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Зиртек капли д/вн. приема, 10 мг/мл, 20 мл

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Коротко о товаре

Артикул Маркета
3123938852
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 месяцев
Инструкция
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тошнота, боли в животе, диарея, нарушение функции печени (повышение уровня трансаминаз, ЩФ, ГГТ, билирубина).\u003Cbr\u003EСо стороны мочевыделительной системы: расстройство мочеиспускания, энурез.\u003Cbr\u003EАллергические реакции: зуд, сыпь, крапивница, ангионевротический отек, повышенная чувствительность, вплоть до развития анафилактического шока.\u003Cbr\u003EСо стороны обмена веществ: увеличение массы тела.\u003Cbr\u003EПрочие: усталость, астения, недомогание, отек.\u003Cbr\u003EПобочные эффекты развиваются в очень редких случаях."},{"name":"Фармакологическое действие","value":"Цетиризин - активное вещество препарата Зиртек - является метаболитом гидроксизина, относится к группе конкурентных антагонистов гистамина и блокирует H1-гистаминовые рецепторы.\u003Cbr\u003EВ дополнение к антигистаминному эффекту цетиризин предупреждает развитие и облегчает течение аллергических реакций: в дозе 10 мг один или два раза в день ингибирует позднюю фазу агрегации эозинофилов в коже и 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Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы, наблюдаемые после явной передозировки препараты, влияли на центральную нервную систему или были связаны с возможным антихолинергическим эффектом. Симптомы, которые наблюдались после приема по меньшей мере пятикратного количества рекомендуемой суточной дозы, включали следующее: спутанность сознания, диарея, утомляемость, головная боль, недомогание, мидриаз, зуд, беспокойство, седативный эффект, сонливость, ступор, тахикардия, тремор, задержка мочи.\u003Cbr\u003EЛечение:\u003Cbr\u003EСпецифического антидота нет.\u003Cbr\u003EВ случае передозировки рекомендуется симптоматическое или поддерживающее лечение. Промывание желудка и/или приём активированного угля может быть эффективным, если передозировка произошла недавно. Цетиризин частично выводится при диализе.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Данные по применению цетиризина во время беременности ограничены (300-1000 исходов беременности). Однако не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью.\u003Cbr\u003EЭкспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и постнатальное развитие.\u003Cbr\u003EПри беременности назначение цетиризина возможно после консультации с врачом, в случае если предполагаемая польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EНе следует применять цетиризин во время грудного вскармливания, т.к. цетиризин экскретируется с грудным молоком. Цетиризин выделяется в грудное молоко в количестве 25-90 % от концентрации в плазме крови, в зависимости от времени отбора проб после приема препарата.\u003Cbr\u003EНежелательные реакции, связанные с цетиризином, могут наблюдаться у грудных детей.\u003Cbr\u003EВ период грудного вскармливания применяют после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для ребенка.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии на фертильность человека ограничены, однако отрицательного влияния на фертильность в исследованиях на животных не выявлено.\u003Cbr\u003EПеред применением препарата, если Вы беременны, или предполагаете, что Вы могли бы быть беременной, или планируете беременность, необходимо проконсультироваться с врачом.\u003Cbr\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При объективной оценке способности к вождению автотранспорта и управлению механизмами достоверно не выявлено каких-либо нежелательных явлений при приеме препарата в рекомендуемой дозе. Однако пациентам с проявлениями сонливости на фоне приема препарата целесообразно воздерживаться от управления автомобилем, занятий потенциально опасными видами деятельности или управлением механизмами, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Ввиду потенциального угнетающего влияния на центральную нервную систему следует соблюдать осторожность при назначении препарата Зиртек детям в возрасте от 6 мес до 1 года при наличии следующих факторов риска возникновения синдрома внезапной детской смерти, таких, как (но не ограничиваясь этим списком):\u003Cbr\u003E- синдром апноэ во сне или синдром внезапной детской смерти детей грудного возраста у брата или сестры;\u003Cbr\u003E- злоупотребление матери наркотиками или курением во время беременности;\u003Cbr\u003E- молодой возраст матери (19 лет и моложе);\u003Cbr\u003E- злоупотребление курением няни, ухаживающей за ребенком (одна пачка сигарет в день или более);\u003Cbr\u003E- дети, регулярно засыпающие лицом вниз и которых не укладывают на спину;\u003Cbr\u003E- недоношенные (гестационный возраст менее 37 недель) или рожденные с недостаточной массой тела (ниже 10-го перцентиля от гестационного возраста) дети;\u003Cbr\u003E- при совместном приеме препаратов, оказывающих угнетающее влияние на центральную нервную систему.\u003Cbr\u003EВ состав препарата входят вспомогательные вещества метилпарабензол и пропилпарабензол, которые могут вызвать аллергические реакции, в том числе замедленного типа.\u003Cbr\u003EУ пациентов с повреждением спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов к задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи.\u003Cbr\u003EУ пациентов с почечной недостаточностью режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EИз-за возможного снижения функции почек у пациентов пожилого возраста режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EРекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем, так как цетиризин может привести к повышенной сонливости.\u003Cbr\u003EОсторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что блокаторы H1-гистаминовых рецепторов ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EВнимательно прочтите инструкцию перед тем, как начать применение препарата. Сохраните инструкцию, она может понадобиться вновь. Если у Вас возникли вопросы, обратитесь к врачу. Лекарственное средство, которым Вы лечитесь предназначено лично Вам, и его не следует передавать другим лицам, поскольку оно может причинить им вред даже при наличии тех же симптомов, что и у Вас.\u003Cbr\u003E- Хроническая почечная недостаточность (при клиренсе креатинина \u003E 10 мл в мин требуется коррекция режима дозирования);\u003Cbr\u003E- пациенты пожилого возраста (при возрастном снижении клубочковой фильтрации);\u003Cbr\u003E- эпилепсия и пациенты с повышенной судорожной готовностью;\u003Cbr\u003E- пациенты с предрасполагающими факторами к задержке мочи;\u003Cbr\u003E- детский возраст до 1 года;\u003Cbr\u003E- при одновременном употреблении с алкоголем;\u003Cbr\u003E- период грудного вскармливания;\u003Cbr\u003E- беременность.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Одновременное применение с азитромицином, циметидином, эритромицином, кетоконазолом или псевдоэфедрином не влияет на фармакокинетические параметры цетиризина. Фармакокинетических взаимодействий не наблюдалось. Согласно испытаниям in vitro, цетиризин не влияет на эффект связывания белка варфарина.\u003Cbr\u003EОдновременный прием азитромицина, эритромицина, кетоконазола, теофиллина и псевдоэфедрина не выявил существенных изменений в клинических лабораторных показателях, жизненно важных функциях и ЭКГ.\u003Cbr\u003EВ исследовании с одновременным приемом теофиллина (400 мг в день) и цетиризина (20 мг в день) было обнаружено незначительное, но статистически достоверное повышение 24-часовой AUC (площади под кривой) на 19% для цетиризина и на 11% для теофиллина. Кроме того, максимальные уровни в плазме крови увеличились до 7,7% и 6,4% соответственно для цетиризина и теофиллина. Одновременно клиренс цетиризина уменьшился на -16%, а также на - 10% в случае теофиллина, когда цетиризин принимали пациенты, которые ранее получали лечение теофиллином. Тем не менее, предварительное лечение цетиризином не оказало существенного влияния на фармакокинетические параметры теофиллина.\u003Cbr\u003EПосле однократного приема цетиризина в дозе 10 мг эффект алкоголя (0,8%о) значительно не усиливался; статистически значимое взаимодействие с 5 мг диазепама было доказано в одном из 16 психометрических тестов.\u003Cbr\u003EОдновременный прием 10 мг цетиризина в день с глипизидом привел к незначительному снижению показателей глюкозы. Этот эффект не имеет клинического значения. Тем не менее, рекомендуется раздельный прием - глипизид утром и цетиризин вечером.\u003Cbr\u003EСтепень всасывания цетиризина не снижается при одновременном приеме пищи, хотя всасывание замедляется на 1 час,\u003Cbr\u003EВ исследовании с многократным приемом ритонавира (600 мг два раза в день) и цетиризина (10 мг в день) степень экспозиции цетиризина была увеличена примерно на 40%, в то время как, экспозиция ритонавира незначительно изменилась (-11%) вследствие сопутствующего приема цетиризина.\u003Cbr\u003EЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Зиртек проконсультируйтесь с врачом.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"П N011930/01"},{"name":"Дата государственной регистрации","value":"10.03.2020"},{"name":"Владелец регистрационного удостоверения","value":"UCB Farchim S.A.","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34324371:35649313","7893318:16228924"]}}},{"name":"Изготовитель","value":"Aesica"},{"name":"Фасовщик","value":"Aesica"},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Зиртек","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["17796364:17877894"]}}},{"name":"Срок годности","value":"59 мес."}]}},"fullSpecsGrouped":{"18211768927129574842":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"глаза, дыхательная система, иммунная система, носовая полость"},{"name":"Назначение","value":"аллергический конъюнктивит, аллергический ринит, крапивница"},{"name":"Показания к применению","value":"Применение препарата показано у взрослых и детей с 6 месяцев для облегчения: назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы; симптомов хронической идиопатической крапивницы.\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!\u003Cbr\u003E"},{"name":"Противопоказания","value":"- Повышенная чувствительность к цетиризину, гидроксизину или любым производным пиперазина, а также другим компонентам препарата;\u003Cbr\u003E- терминальная стадия почечной недостаточности (клиренс креатинина \u003C 10 мл/мин);\u003Cbr\u003E- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности применения препарата Зиртек."},{"name":"Состав","value":"Активное вещество: цетиризина дигидрохлорид 10 мг/мл.\u003Cbr\u003EВспомогательные вещества: глицерол 250,00 мг, пропиленгликоль 350,00 мг, сахаринат натрия 10,00 мг, метилпарабензол 1,35 мг, пропилпарабензол 0,15 мг, ацетат натрия 10,00 мг, ледяная уксусная кислота 0,53 мг, вода очищенная до 1,00 мл."},{"name":"Действующее вещество","value":"Цетиризин"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПринимать препарат следует вечером, т.к. симптомы становятся более выраженными вечером.\u003Cbr\u003EПри необходимости препарат Зиртек можно запить стаканом воды.\u003Cbr\u003EПрепарат Зиртек® можно принимать независимо от приёма пищи.\u003Cbr\u003EВзрослым\u003Cbr\u003E10 мг (20 капель) 1 раз в день.\u003Cbr\u003EАльтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).\u003Cbr\u003EДети\u003Cbr\u003EПрименение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!\u003Cbr\u003EДети от 6 до 12 месяцев\u003Cbr\u003E2,5 мг (5 капель) 1 раз в день.\u003Cbr\u003EДети от 1 года до 6 лет\u003Cbr\u003E2,5 мг (5 капель) 2 раза в день утром и вечером\u003Cbr\u003EПродолжительность лечения не должна превышать 4 недель.\u003Cbr\u003EДети от 6 до 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день\u003Cbr\u003EПродолжительность лечения не должна превышать 4 недель.\u003Cbr\u003EАльтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).\u003Cbr\u003EДети старше 12 лет\u003Cbr\u003E10 мг (20 капель) 1 раз в день\u003Cbr\u003EИногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.\u003Cbr\u003EДетям с почечной недостаточностью дозу корректируют с учетом КК и массы тела.\u003Cbr\u003EОтдельные группы пациентов\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EИз-за возможного снижения функции почек режим дозирования препарата следует корректировать (см. подраздел \"Пациенты с почечной недостаточностью\" раздела \"Способ применения и дозы\".\u003Cbr\u003EПациенты с почечной недостаточностью\u003Cbr\u003EПоскольку препарат Зиртек выводится из организма в основном почками, при невозможности альтернативного лечения пациентов с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины клиренса креатинина - КК).\u003Cbr\u003EКК для мужчин можно рассчитать, исходя из концентрации сывороточного креатинина, по следующей формуле:\u003Cbr\u003EКК(мл/мин)= [140 - возраст (годы)] х масса тела (кг) / 72 х ККсыворот (мг/дл)\u003Cbr\u003EКК для женщин можно рассчитать, умножив полученное значение на коэффициент 0,85.\u003Cbr\u003EУ пациентов с нарушением только функции печени коррекции режима дозирования не требуется.\u003Cbr\u003E Если после лечения улучшения не наступает или появляются новые симптомы, необходимо проконсультироваться с врачом.\u003Cbr\u003EПрименяйте препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции.\u003Cbr\u003E"},{"name":"Побочные действия","value":"Со стороны системы кроветворения: тромбоцитопения.\u003Cbr\u003EСо стороны нервной системы: сонливость, головокружение, головная боль, агрессия, возбуждение, замешательство, депрессия, галлюцинации, бессонница, тик, судороги, дискинезия, дистония, парестезия, обморок, тремор.\u003Cbr\u003EСо стороны органа зрения: нарушение аккомодации, нечеткое зрение, нистагм.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: тахикардия.\u003Cbr\u003EСо стороны дыхательной системы: ринит, фарингит.\u003Cbr\u003EСо стороны пищеварительной системы: сухость во рту, тошнота, боли в животе, диарея, нарушение функции печени (повышение уровня трансаминаз, ЩФ, ГГТ, билирубина).\u003Cbr\u003EСо стороны мочевыделительной системы: расстройство мочеиспускания, энурез.\u003Cbr\u003EАллергические реакции: зуд, сыпь, крапивница, ангионевротический отек, повышенная чувствительность, вплоть до развития анафилактического шока.\u003Cbr\u003EСо стороны обмена веществ: увеличение массы тела.\u003Cbr\u003EПрочие: усталость, астения, недомогание, отек.\u003Cbr\u003EПобочные эффекты развиваются в очень редких случаях."},{"name":"Фармакологическое действие","value":"Цетиризин - активное вещество препарата Зиртек - является метаболитом гидроксизина, относится к группе конкурентных антагонистов гистамина и блокирует H1-гистаминовые рецепторы.\u003Cbr\u003EВ дополнение к антигистаминному эффекту цетиризин предупреждает развитие и облегчает течение аллергических реакций: в дозе 10 мг один или два раза в день ингибирует позднюю фазу агрегации эозинофилов в коже и конъюнктиве пациентов, подверженных атопии."},{"name":"Фармакологическая группа","value":"противоаллергическое средство - H1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"капли для приема внутрь"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 6 месяцев"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы, наблюдаемые после явной передозировки препараты, влияли на центральную нервную систему или были связаны с возможным антихолинергическим эффектом. Симптомы, которые наблюдались после приема по меньшей мере пятикратного количества рекомендуемой суточной дозы, включали следующее: спутанность сознания, диарея, утомляемость, головная боль, недомогание, мидриаз, зуд, беспокойство, седативный эффект, сонливость, ступор, тахикардия, тремор, задержка мочи.\u003Cbr\u003EЛечение:\u003Cbr\u003EСпецифического антидота нет.\u003Cbr\u003EВ случае передозировки рекомендуется симптоматическое или поддерживающее лечение. Промывание желудка и/или приём активированного угля может быть эффективным, если передозировка произошла недавно. Цетиризин частично выводится при диализе.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Данные по применению цетиризина во время беременности ограничены (300-1000 исходов беременности). Однако не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью.\u003Cbr\u003EЭкспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и постнатальное развитие.\u003Cbr\u003EПри беременности назначение цетиризина возможно после консультации с врачом, в случае если предполагаемая польза для матери превышает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EНе следует применять цетиризин во время грудного вскармливания, т.к. цетиризин экскретируется с грудным молоком. Цетиризин выделяется в грудное молоко в количестве 25-90 % от концентрации в плазме крови, в зависимости от времени отбора проб после приема препарата.\u003Cbr\u003EНежелательные реакции, связанные с цетиризином, могут наблюдаться у грудных детей.\u003Cbr\u003EВ период грудного вскармливания применяют после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для ребенка.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии на фертильность человека ограничены, однако отрицательного влияния на фертильность в исследованиях на животных не выявлено.\u003Cbr\u003EПеред применением препарата, если Вы беременны, или предполагаете, что Вы могли бы быть беременной, или планируете беременность, необходимо проконсультироваться с врачом.\u003Cbr\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При объективной оценке способности к вождению автотранспорта и управлению механизмами достоверно не выявлено каких-либо нежелательных явлений при приеме препарата в рекомендуемой дозе. Однако пациентам с проявлениями сонливости на фоне приема препарата целесообразно воздерживаться от управления автомобилем, занятий потенциально опасными видами деятельности или управлением механизмами, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Ввиду потенциального угнетающего влияния на центральную нервную систему следует соблюдать осторожность при назначении препарата Зиртек детям в возрасте от 6 мес до 1 года при наличии следующих факторов риска возникновения синдрома внезапной детской смерти, таких, как (но не ограничиваясь этим списком):\u003Cbr\u003E- синдром апноэ во сне или синдром внезапной детской смерти детей грудного возраста у брата или сестры;\u003Cbr\u003E- злоупотребление матери наркотиками или курением во время беременности;\u003Cbr\u003E- молодой возраст матери (19 лет и моложе);\u003Cbr\u003E- злоупотребление курением няни, ухаживающей за ребенком (одна пачка сигарет в день или более);\u003Cbr\u003E- дети, регулярно засыпающие лицом вниз и которых не укладывают на спину;\u003Cbr\u003E- недоношенные (гестационный возраст менее 37 недель) или рожденные с недостаточной массой тела (ниже 10-го перцентиля от гестационного возраста) дети;\u003Cbr\u003E- при совместном приеме препаратов, оказывающих угнетающее влияние на центральную нервную систему.\u003Cbr\u003EВ состав препарата входят вспомогательные вещества метилпарабензол и пропилпарабензол, которые могут вызвать аллергические реакции, в том числе замедленного типа.\u003Cbr\u003EУ пациентов с повреждением спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов к задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи.\u003Cbr\u003EУ пациентов с почечной недостаточностью режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EИз-за возможного снижения функции почек у пациентов пожилого возраста режим дозирования препарата следует корректировать (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EРекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем, так как цетиризин может привести к повышенной сонливости.\u003Cbr\u003EОсторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что блокаторы H1-гистаминовых рецепторов ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EВнимательно прочтите инструкцию перед тем, как начать применение препарата. Сохраните инструкцию, она может понадобиться вновь. Если у Вас возникли вопросы, обратитесь к врачу. Лекарственное средство, которым Вы лечитесь предназначено лично Вам, и его не следует передавать другим лицам, поскольку оно может причинить им вред даже при наличии тех же симптомов, что и у Вас.\u003Cbr\u003E- Хроническая почечная недостаточность (при клиренсе креатинина \u003E 10 мл в мин требуется коррекция режима дозирования);\u003Cbr\u003E- пациенты пожилого возраста (при возрастном снижении клубочковой фильтрации);\u003Cbr\u003E- эпилепсия и пациенты с повышенной судорожной готовностью;\u003Cbr\u003E- пациенты с предрасполагающими факторами к задержке мочи;\u003Cbr\u003E- детский возраст до 1 года;\u003Cbr\u003E- при одновременном употреблении с алкоголем;\u003Cbr\u003E- период грудного вскармливания;\u003Cbr\u003E- беременность.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Одновременное применение с азитромицином, циметидином, эритромицином, кетоконазолом или псевдоэфедрином не влияет на фармакокинетические параметры цетиризина. Фармакокинетических взаимодействий не наблюдалось. Согласно испытаниям in vitro, цетиризин не влияет на эффект связывания белка варфарина.\u003Cbr\u003EОдновременный прием азитромицина, эритромицина, кетоконазола, теофиллина и псевдоэфедрина не выявил существенных изменений в клинических лабораторных показателях, жизненно важных функциях и ЭКГ.\u003Cbr\u003EВ исследовании с одновременным приемом теофиллина (400 мг в день) и цетиризина (20 мг в день) было обнаружено незначительное, но статистически достоверное повышение 24-часовой AUC (площади под кривой) на 19% для цетиризина и на 11% для теофиллина. Кроме того, максимальные уровни в плазме крови увеличились до 7,7% и 6,4% соответственно для цетиризина и теофиллина. Одновременно клиренс цетиризина уменьшился на -16%, а также на - 10% в случае теофиллина, когда цетиризин принимали пациенты, которые ранее получали лечение теофиллином. Тем не менее, предварительное лечение цетиризином не оказало существенного влияния на фармакокинетические параметры теофиллина.\u003Cbr\u003EПосле однократного приема цетиризина в дозе 10 мг эффект алкоголя (0,8%о) значительно не усиливался; статистически значимое взаимодействие с 5 мг диазепама было доказано в одном из 16 психометрических тестов.\u003Cbr\u003EОдновременный прием 10 мг цетиризина в день с глипизидом привел к незначительному снижению показателей глюкозы. Этот эффект не имеет клинического значения. Тем не менее, рекомендуется раздельный прием - глипизид утром и цетиризин вечером.\u003Cbr\u003EСтепень всасывания цетиризина не снижается при одновременном приеме пищи, хотя всасывание замедляется на 1 час,\u003Cbr\u003EВ исследовании с многократным приемом ритонавира (600 мг два раза в день) и цетиризина (10 мг в день) степень экспозиции цетиризина была увеличена примерно на 40%, в то время как, экспозиция ритонавира незначительно изменилась (-11%) вследствие сопутствующего приема цетиризина.\u003Cbr\u003EЕсли Вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Зиртек проконсультируйтесь с врачом.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"П N011930/01"},{"name":"Дата государственной регистрации","value":"10.03.2020"},{"name":"Владелец регистрационного удостоверения","value":"UCB Farchim S.A."},{"name":"Изготовитель","value":"Aesica"},{"name":"Фасовщик","value":"Aesica"},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Зиртек"},{"name":"Срок годности","value":"59 мес."}]}],"transitionId":"tr_493700320193356349"}}}}
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Цена с картой Яндекс Пэй:212 ₽

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Вместо: 214 ₽248 ₽
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  • Цетрин таб. п/о плен., 10 мг, 20 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-y63e4mb4qi/toggleWishlist":{"skuId":"228119468","productId":1417730432,"offerId":"9p6ApXvfgPVXnObxT41jlg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/OvQ45W53rhfEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIgLODpAUQrKfjbBjAotUHINbZwQc=","sign":"MfdXaxrMrhBptzoKatnhqXeehh+Aeqah4Oaieh/SU3w="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-y63e4mb4qi/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Цетрин таб. п/о плен., 10 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 201 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 160 ₽ вместо 162
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  • Зодак таб. п/о плен., 10 мг, 30 шт.
    –17 %
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    Зодак таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 79 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 266 ₽ вместо 269
    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  • Фенистил капли д/вн. приема, 0.1%, 20 мл
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-lepj50aheyc/toggleWishlist":{"skuId":"228204900","productId":1778170162,"offerId":"uWMG8h0rINHwsb6iBv5axw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/OvQ45W53rhfEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIsvLyzwYQ5MLobBjZ3tYFINbZwQc=","sign":"x1/MF11Zq95Juvp0hB8vS7swJvYF7ohFq/wXpqVKW+w="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-lepj50aheyc/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Фенистил капли д/вн. приема, 0.1%, 20 мл

    Рейтинг товара: 4.8 из 5
    на основе 20 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 577 ₽ вместо 583
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  • Зиртек таб. п/о плен., 10 мг, 30 шт.
    –1 %
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    Зиртек таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 22 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 291 ₽ вместо 294
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  • Зиртек таб. п/о плен. (блистер), 10 мг, 20 шт.
    –1 %
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    Зиртек таб. п/о плен. (блистер), 10 мг, 20 шт.

    Рейтинг товара: 4.6 из 5
    на основе 23 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 206 ₽ вместо 208
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  • Цетиризин капли д/вн. приема, 10 мг/мл, 10 мл
    –1 %
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    Цетиризин капли д/вн. приема, 10 мг/мл, 10 мл

    Рейтинг товара: 4.2 из 5
    на основе 10 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 105 ₽ вместо 106
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  • Супрастинекс капли д/вн. приема фл., 5 мг/мл, 20 мл
    –1 %
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    Супрастинекс капли д/вн. приема фл., 5 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 414 ₽ вместо 418
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  • Супрастин таб., 25 мг, 1 мл, 20 шт.
    –12 %
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    Супрастин таб., 25 мг, 1 мл, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 145 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 146 ₽ вместо 147
    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таб., 25 мг, 1 мл, 20 шт.","label":"v61z16hcq5","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":1538707,"key":"img_id8441917756753349298.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96WFVmZtSFtMyZQgwYujECEA4_RBXD3v21PJNtmyVuji89G4_W0YEFNE_9UzVdeatSEFi_dWlnu7qTgI12ElTh9Dix_DuIqxf9EB3NjwFE57xGeupEoz_WmN5aMe5aVXdrsoCopeIg7uUY0OFiT1TNRCvSSW86fH1JIgWZ1cgCRHesQZ5XbQs_X6alsnSTzZ4zCzr2CRl1qgMSKaTH_iue83PCMHYfNUeCXbx6H3kNHLFpLyTnsniKtk4UDThXO36-FNikc-qkCJj2HOduKGc6_kHnck_gG-hI3CBmqKAu5BrOqtuDU6U4XfwC8hdPusAFbTdhO5b54ou5pai2dJ4E4VvEJrPuouEj4docV5Ua7TBBxQJOiLSiktaWnp2MQOzmbHcNpEwbESlj1WxaJRSGGMnJB_GAbip1pqasBY4vIqnTuqm2AMbdO3_c1RBdbz-aXRBSx4T1SkbyIsFcVkUZiDUQz_5ratbuP1E5thjko0zIAWMIqb8jv2sOIQsoVyNJT9eWQCWAFmuH7D14oqdDL1Q73r5YIn4KEsdht1Feij55WuMsGzCQMGqPJyo-gypxW9PC0edyk7ZTZa02V634jE_OC--CiPkM6GH_0wPlgSVOeP-2syTy33f-seLhebanOQGm21ixo34zqEmR2Cn4N3-e-JcVVj96xNU0L7xBf4tyxy5lsdJaNpSLgcwy9VCCLiQ5uKq2wEqNRD2k8JtcqytHuctCtk7Lciv7o0zjjfe3sjHmvEA8y9e5mrVowge20NOJ_1y_f3dYqE4CKEJC2R76pW8G37GSLZ9Gc7MZFu-ZyRIJzdOhgcOT-zw9T9gY1EwfkeiNNMpwCHA6NgKjDM4UpvVGM93HoYqR36Kb8Xf07K8SxVGS4ThsmUL4TXfEk50JfvtfQ9emb2Yro-bdDRrLhxGGuUpqNwfAdHPK3omwXt0Ovw5w_zr5wMIzWRh_c_zI101L69QnaKAM3akKYKZGg_4bvEP5FkAxwYCYk0PyrUAE5INO8DrtCRkEuXyRanog2REJdQXBpsm-3nBH7AD35oESQzZIQMl6a5Pr4XvYb-LyDQtNE42AWf4j5Y-H8SiQz8iENGl4hVZYVlWQyxU-FyeTvrmprTR1VBwr8GLtBkgaUDRw8JOhlmh05dbInQ7_ZP-oGvmEZlWL4CRHuAaUHuqhEjSK7FXZ-lwUMVnGkk2jTYH9apN3z8SljMKNTTE39mZuf7uHYELKEy263pp6abCxywXFUQ2FpIlnvXBFhGQ8RlTTLsChQe1K3p3A61fxvDixscxhX8-h6gE2g3XEER3detQLOuPSihQGhueHCsKl7kMu-T3WH3Mql25o1PxSmbhhQBer2UMny0tL_DAa1H0luwWaS0LiHTX-v1V4R4J97YcWuUM-GZEKPCjO02N3F2o9xcKhO29yhnpvN4IjPEeeZROEbOU50NWyckc8CMq0yqdfDt0p8fu7eRjETCL4Y3-5oEjspudWvG16bmgdBgW1VUyHXLBl2Q8SLcnSxY93MgqFCt1GAlXP35nlNLZIPcuoXF-ejX_hA6zBrxjBabq7UuG8cy1pqxUtiU-iWtP56aTfBGCBPuOPjAeGlDSSQ0m9KY-15O-7broVOZxnWrodm_yfnZiH7AzEr_jHLB1x0ADZ5-BvyCJPzr88PUa7nGPMn0X0UTqIHRtxFT9kfYAH6Mk28DZIMHiWIR9J2yYnwfeqyHn9G86Gp_q3ABjUNycJlVJbaapRrWV7sJplx8SDsv4T6A-0gIzvQxfMyF_AFcpNS-lyp1TC9pFtTr3q4t3_XgKYIvafOi7-gnBN24qE92yxHCydyh0cVqxuloiXyZuHFm4baVheXdQ9jz1hQb21Mp1SobwpEOfrE74UW53MmMLi5EFoRofHtQrKLOVF34HAF2N8O_r4pvDXjxtgDK1Qdc6Yaey6dj_mbLaKbqJzq_ZEliWELZhqRp5rP8HJOpo0lZslLAqHUBiZD0bnh0zfzJzEr-5k2tVGvVtgTP3a1jb_IjkzVAHQN7IrQDKjfq50uswtjIPDbgXrRJFuG35DkOrcECPiE-uGJ9mmigmMJXw9tBBP6Hwc3f_HH_XTpim6VuBdfSStTnb2XYPH9N9N1sebI9uGyZa9hO3Z6ibafdBYty33DYq9xnP5b3j1l513BvB93iD1lCAtNlCu8Vm1fJHGyv-wAjar9LXLPJbM9vmX35ytRTmQp8VR3gCiYeKGKAckudCVg688MPebW1Nd28PTP6G9wwmQ7tGPvWWw67x6fcFrK1Xehs6Bq21GDxQvIjPFk2m_CJFJlw1GFRZBCaqMSlB1L7EU80alb0fJvJuXgRWBG5rLuFRHHOobLfSb-j7Y44GvfWS3UcjhQPn4vkX0TafKI8DPtFn4YWm79ICWKcCc8aFXmh2_sgbrYzIDmY2mS6Fv5xmEbwq1ksRJsMZJ1d5w9GiuVNkWzaJk5T_Y2lfAeQ5sWosrxe8PW-8olUyCwkb84NzrMrP3U0vTPrCxShwhwjkQMxYOdzuTbUeQkLTVMhd7w1jkp8Rh5lDFSEaejOaId5MpAcOKhvWSUqKlOMXZYb4lshq46Y1SBfysxuuz40BXqI-fhhDcRLxMeUNheN2N-X-nlOxrGKrjAM6c8cd8MtYf6w4P8btfn-jrWIvSHPxIyOP33d3OHl47VwSEE_JgydCgmnTp5rxcOe3MYvWzkIxGNlAkpKze5NambJzbiJ2V3UOOHKGuJ4dUf7OV0DkGrb5oNyds0XTlk5kwTw9DJV42ADowzGJLUgEXtEmQT8NqpmK1gx3nVRxcWAQ5vxyhOih6KAXxm1BkMHndOfnFVS4EYDpOo1rQbXcqWKvzJRQOsggHO53lHRblLbND5GVL8w0aCQmvtag9WLrvnmlJBNgP5IamS6rCXMcQoLJm-S8oq3MyulLnRj9jv4VMaJXH5YjrquDgUMiRvVy7uOhd5CvZZe7ESXU1pkpigfIUkX9HN_-lTvD4LmYNqFuPf-byqBiDItsQVJS9ZJCSsPhbFT75PyET9lSUVvGBn6CBlrg3Zxkl12v57KhQusZBCcBqZSuhThGzP3UNThP9YOtsdNPpb5UrMB0yDLXfC-CSI5yMoFhTmNBHhbkpgOst8hjFOLtzXWDuPuF9oRc3b5guvJJfUOqpRbG3gx8bGHTQPIfJf0j_lBkxfYX2-88KSmKZJVMMi7zNCfNAcRuFc1P3cYhXTZKUo_G4NBIq7FU_XdaLhUSgS8jJFvQ_e_Ryudjjai7yacFQDaDylN-ebFqJzr231uNVklhFC1bFt2_REiKJvPVSWMD2RF0UDQg_M66L3vNneyPExGil11Sg3PwbKu1s5wmnzIXBwCrJQ_NXEQWIxGD9dm2FAzRga7TpW-m4NtpH4,/b64e=1/sign=1933dbab1579d462a12c6599d406c5db/keyno=MARKET_1/*","showUid":"17179653095057075509606009","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/OvQ45W53rhfEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIjrODpAUQ2djQbBiS3dAHINbZwQc=","sign":"XBKqD13Ot6DHk4oXjPcbF0YksO+a+P4d8dFTmZiV8As="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/OvQ45W53rhfEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIjrODpAUQ2djQbBiS3dAHINbZwQc=","sign":"XBKqD13Ot6DHk4oXjPcbF0YksO+a+P4d8dFTmZiV8As="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8mzx6nbsxn8/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Цетиризин таб. п/о плен., 10 мг, 10 шт.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-frn0oif4phi/toggleWishlist":{"skuId":"454094049","productId":1417730416,"offerId":"BcjgIqXs2ZFBLRg_z8SNwg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/OvQ45W53rhfEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI8LKDpAUQ4dnD2AEYtNWHBCDW2cEH","sign":"HSWYtHRZ/CgiGscsiPYDpGP1+m/OhGkNEkFYkdTapdc="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-frn0oif4phi/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Цетиризин таб. п/о плен., 10 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 47 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 60 ₽ вместо 61
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  • Солонэкс капли д/вн. приема, 10 мг/мл, 20 мл
    –1 %
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    Солонэкс капли д/вн. приема, 10 мг/мл, 20 мл

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 197 ₽ вместо 199
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Инструкция

Показания к применению

Применение препарата показано у взрослых и детей с 6 месяцев для облегчения: назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы; симптомов хронической идиопатической крапивницы.
Применение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!

Противопоказания

- Повышенная чувствительность к цетиризину, гидроксизину или любым производным пиперазина, а также другим компонентам препарата;
- терминальная стадия почечной недостаточности (клиренс креатинина < 10 мл/мин);
- детский возраст до 6 месяцев (ввиду ограниченности данных по эффективности и безопасности применения препарата Зиртек.

Способ применения и дозы

Внутрь.
Принимать препарат следует вечером, т.к. симптомы становятся более выраженными вечером.
При необходимости препарат Зиртек можно запить стаканом воды.
Препарат Зиртек® можно принимать независимо от приёма пищи.
Взрослым
10 мг (20 капель) 1 раз в день.
Альтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).
Дети
Применение у детей от 6 до 12 месяцев возможно только по назначению врача и под строгим медицинским контролем!
Дети от 6 до 12 месяцев
2,5 мг (5 капель) 1 раз в день.
Дети от 1 года до 6 лет
2,5 мг (5 капель) 2 раза в день утром и вечером
Продолжительность лечения не должна превышать 4 недель.
Дети от 6 до 12 лет
10 мг (20 капель) 1 раз в день
Продолжительность лечения не должна превышать 4 недель.
Альтернативно, доза может быть разделена на два приема (по 10 капель утром и вечером).
Дети старше 12 лет
10 мг (20 капель) 1 раз в день
Иногда начальной дозы 5 мг (10 капель) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.
Детям с почечной недостаточностью дозу корректируют с учетом КК и массы тела.
Отдельные группы пациентов
Пациенты пожилого возраста
Из-за возможного снижения функции почек режим дозирования препарата следует корректировать (см. подраздел "Пациенты с почечной недостаточностью" раздела "Способ применения и дозы".
Пациенты с почечной недостаточностью
Поскольку препарат Зиртек выводится из организма в основном почками, при невозможности альтернативного лечения пациентов с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины клиренса креатинина - КК).
КК для мужчин можно рассчитать, исходя из концентрации сывороточного креатинина, по следующей формуле:
КК(мл/мин)= [140 - возраст (годы)] х масса тела (кг) / 72 х ККсыворот (мг/дл)
КК для женщин можно рассчитать, умножив полученное значение на коэффициент 0,85.
У пациентов с нарушением только функции печени коррекции режима дозирования не требуется.
Если после лечения улучшения не наступает или появляются новые симптомы, необходимо проконсультироваться с врачом.
Применяйте препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции.
Полная инструкция
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Зиртек капли д/вн. приема
Зиртек капли д/вн. приема, 10 мг/мл, 20 мл
5.0
(83)
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4 вопроса
Инструкция

Цена с картой Яндекс Пэй:212 ₽

Скидка: 15%
–15 %
Вместо: 214 ₽248 ₽
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5.0
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У продавца:83 оценки·10 отзывов
У всех продавцов:251 оценка·79 отзывов
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user avatar
3 месяца назад • Вера Р. • Куплен на Маркете
Достоинства: Состав,качество,цена,удобный флакон
Недостатки: Их нет!
Комментарий: Капли великолепно справляются с увлажнением глазок.
user avatar
3 месяца назад • Анна • Куплен на Маркете
Достоинства: Хорошие капли. Даю ребёнку при пищевой аллергии.
Недостатки: Их нет.
Комментарий: Цена ниже аптек в городе
user avatar
Год назад • Людмила Солдатова • Куплен на Маркете
Достоинства: помогает ребенку от симптомов аллергии на шерсть кошек. относительно других подобных лекарств очень приемливая цена
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