на ½ таблетки) до тех пор, пока вновь не будет достигнут рекомендованный режим дозирования.\u003Cbr\u003E\nЛечение билиарного рефлюкс-гастрита\u003Cbr\u003E\nПо 250 мг (1/2 таблетки) ежедневно вечером перед сном.\u003Cbr\u003E\nКурс лечения от 10-14 дней до 6 месяцев, при необходимости - до 2 лет.\u003Cbr\u003E\nПервичный склерозирующий холангит - суточная доза 12-15 мг/кг в 2-3 приема. Также было показано, что при дозе 20 мг/кг в сутки улучшается гистология и функциональные тесты печени у пациентов с ПСХ.\u003Cbr\u003E\nНеалкоголъный стеатогепатит - средняя суточная доза 10-15 мг/кг в 2-3 приема. Длительность терапии составляет от 6-12 месяцев и более.\u003Cbr\u003E\nМуковисцидоз (в составе комплексной терапии) у взрослых и детей в возрасте старше 6 лет: 20 мг/кг/сут в 2-3 приема с последующим увеличением до 30 мг/кг/сут при необходимости."},{"name":"Побочные действия","value":"Оценка нежелательных явлений основана на следующей классификации:\u003Cbr\u003E\nОчень частые (≥1/10)\u003Cbr\u003E\nЧастые (≥1/100 - \u003C1/10)\u003Cbr\u003E\nНечастые (≥1/1000 - \u003C1/100)\u003Cbr\u003E\nРедкие (≥1/10000-\u003C1/1000)\u003Cbr\u003E\nОчень редкие (\u003C1/10000).\u003Cbr\u003E\nНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003E\nВ клинических исследованиях на фоне лечения урсодезоксихолевой кислотой часто наблюдались неоформленный стул или диарея.\u003Cbr\u003E\nНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003E\nВ очень редких случаях на фоне лечения урсодезоксихолевой кислотой может произойти кальцинирование желчных камней.\u003Cbr\u003E\nПри лечении развитых стадий первичного билиарного цирроза, в очень редких случаях наблюдалась декомпенсация цирроза печени, которая регрессирует после отмены препарата.\u003Cbr\u003E\nНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003E\nВ очень редких случаях могут наблюдаться аллергические реакции, в том числе крапивница.\u003Cbr\u003E\nЕсли любое из указанных нежелательных явлений усугубляется, или Вы заметили другие неуказанные нежелательные явления, пожалуйста, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Небольшое количество УДХК содержится в желчи.\nПосле приема внутрь УДХК снижает насыщение холестерина желчи, ингибируя абсорбцию холестерина в кишечнике и снижая его секрецию в желчь. Предположительно в результате диспергирования холестерина и образования жидких кристаллов происходит постепенное растворение холестериновых камней в желчном пузыре.\nСогласно современным представлениям считается, что действие УДХК при заболеваниях печени и холестатических заболеваниях связано с относительным обменом липофильных, подобных детергентам, токсичных желчных кислот на гидрофильные, цитопротекторные, нетоксичные УДХК, что приводит к улучшению секреторной функции гепатоцитов и к иммунорегуляторным процессам.\nПедиатрическая популяция\nМуковисцидоз (кистозный фиброз)\nСогласно данным клинических отчетов, имеется многолетний опыт (до 10 лет и более) лечения урсодезоксихолевой кислотой педиатрических больных, страдающих гепатобилиарной болезнью, связанной с муковисцидозом (CFAHD). Имеются данные о том, что терапия урсодезоксихолевой кислотой способна снижать пролиферацию желчных протоков, замедлять развитие повреждений, выявляемых при гистологическом исследовании, и даже способствовать обратному развитию изменений гепатобилиарной системы в случае, если терапия начинается на ранних стадиях CFAHD. В целях оптимизации эффективности лечения терапию урсодезоксихолевой кислотой следует начинать как можно раньше после установления диагноза CFAHD."},{"name":"Фармакологическая группа","value":"гепатопротекторы"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 3 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25°С. Хранить в недоступном для детей месте.\u003Cbr\u003E"},{"name":"Передозировка","value":"В случае передозировки возможна диарея. В целом, другие симптомы передозировки маловероятны, поскольку с увеличением дозы урсодезоксихолевой кислоты ее абсорбция снижается, а выведение с каловыми массами увеличивается.\u003Cbr\u003E\nСпецифическое лечение не требуется, последствия диареи лечатся симптоматически с восстановлением водно-электролитного баланса."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003E\nДанные об использовании урсодезоксихолевой кислоты у беременных женщин носят ограниченный характер или отсутствуют. Исследования на животных показали наличие репродуктивной токсичности на ранней стадии беременности. Во время беременности Урсофальк не должен применяться во время беременности, за исключением случаев, когда это явно необходимо.\u003Cbr\u003E\nГрудное вскармливание\u003Cbr\u003E\nСогласно данным нескольких документально подтвержденных случаев, уровень урсодезоксихолевой кислоты в грудном молоке у женщин очень низок и поэтому возникновение нежелательных реакций у детей при грудном вскармливании не ожидается."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"УДХК не оказывает влияния на способность управлять транспортными средствами и механизмами или же это влияние минимальное."},{"name":"Особые указания","value":"Прием препарата Урсофальк должен осуществляться под наблюдением врача. В течение первых 3 месяцев лечения следует контролировать функциональные показатели печени ACT, АЛТ и гамма-глутамилтранспептидазу каждые 4 недели, а затем каждые 3 месяца. Такой мониторинг позволит на раннем этапе выявить потенциальное ухудшение состояния печени, особенно у пациентов с поздней стадией ПБЦ. Кроме того, так можно быстро определить, реагирует ли пациент с первичным билиарным циррозом на проводимое лечение.\u003Cbr\u003E\nПри применении у пациентов для растворения холестериновых желчных камней:\u003Cbr\u003E\nДля того, чтобы оценить прогресс в лечении и для своевременного выявления признаков кальциноза камней в зависимости от размера камней, желчный пузырь следует визуализировать (пероральная холецистография) с осмотром затемнений в положении «стоя» и «лежа на спине» (ультразвуковое исследование) через 6-10 месяцев после начала лечения.\u003Cbr\u003E\nЕсли желчный пузырь невозможно визуализировать на рентгеновских снимках или в случаях кальциноза камней, слабой сократимости желчного пузыря или частых приступов колик, препарат Урсофальк применять не следует.\u003Cbr\u003E\nПри лечении пациентов на поздних стадиях первичного билиарного цирроза: Крайне редко отмечались случаи декомпенсации цирроза печени после прекращения терапии.\u003Cbr\u003E\nУ пациентов с первичным билиарным циррозом в редких случаях в начале лечения возможно усиление клинических симптомов, например, может усилиться зуд. В этом случае дозу препарата необходимо снизить до 250 мг (1/2 таблетки), а затем постепенно вновь увеличивать, как описано в разделе «Способ применения и дозы».\u003Cbr\u003E\nПри применении у пациентов с первичным склерозирующим холангитом: Длительная терапия высокими дозами УДХК (28-30 мг/кг/сут) пациентов с данной патологией может вызвать серьезные нежелательные явления.\u003Cbr\u003E\nУ пациентов с диареей следует уменьшить дозировку препарата. При персистирующей диарее следует прекратить лечение.\u003Cbr\u003E\nЖенщины детородного возраста могут принимать препарат, только если они используют надежные средства контрацепции. Рекомендуется использовать негормональные противозачаточные средства, либо пероральные контрацептивы с низким содержанием эстрогенов, поскольку гормональные пероральные контрацептивы могут усиливать камнеобразование в желчном пузыре. До начала лечения следует исключить возможную беременность."},{"name":"Взаимодействие","value":"Колестирамин, колестипол и антациды, содержащие алюминия гидроксид или смектит (алюминия оксид), снижают абсорбцию урсодезоксихолевой кислоты в кишечнике и таким образом уменьшают ее поглощение и эффективность. Если же использование препаратов, содержащих хотя бы одно из этих веществ, все же является необходимым, их нужно принимать минимум за 2 ч до приема препарата Урсофальк.\nУДХК может влиять на поглощение циклоспорина из кишечника. Поэтому у больных, одновременно принимающих циклоспорин, необходимо определять концентрацию циклоспорина в крови и в случае необходимости корректировать дозу циклоспорина.\nУДХК может снижать всасывание ципрофлоксацина.\nВ клиническом исследовании с участием здоровых добровольцев одновременное применение УДХК (500 мг/сут) и розувастатина (20 мг/сут) приводило к небольшому повышению уровня розувастатина в плазме крови. Клиническая значимость этого взаимодействия в том числе в отношении других статинов неизвестна.\nДоказано, что УДХК снижает максимальную концентрацию и площадь под фармакокинетической кривой «концентрация-время» антагониста кальция нитрендипина. В случае одновременного применения нитрендипина и УДХК рекомендуется тщательный мониторинг. Может потребоваться увеличение дозы нитрендипина. Кроме того, сообщалось о снижении терапевтического эффекта дапсона.\nЭти сведения, а также данные, полученные in vitro, позволяют предположить, что УДХК может индуцировать изоферменты CYP3A. Тем не менее, результаты контролируемых клинических исследований свидетельствуют о том, что УДХК не оказывает выраженного индуцирующего влияния на изофермент CYP3A.\nЭстрогены, гиполипидемические лекарственные средства, такие как клофибрат, увеличивают секрецию холестерина в печени и могут снижать литолитический эффект УДХК."},{"name":"Регистрационный номер","value":"ЛП-003568"},{"name":"Дата государственной регистрации","value":"20.09.2021"},{"name":"Владелец регистрационного удостоверения","value":"Dr. Falk Pharma"},{"name":"Изготовитель","value":"Losan Pharma"},{"name":"Фасовщик","value":"Losan Pharma"},{"name":"Страна бренда","value":"Германия"},{"name":"Страна-производитель","value":"Германия"},{"name":"Название препарата","value":"Урсофальк"},{"name":"Срок годности","value":"48 мес."}]}],"transitionId":"tr_2633743735237217804"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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2 049 ₽

Скидка: 11%
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Вместо:2 302 ₽
  • 11-13 июня, самовывоз • 0 ₽
POLZAru
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  • Урсосан таб. п/о плен., 500 мг, 100 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9ja68okn045/toggleWishlist":{"skuId":"228092197","productId":1400799542,"offerId":"fFk6McczKquZ8yXTLR-J3w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhYjWnqmup8cqEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUItoL6mwUQpdLhbBik3dAHINrZwQc=","sign":"HYaSZK2OoBvkxMAKj8AQ2tHudqGNA4UJ16Z9u6M5rVQ="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9ja68okn045/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Урсосан таб. п/о плен., 500 мг, 100 шт.

    Рейтинг товара: 4.8 из 5
    на основе 88 оценок
    Цена 3 601 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9ja68okn045/addToCartButton":{"offerId":"fFk6McczKquZ8yXTLR-J3w","skuId":"228092197","pendingCartItem":{"productId":1400799542,"offerId":"fFk6McczKquZ8yXTLR-J3w","showPlaceId":"OTNDnItfwRMjN9MRHuEMMmkRG22cEVbeJmt0Ry4TrNf-k_kRTg5AacQ55exj5rxMRVO32lU0x25VWC_vqd9H6nPCLA_ulC0Ggrb2RTRNuaiDi43S8eXk5eZJYBHSFBlZA2IG7nSvnbQ0o0ddeeJtCSi4vpDM8oubGv54q05k22ABuTmIoLv6e1B3Rkb7jTH5WuLeo7dS7s_WI-JlcFm7vw,,","feeShow":"OTNDnItfwRMjN9MRHuEMMmkRG22cEVbeJmt0Ry4TrNf-k_kRTg5AacQ55exj5rxMRVO32lU0x25VWC_vqd9H6nPCLA_ulC0Ggrb2RTRNuaiDi43S8eXk5eZJYBHSFBlZA2IG7nSvnbQ0o0ddeeJtCSi4vpDM8oubGv54q05k22ABuTmIoLv6e1B3Rkb7jTH5WuLeo7dS7s_WI-JlcFm7vw,,","skuId":"228092197","shopId":77075781,"price":{"applicablePriceDiscounts":[],"value":"3601","currency":"RUR"},"hid":"15756506","name":"Урсосан таб. п/о плен., 500 мг, 100 шт.","label":"vmnolstwa4n","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4590616,"key":"img_id1348328051850159838.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCsK6Lj3mUTlbBJLTvevmjvDxkzhyHVOcIYs3z-ZNSVNpipMtSKurfCsdiypoumg45p10aHIvyEft69O2DwVLLbQnfO07m1RVjtVPUONsrDHVKdmpvRjRAWCX237bHO9A469IDZf6lcZRXUGbD36fBWTOdXA-SHUfQ_j4HVx05xoTm778ELDhWgUNaUi6T2DGOM0o9JG7mwRzZje3SVK26IQc9wznV56SypDS2MOC6clnOxGjRQfMRLzSMMW0XjTsrH23mfXpMVIdQylJ2geAGGe1A_Bp3UQA4gqHgu4ujMF5bNX8a_3Yi1AVxGfHXx3OHU2xI7IfIU4e13wN7WLtvhhjXPG9Umt8rWIs70cJerLrm0h5oL6YlCU9g8wx6rdzYnwx31ThwrNzYUvnrU7_o3nufH_2vXhyqRN_v4TfCMPWrF5DIRjV5l7uovBL4TVx7cL9QkPcuqFBTYWtQAW0o0kshHQSfTSIWatIA8HD-UmhThXGNbIBEW8rXB1surM_FtMbQ6xZoMRmdBPyJvv5v9eAkUjS3TirF7HruKSqrnvUiqWDMswaxlPiqCl_kO-oZmxfIOYOqGveUleMwgBcM2Bxao57261LJn82dUxYrkqOk4DPJkvlmDQ9120fefS5np-4wlpxi6fyEMKcR52Q1YlPIn8t21iTD5P3U2uz8kUycKb3xQ-1gLvtHKTiIteFHF76cNEs_4Kv99Zd_hx6JiqK3XaBiD5x2bfHJL8Il9Q-Ku9lVSiswcfqGrC3PaCN3gImS_KIT8DCihXGo0n5nJlijk7hHtoU2-eDWJ-L2rdfNk9qRWSdq9f5y3Q0lxTdsIYFwcrq7piH9vjfbKzzXxcedc_qvXm-4hDk136FZy_BcJsPMdjlwLaqRAUejDpYS9AcuvuE_rqYNlsCYjlwbgmEMRF3I5MKiBkQrvzm4Gd8g3CL4aEjCXGam8GQ7keDmsSS4LqNnUJ9xq08DW3gBfeDZwBzJuzSZuzru5-9X3xwfROBZvz2DE4bQNpg_HqiZIeqPib2UcMPb46SzAnPeGmleE3fgx75Ktl92XRzOAviz4WGwK4b5eSAgbt6UEvtMDDepC0CtmIDCIgifDeWw9qtkBpt8HVHMeFwFIwSh-Sk-wjcSwr1QM7BB69fO_YAGS3USrbnmWtnO4g2IWWzDZsChgFACbOtecUecBS4JRm_0NyEeLwwG8UTvips0c5zLbYZxZcYyvcIMmP5VjVIuOups2ks0cYsVIUkIwL7_yXrTcaV7IAmwayRR0Ab0Y8BNqavoJvO5f1ndltL0ek8MK1wtMfkiYjZLB1dPlzFCzFHm-pqqzYCIsKqrq_yQTm5p8OC1zAYv_F4mfbPLLkY-RXyRwSTXfSFBLv3iOzM1XKmiMJCRgZGEyvCVb9gejEWn-waG-9IzhOAZkCC34dZXvEd_HbeeorkSoszt8EtRxCO_02MXUqM_c4FPZSZyeYhwYOxqhFpF5_KsSz4EO0DA4c_SyyahuFBuBbba8iXvilcKyG23SGZdX6Gpz6thL67pspYmohU6BxurY53ygVDC_CIK6cRvjlLd8VelWL6onmbNlP1Ir1UpigzeARuYyfiBIvNFFEtK7BP2jdYkEteNIMYWyQrifLVVg-G2AIj5GbVgJXJsrLd-pU05R6D6ivEFassNIpArjiwcZ0mG1-993B7x91QW_Fba11OywF_QML10DFUjvJALl-oqRbFP2up8QI6ti8QmsJzKdjK_y8UiRAQO0kO3oPEfckQ5Bh2-VFgd65U2J6c6tO8wDv8_P--vNZWIWklrBB-7E87N3bcMQgme6v71BM-vbIWU4SGN7lVljd0txutORtxO2HYXzpQvwxFucnx8v0Tyc0T2f5rS9gRB2dGf_WccOM8CBn8fdei-nXyafcvCFiMtaPa3aGmgqvJrjNYsIw9o5NXQ1GwTuRRw56nIN8SloljyXc9BOmSDUuZ1FvGE_p_46uUCTdg7-LRr1T7OLiv914VWps8KRHP33GsxLHt5PdF0kILRPA85JR85FMvyDD6X7UIdYJLbCo_QnxGDbuPHQMNE7BtFrQHfufAKNTj1TeriQ73vcKtSm6bhEv7lW75qqx5QLGp0RCchmed7jWJX7ExS9fxEOIicdMyJ89W1lQ81UvZ0dY__or933i6wpPZSsSNTOgw4cTpwNMLoZCiEMhRuJMTI40quktOOFJtKyw-uRbLbaEdWRuggWZH3DwIk2rPaa9oXeNJTcDQQYI2XphfdKbitcikH2ei0o_NoXg9VOZSmjTDcgTWPjtpb_Rg5Dxh81PtdfAtc09OqhdinVp4A9QCN90sqYqk6a2phFfP_1Fc4WrAoVBD4Qdy9LKMyiKhzPniHTRrQxxLAVi9psHU3o9fwjbAPMWHkZ1EAiGjPd-LZcxodFyztfDHONf7946SwVZ401ur23Hr_8iSdiU2ZT7wG59pU9pZdxr9C3o4f5gyg-4NI3PhLaJBwXwzA5oqaJ7DGdFW661P-8wNCEHpAXmGNxKyL82AmQpzYgBaInjnx-Jf3tf5g2kTQcIAwdRU4UPYu5L5CHvIfKFWCXNFiiBuNCQ6P1Hcaf3aIuxlisi15drOkBcdf9XgNRGAzorO5-MlqXzc4dErvOdBt7JdUvw1ByPhSxpNONMrQRm0DfBo6K3WvKFc58tYEHbsGCr4RHSfZC8yk2PoEkQe-nM0NHuO1aytaLNItJlGsEp-REYQUX4vJUnCMrD7AB0Xrn4HiQHffOueMhJqUmUGTBjbL3yQf2OZYA6dkva0tTctbgXt-AalQir43HR8JLphG8lUHJ1vBSbPa0wubROyRw1NI15lJTzYZvyTRThmRcRebOIxjccO3qxOo7MORRPk0bckQrMsr6VqJl7ITRvYlYk1CDzk9APBfS-0H4g8V6L_84gCkw7pnt1G55WyR07oI4IBn1qAnqsddRj9moyXO-zJ_sg8a1ooV-zrn2af3Vow-25voJ6kBwyQbLLECQ4zsXPOJw5id3dDnAqAWmIve1lMiewPJCqUCdWrX6kPZAw_zvryIOl60JZxAePp4r3bhZJxNf8MgRN9NphGb2Id8aY-cbv1Y4ujZBmjawkYMVE1yrYvGWHdIUKzxQGv69T9YYB9PqJJnR1hF3vB3L0DPmtb4N9TWzupiOQD64E5-LCG1dHoYc7mfsUc0Top0p5p-3coI-ZIDCKVxapanLUVHHb_HsPVbMuv4DMKjec42qU4w0yyun4sejoQqrtHsditkyn5VqCWo3kvWDni4qCL2Z0mPPQ4cXq5t29DgcrgNfU4XyvwO4cEuw909yQQUNJAEpnQe2ngUvcfY6j65pKFhHCwjrqw6RYp1IzUhF4uazXGkrIarWLnQEh-gVi1bJYU5XqLBIcL4_zGsku4QYGZp3pecLNJasp_lfnGtwlSiw,,/b64e=1/sign=0bd023003982ebad26e652547360c253/keyno=MARKET_1/*","showUid":"17179627583940642969406002","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhYjWnqmup8cqEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUItoL6mwUQpdLhbBik3dAHINrZwQc=","sign":"HYaSZK2OoBvkxMAKj8AQ2tHudqGNA4UJ16Z9u6M5rVQ="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhYjWnqmup8cqEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUItoL6mwUQpdLhbBik3dAHINrZwQc=","sign":"HYaSZK2OoBvkxMAKj8AQ2tHudqGNA4UJ16Z9u6M5rVQ="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-9ja68okn045/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Урсодез капс., 500 мг, 30 шт.
    –10 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yu0hoigaql8/toggleWishlist":{"skuId":"187020818","productId":1400799481,"offerId":"VYxkTP-eany1Xw_Xnj8dxQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhYjWnqmup8cqEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI+YH6mwUQkuyWWRiu3tAHINrZwQc=","sign":"5fEIrnQB8DTcpUiXPmMAs3leIvstY2Phv3Lv4Ko45W0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yu0hoigaql8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Урсодез капс., 500 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 48 оценок
    Цена 802 ₽ вместо 890
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  • Урсодезоксихолевая кислота-Вертекс капс., 250 мг, 50 шт.
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    Урсодезоксихолевая кислота-Вертекс капс., 250 мг, 50 шт.

    Рейтинг товара: 4.9 из 5
    на основе 18 оценок
    Цена 774 ₽
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  • Урдокса таб. п/о плен., 500 мг, 50 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-r841akstww/toggleWishlist":{"skuId":"922400007","productId":1778171666,"offerId":"NeuK7pu3u7j1IfJOHLFA2A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhYjWnqmup8cqEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIkv7yzwYQh+rqtwMYsYu6CCDa2cEH","sign":"5gy8VKErdc+MXFOvbzkU84WNW89wSgk5hyMEUvwqlcg="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-r841akstww/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Урдокса таб. п/о плен., 500 мг, 50 шт.

    Рейтинг товара: 5 из 5
    на основе 14 оценок
    Цена 1 624 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-r841akstww/addToCartButton":{"offerId":"NeuK7pu3u7j1IfJOHLFA2A","skuId":"922400007","pendingCartItem":{"productId":1778171666,"offerId":"NeuK7pu3u7j1IfJOHLFA2A","showPlaceId":"OTNDnItfwRMjN9MRHuEMMmkRG22cEVbe5rS_6idgGMh0dH97Me8OB7DJKUE8WKxsOD2axVSoir6PgHNaNw4F7v6io83H1u3DbBsGgvmwpuI-2EdlnFlr7FYTSpAlqQQqk8KVSLQqMuxCxdC2QKD9PYwJ-K2sRKV41GIdZKBZpb_chtlHEAe96xhu_SqauhjsPScsnFsnQc__VXTLgfDQag,,","feeShow":"OTNDnItfwRMjN9MRHuEMMmkRG22cEVbe5rS_6idgGMh0dH97Me8OB7DJKUE8WKxsOD2axVSoir6PgHNaNw4F7v6io83H1u3DbBsGgvmwpuI-2EdlnFlr7FYTSpAlqQQqk8KVSLQqMuxCxdC2QKD9PYwJ-K2sRKV41GIdZKBZpb_chtlHEAe96xhu_SqauhjsPScsnFsnQc__VXTLgfDQag,,","skuId":"922400007","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"1624","currency":"RUR"},"hid":"15756506","name":"Урдокса таб. п/о плен., 500 мг, 50 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  • Урсосан форте таб., 500 мг, 50 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xy5sargs9h/toggleWishlist":{"skuId":"102095827895","productId":1897676911,"offerId":"Sdp5N10JPtB0XxPuzKD-Ng","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhYjWnqmup8cqEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI74DxiAcQt+eKq/wCGKTd0Acg2tnBBw==","sign":"phHXxd0s3jtGx0h0EULvY/4GXYH7XoupljsbQdfq84Q="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-xy5sargs9h/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Урсосан форте таб., 500 мг, 50 шт.

    Рейтинг товара: 5 из 5
    на основе 37 оценок
    Цена 1 866 ₽
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  • Урсосан капс., 250 мг, 10 шт.
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    Урсосан капс., 250 мг, 10 шт.

    Рейтинг товара: 4.9 из 5
    на основе 59 оценок
    Цена 170 ₽
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  • Урсодезоксихолевая кислота капс., 250 мг, 50 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-137a7fuoayj/toggleWishlist":{"skuId":"101770901179","productId":1756207489,"offerId":"4aEFWv7z1yxOZc8I6-3ysw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhYjWnqmup8cqEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIgbO2xQYQu+2SkPsCGNra1BEg2tnBBw==","sign":"5EIPrVwRMuCeoS5TpYQNUeyrbLWgI5AlbGjkZrRw9c4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-137a7fuoayj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Урсодезоксихолевая кислота капс., 250 мг, 50 шт.

    Рейтинг товара: 4.8 из 5
    на основе 199 оценок
    Цена 533 ₽
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  • Салофальк таб. п/о кш/раств., 500 мг, 50 шт.
    –19 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-u3wc3ce8ncj/toggleWishlist":{"skuId":"227814449","productId":1400799522,"offerId":"xm6VNqbGpChuZYnpkRwHKA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhYjWnqmup8cqEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIooL6mwUQsdjQbBjb4NAHINrZwQc=","sign":"YizPgOBVSYVRKCy+xR7MnhodnGpioVMhiZOfOqtj+s0="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-u3wc3ce8ncj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Салофальк таб. п/о кш/раств., 500 мг, 50 шт.

    Рейтинг товара: 4.9 из 5
    на основе 26 оценок
    Цена 908 ₽ вместо 1 126
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Инструкция

Показания к применению

Растворение холестериновых камней желчного пузыря размером не более 15 мм в диаметре при нормальной сократительной способности желчного пузыря.
В составе комплексной терапии:
Первичный билиарный цирроз при отсутствии признаков декомпенсации;
Лечение билиарного рефлюкс-гастрита;
Первичный склерозирующий холангит;
Неалкогольный стеатогепатит;
Муковисцидоз (в составе комплексной терапии) у взрослых и детей в возрасте старше 6 лет.

Противопоказания

Гиперчувствительность к урсодезоксихолевой кислоте или другим желчным кислотам, а также к вспомогательным веществам препарата;
Рентгеноконтрастные (кальцифицированные) камни в желчном пузыре; нарушение сократимости желчного пузыря;
Острое воспаление желчного пузыря и желчевыводящих путей;
Окклюзия желчных путей (закупорка общего желчного протока или пузырного протока),
Частые эпизоды желчной колики
Детский возраст до 3 лет (для данной лекарственной формы);
Цирроз печени в стадии декоменсации;
Тяжелая печеночная и/или почечная недостаточность.
Педиатрическая популяция
Неудачная портоэнтеростомия или без восстановления нормального оттока желчи у детей с атрезией желчевыводящих путей.

Способ применения и дозы

Для пациентов, которые не могут проглотить препарат Урсофальк таблетки, покрытые пленочной оболочкой 500 мг, или с массой тела менее 47 кг рекомендуется применять препарат Урсофальк в капсулах или суспензии. Таблетки, покрытые пленочной оболочкой, следует проглатывать целиком, запивая жидкостью. Их следует принимать регулярно.
Детям до трех лет и пациентам с затруднением проглатывания рекомендуется принимать Урсофальк в форме суспензии.
Растворение холестериновых желчных камней
Рекомендуемая доза составляет 10 мг урсодезоксихолевой кислоты на 1 кг массы тела в сутки.
Для растворения желчных камней обычно требуется 6-24 месяцев. Если после 12 месяцев лечения размер камней не уменьшается, то лечение следует прекратить.
Эффективность лечения следует оценивать каждые 6 месяцев при ультразвуковом исследовании или рентгенографии. В ходе промежуточного обследования следует оценить, не произошло ли обызвествление камней за истекший период. В случае обызвествления камней, лечение следует прекратить.
В составе комплексной терапии:
Лечение первичного билиарного цирроза
Суточная доза зависит от массы тела и варьирует от 11/2 до 31/2 таблеток (14 ± 2 мг урсодезоксихолевой кислоты на 1 кг массы тела).
В течение первых 3 месяцев лечения, суточную дозу следует разделить на несколько приемов. После улучшения функциональных показателей печени, можно перейти на однократный прием суточной дозы в вечернее время.
Применение препарата Урсофалька для лечения первичного билиарного цирроза может продолжаться в течение неограниченного времени.
У пациентов с первичным билиарным циррозом в редких случаях клинические симптомы могут ухудшиться в начале лечения, например, может участиться зуд. В этом случае лечение следует продолжить, принимая по /г таблетке ежедневно, далее следует постепенно повышать дозу (увеличивая суточную дозу еженедельно на ½ таблетки) до тех пор, пока вновь не будет достигнут рекомендованный режим дозирования.
Лечение билиарного рефлюкс-гастрита
По 250 мг (1/2 таблетки) ежедневно вечером перед сном.
Курс лечения от 10-14 дней до 6 месяцев, при необходимости - до 2 лет.
Первичный склерозирующий холангит - суточная доза 12-15 мг/кг в 2-3 приема. Также было показано, что при дозе 20 мг/кг в сутки улучшается гистология и функциональные тесты печени у пациентов с ПСХ.
Неалкоголъный стеатогепатит - средняя суточная доза 10-15 мг/кг в 2-3 приема. Длительность терапии составляет от 6-12 месяцев и более.
Муковисцидоз (в составе комплексной терапии) у взрослых и детей в возрасте старше 6 лет: 20 мг/кг/сут в 2-3 приема с последующим увеличением до 30 мг/кг/сут при необходимости.
Полная инструкция
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Урсофальк таб. п/о плен.
Урсофальк таб. п/о плен., 500 мг, 50 шт.
4.8
(26)
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Инструкция

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Вместо:2 302 ₽
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4.8
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