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Описание

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Алфупрост МР таб. пролонг. высвоб., 10 мг, 30 шт.

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5.0
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Коротко о товаре

Артикул Маркета
3123246193
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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смесь для создания таблетки путем компрессии: лактоза безводная 7,00 мг, гипромеллоза 85,00 мг, гипролоза 155,00 мг, повидон (РVР-К 30) 13,00 мг, кремния диоксид коллоидный 1,00 мг, тальк 2,00 мг, магния стеарат 2,00 мг."},{"name":"Действующее вещество","value":"Алфузозин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27144131:28709874"]}}},{"name":"Способ применения и дозы","value":"Препарат предназначен для приема внутрь. Пациенты должны проглатывать таблетку целиком. Запрещается измельчать, раздавливать, разжевывать, размалывать таблетку в порошок. Эти действия могут привести к ненадлежащему высвобождению алфузозина из таблетки и его абсорбции, что повышает риск развития нежелательных реакций (см. раздел «Особые указания»).\u003Cbr\u003EЛечение функциональных симптомов доброкачественной гиперплазии предстательной железы Рекомендованная доза составляет: 1 таблетка (10 мг) ежедневно, после еды.\u003Cbr\u003EПрименение в качестве вспомогательного средства при использовании катетера при острой задержке мочи, связанной с доброкачественной гиперплазией предстательной железы Рекомендованная доза - 1 таблетка (10 мг) в сутки, после еды, начиная с первого дня катетеризации.\u003Cbr\u003EПрепарат применяют в течение 3-4 суток, то есть, 2-3 дня во время нахождения катетера в уретре и 1 день после его удаления."},{"name":"Побочные действия","value":"По частоте побочные эффекты были разделены согласно критериям Всемирной Организации Здравоохранения (ВОЗ) на следующие категории:\u003Cbr\u003Eочень часто (\u003E 1: 10);\u003Cbr\u003Eчасто (\u003E 1: 100 и \u003C 1: 10);\u003Cbr\u003Eнечасто (\u003E 1:1000 и \u003C 1: 100);\u003Cbr\u003Eредко (\u003E 1:10000 и \u003C 1: 1000);\u003Cbr\u003Eочень редко (\u003C 1: 10000) (включая отдельные случаи); неизвестная частота (по имеющимся данным установить частоту возникновения НР не представляется возможным).\u003Cbr\u003E Нарушения со стороны крови и лимфатической системы\u003Cbr\u003E Неизвестная частота: тромбоцитопения.\u003Cbr\u003EНарушения со стороны сердца\u003Cbr\u003EНечасто: тахикардия, ощущение сердцебиения.\u003Cbr\u003EОчень редко: возможное учащение или утяжеление приступов стенокардии (см. разделы «С осторожностью», «Особые указания»)\u003Cbr\u003EНеизвестная частота: фибрилляция предсердий.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003EНечасто: нарушение зрения.\u003Cbr\u003EНеизвестная частота: интраоперационный синдром вялой радужки (см. раздел «Особые указания»).\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EЧасто: астения, недомогание.\u003Cbr\u003EНечасто: отеки, боль в груди.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003E Часто: тошнота, боль в животе.\u003Cbr\u003EНечасто: диарея.\u003Cbr\u003EНеизвестная частота: рвота.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003EНеизвестная частота: гепатоцеллюлярная желтуха, холестаз и связанные с ним заболевания печени.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EЧасто: чувство дурноты/головокружение, головная боль.\u003Cbr\u003EНечасто: синкопальное состояние, вертиго, сонливость.\u003Cbr\u003EНеизвестная частота: ишемические нарушения мозгового кровообращения у пациентов с уже имеющейся цереброваскулярной патологией.\u003Cbr\u003EНарушения со стороны половых органов и молочной железы\u003Cbr\u003EНеизвестная частота: приапизм.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения\u003Cbr\u003EНечасто: ринит.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EНечасто: сыпь, зуд.\u003Cbr\u003EОчень редко: крапивница, ангионевротический отек.\u003Cbr\u003EНарушения со стороны сосудов\u003Cbr\u003EНечасто: снижение АД, включая ортостатическую гипотензию, гиперемия кожных покровов."},{"name":"Фармакологическое действие","value":"Алфузозин является производным хиназолина, активным при пероральном применении. Он является селективным антагонистом постсинаптических альфа1-адренорецепторов, расположенных в предстательной железе, треугольнике мочевого пузыря и мочеиспускательном канале. Клинические проявления доброкачественной гипертрофии предстательной железы выражаются в инфравезикальной обструкции мочевыводящих путей, обусловленной, как анатомическими (статическими), так и функциональными (динамическими) факторами. Функциональный компонент обструкции обусловлен возбуждением альфа1-адренорецепторов, приводящим к сокращению гладкой мускулатуры предстательной железы, ее оболочки, треугольника мочевого пузыря и предстательной части уретры, что приводит к увеличению сопротивления оттока мочи из мочевого пузыря и по- видимому, к вторичной нестабильности мочевого пузыря.\u003Cbr\u003EВследствие прямого воздействия на гладкую мускулатуру ткани предстательной железы, связанного с блокадой альфа1-адренорецепторов, алфузозин уменьшает инфравезикальную обструкцию, давление в уретре и сопротивление оттоку мочи во время мочеиспускания. За счет этого алфузозин улучшает отток мочи и облегчает опорожнение мочевого пузыря. Эти благоприятные эффекты на уродинамику ведут к уменьшению симптомов раздражения мочевыводящих путей и симптомов, обусловленных нарушениями оттока мочи у пациентов с доброкачественной гиперплазией предстательной железы. У пациентов с максимальной скоростью оттока мочи (Qmax) \u003C 15 мл/сек алфузозин. уже начиная с первой дозы, значительно увеличивает Qmax (в среднем на 30 %). Кроме того, у пациентов с доброкачественной гипертрофией предстательной железы алфузозин значительно снижает давление в детрузоре мочевого пузыря и увеличивает объем мочи, вызывающий позыв к мочеиспусканию, а также значительно снижает объем остаточной мочи. Эти эффекты приводят к уменьшению обструктивных и ирритативных симптомов доброкачественной гипертрофии предстательной железы. Препарат не оказывает неблагоприятного действия на сексуальную функцию.\u003Cbr\u003E В связи с селективностью действия алфузозина его влияние на альфа1-адренорецепторы сосудов и, соответственно, на артериальное давление (АД), в случае его применения в терапевтических дозах, практически отсутствует."},{"name":"Фармакологическая группа","value":"альфа1-адреноблокатор"},{"name":"Форма выпуска","value":"таблетки с пролонгированным высвобождением"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["35947170:36763744"]}}},{"name":"Пол","value":"для мужчин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["14805991:14805992"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25°С Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы:\u003Cbr\u003EЧрезмерное снижение артериального давления, рефлекторная тахикардия.\u003Cbr\u003EЛечение:\u003Cbr\u003EВ случае передозировки пациент подлежит госпитализации. При передозировке пациент должен находиться в положении «лежа» и ему требуется постоянное мониторирование АД. При снижении АД рекомендуется введение сосудосуживающих средств и плазмозаменителей (для увеличения объема циркулирующей крови). После восстановления АД (устранения гипотонии) необходимо продолжить контроль АД еще приблизительно в течение суток.\u003Cbr\u003EАлфузозин плохо выводится с помощью гемодиализа из-за высокой степени связывания с белками плазмы."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Алфупрост МР не предназначен для применения у женщин."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Необходимо соблюдать осторожность при управлении транспортными средствами и занятиях другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как препарат может вызывать головокружение и другие побочные эффекты, которые могут влиять на указанные способности."},{"name":"Особые указания","value":"В течение нескольких часов после приема алфузозина (как и после приема любых других альфа1-адреноблокаторов) у некоторых лиц, в особенности, у пациентов, принимающих гипотензивные препараты, может развиться ортостатическая гипотензия с клинической симптоматикой (головокружение, резкая слабость, холодный пот) или без нее. При появлении этих явлений пациент должен до их полного исчезновения находиться в горизонтальном положении. Ортостатическая гипотензия обычно бывает преходящей и наблюдается, как правило, в начале приема препарата и обычно не требует отмены лечения.\u003Cbr\u003EПри постмаркетинговом применении препарата у пациентов с факторами риска снижения АД (такими, как заболевания сердца или сопутствующая терапия гипотензивными препаратами) сообщалось о выраженном снижении АД. Риск чрезмерного снижения АД и связанных с ним нежелательных реакций может быть выше у пациентов пожилого возраста.\u003Cbr\u003EПеред началом лечения больной должен быть предупрежден о возможности возникновения описанных выше реакций.\u003Cbr\u003E Следует соблюдать осторожность при применении алфузозина у пациентов с ортостатической гипотензией с клинической симптоматикой или у пациентов, принимающих гипотензивные препараты или нитраты: необходим более тщательный контроль за АД. в том числе, при переходе из горизонтального положения в вертикальное, особенно в начале лечения.\u003Cbr\u003E Следует соблюдать осторожность при применении алфузозина у пациентов с выраженной гипотензивной реакцией в ответ на прием других блокаторов альфа 1 - адренорецепторов в анамнезе.\u003Cbr\u003E Пациентам с коронарной недостаточностью при приеме алфузозина необходимо продолжать антиангинальную терапию. При возобновлении или утяжелении стенокардии лечение алфузозином следует прекратить.\u003Cbr\u003E Следует соблюдать осторожность при применении алфузозина у пациентов с врожденным или приобретенным удлинением интервала QТ или у пациентов, принимающих лекарственные препараты, способные удлинять интервал QТ.\u003Cbr\u003E Во время проведения офтальмологических операций по поводу катаракты у некоторых пациентов, принимающих или принимавших ранее некоторые алфа1-адреноблокаторы, наблюдалось развитие интраоперационного синдрома вялой радужки (вариант синдрома узкого зрачка). Хотя риск развития такого осложнения при приеме препарата Алфупрост МР представляется очень низким, перед проведением операции по поводу катаракты хирург-офтальмолог должен быть проинформирован о том, что пациент принимает альфа1- адреноблокаторы или принимал их ранее, так как развитие интраоперационного синдрома вялой радужки может увеличивать количество осложнений при этом оперативном вмешательстве. Офтальмологи должны быть готовы к возможному изменению методики оперативного вмешательства.\u003Cbr\u003E Пациентов следует предупредить о том, что запрещается измельчать, раздавливать, разжевывать, размалывать таблетку в порошок. Такие действия могут привести к чрезмерному высвобождению и абсорбции препарата, вследствие чего возможно быстрое развитие побочных эффектов, что особенно опасно у пациентов с цереброваскулярными расстройствами, протекающими с соответствующими симптомами, а также у тех пациентов, у которых цереброваскулярные расстройства протекают бессимптомно, так как у таких пациентов при резком снижении АД возможно усиление ишемии головного мозга.\u003Cbr\u003E Есть сообщения о случаях развития приапизма (длительной болезненной эрекции полового члена, не связанной с сексуальной активностью) на фоне терапии альфа1- адреноблокаторами, включая алфузозин. Если терапия приапизма не была проведена незамедлительно, это может привести к повреждению тканей полового члена и необратимой утрате потенции. Пациентов следует информировать о серьезности этого состояния (см. раздел «Побочное действие») и необходимости немедленного обращения за медицинской помощью в случае сохранения эрекции в течение более 4-х часов.\u003Cbr\u003E С осторожностью\u003Cbr\u003E У пациентов, принимающих гипотензивные препараты или нитраты (возможно развитие ортостатической гипотонии, как протекающей бессимптомно, так и симптоматической, сопровождающейся головокружением, слабостью, холодным потом).\u003Cbr\u003E У пациентов пожилого возраста (старше 75 лет).\u003Cbr\u003E У пациентов с выраженной гипотензивной реакцией на другие альфа1- адреноблокаторы в анамнезе.\u003Cbr\u003E У пациентов с ортостатической гипотензией с клиническими проявлениями.\u003Cbr\u003E У пациентов с ишемической болезнью сердца, стенокардией (возможно учащение и утяжеление приступов стенокардии).\u003Cbr\u003E У пациентов с врожденным или приобретенным удлинением интервала QТ или у пациентов, принимающих лекарственные препараты, увеличивающие продолжительность интервала QТ.\u003Cbr\u003E У пациентов с ишемией головного мозга.\u003Cbr\u003E С ингибиторами изофермента СYР4АЗ (кетоконазол, итраконазол, ритонавир) (возможно увеличение концентрации алфузозина в плазме крови)."},{"name":"Взаимодействие","value":"Противопоказанные комбинации\u003Cbr\u003E С блокаторами альфа1-рецепторов (празозин, урапидил): усиление гипотензивного эффекта, риск развития тяжелой ортостатической гипотензии (см. раздел «Противопоказания »).\u003Cbr\u003EВзаимодействия, которые следует принимать во внимание\u003Cbr\u003EС гипотензивными препаратами: усиление гипотензивного эффекта и риск развития ортостатической гипотензии (аддитивное действие) (см. раздел «Особые указания»).\u003Cbr\u003EС нитратами: увеличение риска развития рефлекторной тахикардии и снижения АД.\u003Cbr\u003E Со средствами для ингаляционной и неингаляционной общей анестезии: возможна нестабильность АД во время общей анестезии.\u003Cbr\u003E С ингибиторами изофермента СYР4АЗ (кетоконазол, итраконазол, ритонавир): возможно увеличение концентрации алфузозина в плазме крови. При сочетании алфузозина в дозе 10 мг в сутки с курсовым применением кетоконазола в дозе 200 мг в сутки в течение 7 дней Сmах и АUС алфузозина увеличиваются в 2,1 раза и 2,46 раз, соответственно, а при его сочетании с курсовым применением кетоконазола в дозе 400 мг в сутки в течение 8 дней Сmах и АUС алфузозина увеличиваются в 2,3 раза и 3,0 раза, соответственно (см. раздел «С осторожностью »)."},{"name":"Регистрационный номер","value":"ЛП-001176"},{"name":"Дата государственной регистрации","value":"10.01.2020"},{"name":"Владелец регистрационного удостоверения","value":"Sun Pharmaceutical Industries Ltd","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["34324371:35649313","7893318:13888155"]}}},{"name":"Изготовитель","value":"Sun Pharmaceutical Industries Ltd"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Алфупрост","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["17796364:18045579"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"2616786431582567855":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"выделительная система, половая система, половые железы"},{"name":"Назначение","value":"доброкачественная гиперплазия предстательной железы"},{"name":"Показания к применению","value":"Лечение функциональных симптомов при доброкачественной гиперплазии предстательной железы.\u003Cbr\u003EВ качестве вспомогательного средства при использовании катетера при острой задержке мочи, связанной с доброкачественной гиперплазией предстательной железы."},{"name":"Противопоказания","value":"Повышенная чувствительность к алфузозину и/или другим компонентам препарата.\u003Cbr\u003E Ортостатическая гипотензия.\u003Cbr\u003EТяжелые нарушения функции печени.\u003Cbr\u003E Тяжелая почечная недостаточность (клиренс креатинина \u003C30 мл/мин).\u003Cbr\u003E Одновременный прием других альфа1-адреноблокаторов.\u003Cbr\u003EДетский возраст до 18 лет."},{"name":"Состав","value":"Каждая таблетка пролонгированного действия содержит:\u003Cbr\u003EДействующее вещество:\u003Cbr\u003Eалфузозина гидрохлорид (в составе гранул) 10,00 мг.\u003Cbr\u003EВспомогательные вещества:\u003Cbr\u003Eгранулы: лактоза безводная 70,00 мг, кремния диоксид коллоидный 2,00 мг, повидон (РVР-К 30) 2,00 мг, тальк 0.50 мг, магния стеарат 0,50 мг; смесь для создания таблетки путем компрессии: лактоза безводная 7,00 мг, гипромеллоза 85,00 мг, гипролоза 155,00 мг, повидон (РVР-К 30) 13,00 мг, кремния диоксид коллоидный 1,00 мг, тальк 2,00 мг, магния стеарат 2,00 мг."},{"name":"Действующее вещество","value":"Алфузозин"},{"name":"Способ применения и дозы","value":"Препарат предназначен для приема внутрь. Пациенты должны проглатывать таблетку целиком. Запрещается измельчать, раздавливать, разжевывать, размалывать таблетку в порошок. Эти действия могут привести к ненадлежащему высвобождению алфузозина из таблетки и его абсорбции, что повышает риск развития нежелательных реакций (см. раздел «Особые указания»).\u003Cbr\u003EЛечение функциональных симптомов доброкачественной гиперплазии предстательной железы Рекомендованная доза составляет: 1 таблетка (10 мг) ежедневно, после еды.\u003Cbr\u003EПрименение в качестве вспомогательного средства при использовании катетера при острой задержке мочи, связанной с доброкачественной гиперплазией предстательной железы Рекомендованная доза - 1 таблетка (10 мг) в сутки, после еды, начиная с первого дня катетеризации.\u003Cbr\u003EПрепарат применяют в течение 3-4 суток, то есть, 2-3 дня во время нахождения катетера в уретре и 1 день после его удаления."},{"name":"Побочные действия","value":"По частоте побочные эффекты были разделены согласно критериям Всемирной Организации Здравоохранения (ВОЗ) на следующие категории:\u003Cbr\u003Eочень часто (\u003E 1: 10);\u003Cbr\u003Eчасто (\u003E 1: 100 и \u003C 1: 10);\u003Cbr\u003Eнечасто (\u003E 1:1000 и \u003C 1: 100);\u003Cbr\u003Eредко (\u003E 1:10000 и \u003C 1: 1000);\u003Cbr\u003Eочень редко (\u003C 1: 10000) (включая отдельные случаи); неизвестная частота (по имеющимся данным установить частоту возникновения НР не представляется возможным).\u003Cbr\u003E Нарушения со стороны крови и лимфатической системы\u003Cbr\u003E Неизвестная частота: тромбоцитопения.\u003Cbr\u003EНарушения со стороны сердца\u003Cbr\u003EНечасто: тахикардия, ощущение сердцебиения.\u003Cbr\u003EОчень редко: возможное учащение или утяжеление приступов стенокардии (см. разделы «С осторожностью», «Особые указания»)\u003Cbr\u003EНеизвестная частота: фибрилляция предсердий.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003EНечасто: нарушение зрения.\u003Cbr\u003EНеизвестная частота: интраоперационный синдром вялой радужки (см. раздел «Особые указания»).\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EЧасто: астения, недомогание.\u003Cbr\u003EНечасто: отеки, боль в груди.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003E Часто: тошнота, боль в животе.\u003Cbr\u003EНечасто: диарея.\u003Cbr\u003EНеизвестная частота: рвота.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003EНеизвестная частота: гепатоцеллюлярная желтуха, холестаз и связанные с ним заболевания печени.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EЧасто: чувство дурноты/головокружение, головная боль.\u003Cbr\u003EНечасто: синкопальное состояние, вертиго, сонливость.\u003Cbr\u003EНеизвестная частота: ишемические нарушения мозгового кровообращения у пациентов с уже имеющейся цереброваскулярной патологией.\u003Cbr\u003EНарушения со стороны половых органов и молочной железы\u003Cbr\u003EНеизвестная частота: приапизм.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения\u003Cbr\u003EНечасто: ринит.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EНечасто: сыпь, зуд.\u003Cbr\u003EОчень редко: крапивница, ангионевротический отек.\u003Cbr\u003EНарушения со стороны сосудов\u003Cbr\u003EНечасто: снижение АД, включая ортостатическую гипотензию, гиперемия кожных покровов."},{"name":"Фармакологическое действие","value":"Алфузозин является производным хиназолина, активным при пероральном применении. Он является селективным антагонистом постсинаптических альфа1-адренорецепторов, расположенных в предстательной железе, треугольнике мочевого пузыря и мочеиспускательном канале. Клинические проявления доброкачественной гипертрофии предстательной железы выражаются в инфравезикальной обструкции мочевыводящих путей, обусловленной, как анатомическими (статическими), так и функциональными (динамическими) факторами. Функциональный компонент обструкции обусловлен возбуждением альфа1-адренорецепторов, приводящим к сокращению гладкой мускулатуры предстательной железы, ее оболочки, треугольника мочевого пузыря и предстательной части уретры, что приводит к увеличению сопротивления оттока мочи из мочевого пузыря и по- видимому, к вторичной нестабильности мочевого пузыря.\u003Cbr\u003EВследствие прямого воздействия на гладкую мускулатуру ткани предстательной железы, связанного с блокадой альфа1-адренорецепторов, алфузозин уменьшает инфравезикальную обструкцию, давление в уретре и сопротивление оттоку мочи во время мочеиспускания. За счет этого алфузозин улучшает отток мочи и облегчает опорожнение мочевого пузыря. Эти благоприятные эффекты на уродинамику ведут к уменьшению симптомов раздражения мочевыводящих путей и симптомов, обусловленных нарушениями оттока мочи у пациентов с доброкачественной гиперплазией предстательной железы. У пациентов с максимальной скоростью оттока мочи (Qmax) \u003C 15 мл/сек алфузозин. уже начиная с первой дозы, значительно увеличивает Qmax (в среднем на 30 %). Кроме того, у пациентов с доброкачественной гипертрофией предстательной железы алфузозин значительно снижает давление в детрузоре мочевого пузыря и увеличивает объем мочи, вызывающий позыв к мочеиспусканию, а также значительно снижает объем остаточной мочи. Эти эффекты приводят к уменьшению обструктивных и ирритативных симптомов доброкачественной гипертрофии предстательной железы. Препарат не оказывает неблагоприятного действия на сексуальную функцию.\u003Cbr\u003E В связи с селективностью действия алфузозина его влияние на альфа1-адренорецепторы сосудов и, соответственно, на артериальное давление (АД), в случае его применения в терапевтических дозах, практически отсутствует."},{"name":"Фармакологическая группа","value":"альфа1-адреноблокатор"},{"name":"Форма выпуска","value":"таблетки с пролонгированным высвобождением"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Пол","value":"для мужчин"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25°С Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы:\u003Cbr\u003EЧрезмерное снижение артериального давления, рефлекторная тахикардия.\u003Cbr\u003EЛечение:\u003Cbr\u003EВ случае передозировки пациент подлежит госпитализации. При передозировке пациент должен находиться в положении «лежа» и ему требуется постоянное мониторирование АД. При снижении АД рекомендуется введение сосудосуживающих средств и плазмозаменителей (для увеличения объема циркулирующей крови). После восстановления АД (устранения гипотонии) необходимо продолжить контроль АД еще приблизительно в течение суток.\u003Cbr\u003EАлфузозин плохо выводится с помощью гемодиализа из-за высокой степени связывания с белками плазмы."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Алфупрост МР не предназначен для применения у женщин."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Необходимо соблюдать осторожность при управлении транспортными средствами и занятиях другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как препарат может вызывать головокружение и другие побочные эффекты, которые могут влиять на указанные способности."},{"name":"Особые указания","value":"В течение нескольких часов после приема алфузозина (как и после приема любых других альфа1-адреноблокаторов) у некоторых лиц, в особенности, у пациентов, принимающих гипотензивные препараты, может развиться ортостатическая гипотензия с клинической симптоматикой (головокружение, резкая слабость, холодный пот) или без нее. При появлении этих явлений пациент должен до их полного исчезновения находиться в горизонтальном положении. Ортостатическая гипотензия обычно бывает преходящей и наблюдается, как правило, в начале приема препарата и обычно не требует отмены лечения.\u003Cbr\u003EПри постмаркетинговом применении препарата у пациентов с факторами риска снижения АД (такими, как заболевания сердца или сопутствующая терапия гипотензивными препаратами) сообщалось о выраженном снижении АД. Риск чрезмерного снижения АД и связанных с ним нежелательных реакций может быть выше у пациентов пожилого возраста.\u003Cbr\u003EПеред началом лечения больной должен быть предупрежден о возможности возникновения описанных выше реакций.\u003Cbr\u003E Следует соблюдать осторожность при применении алфузозина у пациентов с ортостатической гипотензией с клинической симптоматикой или у пациентов, принимающих гипотензивные препараты или нитраты: необходим более тщательный контроль за АД. в том числе, при переходе из горизонтального положения в вертикальное, особенно в начале лечения.\u003Cbr\u003E Следует соблюдать осторожность при применении алфузозина у пациентов с выраженной гипотензивной реакцией в ответ на прием других блокаторов альфа 1 - адренорецепторов в анамнезе.\u003Cbr\u003E Пациентам с коронарной недостаточностью при приеме алфузозина необходимо продолжать антиангинальную терапию. При возобновлении или утяжелении стенокардии лечение алфузозином следует прекратить.\u003Cbr\u003E Следует соблюдать осторожность при применении алфузозина у пациентов с врожденным или приобретенным удлинением интервала QТ или у пациентов, принимающих лекарственные препараты, способные удлинять интервал QТ.\u003Cbr\u003E Во время проведения офтальмологических операций по поводу катаракты у некоторых пациентов, принимающих или принимавших ранее некоторые алфа1-адреноблокаторы, наблюдалось развитие интраоперационного синдрома вялой радужки (вариант синдрома узкого зрачка). Хотя риск развития такого осложнения при приеме препарата Алфупрост МР представляется очень низким, перед проведением операции по поводу катаракты хирург-офтальмолог должен быть проинформирован о том, что пациент принимает альфа1- адреноблокаторы или принимал их ранее, так как развитие интраоперационного синдрома вялой радужки может увеличивать количество осложнений при этом оперативном вмешательстве. Офтальмологи должны быть готовы к возможному изменению методики оперативного вмешательства.\u003Cbr\u003E Пациентов следует предупредить о том, что запрещается измельчать, раздавливать, разжевывать, размалывать таблетку в порошок. Такие действия могут привести к чрезмерному высвобождению и абсорбции препарата, вследствие чего возможно быстрое развитие побочных эффектов, что особенно опасно у пациентов с цереброваскулярными расстройствами, протекающими с соответствующими симптомами, а также у тех пациентов, у которых цереброваскулярные расстройства протекают бессимптомно, так как у таких пациентов при резком снижении АД возможно усиление ишемии головного мозга.\u003Cbr\u003E Есть сообщения о случаях развития приапизма (длительной болезненной эрекции полового члена, не связанной с сексуальной активностью) на фоне терапии альфа1- адреноблокаторами, включая алфузозин. Если терапия приапизма не была проведена незамедлительно, это может привести к повреждению тканей полового члена и необратимой утрате потенции. Пациентов следует информировать о серьезности этого состояния (см. раздел «Побочное действие») и необходимости немедленного обращения за медицинской помощью в случае сохранения эрекции в течение более 4-х часов.\u003Cbr\u003E С осторожностью\u003Cbr\u003E У пациентов, принимающих гипотензивные препараты или нитраты (возможно развитие ортостатической гипотонии, как протекающей бессимптомно, так и симптоматической, сопровождающейся головокружением, слабостью, холодным потом).\u003Cbr\u003E У пациентов пожилого возраста (старше 75 лет).\u003Cbr\u003E У пациентов с выраженной гипотензивной реакцией на другие альфа1- адреноблокаторы в анамнезе.\u003Cbr\u003E У пациентов с ортостатической гипотензией с клиническими проявлениями.\u003Cbr\u003E У пациентов с ишемической болезнью сердца, стенокардией (возможно учащение и утяжеление приступов стенокардии).\u003Cbr\u003E У пациентов с врожденным или приобретенным удлинением интервала QТ или у пациентов, принимающих лекарственные препараты, увеличивающие продолжительность интервала QТ.\u003Cbr\u003E У пациентов с ишемией головного мозга.\u003Cbr\u003E С ингибиторами изофермента СYР4АЗ (кетоконазол, итраконазол, ритонавир) (возможно увеличение концентрации алфузозина в плазме крови)."},{"name":"Взаимодействие","value":"Противопоказанные комбинации\u003Cbr\u003E С блокаторами альфа1-рецепторов (празозин, урапидил): усиление гипотензивного эффекта, риск развития тяжелой ортостатической гипотензии (см. раздел «Противопоказания »).\u003Cbr\u003EВзаимодействия, которые следует принимать во внимание\u003Cbr\u003EС гипотензивными препаратами: усиление гипотензивного эффекта и риск развития ортостатической гипотензии (аддитивное действие) (см. раздел «Особые указания»).\u003Cbr\u003EС нитратами: увеличение риска развития рефлекторной тахикардии и снижения АД.\u003Cbr\u003E Со средствами для ингаляционной и неингаляционной общей анестезии: возможна нестабильность АД во время общей анестезии.\u003Cbr\u003E С ингибиторами изофермента СYР4АЗ (кетоконазол, итраконазол, ритонавир): возможно увеличение концентрации алфузозина в плазме крови. При сочетании алфузозина в дозе 10 мг в сутки с курсовым применением кетоконазола в дозе 200 мг в сутки в течение 7 дней Сmах и АUС алфузозина увеличиваются в 2,1 раза и 2,46 раз, соответственно, а при его сочетании с курсовым применением кетоконазола в дозе 400 мг в сутки в течение 8 дней Сmах и АUС алфузозина увеличиваются в 2,3 раза и 3,0 раза, соответственно (см. раздел «С осторожностью »)."},{"name":"Регистрационный номер","value":"ЛП-001176"},{"name":"Дата государственной регистрации","value":"10.01.2020"},{"name":"Владелец регистрационного удостоверения","value":"Sun Pharmaceutical Industries Ltd"},{"name":"Изготовитель","value":"Sun Pharmaceutical Industries Ltd"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Алфупрост"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_10775173941792243379"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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313 ₽

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    Просталь капс., 0.3 г, 60 шт., 1 уп.

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  • Простасабаль капс., 30 шт.
    ВАМ–25 %
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    Простасабаль капс., 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 403 оценки
    Цена 387 ₽ вместо 515
    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  • Урефрон таб., 40 г, 50 шт., нейтральный, 1 уп.
    –20 %
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    Урефрон таб., 40 г, 50 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 62 оценки
    Цена 308 ₽ вместо 385
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таб., 40 г, 50 шт., нейтральный, 1 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  • Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.
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    Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 19 оценок
    Цена 431 ₽
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  • ПростаНорм таб. п/о, 200 мг, 30 шт.
    –1 %
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    ПростаНорм таб. п/о, 200 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 104 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 403 ₽ вместо 407
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  • Афалаза таб. д/рассас., 100 шт.
    –1 %
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    Афалаза таб. д/рассас., 100 шт.

    Рейтинг товара: 4.7 из 5
    на основе 88 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 056 ₽ вместо 1 067
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  • Тадалафил-СЗ таб. п/о плен., 20 мг, 8 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-irnn0rluc6/toggleWishlist":{"skuId":"662554162","productId":1430912592,"offerId":"jw0xXug4VhhQ3wERwUvYDg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ36ig06Snqbh4EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI0PynqgUQsoz3uwIYrt7QByDu3MEH","sign":"+zBWtI0S8fM1IoHshH2gtdgqc9SLWqhLJmqoFEiEInY="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-irnn0rluc6/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тадалафил-СЗ таб. п/о плен., 20 мг, 8 шт.

    Рейтинг товара: 4.7 из 5
    на основе 500 оценок
    Цена 386 ₽
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  • Афала таб. д/рассас., 100 шт.
    –2 %
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    Афала таб. д/рассас., 100 шт.

    Рейтинг товара: 4.5 из 5
    на основе 33 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 785 ₽ вместо 801
    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  • Простамол Уно капс., 320 мг, 30 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-umv7phcby0b/toggleWishlist":{"skuId":"228067031","productId":1430912474,"offerId":"4YnAzGfxILkQM9_B6AX3PA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ36ig06Snqbh4EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI2vunqgUQ143gbBij39AHIO7cwQc=","sign":"JpHgisgqWlZkLWC6g3xy/I1M5eRXhSnEmt/BEZygq98="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-umv7phcby0b/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Простамол Уно капс., 320 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 111 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 872 ₽ вместо 881
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  • Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.
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    Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.

    Рейтинг товара: 4.6 из 5
    на основе 1043 оценки
    Цена 216 ₽
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  • Канефрон Н таб.п/о, 60 шт.
    –1 %
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    Канефрон Н таб.п/о, 60 шт.

    Рейтинг товара: 4.9 из 5
    на основе 390 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 791 ₽ вместо 799
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  • Аденопросин супп. рект., 29 мг, 10 шт.
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    Аденопросин супп. рект., 29 мг, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 5 оценок
    Цена 1 439 ₽
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Инструкция

Показания к применению

Лечение функциональных симптомов при доброкачественной гиперплазии предстательной железы.
В качестве вспомогательного средства при использовании катетера при острой задержке мочи, связанной с доброкачественной гиперплазией предстательной железы.

Противопоказания

Повышенная чувствительность к алфузозину и/или другим компонентам препарата.
Ортостатическая гипотензия.
Тяжелые нарушения функции печени.
Тяжелая почечная недостаточность (клиренс креатинина <30 мл/мин).
Одновременный прием других альфа1-адреноблокаторов.
Детский возраст до 18 лет.

Способ применения и дозы

Препарат предназначен для приема внутрь. Пациенты должны проглатывать таблетку целиком. Запрещается измельчать, раздавливать, разжевывать, размалывать таблетку в порошок. Эти действия могут привести к ненадлежащему высвобождению алфузозина из таблетки и его абсорбции, что повышает риск развития нежелательных реакций (см. раздел «Особые указания»).
Лечение функциональных симптомов доброкачественной гиперплазии предстательной железы Рекомендованная доза составляет: 1 таблетка (10 мг) ежедневно, после еды.
Применение в качестве вспомогательного средства при использовании катетера при острой задержке мочи, связанной с доброкачественной гиперплазией предстательной железы Рекомендованная доза - 1 таблетка (10 мг) в сутки, после еды, начиная с первого дня катетеризации.
Препарат применяют в течение 3-4 суток, то есть, 2-3 дня во время нахождения катетера в уретре и 1 день после его удаления.
Полная инструкция
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Алфупрост МР таб. пролонг. высвоб.
Алфупрост МР таб. пролонг. высвоб., 10 мг, 30 шт.
5.0
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2 вопроса
Инструкция

313 ₽

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5.0
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