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Описание

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ТАМСУЛОЗИН капс. с пролонг. высвоб., 0.4 мг, 90 шт.

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4.3
(14)
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Количество штук в упаковке, шт.: 90

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Коротко о товаре

Артикул Маркета
417394439
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"13665749419564527959":{"specItems":[{"name":"Артикул Маркета","value":"417394439","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"дизурия, доброкачественная гиперплазия предстательной железы","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["36476390:36618913,36617876"]}}},{"name":"действующее вещество","value":"Taмcyлoзин","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27144131:28709724"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"капсулы с пролонгированным высвобождением"},{"name":"способ применения/введения","value":"пероральный","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["35947170:36763744"]}}},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"13665749419564527959":{"specItems":[{"name":"Артикул Маркета","value":"417394439","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Действующее вещество","value":"Taмcyлoзин","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27144131:28709724"]}}},{"name":"Возраст","value":"От 18 лет"},{"name":"Способ применения/введения","value":"Пероральный","transition":{"type":"list","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["35947170:36763744"]}}}]}},"fullSpecs":{"13665749419564527959":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"мочеполовая система"},{"name":"Назначение","value":"дизурия, доброкачественная гиперплазия предстательной железы","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["36476390:36618913,36617876"]}}},{"name":"Показания к применению","value":"Лечение дизурических расстройств, связанных с доброкачественной гиперплазией предстательной железы (ДГПЖ)."},{"name":"Противопоказания","value":"- Гиперчувствительность к тамсулозину и/или к любому из вспомогательных веществ в составе препарата, в том числе, наличие лекарственного ангионевротического отека в анамнезе.\u003Cbr\u003E\n\u003Cbr\u003E\n- Ортостатическая гипотензия (в т.ч. в анамнезе).\u003Cbr\u003E\n\u003Cbr\u003E\n- Печеночная недостаточность тяжелой степени.\u003Cbr\u003E\n\u003Cbr\u003E\n- Возраст до 18 лет.\u003Cbr\u003E\n\u003Cbr\u003E\n- Непереносимость фруктозы, дефицит сахаразы/изомальтазы, синдром глюкозо-галактозной мальабсорбции."},{"name":"Состав","value":"1 капсула содержит:\u003Cbr\u003E\n\u003Cbr\u003E\nтамсулозина гидрохлорид, субстанция-пеллеты, 0,133 % - 300,3 мг.\u003Cbr\u003E\n\u003Cbr\u003E\nСостав пеллет:\u003Cbr\u003E\n\u003Cbr\u003E\nдействующее вещество: тамсулозина гидрохлорид - 0,4 мг;\u003Cbr\u003E\n\u003Cbr\u003E\nвспомогательные вещества: ядро (75 % сахароза и 25 % крахмал) - 220,0 мг: гипромеллоза-Е5 - 1,9132 мг, натрия лаурилсульфат - 0,2 мг, дибутилфталат - 0,2088 мг, тальк - 7,5358 мг;\u003Cbr\u003E\n\u003Cbr\u003E\nоболочка: макрогол-6000 - 6,2058 мг, этилцеллюлоза - 1,7748 мг, метакриловой кислоты и этилакрилата сополимер (1:1) [30 % дисперсия] - 62,0585 мг.\u003Cbr\u003E\n\u003Cbr\u003E\nВспомогательные вещества оболочки капсулы: корпус: желатин - 100 %;\u003Cbr\u003E\n\u003Cbr\u003E\nкрышечка: титана диоксид - 1 %, железа оксид желтый - 0,7 %, индигокармин - 0,15 %, желатин - до 100 %."},{"name":"Действующее вещество","value":"Taмcyлoзин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27144131:28709724"]}}},{"name":"Способ применения и дозы","value":"Внутрь. Принимают по 1 капсуле (0,4 мг) 1 раз в сутки после завтрака, запивая водой. Капсулу не разжевывать, так как это может повлиять на скорость высвобождения тамсулозина.\u003Cbr\u003E\n\u003Cbr\u003E\nПрименение препарата в особых клинических группах пациентов\u003Cbr\u003E\n\u003Cbr\u003E\nУ детей и подростков до 18 лет\u003Cbr\u003E\n\u003Cbr\u003E\nТамсулозин не показан к применению у детей и подростков до 18 лет.\u003Cbr\u003E\n\u003Cbr\u003E\nУ пожилых пациентов\u003Cbr\u003E\n\u003Cbr\u003E\nКоррекции дозы тамсулозина не требуется.\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов с нарушением функции почек\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов с почечной недостаточностью коррекции дозы не требуется. При применении тамсулозина у пациентов с терминальной стадией почечной недостаточности (клиренс креатинина \u003C 10 мл/мин) следует соблюдать меры предосторожности.\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов с нарушением функции печени\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов с печеночной недостаточностью легкой и средней степени тяжести коррекции дозы не требуется. Применение тамсулозина у пациентов с печеночной недостаточностью тяжелой степени противопоказано."},{"name":"Побочные действия","value":"Представленные ниже нежелательные реакции, возможные на фоне терапии тамсулозином, распределены по системно-органным классам с указанием частоты их возникновения согласно рекомендациям ВОЗ:\u003Cbr\u003E\n\u003Cbr\u003E\nочень часто ≥ 1/10;\u003Cbr\u003E\n\u003Cbr\u003E\nчасто от ≥ 1/100 до \u003C 1/10;\u003Cbr\u003E\n\u003Cbr\u003E\nнечасто от ≥ 1/1000 до \u003C 1/100;\u003Cbr\u003E\n\u003Cbr\u003E\nредко от ≥ 1/10000 до \u003C 1/1000;\u003Cbr\u003E\n\u003Cbr\u003E\nочень редко \u003C 1/10000, включая отдельные сообщения;\u003Cbr\u003E\n\u003Cbr\u003E\nчастота неизвестна - по имеющимся данным установить частоту возникновения не представляется возможным.\u003Cbr\u003EОписаны случаи интраоперационной нестабильности радужной оболочки глаза (синдром узкого зрачка) при операции по поводу катаракты и глаукомы у пациентов, принимавших тамсулозин.\u003Cbr\u003E\n\u003Cbr\u003E\nПострегистрационное применение препарата\u003Cbr\u003E\n\u003Cbr\u003E\nПомимо нежелательных реакций, описанным выше, при использовании тамсулозина наблюдались фибрилляция предсердий, аритмия, тахикардия и отдышка. В связи с тем, что данные были получены методом спонтанных сообщений в пострегистрационном периоде применения тамсулозина, определение частоты и причинно-следственной связи данных нежелательных реакций с приемом тамсулозина представляется затруднительным.\u003Cbr\u003E\nПередозировка:\u003Cbr\u003E\nСимптомы\u003Cbr\u003E\n\u003Cbr\u003E\nПередозировка тамсулозина может вызвать серьезное снижение артериального давления и компенсаторную тахикардию.\u003Cbr\u003E\n\u003Cbr\u003E\nЛечение\u003Cbr\u003E\n\u003Cbr\u003E\nСимптоматическое. АД и частота сердечных сокращений могут восстановиться при принятии пациентом горизонтального положения. При отсутствии эффекта можно применить средства, увеличивающие объем циркулирующей крови, и, если необходимо, сосудосуживающие средства. Необходимо контролировать функцию почек. Проведение гемодиализа нецелесообразно, так как тамсулозин в значительной степени связывается с белками плазмы крови.\u003Cbr\u003E\n\u003Cbr\u003E\nДля предотвращения дальнейшего всасывания препарата целесообразно промывание желудка, прием сорбентов (активированного угля) и осмотических слабительных."},{"name":"Фармакологическое действие","value":"Тамсулозин является специфическим блокатором постсинаптических α1- адренорецепторов, находящихся в гладкой мускулатуре предстательной железы, шейки мочевого пузыря и простатической части уретры. Блокада α1- адренорецепторов тамсулозином приводит к снижению тонуса гладких мышц и улучшению оттока мочи. Одновременно уменьшаются как симптомы опорожнения, так и симптомы наполнения, обусловленные повышенным тонусом гладкой мускулатуры и детрузорной гиперактивностью при доброкачественной гиперплазии предстательной железы.\u003Cbr\u003E\n\u003Cbr\u003E\nСпособность тамсулозина воздействовать на α1-А подтип адренорецепторов в 20 раз превосходит его способность взаимодействовать с α1-В подтипом адренорецепторов, которые расположены в гладких мышцах сосудов. Благодаря своей высокой селективности, тамсулозин не вызывает клинически значимого снижения системного артериального давления (АД) как у пациентов с артериальной гипертензией, так и у пациентов с нормальным исходным АД."},{"name":"Фармакологическая группа","value":"альфа1-адреноблокатор"},{"name":"Форма выпуска","value":"капсулы с пролонгированным высвобождением"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["35947170:36763744"]}}},{"name":"Пол","value":"для мужчин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["14805991:14805992"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °С.\u003Cbr\u003E\n\u003Cbr\u003E\nХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003E\n\u003Cbr\u003E\nПередозировка тамсулозина может вызвать серьезное снижение артериального давления и компенсаторную тахикардию.\u003Cbr\u003E\n\u003Cbr\u003E\nЛечение\u003Cbr\u003E\n\u003Cbr\u003E\nСимптоматическое. АД и частота сердечных сокращений могут восстановиться при принятии пациентом горизонтального положения. При отсутствии эффекта можно применить средства, увеличивающие объем циркулирующей крови, и, если необходимо, сосудосуживающие средства. Необходимо контролировать функцию почек. Проведение гемодиализа нецелесообразно, так как тамсулозин в значительной степени связывается с белками плазмы крови.\u003Cbr\u003E\n\u003Cbr\u003E\nДля предотвращения дальнейшего всасывания препарата целесообразно промывание желудка, прием сорбентов (активированного угля) и осмотических слабительных."},{"name":"Применение при беременности и кормлении грудью","value":"Тамсулозин не показан к применению у женщин."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Данные об отрицательном влиянии на способность к управлению транспортными средствами и занятию потенциально опасными видами деятельности отсутствуют. Тем не менее, в связи с возможностью возникновения головокружения, до выяснения индивидуальной реакции пациента, следует воздержаться от занятий, требующих повышенной концентрации внимания и быстроты психомоторных реакций, в том числе от управления транспортными средствами и механизмами."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003E\nУ пациентов с почечной недостаточностью в терминальной стадии (клиренс креатинина менее 10 мл/мин); артериальной гипотензией.\u003Cbr\u003EКак и при применении других α1-адреноблокаторов, на фоне терапии тамсулозином в отдельных случаях может наблюдаться снижение АД, которое иногда может привести к обморочному состоянию. При первых признаках ортостатической гипотензии (головокружение, слабость) пациент должен сесть или лечь и оставаться в этом положении до тех пор, пока указанные симптомы не исчезнут.\u003Cbr\u003E\n\u003Cbr\u003E\nПри оперативных вмешательствах по поводу катаракты или глаукомы на фоне приема препарата возможно развитие синдрома интраоперационной нестабильности радужной оболочки (синдром «узкого зрачка»), что необходимо учитывать хирургу во время предоперационной подготовки пациента и при проведении операции.\u003Cbr\u003E\n\u003Cbr\u003E\nПеред началом терапии тамсулозином пациент должен быть обследован с целью исключения других заболеваний, которые могут вызывать такие же симптомы, как и ДГПЖ. Перед началом лечения и регулярно во время терапии должно выполняться пальцевое ректальное обследование и, при необходимости, определение концентрации простатического специфического антигена (ПСА).\u003Cbr\u003E\n\u003Cbr\u003E\nТак как клинических исследований тамсулозина у пациентов с почечной недостаточностью тяжелой степени не проводилось, применение препарата у пациентов с клиренсом креатинина \u003C 10 мл/мин требует соблюдения мер предосторожности.\u003Cbr\u003E\n\u003Cbr\u003E\nУ некоторых пациентов, принимающих или ранее принимавших тамсулозин, во время оперативного вмешательства по поводу катаракты и глаукомы отмечалось развитие синдрома интраоперационной нестабильности радужной оболочки глаза (синдром узкого зрачка), который может привести к осложнениям во время операции или в послеоперационном периоде. Целесообразность отмены терапии тамсулозином на 1-2 недели до операции по поводу катаракты или глаукомы до сих пор не доказана. Случаи интраоперационной нестабильности радужной оболочки глаза имели место у пациентов, прекративших прием препарата и в более ранние сроки перед операцией. Не рекомендуется начинать терапию тамсулозином у пациентов, которые планируют оперативное вмешательство по поводу катаракты или глаукомы. Во время предоперационного обследования пациентов хирург и врач-офтальмолог должны учитывать, принимает или принимал ли данный пациент тамсулозин. Это необходимо для подготовки к возможности развития во время операции синдрома интраоперационной нестабильности радужной оболочки глаза.\u003Cbr\u003E\n\u003Cbr\u003E\nВ случае развития ангионевротического отека следует немедленно прекратить прием препарата. Повторное применение тамсулозина противопоказано."},{"name":"Взаимодействие","value":"При применении тамсулозина вместе с атенололом, эналаприлом, нифедипином и теофиллином лекарственного взаимодействия обнаружено не было.\u003Cbr\u003E\n\u003Cbr\u003E\nПри одновременном применении тамсулозина с циметидином отмечено некоторое повышение концентрации тамсулозина в плазме крови; с фуросемидом - снижение концентрации, однако это не требует коррекции дозы, так как концентрация тамсулозина остается в пределах нормального диапазона. Диазепам, пропранолол, трихлорметиазид, хлормадинон, амитриптилин, диклофенак, глибенкламид, симвастатин и варфарин не изменяют свободную фракцию тамсулозина в плазме крови человека in vitro. В свою очередь, тамсулозин также не изменяет свободные фракции диазепама, пропранолола, трихлорметиазида и хлормадинона.\u003Cbr\u003E\n\u003Cbr\u003E\nВ исследованиях in vitro не было обнаружено взаимодействия на уровне печеночного метаболизма с амитриптилином, сальбутамолом, глибенкламидом и финастеридом.\u003Cbr\u003E\n\u003Cbr\u003E\nДиклофенак и варфарин могут увеличивать скорость выведения тамсулозина. Одновременное применение тамсулозина с мощными ингибиторами изофермента CYP3A4 может привести к увеличению концентрации тамсулозина. Одновременное применение с кетоконазолом (мощный ингибитор CYP3A4) приводило к увеличению площади под кривой «концентрация-время» (AUC) и максимальной концентрации (Сmах) тамсулозина в 2,8 и 2,2 раза соответственно. Тамсулозин не следует применять в комбинации с мощными ингибиторами изофермента CYP3A4 у пациентов с нарушением метаболизма изофермента CYP2D6. Препарат следует применять с осторожностью в комбинации с мощными и средней активности ингибиторами изофермента CYP3A4. Одновременное применение тамсулозина и пароксетина, мощного ингибитора изофермента CYP2D6, приводило к увеличению Сmах и AUC тамсулозина в 1,3 и 1,6 раза соответственно, однако данное увеличение признано клинически незначимым.\u003Cbr\u003E\n\u003Cbr\u003E\nОдновременное применение других блокаторов α1-адренорецепторов может привести к гипотензивному эффекту."},{"name":"Регистрационный номер","value":"ЛП-008006"},{"name":"Дата государственной регистрации","value":"01.04.2022"},{"name":"Владелец регистрационного удостоверения","value":"ПРАНАФАРМ","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["34324371:35649313","7893318:12507927"]}}},{"name":"Изготовитель","value":"ПРАНАФАРМ"},{"name":"Фасовщик","value":"ПРАНАФАРМ"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Тамсулозин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["17796364:18103256"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"13665749419564527959":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"мочеполовая система"},{"name":"Назначение","value":"дизурия, доброкачественная гиперплазия предстательной железы"},{"name":"Показания к применению","value":"Лечение дизурических расстройств, связанных с доброкачественной гиперплазией предстательной железы (ДГПЖ)."},{"name":"Противопоказания","value":"- Гиперчувствительность к тамсулозину и/или к любому из вспомогательных веществ в составе препарата, в том числе, наличие лекарственного ангионевротического отека в анамнезе.\u003Cbr\u003E\n\u003Cbr\u003E\n- Ортостатическая гипотензия (в т.ч. в анамнезе).\u003Cbr\u003E\n\u003Cbr\u003E\n- Печеночная недостаточность тяжелой степени.\u003Cbr\u003E\n\u003Cbr\u003E\n- Возраст до 18 лет.\u003Cbr\u003E\n\u003Cbr\u003E\n- Непереносимость фруктозы, дефицит сахаразы/изомальтазы, синдром глюкозо-галактозной мальабсорбции."},{"name":"Состав","value":"1 капсула содержит:\u003Cbr\u003E\n\u003Cbr\u003E\nтамсулозина гидрохлорид, субстанция-пеллеты, 0,133 % - 300,3 мг.\u003Cbr\u003E\n\u003Cbr\u003E\nСостав пеллет:\u003Cbr\u003E\n\u003Cbr\u003E\nдействующее вещество: тамсулозина гидрохлорид - 0,4 мг;\u003Cbr\u003E\n\u003Cbr\u003E\nвспомогательные вещества: ядро (75 % сахароза и 25 % крахмал) - 220,0 мг: гипромеллоза-Е5 - 1,9132 мг, натрия лаурилсульфат - 0,2 мг, дибутилфталат - 0,2088 мг, тальк - 7,5358 мг;\u003Cbr\u003E\n\u003Cbr\u003E\nоболочка: макрогол-6000 - 6,2058 мг, этилцеллюлоза - 1,7748 мг, метакриловой кислоты и этилакрилата сополимер (1:1) [30 % дисперсия] - 62,0585 мг.\u003Cbr\u003E\n\u003Cbr\u003E\nВспомогательные вещества оболочки капсулы: корпус: желатин - 100 %;\u003Cbr\u003E\n\u003Cbr\u003E\nкрышечка: титана диоксид - 1 %, железа оксид желтый - 0,7 %, индигокармин - 0,15 %, желатин - до 100 %."},{"name":"Действующее вещество","value":"Taмcyлoзин"},{"name":"Способ применения и дозы","value":"Внутрь. Принимают по 1 капсуле (0,4 мг) 1 раз в сутки после завтрака, запивая водой. Капсулу не разжевывать, так как это может повлиять на скорость высвобождения тамсулозина.\u003Cbr\u003E\n\u003Cbr\u003E\nПрименение препарата в особых клинических группах пациентов\u003Cbr\u003E\n\u003Cbr\u003E\nУ детей и подростков до 18 лет\u003Cbr\u003E\n\u003Cbr\u003E\nТамсулозин не показан к применению у детей и подростков до 18 лет.\u003Cbr\u003E\n\u003Cbr\u003E\nУ пожилых пациентов\u003Cbr\u003E\n\u003Cbr\u003E\nКоррекции дозы тамсулозина не требуется.\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов с нарушением функции почек\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов с почечной недостаточностью коррекции дозы не требуется. При применении тамсулозина у пациентов с терминальной стадией почечной недостаточности (клиренс креатинина \u003C 10 мл/мин) следует соблюдать меры предосторожности.\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов с нарушением функции печени\u003Cbr\u003E\n\u003Cbr\u003E\nУ пациентов с печеночной недостаточностью легкой и средней степени тяжести коррекции дозы не требуется. Применение тамсулозина у пациентов с печеночной недостаточностью тяжелой степени противопоказано."},{"name":"Побочные действия","value":"Представленные ниже нежелательные реакции, возможные на фоне терапии тамсулозином, распределены по системно-органным классам с указанием частоты их возникновения согласно рекомендациям ВОЗ:\u003Cbr\u003E\n\u003Cbr\u003E\nочень часто ≥ 1/10;\u003Cbr\u003E\n\u003Cbr\u003E\nчасто от ≥ 1/100 до \u003C 1/10;\u003Cbr\u003E\n\u003Cbr\u003E\nнечасто от ≥ 1/1000 до \u003C 1/100;\u003Cbr\u003E\n\u003Cbr\u003E\nредко от ≥ 1/10000 до \u003C 1/1000;\u003Cbr\u003E\n\u003Cbr\u003E\nочень редко \u003C 1/10000, включая отдельные сообщения;\u003Cbr\u003E\n\u003Cbr\u003E\nчастота неизвестна - по имеющимся данным установить частоту возникновения не представляется возможным.\u003Cbr\u003EОписаны случаи интраоперационной нестабильности радужной оболочки глаза (синдром узкого зрачка) при операции по поводу катаракты и глаукомы у пациентов, принимавших тамсулозин.\u003Cbr\u003E\n\u003Cbr\u003E\nПострегистрационное применение препарата\u003Cbr\u003E\n\u003Cbr\u003E\nПомимо нежелательных реакций, описанным выше, при использовании тамсулозина наблюдались фибрилляция предсердий, аритмия, тахикардия и отдышка. В связи с тем, что данные были получены методом спонтанных сообщений в пострегистрационном периоде применения тамсулозина, определение частоты и причинно-следственной связи данных нежелательных реакций с приемом тамсулозина представляется затруднительным.\u003Cbr\u003E\nПередозировка:\u003Cbr\u003E\nСимптомы\u003Cbr\u003E\n\u003Cbr\u003E\nПередозировка тамсулозина может вызвать серьезное снижение артериального давления и компенсаторную тахикардию.\u003Cbr\u003E\n\u003Cbr\u003E\nЛечение\u003Cbr\u003E\n\u003Cbr\u003E\nСимптоматическое. АД и частота сердечных сокращений могут восстановиться при принятии пациентом горизонтального положения. При отсутствии эффекта можно применить средства, увеличивающие объем циркулирующей крови, и, если необходимо, сосудосуживающие средства. Необходимо контролировать функцию почек. Проведение гемодиализа нецелесообразно, так как тамсулозин в значительной степени связывается с белками плазмы крови.\u003Cbr\u003E\n\u003Cbr\u003E\nДля предотвращения дальнейшего всасывания препарата целесообразно промывание желудка, прием сорбентов (активированного угля) и осмотических слабительных."},{"name":"Фармакологическое действие","value":"Тамсулозин является специфическим блокатором постсинаптических α1- адренорецепторов, находящихся в гладкой мускулатуре предстательной железы, шейки мочевого пузыря и простатической части уретры. Блокада α1- адренорецепторов тамсулозином приводит к снижению тонуса гладких мышц и улучшению оттока мочи. Одновременно уменьшаются как симптомы опорожнения, так и симптомы наполнения, обусловленные повышенным тонусом гладкой мускулатуры и детрузорной гиперактивностью при доброкачественной гиперплазии предстательной железы.\u003Cbr\u003E\n\u003Cbr\u003E\nСпособность тамсулозина воздействовать на α1-А подтип адренорецепторов в 20 раз превосходит его способность взаимодействовать с α1-В подтипом адренорецепторов, которые расположены в гладких мышцах сосудов. Благодаря своей высокой селективности, тамсулозин не вызывает клинически значимого снижения системного артериального давления (АД) как у пациентов с артериальной гипертензией, так и у пациентов с нормальным исходным АД."},{"name":"Фармакологическая группа","value":"альфа1-адреноблокатор"},{"name":"Форма выпуска","value":"капсулы с пролонгированным высвобождением"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Пол","value":"для мужчин"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С.\u003Cbr\u003E\n\u003Cbr\u003E\nХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003E\n\u003Cbr\u003E\nПередозировка тамсулозина может вызвать серьезное снижение артериального давления и компенсаторную тахикардию.\u003Cbr\u003E\n\u003Cbr\u003E\nЛечение\u003Cbr\u003E\n\u003Cbr\u003E\nСимптоматическое. АД и частота сердечных сокращений могут восстановиться при принятии пациентом горизонтального положения. При отсутствии эффекта можно применить средства, увеличивающие объем циркулирующей крови, и, если необходимо, сосудосуживающие средства. Необходимо контролировать функцию почек. Проведение гемодиализа нецелесообразно, так как тамсулозин в значительной степени связывается с белками плазмы крови.\u003Cbr\u003E\n\u003Cbr\u003E\nДля предотвращения дальнейшего всасывания препарата целесообразно промывание желудка, прием сорбентов (активированного угля) и осмотических слабительных."},{"name":"Применение при беременности и кормлении грудью","value":"Тамсулозин не показан к применению у женщин."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Данные об отрицательном влиянии на способность к управлению транспортными средствами и занятию потенциально опасными видами деятельности отсутствуют. Тем не менее, в связи с возможностью возникновения головокружения, до выяснения индивидуальной реакции пациента, следует воздержаться от занятий, требующих повышенной концентрации внимания и быстроты психомоторных реакций, в том числе от управления транспортными средствами и механизмами."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003E\nУ пациентов с почечной недостаточностью в терминальной стадии (клиренс креатинина менее 10 мл/мин); артериальной гипотензией.\u003Cbr\u003EКак и при применении других α1-адреноблокаторов, на фоне терапии тамсулозином в отдельных случаях может наблюдаться снижение АД, которое иногда может привести к обморочному состоянию. При первых признаках ортостатической гипотензии (головокружение, слабость) пациент должен сесть или лечь и оставаться в этом положении до тех пор, пока указанные симптомы не исчезнут.\u003Cbr\u003E\n\u003Cbr\u003E\nПри оперативных вмешательствах по поводу катаракты или глаукомы на фоне приема препарата возможно развитие синдрома интраоперационной нестабильности радужной оболочки (синдром «узкого зрачка»), что необходимо учитывать хирургу во время предоперационной подготовки пациента и при проведении операции.\u003Cbr\u003E\n\u003Cbr\u003E\nПеред началом терапии тамсулозином пациент должен быть обследован с целью исключения других заболеваний, которые могут вызывать такие же симптомы, как и ДГПЖ. Перед началом лечения и регулярно во время терапии должно выполняться пальцевое ректальное обследование и, при необходимости, определение концентрации простатического специфического антигена (ПСА).\u003Cbr\u003E\n\u003Cbr\u003E\nТак как клинических исследований тамсулозина у пациентов с почечной недостаточностью тяжелой степени не проводилось, применение препарата у пациентов с клиренсом креатинина \u003C 10 мл/мин требует соблюдения мер предосторожности.\u003Cbr\u003E\n\u003Cbr\u003E\nУ некоторых пациентов, принимающих или ранее принимавших тамсулозин, во время оперативного вмешательства по поводу катаракты и глаукомы отмечалось развитие синдрома интраоперационной нестабильности радужной оболочки глаза (синдром узкого зрачка), который может привести к осложнениям во время операции или в послеоперационном периоде. Целесообразность отмены терапии тамсулозином на 1-2 недели до операции по поводу катаракты или глаукомы до сих пор не доказана. Случаи интраоперационной нестабильности радужной оболочки глаза имели место у пациентов, прекративших прием препарата и в более ранние сроки перед операцией. Не рекомендуется начинать терапию тамсулозином у пациентов, которые планируют оперативное вмешательство по поводу катаракты или глаукомы. Во время предоперационного обследования пациентов хирург и врач-офтальмолог должны учитывать, принимает или принимал ли данный пациент тамсулозин. Это необходимо для подготовки к возможности развития во время операции синдрома интраоперационной нестабильности радужной оболочки глаза.\u003Cbr\u003E\n\u003Cbr\u003E\nВ случае развития ангионевротического отека следует немедленно прекратить прием препарата. Повторное применение тамсулозина противопоказано."},{"name":"Взаимодействие","value":"При применении тамсулозина вместе с атенололом, эналаприлом, нифедипином и теофиллином лекарственного взаимодействия обнаружено не было.\u003Cbr\u003E\n\u003Cbr\u003E\nПри одновременном применении тамсулозина с циметидином отмечено некоторое повышение концентрации тамсулозина в плазме крови; с фуросемидом - снижение концентрации, однако это не требует коррекции дозы, так как концентрация тамсулозина остается в пределах нормального диапазона. Диазепам, пропранолол, трихлорметиазид, хлормадинон, амитриптилин, диклофенак, глибенкламид, симвастатин и варфарин не изменяют свободную фракцию тамсулозина в плазме крови человека in vitro. В свою очередь, тамсулозин также не изменяет свободные фракции диазепама, пропранолола, трихлорметиазида и хлормадинона.\u003Cbr\u003E\n\u003Cbr\u003E\nВ исследованиях in vitro не было обнаружено взаимодействия на уровне печеночного метаболизма с амитриптилином, сальбутамолом, глибенкламидом и финастеридом.\u003Cbr\u003E\n\u003Cbr\u003E\nДиклофенак и варфарин могут увеличивать скорость выведения тамсулозина. Одновременное применение тамсулозина с мощными ингибиторами изофермента CYP3A4 может привести к увеличению концентрации тамсулозина. Одновременное применение с кетоконазолом (мощный ингибитор CYP3A4) приводило к увеличению площади под кривой «концентрация-время» (AUC) и максимальной концентрации (Сmах) тамсулозина в 2,8 и 2,2 раза соответственно. Тамсулозин не следует применять в комбинации с мощными ингибиторами изофермента CYP3A4 у пациентов с нарушением метаболизма изофермента CYP2D6. 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Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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954 ₽

Скидка: 21%
–21 %
Вместо:1 207 ₽
  • 11-13 июня, самовывоз • 0 ₽
POLZAru
Рейтинг 4.9 из 5
38Котзывов
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  • Тамсулозин капс. с пролонг. высвоб., 0.4 мг, 30 шт.
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    Тамсулозин капс. с пролонг. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 615 ₽
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  • Тамсулозин Канон капс. кш/раств. с пролонг. высвоб., 0.4 мг, 30 шт.
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    Рейтинг товара: 4.6 из 5
    на основе 23 оценки
    Цена 403 ₽
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  • Тамсулозин Канон таб. пролонг. высвоб. п/о плен. плён., 0.4 мг, 30 шт.
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    Тамсулозин Канон таб. пролонг. высвоб. п/о плен. плён., 0.4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 28 оценок
    Цена 383 ₽
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  • Тамсулозин Реневал капс. киш./раств. пролонг. высв., 400 мкг, 30 шт.
    –11 %
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    Тамсулозин Реневал капс. киш./раств. пролонг. высв., 400 мкг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    Цена 406 ₽ вместо 456
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  • Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.
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    Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 19 оценок
    Цена 431 ₽
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  • Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.
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    Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 4.6 из 5
    на основе 24 оценки
    Цена 800 ₽
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  • Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.
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    Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 687 ₽
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  • Тамсулозин капс. пролонг. высв., 0.4 мг, 30 шт.
    –16 %
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    Тамсулозин капс. пролонг. высв., 0.4 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 509 ₽ вместо 608
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  • Тамсулозин-Вертекс таб. пролонг. высвоб. п/о плен., 0.4 мг, 30 шт.
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    Тамсулозин-Вертекс таб. пролонг. высвоб. п/о плен., 0.4 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 19 оценок
    Цена 445 ₽
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  • Тамсулозин-obl капс. модиф. высвоб., 0.4 мг, 30 шт.
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    Тамсулозин-obl капс. модиф. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 3 из 5
    на основе 2 оценки
    Цена 621 ₽
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  • Омник Окас таб. контр. высвоб. п/о, 0.4 мг, 30 шт.
    –21 %
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    Омник Окас таб. контр. высвоб. п/о, 0.4 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 21 оценка
    Цена 793 ₽ вместо 1 003
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  • Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8oqjqpk9nrc/toggleWishlist":{"skuId":"101820478797","productId":1770271272,"offerId":"YtkD2SGWr0LBkBv-buD5eg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQ+Y+doNvy+uSJARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCKjkkMwGEM3q5Kf7AhiS4NAHIO7cwQc=","sign":"MFc3IGRFJ6j3NcH0dgRuQ0gvjW2OSLSjBu2XHMkfdo4="},"waitWishlistCollections":false}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8oqjqpk9nrc/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 30 оценок
    Цена 760 ₽
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Инструкция

Показания к применению

Лечение дизурических расстройств, связанных с доброкачественной гиперплазией предстательной железы (ДГПЖ).

Противопоказания

- Гиперчувствительность к тамсулозину и/или к любому из вспомогательных веществ в составе препарата, в том числе, наличие лекарственного ангионевротического отека в анамнезе.

- Ортостатическая гипотензия (в т.ч. в анамнезе).

- Печеночная недостаточность тяжелой степени.

- Возраст до 18 лет.

- Непереносимость фруктозы, дефицит сахаразы/изомальтазы, синдром глюкозо-галактозной мальабсорбции.

Способ применения и дозы

Внутрь. Принимают по 1 капсуле (0,4 мг) 1 раз в сутки после завтрака, запивая водой. Капсулу не разжевывать, так как это может повлиять на скорость высвобождения тамсулозина.

Применение препарата в особых клинических группах пациентов

У детей и подростков до 18 лет

Тамсулозин не показан к применению у детей и подростков до 18 лет.

У пожилых пациентов

Коррекции дозы тамсулозина не требуется.

У пациентов с нарушением функции почек

У пациентов с почечной недостаточностью коррекции дозы не требуется. При применении тамсулозина у пациентов с терминальной стадией почечной недостаточности (клиренс креатинина < 10 мл/мин) следует соблюдать меры предосторожности.

У пациентов с нарушением функции печени

У пациентов с печеночной недостаточностью легкой и средней степени тяжести коррекции дозы не требуется. Применение тамсулозина у пациентов с печеночной недостаточностью тяжелой степени противопоказано.
Полная инструкция
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ТАМСУЛОЗИН капс. с пролонг. высвоб.
ТАМСУЛОЗИН капс. с пролонг. высвоб., 0.4 мг, 90 шт.
4.3
(14)
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Инструкция

954 ₽

Скидка: 21%
–21 %
Вместо:1 207 ₽
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4.3
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У продавца:14 оценок·4 отзыва
У всех продавцов:15 оценок·5 отзывов
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user avatar
3 месяца назад • Валерий Кубынин • Куплен на Маркете
Достоинства: Помогает. Пью не первый месяц. Реже бегаешь в туалет
Недостатки: хуже нет.
Комментарий: рекомендую.
user avatar
6 дней назад • Виктор Федосеенко • Куплен на Маркете
Достоинства: спасибо
user avatar
2 месяца назад • Нурсен Шаршеев • Куплен на Маркете
Достоинства: пустышка
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