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Описание

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Левомицетин-ЛекТ таб., 500 мг, 10 шт.

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Коротко о товаре

Артикул Маркета
4683699920
Тип препарата
Назначение
Действующее вещество
Возраст
от 3 лет
Инструкция
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повидон К30 - 5,5 мг; кальция стеарат - 5,5 мг."},{"name":"Действующее вещество","value":"Хлорамфеникол","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["27144131:28710824"]}}},{"name":"Способ применения и дозы","value":"Внутрь (за 30 мин до еды, а при развитии тошноты и рвоты - через 1 ч после еды) 3-4 раза в сутки.\u003Cbr\u003EРазовая доза для взрослых 250 - 500 мг, суточная - 2000 мг.\u003Cbr\u003EДетям старше 3-х лет и с массой тела более 20 кг применяют по 12,5 мг/кг каждые 6 ч или по 25 мг/кг каждые 12 ч, (под контролем концентрации препарата в сыворотке крови).\u003Cbr\u003EСредняя продолжительность лечения - 8-10 дней."},{"name":"Побочные действия","value":"Со стороны пищеварительной системы: диспепсия, тошнота, рвота (вероятность развития снижается при приеме через 1 ч после еды), диарея, раздражение слизистой оболочки полости рта и зева, дисбактериоз (подавление нормальной микрофлоры).\u003Cbr\u003EСо стороны органов кроветворения: ретикулоцитопения, лейкопения, гранулоцитопения, тромбоцитотопения, эритроцитопения; апластическая анемия, агранулоцитоз.\u003Cbr\u003EСо стороны нервной системы: психомоторные расстройства, депрессия, спутанность сознания, периферический неврит, неврит зрительного нерва, зрительные и слуховые галлюцинации, снижение остроты зрения и слуха, головная боль.\u003Cbr\u003EАллергические реакции: кожная сыпь, ангионевротический отек.\u003Cbr\u003EПрочие: вторичная грибковая инфекция."},{"name":"Фармакологическое действие","value":"Фармакодинамика:\u003Cbr\u003EБактериостатический антибиотик широкого спектра действия, нарушает процесс синтеза белка в микробной клетке на стадии переноса аминокислот т-РНК на рибосомы.\u003Cbr\u003EЭффективен в отношении штаммов бактерий, устойчивых к пенициллину, тетрациклинам, сульфаниламидам.\u003Cbr\u003EАктивен в отношении многих грамположительных и грамотрицательных бактерий, возбудителей гнойных, кишечных инфекций, менингококковой инфекции: Escherichia coli, Shigella dysenteria, Shigella flexneri spp., Shigella boydii spp., Shigella sonnei, Salmonella spp. (в т. ч. Salmonella typhi, Salmonella paratyphi), Staphylococcus spp., Streptocjccus spp. (в т. ч. Streptocjccus pneumonia), Neisseria meningitides, Neisseria gonorrhoeae, ряда штаммов Proteus spp., Burkholderia pseudomallei, Rickettsia spp., Treponema spp., Leptospira spp., Chlamydia spp. (в т. ч. Chlamydia trachomatis), Coxiella burnetii, Ehrlicha canis, Bacteroides fragilis, Klebsiella pneumonia, Haemophilus influenza. He действует на кислотоустойчивые бактерии (в т. ч. Mycobacterium tuberculosis), анаэробы, устойчивые к метицилину штаммы стафилококков, Acinetobacter, Enterobacter, Serratia marcescent, индолположительные штаммы Proteus spp., Pseudomonas aeruginosa spp., простейшие и грибы. Устойчивость микроорганизмов развивается медленно.\u003Cbr\u003EФармакокинетика:\u003Cbr\u003EАбсорбция - 90 % (быстрая и почти полная). \u003Cbr\u003E Биодоступность - 80 % после приема внутрь и 70 % - после в/м введения. \u003Cbr\u003E Связь с белками плазмы - 50-60 %, у недоношенных новорожденных - 32 %. \u003Cbr\u003EВремя достижения максимальной концентрации (ТСmах) после перорального приема - 1-3 ч, после в/в введения -1-1,5 ч. \u003Cbr\u003EОбъем распределения - 0,6-1 л/кг.\u003Cbr\u003EТерапевтическая концентрация в крови сохраняется в течение 4-5 ч после приема.\u003Cbr\u003EХорошо проникает в жидкости и ткани организма. \u003Cbr\u003EНаибольшие его концентрации создаются в печени и почках. В желчи обнаруживается до 30 % от введенной дозы. \u003Cbr\u003EМаксимальная концентрация (Сmах) в\u003Cbr\u003Eспинномозговой жидкости (СМЖ) определяется через 4-5 ч после однократного приема внутрь и может достигать при отсутствии воспаления мозговых оболочек 21-50 % от максимальной концентрации (Сmах) в плазме и 45-89 % - при наличии воспаления мозговых оболочек. Проходит через плацентарный барьер, концентрации в сыворотке крови плода могут составлять 30-80 % от таковой в крови матери. \u003Cbr\u003E Проникает в грудное молоко.\u003Cbr\u003EОсновное количество (90 %) метаболизируется в печени. \u003Cbr\u003EВ кишечнике под влиянием кишечных бактерий гидролизуется с образованием неактивных метаболитов.\u003Cbr\u003EВыводится в течение 24 ч почками - 90 % (путем клубочковой фильтрации - 5-10 % в неизменном виде, путем канальцевой секреции в виде неактивных метаболитов - 80 %), через кишечник - 1-3 %.\u003Cbr\u003E Период полувыведения у взрослых 1,5-3,5 ч, при нарушении функции почек - 3-11 ч. \u003Cbr\u003EПериод полувыведения у детей от 3 лет до 16 лет - 3-6,5 ч. Слабо выводится в ходе гемодиализа."},{"name":"Фармакологическая группа","value":"антибиотики"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 3 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °C.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: угнетение костномозгового кроветворения, желудочно-кишечные расстройства, поражение печени и почек, нейропатия (в том числе зрительного нерва) и ретинопатия.\u003Cbr\u003EЛечение: гемосорбция, симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения необходимо соблюдать осторожность при управлении транспортными средствами и занятии другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"При одновременном приеме этанола возможно развитие дисульфирамоподобной реакции (гиперемия кожных покровов, тахикардия, тошнота, рвота, рефлекторный кашель, судороги).\u003Cbr\u003EВ процессе лечения необходим систематический контроль картины периферической крови."},{"name":"Взаимодействие","value":"Подавляет ферментную систему цитохрома Р450, поэтому при одновременном применении с фенобарбиталом, фенитоином, непрямыми антикоагулянтами отмечается ослабление метаболизма этих лекарственных средств, замедление выведения и повышение их концентрации в плазме. \u003Cbr\u003EПри одновременном применении с эритромицином, клиндамицином, линкомицином отмечается взаимное ослабление действия за счет того, что хлорамфеникол может вытеснять эти лекарственные средства из связанного состояния или препятствовать их связыванию с субъединицей 50S бактериальных рибосом.\u003Cbr\u003EОдновременное назначение с лекарственными средствами, угнетающими кроветворение (сульфаниламиды, цитостатики), влияющими на обмен веществ в печени, с лучевой терапией увеличивает риск развития побочного действия.\u003Cbr\u003EПри назначении с пероральными гипогликемическими лекарственными средствами отмечается усиление их действия (за счет подавления метаболизма в печени и повышения их концентрации в плазме).\u003Cbr\u003EМиелотоксические лекарственные средства усиливают проявление генатотоксичности препарата."},{"name":"Регистрационный номер","value":"ЛП-001070"},{"name":"Дата государственной регистрации","value":"18.04.2023"},{"name":"Владелец регистрационного удостоверения","value":"Тюменский химико-фармацевтический завод","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["34324371:35649313","7893318:16138914"]}}},{"name":"Изготовитель","value":"Тюменский химико-фармацевтический завод"},{"name":"Название препарата","value":"Левомицетин","transition":{"type":"catalog","params":{"categorySlug":"antibiotiki-protivomikrobnye-i-protivoparazitarnye-sredstva","categoryId":"15756919","navnodeId":"72512","glfilters":["17796364:17880265"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"13607064863574279175":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Назначение","value":"инфекции мочевыводящих и желчевыводящих путей"},{"name":"Органы и системы","value":"желчный пузырь и желчевыводящие пути"},{"name":"Показания к применению","value":"Инфекции мочевыводящих и желчевыводящих путей, вызванные чувствительными микроорганизмами."},{"name":"Противопоказания","value":"Повышенная чувствительность к хлорамфениколу или другим компонентам препарата, угнетение костномозгового кроветворения, острая интермиттирующая порфирия, дефицит глюкозо-6-фосфатдегидрогеназы, печеночная и/или почечная недостаточность, беременность, период лактации, дети младше 3-х лет и с массой тела менее 20 кг."},{"name":"Состав","value":"Состав на одну таблетку\u003Cbr\u003EДействующее вещество: хлорамфеникол - 500 мг.\u003Cbr\u003EВспомогательные вещества: крахмал картофельный - 39,0 мг; повидон К30 - 5,5 мг; кальция стеарат - 5,5 мг."},{"name":"Действующее вещество","value":"Хлорамфеникол"},{"name":"Способ применения и дозы","value":"Внутрь (за 30 мин до еды, а при развитии тошноты и рвоты - через 1 ч после еды) 3-4 раза в сутки.\u003Cbr\u003EРазовая доза для взрослых 250 - 500 мг, суточная - 2000 мг.\u003Cbr\u003EДетям старше 3-х лет и с массой тела более 20 кг применяют по 12,5 мг/кг каждые 6 ч или по 25 мг/кг каждые 12 ч, (под контролем концентрации препарата в сыворотке крови).\u003Cbr\u003EСредняя продолжительность лечения - 8-10 дней."},{"name":"Побочные действия","value":"Со стороны пищеварительной системы: диспепсия, тошнота, рвота (вероятность развития снижается при приеме через 1 ч после еды), диарея, раздражение слизистой оболочки полости рта и зева, дисбактериоз (подавление нормальной микрофлоры).\u003Cbr\u003EСо стороны органов кроветворения: ретикулоцитопения, лейкопения, гранулоцитопения, тромбоцитотопения, эритроцитопения; апластическая анемия, агранулоцитоз.\u003Cbr\u003EСо стороны нервной системы: психомоторные расстройства, депрессия, спутанность сознания, периферический неврит, неврит зрительного нерва, зрительные и слуховые галлюцинации, снижение остроты зрения и слуха, головная боль.\u003Cbr\u003EАллергические реакции: кожная сыпь, ангионевротический отек.\u003Cbr\u003EПрочие: вторичная грибковая инфекция."},{"name":"Фармакологическое действие","value":"Фармакодинамика:\u003Cbr\u003EБактериостатический антибиотик широкого спектра действия, нарушает процесс синтеза белка в микробной клетке на стадии переноса аминокислот т-РНК на рибосомы.\u003Cbr\u003EЭффективен в отношении штаммов бактерий, устойчивых к пенициллину, тетрациклинам, сульфаниламидам.\u003Cbr\u003EАктивен в отношении многих грамположительных и грамотрицательных бактерий, возбудителей гнойных, кишечных инфекций, менингококковой инфекции: Escherichia coli, Shigella dysenteria, Shigella flexneri spp., Shigella boydii spp., Shigella sonnei, Salmonella spp. (в т. ч. Salmonella typhi, Salmonella paratyphi), Staphylococcus spp., Streptocjccus spp. (в т. ч. Streptocjccus pneumonia), Neisseria meningitides, Neisseria gonorrhoeae, ряда штаммов Proteus spp., Burkholderia pseudomallei, Rickettsia spp., Treponema spp., Leptospira spp., Chlamydia spp. (в т. ч. Chlamydia trachomatis), Coxiella burnetii, Ehrlicha canis, Bacteroides fragilis, Klebsiella pneumonia, Haemophilus influenza. He действует на кислотоустойчивые бактерии (в т. ч. Mycobacterium tuberculosis), анаэробы, устойчивые к метицилину штаммы стафилококков, Acinetobacter, Enterobacter, Serratia marcescent, индолположительные штаммы Proteus spp., Pseudomonas aeruginosa spp., простейшие и грибы. Устойчивость микроорганизмов развивается медленно.\u003Cbr\u003EФармакокинетика:\u003Cbr\u003EАбсорбция - 90 % (быстрая и почти полная). \u003Cbr\u003E Биодоступность - 80 % после приема внутрь и 70 % - после в/м введения. \u003Cbr\u003E Связь с белками плазмы - 50-60 %, у недоношенных новорожденных - 32 %. \u003Cbr\u003EВремя достижения максимальной концентрации (ТСmах) после перорального приема - 1-3 ч, после в/в введения -1-1,5 ч. \u003Cbr\u003EОбъем распределения - 0,6-1 л/кг.\u003Cbr\u003EТерапевтическая концентрация в крови сохраняется в течение 4-5 ч после приема.\u003Cbr\u003EХорошо проникает в жидкости и ткани организма. \u003Cbr\u003EНаибольшие его концентрации создаются в печени и почках. В желчи обнаруживается до 30 % от введенной дозы. \u003Cbr\u003EМаксимальная концентрация (Сmах) в\u003Cbr\u003Eспинномозговой жидкости (СМЖ) определяется через 4-5 ч после однократного приема внутрь и может достигать при отсутствии воспаления мозговых оболочек 21-50 % от максимальной концентрации (Сmах) в плазме и 45-89 % - при наличии воспаления мозговых оболочек. Проходит через плацентарный барьер, концентрации в сыворотке крови плода могут составлять 30-80 % от таковой в крови матери. \u003Cbr\u003E Проникает в грудное молоко.\u003Cbr\u003EОсновное количество (90 %) метаболизируется в печени. \u003Cbr\u003EВ кишечнике под влиянием кишечных бактерий гидролизуется с образованием неактивных метаболитов.\u003Cbr\u003EВыводится в течение 24 ч почками - 90 % (путем клубочковой фильтрации - 5-10 % в неизменном виде, путем канальцевой секреции в виде неактивных метаболитов - 80 %), через кишечник - 1-3 %.\u003Cbr\u003E Период полувыведения у взрослых 1,5-3,5 ч, при нарушении функции почек - 3-11 ч. \u003Cbr\u003EПериод полувыведения у детей от 3 лет до 16 лет - 3-6,5 ч. Слабо выводится в ходе гемодиализа."},{"name":"Фармакологическая группа","value":"антибиотики"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 3 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °C.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: угнетение костномозгового кроветворения, желудочно-кишечные расстройства, поражение печени и почек, нейропатия (в том числе зрительного нерва) и ретинопатия.\u003Cbr\u003EЛечение: гемосорбция, симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения необходимо соблюдать осторожность при управлении транспортными средствами и занятии другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"При одновременном приеме этанола возможно развитие дисульфирамоподобной реакции (гиперемия кожных покровов, тахикардия, тошнота, рвота, рефлекторный кашель, судороги).\u003Cbr\u003EВ процессе лечения необходим систематический контроль картины периферической крови."},{"name":"Взаимодействие","value":"Подавляет ферментную систему цитохрома Р450, поэтому при одновременном применении с фенобарбиталом, фенитоином, непрямыми антикоагулянтами отмечается ослабление метаболизма этих лекарственных средств, замедление выведения и повышение их концентрации в плазме. \u003Cbr\u003EПри одновременном применении с эритромицином, клиндамицином, линкомицином отмечается взаимное ослабление действия за счет того, что хлорамфеникол может вытеснять эти лекарственные средства из связанного состояния или препятствовать их связыванию с субъединицей 50S бактериальных рибосом.\u003Cbr\u003EОдновременное назначение с лекарственными средствами, угнетающими кроветворение (сульфаниламиды, цитостатики), влияющими на обмен веществ в печени, с лучевой терапией увеличивает риск развития побочного действия.\u003Cbr\u003EПри назначении с пероральными гипогликемическими лекарственными средствами отмечается усиление их действия (за счет подавления метаболизма в печени и повышения их концентрации в плазме).\u003Cbr\u003EМиелотоксические лекарственные средства усиливают проявление генатотоксичности препарата."},{"name":"Регистрационный номер","value":"ЛП-001070"},{"name":"Дата государственной регистрации","value":"18.04.2023"},{"name":"Владелец регистрационного удостоверения","value":"Тюменский химико-фармацевтический завод"},{"name":"Изготовитель","value":"Тюменский химико-фармацевтический завод"},{"name":"Название препарата","value":"Левомицетин"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_10154237956166155573"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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110 ₽

Скидка: 31%
–31 %
Вместо:160 ₽
  • 11-13 июня, самовывоз • 0 ₽
POLZAru
Рейтинг 4.9 из 5
38Котзывов
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Ещё может подойти

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Инструкция

Показания к применению

Инфекции мочевыводящих и желчевыводящих путей, вызванные чувствительными микроорганизмами.

Противопоказания

Повышенная чувствительность к хлорамфениколу или другим компонентам препарата, угнетение костномозгового кроветворения, острая интермиттирующая порфирия, дефицит глюкозо-6-фосфатдегидрогеназы, печеночная и/или почечная недостаточность, беременность, период лактации, дети младше 3-х лет и с массой тела менее 20 кг.

Способ применения и дозы

Внутрь (за 30 мин до еды, а при развитии тошноты и рвоты - через 1 ч после еды) 3-4 раза в сутки.
Разовая доза для взрослых 250 - 500 мг, суточная - 2000 мг.
Детям старше 3-х лет и с массой тела более 20 кг применяют по 12,5 мг/кг каждые 6 ч или по 25 мг/кг каждые 12 ч, (под контролем концентрации препарата в сыворотке крови).
Средняя продолжительность лечения - 8-10 дней.
Полная инструкция
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Левомицетин-ЛекТ таб.
Левомицетин-ЛекТ таб., 500 мг, 10 шт.
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Задать вопрос
Инструкция

110 ₽

Скидка: 31%
–31 %
Вместо:160 ₽
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Покупатели пока не оценили товар
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