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Описание

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Линкомицин г/хл р-р д/ин., 300 мг/мл, 1 мл, 10 шт.

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5.0
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Коротко о товаре

Артикул Маркета
4236631609
Тип препарата
Назначение
Действующее вещество
Возраст
от 3 лет
Инструкция
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повышенная чувствительность к другим компонентам препарата, к клиндамицину; тяжелая печеночная и/или почечная недостаточность; беременность (за исключением случаев, когда это необходимо по \"жизненным\" показаниям), период грудного вскармливания, новорожденные (до 1 мес.)."},{"name":"Состав","value":"Действующее вещество: линкомицина гидрохлорида моногидрат (в пересчете на линкомицин) - 300,0 мг.\u003Cbr\u003EВспомогательные вещества: динатрия эдетат (этилендиаминтетрауксусной кислоты динатриевая соль) - 0,1 мг, 0,1 М раствор натрия гидроксида - до pH 6,0 мг, вода для инъекций - до 1 мл.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Линкомицин","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28709157"]}}},{"name":"Способ применения и дозы","value":"Внутривенно, внутримышечно.\u003Cbr\u003EСуточная доза для взрослых при парентеральном введении составляет 1,8 г, разовая - 0,6 г. При тяжелом течении инфекции суточная доза может быть увеличена до 2,4 г. Препарат вводят 3 раза в сутки с интервалами 8 часов.\u003Cbr\u003EДетям старше 1 месяца назначают внутривенно в суточной дозе 10-20 мг/кг, вне зависимости от возраста.\u003Cbr\u003EВнутривенно - только капельно, со скоростью 60-80 капель в минуту. Перед введением 2 мл препарата (0,6 г) разбавляют 250 мл раствора натрия хлорида 0,9%. Продолжительность лечения в зависимости от формы и тяжести заболевания составляет 7-14 дней (при остеомиелите - 3 недели и более).\u003Cbr\u003EПри длительных или повторных курсах лечение следует проводить под контролем функции печени и почек.\u003Cbr\u003EПациентам с почечно-печеночной недостаточностью линкомицин назначают парентерально в суточной дозе, не превышающей 1,8 г, с интервалами между введениями не менее 12 часов.\u003Cbr\u003E"},{"name":"Побочные действия","value":"Нарушения со стороны крови и лимфатической системы: обратимые лейкопения, тромбоцитопеническая пурпура, нейтропения, агранулоцитоз, апластическая анемия и панцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: зуд, крапивница, сыпь, эксфолиативный дерматит, везикуло-буллезный дерматит, ангионевротический отек, анафилактический шок, мультиформная эритема (синдром Стивенса-Джонсона), сывороточная болезнь.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: шум в ушах, вертиго. Нарушения со стороны желудочно-кишечного тракта: тошнота, рвота, антибиотикассоциированная диарея, боль в животе, зуд ануса, глоссит, стоматит, при длительном применении - кандидоз желудочно- кишечного тракта, псевдомембранозный колит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: желтуха, транзиторная гипербилирубинемия, повышение активности \"печеночных\" трансаминаз.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: нарушение функции почек (азотемия, олигурия, протеинурия).\u003Cbr\u003EНарушения со стороны половых органов и молочной железы: вагинит.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: при внутривенном введении - тромбофлебит, при внутримышечном введении - местное раздражение, болезненность, образование уплотнения и стерильного абсцесса в месте инъекции.\u003Cbr\u003EПри быстром внутривенном введении - снижение артериального давления, головокружение, головная боль, сонливость, общая слабость, расслабление скелетной мускулатуры, остановка дыхания и сердца.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Антибиотик, продуцируемый Streptomyces lincolnensis, оказывает бактериостатическое действие. Подавляет белковый синтез бактерий вследствие обратимого связывания с 50S субъединицей рибосом, нарушает образование пептидных связей.\u003Cbr\u003EЧувствительны in vivo: Staphylococcus aureus (пенициллиназопродуцирующие и непродуцирующие штаммы), Staphylococcus epidermidis, Streptococcus pneumoniae.\u003Cbr\u003EЧувствительны in vitro: аэробные грамположительные микроорганизмы - Streptococcus pyogenes, Streptococcus spp. группы viridans, Corynebacterium diphtheriae; анаэробные грамположительные микроорганизмы - Propionibacterium acnes, Clostridium tetani, Clostridium perfringens.\u003Cbr\u003EЭффективен в отношении Staphylococcus spp., устойчивых к пенициллину, тетрациклину, хлорамфениколу, стрептомицину, цефалоспоринам (30% Staphylococcus spp.,устойчивых к эритромицину, имеют перекрестную устойчивость к линкомицину).\u003Cbr\u003EНе действует на Enterococcus spp. (в т.ч. Enterococcus faecalis); Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae и др. грамотрицательные бактерии, а также грибы, вирусы, простейшие.\u003Cbr\u003EОптимум действия находится в щелочной среде (pH 8-8,5). Устойчивость к линкомицину развивается медленно. В высоких дозах обладает бактерицидным эффектом.\u003Cbr\u003EСуществует перекрестная резистентность между линкомицином и клиндамицином.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"антибиотики"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["35947170:36763748"]}}},{"name":"Минимальный возраст применения","value":"от 3 лет"},{"name":"Условия хранения","value":"В защищенном от света месте при температуре от 5 до 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте.\u003Cbr\u003E"},{"name":"Передозировка","value":"Симптомы: усиление выраженности проявлений дозозависимых нежелательных реакций.\u003Cbr\u003EЛечение: симптоматическая терапия, плохо удаляется при гемо- и перитонеальном диализе.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано применять во время беременности (за исключением случаев, когда это необходимо по \"жизненным\" показаниям) и в период грудного вскармливания (на время лечения грудное вскармливание необходимо прекратить)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При применении линкомицина нельзя исключить вероятность появления головокружения и расслабления скелетной мускулатуры, поэтому вождение автотранспорта и другие виды деятельности, требующие повышенного внимания и скорости реакции, не рекомендуются."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EГрибковые заболевания кожи, слизистой оболочки полости рта, влагалища; миастения; одновременное применение с лекарственными препаратами, блокирующими нервно-мышечную проводимость; сахарный диабет; печеночная/почечная недостаточность средней степени тяжести; заболевания желудочно-кишечного тракта, особенно колиты, в анамнезе.\u003Cbr\u003EПри применении линкомицина следует учитывать официальные национальные рекомендации по надлежащему применению антибактериальных препаратов, а также чувствительность патогенных микроорганизмов в конкретной стране.\u003Cbr\u003EЛинкомицин следует назначать с осторожностью пациентам с заболеваниями желудочно-кишечного тракта, особенно колитами, в анамнезе.\u003Cbr\u003EСообщалось о случаях псевдомембранозного колита, развившегося спустя 2 месяца после приема антибактериальных препаратов, которые требуют назначения ионообменных смол (колестирамин), в тяжелых случаях показано возмещение потери жидкости, электролитов и белка, ванкомицин - внутрь, в суточной дозе 0,5-2 г (за 3-4 приема) в течение 10 дней или бацитрацин. Противопоказано применение препаратов, тормозящих перистальтику кишечника.\u003Cbr\u003EЛинкомицин не показан для терапии менингита, поскольку его концентрация в спинномозговой жидкости недостаточна для лечения менингита.\u003Cbr\u003EНе рекомендуется применять линкомицин у пациентов с сахарным диабетом за исключением случаев отсутствия альтернативного лечения, поскольку отсутствуют адекватные данные о терапии пациентов с эндокринными или метаболическими заболеваниями.\u003Cbr\u003EПериод полувыведения линкомицина может быть увеличен у пациентов с нарушениями функции печени и почек, поэтому следует соблюдать осторожность при назначении линкомицина пациентам с печеночной/почечной недостаточностью средней степени тяжести и контролировать концентрацию линкомицина в крови во время терапии высокими дозами линкомицина. У таких пациентов следует рассмотреть возможность уменьшения частоты введения препарата.\u003Cbr\u003EПрименение при тяжелой печеночной/почечной недостаточности противопоказано.\u003Cbr\u003EКак и при применении других противомикробных препаратов при применении линкомицина, особенно длительном, возможно развитие вторичной инфекции, связанной с ростом устойчивых к препарату микроорганизмов (особенно грибов), для исключения и подтверждения которой, следует проводить повторную оценку состояния пациента. Если во время терапии возникает вторичная инфекция, следует принять необходимые меры по ее лечению.\u003Cbr\u003EЛинкомицин следует применять с осторожностью у пациентов с имеющимися грибковыми заболеваниями, таким пациентам следует также назначать противогрибковую терапию.\u003Cbr\u003EПри применении линкомицина сообщалось о развитии тяжелых буллезных реакций, таких как синдром Стивенса-Джонсона. Пациентов следует информировать о том, что при развитии кожных реакций и/или поражений слизистых оболочек, необходимо немедленно проконсультироваться у врача прежде, чем продолжать лечение линкомицином.\u003Cbr\u003EПри применении линкомицина сообщалось о развитии аллергических реакций, которые могут прогрессировать до жизнеугрожающего состояния. В этих случаях следует прекратить применение линкомицина и начать проведение соответствующего лечения.\u003Cbr\u003EЛинкомицин характеризуется блокирующей нервно-мышечное проведение активностью и может усиливать мышечную слабость у пациентов с псевдопаралитической миастенией. Применение линкомицина у пациентов с установленным диагнозом псевдопаралитической миастении не рекомендуется.\u003Cbr\u003EСообщалось о случаях развития нейтропении и/или лейкопении на фоне лечения линкомицином, поэтому во время терапии рекомендуется периодический контроль анализа крови.\u003Cbr\u003EНа фоне длительного лечения необходим периодический контроль активности \"печеночных\" трансаминаз и функции почек. При выявлении нарушений следует рассмотреть возможность отмены препарата.\u003Cbr\u003EВо избежание развития асептического некроза вводить лучше глубоко внутримышечно. Внутривенно вводить без предварительного разведения нельзя.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Фармацевтически несовместим с канамицином, ампициллином, барбитуратами, теофиллином, кальция глюконатом, гепарином и магния сульфатом.\u003Cbr\u003EАнтагонизм - с эритромицином, пенициллинами, цефалоспоринами и хлорамфениколом, ампициллином и другими бактерицидными антибиотиками, синергизм - с аминогликозидами.\u003Cbr\u003EУсиливает действие лекарственных средств для ингаляционного наркоза, миорелаксантов и опиоидных анальгетиков, повышая риск нервно-мышечной блокады и остановки дыхания.\u003Cbr\u003EПри одновременном применении теофиллина с линкомицином, ингибиторами изоферментов цитохрома Р450, эффективность теофиллина может увеличиваться, что может потребовать снижения его дозы.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"P N001864/01-2002"},{"name":"Дата государственной регистрации","value":"23.04.2018"},{"name":"Владелец регистрационного удостоверения","value":"Дальхимфарм","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["34324371:35649313","7893318:13877405"]}}},{"name":"Изготовитель","value":"Дальхимфарм"},{"name":"Фасовщик","value":"Дальхимфарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Линкомицин","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["17796364:18036889"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"10157179688163487113":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Назначение","value":"абсцесс легкого, артрит, инфекции кожи и мягких тканей, инфекционно-воспалительные заболевания, вызванные чувствительными микроорганизмами, инфицированные раны и нарывы, наружный отит, остеомиелит, плеврит, послеоперационные инфекции, сепсис, средний отит, эмпиема, эндокардит"},{"name":"Органы и системы","value":"дыхательная система, кожа, костная система, кровеносная система, опорно-двигательная система, сердце, уши"},{"name":"Показания к применению","value":"Бактериальные инфекции, вызванные чувствительными к линкомицину микроорганизмами (прежде всего Staphylococcus spp. и Streptococcus spp., особенно микроорганизмами, устойчивыми к пенициллинам, а также при аллергии к пенициллинам): сепсис, подострый септический эндокардит, абсцесс легкого, эмпиема плевры, плеврит, отит, остеомиелит (острый и хронический), гнойный артрит, послеоперационные гнойные осложнения, раневая инфекция, инфекции кожи и мягких тканей (пиодермия, фурункулез, флегмона, рожа)."},{"name":"Противопоказания","value":"Повышенная чувствительность к линкомицину; повышенная чувствительность к другим компонентам препарата, к клиндамицину; тяжелая печеночная и/или почечная недостаточность; беременность (за исключением случаев, когда это необходимо по \"жизненным\" показаниям), период грудного вскармливания, новорожденные (до 1 мес.)."},{"name":"Состав","value":"Действующее вещество: линкомицина гидрохлорида моногидрат (в пересчете на линкомицин) - 300,0 мг.\u003Cbr\u003EВспомогательные вещества: динатрия эдетат (этилендиаминтетрауксусной кислоты динатриевая соль) - 0,1 мг, 0,1 М раствор натрия гидроксида - до pH 6,0 мг, вода для инъекций - до 1 мл.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Линкомицин"},{"name":"Способ применения и дозы","value":"Внутривенно, внутримышечно.\u003Cbr\u003EСуточная доза для взрослых при парентеральном введении составляет 1,8 г, разовая - 0,6 г. При тяжелом течении инфекции суточная доза может быть увеличена до 2,4 г. Препарат вводят 3 раза в сутки с интервалами 8 часов.\u003Cbr\u003EДетям старше 1 месяца назначают внутривенно в суточной дозе 10-20 мг/кг, вне зависимости от возраста.\u003Cbr\u003EВнутривенно - только капельно, со скоростью 60-80 капель в минуту. Перед введением 2 мл препарата (0,6 г) разбавляют 250 мл раствора натрия хлорида 0,9%. Продолжительность лечения в зависимости от формы и тяжести заболевания составляет 7-14 дней (при остеомиелите - 3 недели и более).\u003Cbr\u003EПри длительных или повторных курсах лечение следует проводить под контролем функции печени и почек.\u003Cbr\u003EПациентам с почечно-печеночной недостаточностью линкомицин назначают парентерально в суточной дозе, не превышающей 1,8 г, с интервалами между введениями не менее 12 часов.\u003Cbr\u003E"},{"name":"Побочные действия","value":"Нарушения со стороны крови и лимфатической системы: обратимые лейкопения, тромбоцитопеническая пурпура, нейтропения, агранулоцитоз, апластическая анемия и панцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: зуд, крапивница, сыпь, эксфолиативный дерматит, везикуло-буллезный дерматит, ангионевротический отек, анафилактический шок, мультиформная эритема (синдром Стивенса-Джонсона), сывороточная болезнь.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: шум в ушах, вертиго. Нарушения со стороны желудочно-кишечного тракта: тошнота, рвота, антибиотикассоциированная диарея, боль в животе, зуд ануса, глоссит, стоматит, при длительном применении - кандидоз желудочно- кишечного тракта, псевдомембранозный колит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: желтуха, транзиторная гипербилирубинемия, повышение активности \"печеночных\" трансаминаз.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: нарушение функции почек (азотемия, олигурия, протеинурия).\u003Cbr\u003EНарушения со стороны половых органов и молочной железы: вагинит.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: при внутривенном введении - тромбофлебит, при внутримышечном введении - местное раздражение, болезненность, образование уплотнения и стерильного абсцесса в месте инъекции.\u003Cbr\u003EПри быстром внутривенном введении - снижение артериального давления, головокружение, головная боль, сонливость, общая слабость, расслабление скелетной мускулатуры, остановка дыхания и сердца.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Антибиотик, продуцируемый Streptomyces lincolnensis, оказывает бактериостатическое действие. Подавляет белковый синтез бактерий вследствие обратимого связывания с 50S субъединицей рибосом, нарушает образование пептидных связей.\u003Cbr\u003EЧувствительны in vivo: Staphylococcus aureus (пенициллиназопродуцирующие и непродуцирующие штаммы), Staphylococcus epidermidis, Streptococcus pneumoniae.\u003Cbr\u003EЧувствительны in vitro: аэробные грамположительные микроорганизмы - Streptococcus pyogenes, Streptococcus spp. группы viridans, Corynebacterium diphtheriae; анаэробные грамположительные микроорганизмы - Propionibacterium acnes, Clostridium tetani, Clostridium perfringens.\u003Cbr\u003EЭффективен в отношении Staphylococcus spp., устойчивых к пенициллину, тетрациклину, хлорамфениколу, стрептомицину, цефалоспоринам (30% Staphylococcus spp.,устойчивых к эритромицину, имеют перекрестную устойчивость к линкомицину).\u003Cbr\u003EНе действует на Enterococcus spp. (в т.ч. Enterococcus faecalis); Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae и др. грамотрицательные бактерии, а также грибы, вирусы, простейшие.\u003Cbr\u003EОптимум действия находится в щелочной среде (pH 8-8,5). Устойчивость к линкомицину развивается медленно. В высоких дозах обладает бактерицидным эффектом.\u003Cbr\u003EСуществует перекрестная резистентность между линкомицином и клиндамицином.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"антибиотики"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный"},{"name":"Минимальный возраст применения","value":"от 3 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте при температуре от 5 до 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте.\u003Cbr\u003E"},{"name":"Передозировка","value":"Симптомы: усиление выраженности проявлений дозозависимых нежелательных реакций.\u003Cbr\u003EЛечение: симптоматическая терапия, плохо удаляется при гемо- и перитонеальном диализе.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано применять во время беременности (за исключением случаев, когда это необходимо по \"жизненным\" показаниям) и в период грудного вскармливания (на время лечения грудное вскармливание необходимо прекратить)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При применении линкомицина нельзя исключить вероятность появления головокружения и расслабления скелетной мускулатуры, поэтому вождение автотранспорта и другие виды деятельности, требующие повышенного внимания и скорости реакции, не рекомендуются."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EГрибковые заболевания кожи, слизистой оболочки полости рта, влагалища; миастения; одновременное применение с лекарственными препаратами, блокирующими нервно-мышечную проводимость; сахарный диабет; печеночная/почечная недостаточность средней степени тяжести; заболевания желудочно-кишечного тракта, особенно колиты, в анамнезе.\u003Cbr\u003EПри применении линкомицина следует учитывать официальные национальные рекомендации по надлежащему применению антибактериальных препаратов, а также чувствительность патогенных микроорганизмов в конкретной стране.\u003Cbr\u003EЛинкомицин следует назначать с осторожностью пациентам с заболеваниями желудочно-кишечного тракта, особенно колитами, в анамнезе.\u003Cbr\u003EСообщалось о случаях псевдомембранозного колита, развившегося спустя 2 месяца после приема антибактериальных препаратов, которые требуют назначения ионообменных смол (колестирамин), в тяжелых случаях показано возмещение потери жидкости, электролитов и белка, ванкомицин - внутрь, в суточной дозе 0,5-2 г (за 3-4 приема) в течение 10 дней или бацитрацин. Противопоказано применение препаратов, тормозящих перистальтику кишечника.\u003Cbr\u003EЛинкомицин не показан для терапии менингита, поскольку его концентрация в спинномозговой жидкости недостаточна для лечения менингита.\u003Cbr\u003EНе рекомендуется применять линкомицин у пациентов с сахарным диабетом за исключением случаев отсутствия альтернативного лечения, поскольку отсутствуют адекватные данные о терапии пациентов с эндокринными или метаболическими заболеваниями.\u003Cbr\u003EПериод полувыведения линкомицина может быть увеличен у пациентов с нарушениями функции печени и почек, поэтому следует соблюдать осторожность при назначении линкомицина пациентам с печеночной/почечной недостаточностью средней степени тяжести и контролировать концентрацию линкомицина в крови во время терапии высокими дозами линкомицина. У таких пациентов следует рассмотреть возможность уменьшения частоты введения препарата.\u003Cbr\u003EПрименение при тяжелой печеночной/почечной недостаточности противопоказано.\u003Cbr\u003EКак и при применении других противомикробных препаратов при применении линкомицина, особенно длительном, возможно развитие вторичной инфекции, связанной с ростом устойчивых к препарату микроорганизмов (особенно грибов), для исключения и подтверждения которой, следует проводить повторную оценку состояния пациента. Если во время терапии возникает вторичная инфекция, следует принять необходимые меры по ее лечению.\u003Cbr\u003EЛинкомицин следует применять с осторожностью у пациентов с имеющимися грибковыми заболеваниями, таким пациентам следует также назначать противогрибковую терапию.\u003Cbr\u003EПри применении линкомицина сообщалось о развитии тяжелых буллезных реакций, таких как синдром Стивенса-Джонсона. Пациентов следует информировать о том, что при развитии кожных реакций и/или поражений слизистых оболочек, необходимо немедленно проконсультироваться у врача прежде, чем продолжать лечение линкомицином.\u003Cbr\u003EПри применении линкомицина сообщалось о развитии аллергических реакций, которые могут прогрессировать до жизнеугрожающего состояния. В этих случаях следует прекратить применение линкомицина и начать проведение соответствующего лечения.\u003Cbr\u003EЛинкомицин характеризуется блокирующей нервно-мышечное проведение активностью и может усиливать мышечную слабость у пациентов с псевдопаралитической миастенией. Применение линкомицина у пациентов с установленным диагнозом псевдопаралитической миастении не рекомендуется.\u003Cbr\u003EСообщалось о случаях развития нейтропении и/или лейкопении на фоне лечения линкомицином, поэтому во время терапии рекомендуется периодический контроль анализа крови.\u003Cbr\u003EНа фоне длительного лечения необходим периодический контроль активности \"печеночных\" трансаминаз и функции почек. При выявлении нарушений следует рассмотреть возможность отмены препарата.\u003Cbr\u003EВо избежание развития асептического некроза вводить лучше глубоко внутримышечно. Внутривенно вводить без предварительного разведения нельзя.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Фармацевтически несовместим с канамицином, ампициллином, барбитуратами, теофиллином, кальция глюконатом, гепарином и магния сульфатом.\u003Cbr\u003EАнтагонизм - с эритромицином, пенициллинами, цефалоспоринами и хлорамфениколом, ампициллином и другими бактерицидными антибиотиками, синергизм - с аминогликозидами.\u003Cbr\u003EУсиливает действие лекарственных средств для ингаляционного наркоза, миорелаксантов и опиоидных анальгетиков, повышая риск нервно-мышечной блокады и остановки дыхания.\u003Cbr\u003EПри одновременном применении теофиллина с линкомицином, ингибиторами изоферментов цитохрома Р450, эффективность теофиллина может увеличиваться, что может потребовать снижения его дозы.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"P N001864/01-2002"},{"name":"Дата государственной регистрации","value":"23.04.2018"},{"name":"Владелец регистрационного удостоверения","value":"Дальхимфарм"},{"name":"Изготовитель","value":"Дальхимфарм"},{"name":"Фасовщик","value":"Дальхимфарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Линкомицин"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_16129240485452575270"}}}}
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Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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147 ₽

Скидка: 25%
–25 %
Вместо:197 ₽
  • 11-13 июня, самовывоз • 0 ₽
POLZAru
Рейтинг 4.9 из 5
38Котзывов
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    на основе 8 оценок
    Цена 354 ₽
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  • Линкомицин капс., 250 мг, 20 шт.
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    Линкомицин капс., 250 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 167 ₽
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  • Гентамицин р-р для в/в введ. и в/м введ. амп., 40 мг/мл, 2 мл, 10 шт.
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    Гентамицин р-р для в/в введ. и в/м введ. амп., 40 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 12 оценок
    Цена 81 ₽
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  • Линкомицин капс., 250 мг, 20 шт.
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    Линкомицин капс., 250 мг, 20 шт.

    Рейтинг товара: 4.3 из 5
    на основе 6 оценок
    Цена 117 ₽
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  • Бициллин-3 пор. д/приг. сусп. для в/м введ., 1200000 ЕД, 1 шт.
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    Бициллин-3 пор. д/приг. сусп. для в/м введ., 1200000 ЕД, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 6 оценок
    Цена 224 ₽
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  • Левомицетин таб., 500 мг, 20 шт.
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    Левомицетин таб., 500 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 12 оценок
    Цена 151 ₽
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  • Бициллин-5 пор. д/приг. сусп. для в/м введ., 1200000 ЕД+300000 ЕД, 1 шт.
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    Бициллин-5 пор. д/приг. сусп. для в/м введ., 1200000 ЕД+300000 ЕД, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 9 оценок
    Цена 250 ₽
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  • ЛинкоВел р-р д/инф и в/м введ., 300 мг/мл, 1 мл, 10 шт.
    –35 %
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    ЛинкоВел р-р д/инф и в/м введ., 300 мг/мл, 1 мл, 10 шт.

    Цена 94 ₽ вместо 144
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  • Цефепим пор. д/приг. р-ра для в/в и в/м введ., 1 г, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-krrknuk2xi/toggleWishlist":{"skuId":"926433004","productId":1434054523,"offerId":"GYP4ZBSDSEl1Bs-Euk507A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ+OGZ1oCkofJzEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI+97nqwUQ7P3guQMY+5aQByD33MEH","sign":"0Y4WGFK8mnXudkAzD3TuNfyFciHULze0Eksulji/MQc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-krrknuk2xi/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Цефепим пор. д/приг. р-ра для в/в и в/м введ., 1 г, 1 шт.

    Рейтинг товара: 4.2 из 5
    на основе 10 оценок
    Цена 189 ₽
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  • Клиндамицин р-р д/ин., 150 мг/мл, 2 мл, 10 шт.
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    Клиндамицин р-р д/ин., 150 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 713 ₽
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  • Ципролет таб. п/о плен., 500 мг, 10 шт.
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    Ципролет таб. п/о плен., 500 мг, 10 шт.

    Рейтинг товара: 4.9 из 5
    на основе 13 оценок
    Цена 113 ₽
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Инструкция

Показания к применению

Бактериальные инфекции, вызванные чувствительными к линкомицину микроорганизмами (прежде всего Staphylococcus spp. и Streptococcus spp., особенно микроорганизмами, устойчивыми к пенициллинам, а также при аллергии к пенициллинам): сепсис, подострый септический эндокардит, абсцесс легкого, эмпиема плевры, плеврит, отит, остеомиелит (острый и хронический), гнойный артрит, послеоперационные гнойные осложнения, раневая инфекция, инфекции кожи и мягких тканей (пиодермия, фурункулез, флегмона, рожа).

Противопоказания

Повышенная чувствительность к линкомицину; повышенная чувствительность к другим компонентам препарата, к клиндамицину; тяжелая печеночная и/или почечная недостаточность; беременность (за исключением случаев, когда это необходимо по "жизненным" показаниям), период грудного вскармливания, новорожденные (до 1 мес.).

Способ применения и дозы

Внутривенно, внутримышечно.
Суточная доза для взрослых при парентеральном введении составляет 1,8 г, разовая - 0,6 г. При тяжелом течении инфекции суточная доза может быть увеличена до 2,4 г. Препарат вводят 3 раза в сутки с интервалами 8 часов.
Детям старше 1 месяца назначают внутривенно в суточной дозе 10-20 мг/кг, вне зависимости от возраста.
Внутривенно - только капельно, со скоростью 60-80 капель в минуту. Перед введением 2 мл препарата (0,6 г) разбавляют 250 мл раствора натрия хлорида 0,9%. Продолжительность лечения в зависимости от формы и тяжести заболевания составляет 7-14 дней (при остеомиелите - 3 недели и более).
При длительных или повторных курсах лечение следует проводить под контролем функции печени и почек.
Пациентам с почечно-печеночной недостаточностью линкомицин назначают парентерально в суточной дозе, не превышающей 1,8 г, с интервалами между введениями не менее 12 часов.
Полная инструкция
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Линкомицин г/хл р-р д/ин.
Линкомицин г/хл р-р д/ин., 300 мг/мл, 1 мл, 10 шт.
5.0
(1)
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1 вопрос
Инструкция

147 ₽

Скидка: 25%
–25 %
Вместо:197 ₽
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5.0
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У продавца:1 оценка·1 отзыв
У всех продавцов:18 оценок·8 отзывов
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Неделю назад • Маргарита С. • Куплен на Маркете
Достоинства: Очень удобно.
Недостатки: Недостатков нет
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